TreeWAS – Variant ID: rs10895001

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I10 Essential (primary) hypertension	0.000	0.000	1.000
I10-I15 Hypertensive diseases	0.000	0.817	0.183
I11 Hypertensive heart disease	0.000	0.853	0.146
I13 Hypertensive heart and renal disease	0.000	0.877	0.123
I11.9 Hypertensive heart disease without (congestive) heart failure	0.000	0.883	0.117
I11.0 Hypertensive heart disease with (congestive) heart failure	0.000	0.891	0.109
I15 Secondary hypertension	0.000	0.900	0.100
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure	0.000	0.911	0.088
I13.1 Hypertensive heart and renal disease with renal failure	0.000	0.911	0.088
I13.0 Hypertensive heart and renal disease with (congestive) heart failure	0.000	0.911	0.088
I13.9 Hypertensive heart and renal disease, unspecified	0.000	0.920	0.080
I15.8 Other secondary hypertension	0.000	0.928	0.072
I15.0 Renovascular hypertension	0.000	0.928	0.072
I15.9 Seconday hypertension, unspecified	0.000	0.930	0.070
I15.2 Hypertension secondary to endocrine disorders	0.000	0.936	0.063
I15.1 Hypertension secondary to other renal disorders	0.000	0.942	0.058
I12 Hypertensive renal disease	0.000	0.942	0.058
I12.9 Hypertensive renal disease without renal failure	0.000	0.972	0.028
N31.9 Neuromuscular dysfunction of bladder, unspecified	0.000	0.978	0.022
N31.8 Other neuromuscular dysfunction of bladder	0.000	0.980	0.020
N31 Neuromuscular dysfunction of bladder, not elsewhere classified	0.000	0.980	0.020
I60.9 Subarachnoid haemorrhage, unspecified	0.017	0.983	0.000
N31.2 Flaccid neuropathic bladder, not elsewhere classified	0.000	0.984	0.016
N31.1 Reflex neuropathic bladder, not elsewhere classified	0.000	0.985	0.015
N31.0 Uninhibited neuropathic bladder, not elsewhere classified	0.000	0.985	0.014
Z40.0 Prophylactic surgery for risk-factors related to malignant neoplasms	0.010	0.990	0.000
R44.1 Visual hallucinations	0.000	0.991	0.009
I12.0 Hypertensive renal disease with renal failure	0.000	0.991	0.009
I25.1 Atherosclerotic heart disease	0.000	0.992	0.008
M24.26 Disorder of ligament (Lower leg)	0.008	0.992	0.000
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium	0.000	0.992	0.008
M24.2 Disorder of ligament	0.008	0.992	0.000
K74.3 Primary biliary cirrhosis	0.008	0.992	0.000
M24.24 Disorder of ligament (Hand)	0.008	0.992	0.000
M24.23 Disorder of ligament (Forearm)	0.007	0.993	0.000
M24.27 Disorder of ligament (Ankle and foot)	0.007	0.993	0.000
M13.96 Arthritis, unspecified (Lower leg)	0.007	0.993	0.000
A40.3 Septicaemia due to Streptococcus pneumoniae	0.006	0.994	0.000
M13.97 Arthritis, unspecified (Ankle and foot)	0.006	0.994	0.000
R44 Other symptoms and signs involving general sensations and perceptions	0.000	0.994	0.006
M24.29 Disorder of ligament (Site unspecified)	0.006	0.994	0.000
M24.25 Disorder of ligament (Pelvic region and thigh)	0.006	0.994	0.000
M24.22 Disorder of ligament (Upper arm)	0.006	0.994	0.000
M24.20 Disorder of ligament (Multiple sites)	0.006	0.994	0.000
M46.96 Inflammatory spondylopathy, unspecified (Lumbar region)	0.006	0.994	0.000
Q05.9 Spina bifida, unspecified	0.006	0.994	0.000
M24.28 Disorder of ligament (Other)	0.006	0.994	0.000
Q05 Spina bifida	0.006	0.994	0.000
Q00-Q07 Congenital malformations of the nervous system	0.005	0.995	0.000
Q76 Congenital malformations of spine and bony thorax	0.005	0.995	0.000
Q76.0 Spina bifida occulta	0.005	0.995	0.000
M24 Other specific joint derangements	0.005	0.995	0.000
R44.3 Hallucinations, unspecified	0.000	0.995	0.005
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.005	0.995	0.000
M24.6 Ankylosis of joint	0.005	0.995	0.000
R44.0 Auditory hallucinations	0.000	0.995	0.005
Q07 Other congenital malformations of nervous system	0.005	0.995	0.000
K11.5 Sialolithiasis	0.000	0.995	0.005
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.005	0.995	0.000
M24.66 Ankylosis of joint (Lower leg)	0.005	0.995	0.000
Q76.4 Other congenital malformations of spine, not associated with scoliosis	0.005	0.995	0.000
