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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs1064694
log Bayes Factor = 211.171
Chromosome 6   position 32,546,838  (GRCh37) Explore rs1064694 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
E10.1 With ketoacidosis
0.000 0.000 1.000
H36.0 Diabetic retinopathy
0.000 0.000 1.000
J45.9 Asthma, unspecified
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
E14 Unspecified diabetes mellitus
0.000 0.000 1.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
G35 Multiple sclerosis
1.000 0.000 0.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
J40-J47 Chronic lower respiratory diseases
0.000 0.000 1.000
Chapter XI Diseases of the digestive system
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
M06 Other rheumatoid arthritis
0.000 0.000 1.000
M05-M14 Inflammatory polyarthropathies
0.000 0.000 1.000
E16.2 Hypoglycaemia, unspecified
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
# Top node
0.000 0.000 1.000
E11.9 Without complications
0.000 0.000 1.000
E16 Other disorders of pancreatic internal secretion
0.000 0.000 1.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.000 1.000
J45 Asthma
0.000 0.000 1.000
K51.9 Ulcerative colitis, unspecified
1.000 0.000 0.000
J44 Other chronic obstructive pulmonary disease
0.000 0.000 1.000
M05 Seropositive rheumatoid arthritis
0.000 0.000 1.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.000 1.000
E14.9 Without complications
0.000 0.000 1.000
K51 Ulcerative colitis
1.000 0.000 0.000
E10.4 With neurological complications
0.000 0.000 1.000
Chapter X Diseases of the respiratory system
0.000 0.001 0.999
H36 Retinal disorders in diseases classified elsewhere
0.000 0.001 0.999
K90 Intestinal malabsorption
0.000 0.001 0.999
K90-K93 Other diseases of the digestive system
0.000 0.001 0.999
Chapter VII Diseases of the eye and adnexa
0.000 0.001 0.999
H30-H36 Disorders of choroid and retina
0.000 0.001 0.999
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.002 0.998
E83.1 Disorders of iron metabolism
0.998 0.002 0.000
E14.3 With ophthalmic complications
0.000 0.003 0.997
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.003 0.997
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.000 0.004 0.996
E78.0 Pure hypercholesterolaemia
0.000 0.004 0.996
K55-K64 Other diseases of intestines
0.000 0.005 0.995
G35-G37 Demyelinating diseases of the central nervous system
0.994 0.005 0.000
K51.3 Ulcerative (chronic) rectosigmoiditis
0.994 0.006 0.000
K82 Other diseases of gallbladder
0.000 0.007 0.993
G37 Other demyelinating diseases of central nervous system
0.993 0.007 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.000 0.007 0.993
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.000 0.008 0.992
J33.9 Nasal polyp, unspecified
0.000 0.008 0.992
K70-K77 Diseases of liver
0.000 0.008 0.992
G37.9 Demyelinating disease of central nervous system, unspecified
0.991 0.009 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.009 0.991
J33 Nasal polyp
0.000 0.009 0.991
K82.8 Other specified diseases of gallbladder
0.000 0.010 0.990
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.010 0.990
E70-E90 Metabolic disorders
0.000 0.013 0.987
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.000 0.013 0.987
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.014 0.986
H43-H45 Disorders of vitreous body and globe
0.000 0.014 0.986
E05.9 Thyrotoxicosis, unspecified
0.000 0.014 0.986
K50-K52 Noninfective enteritis and colitis
0.005 0.018 0.977
H43 Disorders of vitreous body
0.000 0.019 0.981
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.021 0.979
K63 Other diseases of intestine
0.000 0.022 0.978
E10.5 With peripheral circulatory complications
0.000 0.023 0.977
E11.3 With ophthalmic complications
0.000 0.025 0.975
K51.8 Other ulcerative colitis
0.969 0.031 0.000
K63.9 Disease of intestine, unspecified
0.000 0.034 0.966
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.034 0.966
J30-J39 Other diseases of upper respiratory tract
0.000 0.036 0.964
K74 Fibrosis and cirrhosis of liver
0.000 0.037 0.963
E11.1 With ketoacidosis
0.000 0.039 0.961
K60 Fissure and fistula of anal and rectal regions
0.000 0.039 0.961
H40-H42 Glaucoma
0.000 0.044 0.956
J33.8 Other polyp of sinus
0.000 0.046 0.954
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.054 0.946
K58 Irritable bowel syndrome
0.000 0.056 0.944
H43.3 Other vitreous opacities
0.000 0.057 0.943
K75 Other inflammatory liver diseases
0.000 0.057 0.943
E10.2 With renal complications
0.000 0.062 0.938
K50 Crohn's disease [regional enteritis]
0.000 0.062 0.938
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.000 0.065 0.935
H43.8 Other disorders of vitreous body
0.000 0.067 0.933
K63.3 Ulcer of intestine
0.000 0.070 0.930
K58.0 Irritable bowel syndrome with diarrhoea
0.000 0.070 0.930
K72 Hepatic failure, not elsewhere classified
0.000 0.071 0.929
J46 Status asthmaticus
0.000 0.072 0.928
J43 Emphysema
0.000 0.074 0.926
H40 Glaucoma
0.000 0.075 0.925
K74.3 Primary biliary cirrhosis
0.000 0.075 0.925
E06 Thyroiditis
0.000 0.076 0.924
L43.9 Lichen planus, unspecified
0.000 0.078 0.922
L43 Lichen planus
0.000 0.078 0.922
L40-L45 Papulosquamous disorders
0.000 0.078 0.922
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.081 0.919
E07 Other disorders of thyroid
0.000 0.081 0.919
H40.9 Glaucoma, unspecified
0.000 0.082 0.918
H34 Retinal vascular occlusions
0.000 0.082 0.918
M06.0 Seronegative rheumatoid arthritis
0.000 0.084 0.916
K75.4 Autoimmune hepatitis
0.000 0.085 0.915
K62 Other diseases of anus and rectum
0.000 0.086 0.914
K86 Other diseases of pancreas
0.000 0.087 0.913
K82.1 Hydrops of gallbladder
0.000 0.091 0.909
J33.0 Polyp of nasal cavity
0.000 0.092 0.908
L40 Psoriasis
0.000 0.092 0.908
K81 Cholecystitis
0.000 0.094 0.906
E11.5 With peripheral circulatory complications
0.000 0.098 0.902
E03.8 Other specified hypothyroidism
0.000 0.098 0.902
K60.0 Acute anal fissure
0.000 0.100 0.900
J44.9 Chronic obstructive pulmonary disease, unspecified
0.000 0.101 0.899
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.101 0.899
L40.5 Arthropathic psoriasis
0.000 0.102 0.898
J86 Pyothorax
0.000 0.102 0.898
M65-M68 Disorders of synovium and tendon
0.000 0.107 0.893
E11.2 With renal complications
0.000 0.111 0.889
M07 Psoriatic and enteropathic arthropathies
0.000 0.112 0.888
K52 Other non-infective gastro-enteritis and colitis
0.001 0.113 0.887
K62.1 Rectal polyp
0.000 0.117 0.883
E11.6 With other specified complications
0.000 0.117 0.883
K62.4 Stenosis of anus and rectum
0.000 0.125 0.875
K60.2 Anal fissure, unspecified
0.000 0.126 0.874
E06.3 Autoimmune thyroiditis
0.000 0.127 0.873
E07.9 Disorder of thyroid, unspecified
0.000 0.128 0.872
K51.2 Ulcerative (chronic) proctitis
0.870 0.130 0.000
E13 Other specified diabetes mellitus
0.000 0.130 0.870
K81.1 Chronic cholecystitis
0.000 0.132 0.868
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.138 0.862
J43.9 Emphysema, unspecified
0.000 0.138 0.862
M70-M79 Other soft tissue disorders
0.000 0.139 0.861
H25-H28 Disorders of lens
0.000 0.141 0.859
K50.1 Crohn's disease of large intestine
0.000 0.142 0.858
I20-I25 Ischaemic heart diseases
0.000 0.147 0.853
Chapter IX Diseases of the circulatory system
0.000 0.147 0.853
E78.5 Hyperlipidaemia, unspecified
0.000 0.148 0.852
K55 Vascular disorders of intestine
0.000 0.149 0.851
K86.2 Cyst of pancreas
0.000 0.156 0.844
K60.5 Anorectal fistula
0.000 0.158 0.841
I20 Angina pectoris
0.000 0.159 0.841
M06.3 Rheumatoid nodule
0.000 0.159 0.841
K50.8 Other Crohn's disease
0.000 0.160 0.840
K72.9 Hepatic failure, unspecified
0.000 0.161 0.839
I10-I15 Hypertensive diseases
0.000 0.164 0.836
K63.4 Enteroptosis
0.000 0.165 0.835
J86.9 Pyothorax without fistula
0.000 0.168 0.832
K74.5 Biliary cirrhosis, unspecified
0.000 0.172 0.828
M65 Synovitis and tenosynovitis
0.000 0.174 0.826
M06.4 Inflammatory polyarthropathy
0.000 0.174 0.826
K52.1 Toxic gastro-enteritis and colitis
0.000 0.178 0.822
E78.2 Mixed hyperlipidaemia
0.000 0.179 0.821
M77 Other enthesopathies
0.000 0.179 0.821
I22 Subsequent myocardial infarction
0.000 0.180 0.820
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.181 0.819
K62.0 Anal polyp
0.000 0.183 0.817
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.184 0.816
G37.8 Other specified demyelinating diseases of central nervous system
0.815 0.185 0.000
M77.1 Lateral epicondylitis
0.000 0.185 0.815
K73 Chronic hepatitis, not elsewhere classified
0.000 0.187 0.813
H27 Other disorders of lens
0.000 0.187 0.813
K51.4 Pseudopolyposis of colon
0.811 0.189 0.000
M77.12 Lateral epicondylitis (Upper arm)
0.000 0.189 0.811
M07.3 Other psoriatic arthropathies
0.000 0.193 0.807
H40.1 Primary open-angle glaucoma
0.000 0.193 0.807
H34.8 Other retinal vascular occlusions
0.000 0.199 0.801
E16.1 Other hypoglycaemia
0.000 0.201 0.799
K72.0 Acute and subacute hepatic failure
0.000 0.201 0.799
E40-E46 Malnutrition
0.000 0.203 0.797
K51.5 Mucosal proctocolitis
0.796 0.204 0.000
J86.0 Pyothorax with fistula
0.000 0.206 0.794
E78.1 Pure hyperglyceridaemia
0.000 0.207 0.793
M14 Arthropathies in other diseases classified elsewhere
0.000 0.207 0.793
J37 Chronic laryngitis and laryngotracheitis
0.000 0.209 0.791
I20.9 Angina pectoris, unspecified
0.000 0.209 0.791
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.211 0.789
I20.0 Unstable angina
0.000 0.213 0.787
I20.1 Angina pectoris with documented spasm
0.000 0.215 0.785
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.216 0.783
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.783 0.216 0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.217 0.783
K81.9 Cholecystitis, unspecified
0.000 0.217 0.783
K86.1 Other chronic pancreatitis
0.000 0.220 0.780
E13.9 Without complications
0.000 0.224 0.776
K82.9 Disease of gallbladder, unspecified
0.000 0.224 0.776
M65.4 Radial styloid tenosynovitis [de Quervain]
0.000 0.225 0.775
J95-J99 Other diseases of the respiratory system
0.000 0.225 0.775
M11 Other crystal arthropathies
0.000 0.228 0.772
K90.9 Intestinal malabsorption, unspecified
0.000 0.228 0.772
K75.9 Inflammatory liver disease, unspecified
0.000 0.232 0.768
I10 Essential (primary) hypertension
0.000 0.233 0.767
H40.5 Glaucoma secondary to other eye disorders
0.000 0.236 0.764
H43.1 Vitreous haemorrhage
0.000 0.236 0.764
K55.2 Angiodysplasia of colon
0.000 0.236 0.764
E83 Disorders of mineral metabolism
0.691 0.240 0.069
K50.0 Crohn's disease of small intestine
0.000 0.240 0.760
E88 Other metabolic disorders
0.000 0.240 0.759
K63.2 Fistula of intestine
0.000 0.244 0.756
I12 Hypertensive renal disease
0.000 0.244 0.756
K52.8 Other specified non-infective gastro-enteritis and colitis
0.000 0.245 0.755
K62.7 Radiation proctitis
0.000 0.248 0.752
H43.9 Disorder of vitreous body, unspecified
0.000 0.250 0.749
K82.3 Fistula of gallbladder
0.000 0.256 0.744
E11.0 With coma
0.000 0.256 0.743
M75 Shoulder lesions
0.000 0.257 0.743
K86.3 Pseudocyst of pancreas
0.000 0.259 0.741
H34.2 Other retinal artery occlusions
0.000 0.260 0.740
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.263 0.737
H34.1 Central retinal artery occlusion
0.000 0.263 0.736
H27.0 Aphakia
0.000 0.265 0.735
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.266 0.734
K74.6 Other and unspecified cirrhosis of liver
0.000 0.266 0.734
L40.9 Psoriasis, unspecified
0.000 0.266 0.734
L43.8 Other lichen planus
0.000 0.267 0.733
K55.8 Other vascular disorders of intestine
0.000 0.268 0.732
E74 Other disorders of carbohydrate metabolism
0.000 0.269 0.731
H43.2 Crystalline deposits in vitreous body
0.000 0.271 0.729
M65.9 Synovitis and tenosynovitis, unspecified
0.000 0.273 0.727
H30 Chorioretinal inflammation
0.000 0.276 0.724
M75.0 Adhesive capsulitis of shoulder
