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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs10490871
log Bayes Factor = 6.36422
Chromosome 3   position 35,667,761  (GRCh37) Explore rs10490871 on Ensembl!
Variant rs10490871 is part of Cluster X0250

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I35 Nonrheumatic aortic valve disorders
1.000 0.000 0.000
F10 Mental and behavioural disorders due to use of alcohol
1.000 0.000 0.000
I30-I52 Other forms of heart disease
1.000 0.000 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.999 0.001 0.000
Chapter V Mental and behavioural disorders
0.999 0.001 0.000
I51 Complications and ill-defined descriptions of heart disease
0.999 0.001 0.000
I35.1 Aortic (valve) insufficiency
0.998 0.002 0.000
I51.7 Cardiomegaly
0.997 0.003 0.000
I50 Heart failure
0.996 0.004 0.000
H65-H75 Diseases of middle ear and mastoid
0.996 0.004 0.000
Chapter VIII Diseases of the ear and mastoid process
0.996 0.004 0.000
Chapter IX Diseases of the circulatory system
0.996 0.004 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.995 0.005 0.000
F10.1 Harmful use
0.995 0.005 0.000
# Top node
0.995 0.005 0.000
I35.0 Aortic (valve) stenosis
0.994 0.006 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.993 0.007 0.000
I50.1 Left ventricular failure
0.993 0.007 0.000
I05-I09 Chronic rheumatic heart diseases
0.990 0.010 0.000
Q23 Congenital malformations of aortic and mitral valves
0.986 0.014 0.000
H72 Perforation of tympanic membrane
0.986 0.014 0.000
H72.9 Perforation of tympanic membrane, unspecified
0.984 0.016 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.984 0.016 0.000
F10.3 Withdrawal state
0.981 0.019 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.977 0.023 0.000
H65 Nonsuppurative otitis media
0.973 0.027 0.000
F10.0 Acute intoxication
0.969 0.031 0.000
H90-H95 Other disorders of ear
0.965 0.035 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.963 0.037 0.000
Q23.1 Congenital insufficiency of aortic valve
0.961 0.039 0.000
I08 Multiple valve diseases
0.958 0.042 0.000
F43 Reaction to severe stress, and adjustment disorders
0.949 0.051 0.000
H65.3 Chronic mucoid otitis media
0.946 0.054 0.000
F99-F99 Unspecified mental disorder
0.938 0.062 0.000
I05 Rheumatic mitral valve diseases
0.936 0.064 0.000
I51.9 Heart disease, unspecified
0.932 0.068 0.000
Q27 Other congenital malformations of peripheral vascular system
0.920 0.080 0.000
F44 Dissociative [conversion] disorders
0.911 0.089 0.000
I51.4 Myocarditis, unspecified
0.910 0.090 0.000
H91 Other hearing loss
0.906 0.094 0.000
F40 Phobic anxiety disorders
0.898 0.102 0.000
I08.2 Disorders of both aortic and tricuspid valves
0.897 0.103 0.000
F99 Mental disorder, not otherwise specified
0.895 0.105 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.892 0.108 0.000
Q25 Congenital malformations of great arteries
0.884 0.116 0.000
Q38 Other congenital malformations of tongue, mouth and pharynx
0.883 0.117 0.000
Q23.0 Congenital stenosis of aortic valve
0.880 0.120 0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.876 0.124 0.000
I10-I15 Hypertensive diseases
0.871 0.129 0.000
H91.9 Hearing loss, unspecified
0.869 0.131 0.000
Q27.3 Peripheral arteriovenous malformation
0.864 0.136 0.000
H65.4 Other chronic nonsuppurative otitis media
0.862 0.138 0.000
I05.2 Mitral stenosis with insufficiency
0.861 0.139 0.000
Q00-Q07 Congenital malformations of the nervous system
0.855 0.145 0.000
I08.0 Disorders of both mitral and aortic valves
0.852 0.148 0.000
F43.0 Acute stress reaction
0.851 0.149 0.000
I36 Nonrheumatic tricuspid valve disorders
0.849 0.151 0.000
F45 Somatoform disorders
0.843 0.157 0.000
Q50-Q56 Congenital malformations of genital organs
0.842 0.158 0.000
F60-F69 Disorders of adult personality and behaviour
0.841 0.159 0.000
Q23.3 Congenital mitral insufficiency
0.838 0.162 0.000
F43.2 Adjustment disorders
0.837 0.163 0.000
I05.9 Mitral valve disease, unspecified
0.832 0.168 0.000
H90 Conductive and sensorineural hearing loss
0.829 0.171 0.000
F11 Mental and behavioural disorders due to use of opioids
0.827 0.173 0.000
F44.4 Dissociative motor disorders
0.823 0.177 0.000
F43.1 Posttraumatic stress disorder
0.821 0.179 0.000
Q80-Q89 Other congenital malformations
0.818 0.182 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.812 0.188 0.000
H65.2 Chronic serous otitis media
0.805 0.195 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.803 0.197 0.000
H73 Other disorders of tympanic membrane
0.801 0.199 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.801 0.199 0.000
H70 Mastoiditis and related conditions
0.801 0.199 0.000
I11 Hypertensive heart disease
0.799 0.201 0.000
F40.2 Specific (isolated) phobias
0.797 0.203 0.000
Chapter VII Diseases of the eye and adnexa
0.795 0.205 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.794 0.206 0.000
F10.5 Psychotic disorder
0.794 0.206 0.000
Q43 Other congenital malformations of intestine
0.793 0.207 0.000
Q39 Congenital malformations of oesophagus
0.793 0.207 0.000
H91.3 Deaf mutism, not elsewhere classified
0.791 0.209 0.000
H74 Other disorders of middle ear and mastoid
0.790 0.210 0.000
Q40 Other congenital malformations of upper alimentary tract
0.788 0.211 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.788 0.212 0.000
H18 Other disorders of cornea
0.788 0.212 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.785 0.215 0.000
H21 Other disorders of iris and ciliary body
0.783 0.217 0.000
I09 Other rheumatic heart diseases
0.782 0.218 0.000
H90.2 Conductive hearing loss, unspecified
0.781 0.219 0.000
F10.7 Residual and late-onset psychotic disorder
0.777 0.222 0.000
F10.9 Unspecified mental and behavioural disorder
0.774 0.226 0.000
I50.0 Congestive heart failure
0.772 0.228 0.000
Q38.1 Ankyloglossia
0.772 0.228 0.000
F44.9 Dissociative [conversion] disorder, unspecified
0.772 0.228 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.766 0.234 0.000
M80-M85 Disorders of bone density and structure
0.765 0.235 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.763 0.236 0.000
F10.6 Amnesic syndrome
0.763 0.237 0.000
I06 Rheumatic aortic valve diseases
0.762 0.238 0.000
Q05 Spina bifida
0.762 0.238 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.758 0.242 0.000
Q22 Congenital malformations of pulmonary and tricuspid valves
0.757 0.243 0.000
F40.0 Agoraphobia
0.754 0.246 0.000
Q28 Other congenital malformations of circulatory system
0.754 0.246 0.000
Q25.1 Coarctation of aorta
0.750 0.249 0.000
H66 Suppurative and unspecified otitis media
0.749 0.251 0.000
Q52 Other congenital malformations of female genitalia
0.748 0.252 0.000
Q27.9 Congenital malformation of peripheral vascular system, unspecified
0.746 0.253 0.000
I36.1 Nonrheumatic tricuspid (valve) insufficiency
0.742 0.258 0.000
I11.9 Hypertensive heart disease without (congestive) heart failure
0.738 0.262 0.000
F61 Mixed and other personality disorders
0.737 0.263 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.736 0.264 0.000
F10.4 Withdrawal state with delirium
0.736 0.264 0.000
F10.8 Other mental and behavioural disorders
0.735 0.265 0.000
H65.1 Other acute nonsuppurative otitis media
0.735 0.265 0.000
I43.1 Cardiomyopathy in metabolic diseases
0.734 0.265 0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified
0.734 0.266 0.000
F45.3 Somatoform autonomic dysfunction
0.731 0.269 0.000
F70-F79 Mental retardation
0.728 0.272 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.728 0.272 0.000
H21.0 Hyphaema
0.723 0.277 0.000
I05.0 Mitral stenosis
0.723 0.277 0.000
H65.0 Acute serous otitis media
0.721 0.279 0.000
I05.8 Other mitral valve diseases
0.721 0.279 0.000
I43.8 Cardiomyopathy in other diseases classified elsewhere
0.720 0.280 0.000
I37 Pulmonary valve disorders
0.719 0.280 0.000
M05-M14 Inflammatory polyarthropathies
0.718 0.282 0.000
I52 Other heart disorders in diseases classified elsewhere
0.717 0.283 0.000
I48 Atrial fibrillation and flutter
0.717 0.283 0.000
I41 Myocarditis in diseases classified elsewhere
0.717 0.283 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.717 0.283 0.000
I32 Pericarditis in diseases classified elsewhere
0.717 0.283 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.717 0.283 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.717 0.283 0.000
I51.5 Myocardial degeneration
0.716 0.284 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.716 0.284 0.000
I40 Acute myocarditis
0.716 0.284 0.000
F44.0 Dissociative amnesia
0.716 0.284 0.000
Q25.0 Patent ductus arteriosus
0.714 0.286 0.000
I10 Essential (primary) hypertension
0.714 0.286 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.714 0.286 0.000
H67 Otitis media in diseases classified elsewhere
0.714 0.286 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.713 0.287 0.000
Q54 Hypospadias
0.713 0.287 0.000
Q26 Congenital malformations of great veins
0.712 0.288 0.000
Q20 Congenital malformations of cardiac chambers and connexions
0.712 0.288 0.000
H71 Cholesteatoma of middle ear
0.711 0.289 0.000
M80 Osteoporosis with pathological fracture
0.711 0.289 0.000
H93 Other disorders of ear, not elsewhere classified
0.710 0.290 0.000
I50.9 Heart failure, unspecified
0.710 0.290 0.000
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere
0.709 0.291 0.000
F11.3 Withdrawal state
0.707 0.293 0.000
Q23.9 Congenital malformation of aortic and mitral valves, unspecified
0.707 0.293 0.000
Q23.8 Other congenital malformations of aortic and mitral valves
0.707 0.293 0.000
Q23.4 Hypoplastic left heart syndrome
0.707 0.293 0.000
Q23.2 Congenital mitral stenosis
0.707 0.293 0.000
F45.0 Somatisation disorder
0.707 0.293 0.000
I51.0 Cardiac septal defect, acquired
0.707 0.293 0.000
M40-M43 Deforming dorsopathies
0.703 0.297 0.000
H92 Otalgia and effusion of ear
0.703 0.297 0.000
H18.5 Hereditary corneal dystrophies
0.703 0.297 0.000
Q05.9 Spina bifida, unspecified
0.702 0.298 0.000
Q38.0 Congenital malformations of lips, not elsewhere classified
0.702 0.298 0.000
I15 Secondary hypertension
0.702 0.298 0.000
I35.9 Aortic valve disorder, unspecified
0.701 0.299 0.000
Q25.4 Other congenital malformations of aorta
0.700 0.300 0.000
H90.3 Sensorineural hearing loss, bilateral
0.698 0.302 0.000
H69 Other disorders of Eustachian tube
0.697 0.302 0.000
M45-M49 Spondylopathies
0.698 0.302 0.000
M82 Osteoporosis in diseases classified elsewhere
0.695 0.305 0.000
H18.6 Keratoconus
0.694 0.306 0.000
Q38.7 Pharyngeal pouch
0.694 0.306 0.000
H94 Other disorders of ear in diseases classified elsewhere
0.692 0.308 0.000
M13 Other arthritis
0.692 0.308 0.000
H16 Keratitis
0.690 0.310 0.000
Q42 Congenital absence, atresia and stenosis of large intestine
0.690 0.310 0.000
Q41 Congenital absence, atresia and stenosis of small intestine
0.690 0.310 0.000
F11.2 Dependence syndrome
0.686 0.314 0.000
Q35-Q37 Cleft lip and cleft palate
0.685 0.315 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.683 0.316 0.000
H68 Eustachian salpingitis and obstruction
0.683 0.317 0.000
H18.1 Bullous keratopathy
0.683 0.317 0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere
0.681 0.319 0.000
F69 Unspecified disorder of adult personality and behaviour
0.681 0.319 0.000
F43.8 Other reactions to severe stress
0.680 0.320 0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver
0.678 0.322 0.000
M00-M03 Infectious arthropathies
0.678 0.322 0.000
F55 Abuse of non-dependence-producing substances
0.678 0.322 0.000
M13.9 Arthritis, unspecified
0.676 0.324 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.675 0.324 0.000
H21.8 Other specified disorders of iris and ciliary body
0.674 0.326 0.000
H90.5 Sensorineural hearing loss, unspecified
0.674 0.326 0.000
M45 Ankylosing spondylitis
0.673 0.327 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.671 0.329 0.000
I00-I02 Acute rheumatic fever
0.671 0.329 0.000
D80-D89 Certain disorders involving the immune mechanism
0.670 0.330 0.000
H74.4 Polyp of middle ear
0.669 0.331 0.000
H72.1 Attic perforation of tympanic membrane
0.667 0.333 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.667 0.333 0.000
Q52.5 Fusion of labia
0.667 0.333 0.000
M41 Scoliosis
0.666 0.334 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.666 0.334 0.000
D80 Immunodeficiency with predominantly antibody defects
0.663 0.337 0.000
H21.2 Degeneration of iris and ciliary body
0.661 0.339 0.000
Q85 Phakomatoses, not elsewhere classified
0.661 0.339 0.000
Q27.4 Congenital phlebectasia
0.659 0.341 0.000
Q27.2 Other congenital malformations of renal artery
0.659 0.341 0.000
Q27.1 Congenital renal artery stenosis
0.659 0.341 0.000
Q27.0 Congenital absence and hypoplasia of umbilical artery
0.659 0.341 0.000
Q39.4 Oesophageal web
0.658 0.342 0.000
Q45 Other congenital malformations of digestive system
0.657 0.343 0.000
M85 Other disorders of bone density and structure
0.656 0.344 0.000
I07 Rheumatic tricuspid valve diseases
0.655 0.345 0.000
I51.6 Cardiovascular disease, unspecified
0.654 0.346 0.000
M13.99 Arthritis, unspecified (Site unspecified)
0.653 0.347 0.000
F44.7 Mixed dissociative [conversion] disorders
0.653 0.347 0.000
F44.6 Dissociative anaesthesia and sensory loss
0.653 0.347 0.000
F44.3 Trance and possession disorders
0.653 0.347 0.000
F44.2 Dissociative stupor
0.653 0.347 0.000
F44.1 Dissociative fugue
0.653 0.347 0.000
Q40.2 Other specified congenital malformations of stomach
0.652 0.348 0.000
F40.8 Other phobic anxiety disorders
0.652 0.348 0.000
H90.0 Conductive hearing loss, bilateral
0.651 0.349 0.000
H91.0 Ototoxic hearing loss
0.649 0.351 0.000
Q38.6 Other congenital malformations of mouth
0.649 0.351 0.000
F44.8 Other dissociative [conversion] disorders
0.649 0.351 0.000
H21.5 Other adhesions and disruptions of iris and ciliary body
0.649 0.351 0.000
H93.8 Other specified disorders of ear
0.647 0.353 0.000
H18.9 Disorder of cornea, unspecified
0.647 0.353 0.000
F25 Schizoaffective disorders
0.645 0.355 0.000
H25-H28 Disorders of lens
0.645 0.355 0.000
M82.1 Osteoporosis in endocrine disorders
0.644 0.356 0.000
F40.1 Social phobias
0.644 0.356 0.000
Q06 Other congenital malformations of spinal cord
0.642 0.357 0.000
M60-M63 Disorders of muscles
0.642 0.358 0.000
Q89 Other congenital malformations, not elsewhere classified
0.641 0.359 0.000
Q83 Congenital malformations of breast
0.641 0.359 0.000
F14.2 Dependence syndrome
0.641 0.359 0.000
I43.2 Cardiomyopathy in nutritional diseases
0.639 0.361 0.000
H16.0 Corneal ulcer
0.639 0.361 0.000
H73.8 Other specified disorders of tympanic membrane
0.638 0.362 0.000
H74.3 Other acquired abnormalities of ear ossicles
0.638 0.362 0.000
Q43.8 Other specified congenital malformations of intestine
0.638 0.362 0.000
H70.9 Mastoiditis, unspecified
0.637 0.363 0.000
H73.0 Acute myringitis
0.636 0.364 0.000
I33 Acute and subacute endocarditis
0.635 0.365 0.000
H18.4 Corneal degeneration
0.635 0.365 0.000
Q25.9 Congenital malformation of great arteries, unspecified
0.634 0.366 0.000
Q25.8 Other congenital malformations of great arteries
0.634 0.366 0.000
Q25.7 Other congenital malformations of pulmonary artery
0.634 0.366 0.000
Q25.5 Atresia of pulmonary artery
0.634 0.366 0.000
Q25.3 Stenosis of aorta
0.634 0.366 0.000
Q25.2 Atresia of aorta
0.634 0.366 0.000
I09.9 Rheumatic heart disease, unspecified
0.634 0.366 0.000
Q38.8 Other congenital malformations of pharynx
0.633 0.367 0.000
Q38.5 Congenital malformations of palate, not elsewhere classified
0.633 0.367 0.000
Q38.4 Congenital malformations of salivary glands and ducts
0.633 0.367 0.000
Q38.3 Other congenital malformations of tongue
0.633 0.367 0.000
Q38.2 Macroglossia
0.633 0.367 0.000
H27 Other disorders of lens
0.633 0.367 0.000
Q87 Other specified congenital malformation syndromes affecting multiple systems
0.632 0.368 0.000
F45.9 Somatoform disorder, unspecified
0.632 0.368 0.000
F14.1 Harmful use
0.631 0.369 0.000
M41.9 Scoliosis, unspecified
0.629 0.371 0.000
H15 Disorders of sclera
0.628 0.372 0.000
M13.94 Arthritis, unspecified (Hand)
0.628 0.372 0.000
H18.0 Corneal pigmentations and deposits
0.628 0.372 0.000
H70.8 Other mastoiditis and related conditions
0.628 0.372 0.000
H66.1 Chronic tubotympanic suppurative otitis media
0.626 0.374 0.000
I13 Hypertensive heart and renal disease
0.626 0.374 0.000
F50 Eating disorders
0.625 0.375 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.623 0.377 0.000
I08.8 Other multiple valve diseases
0.623 0.377 0.000
Q54.9 Hypospadias, unspecified
0.621 0.379 0.000
D84 Other immunodeficiencies
0.620 0.380 0.000
F40.9 Phobic anxiety disorder, unspecified
0.617 0.383 0.000
M11 Other crystal arthropathies
0.616 0.384 0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]
0.615 0.385 0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.613 0.387 0.000
Q01 Encephalocele
0.613 0.387 0.000
Q00 Anencephaly and similar malformations
0.613 0.387 0.000
Q02 Microcephaly
0.613 0.387 0.000
Q03 Congenital hydrocephalus
0.613 0.387 0.000
H74.9 Disorder of middle ear and mastoid, unspecified
0.612 0.388 0.000
F23 Acute and transient psychotic disorders
0.609 0.391 0.000
I36.9 Nonrheumatic tricuspid valve disorder, unspecified
0.609 0.391 0.000
I36.8 Other nonrheumatic tricuspid valve disorders
0.609 0.391 0.000
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency
0.609 0.391 0.000
I36.0 Nonrheumatic tricuspid (valve) stenosis
0.609 0.391 0.000
Q43.9 Congenital malformation of intestine, unspecified
0.608 0.392 0.000
I08.9 Multiple valve disease, unspecified
0.607 0.393 0.000
I11.0 Hypertensive heart disease with (congestive) heart failure
0.607 0.393 0.000
M41.99 Scoliosis, unspecified (Site unspecified)
0.607 0.393 0.000
M80.0 Postmenopausal osteoporosis with pathological fracture
0.605 0.395 0.000
I06.9 Rheumatic aortic valve disease, unspecified
0.605 0.395 0.000
F45.1 Undifferentiated somatoform disorder
0.604 0.395 0.000
Q56 Indeterminate sex and pseudohermaphroditism
0.604 0.396 0.000
F68 Other disorders of adult personality and behaviour
0.603 0.397 0.000
F66 Psychological and behavioural disorders associated with sexual development and orientation
0.603 0.397 0.000
F65 Disorders of sexual preference
0.603 0.397 0.000
F63 Habit and impulse disorders
0.603 0.397 0.000
H27.0 Aphakia
0.603 0.397 0.000
F48 Other neurotic disorders
0.602 0.398 0.000
Q31 Congenital malformations of larynx
0.601 0.399 0.000
H21.4 Pupillary membranes
0.601 0.399 0.000
H72.8 Other perforations of tympanic membrane
0.600 0.400 0.000
H72.0 Central perforation of tympanic membrane
0.600 0.400 0.000
M45.X2 Ankylosing spondylitis (Cervical region)
0.598 0.402 0.000
I15.1 Hypertension secondary to other renal disorders
0.596 0.404 0.000
F43.9 Reaction to severe stress, unspecified
0.595 0.405 0.000
Q04 Other congenital malformations of brain
0.595 0.405 0.000
H22.1 Iridocyclitis in other diseases classified elsewhere
0.593 0.407 0.000
F11.9 Unspecified mental and behavioural disorder
0.593 0.407 0.000
F11.8 Other mental and behavioural disorders
0.593 0.407 0.000
F11.7 Residual and late-onset psychotic disorder
0.593 0.407 0.000
F11.6 Amnesic syndrome
0.593 0.407 0.000
F11.5 Psychotic disorder
0.593 0.407 0.000
F11.4 Withdrawal state with delirium
0.593 0.407 0.000
F11.0 Acute intoxication
0.593 0.407 0.000
Q25.6 Stenosis of pulmonary artery
0.592 0.407 0.000
F19.2 Dependence syndrome
0.592 0.407 0.000
Q39.6 Diverticulum of oesophagus
0.590 0.409 0.000
Q28.2 Arteriovenous malformation of cerebral vessels
0.590 0.410 0.000
H18.3 Changes in corneal membranes
0.590 0.410 0.000
Q53 Undescended testicle
0.590 0.410 0.000
M80.8 Other osteoporosis with pathological fracture
0.589 0.411 0.000
D84.9 Immunodeficiency, unspecified
0.588 0.412 0.000
D80.9 Immunodeficiency with predominantly antibody defects, unspecified
0.587 0.413 0.000
F22 Persistent delusional disorders
0.587 0.413 0.000
Q86 Congenital malformation syndromes due to known exogenous causes, not elsewhere classified
0.586 0.414 0.000
Q84 Other congenital malformations of integument
0.586 0.414 0.000
Q81 Epidermolysis bullosa
0.586 0.414 0.000
Q80 Congenital ichthyosis
0.586 0.414 0.000
H80-H83 Diseases of inner ear
0.586 0.414 0.000
H74.8 Other specified disorders of middle ear and mastoid
0.586 0.414 0.000
Q43.1 Hirschsprung's disease
0.583 0.417 0.000
F14.9 Unspecified mental and behavioural disorder
0.582 0.418 0.000
F14.8 Other mental and behavioural disorders
0.582 0.418 0.000
F14.7 Residual and late-onset psychotic disorder
0.582 0.418 0.000
F14.6 Amnesic syndrome
0.582 0.418 0.000
F14.5 Psychotic disorder
0.582 0.418 0.000
F14.4 Withdrawal state with delirium
0.582 0.418 0.000
F14.3 Withdrawal state
0.582 0.418 0.000
F14.0 Acute intoxication
0.582 0.418 0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments
0.582 0.418 0.000
F62 Enduring personality changes, not attributable to brain damage and disease
0.582 0.418 0.000
Q07 Other congenital malformations of nervous system
0.581 0.418 0.000
F20 Schizophrenia
0.581 0.419 0.000
M85.0 Fibrous dysplasia (monostotic)
0.580 0.420 0.000
M00 Pyogenic arthritis
0.580 0.420 0.000
M05 Seropositive rheumatoid arthritis
0.579 0.421 0.000
Q22.1 Congenital pulmonary valve stenosis
0.578 0.421 0.000
H95.8 Other postprocedural disorders of ear and mastoid process
0.578 0.422 0.000
M80.1 Postoophorectomy osteoporosis with pathological fracture
0.577 0.423 0.000
Q40.3 Congenital malformation of stomach, unspecified
0.576 0.424 0.000
M60 Myositis
0.576 0.424 0.000
M82.10 Osteoporosis in endocrine disorders (Multiple sites)
0.575 0.425 0.000
F59 Unspecified behavioural syndromes associated with physiological disturbances and physical factors
0.574 0.425 0.000
F54 Psychological and behavioural factors associated with disorders or diseases classified elsewhere
0.574 0.425 0.000
H70.2 Petrositis
0.574 0.426 0.000
H70.0 Acute mastoiditis
0.574 0.426 0.000
H92.1 Otorrhoea
0.574 0.426 0.000
M80.5 Idiopathic osteoporosis with pathological fracture
0.574 0.426 0.000
Q40.1 Congenital hiatus hernia
0.574 0.426 0.000
H91.8 Other specified hearing loss
0.573 0.426 0.000
F45.8 Other somatoform disorders
0.574 0.426 0.000
Q43.0 Meckel's diverticulum
0.572 0.428 0.000
F53 Mental and behavioural disorders associated with the puerperium, not elsewhere classified
0.571 0.429 0.000
Q52.1 Doubling of vagina
0.571 0.429 0.000
F64 Gender identity disorders
0.571 0.429 0.000
H73.9 Disorder of tympanic membrane, unspecified
0.571 0.429 0.000
H90.8 Mixed conductive and sensorineural hearing loss, unspecified
0.570 0.430 0.000
F30-F39 Mood [affective] disorders
0.570 0.430 0.000
F28 Other nonorganic psychotic disorders
0.569 0.430 0.000
F24 Induced delusional disorder
0.569 0.430 0.000
F21 Schizotypal disorder
0.569 0.430 0.000
Q43.7 Persistent cloaca
0.568 0.431 0.000
Q43.6 Congenital fistula of rectum and anus
0.568 0.431 0.000
Q43.5 Ectopic anus
0.568 0.431 0.000
Q43.4 Duplication of intestine
0.568 0.431 0.000
Q43.2 Other congenital functional disorders of colon
0.568 0.431 0.000
Q39.9 Congenital malformation of oesophagus, unspecified
0.568 0.431 0.000
Q39.8 Other congenital malformations of oesophagus
0.568 0.431 0.000
Q39.5 Congenital dilatation of oesophagus
0.568 0.431 0.000
Q39.3 Congenital stenosis and stricture of oesophagus
0.568 0.431 0.000
Q39.2 Congenital tracheooesophageal fistula without atresia
0.568 0.431 0.000
Q39.1 Atresia of oesophagus with tracheooesophageal fistula
0.568 0.431 0.000
Q39.0 Atresia of oesophagus without fistula
0.568 0.431 0.000
F51 Nonorganic sleep disorders
0.566 0.433 0.000
Q40.9 Congenital malformation of upper alimentary tract, unspecified
0.565 0.435 0.000
Q40.8 Other specified congenital malformations of upper alimentary tract
0.565 0.435 0.000
Q40.0 Congenital hypertrophic pyloric stenosis
0.565 0.435 0.000
H95.0 Recurrent cholesteatoma of postmastoidectomy cavity
0.565 0.435 0.000
H91.1 Presbycusis
0.565 0.435 0.000
H18.7 Other corneal deformities
0.565 0.435 0.000
Q83.8 Other congenital malformations of breast
0.565 0.435 0.000
Q54.1 Hypospadias, penile
0.563 0.437 0.000
H66.3 Other chronic suppurative otitis media
0.563 0.437 0.000
H27.8 Other specified disorders of lens
0.562 0.438 0.000
H21.3 Cyst of iris, ciliary body and anterior chamber
0.562 0.438 0.000
I09.8 Other specified rheumatic heart diseases
0.561 0.439 0.000
I09.2 Chronic rheumatic pericarditis
0.561 0.439 0.000
I09.1 Rheumatic diseases of endocardium, valve unspecified
0.561 0.439 0.000
I09.0 Rheumatic myocarditis
0.561 0.439 0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere
0.560 0.440 0.000
Q43.3 Congenital malformations of intestinal fixation
0.560 0.440 0.000
M49 Spondylopathies in diseases classified elsewhere
0.560 0.440 0.000
M83 Adult osteomalacia
0.560 0.440 0.000
H53-H54 Visual disturbances and blindness
0.560 0.440 0.000
H55-H59 Other disorders of eye and adnexa
0.558 0.442 0.000
H72.2 Other marginal perforations of tympanic membrane
0.557 0.443 0.000
F25.1 Schizoaffective disorder, depressive type
0.557 0.443 0.000
I28 Other diseases of pulmonary vessels
0.556 0.444 0.000
F50.0 Anorexia nervosa
0.554 0.446 0.000
Q22.5 Ebstein's anomaly
0.552 0.447 0.000
M46 Other inflammatory spondylopathies
0.551 0.449 0.000
H66.4 Suppurative otitis media, unspecified
0.551 0.449 0.000
Q27.8 Other specified congenital malformations of peripheral vascular system
0.549 0.450 0.000
H70.1 Chronic mastoiditis
0.549 0.451 0.000
Q34 Other congenital malformations of respiratory system
0.549 0.451 0.000
Q33 Congenital malformations of lung
0.549 0.451 0.000
Q32 Congenital malformations of trachea and bronchus
0.549 0.451 0.000
Q30 Congenital malformations of nose
0.549 0.451 0.000
M82.11 Osteoporosis in endocrine disorders (Shoulder region)
0.549 0.451 0.000
F15.1 Harmful use
0.548 0.452 0.000
F45.4 Persistent somatoform pain disorder
0.546 0.454 0.000
Q05.8 Sacral spina bifida without hydrocephalus
0.546 0.454 0.000
Q05.7 Lumbar spina bifida without hydrocephalus
0.546 0.454 0.000
Q05.6 Thoracic spina bifida without hydrocephalus
0.546 0.454 0.000
Q05.5 Cervical spina bifida without hydrocephalus
0.546 0.454 0.000
Q05.3 Sacral spina bifida with hydrocephalus
0.546 0.454 0.000
Q05.2 Lumbar spina bifida with hydrocephalus
0.546 0.454 0.000
Q05.1 Thoracic spina bifida with hydrocephalus
0.546 0.454 0.000
Q05.0 Cervical spina bifida with hydrocephalus
0.546 0.454 0.000
I06.8 Other rheumatic aortic valve diseases
0.546 0.454 0.000
I06.2 Rheumatic aortic stenosis with insufficiency
0.546 0.454 0.000
I06.1 Rheumatic aortic insufficiency
0.546 0.454 0.000
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses
0.545 0.455 0.000
H66.2 Chronic atticoantral suppurative otitis media
0.545 0.455 0.000
Q55 Other congenital malformations of male genital organs
0.544 0.456 0.000
F19.9 Unspecified mental and behavioural disorder
0.543 0.456 0.000
F19.8 Other mental and behavioural disorders
0.543 0.456 0.000
F19.7 Residual and late-onset psychotic disorder
0.543 0.456 0.000
F19.6 Amnesic syndrome
0.543 0.456 0.000
F19.5 Psychotic disorder
0.543 0.456 0.000
F19.4 Withdrawal state with delirium
0.543 0.456 0.000
F19.3 Withdrawal state
0.543 0.456 0.000
F19.0 Acute intoxication
0.543 0.456 0.000
Q22.9 Congenital malformation of tricuspid valve, unspecified
0.542 0.457 0.000
Q22.8 Other congenital malformations of tricuspid valve
0.542 0.457 0.000
Q22.6 Hypoplastic right heart syndrome
0.542 0.457 0.000
Q22.4 Congenital tricuspid stenosis
0.542 0.457 0.000
Q22.3 Other congenital malformations of pulmonary valve
0.542 0.457 0.000
Q22.2 Congenital pulmonary valve insufficiency
0.542 0.457 0.000
Q22.0 Pulmonary valve atresia
0.542 0.457 0.000
H90.7 Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
0.542 0.458 0.000
M85.6 Other cyst of bone
0.541 0.459 0.000
M08 Juvenile arthritis
0.541 0.459 0.000
M13.96 Arthritis, unspecified (Lower leg)
0.541 0.459 0.000
F45.2 Hypochondriacal disorder
0.540 0.459 0.000
Q28.9 Congenital malformation of circulatory system, unspecified
0.540 0.460 0.000
Q28.8 Other specified congenital malformations of circulatory system
0.540 0.460 0.000
Q28.3 Other malformations of cerebral vessels
0.540 0.460 0.000
Q28.1 Other malformations of precerebral vessels
0.540 0.460 0.000
H73.1 Chronic myringitis
0.539 0.460 0.000
F44.5 Dissociative convulsions
0.538 0.461 0.000
I06.0 Rheumatic aortic stenosis
0.537 0.463 0.000
D80.1 Nonfamilial hypogammaglobulinaemia
0.536 0.464 0.000
Q52.9 Congenital malformation of female genitalia, unspecified
0.536 0.464 0.000
Q52.8 Other specified congenital malformations of female genitalia
0.536 0.464 0.000
Q52.7 Other congenital malformations of vulva
0.536 0.464 0.000
Q52.6 Congenital malformation of clitoris
0.536 0.464 0.000
Q52.4 Other congenital malformations of vagina
0.536 0.464 0.000
Q52.3 Imperforate hymen
0.536 0.464 0.000
Q52.2 Congenital rectovaginal fistula
0.536 0.464 0.000
Q52.0 Congenital absence of vagina
0.536 0.464 0.000
I40.0 Infective myocarditis
0.535 0.465 0.000
M13.91 Arthritis, unspecified (Shoulder region)
0.535 0.465 0.000
F79 Unspecified mental retardation
0.534 0.466 0.000
F19.1 Harmful use
0.534 0.466 0.000
F90 Hyperkinetic disorders
0.533 0.467 0.000
Q24 Other congenital malformations of heart
0.532 0.468 0.000
H16.2 Keratoconjunctivitis
0.532 0.468 0.000
H80 Otosclerosis
0.531 0.469 0.000
M13.98 Arthritis, unspecified (Other)
0.530 0.470 0.000
M81 Osteoporosis without pathological fracture
0.530 0.470 0.000
F60 Specific personality disorders
0.529 0.470 0.000
Q28.0 Arteriovenous malformation of precerebral vessels
0.529 0.471 0.000
M80.00 Postmenopausal osteoporosis with pathological fracture (Multiple sites)
0.529 0.471 0.000
M02 Reactive arthropathies
0.529 0.471 0.000
Q21 Congenital malformations of cardiac septa
0.528 0.472 0.000
F15.9 Unspecified mental and behavioural disorder
0.528 0.472 0.000
F15.8 Other mental and behavioural disorders
0.528 0.472 0.000
F15.7 Residual and late-onset psychotic disorder
0.528 0.472 0.000
F15.6 Amnesic syndrome
0.528 0.472 0.000
F15.5 Psychotic disorder
0.528 0.472 0.000
F15.4 Withdrawal state with delirium
0.528 0.472 0.000
F15.3 Withdrawal state
0.528 0.472 0.000
F15.2 Dependence syndrome
0.528 0.472 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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