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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs10456370
log Bayes Factor = 48.3883
Chromosome 6   position 29,280,736  (GRCh37) Explore rs10456370 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E83.1 Disorders of iron metabolism
1.000 0.000 0.000
K90.0 Coeliac disease
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.001 0.999
E10.9 Without complications
0.000 0.003 0.997
E05.9 Thyrotoxicosis, unspecified
0.000 0.004 0.996
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.007 0.993
E10-E14 Diabetes mellitus
0.000 0.011 0.989
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.017 0.983
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.018 0.982
E16 Other disorders of pancreatic internal secretion
0.000 0.018 0.982
E16.2 Hypoglycaemia, unspecified
0.000 0.018 0.982
E00-E07 Disorders of thyroid gland
0.000 0.020 0.980
E10.3 With ophthalmic complications
0.000 0.023 0.977
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.037 0.963
E10.2 With renal complications
0.000 0.052 0.948
E10.4 With neurological complications
0.000 0.068 0.932
E10.1 With ketoacidosis
0.000 0.095 0.905
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.871 0.129 0.000
E14 Unspecified diabetes mellitus
0.000 0.182 0.818
E13 Other specified diabetes mellitus
0.000 0.192 0.807
E16.1 Other hypoglycaemia
0.000 0.211 0.789
E05.8 Other thyrotoxicosis
0.000 0.212 0.788
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.228 0.772
E14.3 With ophthalmic complications
0.000 0.253 0.747
E05.5 Thyroid crisis or storm
0.000 0.288 0.712
E05.4 Thyrotoxicosis factitia
0.000 0.288 0.712
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.288 0.712
E10.7 With multiple complications
0.000 0.290 0.709
E12 Malnutrition-related diabetes mellitus
0.000 0.291 0.709
E15 Nondiabetic hypoglycaemic coma
0.000 0.296 0.704
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.296 0.704
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.296 0.704
E16.4 Abnormal secretion of gastrin
0.000 0.296 0.704
E16.3 Increased secretion of glucagon
0.000 0.296 0.704
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.297 0.703
E00 Congenital iodine-deficiency syndrome
0.000 0.297 0.703
E10.6 With other specified complications
0.000 0.306 0.694
E13.9 Without complications
0.000 0.308 0.692
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.313 0.687
E10.0 With coma
0.000 0.315 0.685
E14.1 With ketoacidosis
0.000 0.353 0.647
E14.8 With unspecified complications
0.000 0.356 0.644
E40-E46 Malnutrition
0.000 0.365 0.635
E14.6 With other specified complications
0.000 0.370 0.630
E10.5 With peripheral circulatory complications
0.000 0.388 0.612
E14.4 With neurological complications
0.000 0.411 0.588
E14.7 With multiple complications
0.000 0.414 0.586
E14.0 With coma
0.000 0.414 0.586
E07 Other disorders of thyroid
0.000 0.420 0.580
E13.8 With unspecified complications
0.000 0.421 0.579
E13.7 With multiple complications
0.000 0.421 0.579
E13.6 With other specified complications
0.000 0.421 0.579
E13.5 With peripheral circulatory complications
0.000 0.421 0.579
E13.4 With neurological complications
0.000 0.421 0.579
E13.2 With renal complications
0.000 0.421 0.579
E13.1 With ketoacidosis
0.000 0.421 0.579
E13.0 With coma
0.000 0.421 0.579
E13.3 With ophthalmic complications
0.000 0.449 0.551
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.453 0.547
E14.2 Withrenal complications
0.000 0.453 0.546
E06 Thyroiditis
0.000 0.463 0.536
E14.5 With peripheral circulatory complications
0.000 0.485 0.515
E12.9 Without complications
0.000 0.491 0.508
E12.8 With unspecified complications
0.000 0.491 0.508
E12.7 With multiple complications
0.000 0.491 0.508
E12.6 With other specified complications
0.000 0.491 0.508
E12.5 With peripheral circulatory complications
0.000 0.491 0.508
E12.4 With neurological complications
0.000 0.491 0.508
E12.3 With ophthalmic complications
0.000 0.491 0.508
E12.2 With renal complications
0.000 0.491 0.508
E12.1 With ketoacidosis
0.000 0.491 0.508
E12.0 With coma
0.000 0.491 0.508
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.496 0.504
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.496 0.504
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.496 0.504
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.496 0.504
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.496 0.504
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.496 0.504
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.496 0.504
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.496 0.504
E10.8 With unspecified complications
0.001 0.530 0.469
K90 Intestinal malabsorption
0.000 0.533 0.466
E07.8 Other specified disorders of thyroid
0.000 0.536 0.464
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.544 0.455
E45 Retarded development following protein-energy malnutrition
0.000 0.544 0.455
E43 Unspecified severe protein-energy malnutrition
0.000 0.544 0.455
E42 Marasmic kwashiorkor
0.000 0.544 0.455
E41 Nutritional marasmus
0.000 0.544 0.455
E40 Kwashiorkor
0.000 0.544 0.455
E03 Other hypothyroidism
0.000 0.568 0.432
E06.9 Thyroiditis, unspecified
0.000 0.577 0.423
E07.1 Dyshormogenetic goitre
0.000 0.584 0.416
E07.0 Hypersecretion of calcitonin
0.000 0.584 0.416
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.599 0.401
E06.1 Subacute thyroiditis
0.000 0.601 0.398
E46 Unspecified protein-energy malnutrition
0.000 0.614 0.386
E06.4 Drug-induced thyroiditis
0.000 0.615 0.385
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.615 0.385
E06.0 Acute thyroiditis
0.000 0.615 0.385
E06.5 Other chronic thyroiditis
0.000 0.621 0.378
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.001 0.656 0.343
E83 Disorders of mineral metabolism
0.335 0.665 0.001
K90.3 Pancreatic steatorrhoea
0.000 0.665 0.335
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.665 0.335
K90.1 Tropical sprue
0.000 0.665 0.335
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.669 0.331
E44.1 Mild protein-energy malnutrition
0.000 0.673 0.327
E44.0 Moderate protein-energy malnutrition
0.000 0.673 0.327
E65-E68 Obesity and other hyperalimentation
0.000 0.678 0.322
E50-E64 Other nutritional deficiencies
0.000 0.679 0.321
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.681 0.319
E03.5 Myxoedema coma
0.000 0.690 0.310
E03.4 Atrophy of thyroid (acquired)
0.000 0.690 0.310
E03.3 Postinfectious hypothyroidism
0.000 0.690 0.310
K90.8 Other intestinal malabsorption
0.000 0.692 0.308
E83.3 Disorders of phosphorus metabolism
0.305 0.694 0.000
E03.1 Congenital hypothyroidism without goitre
0.000 0.707 0.293
K90.9 Intestinal malabsorption, unspecified
0.000 0.726 0.274
E03.8 Other specified hypothyroidism
0.000 0.726 0.274
E83.9 Disorder of mineral metabolism, unspecified
0.242 0.757 0.000
E83.8 Other disorders of mineral metabolism
0.240 0.759 0.001
E83.2 Disorders of zinc metabolism
0.240 0.759 0.001
E83.0 Disorders of copper metabolism
0.240 0.759 0.001
E51 Thiamine deficiency
0.000 0.761 0.239
E14.9 Without complications
0.000 0.767 0.233
E67 Other hyperalimentation
0.000 0.769 0.231
E68 Sequelae of hyperalimentation
0.000 0.769 0.231
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.769 0.230
E63 Other nutritional deficiencies
0.000 0.769 0.230
E50 Vitamin A deficiency
0.000 0.769 0.230
E60 Dietary zinc deficiency
0.000 0.769 0.230
E59 Dietary selenium deficiency
0.000 0.769 0.230
E54 Ascorbic acid deficiency
0.000 0.769 0.230
E52 Niacin deficiency [pellagra]
0.000 0.769 0.230
E56 Other vitamin deficiencies
0.000 0.785 0.215
E58 Dietary calcium deficiency
0.000 0.795 0.205
E83.4 Disorders of magnesium metabolism
0.199 0.801 0.000
E61 Deficiency of other nutrient elements
0.000 0.807 0.192
E51.2 Wernicke's encephalopathy
0.000 0.820 0.180
E65 Localised adiposity
0.000 0.822 0.178
E07.9 Disorder of thyroid, unspecified
0.000 0.824 0.176
E53 Deficiency of other B group vitamins
0.000 0.825 0.175
E11 Non-insulin-dependent diabetes mellitus
0.000 0.828 0.172
E51.9 Thiamine deficiency, unspecified
0.000 0.828 0.171
E51.8 Other manifestations of thiamine deficiency
0.000 0.828 0.171
E51.1 Beriberi
0.000 0.828 0.171
E55 Vitamin D deficiency
0.000 0.832 0.168
E67.8 Other specified hyperalimentation
0.000 0.834 0.165
E67.3 Hypervitaminosis D
0.000 0.834 0.165
E67.2 Megavitamin-B6 syndrome
0.000 0.834 0.165
E67.1 Hypercarotenaemia
0.000 0.834 0.165
E67.0 Hypervitaminosis A
0.000 0.834 0.165
E50.9 Vitamin A deficiency, unspecified
0.000 0.834 0.165
E50.8 Other manifestations of vitamin A deficiency
0.000 0.834 0.165
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.834 0.165
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.834 0.165
E50.5 Vitamin A deficiency with night blindness
0.000 0.834 0.165
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.834 0.165
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.834 0.165
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.834 0.165
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.834 0.165
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.834 0.165
E63.9 Nutritional deficiency, unspecified
0.000 0.834 0.165
E63.8 Other specified nutritional deficiencies
0.000 0.834 0.165
E63.1 Imbalance of constituents of food intake
0.000 0.834 0.165
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.834 0.165
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.834 0.165
E64.8 Sequelae of other nutritional deficiencies
0.000 0.834 0.165
E64.3 Sequelae of rickets
0.000 0.834 0.165
E64.2 Sequelae of vitamin C deficiency
0.000 0.834 0.165
E64.1 Sequelae of vitamin A deficiency
0.000 0.834 0.165
E64.0 Sequelae of protein-energy malnutrition
0.000 0.834 0.165
I83 Varicose veins of lower extremities
0.162 0.838 0.000
E11.6 With other specified complications
0.000 0.840 0.160
E56.9 Vitamin deficiency, unspecified
0.000 0.845 0.154
E56.8 Deficiency of other vitamins
0.000 0.845 0.154
E56.0 Deficiency of vitamin E
0.000 0.845 0.154
E56.1 Deficiency of vitamin K
0.000 0.861 0.139
E61.9 Deficiency of nutrient element, unspecified
0.000 0.862 0.138
E61.8 Deficiency of other specified nutrient elements
0.000 0.862 0.138
E61.7 Deficiency of multiple nutrient elements
0.000 0.862 0.138
E61.6 Vanadium deficiency
0.000 0.862 0.138
E61.5 Molybdenum deficiency
0.000 0.862 0.138
E61.4 Chromium deficiency
0.000 0.862 0.138
E61.3 Manganese deficiency
0.000 0.862 0.138
E61.0 Copper deficiency
0.000 0.862 0.138
E11.1 With ketoacidosis
0.000 0.864 0.136
E53.9 Vitamin B deficiency, unspecified
0.000 0.870 0.130
E53.1 Pyridoxine deficiency
0.000 0.874 0.126
E53.0 Riboflavin deficiency
0.000 0.874 0.126
E61.1 Iron deficiency
0.000 0.874 0.126
E11.0 With coma
0.000 0.875 0.125
E11.7 With multiple complications
0.000 0.876 0.124
E55.0 Rickets, active
0.000 0.879 0.121
E20-E35 Disorders of other endocrine glands
0.000 0.880 0.120
I83.2 Varicose veins of lower extremities with both ulcer and inflammation
0.118 0.882 0.000
E61.2 Magnesium deficiency
0.000 0.882 0.117
E11.8 With unspecified complications
0.000 0.892 0.108
I83.0 Varicose veins of lower extremities with ulcer
0.102 0.898 0.000
E11.2 With renal complications
0.000 0.899 0.101
E24 Cushing's syndrome
0.000 0.900 0.100
E06.3 Autoimmune thyroiditis
0.002 0.912 0.086
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.913 0.087
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.914 0.086
E32 Diseases of thymus
0.000 0.914 0.086
E30 Disorders of puberty, not elsewhere classified
0.000 0.914 0.086
E20 Hypoparathyroidism
0.000 0.914 0.086
E25 Adrenogenital disorders
0.000 0.916 0.084
E03.9 Hypothyroidism, unspecified
0.000 0.917 0.083
E29 Testicular dysfunction
0.000 0.918 0.082
E31 Polyglandular dysfunction
0.000 0.919 0.081
E24.2 Drug-induced Cushing's syndrome
0.000 0.921 0.079
E21.3 Hyperparathyroidism, unspecified
0.000 0.921 0.079
E22 Hyperfunction of pituitary gland
0.000 0.923 0.077
E24.0 Pituitary-dependent Cushing's disease
0.000 0.923 0.077
E24.9 Cushing's syndrome, unspecified
0.000 0.924 0.076
E24.8 Other Cushing's syndrome
0.000 0.925 0.075
E34 Other endocrine disorders
0.000 0.927 0.073
E28 Ovarian dysfunction
0.000 0.927 0.073
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.928 0.072
E24.3 Ectopic ACTH syndrome
0.000 0.928 0.072
E24.1 Nelson's syndrome
0.000 0.928 0.072
E11.5 With peripheral circulatory complications
0.000 0.932 0.068
C19 Malignant neoplasm of rectosigmoid junction
0.000 0.933 0.067
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.935 0.065
E21.4 Other specified disorders of parathyroid gland
0.000 0.937 0.062
E30.9 Disorder of puberty, unspecified
0.000 0.938 0.062
E30.8 Other disorders of puberty
0.000 0.938 0.062
E30.1 Precocious puberty
0.000 0.938 0.062
E30.0 Delayed puberty
0.000 0.938 0.062
E32.9 Disease of thymus, unspecified
0.000 0.938 0.062
E32.8 Other diseases of thymus
0.000 0.938 0.062
E32.1 Abscess of thymus
0.000 0.938 0.062
E32.0 Persistent hyperplasia of thymus
0.000 0.938 0.062
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.938 0.062
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.938 0.062
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.938 0.062
E53.8 Deficiency of other specified B group vitamins
0.000 0.938 0.062
E20.8 Other hypoparathyroidism
0.000 0.938 0.061
E20.1 Pseudohypoparathyroidism
0.000 0.938 0.061
E20.0 Idiopathic hypoparathyroidism
0.000 0.938 0.061
E21.2 Other hyperparathyroidism
0.000 0.938 0.062
E20.9 Hypoparathyroidism, unspecified
0.000 0.939 0.061
E25.9 Adrenogenital disorder, unspecified
0.000 0.939 0.061
E25.8 Other adrenogenital disorders
0.000 0.939 0.061
E26 Hyperaldosteronism
0.000 0.940 0.060
E11.3 With ophthalmic complications
0.000 0.940 0.060
E22.1 Hyperprolactinaemia
0.000 0.941 0.059
E29.9 Testicular dysfunction, unspecified
0.000 0.941 0.059
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.941 0.059
E29.8 Other testicular dysfunction
0.000 0.941 0.059
E29.0 Testicular hyperfunction
0.000 0.941 0.059
E31.9 Polyglandular dysfunction, unspecified
0.000 0.942 0.058
E31.8 Other polyglandular dysfunction
0.000 0.942 0.058
E31.1 Polyglandular hyperfunction
0.000 0.942 0.058
E55.9 Vitamin D deficiency, unspecified
0.000 0.942 0.058
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.944 0.056
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.944 0.056
E22.8 Other hyperfunction of pituitary gland
0.000 0.944 0.056
E11.4 With neurological complications
0.000 0.945 0.055
E34.3 Short stature, not elsewhere classified
0.000 0.945 0.055
E29.1 Testicular hypofunction
0.000 0.945 0.055
E31.0 Autoimmune polyglandular failure
0.000 0.946 0.053
E34.5 Androgen resistance syndrome
0.000 0.947 0.053
E34.4 Constitutional tall stature
0.000 0.947 0.053
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.947 0.053
E34.1 Other hypersecretion of intestinal hormones
0.000 0.947 0.053
E28.9 Ovarian dysfunction, unspecified
0.000 0.947 0.052
E28.8 Other ovarian dysfunction
0.000 0.947 0.052
E28.1 Androgen excess
0.000 0.947 0.052
E28.0 Oestrogen excess
0.000 0.947 0.052
E34.9 Endocrine disorder, unspecified
0.000 0.948 0.052
E23 Hypofunction and other disorders of pituitary gland
0.000 0.948 0.052
E28.2 Polycystic ovarian syndrome
0.000 0.949 0.050
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.950 0.049
C20 Malignant neoplasm of rectum
0.000 0.951 0.049
E34.8 Other specified endocrine disorders
0.000 0.951 0.049
I83.1 Varicose veins of lower extremities with inflammation
0.048 0.952 0.000
E04 Other non-toxic goitre
0.002 0.953 0.045
C15-C26 Malignant neoplasms of digestive organs
0.000 0.956 0.044
E26.8 Other hyperaldosteronism
0.000 0.956 0.043
E26.1 Secondary hyperaldosteronism
0.000 0.956 0.043
E34.0 Carcinoid syndrome
0.000 0.957 0.043
C15 Malignant neoplasm of oesophagus
0.000 0.957 0.043
E23.7 Disorder of pituitary gland, unspecified
0.000 0.958 0.042
E28.3 Primary ovarian failure
0.000 0.958 0.042
C15.4 Middle third of oesophagus
0.000 0.959 0.041
E11.9 Without complications
0.000 0.960 0.040
E22.0 Acromegaly and pituitary gigantism
0.000 0.960 0.040
E21.0 Primary hyperparathyroidism
0.000 0.960 0.040
E26.9 Hyperaldosteronism, unspecified
0.000 0.961 0.039
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.963 0.037
E23.1 Drug-induced hypopituitarism
0.000 0.963 0.037
C25 Malignant neoplasm of pancreas
0.000 0.964 0.036
C15.5 Lower third of oesophagus
0.000 0.964 0.036
C17 Malignant neoplasm of small intestine
0.000 0.965 0.035
C17.0 Duodenum
0.000 0.966 0.034
E04.8 Other specified non-toxic goitre
0.001 0.966 0.032
C15.3 Upper third of oesophagus
0.000 0.967 0.033
C15.0 Cervical part of oesophagus
0.000 0.968 0.032
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.000 0.968 0.031
C15.8 Overlapping lesion of oesophagus
0.000 0.969 0.031
C15.2 Abdominal part of oesophagus
0.000 0.969 0.031
C15.1 Thoracic part of oesophagus
0.000 0.969 0.031
E23.6 Other disorders of pituitary gland
0.000 0.969 0.031
C25.3 Pancreatic duct
0.000 0.969 0.030
C25.1 Body of pancreas
0.000 0.970 0.030
C15.9 Oesophagus, unspecified
0.000 0.970 0.030
C25.8 Overlapping lesion of pancreas
0.000 0.971 0.029
E23.2 Diabetes insipidus
0.000 0.971 0.029
M72.04 Palmar fascial fibromatosis [Dupuytren]-Hand
0.000 0.971 0.029
K90-K93 Other diseases of the digestive system
0.000 0.972 0.028
C25.2 Tail of pancreas
0.000 0.972 0.028
C24.0 Extrahepatic bile duct
0.000 0.972 0.027
C25.4 Endocrine pancreas
0.000 0.973 0.027
E26.0 Primary hyperaldosteronism
0.001 0.974 0.026
Z71.8 Other specified counselling
0.026 0.974 0.000
C17.8 Overlapping lesion of small intestine
0.000 0.975 0.025
C17.3 Meckel's diverticulum
0.000 0.975 0.025
C17.1 Jejunum
0.000 0.975 0.025
E04.0 Non-toxic diffuse goitre
0.001 0.976 0.023
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.000 0.976 0.023
C25.7 Other parts of pancreas
0.000 0.977 0.023
C24.8 Overlapping lesion of biliary tract
0.000 0.977 0.023
C25.9 Pancreas, unspecified
0.000 0.977 0.023
C24.9 Biliary tract, unspecified
0.000 0.977 0.022
K14.8 Other diseases of tongue
0.000 0.978 0.022
Z90.5 Acquired absence of kidney
0.022 0.978 0.000
E27 Other disorders of adrenal gland
0.000 0.979 0.021
E66 Obesity
0.000 0.979 0.021
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.980 0.020
C26 Malignant neoplasm of other and ill-defined digestive organs
0.000 0.980 0.020
I73.9 Peripheral vascular disease, unspecified
0.000 0.980 0.020
C21 Malignant neoplasm of anus and anal canal
0.000 0.981 0.019
C22.9 Liver, unspecified
0.000 0.981 0.019
C23 Malignant neoplasm of gallbladder
0.000 0.981 0.018
C25.0 Head of pancreas
0.000 0.981 0.019
I73.0 Raynaud's syndrome
0.000 0.981 0.019
I73 Other peripheral vascular diseases
0.000 0.982 0.018
E23.0 Hypopituitarism
0.000 0.982 0.018
E83.5 Disorders of calcium metabolism
0.017 0.982 0.000
C22.7 Other specified carcinomas of liver
0.000 0.983 0.017
C22.4 Other sarcomas of liver
0.000 0.983 0.017
C22.3 Angiosarcoma of liver
0.000 0.983 0.017
C22.2 Hepatoblastoma
0.000 0.983 0.017
C17.9 Small intestine, unspecified
0.000 0.983 0.017
E70-E90 Metabolic disorders
0.008 0.984 0.008
C17.2 Ileum
0.000 0.984 0.016
C22.1 Intrahepatic bile duct carcinoma
0.000 0.984 0.016
E27.5 Adrenomedullary hyperfunction
0.000 0.984 0.015
E27.0 Other adrenocortical overactivity
0.000 0.984 0.015
E27.1 Primary adrenocortical insufficiency
0.000 0.984 0.015
E66.1 Drug-induced obesity
0.000 0.985 0.015
I73.8 Other specified peripheral vascular diseases
0.000 0.985 0.015
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.000 0.985 0.015
K93.1 Megacolon in Chagas' disease
0.000 0.985 0.015
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.000 0.985 0.015
C26.8 Overlapping lesion of digestive system
0.000 0.985 0.015
C26.1 Spleen
0.000 0.985 0.015
S02.40 Fracture of malar and maxillary bones (closed)
0.000 0.985 0.015
C21.2 Cloacogenic zone
0.000 0.986 0.014
C18.9 Colon, unspecified
0.000 0.986 0.014
H40.2 Primary angle-closure glaucoma
0.013 0.987 0.000
C18 Malignant neoplasm of colon
0.000 0.987 0.013
E27.9 Disorder of adrenal gland, unspecified
0.000 0.987 0.013
C18.1 Appendix
0.000 0.987 0.013
C24.1 Ampulla of Vater
0.001 0.987 0.012
S02.4 Fracture of malar and maxillary bones
0.000 0.987 0.013
C21.8 Overlapping lesion of rectum, anus and anal canal
0.000 0.987 0.012
R31 Unspecified haematuria
0.012 0.988 0.000
I73.1 Thromboangiitis obliterans [Buerger]
0.000 0.988 0.012
C21.1 Anal canal
0.000 0.988 0.012
E77 Disorders of glycoprotein metabolism
0.006 0.988 0.006
E76 Disorders of glycosaminoglycan metabolism
0.006 0.988 0.006
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.006 0.988 0.006
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.006 0.988 0.006
E70 Disorders of aromatic amino-acid metabolism
0.006 0.988 0.005
E72 Other disorders of amino-acid metabolism
0.007 0.988 0.005
E27.2 Addisonian crisis
0.000 0.988 0.011
E79 Disorders of purine and pyrimidine metabolism
0.007 0.988 0.005
E84 Cystic fibrosis
0.006 0.988 0.006
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.005 0.988 0.006
E66.0 Obesity due to excess calories
0.000 0.988 0.011
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.988 0.011
S02 Fracture of skull and facial bones
0.000 0.989 0.011
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.989 0.011
E74 Other disorders of carbohydrate metabolism
0.005 0.989 0.006
M45.X9 Ankylosing spondylitis (Site unspecified)
0.011 0.989 0.000
I77 Other disorders of arteries and arterioles
0.000 0.989 0.011
I77.6 Arteritis, unspecified
0.000 0.989 0.011
E73 Lactose intolerance
0.005 0.989 0.006
E85 Amyloidosis
0.006 0.989 0.005
C26.9 Ill-defined sites within the digestive system
0.000 0.989 0.010
S02.0 Fracture of vault of skull
0.000 0.989 0.011
E27.8 Other specified disorders of adrenal gland
0.000 0.990 0.010
M72.0 Palmar fascial fibromatosis [Dupuytren]
0.000 0.990 0.010
S02.00 Fracture of vault of skull (closed)
0.000 0.990 0.010
C18.8 Overlapping lesion of colon
0.000 0.990 0.010
C26.0 Intestinal tract, part unspecified
0.000 0.990 0.010
S02.3 Fracture of orbital floor
0.000 0.990 0.010
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.990 0.010
I77.9 Disorder of arteries and arterioles, unspecified
0.000 0.990 0.010
S02.8 Fractures of other skull and facial bones
0.000 0.990 0.010
I77.8 Other specified disorders of arteries and arterioles
0.000 0.990 0.010
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.990 0.010
S02.6 Fracture of mandible
0.000 0.991 0.009
E04.9 Non-toxic goitre, unspecified
0.001 0.991 0.009
C21.0 Anus, unspecified
0.000 0.991 0.009
S02.30 Fracture of orbital floor (closed)
0.000 0.991 0.009
I77.1 Stricture of artery
0.000 0.991 0.009
E80 Disorders of porphyrin and bilirubin metabolism
0.006 0.991 0.003
S02.7 Multiple fractures involving skull and facial bones
0.000 0.991 0.009
S02.5 Fracture of tooth
0.000 0.991 0.009
S02.80 Fractures of other skull and facial bones (closed)
0.000 0.991 0.009
E88 Other metabolic disorders
0.004 0.991 0.005
E71.3 Disorders of fatty-acid metabolism
0.005 0.991 0.004
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.005 0.991 0.004
E71.1 Other disorders of branched-chain amino-acid metabolism
0.005 0.991 0.004
E71.0 Maple-syrup-urine disease
0.005 0.991 0.004
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.005 0.991 0.004
E76.8 Other disorders of glucosaminoglycan metabolism
0.005 0.991 0.004
E76.3 Mucopolysaccharidosis, unspecified
0.005 0.991 0.004
E76.2 Other mucopolysaccharidoses
0.005 0.991 0.004
E76.1 Mucopolysaccharidosis, type II
0.005 0.991 0.004
E76.0 Mucopolysaccharidosis, type I
0.005 0.991 0.004
E77.9 Disorder of glycoprotein metabolism, unspecified
0.005 0.991 0.004
E77.8 Other disorders of glycoprotein metabolism
0.005 0.991 0.004
E77.1 Defects in glycoprotein degradation
0.005 0.991 0.004
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.005 0.991 0.004
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.005 0.991 0.004
E70.8 Other disorders of aromatic amino-acid metabolism
0.005 0.991 0.004
E70.2 Disorders of tyrosine metabolism
0.005 0.991 0.004
E70.1 Other hyperphenylalaninaemias
0.005 0.991 0.004
E70.0 Classical phenylketonuria
0.005 0.991 0.004
E72.9 Disorder of amino-acid metabolism, unspecified
0.005 0.991 0.004
E72.8 Other specified disorders of amino-acid metabolism
0.005 0.991 0.004
E72.5 Disorders of glycine metabolism
0.005 0.991 0.004
E72.4 Disorders of ornithine metabolism
0.005 0.991 0.004
E72.3 Disorders of lysine and hydroxylysine metabolism
0.005 0.991 0.004
E72.2 Disorders of urea cycle metabolism
0.005 0.991 0.004
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.005 0.991 0.003
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.005 0.991 0.004
E79.8 Other disorders of purine and pyrimidine metabolism
0.005 0.991 0.004
E79.1 Lesch-Nyhan syndrome
0.005 0.991 0.004
E70.3 Albinism
0.005 0.991 0.004
E84.8 Cystic fibrosis with other manifestations
0.005 0.991 0.004
E84.1 Cystic fibrosis with intestinal manifestations
0.005 0.991 0.004
E75.6 Lipid storage disorder, unspecified
0.004 0.991 0.005
E75.4 Neuronal ceroid lipofuscinosis
0.004 0.991 0.005
E75.3 Sphingolipidosis, unspecified
0.004 0.991 0.005
E75.1 Other gangliosidosis
0.004 0.991 0.005
E75.0 GM2 gangliosidosis
0.004 0.991 0.005
E72.0 Disorders of amino-acid transport
0.005 0.991 0.004
I74.5 Embolism and thrombosis of iliac artery
0.000 0.991 0.009
I77.3 Arterial fibromuscular dysplasia
0.000 0.991 0.008
E84.0 Cystic fibrosis with pulmonary manifestations
0.004 0.991 0.004
S02.41 Fracture of malar and maxillary bones (open)
0.000 0.992 0.008
E75.2 Other sphingolipidosis
0.004 0.992 0.005
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.005 0.992 0.003
E75.5 Other lipid storage disorders
0.003 0.992 0.005
E84.9 Cystic fibrosis, unspecified
0.005 0.992 0.004
E74.9 Disorder of carbohydrate metabolism, unspecified
0.004 0.992 0.004
E74.8 Other specified disorders of carbohydrate metabolism
0.004 0.992 0.004
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.004 0.992 0.004
E74.2 Disorders of galactose metabolism
0.004 0.992 0.004
E74.1 Disorders of fructose metabolism
0.004 0.992 0.004
E74.0 Glycogen storage disease
0.004 0.992 0.004
I77.2 Rupture of artery
0.000 0.992 0.008
I77.5 Necrosis of artery
0.000 0.992 0.008
I77.4 Coeliac artery compression syndrome
0.000 0.992 0.008
I74 Arterial embolism and thrombosis
0.000 0.992 0.008
E73.8 Other lactose intolerance
0.004 0.992 0.004
E73.1 Secondary lactase deficiency
0.004 0.992 0.004
E73.0 Congenital lactase deficiency
0.004 0.992 0.004
E85.8 Other amyloidosis
0.004 0.992 0.004
E85.2 Heredofamilial amyloidosis, unspecified
0.004 0.992 0.004
E85.1 Neuropathic heredofamilial amyloidosis
0.004 0.992 0.004
E85.0 Nonneuropathic heredofamilial amyloidosis
0.004 0.992 0.004
S02.60 Fracture of mandible (closed)
0.000 0.992 0.008
M72.00 Palmar fascial fibromatosis [Dupuytren]-Mult sites
0.000 0.992 0.008
S02.01 Fracture of vault of skull (open)
0.000 0.992 0.008
S02.9 Fracture of skull and facial bones, part unspecified
0.000 0.992 0.008
M72.08 Palmar fascial fibromatosis [Dupuytren]-Other
0.000 0.992 0.008
M72.06 Palmar fascial fibromatosis [Dupuytren]-Lower Leg
0.000 0.992 0.008
M72.05 Palmar fascial fibromatosis [Dupuytren]-Pelvic/Thigh
0.000 0.992 0.008
M72.03 Palmar fascial fibromatosis [Dupuytren]-Forearm
0.000 0.992 0.008
M72.02 Palmar fascial fibromatosis [Dupuytren]-Upper arm
0.000 0.992 0.008
M72.01 Palmar fascial fibromatosis [Dupuytren]-Shldr region
0.000 0.992 0.008
E85.3 Secondary systemic amyloidosis
0.004 0.992 0.004
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.007 0.992 0.001
E74.3 Other disorders of intestinal carbohydrate absorption
0.003 0.992 0.004
E85.9 Amyloidosis, unspecified
0.005 0.992 0.002
S02.31 Fracture of orbital floor (open)
0.000 0.992 0.007
S02.81 Fractures of other skull and facial bones (open)
0.000 0.993 0.007
C22.0 Liver cell carcinoma
0.000 0.993 0.007
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.993 0.007
S02.70 Multiple fractures involving skull and facial bones (closed)
0.000 0.993 0.007
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.007 0.993 0.000
K14 Diseases of tongue
0.000 0.993 0.007
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.000 0.993 0.007

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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