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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs111751241
log Bayes Factor = 9.57727
Chromosome 1   position 183,349,952  (GRCh37) Explore rs111751241 on Ensembl!
Variant rs111751241 is part of Cluster X0138

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
1.000 0.000 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
C44 Other malignant neoplasms of skin
0.999 0.001 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.999 0.001 0.000
C15-C26 Malignant neoplasms of digestive organs
0.997 0.003 0.000
Z88.8 Personal history of allergy to other drugs, medicaments and biological substances
0.995 0.005 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.995 0.005 0.000
T81 Complications of procedures, not elsewhere classified
0.994 0.006 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.990 0.010 0.000
Z91.0 Personal history of allergy, other than to drugs and biological substances
0.988 0.012 0.000
T81.3 Disruption of operation wound, not elsewhere classified
0.982 0.018 0.000
Z88.5 Personal history of allergy to narcotic agent
0.982 0.018 0.000
C44.6 Skin of upper limb, including shoulder
0.978 0.022 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.978 0.022 0.000
Z93 Artificial opening status
0.970 0.030 0.000
C18 Malignant neoplasm of colon
0.970 0.030 0.000
Chapter XXII Codes for special purposes
0.970 0.030 0.000
M20-M25 Other joint disorders
0.968 0.032 0.000
M86-M90 Other osteopathies
0.962 0.038 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.962 0.038 0.000
Z98 Other postsurgical states
0.956 0.044 0.000
Z93.3 Colostomy status
0.956 0.044 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.954 0.046 0.000
M24 Other specific joint derangements
0.952 0.048 0.000
S40-S49 Injuries to the shoulder and upper arm
0.950 0.050 0.000
Z98.0 Intestinal bypass and anastomosis status
0.943 0.057 0.000
C44.5 Skin of trunk
0.942 0.058 0.000
Chapter VIII Diseases of the ear and mastoid process
0.942 0.058 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.941 0.059 0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified
0.940 0.060 0.000
M80-M85 Disorders of bone density and structure
0.939 0.061 0.000
Z90.4 Acquired absence of other parts of digestive tract
0.932 0.068 0.000
C44.0 Skin of lip
0.931 0.069 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.931 0.069 0.000
S42 Fracture of shoulder and upper arm
0.930 0.070 0.000
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified
0.930 0.070 0.000
Z88.0 Personal history of allergy to penicillin
0.929 0.071 0.000
D00-D09 In situ neoplasms
0.928 0.072 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.926 0.074 0.000
Z94 Transplanted organ and tissue status
0.926 0.074 0.000
Z71.3 Dietary counselling and surveillance
0.921 0.079 0.000
C20 Malignant neoplasm of rectum
0.919 0.081 0.000
C44.1 Skin of eyelid, including canthus
0.918 0.082 0.000
Z90.8 Acquired absence of other organs
0.918 0.082 0.000
M65-M68 Disorders of synovium and tendon
0.915 0.085 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.911 0.089 0.000
C44.4 Skin of scalp and neck
0.910 0.090 0.000
C21 Malignant neoplasm of anus and anal canal
0.908 0.092 0.000
M89 Other disorders of bone
0.906 0.094 0.000
C16 Malignant neoplasm of stomach
0.905 0.095 0.000
Z88.9 Personal history of allergy to unspecified drugs, medicaments and biological substances
0.900 0.100 0.000
Z88.6 Personal history of allergy to analgesic agent
0.898 0.102 0.000
H80-H83 Diseases of inner ear
0.896 0.104 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.891 0.109 0.000
U80 Agent resistant to penicillin and related antibiotics
0.891 0.109 0.000
Chapter VI Diseases of the nervous system
0.891 0.109 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.887 0.113 0.000
M23 Internal derangement of knee
0.884 0.116 0.000
S42.0 Fracture of clavicle
0.882 0.118 0.000
H83 Other diseases of inner ear
0.880 0.120 0.000
S32 Fracture of lumbar spine and pelvis
0.876 0.124 0.000
D06 Carcinoma in situ of cervix uteri
0.876 0.124 0.000
Z87 Personal history of other diseases and conditions
0.876 0.124 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.873 0.127 0.000
H83.0 Labyrinthitis
0.868 0.132 0.000
C18.9 Colon, unspecified
0.866 0.134 0.000
M45-M49 Spondylopathies
0.864 0.136 0.000
T18 Foreign body in alimentary tract
0.862 0.138 0.000
M80 Osteoporosis with pathological fracture
0.861 0.139 0.000
C43 Malignant melanoma of skin
0.860 0.140 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.855 0.145 0.000
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure
0.855 0.145 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.852 0.148 0.000
M24.8 Other specific joint derangements, not elsewhere classified
0.849 0.151 0.000
S42.00 Fracture of clavicle (closed)
0.847 0.153 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.844 0.156 0.000
S42.4 Fracture of lower end of humerus
0.844 0.156 0.000
M23.20 Derangement of meniscus due to old tear or injury (Multiple sites)
0.842 0.158 0.000
Z93.1 Gastrostomy status
0.842 0.158 0.000
Z87.2 Personal history of diseases of the skin and subcutaneous tissue
0.841 0.159 0.000
D06.9 Cervix, unspecified
0.839 0.161 0.000
S31 Open wound of abdomen, lower back and pelvis
0.839 0.161 0.000
Z87.1 Personal history of diseases of the digestive system
0.836 0.164 0.000
Z74 Problems related to care-provider dependency
0.834 0.166 0.000
Q00-Q07 Congenital malformations of the nervous system
0.832 0.168 0.000
M23.21 Derangement of meniscus due to old tear or injury (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.831 0.169 0.000
C21.0 Anus, unspecified
0.829 0.171 0.000
S90-S99 Injuries to the ankle and foot
0.828 0.172 0.000
C18.6 Descending colon
0.828 0.172 0.000
M24.1 Other articular cartilage disorders
0.828 0.172 0.000
G90-G99 Other disorders of the nervous system
0.827 0.173 0.000
C18.0 Caecum
0.826 0.174 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.826 0.174 0.000
Z71.8 Other specified counselling
0.820 0.180 0.000
Z94.4 Liver transplant status
0.820 0.180 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.818 0.181 0.000
T18.1 Foreign body in oesophagus
0.817 0.183 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.816 0.184 0.000
M84 Disorders of continuity of bone
0.815 0.185 0.000
M89.9 Disorder of bone, unspecified
0.815 0.185 0.000
Z94.1 Heart transplant status
0.813 0.187 0.000
T81.8 Other complications of procedures, not elsewhere classified
0.811 0.189 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.807 0.193 0.000
Z97 Presence of other devices
0.807 0.193 0.000
T14 Injury of unspecified body region
0.807 0.193 0.000
C43.5 Malignant melanoma of trunk
0.806 0.194 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.806 0.194 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.805 0.195 0.000
M21 Other acquired deformities of limbs
0.804 0.196 0.000
Chapter XX External causes of morbidity and mortality
0.801 0.199 0.000
U80.0 Penicillin resistant agent
0.800 0.200 0.000
T86 Failure and rejection of transplanted organs and tissues
0.800 0.200 0.000
H60-H62 Diseases of external ear
0.798 0.202 0.000
M66 Spontaneous rupture of synovium and tendon
0.794 0.206 0.000
G62 Other polyneuropathies
0.794 0.206 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.793 0.207 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.791 0.209 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.790 0.210 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.788 0.212 0.000
C16.9 Stomach, unspecified
0.787 0.213 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.786 0.214 0.000
Z93.9 Artificial opening status, unspecified
0.785 0.215 0.000
D04 Carcinoma in situ of skin
0.782 0.217 0.000
S42.40 Fracture of lower end of humerus (closed)
0.782 0.218 0.000
M90 Osteopathies in diseases classified elsewhere
0.781 0.219 0.000
C18.5 Splenic flexure
0.780 0.219 0.000
M87 Osteonecrosis
0.780 0.220 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.779 0.221 0.000
U80.1 Methicillin resistant agent
0.778 0.222 0.000
Q50-Q56 Congenital malformations of genital organs
0.777 0.223 0.000
Z71.4 Alcohol abuse counselling and surveillance
0.776 0.224 0.000
T81.1 Shock during or resulting from a procedure, not elsewhere classified
0.776 0.224 0.000
Z81 Family history of mental and behavioural disorders
0.776 0.224 0.000
Z76 Persons encountering health services in other circumstances
0.773 0.227 0.000
Z73 Problems related to life-management difficulty
0.771 0.229 0.000
M46 Other inflammatory spondylopathies
0.771 0.229 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.770 0.230 0.000
T87 Complications peculiar to reattachment and amputation
0.770 0.230 0.000
Z91.8 Personal history of other specified risk-factors, not elsewhere classified
0.769 0.231 0.000
S32.0 Fracture of lumbar vertebra
0.767 0.233 0.000
C16.5 Lesser curvature of stomach, unspecified
0.766 0.234 0.000
M24.2 Disorder of ligament
0.764 0.236 0.000
M22 Disorders of patella
0.763 0.237 0.000
M89.8 Other specified disorders of bone
0.762 0.238 0.000
M23.25 Derangement of meniscus due to old tear or injury (Posterior horn of lateral meniscus)
0.762 0.238 0.000
M24.0 Loose body in joint
0.761 0.239 0.000
S32.1 Fracture of sacrum
0.761 0.239 0.000
Z99.1 Dependence on respirator
0.761 0.239 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.759 0.241 0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.757 0.243 0.000
C18.1 Appendix
0.757 0.243 0.000
M40-M43 Deforming dorsopathies
0.757 0.243 0.000
G93 Other disorders of brain
0.755 0.245 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.752 0.247 0.000
S42.3 Fracture of shaft of humerus
0.751 0.249 0.000
Q23 Congenital malformations of aortic and mitral valves
0.750 0.250 0.000
T14.0 Superficial injury of unspecified body region
0.750 0.250 0.000
C18.2 Ascending colon
0.749 0.251 0.000
M65 Synovitis and tenosynovitis
0.747 0.253 0.000
G70-G73 Diseases of myoneural junction and muscle
0.747 0.253 0.000
Z88.4 Personal history of allergy to anaesthetic agent
0.744 0.256 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.744 0.256 0.000
M24.5 Contracture of joint
0.743 0.256 0.000
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified
0.743 0.257 0.000
U51 Admission status on psychiatric patients
0.743 0.257 0.000
M80.0 Postmenopausal osteoporosis with pathological fracture
0.742 0.258 0.000
H90-H95 Other disorders of ear
0.741 0.259 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.741 0.259 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.741 0.259 0.000
H60 Otitis externa
0.740 0.260 0.000
M60-M63 Disorders of muscles
0.739 0.261 0.000
G62.9 Polyneuropathy, unspecified
0.739 0.261 0.000
M24.85 Other specific joint derangements, not elsewhere classified (Pelvic region and thigh)
0.739 0.261 0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.737 0.263 0.000
C44.9 Malignant neoplasm of skin, unspecified
0.737 0.263 0.000
T16 Foreign body in ear
0.737 0.263 0.000
C64-C68 Malignant neoplasms of urinary tract
0.735 0.265 0.000
Z93.4 Other artificial openings of gastro-intestinal tract status
0.729 0.271 0.000
S10-S19 Injuries to the neck
0.728 0.272 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.728 0.272 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.727 0.273 0.000
Z93.0 Tracheostomy status
0.726 0.274 0.000
M34 Systemic sclerosis
0.725 0.275 0.000
C15 Malignant neoplasm of oesophagus
0.725 0.275 0.000
Q66 Congenital deformities of feet
0.724 0.276 0.000
Q21 Congenital malformations of cardiac septa
0.723 0.277 0.000
M85 Other disorders of bone density and structure
0.722 0.278 0.000
C44.7 Skin of lower limb, including hip
0.722 0.278 0.000
S36 Injury of intra-abdominal organs
0.721 0.278 0.000
S50-S59 Injuries to the elbow and forearm
0.721 0.279 0.000
M88 Paget's disease of bone [osteitis deformans]
0.718 0.282 0.000
Q27 Other congenital malformations of peripheral vascular system
0.718 0.282 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.717 0.283 0.000
M67 Other disorders of synovium and tendon
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
U80.8 Agent resistant to other penicillin-related antibiotic
0.717 0.283 0.000
C44.8 Overlapping lesion of skin
0.716 0.283 0.000
M32 Systemic lupus erythematosus
0.716 0.284 0.000
G60 Hereditary and idiopathic neuropathy
0.716 0.284 0.000
M24.16 Other articular cartilage disorders (Lower leg)
0.716 0.284 0.000
C17 Malignant neoplasm of small intestine
0.714 0.285 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.714 0.286 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.714 0.286 0.000
Z84 Family history of other conditions
0.713 0.287 0.000
C18.3 Hepatic flexure
0.713 0.287 0.000
T81.6 Acute reaction to foreign substance accidentally left during a procedure
0.712 0.288 0.000
Z94.8 Other transplanted organ and tissue status
0.712 0.288 0.000
T79-T79 Certain early complications of trauma
0.712 0.288 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.712 0.288 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.710 0.290 0.000
S20-S29 Injuries to the thorax
0.710 0.290 0.000
Z91.7 Personal history of female genital mutilation
0.710 0.290 0.000
Z91.4 Personal history of psychological trauma, not elsewhere classified
0.710 0.290 0.000
Z91.3 Personal history of unhealthy sleep-wake schedule
0.710 0.290 0.000
Z91.2 Personal history of poor personal hygiene
0.710 0.290 0.000
T83.0 Mechanical complication of urinary (indwelling) catheter
0.709 0.291 0.000
T83.3 Mechanical complication of intra-uterine contraceptive device
0.709 0.291 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.708 0.292 0.000
S31.4 Open wound of vagina and vulva
0.708 0.292 0.000
E20-E35 Disorders of other endocrine glands
0.708 0.292 0.000
M89.0 Algoneurodystrophy
0.704 0.296 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.704 0.296 0.000
M80.5 Idiopathic osteoporosis with pathological fracture
0.703 0.297 0.000
M49 Spondylopathies in diseases classified elsewhere
0.703 0.297 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.701 0.299 0.000
Q35-Q37 Cleft lip and cleft palate
0.701 0.299 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.701 0.299 0.000
C21.1 Anal canal
0.701 0.299 0.000
T81.9 Unspecified complication of procedure
0.700 0.300 0.000
Q07 Other congenital malformations of nervous system
0.700 0.300 0.000
M80.9 Unspecified osteoporosis with pathological fracture
0.699 0.301 0.000
Z90.3 Acquired absence of part of stomach
0.697 0.303 0.000
S91 Open wound of ankle and foot
0.697 0.303 0.000
S32.3 Fracture of ilium
0.697 0.303 0.000
Q60-Q64 Congenital malformations of the urinary system
0.697 0.303 0.000
C43.4 Malignant melanoma of scalp and neck
0.697 0.303 0.000
Z93.5 Cystostomy status
0.696 0.304 0.000
M00-M03 Infectious arthropathies
0.696 0.304 0.000
Z93.8 Other artificial opening status
0.696 0.304 0.000
C18.8 Overlapping lesion of colon
0.695 0.304 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.694 0.306 0.000
M33 Dermatopolymyositis
0.694 0.306 0.000
M30 Polyarteritis nodosa and related conditions
0.694 0.306 0.000
Z87.6 Personal history of certain conditions arising in the perinatal period
0.693 0.307 0.000
S42.2 Fracture of upper end of humerus
0.693 0.307 0.000
Z97.4 Presence of external hearing-aid
0.691 0.309 0.000
M46.9 Inflammatory spondylopathy, unspecified
0.691 0.309 0.000
S31.1 Open wound of abdominal wall
0.691 0.309 0.000
Z70 Counselling related to sexual attitude, behaviour and orientation
0.690 0.310 0.000
S32.00 Fracture of lumbar vertebra (closed)
0.689 0.311 0.000
Q76 Congenital malformations of spine and bony thorax
0.688 0.312 0.000
C49 Malignant neoplasm of other connective and soft tissue
0.687 0.313 0.000
M21.1 Varus deformity, not elsewhere classified
0.686 0.314 0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis
0.684 0.316 0.000
S37 Injury of urinary and pelvic organs
0.684 0.316 0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level
0.684 0.316 0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level
0.684 0.316 0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis
0.684 0.316 0.000
M24.9 Joint derangement, unspecified
0.683 0.317 0.000
M24.7 Protrusio acetabuli
0.683 0.317 0.000
M24.6 Ankylosis of joint
0.683 0.317 0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified
0.683 0.317 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.683 0.317 0.000
S48 Traumatic amputation of shoulder and upper arm
0.681 0.319 0.000
S45 Injury of blood vessels at shoulder and upper arm level
0.681 0.319 0.000
S44 Injury of nerves at shoulder and upper arm level
0.681 0.319 0.000
S47 Crushing injury of shoulder and upper arm
0.681 0.319 0.000
U88 Agent resistant to multiple antibiotics
0.680 0.320 0.000
Z74.2 Need for assistance at home and no other household member able to render care
0.680 0.320 0.000
Z71.2 Person consulting for explanation of investigation findings
0.679 0.321 0.000
S32.10 Fracture of sacrum (closed)
0.678 0.322 0.000
M23.24 Derangement of meniscus due to old tear or injury (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.678 0.322 0.000
Z87.5 Personal history of complications of pregnancy, childbirth and the puerperium
0.677 0.323 0.000
M66.0 Rupture of popliteal cyst
0.677 0.323 0.000
Z99.3 Dependence on wheelchair
0.676 0.323 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.676 0.324 0.000
M89.95 Disorder of bone, unspecified (Pelvic region and thigh)
0.676 0.324 0.000
M65.9 Synovitis and tenosynovitis, unspecified
0.676 0.324 0.000
Z88.7 Personal history of allergy to serum and vaccine
0.675 0.325 0.000
Z71.7 Human immunodeficiency virus [HIV] counselling
0.674 0.326 0.000
Z71.6 Tobacco abuse counselling
0.674 0.326 0.000
Z71.5 Drug abuse counselling and surveillance
0.674 0.326 0.000
Z71.0 Person consulting on behalf of another person
0.674 0.326 0.000
M83 Adult osteomalacia
0.673 0.327 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.673 0.327 0.000
H60.9 Otitis externa, unspecified
0.672 0.328 0.000
M87.9 Osteonecrosis, unspecified
0.672 0.328 0.000
M24.87 Other specific joint derangements, not elsewhere classified (Ankle and foot)
0.672 0.328 0.000
C23 Malignant neoplasm of gallbladder
0.672 0.328 0.000
Z91.5 Personal history of self-harm
0.671 0.329 0.000
D04.9 Skin, unspecified
0.671 0.329 0.000
M96.1 Postlaminectomy syndrome, not elsewhere classified
0.671 0.329 0.000
M23.29 Derangement of meniscus due to old tear or injury (Unspecified ligament or Unspecified meniscus)
0.671 0.329 0.000
G93.3 Postviral fatigue syndrome
0.669 0.331 0.000
M89.92 Disorder of bone, unspecified (Upper arm)
0.668 0.332 0.000
U81 Agent resistant to vancomycin and related antibiotics
0.667 0.333 0.000
U50 Level of care administered to neonates
0.667 0.333 0.000
U07 Emergency use of U07
0.667 0.333 0.000
U06 Emergency use of U06
0.667 0.333 0.000
U04 Severe acute respiratory syndrome [SARS]
0.667 0.333 0.000
U52 First in a series of a regular day/night admissions
0.667 0.333 0.000
M23.5 Chronic instability of knee
0.667 0.333 0.000
S42.9 Fracture of shoulder girdle, part unspecified
0.667 0.333 0.000
S42.8 Fracture of other parts of shoulder and upper arm
0.667 0.333 0.000
S42.7 Multiple fractures of clavicle, scapula and humerus
0.667 0.333 0.000
Q28 Other congenital malformations of circulatory system
0.667 0.333 0.000
M89.97 Disorder of bone, unspecified (Ankle and foot)
0.666 0.334 0.000
Z74.0 Reduced mobility
0.665 0.335 0.000
D02 Carcinoma in situ of middle ear and respiratory system
0.665 0.335 0.000
D01 Carcinoma in situ of other and unspecified digestive organs
0.665 0.335 0.000
Z91.6 Personal history of other physical trauma
0.664 0.336 0.000
T19 Foreign body in genito-urinary tract
0.664 0.336 0.000
T15 Foreign body on external eye
0.664 0.336 0.000
M96.8 Other postprocedural musculoskeletal disorders
0.664 0.336 0.000
Z94.9 Transplanted organ and tissue status, unspecified
0.664 0.336 0.000
Z94.6 Bone transplant status
0.664 0.336 0.000
Z94.5 Skin transplant status
0.664 0.336 0.000
Z94.3 Heart and lungs transplant status
0.664 0.336 0.000
Z94.2 Lung transplant status
0.664 0.336 0.000
V40-V49 Car occupant injured in transport accident
0.662 0.337 0.000
C43.9 Malignant melanoma of skin, unspecified
0.662 0.338 0.000
Z97.3 Presence of spectacles and contact lenses
0.661 0.339 0.000
T86.0 Bone-marrow transplant rejection
0.660 0.340 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.658 0.342 0.000
D04.3 Skin of other and unspecified parts of face
0.658 0.342 0.000
M80.00 Postmenopausal osteoporosis with pathological fracture (Multiple sites)
0.657 0.343 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.656 0.344 0.000
M24.47 Recurrent dislocation and subluxation of joint (Ankle and foot)
0.655 0.345 0.000
M99 Biomechanical lesions, not elsewhere classified
0.653 0.347 0.000
C18.4 Transverse colon
0.653 0.347 0.000
Z22 Carrier of infectious disease
0.653 0.347 0.000
M90.7 Fracture of bone in neoplastic disease
0.652 0.348 0.000
M24.15 Other articular cartilage disorders (Pelvic region and thigh)
0.652 0.348 0.000
C21.8 Overlapping lesion of rectum, anus and anal canal
0.651 0.349 0.000
C21.2 Cloacogenic zone
0.651 0.349 0.000
M82 Osteoporosis in diseases classified elsewhere
0.651 0.349 0.000
M23.0 Cystic meniscus
0.650 0.349 0.000
M23.9 Internal derangement of knee, unspecified
0.650 0.350 0.000
C91 Lymphoid leukaemia
0.650 0.350 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.650 0.350 0.000
M89.6 Osteopathy after poliomyelitis
0.649 0.350 0.000
M89.5 Osteolysis
0.649 0.350 0.000
M89.4 Other hypertrophic osteo-arthropathy
0.649 0.350 0.000
M89.3 Hypertrophy of bone
0.649 0.350 0.000
M89.2 Other disorders of bone development and growth
0.649 0.350 0.000
M89.1 Epiphyseal arrest
0.649 0.350 0.000
Q80-Q89 Other congenital malformations
0.649 0.351 0.000
C16.8 Overlapping lesion of stomach
0.649 0.351 0.000
C16.6 Greater curvature of stomach, unspecified
0.649 0.351 0.000
C16.4 Pylorus
0.649 0.351 0.000
C16.3 Pyloric antrum
0.649 0.351 0.000
C16.2 Body of stomach
0.649 0.351 0.000
C16.1 Fundus of stomach
0.649 0.351 0.000
G93.4 Encephalopathy, unspecified
0.648 0.352 0.000
G99.2 Myelopathy in diseases classified elsewhere
0.648 0.352 0.000
Z94.0 Kidney transplant status
0.647 0.353 0.000
V70-V79 Bus occupant injured in transport accident
0.647 0.353 0.000
M95.0 Acquired deformity of nose
0.647 0.353 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.647 0.353 0.000
E10-E14 Diabetes mellitus
0.647 0.353 0.000
Z90.5 Acquired absence of kidney
0.647 0.353 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.647 0.353 0.000
C26.0 Intestinal tract, part unspecified
0.646 0.354 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.646 0.354 0.000
Q05 Spina bifida
0.645 0.355 0.000
T86.4 Liver transplant failure and rejection
0.645 0.355 0.000
S39.9 Unspecified injury of abdomen, lower back and pelvis
0.644 0.356 0.000
Z29 Need for other prophylactic measures
0.643 0.357 0.000
H82 Vertiginous syndromes in diseases classified elsewhere
0.642 0.358 0.000
C16.0 Cardia
0.642 0.358 0.000
T80.8 Other complications following infusion, transfusion and therapeutic injection
0.642 0.358 0.000
C77.0 Lymph nodes of head, face and neck
0.641 0.359 0.000
S32.4 Fracture of acetabulum
0.641 0.359 0.000
Q26 Congenital malformations of great veins
0.639 0.361 0.000
Q25 Congenital malformations of great arteries
0.639 0.361 0.000
Q22 Congenital malformations of pulmonary and tricuspid valves
0.639 0.361 0.000
Q20 Congenital malformations of cardiac chambers and connexions
0.639 0.361 0.000
M46.96 Inflammatory spondylopathy, unspecified (Lumbar region)
0.638 0.361 0.000
Z74.8 Other problems related to care-provider dependency
0.638 0.362 0.000
U89 Agent resistant to other and unspecified antibiotics
0.637 0.362 0.000
C10 Malignant neoplasm of oropharynx
0.637 0.363 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.637 0.363 0.000
Q66.8 Other congenital deformities of feet
0.637 0.363 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.637 0.363 0.000
T13 Other injuries of lower limb, level unspecified
0.636 0.364 0.000
T11 Other injuries of upper limb, level unspecified
0.636 0.364 0.000
T09 Other injuries of spine and trunk, level unspecified
0.636 0.364 0.000
T12.X1 Fracture of lower limb, level unspecified (open)
0.636 0.364 0.000
T12.X0 Fracture of lower limb, level unspecified (closed)
0.636 0.364 0.000
T12 Fracture of lower limb, level unspecified
0.636 0.364 0.000
T10.X1 Fracture of upper limb, level unspecified (open)
0.636 0.364 0.000
T10.X0 Fracture of upper limb, level unspecified (closed)
0.636 0.364 0.000
T10 Fracture of upper limb, level unspecified
0.636 0.364 0.000
T08.X1 Fracture of spine, level unspecified (open)
0.636 0.364 0.000
T08.X0 Fracture of spine, level unspecified (closed)
0.636 0.364 0.000
T08 Fracture of spine, level unspecified
0.636 0.364 0.000
M35 Other systemic involvement of connective tissue
0.636 0.364 0.000
G95 Other diseases of spinal cord
0.635 0.365 0.000
M24.02 Loose body in joint (Upper arm)
0.634 0.366 0.000
M23.1 Discoid meniscus (congenital)
0.634 0.366 0.000
T31 Burns classified according to extent of body surface involved
0.633 0.367 0.000
M86 Osteomyelitis
0.633 0.367 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.632 0.368 0.000
S42.01 Fracture of clavicle (open)
0.632 0.368 0.000
S99 Other and unspecified injuries of ankle and foot
0.632 0.368 0.000
G56 Mononeuropathies of upper limb
0.631 0.369 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.631 0.369 0.000
H83.9 Disease of inner ear, unspecified
0.631 0.369 0.000
H83.8 Other specified diseases of inner ear
0.631 0.369 0.000
H83.3 Noise effects on inner ear
0.631 0.369 0.000
H83.2 Labyrinthine dysfunction
0.631 0.369 0.000
H83.1 Labyrinthine fistula
0.631 0.369 0.000
M24.86 Other specific joint derangements, not elsewhere classified (Lower leg)
0.630 0.370 0.000
T66-T78 Other and unspecified effects of external causes
0.630 0.370 0.000
T81.7 Vascular complications following a procedure, not elsewhere classified
0.629 0.371 0.000
S41 Open wound of shoulder and upper arm
0.629 0.371 0.000
Z76.8 Persons encountering health services in other specified circumstances
0.628 0.371 0.000
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot
0.628 0.371 0.000
S32.2 Fracture of coccyx
0.628 0.372 0.000
D06.7 Other parts of cervix
0.628 0.372 0.000
D06.1 Exocervix
0.628 0.372 0.000
D06.0 Endocervix
0.628 0.372 0.000
M24.13 Other articular cartilage disorders (Forearm)
0.628 0.372 0.000
C01 Malignant neoplasm of base of tongue
0.628 0.372 0.000
M23.27 Derangement of meniscus due to old tear or injury-Capsular
0.626 0.374 0.000
T17 Foreign body in respiratory tract
0.626 0.374 0.000
M84.0 Malunion of fracture
0.625 0.375 0.000
Q51 Congenital malformations of uterus and cervix
0.625 0.375 0.000
Z73.6 Limitation of activities due to disability
0.624 0.376 0.000
M67.8 Other specified disorders of synovium and tendon
0.624 0.376 0.000
M22.4 Chondromalacia patellae
0.623 0.377 0.000
E11 Non-insulin-dependent diabetes mellitus
0.623 0.377 0.000
S42.30 Fracture of shaft of humerus (closed)
0.623 0.377 0.000
M91-M94 Chondropathies
0.623 0.377 0.000
M89.88 Other specified disorders of bone (Other)
0.623 0.377 0.000
T87.4 Infection of amputation stump
0.623 0.377 0.000
S20 Superficial injury of thorax
0.622 0.378 0.000
Z98.2 Presence of cerebrospinal fluid drainage device
0.622 0.378 0.000
Q24 Other congenital malformations of heart
0.621 0.379 0.000
G62.0 Drug-induced polyneuropathy
0.621 0.379 0.000
M22.2 Patellofemoral disorders
0.620 0.380 0.000
C45 Mesothelioma
0.620 0.380 0.000
M66.4 Spontaneous rupture of other tendons
0.620 0.380 0.000
H91 Other hearing loss
0.620 0.380 0.000
T21 Burn and corrosion of trunk
0.619 0.381 0.000
T18.9 Foreign body in alimentary tract, part unspecified
0.618 0.382 0.000
T18.8 Foreign body in other and multiple parts of alimentary tract
0.618 0.382 0.000
T18.5 Foreign body in anus and rectum
0.618 0.382 0.000
T18.4 Foreign body in colon
0.618 0.382 0.000
T18.3 Foreign body in small intestine
0.618 0.382 0.000
T18.2 Foreign body in stomach
0.618 0.382 0.000
T18.0 Foreign body in mouth
0.618 0.382 0.000
Z89 Acquired absence of limb
0.618 0.382 0.000
D04.4 Skin of scalp and neck
0.617 0.382 0.000
T86.1 Kidney transplant failure and rejection
0.617 0.383 0.000
W50-W64 Exposure to animate mechanical forces
0.617 0.383 0.000
M80.8 Other osteoporosis with pathological fracture
0.617 0.383 0.000
M80.4 Drug-induced osteoporosis with pathological fracture
0.617 0.383 0.000
M80.3 Postsurgical malabsorption osteoporosis with pathological fracture
0.617 0.383 0.000
M80.2 Osteoporosis of disuse with pathological fracture
0.617 0.383 0.000
C77.4 Inguinal and lower limb lymph nodes
0.617 0.383 0.000
C43.8 Overlapping malignant melanoma of skin
0.616 0.383 0.000
C43.2 Malignant melanoma of ear and external auricular canal
0.616 0.383 0.000
C43.1 Malignant melanoma of eyelid, including canthus
0.616 0.383 0.000
C43.0 Malignant melanoma of lip
0.616 0.383 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.617 0.383 0.000
G56.0 Carpal tunnel syndrome
0.616 0.384 0.000
M24.26 Disorder of ligament (Lower leg)
0.616 0.384 0.000
G61 Inflammatory polyneuropathy
0.615 0.385 0.000
Z83 Family history of other specific disorders
0.615 0.385 0.000
Z81.8 Family history of other mental and behavioural disorders
0.615 0.385 0.000
C77.9 Lymph node, unspecified
0.614 0.386 0.000
S39.0 Injury of muscle and tendon of abdomen, lower back and pelvis
0.614 0.386 0.000
M50-M54 Other dorsopathies
0.614 0.386 0.000
G71 Primary disorders of muscles
0.613 0.387 0.000
Z99.9 Dependence on unspecified enabling machine and device
0.613 0.387 0.000
Z99.4 Dependence on artificial heart
0.613 0.387 0.000
Z99.0 Dependence on aspirator
0.613 0.387 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.613 0.387 0.000
S40 Superficial injury of shoulder and upper arm
0.613 0.387 0.000
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)
0.612 0.388 0.000
S92 Fracture of foot, except ankle
0.612 0.388 0.000
C66 Malignant neoplasm of ureter
0.611 0.389 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.611 0.389 0.000
G64 Other disorders of peripheral nervous system
0.611 0.389 0.000
H60.1 Cellulitis of external ear
0.611 0.389 0.000
Z73.8 Other problems related to life-management difficulty
0.611 0.389 0.000
Q23.1 Congenital insufficiency of aortic valve
0.611 0.389 0.000
S70-S79 Injuries to the hip and thigh
0.610 0.390 0.000
M65.91 Synovitis and tenosynovitis, unspecified (Shoulder region)
0.610 0.390 0.000
Z87.3 Personal history of diseases of the musculoskeletal system and connective tissue
0.610 0.390 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.609 0.391 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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