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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs10838725
log Bayes Factor = 2.31198
Chromosome 11   position 47,557,871  (GRCh37) Explore rs10838725 on Ensembl!
Variant rs10838725 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
H30-H36 Disorders of choroid and retina
0.000 0.050 0.950
H36 Retinal disorders in diseases classified elsewhere
0.000 0.055 0.945
H36.0 Diabetic retinopathy
0.000 0.059 0.941
H34 Retinal vascular occlusions
0.000 0.064 0.936
H34.8 Other retinal vascular occlusions
0.000 0.072 0.928
H33 Retinal detachments and breaks
0.000 0.083 0.917
H35 Other retinal disorders
0.000 0.086 0.914
H33.5 Other retinal detachments
0.000 0.135 0.865
H31 Other disorders of choroid
0.000 0.141 0.859
E11 Non-insulin-dependent diabetes mellitus
0.000 0.145 0.855
E11.9 Without complications
0.000 0.149 0.851
H33.0 Retinal detachment with retinal break
0.000 0.151 0.849
E11.3 With ophthalmic complications
0.000 0.158 0.842
H35.5 Hereditary retinal dystrophy
0.000 0.178 0.822
H35.2 Other proliferative retinopathy
0.000 0.196 0.804
H35.9 Retinal disorder, unspecified
0.000 0.221 0.779
H35.4 Peripheral retinal degeneration
0.000 0.223 0.777
E11.4 With neurological complications
0.000 0.226 0.774
E10-E14 Diabetes mellitus
0.000 0.238 0.762
H31.0 Chorioretinal scars
0.000 0.246 0.754
E11.2 With renal complications
0.000 0.250 0.750
E14 Unspecified diabetes mellitus
0.000 0.254 0.746
E14.3 With ophthalmic complications
0.000 0.261 0.739
H34.1 Central retinal artery occlusion
0.000 0.267 0.733
H33.1 Retinoschisis and retinal cysts
0.000 0.285 0.715
H33.3 Retinal breaks without detachment
0.000 0.291 0.709
H35.3 Degeneration of macula and posterior pole
0.000 0.292 0.708
H32 Chorioretinal disorders in diseases classified elsewhere
0.000 0.319 0.681
H36.8 Other retinal disorders in diseases classified elsewhere
0.000 0.323 0.677
E11.1 With ketoacidosis
0.000 0.328 0.672
H34.0 Transient retinal artery occlusion
0.000 0.329 0.671
H35.8 Other specified retinal disorders
0.000 0.334 0.666
H31.8 Other specified disorders of choroid
0.000 0.339 0.661
H35.1 Retinopathy of prematurity
0.000 0.345 0.655
H31.1 Choroidal degeneration
0.000 0.348 0.652
H34.9 Retinal vascular occlusion, unspecified
0.000 0.357 0.643
H31.3 Choroidal haemorrhage and rupture
0.000 0.359 0.641
H33.4 Traction detachment of retina
0.000 0.364 0.636
E11.8 With unspecified complications
0.000 0.372 0.628
H35.0 Background retinopathy and retinal vascular changes
0.000 0.375 0.625
E11.6 With other specified complications
0.000 0.379 0.621
H31.9 Disorder of choroid, unspecified
0.000 0.384 0.616
H31.4 Choroidal detachment
0.000 0.384 0.616
H31.2 Hereditary choroidal dystrophy
0.000 0.384 0.616
E10 Insulin-dependent diabetes mellitus
0.000 0.386 0.614
E11.7 With multiple complications
0.000 0.387 0.613
H30 Chorioretinal inflammation
0.000 0.396 0.604
H34.2 Other retinal artery occlusions
0.000 0.411 0.589
H35.7 Separation of retinal layers
0.000 0.423 0.576
E14.1 With ketoacidosis
0.000 0.428 0.572
E10.3 With ophthalmic complications
0.000 0.430 0.570
E11.5 With peripheral circulatory complications
0.000 0.433 0.567
E14.6 With other specified complications
0.000 0.451 0.549
E12 Malnutrition-related diabetes mellitus
0.000 0.454 0.546
E14.8 With unspecified complications
0.000 0.457 0.543
E14.5 With peripheral circulatory complications
0.000 0.461 0.539
E14.7 With multiple complications
0.000 0.465 0.535
E14.0 With coma
0.000 0.465 0.535
E10.8 With unspecified complications
0.000 0.489 0.511
E14.2 Withrenal complications
0.000 0.509 0.490
H32.8 Other chorioretinal disorders in diseases classified elsewhere
0.000 0.512 0.488
H32.0 Chorioretinal inflammation in infectious and parasitic diseases classified elsewhere
0.000 0.512 0.488
E14.4 With neurological complications
0.000 0.517 0.483
E10.0 With coma
0.000 0.528 0.472
E11.0 With coma
0.000 0.535 0.465
E14.9 Without complications
0.000 0.539 0.461
E10.4 With neurological complications
0.000 0.542 0.458
E10.2 With renal complications
0.000 0.543 0.457
E10.7 With multiple complications
0.000 0.560 0.440
H30.8 Other chorioretinal inflammations
0.000 0.567 0.433
H30.2 Posterior cyclitis
0.000 0.567 0.433
H30.1 Disseminated chorioretinal inflammation
0.000 0.567 0.433
H30.0 Focal chorioretinal inflammation
0.000 0.567 0.433
E10.6 With other specified complications
0.000 0.592 0.408
I10 Essential (primary) hypertension
0.405 0.595 0.000
E13 Other specified diabetes mellitus
0.000 0.596 0.403
E10.5 With peripheral circulatory complications
0.000 0.601 0.399
E12.9 Without complications
0.000 0.608 0.392
E12.8 With unspecified complications
0.000 0.608 0.392
E12.7 With multiple complications
0.000 0.608 0.392
E12.6 With other specified complications
0.000 0.608 0.392
E12.5 With peripheral circulatory complications
0.000 0.608 0.392
E12.4 With neurological complications
0.000 0.608 0.392
E12.3 With ophthalmic complications
0.000 0.608 0.392
E12.2 With renal complications
0.000 0.608 0.392
E12.1 With ketoacidosis
0.000 0.608 0.392
E12.0 With coma
0.000 0.608 0.392
H35.6 Retinal haemorrhage
0.000 0.635 0.365
H30.9 Chorioretinal inflammation, unspecified
0.000 0.643 0.356
E10.1 With ketoacidosis
0.000 0.646 0.354
E13.8 With unspecified complications
0.000 0.710 0.289
E13.7 With multiple complications
0.000 0.710 0.289
E13.6 With other specified complications
0.000 0.710 0.289
E13.5 With peripheral circulatory complications
0.000 0.710 0.289
E13.4 With neurological complications
0.000 0.710 0.289
E13.3 With ophthalmic complications
0.000 0.710 0.289
E13.2 With renal complications
0.000 0.710 0.289
E13.1 With ketoacidosis
0.000 0.710 0.289
E13.0 With coma
0.000 0.710 0.289
H33.2 Serous retinal detachment
0.000 0.748 0.252
E13.9 Without complications
0.001 0.853 0.146
E10.9 Without complications
0.000 0.869 0.131
I10-I15 Hypertensive diseases
0.056 0.944 0.000
I13 Hypertensive heart and renal disease
0.040 0.959 0.000
I15 Secondary hypertension
0.034 0.966 0.000
I12 Hypertensive renal disease
0.030 0.970 0.000
I13.9 Hypertensive heart and renal disease, unspecified
0.029 0.971 0.000
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.029 0.971 0.000
I13.1 Hypertensive heart and renal disease with renal failure
0.029 0.971 0.000
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.029 0.971 0.000
Z96.1 Presence of intraocular lens
0.000 0.971 0.029
I11 Hypertensive heart disease
0.027 0.973 0.000
I15.9 Seconday hypertension, unspecified
0.026 0.974 0.000
I15.8 Other secondary hypertension
0.025 0.975 0.000
I15.2 Hypertension secondary to endocrine disorders
0.024 0.976 0.000
R73.9 Hyperglycaemia, unspecified
0.000 0.976 0.024
I12.9 Hypertensive renal disease without renal failure
0.023 0.977 0.000
I15.0 Renovascular hypertension
0.021 0.978 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.980 0.020
Q43 Other congenital malformations of intestine
0.019 0.981 0.000
Q38.7 Pharyngeal pouch
0.018 0.982 0.000
Q43.3 Congenital malformations of intestinal fixation
0.018 0.982 0.000
I15.1 Hypertension secondary to other renal disorders
0.018 0.982 0.000
Q38 Other congenital malformations of tongue, mouth and pharynx
0.018 0.982 0.000
E65-E68 Obesity and other hyperalimentation
0.000 0.982 0.018
Q38-Q45 Other congenital malformations of the digestive system
0.018 0.982 0.000
Q43.9 Congenital malformation of intestine, unspecified
0.017 0.983 0.000
E66 Obesity
0.000 0.983 0.017
I11.0 Hypertensive heart disease with (congestive) heart failure
0.017 0.983 0.000
E66.8 Other obesity
0.000 0.984 0.016
Q43.8 Other specified congenital malformations of intestine
0.015 0.985 0.000
Q43.0 Meckel's diverticulum
0.015 0.985 0.000
D23.6 Skin of upper limb, including shoulder
0.000 0.985 0.015
Q43.7 Persistent cloaca
0.014 0.986 0.000
Q43.6 Congenital fistula of rectum and anus
0.014 0.986 0.000
Q43.5 Ectopic anus
0.014 0.986 0.000
Q43.4 Duplication of intestine
0.014 0.986 0.000
Q43.2 Other congenital functional disorders of colon
0.014 0.986 0.000
E66.9 Obesity, unspecified
0.000 0.986 0.014
Q40 Other congenital malformations of upper alimentary tract
0.014 0.986 0.000
E66.0 Obesity due to excess calories
0.000 0.986 0.014
H92.0 Otalgia
0.014 0.986 0.000
Q43.1 Hirschsprung's disease
0.013 0.986 0.000
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.986 0.013
Q38.8 Other congenital malformations of pharynx
0.013 0.987 0.000
Q38.6 Other congenital malformations of mouth
0.013 0.987 0.000
Q38.5 Congenital malformations of palate, not elsewhere classified
0.013 0.987 0.000
Q38.4 Congenital malformations of salivary glands and ducts
0.013 0.987 0.000
Q38.3 Other congenital malformations of tongue
0.013 0.987 0.000
Q38.2 Macroglossia
0.013 0.987 0.000
Q38.1 Ankyloglossia
0.013 0.987 0.000
Q38.0 Congenital malformations of lips, not elsewhere classified
0.013 0.987 0.000
E67 Other hyperalimentation
0.000 0.987 0.013
E68 Sequelae of hyperalimentation
0.000 0.987 0.013
Q42 Congenital absence, atresia and stenosis of large intestine
0.013 0.987 0.000
Q41 Congenital absence, atresia and stenosis of small intestine
0.013 0.987 0.000
Q39 Congenital malformations of oesophagus
0.013 0.987 0.000
E66.1 Drug-induced obesity
0.000 0.987 0.013
Q45 Other congenital malformations of digestive system
0.013 0.987 0.000
E40-E46 Malnutrition
0.000 0.988 0.012
Q44 Congenital malformations of gallbladder, bile ducts and liver
0.012 0.988 0.000
Q40.1 Congenital hiatus hernia
0.012 0.988 0.000
E27 Other disorders of adrenal gland
0.000 0.988 0.012
E27.9 Disorder of adrenal gland, unspecified
0.000 0.989 0.011
I11.9 Hypertensive heart disease without (congestive) heart failure
0.010 0.989 0.000
E20-E35 Disorders of other endocrine glands
0.000 0.989 0.011
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.989 0.011
M84.1 Nonunion of fracture [pseudarthrosis]
0.000 0.989 0.011
E65 Localised adiposity
0.000 0.989 0.010
M84.13 Nonunion of fracture [pseudarthrosis] (Forearm)
0.000 0.989 0.011
M84.12 Nonunion of fracture [pseudarthrosis] (Upper arm)
0.000 0.990 0.010
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.010 0.990 0.000
Q40.9 Congenital malformation of upper alimentary tract, unspecified
0.010 0.990 0.000
Q40.8 Other specified congenital malformations of upper alimentary tract
0.010 0.990 0.000
Q40.3 Congenital malformation of stomach, unspecified
0.010 0.990 0.000
Q40.0 Congenital hypertrophic pyloric stenosis
0.010 0.990 0.000
E50-E64 Other nutritional deficiencies
0.000 0.990 0.010
Q39.4 Oesophageal web
0.010 0.990 0.000
T39.0 Salicylates
0.010 0.990 0.000
E27.2 Addisonian crisis
0.000 0.990 0.010
Q80-Q89 Other congenital malformations
0.010 0.990 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.990 0.010
Q87 Other specified congenital malformation syndromes affecting multiple systems
0.010 0.990 0.000
E67.8 Other specified hyperalimentation
0.000 0.990 0.009
E67.3 Hypervitaminosis D
0.000 0.990 0.009
E67.2 Megavitamin-B6 syndrome
0.000 0.990 0.009
E67.1 Hypercarotenaemia
0.000 0.990 0.009
E67.0 Hypervitaminosis A
0.000 0.990 0.009
Q41.9 Congenital absence, atresia and stenosis of small intestine, part unspecified
0.009 0.990 0.000
Q41.8 Congenital absence, atresia and stenosis of other specified parts of small intestine
0.009 0.990 0.000
Q41.2 Congenital absence, atresia and stenosis of ileum
0.009 0.990 0.000
Q41.1 Congenital absence, atresia and stenosis of jejunum
0.009 0.990 0.000
Q41.0 Congenital absence, atresia and stenosis of duodenum
0.009 0.990 0.000
Q42.9 Congenital absence, atresia and stenosis of large intestine, part unspecified
0.009 0.990 0.000
Q42.8 Congenital absence, atresia and stenosis of other parts of large intestine
0.009 0.990 0.000
Q42.3 Congenital absence, atresia and stenosis of anus without fistula
0.009 0.990 0.000
Q42.2 Congenital absence, atresia and stenosis of anus with fistula
0.009 0.990 0.000
Q42.1 Congenital absence, atresia and stenosis of rectum without fistula
0.009 0.990 0.000
Q42.0 Congenital absence, atresia and stenosis of rectum with fistula
0.009 0.990 0.000
Q87.4 Marfan's syndrome
0.010 0.990 0.000
Q39.9 Congenital malformation of oesophagus, unspecified
0.009 0.991 0.000
Q39.8 Other congenital malformations of oesophagus
0.009 0.991 0.000
Q39.5 Congenital dilatation of oesophagus
0.009 0.991 0.000
Q39.3 Congenital stenosis and stricture of oesophagus
0.009 0.991 0.000
Q39.2 Congenital tracheooesophageal fistula without atresia
0.009 0.991 0.000
Q39.1 Atresia of oesophagus with tracheooesophageal fistula
0.009 0.991 0.000
Q39.0 Atresia of oesophagus without fistula
0.009 0.991 0.000
Q45.8 Other specified congenital malformations of digestive system
0.009 0.991 0.000
Q45.9 Congenital malformation of digestive system, unspecified
0.009 0.991 0.000
Q45.2 Congenital pancreatic cyst
0.009 0.991 0.000
Q45.1 Annular pancreas
0.009 0.991 0.000
Q45.0 Agenesis, aplasia and hypoplasia of pancreas
0.009 0.991 0.000
E27.8 Other specified disorders of adrenal gland
0.000 0.991 0.009
M84.14 Nonunion of fracture [pseudarthrosis] (Hand)
0.000 0.991 0.009
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)
0.000 0.991 0.009
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.991 0.009
E45 Retarded development following protein-energy malnutrition
0.000 0.991 0.009
E43 Unspecified severe protein-energy malnutrition
0.000 0.991 0.009
E42 Marasmic kwashiorkor
0.000 0.991 0.009
E41 Nutritional marasmus
0.000 0.991 0.009
E40 Kwashiorkor
0.000 0.991 0.009
H92 Otalgia and effusion of ear
0.009 0.991 0.000
Q40.2 Other specified congenital malformations of stomach
0.009 0.991 0.000
Q45.3 Other congenital malformations of pancreas and pancreatic duct
0.009 0.991 0.000
Q44.7 Other congenital malformations of liver
0.009 0.991 0.000
Q44.5 Other congenital malformations of bile ducts
0.009 0.991 0.000
Q44.4 Choledochal cyst
0.009 0.991 0.000
Q44.3 Congenital stenosis and stricture of bile ducts
0.009 0.991 0.000
Q44.2 Atresia of bile ducts
0.009 0.991 0.000
Q44.1 Other congenital malformations of gallbladder
0.009 0.991 0.000
Q44.0 Agenesis, aplasia and hypoplasia of gallbladder
0.009 0.991 0.000
Q27 Other congenital malformations of peripheral vascular system
0.009 0.991 0.000
Q27.9 Congenital malformation of peripheral vascular system, unspecified
0.009 0.991 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.009 0.991 0.000
E34 Other endocrine disorders
0.000 0.991 0.009
M84.16 Nonunion of fracture [pseudarthrosis] (Lower leg)
0.000 0.991 0.009
E27.5 Adrenomedullary hyperfunction
0.000 0.991 0.008
E27.0 Other adrenocortical overactivity
0.000 0.991 0.008
Q20-Q28 Congenital malformations of the circulatory system
0.009 0.991 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.991 0.009
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.009 0.991 0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.008 0.991 0.000
E25 Adrenogenital disorders
0.000 0.992 0.008
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)
0.000 0.992 0.008
Q39.6 Diverticulum of oesophagus
0.008 0.992 0.000
N90.4 Leukoplakia of vulva
0.008 0.992 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.008 0.992 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.008 0.992 0.000
H81.9 Disorder of vestibular function, unspecified
0.008 0.992 0.000
E20 Hypoparathyroidism
0.000 0.992 0.008
T45.1 Antineoplastic and immunosuppressive drugs
0.008 0.992 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.008 0.992 0.000
T46.4 Angiotensin-converting-enzyme inhibitors
0.008 0.992 0.000
Q85 Phakomatoses, not elsewhere classified
0.008 0.992 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.008 0.992 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.008 0.992 0.000
Q83 Congenital malformations of breast
0.008 0.992 0.000
E23 Hypofunction and other disorders of pituitary gland
0.000 0.992 0.008
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.992 0.008
E32 Diseases of thymus
0.000 0.992 0.008
E31 Polyglandular dysfunction
0.000 0.992 0.008
E30 Disorders of puberty, not elsewhere classified
0.000 0.992 0.008
M84.18 Nonunion of fracture [pseudarthrosis] (Other)
0.000 0.992 0.008
Q44.6 Cystic disease of liver
0.008 0.992 0.000
Q28 Other congenital malformations of circulatory system
0.008 0.992 0.000
E34.8 Other specified endocrine disorders
0.000 0.992 0.008
E15 Nondiabetic hypoglycaemic coma
0.000 0.992 0.008
Q87.8 Other specified congenital malformation syndromes, not elsewhere classified
0.008 0.992 0.000
H81 Disorders of vestibular function
0.008 0.992 0.000
E29 Testicular dysfunction
0.000 0.992 0.008
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.008 0.992 0.000
M84.19 Nonunion of fracture [pseudarthrosis] (Site unspecified)
0.000 0.992 0.008
M84.10 Nonunion of fracture [pseudarthrosis] (Multiple sites)
0.000 0.992 0.008
Q35-Q37 Cleft lip and cleft palate
0.008 0.992 0.000
E27.1 Primary adrenocortical insufficiency
0.000 0.992 0.008
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.008 0.992 0.000
Q87.1 Congenital malformation syndromes predominantly associated with short stature
0.008 0.992 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.008 0.992 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.992 0.007
E63 Other nutritional deficiencies
0.000 0.992 0.007
E56 Other vitamin deficiencies
0.000 0.992 0.007
E50 Vitamin A deficiency
0.000 0.992 0.007
E60 Dietary zinc deficiency
0.000 0.992 0.007
E59 Dietary selenium deficiency
0.000 0.992 0.007
E54 Ascorbic acid deficiency
0.000 0.992 0.007
E52 Niacin deficiency [pellagra]
0.000 0.992 0.007
Q27.3 Peripheral arteriovenous malformation
0.008 0.992 0.000
H92.2 Otorrhagia
0.007 0.992 0.000
R73 Elevated blood glucose level
0.000 0.992 0.008
T45.0 Antiallergic and antiemetic drugs
0.007 0.992 0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action
0.007 0.992 0.000
E53 Deficiency of other B group vitamins
0.000 0.992 0.007
T45.5 Anticoagulants
0.007 0.993 0.000
E58 Dietary calcium deficiency
0.000 0.993 0.007
Q86 Congenital malformation syndromes due to known exogenous causes, not elsewhere classified
0.007 0.993 0.000
Q84 Other congenital malformations of integument
0.007 0.993 0.000
Q81 Epidermolysis bullosa
0.007 0.993 0.000
Q80 Congenital ichthyosis
0.007 0.993 0.000
E23.2 Diabetes insipidus
0.000 0.993 0.007
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)
0.000 0.993 0.007
H92.1 Otorrhoea
0.007 0.993 0.000
Q87.5 Other congenital malformation syndromes with other skeletal changes
0.007 0.993 0.000
Q87.3 Congenital malformation syndromes involving early overgrowth
0.007 0.993 0.000
Q87.2 Congenital malformation syndromes predominantly involving limbs
0.007 0.993 0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest
0.007 0.993 0.000
H81.1 Benign paroxysmal vertigo
0.007 0.993 0.000
Q60-Q64 Congenital malformations of the urinary system
0.007 0.993 0.000
Q89 Other congenital malformations, not elsewhere classified
0.007 0.993 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.007 0.993 0.000
E61 Deficiency of other nutrient elements
0.000 0.993 0.007
Q27.8 Other specified congenital malformations of peripheral vascular system
0.007 0.993 0.000
Q68 Other congenital musculoskeletal deformities
0.007 0.993 0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified
0.007 0.993 0.000
Q28.2 Arteriovenous malformation of cerebral vessels
0.007 0.993 0.000
T38.0 Glucocorticoids and synthetic analogues
0.007 0.993 0.000
E51 Thiamine deficiency
0.000 0.993 0.007
Q17 Other congenital malformations of ear
0.007 0.993 0.000
E46 Unspecified protein-energy malnutrition
0.000 0.993 0.007
E26 Hyperaldosteronism
0.000 0.993 0.007
E44.1 Mild protein-energy malnutrition
0.000 0.993 0.006
E44.0 Moderate protein-energy malnutrition
0.000 0.993 0.006
Q28.3 Other malformations of cerebral vessels
0.007 0.993 0.000
Q14 Congenital malformations of posterior segment of eye
0.007 0.993 0.000
Q99 Other chromosome abnormalities, not elsewhere classified
0.007 0.993 0.000
H81.2 Vestibular neuronitis
0.007 0.993 0.000
Q64 Other congenital malformations of urinary system
0.007 0.993 0.000
Q27.4 Congenital phlebectasia
0.007 0.993 0.000
Q27.2 Other congenital malformations of renal artery
0.007 0.993 0.000
Q27.1 Congenital renal artery stenosis
0.007 0.993 0.000
Q27.0 Congenital absence and hypoplasia of umbilical artery
0.007 0.993 0.000
Q85.8 Other phakomatoses, not elsewhere classified
0.007 0.993 0.000
Q83.3 Accessory nipple
0.007 0.993 0.000
Q98 Other sex chromosome abnormalities, male phenotype, not elsewhere classified
0.007 0.993 0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.993 0.006
Q85.9 Phakomatosis, unspecified
0.007 0.993 0.000
T50.8 Diagnostic agents
0.007 0.993 0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system
0.006 0.993 0.000
T46.8 Antivaricose drugs, including sclerosing agents
0.006 0.993 0.000
T46.7 Peripheral vasodilators
0.006 0.993 0.000
E34.5 Androgen resistance syndrome
0.000 0.993 0.006
E34.4 Constitutional tall stature
0.000 0.993 0.006
E34.3 Short stature, not elsewhere classified
0.000 0.993 0.006
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.993 0.006
E34.1 Other hypersecretion of intestinal hormones
0.000 0.993 0.006
Q22 Congenital malformations of pulmonary and tricuspid valves
0.006 0.993 0.000
Q64.3 Other atresia and stenosis of urethra and bladder neck
0.006 0.993 0.000
Q87.0 Congenital malformation syndromes predominantly affecting facial appearance
0.006 0.993 0.000
Q26 Congenital malformations of great veins
0.006 0.994 0.000
Q20 Congenital malformations of cardiac chambers and connexions
0.006 0.994 0.000
T50.4 Drugs affecting uric acid metabolism
0.006 0.994 0.000
I12.0 Hypertensive renal disease with renal failure
0.006 0.994 0.000
Q28.0 Arteriovenous malformation of precerebral vessels
0.006 0.994 0.000
H81.3 Other peripheral vertigo
0.006 0.994 0.000
T45.9 Primarily systemic and haematological agent, unspecified
0.006 0.994 0.000
T45.8 Other primarily systemic and haematological agents
0.006 0.994 0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants
0.006 0.994 0.000
T45.6 Fibrinolysis-affecting drugs
0.006 0.994 0.000
T45.4 Iron and its compounds
0.006 0.994 0.000
T45.3 Enzymes, not elsewhere classified
0.006 0.994 0.000
T46.3 Coronary vasodilators, not elsewhere classified
0.006 0.994 0.000
E28 Ovarian dysfunction
0.000 0.994 0.006
Q76 Congenital malformations of spine and bony thorax
0.006 0.994 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.006 0.994 0.000
Q83.1 Accessory breast
0.006 0.994 0.000
Q18 Other congenital malformations of face and neck
0.006 0.994 0.000
Q67.5 Congenital deformity of spine
0.006 0.994 0.000
T46.5 Other antihypertensive drugs, not elsewhere classified
0.006 0.994 0.000
E25.9 Adrenogenital disorder, unspecified
0.000 0.994 0.006
E25.8 Other adrenogenital disorders
0.000 0.994 0.006
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.006 0.994 0.000
T38.1 Thyroid hormones and substitutes
0.006 0.994 0.000
E34.9 Endocrine disorder, unspecified
0.000 0.994 0.006
E20.9 Hypoparathyroidism, unspecified
0.000 0.994 0.006
H81.8 Other disorders of vestibular function
0.006 0.994 0.000
H83.0 Labyrinthitis
0.006 0.994 0.000
Q37 Cleft palate with cleft lip
0.006 0.994 0.000
Q67.4 Other congenital deformities of skull, face and jaw
0.006 0.994 0.000
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine
0.006 0.994 0.000
Q75 Other congenital malformations of skull and face bones
0.006 0.994 0.000
Q73 Reduction defects of unspecified limb
0.006 0.994 0.000
Q72 Reduction defects of lower limb
0.006 0.994 0.000
Q71 Reduction defects of upper limb
0.006 0.994 0.000
Q70 Syndactyly
0.006 0.994 0.000
Q69 Polydactyly
0.006 0.994 0.000
Q97 Other sex chromosome abnormalities, female phenotype, not elsewhere classified
0.006 0.994 0.000
Q95 Balanced rearrangements and structural markers, not elsewhere classified
0.006 0.994 0.000
Q93 Monosomies and deletions from the autosomes, not elsewhere classified
0.006 0.994 0.000
Q92 Other trisomies and partial trisomies of the autosomes, not elsewhere classified
0.006 0.994 0.000
Q91 Edwards' syndrome and Patau's syndrome
0.006 0.994 0.000
Q00-Q07 Congenital malformations of the nervous system
0.006 0.994 0.000
E20.8 Other hypoparathyroidism
0.000 0.994 0.006
E20.1 Pseudohypoparathyroidism
0.000 0.994 0.006
E20.0 Idiopathic hypoparathyroidism
0.000 0.994 0.006
E24 Cushing's syndrome
0.000 0.994 0.006
Q25 Congenital malformations of great arteries
0.006 0.994 0.000
Q16 Congenital malformations of ear causing impairment of hearing
0.006 0.994 0.000
Q13 Congenital malformations of anterior segment of eye
0.006 0.994 0.000
Q11 Anophthalmos, microphthalmos and macrophthalmos
0.006 0.994 0.000
Q65 Congenital deformities of hip
0.006 0.994 0.000
Q68.8 Other specified congenital musculoskeletal deformities
0.006 0.994 0.000
Q85.1 Tuberous sclerosis
0.006 0.994 0.000
T38.9 Other and unspecified hormone antagonists
0.006 0.994 0.000
T38.8 Other and unspecified hormones and their synthetic substitutes
0.006 0.994 0.000
T38.7 Androgens and anabolic congeners
0.006 0.994 0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified
0.006 0.994 0.000
T38.5 Other oestrogens and progestogens
0.006 0.994 0.000
T38.4 Oral contraceptives
0.006 0.994 0.000
T38.2 Antithyroid drugs
0.006 0.994 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.006 0.994 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.006 0.994 0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.994 0.006
E23.1 Drug-induced hypopituitarism
0.000 0.994 0.006
Q83.9 Congenital malformation of breast, unspecified
0.006 0.994 0.000
Q83.2 Absent nipple
0.006 0.994 0.000
Q83.0 Congenital absence of breast with absent nipple
0.006 0.994 0.000
E30.9 Disorder of puberty, unspecified
0.000 0.994 0.006
E30.8 Other disorders of puberty
0.000 0.994 0.006
E30.1 Precocious puberty
0.000 0.994 0.006
E30.0 Delayed puberty
0.000 0.994 0.006
E31.9 Polyglandular dysfunction, unspecified
0.000 0.994 0.006
E31.8 Other polyglandular dysfunction
0.000 0.994 0.006
E31.1 Polyglandular hyperfunction
0.000 0.994 0.006
E31.0 Autoimmune polyglandular failure
0.000 0.994 0.006
E32.9 Disease of thymus, unspecified
0.000 0.994 0.006
E32.8 Other diseases of thymus
0.000 0.994 0.006
E32.1 Abscess of thymus
0.000 0.994 0.006
E32.0 Persistent hyperplasia of thymus
0.000 0.994 0.006
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.994 0.006
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.994 0.006
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.994 0.006
Q28.9 Congenital malformation of circulatory system, unspecified
0.006 0.994 0.000
Q28.8 Other specified congenital malformations of circulatory system
0.006 0.994 0.000
Q28.1 Other malformations of precerebral vessels
0.006 0.994 0.000
Q82 Other congenital malformations of skin
0.006 0.994 0.000
H81.4 Vertigo of central origin
0.006 0.994 0.000
Q15 Other congenital malformations of eye
0.006 0.994 0.000
E29.9 Testicular dysfunction, unspecified
0.000 0.994 0.006
E29.8 Other testicular dysfunction
0.000 0.994 0.006
E29.0 Testicular hyperfunction
0.000 0.994 0.006
T39.4 Antirheumatics, not elsewhere classified
0.006 0.994 0.000
T39.2 Pyrazolone derivatives
0.006 0.994 0.000
E55 Vitamin D deficiency
0.000 0.994 0.006
Q83.8 Other congenital malformations of breast
0.006 0.994 0.000
Q36 Cleft lip
0.006 0.994 0.000
Q66 Congenital deformities of feet
0.006 0.994 0.000
Q17.5 Prominent ear
0.006 0.994 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.006 0.994 0.000
E23.6 Other disorders of pituitary gland
0.000 0.994 0.006
Q10 Congenital malformations of eyelid, lachrymal apparatus and orbit
0.006 0.994 0.000
Q90 Down's syndrome
0.006 0.994 0.000
Q35 Cleft palate
0.006 0.994 0.000
Q14.1 Congenital malformation of retina
0.006 0.994 0.000
Q34 Other congenital malformations of respiratory system
0.006 0.994 0.000
Q33 Congenital malformations of lung
0.006 0.994 0.000
Q32 Congenital malformations of trachea and bronchus
0.006 0.994 0.000
Q31 Congenital malformations of larynx
0.006 0.994 0.000
Q30 Congenital malformations of nose
0.006 0.994 0.000
Q96 Turner's syndrome
0.006 0.994 0.000
H83 Other diseases of inner ear
0.006 0.994 0.000
T36 Poisoning by systemic antibiotics
0.006 0.994 0.000
H81.0 Meniere's disease
0.006 0.994 0.000
T39.1 4-Aminophenol derivatives
0.006 0.994 0.000
E29.1 Testicular hypofunction
0.000 0.994 0.006
E50.9 Vitamin A deficiency, unspecified
0.000 0.994 0.005
E50.8 Other manifestations of vitamin A deficiency
0.000 0.994 0.005
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.994 0.005
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.994 0.005
E50.5 Vitamin A deficiency with night blindness
0.000 0.994 0.005
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.994 0.005
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.994 0.005
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.994 0.005
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.994 0.005
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.994 0.005
E56.9 Vitamin deficiency, unspecified
0.000 0.994 0.005
E56.8 Deficiency of other vitamins
0.000 0.994 0.005
E56.1 Deficiency of vitamin K
0.000 0.994 0.005
E56.0 Deficiency of vitamin E
0.000 0.994 0.005
E63.9 Nutritional deficiency, unspecified
0.000 0.994 0.005
E63.8 Other specified nutritional deficiencies
0.000 0.994 0.005
E63.1 Imbalance of constituents of food intake
0.000 0.994 0.005
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.994 0.005
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.994 0.005
E64.8 Sequelae of other nutritional deficiencies
0.000 0.994 0.005
E64.3 Sequelae of rickets
0.000 0.994 0.005
E64.2 Sequelae of vitamin C deficiency
0.000 0.994 0.005
E64.1 Sequelae of vitamin A deficiency
0.000 0.994 0.005
E64.0 Sequelae of protein-energy malnutrition
0.000 0.994 0.005
Q18.0 Sinus, fistula and cyst of branchial cleft
0.006 0.994 0.000
E53.9 Vitamin B deficiency, unspecified
0.000 0.994 0.006
Q99.8 Other specified chromosome abnormalities
0.006 0.994 0.000
Q76.5 Cervical rib
0.006 0.994 0.000
E34.0 Carcinoid syndrome
0.000 0.994 0.005
E53.1 Pyridoxine deficiency
0.000 0.994 0.005
E53.0 Riboflavin deficiency
0.000 0.994 0.005
T45.2 Vitamins, not elsewhere classified
0.005 0.994 0.000
Q74 Other congenital malformations of limb(s)
0.005 0.994 0.000
H80-H83 Diseases of inner ear
0.006 0.994 0.000
T46.1 Calcium-channel blockers
0.005 0.994 0.000
Q80.9 Congenital ichthyosis, unspecified
0.005 0.994 0.000
Q80.8 Other congenital ichthyosis
0.005 0.994 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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