Q05.4 Unspecified spina bifida with hydrocephalus	0.005	0.995	0.000
R44.2 Other hallucinations	0.000	0.995	0.005
M72.27 Plantar fascial fibromatosis-Ankle/Foot	0.005	0.995	0.000
Q07.0 Arnold-Chiari syndrome	0.005	0.995	0.000
M24.8 Other specific joint derangements, not elsewhere classified	0.005	0.995	0.000
M24.0 Loose body in joint	0.005	0.995	0.000
M46.9 Inflammatory spondylopathy, unspecified	0.005	0.995	0.000
R44.8 Other and unspecified symptoms and signs involving general sensations and perceptions	0.000	0.995	0.005
Q50-Q56 Congenital malformations of genital organs	0.005	0.995	0.000
A40.8 Other streptococcal septicaemia	0.004	0.996	0.000
Q54 Hypospadias	0.004	0.996	0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.004	0.996	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.004	0.996	0.000
M24.7 Protrusio acetabuli	0.004	0.996	0.000
Q05.8 Sacral spina bifida without hydrocephalus	0.004	0.996	0.000
Q05.7 Lumbar spina bifida without hydrocephalus	0.004	0.996	0.000
Q05.6 Thoracic spina bifida without hydrocephalus	0.004	0.996	0.000
Q05.5 Cervical spina bifida without hydrocephalus	0.004	0.996	0.000
Q05.3 Sacral spina bifida with hydrocephalus	0.004	0.996	0.000
Q05.2 Lumbar spina bifida with hydrocephalus	0.004	0.996	0.000
Q05.1 Thoracic spina bifida with hydrocephalus	0.004	0.996	0.000
Q05.0 Cervical spina bifida with hydrocephalus	0.004	0.996	0.000
A40 Streptococcal septicaemia	0.004	0.996	0.000
M24.87 Other specific joint derangements, not elsewhere classified (Ankle and foot)	0.004	0.996	0.000
M46.4 Discitis, unspecified	0.004	0.996	0.000
Q18 Other congenital malformations of face and neck	0.004	0.996	0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified	0.004	0.996	0.000
Q18.1 Preauricular sinus and cyst	0.004	0.996	0.000
Q54.9 Hypospadias, unspecified	0.004	0.996	0.000
Q65 Congenital deformities of hip	0.004	0.996	0.000
M24.21 Disorder of ligament (Shoulder region)	0.004	0.996	0.000
A48.1 Legionnaires' disease	0.004	0.996	0.000
Q76.1 Klippel-Feil syndrome	0.004	0.996	0.000
Q06 Other congenital malformations of spinal cord	0.004	0.996	0.000
Q01 Encephalocele	0.004	0.996	0.000
Q00 Anencephaly and similar malformations	0.004	0.996	0.000
Q02 Microcephaly	0.004	0.996	0.000
Q68 Other congenital musculoskeletal deformities	0.004	0.996	0.000
Q76.9 Congenital malformation of bony thorax, unspecified	0.004	0.996	0.000
Q76.8 Other congenital malformations of bony thorax	0.004	0.996	0.000
Q76.7 Congenital malformation of sternum	0.004	0.996	0.000
Q76.6 Other congenital malformations of ribs	0.004	0.996	0.000
Q76.3 Congenital scoliosis due to congenital bony malformation	0.004	0.996	0.000
Q76.2 Congenital spondylolisthesis	0.004	0.996	0.000
Q52 Other congenital malformations of female genitalia	0.004	0.996	0.000
N28.8 Other specified disorders of kidney and ureter	0.004	0.996	0.000
Q04 Other congenital malformations of brain	0.004	0.996	0.000
M24.03 Loose body in joint (Forearm)	0.004	0.996	0.000
M24.67 Ankylosis of joint (Ankle and foot)	0.004	0.996	0.000
M46.90 Inflammatory spondylopathy, unspecified (Multiple sites in spine)	0.004	0.996	0.000
M46.98 Inflammatory spondylopathy, unspecified (Sacral and sacrococcygeal region)	0.004	0.996	0.000
Q76.5 Cervical rib	0.004	0.996	0.000
M24.83 Other specific joint derangements, not elsewhere classified (Forearm)	0.004	0.996	0.000
M24.9 Joint derangement, unspecified	0.004	0.996	0.000
Z90.2 Acquired absence of lung [part of]	0.000	0.996	0.004
M46 Other inflammatory spondylopathies	0.004	0.996	0.000
M24.64 Ankylosis of joint (Hand)	0.004	0.996	0.000
M24.02 Loose body in joint (Upper arm)	0.004	0.996	0.000
M24.5 Contracture of joint	0.004	0.996	0.000
H66.9 Otitis media, unspecified	0.004	0.996	0.000
Q03 Congenital hydrocephalus	0.004	0.996	0.000
Q53 Undescended testicle	0.004	0.996	0.000
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine	0.004	0.996	0.000
Q75 Other congenital malformations of skull and face bones	0.004	0.996	0.000
Q73 Reduction defects of unspecified limb	0.004	0.996	0.000
Q72 Reduction defects of lower limb	0.004	0.996	0.000
Q71 Reduction defects of upper limb	0.004	0.996	0.000
Q70 Syndactyly	0.004	0.996	0.000
Q69 Polydactyly	0.004	0.996	0.000
M24.05 Loose body in joint (Pelvic region and thigh)	0.004	0.996	0.000
Q67.4 Other congenital deformities of skull, face and jaw	0.004	0.996	0.000
K57.1 Diverticular disease of small intestine without perforation or abscess	0.004	0.996	0.000
I60 Subarachnoid haemorrhage	0.004	0.996	0.000
M24.69 Ankylosis of joint (Site unspecified)	0.004	0.996	0.000
M24.68 Ankylosis of joint (Other)	0.004	0.996	0.000
M24.65 Ankylosis of joint (Pelvic region and thigh)	0.004	0.996	0.000
M24.63 Ankylosis of joint (Forearm)	0.004	0.996	0.000
M24.62 Ankylosis of joint (Upper arm)	0.004	0.996	0.000
M24.61 Ankylosis of joint (Shoulder region)	0.004	0.996	0.000
M24.60 Ankylosis of joint (Multiple sites)	0.004	0.996	0.000
Q35-Q37 Cleft lip and cleft palate	0.004	0.996	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.004	0.996	0.000
Q80-Q89 Other congenital malformations	0.004	0.996	0.000
Q07.9 Congenital malformation of nervous system, unspecified	0.004	0.996	0.000
Q07.8 Other specified congenital malformations of nervous system	0.004	0.996	0.000
Q66 Congenital deformities of feet	0.004	0.996	0.000
M24.86 Other specific joint derangements, not elsewhere classified (Lower leg)	0.004	0.996	0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified	0.004	0.996	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.004	0.996	0.000
M46.46 Discitis, unspecified (Lumbar region)	0.004	0.996	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.004	0.996	0.000
A48 Other bacterial diseases, not elsewhere classified	0.004	0.996	0.000
M24.04 Loose body in joint (Hand)	0.004	0.996	0.000
A49.8 Other bacterial infections of unspecified site	0.004	0.996	0.000
M46.44 Discitis, unspecified (Thoracic region)	0.004	0.996	0.000
Q52.5 Fusion of labia	0.004	0.996	0.000
Q78 Other osteochondrodysplasias	0.004	0.996	0.000
M24.75 Protrusio acetabuli-Pelvic/thigh	0.004	0.996	0.000
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation	0.004	0.996	0.000
Q83 Congenital malformations of breast	0.004	0.996	0.000
M24.81 Other specific joint derangements, not elsewhere classified (Shoulder region)	0.004	0.996	0.000
M24.89 Other specific joint derangements, not elsewhere classified (Site unspecified)	0.003	0.996	0.000
M24.80 Other specific joint derangements, not elsewhere classified (Multiple sites)	0.003	0.996	0.000
Q54.1 Hypospadias, penile	0.004	0.996	0.000
A48.8 Other specified bacterial diseases	0.004	0.996	0.000
M24.09 Loose body in joint (Site unspecified)	0.003	0.996	0.000
M24.08 Loose body in joint (Other)	0.003	0.996	0.000
M24.06 Loose body in joint-Lower leg	0.003	0.996	0.000
M24.00 Loose body in joint (Multiple sites)	0.003	0.996	0.000
M46.95 Inflammatory spondylopathy, unspecified (Thoracolumbar region)	0.003	0.996	0.000
M46.94 Inflammatory spondylopathy, unspecified (Thoracic region)	0.003	0.996	0.000
M46.93 Inflammatory spondylopathy, unspecified (Cervicothoracic region)	0.003	0.996	0.000
M46.91 Inflammatory spondylopathy, unspecified (Occipito-atlanto-axial region)	0.003	0.996	0.000
Q53.2 Undescended testicle, bilateral	0.003	0.996	0.000
Q11 Anophthalmos, microphthalmos and macrophthalmos	0.003	0.996	0.000
Q56 Indeterminate sex and pseudohermaphroditism	0.003	0.996	0.000
F32.1 Moderate depressive episode	0.004	0.996	0.000
M24.55 Contracture of joint (Pelvic region and thigh)	0.003	0.996	0.000
M24.88 Other specific joint derangements, not elsewhere classified (Other)	0.003	0.996	0.000
M46.42 Discitis, unspecified (Cervical region)	0.003	0.996	0.000
Q74 Other congenital malformations of limb(s)	0.003	0.996	0.000
M24.82 Other specific joint derangements, not elsewhere classified (Upper arm)	0.003	0.996	0.000
Q54.0 Hypospadias, balanic	0.003	0.996	0.000
M24.56 Contracture of joint (Lower leg)	0.003	0.996	0.000
Q65.8 Other congenital deformities of hip	0.003	0.996	0.000
M23.21 Derangement of meniscus due to old tear or injury (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.003	0.997	0.000
M24.84 Other specific joint derangements, not elsewhere classified (Hand)	0.003	0.997	0.000
M46.49 Discitis, unspecified (Site unspecified)	0.003	0.997	0.000
Q68.8 Other specified congenital musculoskeletal deformities	0.003	0.997	0.000
M24.37 Pathological dislocation and subluxation of joint, not elsewhere classified (Ankle and foot)	0.003	0.997	0.000
M46.47 Discitis, unspecified (Lumbosacral region)	0.003	0.997	0.000
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified	0.003	0.997	0.000
M46.0 Spinal enthesopathy	0.003	0.997	0.000
Q52.4 Other congenital malformations of vagina	0.003	0.997	0.000
Q54.8 Other hypospadias	0.003	0.997	0.000
Q54.4 Congenital chordee	0.003	0.997	0.000
Q54.3 Hypospadias, perineal	0.003	0.997	0.000
Q54.2 Hypospadias, penoscrotal	0.003	0.997	0.000
A49 Bacterial infection of unspecified site	0.003	0.997	0.000
A49.0 Staphylococcal infection, unspecified	0.003	0.997	0.000
Q67.8 Other congenital deformities of chest	0.003	0.997	0.000
Q67.7 Pectus carinatum	0.003	0.997	0.000
Q67.3 Plagiocephaly	0.003	0.997	0.000
Q67.2 Dolichocephaly	0.003	0.997	0.000
Q67.1 Compression facies	0.003	0.997	0.000
Q67.0 Facial asymmetry	0.003	0.997	0.000
Q40 Other congenital malformations of upper alimentary tract	0.003	0.997	0.000
Q18.0 Sinus, fistula and cyst of branchial cleft	0.003	0.997	0.000
Q16 Congenital malformations of ear causing impairment of hearing	0.003	0.997	0.000
Q13 Congenital malformations of anterior segment of eye	0.003	0.997	0.000
Q55 Other congenital malformations of male genital organs	0.003	0.997	0.000
M24.79 Protrusio acetabuli-Site unspec	0.003	0.997	0.000
M24.78 Protrusio acetabuli-Other	0.003	0.997	0.000
M24.77 Protrusio acetabuli-Ankle/foot	0.003	0.997	0.000
M24.76 Protrusio acetabuli-Lower leg	0.003	0.997	0.000
M24.74 Protrusio acetabuli-Hand	0.003	0.997	0.000
M24.73 Protrusio acetabuli-Forearm	0.003	0.997	0.000
M24.72 Protrusio acetabuli-Upper arm	0.003	0.997	0.000
M24.71 Protrusio acetabuli-Shldr region	0.003	0.997	0.000
M24.70 Protrusio acetabuli-Mult sites	0.003	0.997	0.000
Q82 Other congenital malformations of skin	0.003	0.997	0.000
A40.2 Septicaemia due to streptococcus, group D	0.003	0.997	0.000
Q83.8 Other congenital malformations of breast	0.003	0.997	0.000
M46.2 Osteomyelitis of vertebra	0.003	0.997	0.000
M46.1 Sacro-iliitis, not elsewhere classified	0.003	0.997	0.000
Q67.6 Pectus excavatum	0.003	0.997	0.000
Q67.5 Congenital deformity of spine	0.003	0.997	0.000
Q15 Other congenital malformations of eye	0.003	0.997	0.000
D73.5 Infarction of spleen	0.000	0.997	0.003
Q12 Congenital lens malformations	0.003	0.997	0.000
M46.48 Discitis, unspecified (Sacral and sacrococcygeal region)	0.003	0.997	0.000
M46.45 Discitis, unspecified (Thoracolumbar region)	0.003	0.997	0.000
M46.43 Discitis, unspecified (Cervicothoracic region)	0.003	0.997	0.000
M46.41 Discitis, unspecified (Occipito-atlanto-axial region)	0.003	0.997	0.000
M46.40 Discitis, unspecified (Multiple sites in spine)	0.003	0.997	0.000
Q14 Congenital malformations of posterior segment of eye	0.003	0.997	0.000
K11.1 Hypertrophy of salivary gland	0.000	0.997	0.003
Q18.9 Congenital malformation of face and neck, unspecified	0.003	0.997	0.000
Q18.8 Other specified congenital malformations of face and neck	0.003	0.997	0.000
Q18.7 Microcheilia	0.003	0.997	0.000
Q18.6 Macrocheilia	0.003	0.997	0.000
Q18.5 Microstomia	0.003	0.997	0.000
Q18.4 Macrostomia	0.003	0.997	0.000
Q18.3 Webbing of neck	0.003	0.997	0.000
Q18.2 Other branchial cleft malformations	0.003	0.997	0.000
M24.39 Pathological dislocation and subluxation of joint, not elsewhere classified (Site unspecified)	0.003	0.997	0.000
M24.38 Pathological dislocation and subluxation of joint, not elsewhere classified (Other)	0.003	0.997	0.000