0.000 0.277 0.723
K52.9 Non-infective gastro-enteritis and colitis, unspecified
0.000 0.278 0.722
K82.2 Perforation of gallbladder
0.000 0.281 0.719
K51.0 Ulcerative (chronic) enterocolitis
0.719 0.281 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.283 0.717
E10.8 With unspecified complications
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.283 0.717
E10.6 With other specified complications
0.000 0.283 0.717
E10.0 With coma
0.000 0.283 0.717
E11.7 With multiple complications
0.000 0.283 0.717
E14.8 With unspecified complications
0.000 0.283 0.717
E14.7 With multiple complications
0.000 0.283 0.717
E14.6 With other specified complications
0.000 0.283 0.717
E14.5 With peripheral circulatory complications
0.000 0.283 0.717
E14.4 With neurological complications
0.000 0.283 0.717
E14.2 Withrenal complications
0.000 0.283 0.717
E14.1 With ketoacidosis
0.000 0.283 0.717
E14.0 With coma
0.000 0.283 0.717
M06.8 Other specified rheumatoid arthritis
0.000 0.283 0.717
M06.2 Rheumatoid bursitis
0.000 0.283 0.717
M06.1 Adult-onset Still's disease
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.283 0.717
M08 Juvenile arthritis
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.717
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.283 0.717
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.283 0.717
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.283 0.717
E16.4 Abnormal secretion of gastrin
0.000 0.283 0.717
E16.3 Increased secretion of glucagon
0.000 0.283 0.717
E15 Nondiabetic hypoglycaemic coma
0.000 0.283 0.717
J45.8 Mixed asthma
0.000 0.283 0.717
J45.1 Nonallergic asthma
0.000 0.283 0.717
M05.8 Other seropositive rheumatoid arthritis
0.000 0.283 0.717
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.283 0.717
M05.2 Rheumatoid vasculitis
0.000 0.283 0.717
M05.1 Rheumatoid lung disease
0.000 0.283 0.717
M05.0 Felty's syndrome
0.000 0.283 0.717
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.283 0.717
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.283 0.717
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.283 0.717
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.283 0.717
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.283 0.717
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.283 0.717
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.283 0.717
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.283 0.717
K51.1 Ulcerative (chronic) ileocolitis
0.717 0.283 0.000
I15 Secondary hypertension
0.000 0.284 0.716
H36.8 Other retinal disorders in diseases classified elsewhere
0.000 0.284 0.716
K90.3 Pancreatic steatorrhoea
0.000 0.284 0.716
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.284 0.716
K90.1 Tropical sprue
0.000 0.284 0.716
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.284 0.716
H32 Chorioretinal disorders in diseases classified elsewhere
0.000 0.284 0.716
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.000 0.286 0.714
K64 Haemorrhoids and perianal venous thrombosis
0.000 0.286 0.714
G36 Other acute disseminated demyelination
0.713 0.287 0.000
G37.5 Concentric sclerosis [Balo]
0.712 0.288 0.000
G37.4 Subacute necrotising myelitis
0.712 0.288 0.000
G37.2 Central pontine myelinolysis
0.712 0.288 0.000
G37.1 Central demyelination of corpus callosum
0.712 0.288 0.000
G37.0 Diffuse sclerosis
0.712 0.288 0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.000 0.289 0.711
K77 Liver disorders in diseases classified elsewhere
0.000 0.289 0.711
K71 Toxic liver disease
0.000 0.289 0.711
E78.6 Lipoprotein deficiency
0.000 0.289 0.711
E78.3 Hyperchylomicronaemia
0.000 0.289 0.711
J33.1 Polypoid sinus degeneration
0.000 0.290 0.710
J43.2 Centrilobular emphysema
0.000 0.290 0.710
E05.5 Thyroid crisis or storm
0.000 0.290 0.709
E05.4 Thyrotoxicosis factitia
0.000 0.290 0.709
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.290 0.709
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.290 0.709
M65.44 Radial styloid tenosynovitis [de Quervain] (Hand)
0.000 0.291 0.709
E77 Disorders of glycoprotein metabolism
0.000 0.292 0.708
E76 Disorders of glycosaminoglycan metabolism
0.000 0.292 0.708
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.292 0.708
E72 Other disorders of amino-acid metabolism
0.000 0.292 0.708
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.292 0.708
E70 Disorders of aromatic amino-acid metabolism
0.000 0.292 0.708
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.292 0.708
H45 Disorders of vitreous body and globe in diseases classified elsewhere
0.000 0.293 0.707
E11.8 With unspecified complications
0.000 0.295 0.705
H43.0 Vitreous prolapse
0.000 0.297 0.703
J41 Simple and mucopurulent chronic bronchitis
0.000 0.298 0.702
E11.4 With neurological complications
0.000 0.299 0.701
I24 Other acute ischaemic heart diseases
0.000 0.300 0.700
H25 Senile cataract
0.000 0.304 0.696
M14.6 Neuropathic arthropathy
0.000 0.306 0.694
K74.4 Secondary biliary cirrhosis
0.000 0.309 0.690
K74.2 Hepatic fibrosis with hepatic sclerosis
0.000 0.309 0.690
K74.1 Hepatic sclerosis
0.000 0.309 0.690
K60.1 Chronic anal fissure
0.000 0.310 0.690
E05.8 Other thyrotoxicosis
0.000 0.311 0.689
H25.1 Senile nuclear cataract
0.000 0.312 0.688
M06.34 Rheumatoid nodule (Hand)
0.000 0.312 0.687
M75.2 Bicipital tendinitis
0.000 0.314 0.686
H42 Glaucoma in diseases classified elsewhere
0.000 0.315 0.685
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.316 0.684
H27.8 Other specified disorders of lens
0.000 0.316 0.684
M66 Spontaneous rupture of synovium and tendon
0.000 0.317 0.683
K75.3 Granulomatous hepatitis, not elsewhere classified
0.000 0.324 0.676
K75.2 Nonspecific reactive hepatitis
0.000 0.324 0.676
K75.1 Phlebitis of portal vein
0.000 0.324 0.676
J32 Chronic sinusitis
0.000 0.325 0.675
J42 Unspecified chronic bronchitis
0.000 0.327 0.673
K86.0 Alcohol-induced chronic pancreatitis
0.000 0.327 0.673
K62.2 Anal prolapse
0.000 0.327 0.673
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.328 0.672
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.328 0.672
I12.9 Hypertensive renal disease without renal failure
0.000 0.332 0.668
J37.0 Chronic laryngitis
0.000 0.332 0.668
M12 Other specific arthropathies
0.000 0.333 0.667
K72.1 Chronic hepatic failure
0.000 0.334 0.666
E84 Cystic fibrosis
0.000 0.336 0.664
J43.8 Other emphysema
0.000 0.336 0.664
J43.1 Panlobular emphysema
0.000 0.336 0.664
J43.0 MacLeod's syndrome
0.000 0.336 0.664
H40.6 Glaucoma secondary to drugs
0.000 0.337 0.663
H40.4 Glaucoma secondary to eye inflammation
0.000 0.337 0.663
H40.3 Glaucoma secondary to eye trauma
0.000 0.337 0.663
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.337 0.663
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.337 0.663
E06.5 Other chronic thyroiditis
0.000 0.337 0.662
E06.4 Drug-induced thyroiditis
0.000 0.337 0.662
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.337 0.662
E06.1 Subacute thyroiditis
0.000 0.337 0.662
E06.0 Acute thyroiditis
0.000 0.337 0.662
L43.3 Subacute (active) lichen planus
0.000 0.339 0.661
L43.2 Lichenoid drug reaction
0.000 0.339 0.661
L43.1 Bullous lichen planus
0.000 0.339 0.661
L43.0 Hypertrophic lichen planus
0.000 0.339 0.661
L44 Other papulosquamous disorders
0.000 0.339 0.661
L41 Parapsoriasis
0.000 0.339 0.661
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.339 0.661
E07.1 Dyshormogenetic goitre
0.000 0.341 0.659
E07.0 Hypersecretion of calcitonin
0.000 0.341 0.659
H34.0 Transient retinal artery occlusion
0.000 0.341 0.658
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.343 0.657
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.343 0.657
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.343 0.657
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.343 0.657
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.343 0.657
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.343 0.657
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.343 0.657
K82.0 Obstruction of gallbladder
0.000 0.343 0.657
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.344 0.656
J98 Other respiratory disorders
0.000 0.346 0.654
H34.9 Retinal vascular occlusion, unspecified
0.000 0.347 0.653
L40.4 Guttate psoriasis
0.000 0.349 0.651
L40.3 Pustulosis palmaris et plantaris
0.000 0.349 0.651
L40.2 Acrodermatitis continua
0.000 0.349 0.651
L40.1 Generalised pustular psoriasis
0.000 0.349 0.651
M65.43 Radial styloid tenosynovitis [de Quervain] (Forearm)
0.000 0.349 0.651
E46 Unspecified protein-energy malnutrition
0.000 0.349 0.651
L40.8 Other psoriasis
0.000 0.350 0.649
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.351 0.649
K90.8 Other intestinal malabsorption
0.000 0.353 0.647
E06.9 Thyroiditis, unspecified
0.000 0.356 0.644
K73.9 Chronic hepatitis, unspecified
0.000 0.356 0.644
E79 Disorders of purine and pyrimidine metabolism
0.000 0.358 0.642
E78.8 Other disorders of lipoprotein metabolism
0.000 0.359 0.641
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.000 0.360 0.640
K86.8 Other specified diseases of pancreas
0.000 0.360 0.640
K73.2 Chronic active hepatitis, not elsewhere classified
0.000 0.361 0.639
H27.1 Dislocation of lens
0.000 0.362 0.638
M07.6 Other enteropathic arthropathies
0.000 0.363 0.636
M07.5 Arthropathy in ulcerative colitis
0.000 0.363 0.636
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.000 0.363 0.636
M07.2 Psoriatic spondylitis
0.000 0.363 0.636
M07.1 Arthritis mutilans
0.000 0.363 0.636
M07.0 Distal interphalangeal psoriatic arthropathy
0.000 0.363 0.636
K55.1 Chronic vascular disorders of intestine
0.000 0.363 0.636
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.000 0.365 0.635
K52.2 Allergic and dietetic gastro-enteritis and colitis
0.001 0.366 0.633
I23 Certain current complications following acute myocardial infarction
0.000 0.369 0.631
M65.93 Synovitis and tenosynovitis, unspecified (Forearm)
0.000 0.372 0.628
J98.4 Other disorders of lung
0.000 0.375 0.625
E13.8 With unspecified complications
0.000 0.376 0.624
E13.7 With multiple complications
0.000 0.376 0.624
E13.6 With other specified complications
0.000 0.376 0.624
E13.5 With peripheral circulatory complications
0.000 0.376 0.624
E13.4 With neurological complications
0.000 0.376 0.624
E13.3 With ophthalmic complications
0.000 0.376 0.624
E13.2 With renal complications
0.000 0.376 0.624
E13.1 With ketoacidosis
0.000 0.376 0.624
E13.0 With coma
0.000 0.376 0.624
M65.1 Other infective (teno)synovitis
0.000 0.378 0.622
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.378 0.622
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.379 0.621
E03.1 Congenital hypothyroidism without goitre
0.000 0.381 0.619
I25 Chronic ischaemic heart disease
0.000 0.381 0.619
M10 Gout
0.000 0.382 0.618
E83.3 Disorders of phosphorus metabolism
0.595 0.382 0.023
M73 Soft tissue disorders in diseases classified elsewhere
0.000 0.383 0.617
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.383 0.617
H28 Cataract and other disorders of lens in diseases classified elsewhere
0.000 0.384 0.616
I12.0 Hypertensive renal disease with renal failure
0.000 0.385 0.615
K81.8 Other cholecystitis
0.000 0.386 0.614
K75.8 Other specified inflammatory liver diseases
0.000 0.388 0.612
K74.0 Hepatic fibrosis
0.000 0.388 0.612
I00-I02 Acute rheumatic fever
0.000 0.388 0.612
J85 Abscess of lung and mediastinum
0.000 0.390 0.610
M72 Fibroblastic disorders
0.000 0.391 0.609
M11.2 Other chondrocalcinosis
0.000 0.391 0.609
I15.1 Hypertension secondary to other renal disorders
0.000 0.392 0.608
E83.9 Disorder of mineral metabolism, unspecified
0.566 0.394 0.041
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.000 0.394 0.606
L10-L14 Bullous disorders
0.000 0.396 0.604
M70 Soft tissue disorders related to use, overuse and pressure
0.000 0.397 0.603
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.397 0.603
M06.38 Rheumatoid nodule (Other)
0.000 0.397 0.603
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.397 0.603
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.397 0.603
M06.33 Rheumatoid nodule (Forearm)
0.000 0.397 0.603
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.397 0.603
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.397 0.603
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.397 0.603
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.000 0.398 0.602
E07.8 Other specified disorders of thyroid
0.000 0.399 0.600
I13 Hypertensive heart and renal disease
0.000 0.401 0.599
E73 Lactose intolerance
0.000 0.403 0.597
M71 Other bursopathies
0.000 0.404 0.596
L42 Pityriasis rosea
0.000 0.404 0.596
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified
0.000 0.407 0.593
M65.2 Calcific tendinitis
0.000 0.408 0.592
M65.0 Abscess of tendon sheath
0.000 0.408 0.592
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.408 0.592
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.408 0.592
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.408 0.592
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.408 0.592
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.408 0.592
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.408 0.592
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.408 0.592
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.408 0.592
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.408 0.592
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.410 0.590
M77.8 Other enthesopathies, not elsewhere classified
0.000 0.411 0.589
M77.3 Calcaneal spur
0.000 0.411 0.589
M77.2 Periarthritis of wrist
0.000 0.411 0.589
E85 Amyloidosis
0.000 0.413 0.586
M77.19 Lateral epicondylitis (Site unspecified)
0.000 0.416 0.584
M77.18 Lateral epicondylitis-Other
0.000 0.416 0.584
M77.17 Lateral epicondylitis-Ankle/Foot
0.000 0.416 0.584
M77.16 Lateral epicondylitis (Lower leg)
0.000 0.416 0.584
M77.15 Lateral epicondylitis (Pelvic region and thigh)
0.000 0.416 0.584
M77.14 Lateral epicondylitis-Hand
0.000 0.416 0.584
M77.13 Lateral epicondylitis-Forearm
0.000 0.416 0.584
M77.11 Lateral epicondylitis-Shldr region
0.000 0.416 0.584
M77.10 Lateral epicondylitis (Multiple sites)
0.000 0.416 0.584
M76 Enthesopathies of lower limb, excluding foot
0.000 0.416 0.584
I11 Hypertensive heart disease
0.000 0.416 0.584
K91.0 Vomiting following gastro-intestinal surgery
0.000 0.417 0.583
M67 Other disorders of synovium and tendon
0.000 0.417 0.583
K73.8 Other chronic hepatitis, not elsewhere classified
0.000 0.417 0.583
K73.1 Chronic lobular hepatitis, not elsewhere classified
0.000 0.417 0.583
K73.0 Chronic persistent hepatitis, not elsewhere classified
0.000 0.417 0.583
H27.9 Disorder of lens, unspecified
0.000 0.417 0.583
J95 Postprocedural respiratory disorders, not elsewhere classified
0.000 0.418 0.582
K60.4 Rectal fistula
0.000 0.420 0.580
M07.38 Other psoriatic arthropathies (Other)
0.000 0.421 0.579
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.000 0.421 0.579
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.421 0.579
M07.34 Other psoriatic arthropathies (Hand)
0.000 0.421 0.579
M07.33 Other psoriatic arthropathies (Forearm)
0.000 0.421 0.579
M07.32 Other psoriatic arthropathies (Upper arm)
0.000 0.421 0.579
M07.31 Other psoriatic arthropathies (Shoulder region)
0.000 0.421 0.579
E88.2 Lipomatosis, not elsewhere classified
0.000 0.422 0.578
J32.4 Chronic pansinusitis
0.000 0.427 0.573
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.429 0.571
E45 Retarded development following protein-energy malnutrition
0.000 0.429 0.571
E43 Unspecified severe protein-energy malnutrition
0.000 0.429 0.571
E42 Marasmic kwashiorkor
0.000 0.429 0.571

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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