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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs11023139
log Bayes Factor = 9.7229
Chromosome 11   position 14,224,346  (GRCh37) Explore rs11023139 on Ensembl!
Variant rs11023139 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
M54 Dorsalgia
1.000 0.000 0.000
M50-M54 Other dorsopathies
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
M80-M85 Disorders of bone density and structure
0.999 0.001 0.000
Chapter XXI Factors influencing health status and contact with health services
0.999 0.001 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.998 0.002 0.000
M81 Osteoporosis without pathological fracture
0.998 0.002 0.000
M81.9 Osteoporosis, unspecified
0.997 0.003 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.996 0.004 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.995 0.005 0.000
M54.5 Low back pain
0.993 0.007 0.000
Z92 Personal history of medical treatment
0.993 0.007 0.000
Z42 Follow-up care involving plastic surgery
0.993 0.007 0.000
N20-N23 Urolithiasis
0.991 0.009 0.000
Z92.3 Personal history of irradiation
0.991 0.009 0.000
Z85.3 Personal history of malignant neoplasm of breast
0.991 0.009 0.000
Chapter XIV Diseases of the genitourinary system
0.991 0.009 0.000
M54.59 Low back pain (Site unspecified)
0.990 0.010 0.000
M81.99 Osteoporosis, unspecified (Site unspecified)
0.989 0.011 0.000
N20 Calculus of kidney and ureter
0.988 0.012 0.000
Z42.1 Follow-up care involving plastic surgery of breast
0.988 0.012 0.000
M05-M14 Inflammatory polyarthropathies
0.987 0.013 0.000
Z85 Personal history of malignant neoplasm
0.984 0.016 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.983 0.017 0.000
S20-S29 Injuries to the thorax
0.983 0.017 0.000
Z41 Procedures for purposes other than remedying health state
0.982 0.018 0.000
N23 Unspecified renal colic
0.975 0.025 0.000
Z41.1 Other plastic surgery for unacceptable cosmetic appearance
0.973 0.027 0.000
N20.1 Calculus of ureter
0.972 0.028 0.000
M81.90 Osteoporosis, unspecified (Multiple sites)
0.969 0.031 0.000
M54.3 Sciatica
0.968 0.032 0.000
M65-M68 Disorders of synovium and tendon
0.965 0.035 0.000
M54.9 Dorsalgia, unspecified
0.964 0.036 0.000
M86-M90 Other osteopathies
0.963 0.037 0.000
M06 Other rheumatoid arthritis
0.958 0.042 0.000
Chapter XX External causes of morbidity and mortality
0.957 0.043 0.000
M65 Synovitis and tenosynovitis
0.943 0.057 0.000
M51 Other intervertebral disk disorders
0.941 0.059 0.000
Z95.8 Presence of other cardiac and vascular implants and grafts
0.940 0.060 0.000
S50-S59 Injuries to the elbow and forearm
0.937 0.063 0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.930 0.070 0.000
M54.39 Sciatica (Site unspecified)
0.929 0.071 0.000
Z92.8 Personal history of other medical treatment
0.928 0.072 0.000
Z95.2 Presence of prosthetic heart valve
0.927 0.073 0.000
Z42.0 Follow-up care involving plastic surgery of head and neck
0.927 0.073 0.000
M54.99 Dorsalgia, unspecified (Site unspecified)
0.920 0.080 0.000
S90-S99 Injuries to the ankle and foot
0.918 0.082 0.000
Z92.0 Personal history of contraception
0.917 0.083 0.000
M06.9 Rheumatoid arthritis, unspecified
0.916 0.084 0.000
N25-N29 Other disorders of kidney and ureter
0.913 0.087 0.000
N10-N16 Renal tubulo-interstitial diseases
0.910 0.090 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.905 0.095 0.000
S40-S49 Injuries to the shoulder and upper arm
0.901 0.099 0.000
Z52 Donors of organs and tissues
0.898 0.102 0.000
M70-M79 Other soft tissue disorders
0.892 0.108 0.000
S20 Superficial injury of thorax
0.883 0.117 0.000
Z94 Transplanted organ and tissue status
0.881 0.118 0.000
M51.2 Other specified intervertebral disk displacement
0.879 0.121 0.000
M14 Arthropathies in other diseases classified elsewhere
0.877 0.123 0.000
N20.2 Calculus of kidney with calculus of ureter
0.875 0.125 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.873 0.127 0.000
M89 Other disorders of bone
0.871 0.129 0.000
M72 Fibroblastic disorders
0.869 0.131 0.000
M87 Osteonecrosis
0.868 0.132 0.000
N28 Other disorders of kidney and ureter, not elsewhere classified
0.865 0.135 0.000
Z83 Family history of other specific disorders
0.862 0.138 0.000
X20-X29 Contact with venomous animals and plants
0.860 0.140 0.000
Chapter II Neoplasms
0.859 0.141 0.000
N20.9 Urinary calculus, unspecified
0.859 0.141 0.000
V20-V29 Motorcycle rider injured in transport accident
0.856 0.144 0.000
M85 Other disorders of bone density and structure
0.853 0.147 0.000
M72.0 Palmar fascial fibromatosis [Dupuytren]
0.852 0.147 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.850 0.150 0.000
M84 Disorders of continuity of bone
0.850 0.150 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.850 0.150 0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)
0.848 0.152 0.000
M65.3 Trigger finger
0.846 0.154 0.000
M54.4 Lumbago with sciatica
0.844 0.156 0.000
M07 Psoriatic and enteropathic arthropathies
0.844 0.156 0.000
C79 Secondary malignant neoplasm of other sites
0.843 0.157 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.842 0.158 0.000
M06.3 Rheumatoid nodule
0.841 0.159 0.000
M72.04 Palmar fascial fibromatosis [Dupuytren]-Hand
0.841 0.159 0.000
S27 Injury of other and unspecified intrathoracic organs
0.840 0.160 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.840 0.160 0.000
M40-M43 Deforming dorsopathies
0.835 0.165 0.000
N28.1 Cyst of kidney, acquired
0.835 0.165 0.000
S50 Superficial injury of forearm
0.832 0.168 0.000
M05 Seropositive rheumatoid arthritis
0.831 0.169 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.830 0.170 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.829 0.171 0.000
S22.2 Fracture of sternum
0.828 0.172 0.000
V40-V49 Car occupant injured in transport accident
0.827 0.173 0.000
M65.8 Other synovitis and tenosynovitis
0.826 0.174 0.000
S42 Fracture of shoulder and upper arm
0.825 0.175 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.824 0.176 0.000
Z89 Acquired absence of limb
0.817 0.183 0.000
M54.8 Other dorsalgia
0.815 0.185 0.000
M54.36 Sciatica (Lumbar region)
0.814 0.186 0.000
W50-W64 Exposure to animate mechanical forces
0.813 0.186 0.000
C71 Malignant neoplasm of brain
0.813 0.187 0.000
M65.9 Synovitis and tenosynovitis, unspecified
0.810 0.190 0.000
M54.96 Dorsalgia, unspecified (Lumbar region)
0.808 0.192 0.000
T00-T07 Injuries involving multiple body regions
0.808 0.192 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.805 0.195 0.000
W00-W19 Falls
0.802 0.198 0.000
S20.8 Superficial injuries of other and unspecified parts of thorax
0.800 0.200 0.000
M87.9 Osteonecrosis, unspecified
0.799 0.201 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.798 0.202 0.000
S29 Other and unspecified injuries of thorax
0.798 0.202 0.000
M14.6 Neuropathic arthropathy
0.798 0.202 0.000
M91-M94 Chondropathies
0.797 0.203 0.000
M51.8 Other specified intervertebral disk disorders
0.796 0.204 0.000
N17-N19 Renal failure
0.795 0.205 0.000
Z83.5 Family history of eye and ear disorders
0.794 0.206 0.000
S10-S19 Injuries to the neck
0.792 0.208 0.000
Chapter VIII Diseases of the ear and mastoid process
0.792 0.208 0.000
X23 Contact with hornets, wasps and bees
0.790 0.210 0.000
C50-C50 Malignant neoplasm of breast
0.789 0.211 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.787 0.213 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.786 0.214 0.000
N20.0 Calculus of kidney
0.785 0.215 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.783 0.217 0.000
S51 Open wound of forearm
0.778 0.222 0.000
M65.34 Trigger finger-Hand
0.777 0.223 0.000
Z94.7 Corneal transplant status
0.777 0.223 0.000
Z53 Persons encountering health services for specifie procedures, not carried out
0.773 0.227 0.000
S22.20 Fracture of sternum (closed)
0.772 0.228 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.769 0.231 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.769 0.231 0.000
M54.97 Dorsalgia, unspecified (Lumbosacral region)
0.768 0.231 0.000
M89.8 Other specified disorders of bone
0.767 0.233 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.767 0.233 0.000
Z52.3 Bone marrow donor
0.766 0.234 0.000
N11 Chronic tubulo-interstitial nephritis
0.766 0.234 0.000
M85.6 Other cyst of bone
0.763 0.237 0.000
M60-M63 Disorders of muscles
0.763 0.237 0.000
N13 Obstructive and reflux uropathy
0.761 0.239 0.000
V23 Motorcycle rider injured in collision with car, pick-up truck or van
0.758 0.242 0.000
T63 Toxic effect of contact with venomous animals
0.758 0.242 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.758 0.242 0.000
M54.1 Radiculopathy
0.757 0.243 0.000
S50.9 Superficial injury of forearm, unspecified
0.757 0.243 0.000
S92 Fracture of foot, except ankle
0.755 0.245 0.000
W20-W49 Exposure to inanimate mechanical forces
0.755 0.245 0.000
M86 Osteomyelitis
0.754 0.246 0.000
M54.57 Low back pain (Lumbosacral region)
0.751 0.249 0.000
Z91.5 Personal history of self-harm
0.751 0.249 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.749 0.251 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.747 0.253 0.000
Z95.4 Presence of other heart-valve replacement
0.747 0.253 0.000
M65.4 Radial styloid tenosynovitis [de Quervain]
0.745 0.255 0.000
S22.4 Multiple fractures of ribs
0.745 0.255 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.743 0.257 0.000
N10 Acute tubulo-interstitial nephritis
0.743 0.257 0.000
M07.3 Other psoriatic arthropathies
0.741 0.259 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.739 0.261 0.000
E65-E68 Obesity and other hyperalimentation
0.739 0.261 0.000
M88 Paget's disease of bone [osteitis deformans]
0.739 0.261 0.000
C50 Malignant neoplasm of breast
0.739 0.261 0.000
Z52.4 Kidney donor
0.739 0.261 0.000
Z97 Presence of other devices
0.737 0.263 0.000
Z42.4 Follow-up care involving plastic surgery of lower extremity
0.737 0.263 0.000
M65.86 Other synovitis and tenosynovitis (Lower leg)
0.737 0.263 0.000
S42.2 Fracture of upper end of humerus
0.735 0.265 0.000
S90 Superficial injury of ankle and foot
0.734 0.266 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.733 0.267 0.000
M54.6 Pain in thoracic spine
0.731 0.269 0.000
V48 Car occupant injured in noncollision transport accident
0.727 0.273 0.000
M81.4 Drug-induced osteoporosis
0.726 0.274 0.000
S52 Fracture of forearm
0.726 0.274 0.000
Z94.8 Other transplanted organ and tissue status
0.726 0.274 0.000
T79-T79 Certain early complications of trauma
0.725 0.275 0.000
M87.95 Osteonecrosis, unspecified (Pelvic region and thigh)
0.725 0.275 0.000
S27.2 Traumatic heamopneumothorax
0.725 0.275 0.000
X23.9 Unspecified place
0.724 0.276 0.000
M51.0 Lumbar and other intervertebral disk disorders with myelopathy
0.723 0.277 0.000
M45-M49 Spondylopathies
0.723 0.277 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.722 0.278 0.000
M54.47 Lumbago with sciatica (Lumbosacral region)
0.722 0.278 0.000
M54.50 Low back pain (Multiple sites in spine)
0.722 0.278 0.000
Z95.3 Presence of xenogenic heart valve
0.721 0.279 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.719 0.281 0.000
C71.1 Frontal lobe
0.719 0.281 0.000
Z53.0 Procedure not carried out because of contraindication
0.718 0.282 0.000
M81.98 Osteoporosis, unspecified (Other)
0.718 0.282 0.000
S59 Other and unspecified injuries of forearm
0.718 0.282 0.000
E66 Obesity
0.718 0.282 0.000
M54.0 Panniculitis affecting regions of neck and back
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
M83 Adult osteomalacia
0.716 0.283 0.000
N00-N08 Glomerular diseases
0.716 0.284 0.000
M81.8 Other osteoporosis
0.715 0.285 0.000
M81.6 Localised osteoporosis [Lequesne]
0.715 0.285 0.000
M81.5 Idiopathic osteoporosis
0.715 0.285 0.000
M81.3 Postsurgical malabsorption osteoporosis
0.715 0.285 0.000
M81.2 Osteoporosis of disuse
0.715 0.285 0.000
M81.1 Postoophorectomy osteoporosis
0.715 0.285 0.000
M81.0 Postmenopausal osteoporosis
0.715 0.285 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.715 0.285 0.000
M81.97 Osteoporosis, unspecified (Ankle and foot)
0.715 0.285 0.000
M81.96 Osteoporosis, unspecified (Lower leg)
0.715 0.285 0.000
M81.94 Osteoporosis, unspecified (Hand)
0.715 0.285 0.000
M81.93 Osteoporosis, unspecified (Forearm)
0.715 0.285 0.000
M81.92 Osteoporosis, unspecified (Upper arm)
0.715 0.285 0.000
M81.91 Osteoporosis, unspecified (Shoulder region)
0.715 0.285 0.000
T33-T35 Frostbite
0.714 0.286 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.714 0.286 0.000
Z44 Fitting and adjustment of external prosthetic device
0.713 0.286 0.000
M54.55 Low back pain (Thoracolumbar region)
0.712 0.288 0.000
M54.54 Low back pain-Thoracic
0.712 0.288 0.000
M54.53 Low back pain-Cervicothoracic
0.712 0.288 0.000
M54.52 Low back pain-Cervical
0.712 0.288 0.000
M54.51 Low back pain-Occipit-atl-axl
0.712 0.288 0.000
Z92.9 Personal history of medical treatment, unspecified
0.712 0.288 0.000
Z92.5 Personal history of rehabilitation measures
0.712 0.288 0.000
Z42.9 Follow-up care involving plastic surgery, unspecified
0.712 0.288 0.000
Z42.8 Follow-up care involving plastic surgery of other body part
0.712 0.288 0.000
Z40 Prophylactic surgery
0.712 0.288 0.000
Z91.0 Personal history of allergy, other than to drugs and biological substances
0.712 0.288 0.000
M06.37 Rheumatoid nodule (Ankle and foot)
0.711 0.289 0.000
N22 Calculus of urinary tract in diseases classified elsewhere
0.711 0.289 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.710 0.290 0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand
0.710 0.290 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.709 0.291 0.000
Q80-Q89 Other congenital malformations
0.709 0.291 0.000
M00-M03 Infectious arthropathies
0.709 0.291 0.000
C50.8 Overlapping lesion of breast
0.708 0.292 0.000
M12 Other specific arthropathies
0.708 0.292 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.708 0.292 0.000
M08 Juvenile arthritis
0.708 0.292 0.000
X50-X57 Overexertion, travel and privation
0.707 0.293 0.000
Z85.0 Personal history of malignant neoplasm of digestive organs
0.706 0.294 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.706 0.294 0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax
0.705 0.295 0.000
S26 Injury of heart
0.705 0.295 0.000
S25 Injury of blood vessels of thorax
0.705 0.295 0.000
S24 Injury of nerves and spinal cord at thorax level
0.705 0.295 0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax
0.705 0.295 0.000
S21 Open wound of thorax
0.705 0.295 0.000
Z41.9 Procedures for purposes other than remedying health state, unspecified
0.704 0.296 0.000
Z41.8 Other procedures for purposes other than remedying health state
0.704 0.296 0.000
Z41.3 Ear piercing
0.704 0.296 0.000
Z41.2 Routine and ritual circumcision
0.704 0.296 0.000
Z41.0 Hair transplant
0.704 0.296 0.000
E66.8 Other obesity
0.703 0.297 0.000
W55 Bitten or struck by other mammals
0.703 0.297 0.000
M54.98 Dorsalgia, unspecified (Sacral and sacrococcygeal region)
0.702 0.298 0.000
S99 Other and unspecified injuries of ankle and foot
0.700 0.300 0.000
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)
0.700 0.300 0.000
W06 Fall involving bed
0.700 0.300 0.000
M85.65 Other cyst of bone (Pelvic region and thigh)
0.699 0.301 0.000
T66-T78 Other and unspecified effects of external causes
0.698 0.302 0.000
Z81 Family history of mental and behavioural disorders
0.698 0.302 0.000
M11 Other crystal arthropathies
0.698 0.302 0.000
M53 Other dorsopathies, not elsewhere classified
0.697 0.302 0.000
M82 Osteoporosis in diseases classified elsewhere
0.697 0.303 0.000
M84.4 Pathological fracture, not elsewhere classified
0.696 0.304 0.000
Z53.8 Procedure not carried out for other reasons
0.696 0.304 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.695 0.305 0.000
Z85.6 Personal history of leukaemia
0.695 0.305 0.000
Z89.4 Acquired absence of foot and ankle
0.694 0.306 0.000
M54.38 Sciatica (Sacral and sacrococcygeal region)
0.694 0.306 0.000
M54.35 Sciatica (Thoracolumbar region)
0.694 0.306 0.000
M54.34 Sciatica-Thoracic
0.694 0.306 0.000
M54.33 Sciatica-Cervicothoracic
0.694 0.306 0.000
M54.32 Sciatica-Cervical
0.694 0.306 0.000
M54.31 Sciatica-Occipit-atl-axl
0.694 0.306 0.000
M54.30 Sciatica (Multiple sites in spine)
0.694 0.306 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.694 0.306 0.000
T63.4 Venom of other arthropods
0.693 0.307 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.692 0.308 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.692 0.308 0.000
M54.95 Dorsalgia, unspecified (Thoracolumbar region)
0.691 0.309 0.000
M54.93 Dorsalgia, unspecified (Cervicothoracic region)
0.691 0.309 0.000
M54.92 Dorsalgia, unspecified (Cervical region)
0.691 0.309 0.000
M54.91 Dorsalgia, unspecified (Occipito-atlanto-axial region)
0.691 0.309 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.691 0.309 0.000
V23.4 Driver injured in traffic accident
0.688 0.312 0.000
M06.34 Rheumatoid nodule (Hand)
0.688 0.312 0.000
Z80 Family history of malignant neoplasm
0.688 0.312 0.000
M06.8 Other specified rheumatoid arthritis
0.687 0.313 0.000
M06.2 Rheumatoid bursitis
0.687 0.313 0.000
M06.1 Adult-onset Still's disease
0.687 0.313 0.000
Y35-Y36 Legal intervention and operations of war
0.686 0.314 0.000
Y10-Y34 Event of undetermined intent
0.686 0.314 0.000
Y00-Y09 Assault
0.686 0.314 0.000
X85-X99 Assault
0.686 0.314 0.000
X30-X39 Exposure to forces of nature
0.686 0.314 0.000
X10-X19 Contact with heat and hot substances
0.686 0.314 0.000
X00-X09 Exposure to smoke, fire and flames
0.686 0.314 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.686 0.314 0.000
W75-W84 Other accidental threats to breathing
0.686 0.314 0.000
W65-W74 Accidental drowning and submersion
0.686 0.314 0.000
V98-V99 Other and unspecified transport accidents
0.686 0.314 0.000
V95-V97 Air and space transport accidents
0.686 0.314 0.000
V90-V94 Water transport accidents
0.686 0.314 0.000
V70-V79 Bus occupant injured in transport accident
0.686 0.314 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.686 0.314 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.686 0.314 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.686 0.314 0.000
V01-V09 Pedestrian injured in transport accident
0.686 0.314 0.000
D69 Purpura and other haemorrhagic conditions
0.686 0.314 0.000
Z52.0 Blood donor
0.686 0.314 0.000
M54.37 Sciatica (Lumbosacral region)
0.685 0.315 0.000
M67 Other disorders of synovium and tendon
0.685 0.315 0.000
C71.9 Brain, unspecified
0.685 0.315 0.000
S51.0 Open wound of elbow
0.684 0.316 0.000
S20.3 Other superficial injuries of front wall of thorax
0.684 0.316 0.000
N19 Unspecified renal failure
0.683 0.317 0.000
M65.91 Synovitis and tenosynovitis, unspecified (Shoulder region)
0.683 0.317 0.000
C71.2 Temporal lobe
0.683 0.317 0.000
M54.89 Other dorsalgia (Site unspecified)
0.683 0.317 0.000
M80 Osteoporosis with pathological fracture
0.682 0.318 0.000
M65.92 Synovitis and tenosynovitis, unspecified (Upper arm)
0.682 0.318 0.000
M43 Other deforming dorsopathies
0.681 0.319 0.000
C80 Malignant neoplasm without specification of site
0.681 0.319 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.681 0.319 0.000
M65.1 Other infective (teno)synovitis
0.680 0.320 0.000
M89.9 Disorder of bone, unspecified
0.680 0.320 0.000
S22.1 Multiple fractures of thoracic spine
0.679 0.320 0.000
Z94.1 Heart transplant status
0.679 0.321 0.000
S27.3 Other injuries of lung
0.678 0.322 0.000
M65.2 Calcific tendinitis
0.676 0.324 0.000
M65.0 Abscess of tendon sheath
0.676 0.324 0.000
V28 Motorcycle rider injured in noncollision transport accident
0.676 0.324 0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards
0.676 0.324 0.000
M54.90 Dorsalgia, unspecified (Multiple sites in spine)
0.675 0.325 0.000
M51.3 Other specified intervertebral disk degeneration
0.674 0.325 0.000
M51.1 Lumbar and other intervertebral disk disorders with radiculopathy
0.674 0.325 0.000
M51.4 Schmorl's nodes
0.674 0.325 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.673 0.327 0.000
T00 Superficial injuries involving multiple body regions
0.673 0.327 0.000
W18 Other fall on same level
0.673 0.327 0.000
S80-S89 Injuries to the knee and lower leg
0.672 0.328 0.000
S58 Traumatic amputation of forearm
0.672 0.328 0.000
S57 Crushing injury of forearm
0.672 0.328 0.000
S55 Injury of blood vessels at forearm level
0.672 0.328 0.000
S54 Injury of nerves at forearm level
0.672 0.328 0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow
0.672 0.328 0.000
Z91.1 Personal history of noncompliance with medical treatment and regimen
0.671 0.328 0.000
S42.20 Fracture of upper end of humerus (closed)
0.670 0.330 0.000
S56 Injury of muscle and tendon at forearm level
0.670 0.330 0.000
M54.46 Lumbago with sciatica (Lumbar region)
0.670 0.330 0.000
M89.3 Hypertrophy of bone
0.669 0.331 0.000
D69.6 Thrombocytopenia, unspecified
0.669 0.331 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.668 0.331 0.000
V80-V89 Other land transport accidents
0.667 0.333 0.000
Z85.2 Personal history of malignant neoplasm of other respiratory and intrathoracic organs
0.667 0.333 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.667 0.333 0.000
M06.4 Inflammatory polyarthropathy
0.666 0.333 0.000
H60-H62 Diseases of external ear
0.666 0.334 0.000
Z42.2 Follow-up care involving plastic surgery of other parts of trunk
0.666 0.334 0.000
S29.9 Unspecified injury of thorax
0.666 0.334 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.665 0.335 0.000
M06.0 Seronegative rheumatoid arthritis
0.665 0.335 0.000
M66 Spontaneous rupture of synovium and tendon
0.664 0.336 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.664 0.336 0.000
Z46 Fitting and adjustment of other devices
0.663 0.337 0.000
N11.9 Chronic tubulo-interstitial nephritis, unspecified
0.663 0.337 0.000
M77 Other enthesopathies
0.662 0.338 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.662 0.338 0.000
S22.5 Flail chest
0.661 0.339 0.000
S40 Superficial injury of shoulder and upper arm
0.660 0.340 0.000
C71.0 Cerebrum, except lobes and ventricles
0.660 0.340 0.000
N99-N99 Other disorders of the genitourinary system
0.659 0.341 0.000
S91 Open wound of ankle and foot
0.659 0.341 0.000
S98 Traumatic amputation of ankle and foot
0.658 0.342 0.000
S97 Crushing injury of ankle and foot
0.658 0.342 0.000
S96 Injury of muscle and tendon at ankle and foot level
0.658 0.342 0.000
S95 Injury of blood vessels at ankle and foot level
0.658 0.342 0.000
S94 Injury of nerves at ankle and foot level
0.658 0.342 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.657 0.343 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.657 0.343 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.656 0.344 0.000
V48.4 Person injured while boarding or alighting
0.655 0.345 0.000
N29 Other disorders of kidney and ureter in diseases classified elsewhere
0.655 0.345 0.000
N27 Small kidney of unknown cause
0.655 0.345 0.000
N25 Disorders resulting from impaired renal tubular function
0.655 0.345 0.000
M84.0 Malunion of fracture
0.654 0.346 0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere
0.652 0.348 0.000
N15 Other renal tubulo-interstitial diseases
0.652 0.348 0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
0.652 0.348 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.652 0.348 0.000
Z80.4 Family history of malignant neoplasm of genital organs
0.651 0.349 0.000
S22.9 Fracture of bony thorax, part unspecified
0.649 0.351 0.000
S22.8 Fracture of other parts of bony thorax
0.649 0.351 0.000
N13.3 Other and unspecified hydronephrosis
0.648 0.352 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.647 0.352 0.000
M87.97 Osteonecrosis, unspecified (Ankle and foot)
0.646 0.354 0.000
M93 Other osteochondropathies
0.646 0.354 0.000
N18 Chronic renal failure
0.646 0.354 0.000
S48 Traumatic amputation of shoulder and upper arm
0.646 0.354 0.000
S45 Injury of blood vessels at shoulder and upper arm level
0.646 0.354 0.000
S44 Injury of nerves at shoulder and upper arm level
0.646 0.354 0.000
S47 Crushing injury of shoulder and upper arm
0.646 0.354 0.000
Z82.3 Family history of stroke
0.646 0.354 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.644 0.356 0.000
Z52.9 Donor of unspecified organ or tissue
0.644 0.356 0.000
Z52.8 Donor of other organs and tissues
0.644 0.356 0.000
Z52.7 Heart donor
0.644 0.356 0.000
Z52.6 Liver donor
0.644 0.356 0.000
Z52.5 Cornea donor
0.644 0.356 0.000
Z52.2 Bone donor
0.644 0.356 0.000
Z52.1 Skin donor
0.644 0.356 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.644 0.356 0.000
Z94.4 Liver transplant status
0.643 0.357 0.000
M41 Scoliosis
0.642 0.358 0.000
S27.20 Traumatic haemopneumothorax (without open wound into thoracic cavity)
0.642 0.358 0.000
S12 Fracture of neck
0.641 0.358 0.000
Y45.1 Salicylates
0.640 0.360 0.000
N28.0 Ischaemia and infarction of kidney
0.640 0.360 0.000
M76 Enthesopathies of lower limb, excluding foot
0.639 0.361 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.639 0.361 0.000
S42.7 Multiple fractures of clavicle, scapula and humerus
0.639 0.361 0.000
Z84 Family history of other conditions
0.637 0.363 0.000
T23 Burn and corrosion of wrist and hand
0.637 0.363 0.000
M65.95 Synovitis and tenosynovitis, unspecified (Pelvic region and thigh)
0.637 0.363 0.000
S41 Open wound of shoulder and upper arm
0.636 0.364 0.000
M72.2 Plantar fascial fibromatosis
0.635 0.365 0.000
Z54 Convalescence
0.635 0.365 0.000
Z83.3 Family history of diabetes mellitus
0.634 0.366 0.000
S42.0 Fracture of clavicle
0.634 0.366 0.000
Q00-Q07 Congenital malformations of the nervous system
0.633 0.366 0.000
S93.1 Dislocation of toe(s)
0.633 0.367 0.000
S20.7 Multiple superficial injuries of thorax
0.633 0.367 0.000
S20.4 Other superficial injuries of back wall of thorax
0.633 0.367 0.000
S20.1 Other and unspecified superficial injuries of breast
0.633 0.367 0.000
S20.0 Contusion of breast
0.633 0.367 0.000
M89.86 Other specified disorders of bone (Lower leg)
0.633 0.367 0.000
C71.8 Overlapping lesion of brain
0.632 0.368 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.632 0.368 0.000
Z94.9 Transplanted organ and tissue status, unspecified
0.632 0.368 0.000
Z94.6 Bone transplant status
0.632 0.368 0.000
Z94.5 Skin transplant status
0.632 0.368 0.000
Z94.3 Heart and lungs transplant status
0.632 0.368 0.000
Z94.2 Lung transplant status
0.632 0.368 0.000
T17 Foreign body in respiratory tract
0.632 0.368 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.631 0.369 0.000
N28.9 Disorder of kidney and ureter, unspecified
0.631 0.369 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.631 0.369 0.000
S43.1 Dislocation of acromioclavicular joint
0.631 0.369 0.000
S22.40 Multiple fractures of ribs (closed)
0.631 0.369 0.000
N13.4 Hydroureter
0.629 0.371 0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.629 0.371 0.000
W17 Other fall from one level to another
0.629 0.371 0.000
C71.3 Parietal lobe
0.629 0.371 0.000
M14.8 Arthropathies in other specified diseases classified elsewhere
0.629 0.371 0.000
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders
0.629 0.371 0.000
M14.4 Arthropathy in amyloidosis
0.629 0.371 0.000
M14.3 Lipoid dermatoarthritis
0.629 0.371 0.000
M14.2 Diabetic arthropathy
0.629 0.371 0.000
M14.1 Crystal arthropathy in other metabolic disorders
0.629 0.371 0.000
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders
0.629 0.371 0.000
M87.2 Osteonecrosis due to previous trauma
0.628 0.372 0.000
M89.85 Other specified disorders of bone (Pelvic region and thigh)
0.628 0.372 0.000
C34 Malignant neoplasm of bronchus and lung
0.628 0.372 0.000
W06.0 Home
0.627 0.373 0.000
N13.6 Pyonephrosis
0.626 0.374 0.000
Z91.8 Personal history of other specified risk-factors, not elsewhere classified
0.626 0.374 0.000
Z91.7 Personal history of female genital mutilation
0.626 0.374 0.000
Z91.4 Personal history of psychological trauma, not elsewhere classified
0.626 0.374 0.000
Z91.3 Personal history of unhealthy sleep-wake schedule
0.626 0.374 0.000
Z91.2 Personal history of poor personal hygiene
0.626 0.374 0.000
W22 Striking against or struck by other objects
0.626 0.374 0.000
D55-D59 Haemolytic anaemias
0.625 0.375 0.000
Z49 Care involving dialysis
0.625 0.375 0.000
Z92.4 Personal history of major surgery, not elsewhere classified
0.625 0.375 0.000
M89.6 Osteopathy after poliomyelitis
0.624 0.375 0.000
M89.5 Osteolysis
0.624 0.375 0.000
M89.4 Other hypertrophic osteo-arthropathy
0.624 0.375 0.000
M89.2 Other disorders of bone development and growth
0.624 0.375 0.000
M89.1 Epiphyseal arrest
0.624 0.375 0.000
M89.0 Algoneurodystrophy
0.624 0.375 0.000
M72.9 Fibroblastic disorder, unspecified
0.623 0.377 0.000
M72.8 Other fibroblastic disorders
0.623 0.377 0.000
M72.6 Necrotizing fasciitis
0.623 0.377 0.000
M72.5 Fasciitis, not elsewhere classified
0.623 0.377 0.000
M72.4 Pseudosarcomatous fibromatosis
0.623 0.377 0.000
M72.3 Nodular fasciitis
0.623 0.377 0.000
M72.1 Knuckle pads
0.623 0.377 0.000
S42.1 Fracture of scapula
0.623 0.377 0.000
S42.3 Fracture of shaft of humerus
0.623 0.377 0.000
M87.8 Other osteonecrosis
0.623 0.377 0.000
M87.3 Other secondary osteonecrosis
0.623 0.377 0.000
M87.1 Osteonecrosis due to drugs
0.623 0.377 0.000
M87.0 Idiopathic aseptic necrosis of bone
0.623 0.377 0.000
Z85.9 Personal history of malignant neoplasm, unspecified
0.622 0.378 0.000
Z42.3 Follow-up care involving plastic surgery of upper extremity
0.621 0.378 0.000
C50.9 Breast, unspecified
0.622 0.378 0.000
X23.0 Home
0.621 0.379 0.000
Z82.6 Family history of arthritis and other diseases of the musculoskeletal system and connective tissue
0.621 0.379 0.000
Q50-Q56 Congenital malformations of genital organs
0.621 0.379 0.000
M46 Other inflammatory spondylopathies
0.621 0.379 0.000
C79.6 Secondary malignant neoplasm of ovary
0.619 0.381 0.000
Z83.6 Family history of diseases of the respiratory system
0.618 0.382 0.000
Z83.2 Family history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.618 0.382 0.000
Z83.1 Family history of other infectious and parasitic diseases
0.618 0.382 0.000
Z83.0 Family history of human immunodeficiency virus [HIV]
0.618 0.382 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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