M24.36 Pathological dislocation and subluxation of joint, not elsewhere classified (Lower leg)	0.003	0.997	0.000
M24.35 Pathological dislocation and subluxation of joint, not elsewhere classified (Pelvic region and thigh)	0.003	0.997	0.000
M24.34 Pathological dislocation and subluxation of joint, not elsewhere classified (Hand)	0.003	0.997	0.000
M24.33 Pathological dislocation and subluxation of joint, not elsewhere classified (Forearm)	0.003	0.997	0.000
M24.32 Pathological dislocation and subluxation of joint, not elsewhere classified (Upper arm)	0.003	0.997	0.000
M24.31 Pathological dislocation and subluxation of joint, not elsewhere classified (Shoulder region)	0.003	0.997	0.000
M24.30 Pathological dislocation and subluxation of joint, not elsewhere classified (Multiple sites)	0.003	0.997	0.000
M46.99 Inflammatory spondylopathy, unspecified (Site unspecified)	0.003	0.997	0.000
Q66.6 Other congenital valgus deformities of feet	0.003	0.997	0.000
Q10 Congenital malformations of eyelid, lachrymal apparatus and orbit	0.003	0.997	0.000
Q65.9 Congenital deformity of hip, unspecified	0.003	0.997	0.000
Q65.6 Unstable hip	0.003	0.997	0.000
Q65.5 Congenital subluxation of hip, unspecified	0.003	0.997	0.000
Q65.4 Congenital subluxation of hip, bilateral	0.003	0.997	0.000
Q65.3 Congenital subluxation of hip, unilateral	0.003	0.997	0.000
Q65.2 Congenital dislocation of hip, unspecified	0.003	0.997	0.000
Q65.1 Congenital dislocation of hip, bilateral	0.003	0.997	0.000
Q65.0 Congenital dislocation of hip, unilateral	0.003	0.997	0.000
M46.97 Inflammatory spondylopathy, unspecified (Lumbosacral region)	0.003	0.997	0.000
Q00.2 Iniencephaly	0.003	0.997	0.000
Q00.1 Craniorachischisis	0.003	0.997	0.000
Q00.0 Anencephaly	0.003	0.997	0.000
Q01.9 Encephalocele, unspecified	0.003	0.997	0.000
Q01.8 Encephalocele of other sites	0.003	0.997	0.000
Q01.2 Occipital encephalocele	0.003	0.997	0.000
Q01.1 Nasofrontal encephalocele	0.003	0.997	0.000
Q01.0 Frontal encephalocele	0.003	0.997	0.000
Q06.9 Congenital malformation of spinal cord, unspecified	0.003	0.997	0.000
Q06.8 Other specified congenital malformations of spinal cord	0.003	0.997	0.000
Q06.4 Hydromyelia	0.003	0.997	0.000
Q06.3 Other congenital cauda equina malformations	0.003	0.997	0.000
Q06.2 Diastematomyelia	0.003	0.997	0.000
Q06.1 Hypoplasia and dysplasia of spinal cord	0.003	0.997	0.000
Q06.0 Amyelia	0.003	0.997	0.000
Q52.9 Congenital malformation of female genitalia, unspecified	0.003	0.997	0.000
Q52.8 Other specified congenital malformations of female genitalia	0.003	0.997	0.000
Q52.7 Other congenital malformations of vulva	0.003	0.997	0.000
Q52.6 Congenital malformation of clitoris	0.003	0.997	0.000
Q52.3 Imperforate hymen	0.003	0.997	0.000
Q52.2 Congenital rectovaginal fistula	0.003	0.997	0.000
Q52.1 Doubling of vagina	0.003	0.997	0.000
Q52.0 Congenital absence of vagina	0.003	0.997	0.000
Q68.5 Congenital bowing of long bones of leg, unspecified	0.003	0.997	0.000
Q68.4 Congenital bowing of tibia and fibula	0.003	0.997	0.000
Q68.3 Congenital bowing of femur	0.003	0.997	0.000
Q68.2 Congenital deformity of knee	0.003	0.997	0.000
Q68.1 Congenital deformity of hand	0.003	0.997	0.000
Q68.0 Congenital deformity of sternocleidomastoid muscle	0.003	0.997	0.000
Q45 Other congenital malformations of digestive system	0.003	0.997	0.000
M46.3 Infection of intervertebral disk (pyogenic)	0.003	0.997	0.000
Q04.9 Congenital malformation of brain, unspecified	0.003	0.997	0.000
Q04.8 Other specified congenital malformations of brain	0.003	0.997	0.000
Q04.5 Megalencephaly	0.003	0.997	0.000
Q04.4 Septo-optic dysplasia	0.003	0.997	0.000
Q04.3 Other reduction deformities of brain	0.003	0.997	0.000
Q04.2 Holoprosencephaly	0.003	0.997	0.000
Q04.1 Arhinencephaly	0.003	0.997	0.000
Q04.0 Congenital malformations of corpus callosum	0.003	0.997	0.000
Q66.7 Pes cavus	0.003	0.997	0.000
M24.57 Contracture of joint (Ankle and foot)	0.003	0.997	0.000
Q31 Congenital malformations of larynx	0.003	0.997	0.000
Q99 Other chromosome abnormalities, not elsewhere classified	0.003	0.997	0.000
Q60-Q64 Congenital malformations of the urinary system	0.003	0.997	0.000
I60.3 Subarachnoid haemorrhage from posterior communicating artery	0.003	0.997	0.000
Q66.3 Other congenital varus deformities of feet	0.003	0.997	0.000
Q51 Congenital malformations of uterus and cervix	0.003	0.997	0.000
A40.0 Septicaemia due to streptococcus, group A	0.003	0.997	0.000
Q04.6 Congenital cerebral cysts	0.003	0.997	0.000
M24.01 Loose body in joint (Shoulder region)	0.003	0.997	0.000
M24.52 Contracture of joint (Upper arm)	0.003	0.997	0.000
M24.99 Joint derangement, unspecified (Site unspecified)	0.003	0.997	0.000
M24.98 Joint derangement, unspecified (Other)	0.003	0.997	0.000
M24.97 Joint derangement, unspecified (Ankle and foot)	0.003	0.997	0.000
M24.96 Joint derangement, unspecified (Lower leg)	0.003	0.997	0.000
M24.95 Joint derangement, unspecified (Pelvic region and thigh)	0.003	0.997	0.000
M24.94 Joint derangement, unspecified (Hand)	0.003	0.997	0.000
M24.93 Joint derangement, unspecified (Forearm)	0.003	0.997	0.000
M24.92 Joint derangement, unspecified (Upper arm)	0.003	0.997	0.000
M24.91 Joint derangement, unspecified (Shoulder region)	0.003	0.997	0.000
M24.90 Joint derangement, unspecified (Multiple sites)	0.003	0.997	0.000
M46.8 Other specified inflammatory spondylopathies	0.003	0.997	0.000
M46.5 Other infective spondylopathies	0.003	0.997	0.000
Q79.8 Other congenital malformations of musculoskeletal system	0.003	0.997	0.000
Q83.1 Accessory breast	0.003	0.997	0.000
Q37 Cleft palate with cleft lip	0.003	0.997	0.000
M24.59 Contracture of joint (Site unspecified)	0.003	0.997	0.000
M24.58 Contracture of joint (Other)	0.003	0.997	0.000
M24.53 Contracture of joint (Forearm)	0.003	0.997	0.000
M24.50 Contracture of joint (Multiple sites)	0.003	0.997	0.000
Q17 Other congenital malformations of ear	0.003	0.997	0.000
Q03.9 Congenital hydrocephalus, unspecified	0.003	0.997	0.000
Q03.8 Other congenital hydrocephalus	0.003	0.997	0.000
Q03.1 Atresia of foramina of Magendie and Luschka	0.003	0.997	0.000
Q53.9 Undescended testicle, unspecified	0.003	0.997	0.000
Q53.0 Ectopic testis	0.003	0.997	0.000
Q35 Cleft palate	0.003	0.997	0.000
M24.85 Other specific joint derangements, not elsewhere classified (Pelvic region and thigh)	0.003	0.997	0.000
I60.6 Subarachnoid haemorrhage from other intracranial arteries	0.003	0.997	0.000
Q69.9 Polydactyly, unspecified	0.003	0.997	0.000
Q69.2 Accessory toe(s)	0.003	0.997	0.000
Q69.1 Accessory thumb(s)	0.003	0.997	0.000
Q69.0 Accessory finger(s)	0.003	0.997	0.000
Q70.9 Syndactyly, unspecified	0.003	0.997	0.000
Q70.4 Polysyndactyly	0.003	0.997	0.000
Q70.3 Webbed toes	0.003	0.997	0.000
Q70.2 Fused toes	0.003	0.997	0.000
Q70.1 Webbed fingers	0.003	0.997	0.000
Q70.0 Fused fingers	0.003	0.997	0.000
Q71.9 Reduction defect of upper limb, unspecified	0.003	0.997	0.000
Q71.8 Other reduction defects of upper limb(s)	0.003	0.997	0.000
Q71.6 Lobster-claw hand	0.003	0.997	0.000
Q71.5 Longitudinal reduction defect of ulna	0.003	0.997	0.000
Q71.4 Longitudinal reduction defect of radius	0.003	0.997	0.000
Q71.3 Congenital absence of hand and finger(s)	0.003	0.997	0.000
Q71.2 Congenital absence of both forearm and hand	0.003	0.997	0.000
Q71.1 Congenital absence of upper arm and forearm with hand present	0.003	0.997	0.000
Q71.0 Congenital complete absence of upper limb(s)	0.003	0.997	0.000
Q72.9 Reduction defect of lower limb, unspecified	0.003	0.997	0.000
Q72.8 Other reduction defects of lower limb(s)	0.003	0.997	0.000
Q72.7 Split foot	0.003	0.997	0.000
Q72.6 Longitudinal reduction defect of fibula	0.003	0.997	0.000
Q72.5 Longitudinal reduction defect of tibia	0.003	0.997	0.000
Q72.4 Longitudinal reduction defect of femur	0.003	0.997	0.000
Q72.3 Congenital absence of foot and toe(s)	0.003	0.997	0.000
Q72.2 Congenital absence of both lower leg and foot	0.003	0.997	0.000
