TreeWAS – Variant ID: rs11000217

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
K20-K31 Diseases of oesophagus, stomach and duodenum	1.000	0.000
Chapter IX Diseases of the circulatory system	1.000	0.000
# Top node	1.000	0.000
I30-I52 Other forms of heart disease	1.000	0.000
Chapter XI Diseases of the digestive system	1.000	0.000
K22 Other diseases of oesophagus	0.999	0.001
Chapter X Diseases of the respiratory system	0.998	0.002
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.996	0.004
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.995	0.005
Chapter XII Diseases of the skin and subcutaneous tissue	0.993	0.007
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.992	0.008
K20 Oesophagitis	0.992	0.008
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	0.991	0.009
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.988	0.012
K22.1 Ulcer of oesophagus	0.988	0.012
K21 Gastro-oesophageal reflux disease	0.981	0.019
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.980	0.020
M50-M54 Other dorsopathies	0.979	0.021
L80-L99 Other disorders of the skin and subcutaneous tissue	0.978	0.022
K21.9 Gastro-oesophageal reflux disease without oesophagitis	0.976	0.024
K22.7 Barrett's oesophagus	0.971	0.029
Chapter IV Endocrine, nutritional and metabolic diseases	0.968	0.032
I80 Phlebitis and thrombophlebitis	0.966	0.034
M45-M49 Spondylopathies	0.960	0.040
Chapter VII Diseases of the eye and adnexa	0.960	0.040
Chapter I Certain infectious and parasitic diseases	0.952	0.048
M54 Dorsalgia	0.952	0.048
T81 Complications of procedures, not elsewhere classified	0.948	0.052
I34 Nonrheumatic mitral valve disorders	0.943	0.057
I51 Complications and ill-defined descriptions of heart disease	0.943	0.057
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities	0.941	0.059
I84 Haemorrhoids	0.938	0.062
T81.4 Infection following a procedure, not elsewhere classified	0.936	0.064
L82 Seborrhoeic keratosis	0.935	0.065
J95-J99 Other diseases of the respiratory system	0.932	0.068
M47 Spondylosis	0.926	0.074
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis	0.924	0.076
D60-D64 Aplastic and other anaemias	0.922	0.078
D50-D53 Nutritional anaemias	0.922	0.078
I49 Other cardiac arrhythmias	0.921	0.079
I46 Cardiac arrest	0.921	0.079
Chapter VIII Diseases of the ear and mastoid process	0.920	0.080
K26 Duodenal ulcer	0.917	0.083
K40-K46 Hernia	0.911	0.089
E00-E07 Disorders of thyroid gland	0.907	0.093
I60-I69 Cerebrovascular diseases	0.907	0.093
K50-K52 Noninfective enteritis and colitis	0.906	0.094
I50 Heart failure	0.905	0.095
I35 Nonrheumatic aortic valve disorders	0.904	0.096
J30-J39 Other diseases of upper respiratory tract	0.903	0.097
M54.5 Low back pain	0.902	0.098
I42 Cardiomyopathy	0.896	0.104
I20-I25 Ischaemic heart diseases	0.896	0.104
I34.0 Mitral (valve) insufficiency	0.890	0.110
H30-H36 Disorders of choroid and retina	0.883	0.117
B95-B98 Bacterial, viral and other infectious agents	0.883	0.117
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.881	0.119
M47.8 Other spondylosis	0.881	0.119
I95-I99 Other and unspecified disorders of the circulatory system	0.879	0.121
R50-R69 General symptoms and signs	0.876	0.124
J98 Other respiratory disorders	0.869	0.131
J20-J22 Other acute lower respiratory infections	0.869	0.131
E20-E35 Disorders of other endocrine glands	0.867	0.133
I51.8 Other ill-defined heart diseases	0.863	0.137
R00-R09 Symptoms and signs involving the circulatory and respiratory systems	0.861	0.139
I46.0 Cardiac arrest with successful resuscitation	0.857	0.143
L00-L08 Infections of the skin and subcutaneous tissue	0.856	0.144
H43-H45 Disorders of vitreous body and globe	0.854	0.146
K22.2 Oesophageal obstruction	0.853	0.147
Chapter XIV Diseases of the genitourinary system	0.852	0.148
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.852	0.148
R91 Abnormal findings on diagnostic imaging of lung	0.850	0.150
I47 Paroxysmal tachycardia	0.845	0.155
I84.2 Internal haemorrhoids without complication	0.843	0.157
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters	0.843	0.157
I21 Acute myocardial infarction	0.841	0.159
I35.0 Aortic (valve) stenosis	0.841	0.159
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems	0.840	0.160
J40-J47 Chronic lower respiratory diseases	0.837	0.163
K30 Dyspepsia	0.836	0.164
K44 Diaphragmatic hernia	0.835	0.165
J80-J84 Other respiratory diseases principally affecting the interstitium	0.835	0.165
M54.2 Cervicalgia	0.833	0.167
L91 Hypertrophic disorders of skin	0.832	0.168
K22.0 Achalasia of cardia	0.831	0.168
M50 Cervical disk disorders	0.829	0.171
E03 Other hypothyroidism	0.825	0.175
J09-J18 Influenza and pneumonia	0.825	0.175
D51 Vitamin B12 deficiency anaemia	0.824	0.176
K50 Crohn's disease [regional enteritis]	0.823	0.177
K40 Inguinal hernia	0.822	0.178
S20-S29 Injuries to the thorax	0.822	0.178
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue	0.822	0.178
H53-H54 Visual disturbances and blindness	0.820	0.180
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.818	0.182
I64 Stroke, not specified as haemorrhage or infarction	0.818	0.182
R59 Enlarged lymph nodes	0.817	0.183
I21.9 Acute myocardial infarction, unspecified	0.816	0.184
H65-H75 Diseases of middle ear and mastoid	0.815	0.185
D64 Other anaemias	0.814	0.186
M47.82 Other spondylosis (Cervical region)	0.813	0.187
N30-N39 Other diseases of urinary system	0.810	0.190
I49.0 Ventricular fibrillation and flutter	0.810	0.190
E50-E64 Other nutritional deficiencies	0.807	0.192
K25 Gastric ulcer	0.806	0.194
I84.8 Unspecified haemorrhoids with other complications	0.805	0.195
E70-E90 Metabolic disorders	0.804	0.196
K31 Other diseases of stomach and duodenum	0.801	0.199
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.800	0.200
L20-L30 Dermatitis and eczema	0.800	0.200
I05-I09 Chronic rheumatic heart diseases	0.799	0.201
D80-D89 Certain disorders involving the immune mechanism	0.797	0.203
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.795	0.205
D50 Iron deficiency anaemia	0.794	0.206
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour	0.793	0.207
M20-M25 Other joint disorders	0.793	0.207
I95 Hypotension	0.793	0.207
I50.1 Left ventricular failure	0.792	0.208
K40.2 Bilateral inguinal hernia, without obstruction or gangrene	0.791	0.209
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.790	0.210
K26.9 Unspecified as acute or chronic, without haemorrhage or perforation	0.785	0.215
S40-S49 Injuries to the shoulder and upper arm	0.785	0.215
M47.9 Spondylosis, unspecified	0.785	0.215
N17-N19 Renal failure	0.785	0.215
M54.56 Low back pain (Lumbar region)	0.783	0.217
A00-A09 Intestinal infectious diseases	0.783	0.217
L50-L54 Urticaria and erythema	0.783	0.217
Chapter VI Diseases of the nervous system	0.782	0.218
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.781	0.219
K44.9 Diaphragmatic hernia without obstruction or gangrene	0.781	0.219
M40-M43 Deforming dorsopathies	0.780	0.220
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters	0.780	0.220
J22 Unspecified acute lower respiratory infection	0.776	0.224
R60 Oedema, not elsewhere classified	0.773	0.227
J98.1 Pulmonary collapse	0.772	0.228
E05 Thyrotoxicosis [hyperthyroidism]	0.772	0.228
K26.7 Chronic without haemorrhage or perforation	0.771	0.229
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities	0.769	0.231
J32 Chronic sinusitis	0.769	0.231
R59.0 Localised enlarged lymph nodes	0.767	0.233
I42.2 Other hypertrophic cardiomyopathy	0.766	0.234
T83.0 Mechanical complication of urinary (indwelling) catheter	0.766	0.234
Chapter V Mental and behavioural disorders	0.765	0.235
E03.9 Hypothyroidism, unspecified	0.765	0.235
J34 Other disorders of nose and nasal sinuses	0.765	0.235
H35 Other retinal disorders	0.763	0.237
H43 Disorders of vitreous body	0.761	0.239
I82 Other venous embolism and thrombosis	0.760	0.240
I51.7 Cardiomegaly	0.759	0.241
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.759	0.241
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.758	0.242
D63 Anaemia in chronic diseases classified elsewhere	0.757	0.243
I44 Atrioventricular and left bundle-branch block	0.755	0.245
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency	0.755	0.245
I84.6 Residual haemorrhoidal skin tags	0.754	0.246
H90-H95 Other disorders of ear	0.752	0.248
L97 Ulcer of lower limb, not elsewhere classified	0.751	0.249
Chapter XXII Codes for special purposes	0.750	0.250
L90 Atrophic disorders of skin	0.750	0.250
I84.7 Unspecified thrombosed haemorrhoids	0.749	0.250
H10-H13 Disorders of conjunctiva	0.749	0.251
R03 Abnormal blood-pressure reading, without diagnosis	0.749	0.251
R47-R49 Symptoms and signs involving speech and voice	0.748	0.252
K80-K87 Disorders of gallbladder, biliary tract and pancreas	0.748	0.252
T85 Complications of other internal prosthetic devices, implants and grafts	0.747	0.252
I69 Sequelae of cerebrovascular disease	0.747	0.253
M54.22 Cervicalgia (Cervical region)	0.747	0.253
M54.4 Lumbago with sciatica	0.747	0.253
M54.58 Low back pain (Sacral and sacrococcygeal region)	0.745	0.255
R80-R82 Abnormal findings on examination of urine, without diagnosis	0.745	0.255
L84 Corns and callosities	0.745	0.255
I51.9 Heart disease, unspecified	0.745	0.255
M51 Other intervertebral disk disorders	0.744	0.256
E21.0 Primary hyperparathyroidism	0.744	0.256
B35-B49 Mycoses	0.744	0.256
D50.9 Iron deficiency anaemia, unspecified	0.743	0.257
S90-S99 Injuries to the ankle and foot	0.743	0.257
D62 Acute posthaemorrhagic anaemia	0.741	0.259
J00-J06 Acute upper respiratory infections	0.740	0.260
R00 Abnormalities of heart beat	0.740	0.260
I95.9 Hypotension, unspecified	0.740	0.260
D70-D77 Other diseases of blood and blood-forming organs	0.739	0.261
M54.59 Low back pain (Site unspecified)	0.737	0.263
I34.1 Mitral (valve) prolapse	0.737	0.263
D64.9 Anaemia, unspecified	0.737	0.263
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.737	0.263
K22.4 Dyskinesia of oesophagus	0.737	0.263
I35.9 Aortic valve disorder, unspecified	0.736	0.264
T66-T78 Other and unspecified effects of external causes	0.736	0.264
J99 Respiratory disorders in diseases classified elsewhere	0.735	0.264
M45 Ankylosing spondylitis	0.734	0.266
I89 Other non-infective disorders of lymphatic vessels and lymph nodes	0.733	0.266
I42.0 Dilated cardiomyopathy	0.733	0.267
L92 Granulomatous disorders of skin and subcutaneous tissue	0.733	0.267
M70-M79 Other soft tissue disorders	0.732	0.268
T90 Sequelae of injuries of head	0.731	0.269
K65-K67 Diseases of peritoneum	0.731	0.269
R26 Abnormalities of gait and mobility	0.730	0.270
R21 Rash and other nonspecific skin eruption	0.729	0.271
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts	0.728	0.272
K51 Ulcerative colitis	0.727	0.273
N00-N08 Glomerular diseases	0.727	0.273
I86 Varicose veins of other sites	0.726	0.274
A80-A89 Viral infections of the central nervous system	0.726	0.274
J60-J70 Lung diseases due to external agents	0.726	0.274
L89 Decubitus ulcer	0.726	0.274
L81 Other disorders of pigmentation	0.725	0.275
R63 Symptoms and signs concerning food and fluid intake	0.725	0.275
I20 Angina pectoris	0.725	0.275
M47.80 Other spondylosis (Multiple sites in spine)	0.725	0.275
I50.9 Heart failure, unspecified	0.725	0.275
M46 Other inflammatory spondylopathies	0.724	0.276
I49.8 Other specified cardiac arrhythmias	0.724	0.276
I49.9 Cardiac arrhythmia, unspecified	0.723	0.277
R10-R19 Symptoms and signs involving the digestive system and abdomen	0.723	0.277
T88 Other complications of surgical and medical care, not elsewhere classified	0.721	0.278
M86-M90 Other osteopathies	0.721	0.279
J98.0 Diseases of bronchus, not elsewhere classified	0.721	0.279
R61 Hyperhidrosis	0.721	0.279
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.720	0.280
H34 Retinal vascular occlusions	0.720	0.280
S60-S69 Injuries to the wrist and hand	0.720	0.280
T81.3 Disruption of operation wound, not elsewhere classified	0.719	0.281
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.719	0.281
K31.7 Polyp of stomach and duodenum	0.719	0.281
K50.9 Crohn's disease, unspecified	0.718	0.282
K28 Gastrojejunal ulcer	0.717	0.283
K23 Disorders of oesophagus in diseases classified elsewhere	0.717	0.283
I00-I02 Acute rheumatic fever	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
I52 Other heart disorders in diseases classified elsewhere	0.717	0.283
I48 Atrial fibrillation and flutter	0.717	0.283
I43 Cardiomyopathy in diseases classified elsewhere	0.717	0.283
I41 Myocarditis in diseases classified elsewhere	0.717	0.283
I40 Acute myocarditis	0.717	0.283
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.717	0.283
I37 Pulmonary valve disorders	0.717	0.283
I36 Nonrheumatic tricuspid valve disorders	0.717	0.283
I33 Acute and subacute endocarditis	0.717	0.283
I32 Pericarditis in diseases classified elsewhere	0.717	0.283
I30 Acute pericarditis	0.717	0.283
K22.6 Gastro-oesophageal laceration-haemorrhage syndrome	0.716	0.284
K22.5 Diverticulum of oesophagus, acquired	0.716	0.284
K22.3 Perforation of oesophagus	0.716	0.284
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.716	0.284
L85 Other epidermal thickening	0.716	0.284
R09 Other symptoms and signs involving the circulatory and respiratory systems	0.715	0.284
S00-S09 Injuries to the head	0.715	0.285
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.714	0.286
M91-M94 Chondropathies	0.714	0.286
M60-M63 Disorders of muscles	0.714	0.286
M00-M03 Infectious arthropathies	0.714	0.286
M05-M14 Inflammatory polyarthropathies	0.714	0.286
I45 Other conduction disorders	0.714	0.286
N32 Other disorders of bladder	0.714	0.286
J90-J94 Other diseases of pleura	0.713	0.287
T79-T79 Certain early complications of trauma	0.713	0.287
T33-T35 Frostbite	0.713	0.287
T26-T28 Burns and corrosions confined to eye and internal organs	0.713	0.287
T20-T25 Burns and corrosions of external body surface, specified by site	0.713	0.287
T15-T19 Effects of foreign body entering through natural orifice	0.713	0.287
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.713	0.287
T00-T07 Injuries involving multiple body regions	0.713	0.287
S10-S19 Injuries to the neck	0.713	0.287
I84.3 External thrombosed haemorrhoids	0.713	0.287
L10-L14 Bullous disorders	0.712	0.288
R94 Abnormal results of function studies	0.712	0.288
I88 Nonspecific lymphadenitis	0.711	0.289
I87 Other disorders of veins	0.711	0.289
I81 Portal vein thrombosis	0.711	0.289
M54.57 Low back pain (Lumbosacral region)	0.711	0.289
J84 Other interstitial pulmonary diseases	0.711	0.289
R95-R99 Ill-defined and unknown causes of mortality	0.711	0.289
R93 Abnormal findings on diagnostic imaging of other body structures	0.710	0.289
S70-S79 Injuries to the hip and thigh	0.709	0.291
D55-D59 Haemolytic anaemias	0.708	0.292
H36 Retinal disorders in diseases classified elsewhere	0.708	0.292
M50.0 Cervical disk disorder with myelopathy	0.708	0.292
K26.4 Chronic or unspecified with haemorrhage	0.708	0.292
M80-M85 Disorders of bone density and structure	0.706	0.293
I60 Subarachnoid haemorrhage	0.706	0.294
I49.3 Ventricular premature depolarisation	0.704	0.296
L60-L75 Disorders of skin appendages	0.703	0.297
T87 Complications peculiar to reattachment and amputation	0.703	0.297
T86 Failure and rejection of transplanted organs and tissues	0.703	0.297
T80 Complications following infusion, transfusion and therapeutic injection	0.703	0.297
M53 Other dorsopathies, not elsewhere classified	0.702	0.298
K22.9 Disease of oesophagus, unspecified	0.701	0.299
J45 Asthma	0.701	0.299
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere	0.701	0.299
L95 Vasculitis limited to skin, not elsewhere classified	0.701	0.299
L94 Other localised connective tissue disorders	0.701	0.299
L93 Lupus erythematosus	0.701	0.299
L87 Transepidermal elimination disorders	0.701	0.299
L88 Pyoderma gangrenosum	0.701	0.299
L86 Keratoderma in diseases classified elsewhere	0.701	0.299
L83 Acanthosis nigricans	0.701	0.299
L80 Vitiligo	0.701	0.299
I38 Endocarditis, valve unspecified	0.701	0.299
B25-B34 Other viral diseases	0.701	0.299
J39 Other diseases of upper respiratory tract	0.700	0.300
R60.0 Localised oedema	0.699	0.301
A04 Other bacterial intestinal infections	0.698	0.302
K27 Peptic ulcer, site unspecified	0.698	0.302
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis	0.696	0.304
L91.0 Keloid scar	0.696	0.304
E40-E46 Malnutrition	0.694	0.306
E78.5 Hyperlipidaemia, unspecified	0.693	0.307
I80.9 Phlebitis and thrombophlebitis of unspecified site	0.693	0.307
I80.8 Phlebitis and thrombophlebitis of other sites	0.693	0.307
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified	0.693	0.307
I80.1 Phlebitis and thrombophlebitis of femoral vein	0.693	0.307
J30 Vasomotor and allergic rhinitis	0.691	0.309
I46.9 Cardiac arrest, unspecified	0.690	0.310
H60-H62 Diseases of external ear	0.690	0.310
I85 Oesophageal varices	0.689	0.311
M47.89 Other spondylosis (Site unspecified)	0.689	0.311
M49 Spondylopathies in diseases classified elsewhere	0.688	0.311
H55-H59 Other disorders of eye and adnexa	0.688	0.312
H46-H48 Disorders of optic nerve and visual pathways	0.688	0.312
B97 Viral agents as the cause of diseases classified to other chapters	0.688	0.312
L03 Cellulitis	0.687	0.313
M65-M68 Disorders of synovium and tendon	0.685	0.315
N18 Chronic renal failure	0.685	0.315
I50.0 Congestive heart failure	0.684	0.315
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.684	0.316
E07 Other disorders of thyroid	0.684	0.316
I47.1 Supraventricular tachycardia	0.684	0.316
N30 Cystitis	0.683	0.317
B99-B99 Other infectious diseases	0.683	0.317
B90-B94 Sequelae of infectious and parasitic diseases	0.683	0.317
B85-B89 Pediculosis, acariasis and other infestations	0.683	0.317
B65-B83 Helminthiases	0.683	0.317
B50-B64 Protozoal diseases	0.683	0.317
B20-B24 Human immunodeficiency virus [HIV] disease	0.683	0.317
B15-B19 Viral hepatitis	0.683	0.317
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.683	0.317
A75-A79 Rickettsioses	0.683	0.317
A70-A74 Other diseases caused by chlamydiae	0.683	0.317
A65-A69 Other spirochaetal diseases	0.683	0.317
A50-A64 Infections with a predominantly sexual mode of transmission	0.683	0.317
A20-A28 Certain zoonotic bacterial diseases	0.683	0.317
A15-A19 Tuberculosis	0.683	0.317
M54.8 Other dorsalgia	0.682	0.318
M54.6 Pain in thoracic spine	0.682	0.318
M54.1 Radiculopathy	0.682	0.318
M54.0 Panniculitis affecting regions of neck and back	0.682	0.318
M48 Other spondylopathies	0.682	0.318
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified	0.682	0.318
E06 Thyroiditis	0.682	0.318
T81.9 Unspecified complication of procedure	0.680	0.320
T81.7 Vascular complications following a procedure, not elsewhere classified	0.680	0.320
T81.6 Acute reaction to foreign substance accidentally left during a procedure	0.680	0.320
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure	0.680	0.320
T81.1 Shock during or resulting from a procedure, not elsewhere classified	0.680	0.320
I47.2 Ventricular tachycardia	0.680	0.320
J18 Pneumonia, organism unspecified	0.680	0.320
J98.4 Other disorders of lung	0.679	0.321
S22 Fracture of rib(s), sternum and thoracic spine	0.679	0.321
Chapter XXI Factors influencing health status and contact with health services	0.679	0.321
I63 Cerebral infarction	0.679	0.321
L08 Other local infections of skin and subcutaneous tissue	0.678	0.322
N17 Acute renal failure	0.678	0.322
I34.9 Nonrheumatic mitral valve disorder, unspecified	0.676	0.324
I34.8 Other nonrheumatic mitral valve disorders	0.676	0.324
I34.2 Nonrheumatic mitral (valve) stenosis	0.676	0.324
I51.6 Cardiovascular disease, unspecified	0.676	0.324
I51.5 Myocardial degeneration	0.676	0.324
I51.4 Myocarditis, unspecified	0.676	0.324
I51.3 Intracardiac thrombosis, not elsewhere classified	0.676	0.324
I51.2 Rupture of papillary muscle, not elsewhere classified	0.676	0.324
I51.1 Rupture of chordae tendineae, not elsewhere classified	0.676	0.324
I51.0 Cardiac septal defect, acquired	0.676	0.324
I21.2 Acute transmural myocardial infarction of other sites	0.676	0.324
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts	0.676	0.324
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.676	0.324
J38 Diseases of vocal cords and larynx, not elsewhere classified	0.675	0.325
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.675	0.325
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.675	0.325
M23 Internal derangement of knee	0.674	0.326
N70-N77 Inflammatory diseases of female pelvic organs	0.673	0.327
I84.0 Internal thrombosed haemorrhoids	0.673	0.327
K41 Femoral hernia	0.672	0.328
I42.9 Cardiomyopathy, unspecified	0.670	0.330
F40-F48 Neurotic, stress-related and somatoform disorders	0.670	0.330
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters	0.669	0.331
J96 Respiratory failure, not elsewhere classified	0.668	0.331
J95 Postprocedural respiratory disorders, not elsewhere classified	0.668	0.331
I84.5 External haemorrhoids without complication	0.668	0.332
E53 Deficiency of other B group vitamins	0.668	0.332
H53 Visual disturbances	0.668	0.332
H54 Blindness and low vision	0.668	0.332
R05 Cough	0.667	0.333
B95.4 Other streptococcus as the cause of diseases classified to other chapters	0.667	0.333
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status	0.667	0.333
H80-H83 Diseases of inner ear	0.666	0.334
K35-K38 Diseases of appendix	0.665	0.335
M47.2 Other spondylosis with radiculopathy	0.664	0.336
M47.1 Other spondylosis with myelopathy	0.664	0.336
M47.0 Anterior spinal and vertebral artery compression syndromes	0.664	0.336
R90 Abnormal findings on diagnostic imaging of central nervous system	0.662	0.338
R92 Abnormal findings on diagnostic imaging of breast	0.662	0.338
M54.9 Dorsalgia, unspecified	0.662	0.338
M54.3 Sciatica	0.662	0.338
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.661	0.339
R19 Other symptoms and signs involving the digestive system and abdomen	0.661	0.339
D61 Other aplastic anaemias	0.661	0.339
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.661	0.339
D53 Other nutritional anaemias	0.661	0.339
D52 Folate deficiency anaemia	0.661	0.339
K25.9 Unspecified as acute or chronic, without haemorrhage or perforation	0.661	0.339
I49.4 Other and unspecified premature depolarisation	0.660	0.340
I49.2 Junctional premature depolarisation	0.660	0.340
I49.1 Atrial premature depolarisation	0.660	0.340
I46.1 Sudden cardiac death, so described	0.660	0.340
R11 Nausea and vomiting	0.660	0.340
I69.3 Sequelae of cerebral infarction	0.660	0.340
D86 Sarcoidosis	0.660	0.340
M24 Other specific joint derangements	0.659	0.341
L02 Cutaneous abscess, furuncle and carbuncle	0.659	0.341
S80-S89 Injuries to the knee and lower leg	0.658	0.342
K26.6 Chronic or unspecified with both haemorrhage and perforation	0.657	0.343
K26.5 Chronic or unspecified with perforation	0.657	0.343
K26.3 Acute without haemorrhage or perforation	0.657	0.343
K26.2 Acute with both haemorrhage and perforation	0.657	0.343
K26.1 Acute with perforation	0.657	0.343
K26.0 Acute with haemorrhage	0.657	0.343
R52 Pain, not elsewhere classified	0.657	0.343
I21.4 Acute subendocardial myocardial infarction	0.657	0.343
H44 Disorders of globe	0.657	0.343
R03.1 Nonspecific low blood-pressure reading	0.656	0.344
K46 Unspecified abdominal hernia	0.656	0.344
H73 Other disorders of tympanic membrane	0.656	0.344
H71 Cholesteatoma of middle ear	0.656	0.344
I08 Multiple valve diseases	0.655	0.344
Chapter XX External causes of morbidity and mortality	0.655	0.345
T36-T50 Poisoning by drugs, medicaments and biological substances	0.654	0.346
K45 Other abdominal hernia	0.653	0.347
Z88 Personal history of allergy to drugs, medicaments and biologocal substances	0.653	0.347
K00-K14 Diseases of oral cavity, salivary glands and jaws	0.653	0.347
K50.0 Crohn's disease of small intestine	0.653	0.347
J36 Peritonsillar abscess	0.653	0.347
N39 Other disorders of urinary system	0.653	0.347
H74 Other disorders of middle ear and mastoid	0.652	0.348
L91.8 Other hypertrophic disorders of skin	0.651	0.349
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.650	0.349
E00 Congenital iodine-deficiency syndrome	0.650	0.349
E02 Subclinical iodine-deficiency hypothyroidism	0.650	0.349
I68 Cerebrovascular disorders in diseases classified elsewhere	0.650	0.349
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.650	0.349
I62 Other nontraumatic intracranial haemorrhage	0.650	0.349
M79 Other soft tissue disorders, not elsewhere classified	0.650	0.350
S32 Fracture of lumbar spine and pelvis	0.649	0.351
R02 Gangrene, not elsewhere classified	0.649	0.351
I35.8 Other aortic valve disorders	0.648	0.352
E78.0 Pure hypercholesterolaemia	0.648	0.352
M47.87 Other spondylosis (Lumbosacral region)	0.648	0.352
J37 Chronic laryngitis and laryngotracheitis	0.647	0.353
M54.55 Low back pain (Thoracolumbar region)	0.647	0.353
M54.54 Low back pain-Thoracic	0.647	0.353
M54.53 Low back pain-Cervicothoracic	0.647	0.353
M54.52 Low back pain-Cervical	0.647	0.353
M54.51 Low back pain-Occipit-atl-axl	0.647	0.353
M54.50 Low back pain (Multiple sites in spine)	0.647	0.353
S49 Other and unspecified injuries of shoulder and upper arm	0.646	0.354
T93 Sequelae of injuries of lower limb	0.646	0.354
H35.8 Other specified retinal disorders	0.646	0.354
M41 Scoliosis	0.646	0.354
Z91 Personal history of risk-factors, not elsewhere classified	0.645	0.355
K50.1 Crohn's disease of large intestine	0.645	0.355
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.645	0.355
T90.2 Sequelae of fracture of skull and facial bones	0.645	0.355
J44 Other chronic obstructive pulmonary disease	0.645	0.355
I49.5 Sick sinus syndrome	0.643	0.357
R00.0 Tachycardia, unspecified	0.643	0.357
E05.9 Thyrotoxicosis, unspecified	0.643	0.357
I42.8 Other cardiomyopathies	0.642	0.357
I42.7 Cardiomyopathy due to drugs and other external agents	0.642	0.357
I42.6 Alcoholic cardiomyopathy	0.642	0.357
I42.5 Other restrictive cardiomyopathy	0.642	0.357
I42.4 Endocardial fibroelastosis	0.642	0.357
I42.3 Endomyocardial (eosinophilic) disease	0.642	0.357
I42.1 Obstructive hypertrophic cardiomyopathy	0.642	0.357
I23 Certain current complications following acute myocardial infarction	0.642	0.358
N32.3 Diverticulum of bladder	0.642	0.358
I20.0 Unstable angina	0.642	0.358
Z87 Personal history of other diseases and conditions	0.640	0.360
J34.2 Deviated nasal septum	0.640	0.360
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.640	0.360
H43.8 Other disorders of vitreous body	0.639	0.361
R04 Haemorrhage from respiratory passages	0.639	0.361
I84.9 Unspecified haemorrhoids without complication	0.638	0.362
G90-G99 Other disorders of the nervous system	0.638	0.362
M31 Other necrotising vasculopathies	0.637	0.363
A04.7 Enterocolitis due to Clostridium difficile	0.637	0.363
N02 Recurrent and persistent haematuria	0.637	0.363
D63.8 Anaemia in other chronic diseases classified elsewhere	0.635	0.364
R70-R79 Abnormal findings on examination of blood, without diagnosis	0.635	0.365
M50.2 Other cervical disk displacement	0.635	0.365
L40-L45 Papulosquamous disorders	0.634	0.366

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations