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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs10965243
log Bayes Factor = 6.81858
Chromosome 9   position 22,130,065  (GRCh37) Explore rs10965243 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E11.9 Without complications
0.000 0.000 1.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.004 0.996
E11.3 With ophthalmic complications
0.000 0.022 0.978
E10-E14 Diabetes mellitus
0.000 0.124 0.876
E11.6 With other specified complications
0.000 0.131 0.869
E14 Unspecified diabetes mellitus
0.000 0.134 0.866
E11.4 With neurological complications
0.000 0.156 0.844
E14.3 With ophthalmic complications
0.000 0.176 0.824
E14.9 Without complications
0.000 0.177 0.823
E11.0 With coma
0.000 0.221 0.779
E11.7 With multiple complications
0.000 0.286 0.714
E11.5 With peripheral circulatory complications
0.000 0.300 0.700
E11.1 With ketoacidosis
0.000 0.316 0.684
E11.8 With unspecified complications
0.000 0.325 0.675
E12 Malnutrition-related diabetes mellitus
0.000 0.372 0.628
E14.8 With unspecified complications
0.000 0.379 0.621
E14.7 With multiple complications
0.000 0.379 0.621
E14.6 With other specified complications
0.000 0.379 0.621
E14.5 With peripheral circulatory complications
0.000 0.379 0.621
E14.4 With neurological complications
0.000 0.379 0.621
E14.2 Withrenal complications
0.000 0.379 0.621
E14.1 With ketoacidosis
0.000 0.379 0.621
E14.0 With coma
0.000 0.379 0.621
E11.2 With renal complications
0.000 0.474 0.526
I50.0 Congestive heart failure
0.000 0.480 0.520
E13 Other specified diabetes mellitus
0.000 0.490 0.510
I50 Heart failure
0.000 0.492 0.508
I30-I52 Other forms of heart disease
0.000 0.504 0.496
I51 Complications and ill-defined descriptions of heart disease
0.000 0.507 0.493
I49 Other cardiac arrhythmias
0.000 0.509 0.491
I49.3 Ventricular premature depolarisation
0.000 0.517 0.483
I49.8 Other specified cardiac arrhythmias
0.000 0.519 0.481
I51.8 Other ill-defined heart diseases
0.000 0.526 0.474
I50.9 Heart failure, unspecified
0.000 0.548 0.452
E12.9 Without complications
0.000 0.549 0.450
E12.8 With unspecified complications
0.000 0.549 0.450
E12.7 With multiple complications
0.000 0.549 0.450
E12.6 With other specified complications
0.000 0.549 0.450
E12.5 With peripheral circulatory complications
0.000 0.549 0.450
E12.4 With neurological complications
0.000 0.549 0.450
E12.3 With ophthalmic complications
0.000 0.549 0.450
E12.2 With renal complications
0.000 0.549 0.450
E12.1 With ketoacidosis
0.000 0.549 0.450
E12.0 With coma
0.000 0.549 0.450
I51.7 Cardiomegaly
0.000 0.552 0.448
I42 Cardiomyopathy
0.000 0.566 0.434
I36 Nonrheumatic tricuspid valve disorders
0.000 0.584 0.416
I51.6 Cardiovascular disease, unspecified
0.000 0.604 0.396
E10 Insulin-dependent diabetes mellitus
0.000 0.612 0.388
I51.3 Intracardiac thrombosis, not elsewhere classified
0.000 0.614 0.386
I45 Other conduction disorders
0.000 0.623 0.377
I42.1 Obstructive hypertrophic cardiomyopathy
0.000 0.627 0.373
I51.0 Cardiac septal defect, acquired
0.000 0.632 0.368
I49.0 Ventricular fibrillation and flutter
0.000 0.634 0.366
E13.8 With unspecified complications
0.000 0.634 0.366
E13.7 With multiple complications
0.000 0.634 0.366
E13.6 With other specified complications
0.000 0.634 0.366
E13.5 With peripheral circulatory complications
0.000 0.634 0.366
E13.4 With neurological complications
0.000 0.634 0.366
E13.3 With ophthalmic complications
0.000 0.634 0.366
E13.2 With renal complications
0.000 0.634 0.366
E13.1 With ketoacidosis
0.000 0.634 0.366
E13.0 With coma
0.000 0.634 0.366
I36.1 Nonrheumatic tricuspid (valve) insufficiency
0.000 0.642 0.358
I52 Other heart disorders in diseases classified elsewhere
0.000 0.644 0.356
I48 Atrial fibrillation and flutter
0.000 0.644 0.356
I43 Cardiomyopathy in diseases classified elsewhere
0.000 0.644 0.356
I41 Myocarditis in diseases classified elsewhere
0.000 0.644 0.356
I40 Acute myocarditis
0.000 0.644 0.356
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.000 0.644 0.356
I32 Pericarditis in diseases classified elsewhere
0.000 0.644 0.356
I51.5 Myocardial degeneration
0.000 0.647 0.353
I51.2 Rupture of papillary muscle, not elsewhere classified
0.000 0.647 0.353
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.000 0.648 0.352
I49.2 Junctional premature depolarisation
0.000 0.648 0.352
I51.4 Myocarditis, unspecified
0.000 0.653 0.347
I42.6 Alcoholic cardiomyopathy
0.000 0.653 0.347
I42.0 Dilated cardiomyopathy
0.000 0.655 0.345
I47 Paroxysmal tachycardia
0.000 0.656 0.344
I49.4 Other and unspecified premature depolarisation
0.000 0.661 0.339
I33 Acute and subacute endocarditis
0.000 0.663 0.337
I38 Endocarditis, valve unspecified
0.000 0.667 0.333
I37 Pulmonary valve disorders
0.000 0.682 0.318
I42.7 Cardiomyopathy due to drugs and other external agents
0.000 0.689 0.311
I42.5 Other restrictive cardiomyopathy
0.000 0.689 0.311
I42.4 Endocardial fibroelastosis
0.000 0.689 0.311
I42.3 Endomyocardial (eosinophilic) disease
0.000 0.689 0.311
I30 Acute pericarditis
0.000 0.696 0.304
I42.9 Cardiomyopathy, unspecified
0.000 0.696 0.304
I42.2 Other hypertrophic cardiomyopathy
0.000 0.697 0.303
I45.6 Preexcitation syndrome
0.000 0.701 0.298
I36.9 Nonrheumatic tricuspid valve disorder, unspecified
0.000 0.702 0.298
I36.8 Other nonrheumatic tricuspid valve disorders
0.000 0.702 0.298
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency
0.000 0.702 0.298
I36.0 Nonrheumatic tricuspid (valve) stenosis
0.000 0.702 0.298
I51.9 Heart disease, unspecified
0.000 0.702 0.298
I45.2 Bifascicular block
0.000 0.702 0.297
I45.3 Trifascicular block
0.000 0.710 0.290
E10.8 With unspecified complications
0.000 0.712 0.288
E10.1 With ketoacidosis
0.000 0.712 0.288
I42.8 Other cardiomyopathies
0.000 0.717 0.282
E10.2 With renal complications
0.000 0.720 0.280
E10.7 With multiple complications
0.000 0.721 0.278
E10.0 With coma
0.000 0.721 0.278
I47.1 Supraventricular tachycardia
0.000 0.722 0.278
E10.4 With neurological complications
0.000 0.723 0.277
I60-I69 Cerebrovascular diseases
0.000 0.723 0.277
I31 Other diseases of pericardium
0.000 0.725 0.275
Chapter IX Diseases of the circulatory system
0.000 0.726 0.274
I47.9 Paroxysmal tachycardia, unspecified
0.000 0.726 0.274
I45.8 Other specified conduction disorders
0.000 0.728 0.272
I45.4 Nonspecific intraventricular block
0.000 0.730 0.270
I45.0 Right fascicular block
0.000 0.730 0.270
I45.1 Other and unspecified right bundle-branch block
0.000 0.730 0.270
I61 Intracerebral haemorrhage
0.000 0.732 0.268
I49.5 Sick sinus syndrome
0.000 0.738 0.262
E10.5 With peripheral circulatory complications
0.000 0.740 0.260
I67 Other cerebrovascular diseases
0.000 0.742 0.258
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.000 0.742 0.257
I61.9 Intracerebral haemorrhage, unspecified
0.000 0.743 0.257
I32.8 Pericarditis in other diseases classified elsewhere
0.000 0.745 0.255
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere
0.000 0.745 0.255
I32.0 Pericarditis in bacterial diseases classified elsewhere
0.000 0.745 0.255
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere
0.000 0.745 0.255
I39.4 Multiple valve disorders in diseases classified elsewhere
0.000 0.745 0.255
I39.3 Pulmonary valve disorders in diseases classified elsewhere
0.000 0.745 0.255
I39.2 Tricuspid valve disorders in diseases classified elsewhere
0.000 0.745 0.255
I39.1 Aortic valve disorders in diseases classified elsewhere
0.000 0.745 0.255
I39.0 Mitral valve disorders in diseases classified elsewhere
0.000 0.745 0.255
I40.9 Acute myocarditis, unspecified
0.000 0.745 0.255
I40.8 Other acute myocarditis
0.000 0.745 0.255
I40.1 Isolated myocarditis
0.000 0.745 0.255
I40.0 Infective myocarditis
0.000 0.745 0.255
I41.8 Myocarditis in other diseases classified elsewhere
0.000 0.745 0.255
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere
0.000 0.745 0.255
I41.1 Myocarditis in viral diseases classified elsewhere
0.000 0.745 0.255
I41.0 Myocarditis in bacterial diseases classified elsewhere
0.000 0.745 0.255
I43.8 Cardiomyopathy in other diseases classified elsewhere
0.000 0.745 0.255
I43.2 Cardiomyopathy in nutritional diseases
0.000 0.745 0.255
I43.1 Cardiomyopathy in metabolic diseases
0.000 0.745 0.255
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere
0.000 0.745 0.255
I48.9 Atrial fibrillation and atrial flutter, unspecified
0.000 0.745 0.255
I48.4 Atypical atrial flutter
0.000 0.745 0.255
I48.3 Typical atrial flutter
0.000 0.745 0.255
I48.2 Chronic atrial fibrillation
0.000 0.745 0.255
I48.1 Persistent atrial fibrillation
0.000 0.745 0.255
I48.0 Paroxysmal atrial fibrillation
0.000 0.745 0.255
I52.8 Other heart disorders in other diseases classified elsewhere
0.000 0.745 0.255
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.745 0.255
I52.0 Other heart disorders in bacterial diseases classified elsewhere
0.000 0.745 0.255
E10.6 With other specified complications
0.000 0.745 0.255
I47.0 Reentry ventricular arrhythmia
0.000 0.750 0.250
E13.9 Without complications
0.001 0.752 0.247
I67.9 Cerebrovascular disease, unspecified
0.000 0.753 0.247
I46 Cardiac arrest
0.000 0.753 0.247
I45.5 Other specified heart block
0.000 0.755 0.245
I65.2 Occlusion and stenosis of carotid artery
0.000 0.756 0.244
I49.1 Atrial premature depolarisation
0.000 0.757 0.242
I33.9 Acute endocarditis, unspecified
0.000 0.758 0.241
E10.3 With ophthalmic complications
0.000 0.759 0.241
I20-I25 Ischaemic heart diseases
0.000 0.765 0.235
I50.1 Left ventricular failure
0.000 0.770 0.230
I62 Other nontraumatic intracranial haemorrhage
0.000 0.770 0.230
I63 Cerebral infarction
0.000 0.771 0.229
I44 Atrioventricular and left bundle-branch block
0.000 0.771 0.229
I37.9 Pulmonary valve disorder, unspecified
0.000 0.772 0.228
I37.8 Other pulmonary valve disorders
0.000 0.772 0.228
I37.2 Pulmonary valve stenosis with insufficiency
0.000 0.772 0.228
I37.0 Pulmonary valve stenosis
0.000 0.772 0.228
I10-I15 Hypertensive diseases
0.000 0.777 0.223
I61.5 Intracerebral haemorrhage, intraventricular
0.000 0.778 0.222
I33.0 Acute and subacute infective endocarditis
0.000 0.778 0.222
I45.9 Conduction disorder, unspecified
0.000 0.780 0.220
I30.8 Other forms of acute pericarditis
0.000 0.782 0.218
I30.0 Acute nonspecific idiopathic pericarditis
0.000 0.782 0.218
I30.1 Infective pericarditis
0.000 0.784 0.216
I61.8 Other intracerebral haemorrhage
0.000 0.785 0.215
I44.7 Left bundle-branch block, unspecified
0.000 0.790 0.210
I22 Subsequent myocardial infarction
0.000 0.794 0.206
I61.1 Intracerebral haemorrhage in hemisphere, cortical
0.000 0.794 0.206
I21.4 Acute subendocardial myocardial infarction
0.000 0.795 0.205
I10 Essential (primary) hypertension
0.000 0.796 0.204
I21 Acute myocardial infarction
0.000 0.796 0.204
I31.9 Disease of pericardium, unspecified
0.000 0.797 0.203
I62.0 Subdural haemorrhage (acute) (nontraumatic)
0.000 0.798 0.202
I68 Cerebrovascular disorders in diseases classified elsewhere
0.000 0.801 0.198
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.000 0.801 0.198
I67.2 Cerebral atherosclerosis
0.000 0.801 0.198
E16.2 Hypoglycaemia, unspecified
0.000 0.802 0.198
I31.8 Other specified diseases of pericardium
0.000 0.802 0.197
I31.2 Haemopericardium, not elsewhere classified
0.000 0.802 0.197
I31.1 Chronic constrictive pericarditis
0.000 0.802 0.197
I31.0 Chronic adhesive pericarditis
0.000 0.802 0.197
I20 Angina pectoris
0.000 0.803 0.197
I00-I02 Acute rheumatic fever
0.000 0.803 0.197
E16 Other disorders of pancreatic internal secretion
0.000 0.806 0.194
I61.2 Intracerebral haemorrhage in hemisphere, unspecified
0.000 0.807 0.193
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.000 0.807 0.193
I61.6 Intracerebral haemorrhage, multiple localised
0.000 0.807 0.192
I61.4 Intracerebral haemorrhage in cerebellum
0.000 0.807 0.192
I61.0 Intracerebral haemorrhage in hemisphere, subcortical
0.000 0.807 0.192
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.808 0.191
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.809 0.191
I37.1 Pulmonary valve insufficiency
0.000 0.810 0.190
I67.0 Dissection of cerebral arteries, nonruptured
0.000 0.810 0.189
I67.1 Cerebral aneurysm, nonruptured
0.000 0.812 0.188
D64.9 Anaemia, unspecified
0.000 0.813 0.187
I67.7 Cerebral arteritis, not elsewhere classified
0.000 0.815 0.185
I67.6 Nonpyogenic thrombosis of intracranial venous system
0.000 0.815 0.185
I67.5 Moyamoya disease
0.000 0.815 0.185
I67.4 Hypertensive encephalopathy
0.000 0.815 0.185
I67.3 Progressive vascular leukoencephalopathy
0.000 0.815 0.185
I65.9 Occlusion and stenosis of unspecified precerebral artery
0.000 0.815 0.185
I65.8 Occlusion and stenosis of other precerebral artery
0.000 0.815 0.185
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries
0.000 0.815 0.185
I65.1 Occlusion and stenosis of basilar artery
0.000 0.815 0.185
I65.0 Occlusion and stenosis of vertebral artery
0.000 0.815 0.185
I46.0 Cardiac arrest with successful resuscitation
0.000 0.816 0.183
I64 Stroke, not specified as haemorrhage or infarction
0.000 0.818 0.182
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.000 0.819 0.181
I34 Nonrheumatic mitral valve disorders
0.000 0.821 0.179
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.822 0.178
I46.1 Sudden cardiac death, so described
0.000 0.823 0.177
I20.8 Other forms of angina pectoris
0.000 0.825 0.175
I05-I09 Chronic rheumatic heart diseases
0.000 0.827 0.173
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.000 0.828 0.172
I30.9 Acute pericarditis, unspecified
0.000 0.830 0.170
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.831 0.169
I23 Certain current complications following acute myocardial infarction
0.000 0.831 0.169
I15 Secondary hypertension
0.000 0.832 0.168
E10.9 Without complications
0.000 0.832 0.168
I20.9 Angina pectoris, unspecified
0.000 0.833 0.167
I62.1 Nontraumatic extradural haemorrhage
0.000 0.835 0.165
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.000 0.836 0.164
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.000 0.836 0.164
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.000 0.836 0.164
I44.5 Left posterior fascicular block
0.000 0.836 0.164
I44.4 Left anterior fascicular block
0.000 0.836 0.164
D64 Other anaemias
0.000 0.836 0.164
I63.9 Cerebral infarction, unspecified
0.000 0.836 0.164
I44.0 Atrioventricular block, first degree
0.000 0.838 0.162
I63.8 Other cerebral infarction
0.000 0.839 0.161
I13 Hypertensive heart and renal disease
0.000 0.840 0.160
I44.3 Other and unspecified atrioventricular block
0.000 0.842 0.157
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.847 0.153
I11 Hypertensive heart disease
0.000 0.847 0.153
I24 Other acute ischaemic heart diseases
0.000 0.848 0.152
I62.9 Intracranial haemorrhage (nontraumatic), unspecified
0.000 0.849 0.151
D60-D64 Aplastic and other anaemias
0.000 0.852 0.148
I21.X Presumed acute myicardial infaction (unconfirmed)
0.000 0.853 0.147
I07 Rheumatic tricuspid valve diseases
0.000 0.855 0.145
I61.3 Intracerebral haemorrhage in brain stem
0.000 0.856 0.144
I21.2 Acute transmural myocardial infarction of other sites
0.000 0.856 0.144
I66.9 Occlusion and stenosis of unspecified cerebral artery
0.000 0.857 0.142
I66.8 Occlusion and stenosis of other cerebral artery
0.000 0.857 0.142
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries
0.000 0.857 0.142
I66.3 Occlusion and stenosis of cerebellar arteries
0.000 0.857 0.142
I66.2 Occlusion and stenosis of posterior cerebral artery
0.000 0.857 0.142
I66.1 Occlusion and stenosis of anterior cerebral artery
0.000 0.857 0.142
I66.0 Occlusion and stenosis of middle cerebral artery
0.000 0.857 0.142
I68.8 Other cerebrovascular disorders in diseases classified elsewhere
0.000 0.857 0.142
I68.2 Cerebral arteritis in other diseases classified elsewhere
0.000 0.857 0.142
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere
0.000 0.857 0.142
I68.0 Cerebral amyloid angiopathy
0.000 0.857 0.142
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.000 0.858 0.142
I20.1 Angina pectoris with documented spasm
0.000 0.858 0.142
I02 Rheumatic chorea
0.000 0.858 0.141
I01 Rheumatic fever with heart involvement
0.000 0.858 0.141
I00 Rheumatic fever without mention of heart involvement
0.000 0.858 0.141
I49.9 Cardiac arrhythmia, unspecified
0.000 0.860 0.140
I21.9 Acute myocardial infarction, unspecified
0.000 0.860 0.140
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.861 0.139
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.861 0.139
E16.4 Abnormal secretion of gastrin
0.000 0.861 0.139
E16.3 Increased secretion of glucagon
0.000 0.861 0.139
E16.1 Other hypoglycaemia
0.000 0.861 0.139
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.861 0.139
D62 Acute posthaemorrhagic anaemia
0.000 0.862 0.138
I15.1 Hypertension secondary to other renal disorders
0.000 0.862 0.138
E15 Nondiabetic hypoglycaemic coma
0.000 0.862 0.137
I44.6 Other and unspecified fascicular block
0.000 0.863 0.136
I67.8 Other specified cerebrovascular diseases
0.000 0.868 0.132
I22.8 Subsequent myocardial infarction of other sites
0.000 0.868 0.131
I24.8 Other forms of acute ischaemic heart disease
0.000 0.871 0.129
I34.8 Other nonrheumatic mitral valve disorders
0.000 0.872 0.128
D61 Other aplastic anaemias
0.000 0.873 0.127
I07.1 Tricuspid insufficiency
0.000 0.876 0.124
I06 Rheumatic aortic valve diseases
0.000 0.876 0.124
I05 Rheumatic mitral valve diseases
0.000 0.876 0.124
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.000 0.877 0.122
I23.8 Other current complications following acute myocardial infarction
0.000 0.879 0.121
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.000 0.879 0.121
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.000 0.879 0.121
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.000 0.879 0.121
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.000 0.879 0.121
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.000 0.879 0.121
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.000 0.879 0.121
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.000 0.879 0.121
I15.8 Other secondary hypertension
0.000 0.879 0.121
I15.2 Hypertension secondary to endocrine disorders
0.000 0.879 0.121
I15.0 Renovascular hypertension
0.000 0.879 0.121
I21.3 Acute transmural myocardial infarction of unspecified site
0.000 0.879 0.120
I35 Nonrheumatic aortic valve disorders
0.000 0.881 0.119
I09 Other rheumatic heart diseases
0.000 0.881 0.119
I34.2 Nonrheumatic mitral (valve) stenosis
0.000 0.881 0.119
D64.8 Other specified anaemias
0.000 0.882 0.118
D64.4 Congenital dyserythropoietic anaemia
0.000 0.882 0.118
D64.3 Other sideroblastic anaemias
0.000 0.882 0.118
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.000 0.882 0.118
D64.1 Secondary sideroblastic anaemia due to disease
0.000 0.882 0.118
D64.0 Hereditary sideroblastic anaemia
0.000 0.882 0.118
E50-E64 Other nutritional deficiencies
0.000 0.884 0.116
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.885 0.115
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.000 0.885 0.115
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.885 0.115
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.885 0.115
I47.2 Ventricular tachycardia
0.000 0.886 0.114
D61.9 Aplastic anaemia, unspecified
0.000 0.888 0.112
I24.1 Dressler's syndrome
0.000 0.891 0.109
I11.9 Hypertensive heart disease without (congestive) heart failure
0.000 0.891 0.109
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.891 0.109
I35.1 Aortic (valve) insufficiency
0.000 0.892 0.108
I15.9 Seconday hypertension, unspecified
0.000 0.893 0.106
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.000 0.894 0.106
I34.0 Mitral (valve) insufficiency
0.000 0.894 0.106
I31.3 Pericardial effusion (noninflammatory)
0.000 0.895 0.105
I07.9 Tricuspid valve disease, unspecified
0.000 0.896 0.104
I07.8 Other tricuspid valve diseases
0.000 0.896 0.104
I07.2 Tricuspid stenosis with insufficiency
0.000 0.896 0.104
I07.0 Tricuspid stenosis
0.000 0.896 0.104
I11.0 Hypertensive heart disease with (congestive) heart failure
0.000 0.896 0.104
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.000 0.897 0.103
E20-E35 Disorders of other endocrine glands
0.000 0.897 0.103
I01.9 Acute rheumatic heart disease, unspecified
0.000 0.898 0.101
I01.8 Other acute rheumatic heart disease
0.000 0.898 0.101
I01.2 Acute rheumatic myocarditis
0.000 0.898 0.101
I01.1 Acute rheumatic endocarditis
0.000 0.898 0.101
I01.0 Acute rheumatic pericarditis
0.000 0.898 0.101
I02.9 Rheumatic chorea without heart involvement
0.000 0.898 0.101
I02.0 Rheumatic chorea with heart involvement
0.000 0.898 0.101
E40-E46 Malnutrition
0.001 0.899 0.100
I73 Other peripheral vascular diseases
0.000 0.902 0.098
I05.1 Rheumatic mitral insufficiency
0.000 0.902 0.098
I12 Hypertensive renal disease
0.000 0.903 0.097
I73.9 Peripheral vascular disease, unspecified
0.000 0.903 0.097
I05.0 Mitral stenosis
0.000 0.904 0.096
I69 Sequelae of cerebrovascular disease
0.000 0.909 0.091
D61.8 Other specified aplastic anaemias
0.000 0.909 0.091
D61.3 Idiopathic aplastic anaemia
0.000 0.909 0.091
D61.2 Aplastic anaemia due to other external agents
0.000 0.909 0.091
D61.1 Drug-induced aplastic anaemia
0.000 0.909 0.091
D61.0 Constitutional aplastic anaemia
0.000 0.909 0.091
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.910 0.090
I06.9 Rheumatic aortic valve disease, unspecified
0.000 0.910 0.089
I06.8 Other rheumatic aortic valve diseases
0.000 0.910 0.089
I06.2 Rheumatic aortic stenosis with insufficiency
0.000 0.910 0.089
I06.1 Rheumatic aortic insufficiency
0.000 0.910 0.089
I06.0 Rheumatic aortic stenosis
0.000 0.910 0.089
I05.8 Other mitral valve diseases
0.000 0.911 0.089
E23 Hypofunction and other disorders of pituitary gland
0.000 0.911 0.089
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.911 0.088
D63 Anaemia in chronic diseases classified elsewhere
0.000 0.912 0.088
I05.2 Mitral stenosis with insufficiency
0.000 0.913 0.087
I09.8 Other specified rheumatic heart diseases
0.000 0.915 0.085
I09.2 Chronic rheumatic pericarditis
0.000 0.915 0.085
I09.1 Rheumatic diseases of endocardium, valve unspecified
0.000 0.915 0.085
I09.0 Rheumatic myocarditis
0.000 0.915 0.085
E65-E68 Obesity and other hyperalimentation
0.000 0.915 0.085
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.917 0.083
E63 Other nutritional deficiencies
0.000 0.917 0.083
E56 Other vitamin deficiencies
0.000 0.917 0.083
E51 Thiamine deficiency
0.000 0.917 0.083
E50 Vitamin A deficiency
0.000 0.917 0.083
E60 Dietary zinc deficiency
0.000 0.917 0.083
E59 Dietary selenium deficiency
0.000 0.917 0.083
E58 Dietary calcium deficiency
0.000 0.917 0.083
E54 Ascorbic acid deficiency
0.000 0.917 0.083
E52 Niacin deficiency [pellagra]
0.000 0.917 0.083
I78 Diseases of capillaries
0.000 0.917 0.083
E61 Deficiency of other nutrient elements
0.000 0.918 0.082
E23.0 Hypopituitarism
0.000 0.918 0.082
I09.9 Rheumatic heart disease, unspecified
0.000 0.920 0.079
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.920 0.079
I44.2 Atrioventricular block, complete
0.000 0.921 0.079
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.000 0.922 0.078
E00-E07 Disorders of thyroid gland
0.000 0.923 0.077
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.000 0.923 0.077
D60.9 Acquired pure red cell aplasia, unspecified
0.000 0.924 0.076
D60.8 Other acquired pure red cell aplasias
0.000 0.924 0.076
D60.1 Transient acquired pure red cell aplasia
0.000 0.924 0.076
D60.0 Chronic acquired pure red cell aplasia
0.000 0.924 0.076
E55 Vitamin D deficiency
0.000 0.924 0.075
I20.0 Unstable angina
0.000 0.925 0.075
I95-I99 Other and unspecified disorders of the circulatory system
0.000 0.925 0.074
I21.0 Acute transmural myocardial infarction of anterior wall
0.000 0.926 0.074
I28 Other diseases of pulmonary vessels
0.000 0.926 0.074
E29 Testicular dysfunction
0.000 0.926 0.074
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.926 0.074
E32 Diseases of thymus
0.000 0.926 0.074
E31 Polyglandular dysfunction
0.000 0.926 0.074
E30 Disorders of puberty, not elsewhere classified
0.000 0.926 0.074
E25 Adrenogenital disorders
0.000 0.926 0.074
E53 Deficiency of other B group vitamins
0.000 0.926 0.074
E24 Cushing's syndrome
0.000 0.926 0.074
E27 Other disorders of adrenal gland
0.000 0.926 0.074
E20 Hypoparathyroidism
0.000 0.927 0.073
I71 Aortic aneurysm and dissection
0.000 0.928 0.072
E23.2 Diabetes insipidus
0.000 0.928 0.072
E44 Protein-energy malnutrition of moderate and mild degree
0.001 0.928 0.072
E45 Retarded development following protein-energy malnutrition
0.001 0.928 0.072
E43 Unspecified severe protein-energy malnutrition
0.001 0.928 0.072
E42 Marasmic kwashiorkor
0.001 0.928 0.072
E41 Nutritional marasmus
0.001 0.928 0.072
E40 Kwashiorkor
0.001 0.928 0.072
I73.1 Thromboangiitis obliterans [Buerger]
0.000 0.929 0.071
D80-D89 Certain disorders involving the immune mechanism
0.000 0.930 0.070
E06 Thyroiditis
0.000 0.930 0.070
I73.8 Other specified peripheral vascular diseases
0.000 0.931 0.069
I05.9 Mitral valve disease, unspecified
0.000 0.931 0.069
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.000 0.931 0.069
E34 Other endocrine disorders
0.000 0.933 0.067
I21.1 Acute transmural myocardial infarction of inferior wall
0.000 0.933 0.067
I70 Atherosclerosis
0.000 0.933 0.067
I78.0 Hereditary haemorrhagic telangiectasia
0.000 0.933 0.066
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.000 0.934 0.065
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.934 0.066
I71.3 Abdominal aortic aneurysm, ruptured
0.000 0.935 0.065
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.935 0.065
I79.1 Aortitis in diseases classified elsewhere
0.000 0.935 0.065
I79.0 Aneurysm of aorta in diseases classified elsewhere
0.000 0.935 0.065
I69.1 Sequelae of intracerebral haemorrhage
0.000 0.935 0.064
I69.0 Sequelae of subarachnoid haemorrhage
0.000 0.936 0.064
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.936 0.064
E23.1 Drug-induced hypopituitarism
0.000 0.936 0.064
O02.1 Missed abortion
0.064 0.936 0.000
I60 Subarachnoid haemorrhage
0.000 0.936 0.063
E07 Other disorders of thyroid
0.000 0.936 0.063
E26 Hyperaldosteronism
0.000 0.937 0.063
D63.1 Anaemia in other chronic diseases classified elsewhere
0.000 0.937 0.063
D68 Other coagulation defects
0.000 0.937 0.063
I08 Multiple valve diseases
0.000 0.937 0.063
E06.3 Autoimmune thyroiditis
0.000 0.937 0.063
E67 Other hyperalimentation
0.000 0.939 0.061
E68 Sequelae of hyperalimentation
0.000 0.939 0.061
D86 Sarcoidosis
0.000 0.939 0.061
I44.1 Atrioventricular block, second degree
0.000 0.939 0.060
E22 Hyperfunction of pituitary gland
0.000 0.939 0.061
E50.9 Vitamin A deficiency, unspecified
0.000 0.940 0.060
E50.8 Other manifestations of vitamin A deficiency
0.000 0.940 0.060
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.940 0.060
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.940 0.060
E50.5 Vitamin A deficiency with night blindness
0.000 0.940 0.060
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.940 0.060
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.940 0.060
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.940 0.060
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.940 0.060
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.940 0.060
E51.9 Thiamine deficiency, unspecified
0.000 0.940 0.060
E51.8 Other manifestations of thiamine deficiency
0.000 0.940 0.060
E51.2 Wernicke's encephalopathy
0.000 0.940 0.060
E51.1 Beriberi
0.000 0.940 0.060
E56.9 Vitamin deficiency, unspecified
0.000 0.940 0.060
E56.8 Deficiency of other vitamins
0.000 0.940 0.060
E56.1 Deficiency of vitamin K
0.000 0.940 0.060
E56.0 Deficiency of vitamin E
0.000 0.940 0.060
E63.9 Nutritional deficiency, unspecified
0.000 0.940 0.060
E63.8 Other specified nutritional deficiencies
0.000 0.940 0.060
E63.1 Imbalance of constituents of food intake
0.000 0.940 0.060
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.940 0.060
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.940 0.060
E64.8 Sequelae of other nutritional deficiencies
0.000 0.940 0.060
E64.3 Sequelae of rickets
0.000 0.940 0.060
E64.2 Sequelae of vitamin C deficiency
0.000 0.940 0.060
E64.1 Sequelae of vitamin A deficiency
0.000 0.940 0.060
E64.0 Sequelae of protein-energy malnutrition
0.000 0.940 0.060
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.000 0.940 0.060
E28 Ovarian dysfunction
0.000 0.940 0.060
I34.1 Mitral (valve) prolapse
0.000 0.940 0.059
I78.9 Disease of capillaries, unspecified
0.000 0.940 0.059
E61.9 Deficiency of nutrient element, unspecified
0.000 0.941 0.059
E61.8 Deficiency of other specified nutrient elements
0.000 0.941 0.059
E61.7 Deficiency of multiple nutrient elements
0.000 0.941 0.059
E61.6 Vanadium deficiency
0.000 0.941 0.059
E61.5 Molybdenum deficiency
0.000 0.941 0.059
E61.4 Chromium deficiency
0.000 0.941 0.059
E61.3 Manganese deficiency
0.000 0.941 0.059
E61.2 Magnesium deficiency
0.000 0.941 0.059
E61.0 Copper deficiency
0.000 0.941 0.059
D68.9 Coagulation defect, unspecified
0.000 0.941 0.059
I78.8 Other diseases of capillaries
0.000 0.941 0.059
D66 Hereditary factor VIII deficiency
0.000 0.942 0.058
D63.8 Anaemia in other chronic diseases classified elsewhere
0.000 0.942 0.058
E61.1 Iron deficiency
0.000 0.942 0.058
E06.9 Thyroiditis, unspecified
0.000 0.944 0.056
E23.6 Other disorders of pituitary gland
0.000 0.944 0.056
I78.1 Naevus, nonneoplastic
0.000 0.944 0.056
E27.9 Disorder of adrenal gland, unspecified
0.000 0.944 0.056
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.944 0.055
E00 Congenital iodine-deficiency syndrome
0.000 0.944 0.055
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.944 0.055

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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