Q72.1 Congenital absence of thigh and lower leg with foot present	0.003	0.997	0.000
Q72.0 Congenital complete absence of lower limb(s)	0.003	0.997	0.000
Q73.8 Other reduction defects of unspecified limb(s)	0.003	0.997	0.000
Q73.1 Phocomelia, unspecified limb(s)	0.003	0.997	0.000
Q73.0 Congenital absence of unspecified limb(s)	0.003	0.997	0.000
Q75.9 Congenital malformation of skull and face bones, unspecified	0.003	0.997	0.000
Q75.8 Other specified congenital malformations of skull and face bones	0.003	0.997	0.000
Q75.5 Oculomandibular dysostosis	0.003	0.997	0.000
Q75.4 Mandibulofacial dysostosis	0.003	0.997	0.000
Q75.3 Macrocephaly	0.003	0.997	0.000
Q75.2 Hypertelorism	0.003	0.997	0.000
Q75.1 Craniofacial dysostosis	0.003	0.997	0.000
Q75.0 Craniosynostosis	0.003	0.997	0.000
Q77.9 Osteochondrodysplasia with defects of growth of tubular bones and spine, unspecified	0.003	0.997	0.000
Q77.8 Other osteochondrodysplasia with defects of growth of tubular bones and spine	0.003	0.997	0.000
Q77.7 Spondyloepiphyseal dysplasia	0.003	0.997	0.000
Q77.6 Chondroectodermal dysplasia	0.003	0.997	0.000
Q77.5 Diastrophic dysplasia	0.003	0.997	0.000
Q77.4 Achondroplasia	0.003	0.997	0.000
Q77.3 Chondrodysplasia punctata	0.003	0.997	0.000
Q77.2 Short rib syndrome	0.003	0.997	0.000
Q77.1 Thanatophoric short stature	0.003	0.997	0.000
Q77.0 Achondrogenesis	0.003	0.997	0.000
I60.5 Subarachnoid haemorrhage from vertebral artery	0.003	0.997	0.000
Q34 Other congenital malformations of respiratory system	0.003	0.997	0.000
Q33 Congenital malformations of lung	0.003	0.997	0.000
Q32 Congenital malformations of trachea and bronchus	0.003	0.997	0.000
Q30 Congenital malformations of nose	0.003	0.997	0.000
Q53.1 Undescended testicle, unilateral	0.003	0.997	0.000
Q36 Cleft lip	0.003	0.997	0.000
Q11.1 Other anophthalmos	0.003	0.997	0.000
Q45.3 Other congenital malformations of pancreas and pancreatic duct	0.003	0.997	0.000
Q43 Other congenital malformations of intestine	0.003	0.997	0.000
Q86 Congenital malformation syndromes due to known exogenous causes, not elsewhere classified	0.003	0.997	0.000
Q84 Other congenital malformations of integument	0.003	0.997	0.000
Q81 Epidermolysis bullosa	0.003	0.997	0.000
Q80 Congenital ichthyosis	0.003	0.997	0.000
Q66.9 Congenital deformity of feet, unspecified	0.003	0.997	0.000
Q66.5 Congenital pes planus	0.003	0.997	0.000
Q66.4 Talipes calcaneovalgus	0.003	0.997	0.000
Q66.1 Talipes calcaneovarus	0.003	0.997	0.000
T86.1 Kidney transplant failure and rejection	0.003	0.997	0.000
Q90 Down's syndrome	0.003	0.997	0.000
M46.06 Spinal enthesopathy (Lumbar region)	0.003	0.997	0.000
Q40.8 Other specified congenital malformations of upper alimentary tract	0.003	0.997	0.000
Q79.9 Congenital malformation of musculoskeletal system, unspecified	0.003	0.997	0.000
Q79.5 Other congenital malformations of abdominal wall	0.003	0.997	0.000
Q79.4 Prune belly syndrome	0.003	0.997	0.000
Q79.3 Gastroschisis	0.003	0.997	0.000
Q79.2 Exomphalos	0.003	0.997	0.000
Q79.1 Other congenital malformations of diaphragm	0.003	0.997	0.000
Q79.0 Congenital diaphragmatic hernia	0.003	0.997	0.000
Q42 Congenital absence, atresia and stenosis of large intestine	0.003	0.997	0.000
Q41 Congenital absence, atresia and stenosis of small intestine	0.003	0.997	0.000
Q97 Other sex chromosome abnormalities, female phenotype, not elsewhere classified	0.003	0.997	0.000
Q95 Balanced rearrangements and structural markers, not elsewhere classified	0.003	0.997	0.000
Q93 Monosomies and deletions from the autosomes, not elsewhere classified	0.003	0.997	0.000
Q92 Other trisomies and partial trisomies of the autosomes, not elsewhere classified	0.003	0.997	0.000
Q91 Edwards' syndrome and Patau's syndrome	0.003	0.997	0.000
A48.4 Brazilian purpuric fever	0.003	0.997	0.000
A48.3 Toxic shock syndrome	0.003	0.997	0.000
A48.2 Nonpneumonic Legionnaires' disease [Pontiac fever]	0.003	0.997	0.000
A48.0 Gas gangrene	0.003	0.997	0.000
Q66.0 Talipes equinovarus	0.003	0.997	0.000
Q39 Congenital malformations of oesophagus	0.003	0.997	0.000
Q96 Turner's syndrome	0.003	0.997	0.000
Q78.9 Osteochondrodysplasia, unspecified	0.003	0.997	0.000
Q78.8 Other specified osteochondrodysplasias	0.003	0.997	0.000
Q78.6 Multiple congenital exostoses	0.003	0.997	0.000
Q78.5 Metaphyseal dysplasia	0.003	0.997	0.000
Q78.4 Enchondromatosis	0.003	0.997	0.000
Q78.3 Progressive diaphyseal dysplasia	0.003	0.997	0.000
Q78.2 Osteopetrosis	0.003	0.997	0.000
Q78.1 Polyostotic fibrous dysplasia	0.003	0.997	0.000
Q82.0 Hereditary lymphoedema	0.003	0.997	0.000
Q82.5 Congenital nonneoplastic naevus	0.003	0.997	0.000
Q03.0 Malformations of aqueduct of Sylvius	0.003	0.997	0.000
Q89 Other congenital malformations, not elsewhere classified	0.003	0.997	0.000
M48.56 Collapsed vertebra, not elsewhere classified (Lumbar region)	0.000	0.997	0.003
A40.1 Septicaemia due to streptococcus, group B	0.003	0.997	0.000
D62 Acute posthaemorrhagic anaemia	0.000	0.997	0.003
Q74.0 Other congenital malformations of upper limb(s), including shoulder girdle	0.003	0.997	0.000
Q83.9 Congenital malformation of breast, unspecified	0.003	0.997	0.000
Q83.3 Accessory nipple	0.003	0.997	0.000
Q83.2 Absent nipple	0.003	0.997	0.000
Q83.0 Congenital absence of breast with absent nipple	0.003	0.997	0.000
Z40 Prophylactic surgery	0.003	0.997	0.000
M46.26 Osteomyelitis of vertebra (Lumbar region)	0.003	0.997	0.000
A30-A49 Other bacterial diseases	0.003	0.997	0.000
Q11.3 Macrophthalmos	0.003	0.997	0.000
Q11.2 Microphthalmos	0.003	0.997	0.000
Q11.0 Cystic eyeball	0.003	0.997	0.000
Q56.4 Indeterminate sex, unspecified	0.003	0.997	0.000
Q56.3 Pseudohermaphroditism, unspecified	0.003	0.997	0.000
Q56.2 Female pseudohermaphroditism, not elsewhere classified	0.003	0.997	0.000
Q56.1 Male pseudohermaphroditism, not elsewhere classified	0.003	0.997	0.000
Q56.0 Hermaphroditism, not elsewhere classified	0.003	0.997	0.000
Q99.8 Other specified chromosome abnormalities	0.003	0.997	0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments	0.003	0.997	0.000
A49.1 Streptococcal infection, unspecified	0.003	0.997	0.000
Q40.1 Congenital hiatus hernia	0.003	0.997	0.000
Q43.3 Congenital malformations of intestinal fixation	0.003	0.997	0.000
Q51.8 Other congenital malformations of uterus and cervix	0.003	0.997	0.000
Q74.9 Unspecified congenital malformation of limb(s)	0.003	0.997	0.000
Q74.8 Other specified congenital malformations of limb(s)	0.003	0.997	0.000
Q74.3 Arthrogryposis multiplex congenita	0.003	0.997	0.000
M24.07 Loose body in joint (Ankle and foot)	0.003	0.997	0.000
Q55.2 Other congenital malformations of testis and scrotum	0.003	0.997	0.000
M46.19 Sacroiliitis, not elsewhere classified-Site unspe	0.003	0.997	0.000
Q40.2 Other specified congenital malformations of stomach	0.003	0.997	0.000
Q66.2 Metatarsus varus	0.003	0.997	0.000
K11 Diseases of salivary glands	0.000	0.997	0.003
Q44 Congenital malformations of gallbladder, bile ducts and liver	0.003	0.997	0.000
Q60 Renal agenesis and other reduction defects of kidney	0.003	0.997	0.000
M46.18 Sacroiliitis, not elsewhere classified-Sacral/sacrococ	0.003	0.997	0.000
A49.3 Mycoplasma infection, unspecified	0.003	0.997	0.000
Q31.0 Web of larynx	0.003	0.997	0.000
R79.9 Abnormal finding of blood chemistry, unspecified	0.003	0.997	0.000
Q98 Other sex chromosome abnormalities, male phenotype, not elsewhere classified	0.003	0.997	0.000
M46.09 Spinal enthesopathy (Site unspecified)	0.003	0.997	0.000
M46.08 Spinal enthesopathy (Sacral and sacrococcygeal region)	0.003	0.997	0.000
M46.07 Spinal enthesopathy (Lumbosacral region)	0.003	0.997	0.000
M46.05 Spinal enthesopathy (Thoracolumbar region)	0.003	0.997	0.000
M46.04 Spinal enthesopathy (Thoracic region)	0.003	0.997	0.000
M46.03 Spinal enthesopathy (Cervicothoracic region)	0.003	0.997	0.000
M46.02 Spinal enthesopathy (Cervical region)	0.003	0.997	0.000
M46.01 Spinal enthesopathy (Occipito-atlanto-axial region)	0.003	0.997	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations