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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs1044506
log Bayes Factor = 157.763
Chromosome 6   position 32,172,065  (GRCh37) Explore rs1044506 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
H36.0 Diabetic retinopathy
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
G35 Multiple sclerosis
1.000 0.000 0.000
I10 Essential (primary) hypertension
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
I20-I25 Ischaemic heart diseases
0.000 0.000 1.000
Chapter IX Diseases of the circulatory system
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
# Top node
0.000 0.000 1.000
E78.0 Pure hypercholesterolaemia
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
I10-I15 Hypertensive diseases
0.000 0.000 1.000
E10.1 With ketoacidosis
0.000 0.000 1.000
E11.9 Without complications
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
Chapter VII Diseases of the eye and adnexa
0.000 0.000 1.000
Chapter XI Diseases of the digestive system
0.000 0.000 1.000
H36 Retinal disorders in diseases classified elsewhere
0.000 0.000 1.000
L40 Psoriasis
0.000 0.000 1.000
H30-H36 Disorders of choroid and retina
0.000 0.000 1.000
E14 Unspecified diabetes mellitus
0.000 0.000 1.000
I25 Chronic ischaemic heart disease
0.000 0.000 1.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.000 1.000
L40-L45 Papulosquamous disorders
0.000 0.000 1.000
E16 Other disorders of pancreatic internal secretion
0.000 0.000 1.000
E16.2 Hypoglycaemia, unspecified
0.000 0.000 1.000
E83.1 Disorders of iron metabolism
1.000 0.000 0.000
I20 Angina pectoris
0.000 0.001 0.999
M06 Other rheumatoid arthritis
0.000 0.001 0.999
L43 Lichen planus
0.000 0.001 0.999
L40.5 Arthropathic psoriasis
0.000 0.002 0.998
K90 Intestinal malabsorption
0.000 0.002 0.998
K90-K93 Other diseases of the digestive system
0.000 0.002 0.998
L43.9 Lichen planus, unspecified
0.000 0.002 0.998
E10.4 With neurological complications
0.000 0.003 0.997
G35-G37 Demyelinating diseases of the central nervous system
0.997 0.003 0.000
M05-M14 Inflammatory polyarthropathies
0.000 0.005 0.995
G37 Other demyelinating diseases of central nervous system
0.995 0.005 0.000
K51.9 Ulcerative colitis, unspecified
0.994 0.006 0.000
K51 Ulcerative colitis
0.994 0.006 0.000
E14.3 With ophthalmic complications
0.000 0.006 0.994
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.007 0.993
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.007 0.993
L40.9 Psoriasis, unspecified
0.000 0.007 0.993
E70-E90 Metabolic disorders
0.000 0.008 0.992
I22 Subsequent myocardial infarction
0.000 0.008 0.992
G37.9 Demyelinating disease of central nervous system, unspecified
0.991 0.009 0.000
E14.9 Without complications
0.000 0.011 0.989
M05 Seropositive rheumatoid arthritis
0.000 0.012 0.988
I20.0 Unstable angina
0.000 0.013 0.987
I20.9 Angina pectoris, unspecified
0.000 0.013 0.987
H43-H45 Disorders of vitreous body and globe
0.000 0.015 0.985
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.015 0.985
K51.3 Ulcerative (chronic) rectosigmoiditis
0.985 0.015 0.000
H40-H42 Glaucoma
0.000 0.016 0.984
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.017 0.983
E11.3 With ophthalmic complications
0.000 0.019 0.981
H43 Disorders of vitreous body
0.000 0.020 0.980
K70-K77 Diseases of liver
0.000 0.021 0.979
K50-K52 Noninfective enteritis and colitis
0.007 0.026 0.967
H40.9 Glaucoma, unspecified
0.000 0.027 0.973
H40 Glaucoma
0.000 0.027 0.973
I30-I52 Other forms of heart disease
0.000 0.028 0.972
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.030 0.970
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.030 0.970
E10.5 With peripheral circulatory complications
0.000 0.030 0.970
J45.9 Asthma, unspecified
0.000 0.035 0.965
I35 Nonrheumatic aortic valve disorders
0.000 0.036 0.964
I35.0 Aortic (valve) stenosis
0.000 0.036 0.964
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.036 0.964
I25.1 Atherosclerotic heart disease
0.000 0.037 0.963
I47 Paroxysmal tachycardia
0.000 0.038 0.962
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.044 0.956
K74 Fibrosis and cirrhosis of liver
0.000 0.046 0.954
H43.8 Other disorders of vitreous body
0.000 0.052 0.948
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.053 0.947
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.056 0.944
I47.1 Supraventricular tachycardia
0.000 0.057 0.943
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.000 0.058 0.942
K55-K64 Other diseases of intestines
0.000 0.058 0.942
K50 Crohn's disease [regional enteritis]
0.000 0.059 0.941
H34 Retinal vascular occlusions
0.000 0.060 0.940
I24 Other acute ischaemic heart diseases
0.000 0.060 0.940
I25.2 Old myocardial infarction
0.000 0.061 0.939
K60 Fissure and fistula of anal and rectal regions
0.000 0.062 0.938
H43.3 Other vitreous opacities
0.000 0.063 0.937
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.000 0.064 0.936
I25.5 Ischaemic cardiomyopathy
0.000 0.064 0.936
K74.3 Primary biliary cirrhosis
0.000 0.066 0.934
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.072 0.928
K82 Other diseases of gallbladder
0.000 0.072 0.928
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.073 0.927
I20.1 Angina pectoris with documented spasm
0.000 0.074 0.926
K51.8 Other ulcerative colitis
0.923 0.077 0.000
K60.2 Anal fissure, unspecified
0.000 0.078 0.922
E05.9 Thyrotoxicosis, unspecified
0.000 0.078 0.922
I12 Hypertensive renal disease
0.000 0.079 0.921
E07 Other disorders of thyroid
0.000 0.079 0.921
K82.8 Other specified diseases of gallbladder
0.000 0.080 0.920
E11.1 With ketoacidosis
0.000 0.084 0.916
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.086 0.914
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.101 0.899
E13 Other specified diabetes mellitus
0.000 0.105 0.895
E11.2 With renal complications
0.000 0.105 0.895
I46 Cardiac arrest
0.000 0.106 0.894
Chapter VIII Diseases of the ear and mastoid process
0.000 0.106 0.894
I21 Acute myocardial infarction
0.000 0.107 0.893
E10.2 With renal complications
0.000 0.108 0.892
K72 Hepatic failure, not elsewhere classified
0.000 0.110 0.890
G37.8 Other specified demyelinating diseases of central nervous system
0.890 0.110 0.000
M07 Psoriatic and enteropathic arthropathies
0.000 0.115 0.885
E11.5 With peripheral circulatory complications
0.000 0.116 0.884
K60.0 Acute anal fissure
0.000 0.116 0.884
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.118 0.882
K51.2 Ulcerative (chronic) proctitis
0.878 0.122 0.000
I15 Secondary hypertension
0.000 0.123 0.877
E07.9 Disorder of thyroid, unspecified
0.000 0.124 0.876
E03.8 Other specified hypothyroidism
0.000 0.125 0.875
H34.2 Other retinal artery occlusions
0.000 0.130 0.870
M06.3 Rheumatoid nodule
0.000 0.131 0.869
K55 Vascular disorders of intestine
0.000 0.134 0.866
K51.5 Mucosal proctocolitis
0.859 0.141 0.000
I31 Other diseases of pericardium
0.000 0.143 0.857
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.144 0.856
K60.5 Anorectal fistula
0.000 0.147 0.853
I12.9 Hypertensive renal disease without renal failure
0.000 0.147 0.853
I46.9 Cardiac arrest, unspecified
0.000 0.153 0.847
K63 Other diseases of intestine
0.000 0.156 0.844
M06.4 Inflammatory polyarthropathy
0.000 0.157 0.843
H60-H62 Diseases of external ear
0.000 0.157 0.843
H65-H75 Diseases of middle ear and mastoid
0.000 0.158 0.842
E83 Disorders of mineral metabolism
0.787 0.160 0.054
K50.8 Other Crohn's disease
0.000 0.160 0.840
K75 Other inflammatory liver diseases
0.000 0.160 0.840
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.162 0.838
I21.2 Acute transmural myocardial infarction of other sites
0.000 0.168 0.832
J45 Asthma
0.000 0.174 0.826
E06 Thyroiditis
0.000 0.177 0.823
K50.0 Crohn's disease of small intestine
0.000 0.179 0.821
K73 Chronic hepatitis, not elsewhere classified
0.000 0.179 0.821
E13.9 Without complications
0.000 0.180 0.820
K58 Irritable bowel syndrome
0.000 0.180 0.820
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.182 0.818
K55.2 Angiodysplasia of colon
0.000 0.186 0.814
K81 Cholecystitis
0.000 0.186 0.814
I21.9 Acute myocardial infarction, unspecified
0.000 0.193 0.807
M07.3 Other psoriatic arthropathies
0.000 0.195 0.805
K50.9 Crohn's disease, unspecified
0.000 0.201 0.799
H40.1 Primary open-angle glaucoma
0.000 0.202 0.798
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.202 0.798
K63.9 Disease of intestine, unspecified
0.000 0.202 0.798
K82.1 Hydrops of gallbladder
0.000 0.205 0.795
K72.9 Hepatic failure, unspecified
0.000 0.206 0.794
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.207 0.793
E74 Other disorders of carbohydrate metabolism
0.000 0.208 0.792
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.214 0.786
K74.6 Other and unspecified cirrhosis of liver
0.000 0.218 0.782
H71 Cholesteatoma of middle ear
0.000 0.220 0.780
L40.8 Other psoriasis
0.000 0.220 0.780
K58.0 Irritable bowel syndrome with diarrhoea
0.000 0.221 0.779
I35.8 Other aortic valve disorders
0.000 0.221 0.779
J40-J47 Chronic lower respiratory diseases
0.000 0.221 0.779
E16.1 Other hypoglycaemia
0.000 0.222 0.778
K52 Other non-infective gastro-enteritis and colitis
0.001 0.224 0.775
I21.4 Acute subendocardial myocardial infarction
0.000 0.225 0.775
K80 Cholelithiasis
0.000 0.225 0.775
K80.2 Calculus of gallbladder without cholecystitis
0.000 0.225 0.775
I15.1 Hypertension secondary to other renal disorders
0.000 0.225 0.775
Chapter X Diseases of the respiratory system
0.000 0.226 0.774
E11.4 With neurological complications
0.000 0.226 0.773
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.771 0.229 0.000
I31.3 Pericardial effusion (noninflammatory)
0.000 0.230 0.770
I47.0 Reentry ventricular arrhythmia
0.000 0.231 0.769
L43.8 Other lichen planus
0.000 0.232 0.768
K75.4 Autoimmune hepatitis
0.000 0.233 0.767
I47.9 Paroxysmal tachycardia, unspecified
0.000 0.234 0.766
H60 Otitis externa
0.000 0.235 0.765
M45-M49 Spondylopathies
0.000 0.235 0.765
E40-E46 Malnutrition
0.000 0.236 0.764
I23 Certain current complications following acute myocardial infarction
0.000 0.238 0.762
I47.2 Ventricular tachycardia
0.000 0.239 0.761
K55.8 Other vascular disorders of intestine
0.000 0.241 0.759
E14.4 With neurological complications
0.000 0.241 0.758
K63.3 Ulcer of intestine
0.000 0.242 0.758
E78.2 Mixed hyperlipidaemia
0.000 0.243 0.757
H66 Suppurative and unspecified otitis media
0.000 0.243 0.757
I25.3 Aneurysm of heart
0.000 0.244 0.755
M06.34 Rheumatoid nodule (Hand)
0.000 0.246 0.754
H34.8 Other retinal vascular occlusions
0.000 0.247 0.753
E78.1 Pure hyperglyceridaemia
0.000 0.249 0.751
K81.1 Chronic cholecystitis
0.000 0.249 0.751
E11.0 With coma
0.000 0.249 0.751
E11.6 With other specified complications
0.000 0.253 0.747
M45 Ankylosing spondylitis
0.000 0.253 0.747
H43.9 Disorder of vitreous body, unspecified
0.000 0.254 0.746
E83.3 Disorders of phosphorus metabolism
0.731 0.255 0.014
H66.3 Other chronic suppurative otitis media
0.000 0.256 0.744
K51.0 Ulcerative (chronic) enterocolitis
0.742 0.258 0.000
E88 Other metabolic disorders
0.000 0.259 0.741
H43.1 Vitreous haemorrhage
0.000 0.261 0.738
K50.1 Crohn's disease of large intestine
0.000 0.263 0.737
K81.9 Cholecystitis, unspecified
0.000 0.268 0.732
H30 Chorioretinal inflammation
0.000 0.268 0.731
M11 Other crystal arthropathies
0.000 0.269 0.731
H35 Other retinal disorders
0.000 0.270 0.730
H61 Other disorders of external ear
0.000 0.270 0.730
K82.9 Disease of gallbladder, unspecified
0.000 0.271 0.729
Chapter VI Diseases of the nervous system
0.723 0.271 0.006
I30 Acute pericarditis
0.000 0.272 0.728
E06.3 Autoimmune thyroiditis
0.000 0.273 0.727
K72.0 Acute and subacute hepatic failure
0.000 0.277 0.723
K82.2 Perforation of gallbladder
0.000 0.277 0.723
M45.X9 Ankylosing spondylitis (Site unspecified)
0.000 0.278 0.722
H25-H28 Disorders of lens
0.000 0.279 0.721
I25.4 Coronary artery aneurysm
0.000 0.281 0.719
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.000 0.282 0.718
E10.8 With unspecified complications
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.283 0.717
E10.6 With other specified complications
0.000 0.283 0.717
E10.0 With coma
0.000 0.283 0.717
E11.7 With multiple complications
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
I13 Hypertensive heart and renal disease
0.000 0.283 0.717
I00-I02 Acute rheumatic fever
0.000 0.283 0.717
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.1 Congenital hypothyroidism without goitre
0.000 0.283 0.717
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.717
H36.8 Other retinal disorders in diseases classified elsewhere
0.000 0.283 0.717
L40.4 Guttate psoriasis
0.000 0.283 0.717
L40.3 Pustulosis palmaris et plantaris
0.000 0.283 0.717
L40.2 Acrodermatitis continua
0.000 0.283 0.717
L40.1 Generalised pustular psoriasis
0.000 0.283 0.717
H32 Chorioretinal disorders in diseases classified elsewhere
0.000 0.283 0.717
E14.8 With unspecified complications
0.000 0.283 0.717
E14.7 With multiple complications
0.000 0.283 0.717
E14.6 With other specified complications
0.000 0.283 0.717
E14.5 With peripheral circulatory complications
0.000 0.283 0.717
E14.2 Withrenal complications
0.000 0.283 0.717
E14.1 With ketoacidosis
0.000 0.283 0.717
E14.0 With coma
0.000 0.283 0.717
I25.6 Silent myocardial ischaemia
0.000 0.283 0.717
E15 Nondiabetic hypoglycaemic coma
0.000 0.283 0.717
L44 Other papulosquamous disorders
0.000 0.283 0.717
L41 Parapsoriasis
0.000 0.283 0.717
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.283 0.717
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.283 0.717
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.283 0.717
E16.4 Abnormal secretion of gastrin
0.000 0.283 0.717
E16.3 Increased secretion of glucagon
0.000 0.283 0.717
M06.8 Other specified rheumatoid arthritis
0.000 0.284 0.716
M06.2 Rheumatoid bursitis
0.000 0.284 0.716
M06.1 Adult-onset Still's disease
0.000 0.284 0.716
L43.3 Subacute (active) lichen planus
0.000 0.284 0.716
L43.2 Lichenoid drug reaction
0.000 0.284 0.716
L43.1 Bullous lichen planus
0.000 0.284 0.716
L43.0 Hypertrophic lichen planus
0.000 0.284 0.716
K90.3 Pancreatic steatorrhoea
0.000 0.284 0.716
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.284 0.716
K90.1 Tropical sprue
0.000 0.284 0.716
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.284 0.715
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.285 0.715
G36 Other acute disseminated demyelination
0.715 0.285 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.286 0.714
M08 Juvenile arthritis
0.000 0.286 0.714
G37.5 Concentric sclerosis [Balo]
0.714 0.286 0.000
G37.4 Subacute necrotising myelitis
0.714 0.286 0.000
G37.2 Central pontine myelinolysis
0.714 0.286 0.000
G37.1 Central demyelination of corpus callosum
0.714 0.286 0.000
G37.0 Diffuse sclerosis
0.714 0.286 0.000
H74 Other disorders of middle ear and mastoid
0.000 0.286 0.714
E78.6 Lipoprotein deficiency
0.000 0.288 0.712
E78.3 Hyperchylomicronaemia
0.000 0.288 0.712
G80-G83 Cerebral palsy and other paralytic syndromes
0.711 0.288 0.002
E77 Disorders of glycoprotein metabolism
0.000 0.288 0.711
E76 Disorders of glycosaminoglycan metabolism
0.000 0.288 0.711
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.288 0.711
E72 Other disorders of amino-acid metabolism
0.000 0.288 0.711
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.288 0.711
E70 Disorders of aromatic amino-acid metabolism
0.000 0.288 0.711
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.288 0.711
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.000 0.290 0.710
K51.4 Pseudopolyposis of colon
0.710 0.290 0.000
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.290 0.710
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.291 0.709
M05.8 Other seropositive rheumatoid arthritis
0.000 0.292 0.708
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.292 0.708
M05.2 Rheumatoid vasculitis
0.000 0.292 0.708
M05.1 Rheumatoid lung disease
0.000 0.292 0.708
M05.0 Felty's syndrome
0.000 0.292 0.708
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.292 0.708
H34.1 Central retinal artery occlusion
0.000 0.293 0.707
H45 Disorders of vitreous body and globe in diseases classified elsewhere
0.000 0.293 0.706
H42 Glaucoma in diseases classified elsewhere
0.000 0.294 0.706
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.295 0.705
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.295 0.705
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.295 0.705
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.295 0.705
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.295 0.705
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.295 0.705
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.295 0.705
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.295 0.705
K52.1 Toxic gastro-enteritis and colitis
0.000 0.295 0.704
I12.0 Hypertensive renal disease with renal failure
0.000 0.296 0.704
K51.1 Ulcerative (chronic) ileocolitis
0.703 0.296 0.000
H43.2 Crystalline deposits in vitreous body
0.000 0.297 0.703
H43.0 Vitreous prolapse
0.000 0.297 0.703
K77 Liver disorders in diseases classified elsewhere
0.000 0.298 0.702
K71 Toxic liver disease
0.000 0.298 0.702
I51 Complications and ill-defined descriptions of heart disease
0.000 0.299 0.701
E78.8 Other disorders of lipoprotein metabolism
0.000 0.301 0.699
J95-J99 Other diseases of the respiratory system
0.000 0.302 0.698
H40.6 Glaucoma secondary to drugs
0.000 0.302 0.698
H40.4 Glaucoma secondary to eye inflammation
0.000 0.302 0.698
H40.3 Glaucoma secondary to eye trauma
0.000 0.302 0.698
I52 Other heart disorders in diseases classified elsewhere
0.000 0.303 0.697
I48 Atrial fibrillation and flutter
0.000 0.303 0.697
I41 Myocarditis in diseases classified elsewhere
0.000 0.303 0.697
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.000 0.303 0.697
I32 Pericarditis in diseases classified elsewhere
0.000 0.303 0.697
K74.5 Biliary cirrhosis, unspecified
0.000 0.304 0.696
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.000 0.305 0.695
I11 Hypertensive heart disease
0.000 0.305 0.695
H40.5 Glaucoma secondary to other eye disorders
0.000 0.306 0.694
E89.3 Postprocedural hypopituitarism
0.000 0.306 0.694
E11.8 With unspecified complications
0.000 0.306 0.694
M65-M68 Disorders of synovium and tendon
0.000 0.309 0.691
J46 Status asthmaticus
0.000 0.310 0.690
I31.9 Disease of pericardium, unspecified
0.000 0.312 0.688
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.314 0.686
K74.4 Secondary biliary cirrhosis
0.000 0.316 0.684
K74.2 Hepatic fibrosis with hepatic sclerosis
0.000 0.316 0.684
K74.1 Hepatic sclerosis
0.000 0.316 0.684
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.317 0.683
Q60-Q64 Congenital malformations of the urinary system
0.000 0.318 0.682
L40.0 Psoriasis vulgaris
0.000 0.318 0.682
K63.4 Enteroptosis
0.000 0.319 0.681
L42 Pityriasis rosea
0.000 0.320 0.680
E05.5 Thyroid crisis or storm
0.000 0.321 0.679
E05.4 Thyrotoxicosis factitia
0.000 0.321 0.679
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.321 0.679
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.321 0.679
G81 Hemiplegia
0.678 0.321 0.001
E89.0 Postprocedural hypothyroidism
0.000 0.322 0.678
K64 Haemorrhoids and perianal venous thrombosis
0.000 0.325 0.675
E79 Disorders of purine and pyrimidine metabolism
0.000 0.326 0.674
H34.9 Retinal vascular occlusion, unspecified
0.000 0.326 0.674
H34.0 Transient retinal artery occlusion
0.000 0.326 0.674
K82.3 Fistula of gallbladder
0.000 0.326 0.674
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.000 0.329 0.671
Q61 Cystic kidney disease
0.000 0.329 0.671
K73.9 Chronic hepatitis, unspecified
0.000 0.329 0.670
G83 Other paralytic syndromes
0.670 0.330 0.001
I51.8 Other ill-defined heart diseases
0.000 0.331 0.669
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.332 0.668
H27 Other disorders of lens
0.000 0.333 0.667
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.333 0.667
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.335 0.665
I15.9 Seconday hypertension, unspecified
0.000 0.336 0.664
E83.9 Disorder of mineral metabolism, unspecified
0.630 0.337 0.033
M14 Arthropathies in other diseases classified elsewhere
0.000 0.337 0.663
J86 Pyothorax
0.000 0.339 0.661
E78.4 Other hyperlipidaemia
0.000 0.339 0.661
E07.1 Dyshormogenetic goitre
0.000 0.340 0.660
E07.0 Hypersecretion of calcitonin
0.000 0.340 0.660
E84 Cystic fibrosis
0.000 0.340 0.660
G81.9 Hemiplegia, unspecified
0.658 0.342 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.342 0.658
I40 Acute myocarditis
0.000 0.344 0.656
E89.2 Postprocedural hypoparathyroidism
0.000 0.344 0.656
H60.9 Otitis externa, unspecified
0.000 0.346 0.654
M12 Other specific arthropathies
0.000 0.348 0.652
I43 Cardiomyopathy in diseases classified elsewhere
0.000 0.349 0.651
K55.1 Chronic vascular disorders of intestine
0.000 0.350 0.650
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.352 0.648
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.353 0.647
K73.2 Chronic active hepatitis, not elsewhere classified
0.000 0.355 0.645
G30-G32 Other degenerative diseases of the nervous system
0.641 0.356 0.002
E13.8 With unspecified complications
0.000 0.358 0.642
E13.7 With multiple complications
0.000 0.358 0.642
E13.6 With other specified complications
0.000 0.358 0.642
E13.5 With peripheral circulatory complications
0.000 0.358 0.642
E13.4 With neurological complications
0.000 0.358 0.642
E13.3 With ophthalmic complications
0.000 0.358 0.642
E13.2 With renal complications
0.000 0.358 0.642
E13.1 With ketoacidosis
0.000 0.358 0.642
E13.0 With coma
0.000 0.358 0.642
I22.8 Subsequent myocardial infarction of other sites
0.000 0.358 0.642
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.359 0.641
I46.1 Sudden cardiac death, so described
0.000 0.359 0.641
I21.X Presumed acute myicardial infaction (unconfirmed)
0.000 0.359 0.640
K90.9 Intestinal malabsorption, unspecified
0.000 0.361 0.639
M06.0 Seronegative rheumatoid arthritis
0.000 0.361 0.639
K72.1 Chronic hepatic failure
0.000 0.362 0.638
Q50-Q56 Congenital malformations of genital organs
0.000 0.363 0.637
K90.8 Other intestinal malabsorption
0.000 0.364 0.636
K52.9 Non-infective gastro-enteritis and colitis, unspecified
0.000 0.364 0.636
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.000 0.365 0.635
M07.6 Other enteropathic arthropathies
0.000 0.366 0.634
M07.5 Arthropathy in ulcerative colitis
0.000 0.366 0.634
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.000 0.366 0.634
M07.2 Psoriatic spondylitis
0.000 0.366 0.634
M07.1 Arthritis mutilans
0.000 0.366 0.634
M07.0 Distal interphalangeal psoriatic arthropathy
0.000 0.366 0.634
G83.4 Cauda equina syndrome
0.633 0.367 0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.000 0.367 0.633
H61.1 Non-infective disorders of pinna
0.000 0.370 0.630
I15.8 Other secondary hypertension
0.000 0.371 0.629
I15.2 Hypertension secondary to endocrine disorders
0.000 0.371 0.629
I15.0 Renovascular hypertension
0.000 0.371 0.629
H60.1 Cellulitis of external ear
0.000 0.373 0.627
I37 Pulmonary valve disorders
0.000 0.374 0.626
J98 Other respiratory disorders
0.000 0.376 0.624
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.377 0.623
M06.38 Rheumatoid nodule (Other)
0.000 0.377 0.623
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.377 0.623
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.377 0.623
M06.33 Rheumatoid nodule (Forearm)
0.000 0.377 0.623
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.377 0.623
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.377 0.623
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.377 0.623
K60.4 Rectal fistula
0.000 0.377 0.622
K63.8 Other specified diseases of intestine
0.000 0.377 0.623
K63.2 Fistula of intestine
0.000 0.378 0.621
H53-H54 Visual disturbances and blindness
0.000 0.381 0.619
H65 Nonsuppurative otitis media
0.000 0.383 0.617
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.000 0.384 0.616
H35.5 Hereditary retinal dystrophy
0.000 0.384 0.616
G20-G26 Extrapyramidal and movement disorders
0.613 0.385 0.002
I31.8 Other specified diseases of pericardium
0.000 0.385 0.615
I31.2 Haemopericardium, not elsewhere classified
0.000 0.385 0.615
I31.0 Chronic adhesive pericarditis
0.000 0.385 0.615
K75.0 Abscess of liver
0.000 0.386 0.614
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.386 0.613
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.386 0.613
E89.5 Postprocedural testicular hypofunction
0.000 0.386 0.613
E89.1 Postprocedural hypoinsulinaemia
0.000 0.386 0.613
M65 Synovitis and tenosynovitis
0.000 0.388 0.612
H35.2 Other proliferative retinopathy
0.000 0.390 0.610
I24.1 Dressler's syndrome
0.000 0.391 0.609
Q61.3 Polycystic kidney, unspecified
0.000 0.391 0.609
K65-K67 Diseases of peritoneum
0.000 0.391 0.608
H35.8 Other specified retinal disorders
0.000 0.393 0.607
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.395 0.605
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.395 0.605
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.395 0.605
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.395 0.605
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.395 0.605
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.395 0.605
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.395 0.605
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.395 0.605
H62 Disorders of external ear in diseases classified elsewhere
0.000 0.396 0.604
H46-H48 Disorders of optic nerve and visual pathways
0.000 0.396 0.604
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.000 0.396 0.604
H68 Eustachian salpingitis and obstruction
0.000 0.396 0.604
H67 Otitis media in diseases classified elsewhere
0.000 0.396 0.604
Q61.0 Congenital single renal cyst
0.000 0.396 0.604
E83.8 Other disorders of mineral metabolism
0.564 0.397 0.039
E83.2 Disorders of zinc metabolism
0.564 0.397 0.039
E83.0 Disorders of copper metabolism
0.564 0.397 0.039
K75.3 Granulomatous hepatitis, not elsewhere classified
0.000 0.398 0.602
K75.2 Nonspecific reactive hepatitis
0.000 0.398 0.602
K75.1 Phlebitis of portal vein
0.000 0.398 0.602
Q61.2 Polycystic kidney, adult type
0.000 0.399 0.601
I35.2 Aortic (valve) stenosis with insufficiency
0.000 0.399 0.601
H74.8 Other specified disorders of middle ear and mastoid
0.000 0.399 0.601
K82.0 Obstruction of gallbladder
0.000 0.401 0.599
M70-M79 Other soft tissue disorders
0.000 0.401 0.599
I45 Other conduction disorders
0.000 0.402 0.598
J43 Emphysema
0.000 0.402 0.598
K80.8 Other cholelithiasis
0.000 0.402 0.598
H60.8 Other otitis externa
0.000 0.403 0.597
I44 Atrioventricular and left bundle-branch block
0.000 0.403 0.597
K75.9 Inflammatory liver disease, unspecified
0.000 0.403 0.597
E46 Unspecified protein-energy malnutrition
0.000 0.405 0.595
M46 Other inflammatory spondylopathies
0.000 0.406 0.594
H61.3 Acquired stenosis of external ear canal
0.000 0.406 0.594
E07.8 Other specified disorders of thyroid
0.000 0.406 0.594
L10-L14 Bullous disorders
0.000 0.408 0.592
J45.8 Mixed asthma
0.000 0.408 0.592
J45.1 Nonallergic asthma
0.000 0.408 0.592
Q80-Q89 Other congenital malformations
0.000 0.408 0.592
I23.8 Other current complications following acute myocardial infarction
0.000 0.409 0.591
E06.5 Other chronic thyroiditis
0.000 0.410 0.590
E06.4 Drug-induced thyroiditis
0.000 0.410 0.590
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.410 0.590
E06.1 Subacute thyroiditis
0.000 0.410 0.590
E06.0 Acute thyroiditis
0.000 0.410 0.590

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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