TreeWAS – Variant ID: rs10905716

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E03.9 Hypothyroidism, unspecified	0.000	0.404	0.596
E03 Other hypothyroidism	0.000	0.532	0.468
E00-E07 Disorders of thyroid gland	0.000	0.615	0.385
E05 Thyrotoxicosis [hyperthyroidism]	0.000	0.631	0.369
E05.9 Thyrotoxicosis, unspecified	0.000	0.651	0.349
E04 Other non-toxic goitre	0.000	0.651	0.349
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.000	0.654	0.346
E04.2 Non-toxic multinodular goitre	0.000	0.660	0.340
E03.5 Myxoedema coma	0.000	0.664	0.336
E03.4 Atrophy of thyroid (acquired)	0.000	0.664	0.336
E03.3 Postinfectious hypothyroidism	0.000	0.664	0.336
E03.1 Congenital hypothyroidism without goitre	0.000	0.664	0.336
E03.0 Congenital hypothyroidism with diffuse goitre	0.000	0.664	0.336
E03.8 Other specified hypothyroidism	0.000	0.688	0.311
E05.8 Other thyrotoxicosis	0.000	0.708	0.292
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.708	0.292
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.724	0.276
E00 Congenital iodine-deficiency syndrome	0.000	0.724	0.276
E02 Subclinical iodine-deficiency hypothyroidism	0.000	0.729	0.271
E05.5 Thyroid crisis or storm	0.000	0.735	0.265
E05.4 Thyrotoxicosis factitia	0.000	0.735	0.265
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.000	0.735	0.265
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.000	0.735	0.265
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.000	0.742	0.258
E04.0 Non-toxic diffuse goitre	0.000	0.750	0.250
E04.8 Other specified non-toxic goitre	0.000	0.750	0.250
E04.1 Non-toxic single thyroid nodule	0.000	0.763	0.237
E06 Thyroiditis	0.000	0.783	0.217
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.000	0.802	0.198
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.000	0.802	0.198
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.000	0.802	0.198
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.000	0.802	0.198
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.802	0.198
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.000	0.802	0.198
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.000	0.802	0.198
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.000	0.802	0.198
E07 Other disorders of thyroid	0.000	0.824	0.175
E06.3 Autoimmune thyroiditis	0.000	0.837	0.163
E06.5 Other chronic thyroiditis	0.000	0.844	0.156
E06.4 Drug-induced thyroiditis	0.000	0.844	0.156
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.000	0.844	0.156
E06.0 Acute thyroiditis	0.000	0.844	0.156
E06.1 Subacute thyroiditis	0.000	0.864	0.136
E07.1 Dyshormogenetic goitre	0.000	0.874	0.126
E07.0 Hypersecretion of calcitonin	0.000	0.874	0.126
E04.9 Non-toxic goitre, unspecified	0.000	0.875	0.125
E06.9 Thyroiditis, unspecified	0.000	0.887	0.113
E07.8 Other specified disorders of thyroid	0.000	0.887	0.113
I49.9 Cardiac arrhythmia, unspecified	0.000	0.928	0.072
E07.9 Disorder of thyroid, unspecified	0.000	0.943	0.056
C79.8 Secondary malignant neoplasm of other specified sites	0.055	0.945	0.000
C79.6 Secondary malignant neoplasm of ovary	0.055	0.945	0.000
C79 Secondary malignant neoplasm of other sites	0.054	0.946	0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges	0.053	0.947	0.000
Z87.0 Personal history of diseases of the respiratory system	0.000	0.949	0.051
C79.7 Secondary malignant neoplasm of adrenal gland	0.048	0.952	0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis	0.043	0.957	0.000
A49.0 Staphylococcal infection, unspecified	0.000	0.957	0.043
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs	0.039	0.961	0.000
C79.2 Secondary malignant neoplasm of skin	0.036	0.963	0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system	0.033	0.967	0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow	0.032	0.968	0.000
M80.98 Unspecified osteoporosis with pathological fracture (Other)	0.031	0.969	0.000
B07 Viral warts	0.000	0.978	0.022
B37.0 Candidal stomatitis	0.015	0.985	0.000
C79.9 Secondary malignant neoplasm, unspecified site	0.014	0.985	0.000
M80.9 Unspecified osteoporosis with pathological fracture	0.015	0.985	0.000
M80.97 Unspecified osteoporosis with pathological fracture (Ankle and foot)	0.011	0.989	0.000
M80.96 Unspecified osteoporosis with pathological fracture (Lower leg)	0.011	0.989	0.000
M80.95 Unspecified osteoporosis with pathological fracture (Pelvic region and thigh)	0.011	0.989	0.000
M80.94 Unspecified osteoporosis with pathological fracture (Hand)	0.011	0.989	0.000
M80.93 Unspecified osteoporosis with pathological fracture (Forearm)	0.011	0.989	0.000
M80.92 Unspecified osteoporosis with pathological fracture (Upper arm)	0.011	0.989	0.000
M80.91 Unspecified osteoporosis with pathological fracture (Shoulder region)	0.011	0.989	0.000
I49 Other cardiac arrhythmias	0.000	0.989	0.011
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)	0.010	0.990	0.000
M80.99 Unspecified osteoporosis with pathological fracture (Site unspecified)	0.010	0.990	0.000
D63.8 Anaemia in other chronic diseases classified elsewhere	0.000	0.990	0.010
I49.3 Ventricular premature depolarisation	0.000	0.991	0.009
I49.1 Atrial premature depolarisation	0.000	0.992	0.008
I49.2 Junctional premature depolarisation	0.000	0.992	0.008
N10 Acute tubulo-interstitial nephritis	0.000	0.993	0.007
I49.4 Other and unspecified premature depolarisation	0.000	0.993	0.007
I49.8 Other specified cardiac arrhythmias	0.000	0.994	0.006
A49 Bacterial infection of unspecified site	0.000	0.994	0.006
Chapter IV Endocrine, nutritional and metabolic diseases	0.000	0.994	0.006
O69.1 Labour and delivery complicated by cord around neck, with compression	0.005	0.995	0.000
I49.0 Ventricular fibrillation and flutter	0.000	0.995	0.005
I49.5 Sick sinus syndrome	0.000	0.995	0.005
S62.30 Fracture of other metacarpal bone (closed)	0.000	0.995	0.005
E40-E46 Malnutrition	0.000	0.995	0.005
Z96.0 Presence of urogenital implants	0.000	0.995	0.005
J33.9 Nasal polyp, unspecified	0.000	0.995	0.005
B37 Candidiasis	0.005	0.995	0.000
E46 Unspecified protein-energy malnutrition	0.000	0.995	0.005
A49.3 Mycoplasma infection, unspecified	0.000	0.995	0.005
A49.2 Haemophilus influenzae infection, unspecified	0.000	0.995	0.005
A49.1 Streptococcal infection, unspecified	0.000	0.995	0.005
M80 Osteoporosis with pathological fracture	0.005	0.995	0.000
B37.8 Candidiasis of other sites	0.005	0.995	0.000
K75.0 Abscess of liver	0.000	0.996	0.004
B37.1 Pulmonary candidiasis	0.004	0.996	0.000
L98.0 Pyogenic granuloma	0.000	0.996	0.004
E44 Protein-energy malnutrition of moderate and mild degree	0.000	0.996	0.004
E45 Retarded development following protein-energy malnutrition	0.000	0.996	0.004
E43 Unspecified severe protein-energy malnutrition	0.000	0.996	0.004
E42 Marasmic kwashiorkor	0.000	0.996	0.004
E41 Nutritional marasmus	0.000	0.996	0.004
E40 Kwashiorkor	0.000	0.996	0.004
B37.6 Candidal endocarditis	0.004	0.996	0.000
B37.5 Candidal meningitis	0.004	0.996	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.000	0.996	0.004
Z91.6 Personal history of other physical trauma	0.000	0.996	0.004
Z35.1 Supervision of pregnancy with history of abortive outcome	0.004	0.996	0.000
K75 Other inflammatory liver diseases	0.000	0.996	0.004
M80.4 Drug-induced osteoporosis with pathological fracture	0.003	0.996	0.000
M80.3 Postsurgical malabsorption osteoporosis with pathological fracture	0.003	0.996	0.000
M80.2 Osteoporosis of disuse with pathological fracture	0.003	0.996	0.000
B37.2 Candidiasis of skin and nail	0.003	0.996	0.000
M80.5 Idiopathic osteoporosis with pathological fracture	0.003	0.996	0.000
M80.8 Other osteoporosis with pathological fracture	0.003	0.996	0.000
U80.1 Methicillin resistant agent	0.004	0.996	0.000
B37.4 Candidiasis of other urogenital sites	0.003	0.996	0.000
M80.0 Postmenopausal osteoporosis with pathological fracture	0.003	0.996	0.000
Z35.4 Supervision of pregnancy with grand multiparity	0.003	0.996	0.000
K75.4 Autoimmune hepatitis	0.000	0.996	0.003
K75.8 Other specified inflammatory liver diseases	0.000	0.997	0.003
Q61.3 Polycystic kidney, unspecified	0.000	0.997	0.003
N10-N16 Renal tubulo-interstitial diseases	0.000	0.997	0.003
L28.0 Lichen simplex chronicus	0.000	0.997	0.003
Q61.2 Polycystic kidney, adult type	0.000	0.997	0.003
Z35 Supervision of high-risk pregnancy	0.003	0.997	0.000
C18.9 Colon, unspecified	0.003	0.997	0.000
B37.7 Candidal septicaemia	0.003	0.997	0.000
E14.3 With ophthalmic complications	0.000	0.997	0.003
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.001	0.997	0.003
E44.1 Mild protein-energy malnutrition	0.000	0.997	0.003
E44.0 Moderate protein-energy malnutrition	0.000	0.997	0.003
A49.8 Other bacterial infections of unspecified site	0.000	0.997	0.003
Q61 Cystic kidney disease	0.000	0.997	0.003
B00.1 Herpesviral vesicular dermatitis	0.003	0.997	0.000
N11.9 Chronic tubulo-interstitial nephritis, unspecified	0.000	0.997	0.003
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee	0.003	0.997	0.000
N11 Chronic tubulo-interstitial nephritis	0.000	0.997	0.003
E65-E68 Obesity and other hyperalimentation	0.000	0.997	0.003
B37.3 Candidiasis of vulva and vagina	0.003	0.997	0.000
Z35.8 Supervision of other high-risk pregnancies	0.003	0.997	0.000
Z35.0 Supervision of pregnancy with history of infertility	0.003	0.997	0.000
I34.1 Mitral (valve) prolapse	0.000	0.997	0.003
E15 Nondiabetic hypoglycaemic coma	0.000	0.997	0.003
E10-E14 Diabetes mellitus	0.000	0.997	0.003
S62.3 Fracture of other metacarpal bone	0.000	0.997	0.003
K75.3 Granulomatous hepatitis, not elsewhere classified	0.000	0.997	0.003
K75.2 Nonspecific reactive hepatitis	0.000	0.997	0.003
K75.1 Phlebitis of portal vein	0.000	0.997	0.003
Q61.0 Congenital single renal cyst	0.000	0.997	0.003
M80.1 Postoophorectomy osteoporosis with pathological fracture	0.003	0.997	0.000
N15 Other renal tubulo-interstitial diseases	0.000	0.997	0.003
M80.29 Osteoporosis of disuse with pathological fracture (Site unspecified)	0.003	0.997	0.000
M80.28 Osteoporosis of disuse with pathological fracture (Other)	0.003	0.997	0.000
M80.27 Osteoporosis of disuse with pathological fracture (Ankle and foot)	0.003	0.997	0.000
M80.26 Osteoporosis of disuse with pathological fracture (Lower leg)	0.003	0.997	0.000
M80.25 Osteoporosis of disuse with pathological fracture (Pelvic region and thigh)	0.003	0.997	0.000
M80.24 Osteoporosis of disuse with pathological fracture (Hand)	0.003	0.997	0.000
M80.23 Osteoporosis of disuse with pathological fracture (Forearm)	0.003	0.997	0.000
M80.22 Osteoporosis of disuse with pathological fracture (Upper arm)	0.003	0.997	0.000
M80.21 Osteoporosis of disuse with pathological fracture (Shoulder region)	0.003	0.997	0.000
M80.20 Osteoporosis of disuse with pathological fracture (Multiple sites)	0.003	0.997	0.000
M80.39 Postsurgical malabsorption osteoporosis with pathological fracture (Site unspecified)	0.003	0.997	0.000
M80.38 Postsurgical malabsorption osteoporosis with pathological fracture (Other)	0.003	0.997	0.000
M80.37 Postsurgical malabsorption osteoporosis with pathological fracture (Ankle and foot)	0.003	0.997	0.000
M80.36 Postsurgical malabsorption osteoporosis with pathological fracture (Lower leg)	0.003	0.997	0.000
M80.35 Postsurgical malabsorption osteoporosis with pathological fracture (Pelvic region and thigh)	0.003	0.997	0.000
M80.34 Postsurgical malabsorption osteoporosis with pathological fracture (Hand)	0.003	0.997	0.000
M80.33 Postsurgical malabsorption osteoporosis with pathological fracture (Forearm)	0.003	0.997	0.000
M80.32 Postsurgical malabsorption osteoporosis with pathological fracture (Upper arm)	0.003	0.997	0.000
M80.31 Postsurgical malabsorption osteoporosis with pathological fracture (Shoulder region)	0.003	0.997	0.000
M80.30 Postsurgical malabsorption osteoporosis with pathological fracture (Multiple sites)	0.003	0.997	0.000
M80.49 Drug-induced osteoporosis with pathological fracture (Site unspecified)	0.003	0.997	0.000
M80.48 Drug-induced osteoporosis with pathological fracture (Other)	0.003	0.997	0.000
M80.47 Drug-induced osteoporosis with pathological fracture (Ankle and foot)	0.003	0.997	0.000
M80.46 Drug-induced osteoporosis with pathological fracture (Lower leg)	0.003	0.997	0.000
M80.45 Drug-induced osteoporosis with pathological fracture (Pelvic region and thigh)	0.003	0.997	0.000
M80.44 Drug-induced osteoporosis with pathological fracture (Hand)	0.003	0.997	0.000
M80.43 Drug-induced osteoporosis with pathological fracture (Forearm)	0.003	0.997	0.000
M80.42 Drug-induced osteoporosis with pathological fracture (Upper arm)	0.003	0.997	0.000
M80.41 Drug-induced osteoporosis with pathological fracture (Shoulder region)	0.003	0.997	0.000
M80.40 Drug-induced osteoporosis with pathological fracture (Multiple sites)	0.003	0.997	0.000
S20.8 Superficial injuries of other and unspecified parts of thorax	0.003	0.997	0.000
M80.59 Idiopathic osteoporosis with pathological fracture (Site unspecified)	0.003	0.997	0.000
M80.58 Idiopathic osteoporosis with pathological fracture (Other)	0.003	0.997	0.000
M80.57 Idiopathic osteoporosis with pathological fracture (Ankle and foot)	0.003	0.997	0.000
M80.56 Idiopathic osteoporosis with pathological fracture (Lower leg)	0.003	0.997	0.000
M80.55 Idiopathic osteoporosis with pathological fracture (Pelvic region and thigh)	0.003	0.997	0.000
M80.54 Idiopathic osteoporosis with pathological fracture (Hand)	0.003	0.997	0.000
M80.53 Idiopathic osteoporosis with pathological fracture (Forearm)	0.003	0.997	0.000
M80.51 Idiopathic osteoporosis with pathological fracture (Shoulder region)	0.003	0.997	0.000
M80.89 Other osteoporosis with pathological fracture (Site unspecified)	0.003	0.997	0.000
M80.87 Other osteoporosis with pathological fracture (Ankle and foot)	0.003	0.997	0.000
M80.86 Other osteoporosis with pathological fracture (Lower leg)	0.003	0.997	0.000
M80.85 Other osteoporosis with pathological fracture (Pelvic region and thigh)	0.003	0.997	0.000
M80.84 Other osteoporosis with pathological fracture (Hand)	0.003	0.997	0.000
M80.83 Other osteoporosis with pathological fracture (Forearm)	0.003	0.997	0.000
M80.82 Other osteoporosis with pathological fracture (Upper arm)	0.003	0.997	0.000
M80.81 Other osteoporosis with pathological fracture (Shoulder region)	0.003	0.997	0.000
M80.80 Other osteoporosis with pathological fracture (Multiple sites)	0.003	0.997	0.000
K75.9 Inflammatory liver disease, unspecified	0.000	0.997	0.003
M80.09 Postmenopausal osteoporosis with pathological fracture (Site unspecified)	0.003	0.997	0.000
M80.08 Postmenopausal osteoporosis with pathological fracture (Other)	0.003	0.997	0.000
M80.07 Postmenopausal osteoporosis with pathological fracture (Ankle and foot)	0.003	0.997	0.000
M80.06 Postmenopausal osteoporosis with pathological fracture (Lower leg)	0.003	0.997	0.000
M80.05 Postmenopausal osteoporosis with pathological fracture (Pelvic region and thigh)	0.003	0.997	0.000
M80.04 Postmenopausal osteoporosis with pathological fracture (Hand)	0.003	0.997	0.000
M80.03 Postmenopausal osteoporosis with pathological fracture (Forearm)	0.003	0.997	0.000
M80.02 Postmenopausal osteoporosis with pathological fracture (Upper arm)	0.003	0.997	0.000
M80.01 Postmenopausal osteoporosis with pathological fracture (Shoulder region)	0.003	0.997	0.000
M80.52 Idiopathic osteoporosis with pathological fracture (Upper arm)	0.003	0.997	0.000
M80.50 Idiopathic osteoporosis with pathological fracture (Multiple sites)	0.003	0.997	0.000
Z35.5 Supervision of elderly primigravida	0.003	0.997	0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic	0.000	0.997	0.003
M80.88 Other osteoporosis with pathological fracture (Other)	0.003	0.997	0.000
B08 Other viral infections characterised by skin and mucous membrane lesions, not elsewhere classified	0.000	0.997	0.002
E14 Unspecified diabetes mellitus	0.000	0.997	0.003
M92.6 Juvenile osteochondrosis of tarsus	0.003	0.997	0.000
Z82.3 Family history of stroke	0.003	0.997	0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere	0.000	0.997	0.003
I08.1 Disorders of both mitral and tricuspid valves	0.000	0.997	0.003
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions	0.000	0.997	0.003
M80.00 Postmenopausal osteoporosis with pathological fracture (Multiple sites)	0.003	0.997	0.000
Z35.7 Supervision of high-risk pregnancy due to social problems	0.003	0.997	0.000
Z35.6 Supervision of very young primigravida	0.003	0.997	0.000
Z35.3 Supervision of pregnancy with history of insufficient antenatal care	0.003	0.997	0.000
D63 Anaemia in chronic diseases classified elsewhere	0.000	0.997	0.003
Q61.5 Medullary cystic kidney	0.000	0.997	0.003
A49.9 Bacterial infection, unspecified	0.001	0.997	0.002
T90.4 Sequelae of injury of eye and orbit	0.003	0.997	0.000
B00 Herpesviral [herpes simplex] infections	0.002	0.997	0.001
E10.9 Without complications	0.000	0.997	0.003
U80.8 Agent resistant to other penicillin-related antibiotic	0.003	0.997	0.000
B06 Rubella [German measles]	0.001	0.997	0.002
B05 Measles	0.001	0.997	0.002
B09 Unspecified viral infection characterised by skin and mucous membrane lesions	0.001	0.997	0.002
B04 Monkeypox	0.001	0.997	0.002
B03 Smallpox	0.001	0.997	0.002
S83.2 Tear of meniscus, current	0.003	0.997	0.000
E50-E64 Other nutritional deficiencies	0.000	0.997	0.003
S62.31 Fracture of other metacarpal bone (open)	0.000	0.997	0.002
Q61.8 Other cystic kidney diseases	0.000	0.997	0.002
Q61.1 Polycystic kidney, infantile type	0.000	0.997	0.002
U80 Agent resistant to penicillin and related antibiotics	0.003	0.997	0.000
Q61.9 Cystic kidney disease, unspecified	0.000	0.997	0.002
F81.9 Developmental disorder of scholastic skills, unspecified	0.000	0.997	0.002
Z35.9 Supervision of high-risk pregnancy, unspecified	0.002	0.997	0.000
E67 Other hyperalimentation	0.000	0.998	0.002
E68 Sequelae of hyperalimentation	0.000	0.998	0.002
N11.8 Other chronic tubulo-interstitial nephritis	0.000	0.998	0.002
N11.0 Nonobstructive reflux-associated chronic pyelonephritis	0.000	0.998	0.002
N15.1 Renal and perinephric abscess	0.000	0.998	0.002
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.002	0.998	0.000
N15.9 Renal tubulo-interstitial disease, unspecified	0.000	0.998	0.002
B08.1 Molluscum contagiosum	0.000	0.998	0.002
E65 Localised adiposity	0.000	0.998	0.002
Q61.4 Renal dysplasia	0.000	0.998	0.002
E12 Malnutrition-related diabetes mellitus	0.000	0.998	0.002
T90.2 Sequelae of fracture of skull and facial bones	0.002	0.998	0.000
M80.19 Postoophorectomy osteoporosis with pathological fracture (Site unspecified)	0.002	0.998	0.000
M80.18 Postoophorectomy osteoporosis with pathological fracture (Other)	0.002	0.998	0.000
M80.17 Postoophorectomy osteoporosis with pathological fracture (Ankle and foot)	0.002	0.998	0.000
M80.16 Postoophorectomy osteoporosis with pathological fracture (Lower leg)	0.002	0.998	0.000
M80.15 Postoophorectomy osteoporosis with pathological fracture (Pelvic region and thigh)	0.002	0.998	0.000
M80.14 Postoophorectomy osteoporosis with pathological fracture (Hand)	0.002	0.998	0.000
M80.13 Postoophorectomy osteoporosis with pathological fracture (Forearm)	0.002	0.998	0.000
M80.12 Postoophorectomy osteoporosis with pathological fracture (Upper arm)	0.002	0.998	0.000
M80.11 Postoophorectomy osteoporosis with pathological fracture (Shoulder region)	0.002	0.998	0.000
N15.8 Other specified renal tubulo-interstitial diseases	0.000	0.998	0.002
N15.0 Balkan nephropathy	0.000	0.998	0.002
E10 Insulin-dependent diabetes mellitus	0.000	0.998	0.002
E14.9 Without complications	0.000	0.998	0.002
H21.0 Hyphaema	0.002	0.998	0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.000	0.998	0.002
T92.0 Sequelae of open wound of upper limb	0.002	0.998	0.000
E14.4 With neurological complications	0.000	0.998	0.002
S83.7 Injury to multiple structures of knee	0.002	0.998	0.000
I34.2 Nonrheumatic mitral (valve) stenosis	0.000	0.998	0.002
M22.8 Other disorders of patella	0.000	0.998	0.002
B01 Varicella [chickenpox]	0.001	0.998	0.002
Z35.2 Supervision of pregnancy with other poor reproductive or obstetric history	0.002	0.998	0.000
B00.5 Herpesviral ocular disease	0.002	0.998	0.001
B08.8 Other specified viral infections characterised by skin and mucous membrane lesions	0.000	0.998	0.002
B08.5 Enteroviral vesicular pharyngitis	0.000	0.998	0.002
B08.4 Enteroviral vesicular stomatitis with exanthem	0.000	0.998	0.002
B08.3 Erythema infectiosum [fifth disease]	0.000	0.998	0.002
B08.2 Exanthema subitum [sixth disease]	0.000	0.998	0.002
B08.0 Other orthopoxvirus infections	0.000	0.998	0.002
T90.5 Sequelae of intracranial injury	0.002	0.998	0.000
E16 Other disorders of pancreatic internal secretion	0.000	0.998	0.002
E14.7 With multiple complications	0.000	0.998	0.002
E14.5 With peripheral circulatory complications	0.000	0.998	0.002
N16.8 Renal tubulo-interstitial disorders in other diseases classified elsewhere	0.000	0.998	0.002
N16.5 Renal tubulo-interstitial disorders in transplant rejection	0.000	0.998	0.002
N16.4 Renal tubulo-interstitial disorders in systemic connective tissue disorders	0.000	0.998	0.002
N16.3 Renal tubulo-interstitial disorders in metabolic diseases	0.000	0.998	0.002
N16.2 Renal tubulo-interstitial disorders in blood diseases and disorders involving the immune mechanism	0.000	0.998	0.002
N16.1 Renal tubulo-interstitial disorders in neoplastic diseases	0.000	0.998	0.002
N16.0 Renal tubulo-interstitial disorders in infectious and parasitic diseases classified elsewhere	0.000	0.998	0.002
O69 Labour and delivery complicated by umbilical cord complications	0.002	0.998	0.000
E14.8 With unspecified complications	0.000	0.998	0.002
L05.9 Pilonidal cyst without abscess	0.000	0.998	0.002
N14.4 Toxic nephropathy, not elsewhere classified	0.000	0.998	0.002
N14.3 Nephropathy induced by heavy metals	0.000	0.998	0.002
N14.2 Nephropathy induced by unspecified drug, medicament or biological substance	0.000	0.998	0.002
N14.0 Analgesic nephropathy	0.000	0.998	0.002
S83.4 Sprain and strain involving (fibular)(tibial) collateral ligamnent of knee	0.002	0.998	0.000
D63.1 Anaemia in other chronic diseases classified elsewhere	0.000	0.998	0.002
B00.8 Other forms of herpesviral infection	0.001	0.998	0.001
B00.7 Disseminated herpesviral disease	0.001	0.998	0.001
B00.3 Herpesviral meningitis	0.001	0.998	0.001
B00.0 Eczema herpeticum	0.001	0.998	0.001
T90 Sequelae of injuries of head	0.002	0.998	0.000
N14.1 Nephropathy induced by other drugs, medicaments and biological substances	0.000	0.998	0.002
B05.9 Measles without complication	0.001	0.998	0.002
B05.8 Measles with other complications	0.001	0.998	0.002
B05.4 Measles with intestinal complications	0.001	0.998	0.002
B05.3 Measles complicated by otitis media	0.001	0.998	0.002
B05.2 Measles complicated by pneumonia	0.001	0.998	0.002
B05.1 Measles complicated by meningitis	0.001	0.998	0.002
B05.0 Measles complicated by encephalitis	0.001	0.998	0.002
B06.9 Rubella without complication	0.001	0.998	0.002
B06.8 Rubella with other complications	0.001	0.998	0.002
B06.0 Rubella with neurological complications	0.001	0.998	0.002
I34 Nonrheumatic mitral valve disorders	0.000	0.998	0.002
S72.00 Fracture of neck of femur (closed)	0.002	0.998	0.000
N11.1 Chronic obstructive pyelonephritis	0.000	0.998	0.002
T90.1 Sequelae of open wound of head	0.002	0.998	0.000
E64 Sequelae of malnutrition and other nutritional deficiencies	0.000	0.998	0.002
E63 Other nutritional deficiencies	0.000	0.998	0.002
E56 Other vitamin deficiencies	0.000	0.998	0.002
E51 Thiamine deficiency	0.000	0.998	0.002
E50 Vitamin A deficiency	0.000	0.998	0.002
E60 Dietary zinc deficiency	0.000	0.998	0.002
E59 Dietary selenium deficiency	0.000	0.998	0.002
E58 Dietary calcium deficiency	0.000	0.998	0.002
E54 Ascorbic acid deficiency	0.000	0.998	0.002
E52 Niacin deficiency [pellagra]	0.000	0.998	0.002
B00.2 Herpesviral gingivostomatitis and pharyngotonsillitis	0.001	0.998	0.001
E16.0 Drug-induced hypoglycaemia without coma	0.000	0.998	0.002
Z82.0 Family history of epilepsy and other diseases of the nervous system	0.002	0.998	0.000
B00.4 Herpesviral encephalitis	0.001	0.998	0.001
E67.8 Other specified hyperalimentation	0.000	0.998	0.002
E67.3 Hypervitaminosis D	0.000	0.998	0.002
E67.2 Megavitamin-B6 syndrome	0.000	0.998	0.002
E67.1 Hypercarotenaemia	0.000	0.998	0.002
E67.0 Hypervitaminosis A	0.000	0.998	0.002
S83.3 Tear of articular cartilage of knee, current	0.002	0.998	0.000
S83.1 Dislocation of knee	0.002	0.998	0.000
S83.0 Dislocation of patella	0.002	0.998	0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified	0.000	0.998	0.002
E14.2 Withrenal complications	0.000	0.998	0.002
B37.9 Candidiasis, unspecified	0.002	0.998	0.000
E12.9 Without complications	0.000	0.998	0.002
E12.8 With unspecified complications	0.000	0.998	0.002
E12.7 With multiple complications	0.000	0.998	0.002
E12.6 With other specified complications	0.000	0.998	0.002
E12.5 With peripheral circulatory complications	0.000	0.998	0.002
E12.4 With neurological complications	0.000	0.998	0.002
E12.3 With ophthalmic complications	0.000	0.998	0.002
E12.2 With renal complications	0.000	0.998	0.002
E12.1 With ketoacidosis	0.000	0.998	0.002
E12.0 With coma	0.000	0.998	0.002
E14.0 With coma	0.000	0.998	0.002
N13.4 Hydroureter	0.000	0.998	0.002
E10.4 With neurological complications	0.000	0.998	0.002
G63.2 Diabetic polyneuropathy	0.000	0.998	0.002
E10.7 With multiple complications	0.000	0.998	0.002
E14.6 With other specified complications	0.000	0.998	0.002
N13.5 Kinking and stricture of ureter without hydronephrosis	0.000	0.998	0.002
B00.9 Herpesviral infection, unspecified	0.001	0.998	0.001
E10.3 With ophthalmic complications	0.000	0.998	0.002
E14.1 With ketoacidosis	0.000	0.998	0.002
E61 Deficiency of other nutrient elements	0.000	0.998	0.002
B01.2 Varicella pneumonia	0.001	0.998	0.001
B01.1 Varicella encephalitis	0.001	0.998	0.001
B01.0 Varicella meningitis	0.001	0.998	0.001
O69.0 Labour and delivery complicated by prolapse of cord	0.002	0.998	0.000
Y88.3 Sequelae of surgical and medical procedures as the cause of abnormal reaction of the patient or of later complication, without mention of misadventure at the time of the procedure	0.000	0.998	0.002
N60.1 Diffuse cystic mastopathy	0.002	0.998	0.000
L28 Lichen simplex chronicus and prurigo	0.000	0.998	0.002
E16.9 Disorder of pancreatic internal secretion, unspecified	0.000	0.998	0.002
E16.8 Other specified disorders of pancreatic internal secretion	0.000	0.998	0.002
E16.4 Abnormal secretion of gastrin	0.000	0.998	0.002
E16.3 Increased secretion of glucagon	0.000	0.998	0.002
N95.8 Other specified menopausal and perimenopausal disorders	0.002	0.998	0.000
O69.5 Labour and delivery complicated by vascular lesion of cord	0.002	0.998	0.000
O69.4 Labour and delivery complicated by vasa praevia	0.002	0.998	0.000
O69.3 Labour and delivery complicated by short cord	0.002	0.998	0.000
R09.3 Abnormal sputum	0.000	0.998	0.002
S83.6 Sprain and strain of other and unspecified parts of knee	0.002	0.998	0.000
E13 Other specified diabetes mellitus	0.000	0.998	0.002
E10.6 With other specified complications	0.000	0.998	0.002
E10.5 With peripheral circulatory complications	0.000	0.998	0.002
O69.8 Labour and delivery complicated by other cord complications	0.002	0.998	0.000
B01.8 Varicella with other complications	0.001	0.998	0.001
T90.3 Sequelae of injury of cranial nerves	0.002	0.998	0.000
T90.0 Sequelae of superficial injury of head	0.002	0.998	0.000
S62.50 Fracture of thumb (closed)	0.000	0.998	0.002
O69.2 Labour and delivery complicated by other cord entanglement	0.002	0.998	0.000
B01.9 Varicella without complications	0.001	0.998	0.001
E10.8 With unspecified complications	0.000	0.998	0.002
E10.0 With coma	0.000	0.998	0.002
E50.9 Vitamin A deficiency, unspecified	0.000	0.998	0.002
E50.8 Other manifestations of vitamin A deficiency	0.000	0.998	0.002
E50.7 Other ocular manifestations of vitamin A deficiency	0.000	0.998	0.002
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.000	0.998	0.002
E50.5 Vitamin A deficiency with night blindness	0.000	0.998	0.002
E50.4 Vitamin A deficiency with keratomalacia	0.000	0.998	0.002
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.000	0.998	0.002
E50.2 Vitamin A deficiency with corneal xerosis	0.000	0.998	0.002
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.000	0.998	0.002
E50.0 Vitamin A deficiency with conjunctival xerosis	0.000	0.998	0.002
E51.9 Thiamine deficiency, unspecified	0.000	0.998	0.002
E51.8 Other manifestations of thiamine deficiency	0.000	0.998	0.002
E51.2 Wernicke's encephalopathy	0.000	0.998	0.002
E51.1 Beriberi	0.000	0.998	0.002
E56.9 Vitamin deficiency, unspecified	0.000	0.998	0.002
E56.8 Deficiency of other vitamins	0.000	0.998	0.002
E56.1 Deficiency of vitamin K	0.000	0.998	0.002
E56.0 Deficiency of vitamin E	0.000	0.998	0.002
E63.9 Nutritional deficiency, unspecified	0.000	0.998	0.002
E63.8 Other specified nutritional deficiencies	0.000	0.998	0.002
E63.1 Imbalance of constituents of food intake	0.000	0.998	0.002
E63.0 Essential fatty acid [EFA] deficiency	0.000	0.998	0.002
E64.9 Sequelae of unspecified nutritional deficiency	0.000	0.998	0.002
E64.8 Sequelae of other nutritional deficiencies	0.000	0.998	0.002
E64.3 Sequelae of rickets	0.000	0.998	0.002
E64.2 Sequelae of vitamin C deficiency	0.000	0.998	0.002
E64.1 Sequelae of vitamin A deficiency	0.000	0.998	0.002
E64.0 Sequelae of protein-energy malnutrition	0.000	0.998	0.002
E88.2 Lipomatosis, not elsewhere classified	0.002	0.998	0.000
E10.2 With renal complications	0.000	0.998	0.002
H21.9 Disorder of iris and ciliary body, unspecified	0.002	0.998	0.000
H21.1 Other vascular disorders of iris and ciliary body	0.002	0.998	0.000
N13 Obstructive and reflux uropathy	0.000	0.998	0.002
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.002	0.998	0.000
L28.1 Prurigo nodularis	0.000	0.998	0.002
T90.8 Sequelae of other specified injuries of head	0.002	0.998	0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified	0.002	0.998	0.000
I34.8 Other nonrheumatic mitral valve disorders	0.000	0.998	0.002
N13.0 Hydronephrosis with ureteropelvic junction obstruction	0.000	0.998	0.002
U80.0 Penicillin resistant agent	0.002	0.998	0.000
Z82.5 Family history of asthma and other chronic lower respiratory diseases	0.002	0.998	0.000
E61.9 Deficiency of nutrient element, unspecified	0.000	0.998	0.001
E61.8 Deficiency of other specified nutrient elements	0.000	0.998	0.001
E61.7 Deficiency of multiple nutrient elements	0.000	0.998	0.001
E61.6 Vanadium deficiency	0.000	0.998	0.001
E61.5 Molybdenum deficiency	0.000	0.998	0.001
E61.4 Chromium deficiency	0.000	0.998	0.001
E61.3 Manganese deficiency	0.000	0.998	0.001
E61.0 Copper deficiency	0.000	0.998	0.001
G62.8 Other specified polyneuropathies	0.000	0.998	0.002
H21 Other disorders of iris and ciliary body	0.002	0.998	0.000
M80.10 Postoophorectomy osteoporosis with pathological fracture (Multiple sites)	0.001	0.998	0.001
L28.2 Other prurigo	0.000	0.998	0.001
B02 Zoster [herpes zoster]	0.001	0.998	0.001
E13.8 With unspecified complications	0.000	0.998	0.001
E13.7 With multiple complications	0.000	0.998	0.001
E13.6 With other specified complications	0.000	0.998	0.001
E13.5 With peripheral circulatory complications	0.000	0.998	0.001
E13.4 With neurological complications	0.000	0.998	0.001
E13.3 With ophthalmic complications	0.000	0.998	0.001
E13.2 With renal complications	0.000	0.998	0.001
E13.1 With ketoacidosis	0.000	0.998	0.001
E13.0 With coma	0.000	0.998	0.001
E27.4 Other and unspecified adrenocortical insufficiency	0.000	0.998	0.002
I08.0 Disorders of both mitral and aortic valves	0.000	0.998	0.002
E55 Vitamin D deficiency	0.000	0.998	0.002
J81 Pulmonary oedema	0.000	0.998	0.002
E16.1 Other hypoglycaemia	0.000	0.998	0.001
E61.2 Magnesium deficiency	0.000	0.998	0.001
G62.0 Drug-induced polyneuropathy	0.000	0.998	0.002
I34.0 Mitral (valve) insufficiency	0.000	0.998	0.002
N64.8 Other specified disorders of breast	0.002	0.998	0.000
Z87.3 Personal history of diseases of the musculoskeletal system and connective tissue	0.000	0.998	0.002
J33 Nasal polyp	0.000	0.998	0.002
K74.6 Other and unspecified cirrhosis of liver	0.000	0.998	0.002
Q63.1 Lobulated, fused and horseshoe kidney	0.001	0.998	0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement	0.002	0.998	0.000
K73.2 Chronic active hepatitis, not elsewhere classified	0.000	0.998	0.001
O69.9 Labour and delivery complicated by cord complication, unspecified	0.001	0.998	0.000
Z87 Personal history of other diseases and conditions	0.000	0.998	0.002
E61.1 Iron deficiency	0.000	0.998	0.001
J94.8 Other specified pleural conditions	0.000	0.998	0.001
K74.5 Biliary cirrhosis, unspecified	0.000	0.998	0.001
T92.1 Sequelae of fracture of arm	0.001	0.998	0.000
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified	0.000	0.998	0.001
K74 Fibrosis and cirrhosis of liver	0.000	0.998	0.002
B02.3 Zoster ocular disease	0.001	0.999	0.000
D22.1 Melanocytic naevi of eyelid, including canthus	0.000	0.999	0.001
E10.1 With ketoacidosis	0.000	0.999	0.001
H21.4 Pupillary membranes	0.001	0.999	0.000
H21.3 Cyst of iris, ciliary body and anterior chamber	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations