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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs111785063
log Bayes Factor = 7.71115
Chromosome 19   position 22,646,085  (GRCh37) Explore rs111785063 on Ensembl!
Variant rs111785063 is part of Cluster X0052

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
M20-M25 Other joint disorders
1.000 0.000 0.000
M25 Other joint disorders, not elsewhere classified
0.997 0.003 0.000
M23 Internal derangement of knee
0.996 0.004 0.000
Chapter II Neoplasms
0.996 0.004 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.994 0.006 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.993 0.007 0.000
M25.7 Osteophyte
0.993 0.007 0.000
Chapter V Mental and behavioural disorders
0.992 0.008 0.000
M25.77 Osteophyte (Ankle and foot)
0.991 0.009 0.000
M23.3 Other meniscus derangements
0.983 0.017 0.000
C15-C26 Malignant neoplasms of digestive organs
0.978 0.022 0.000
Chapter XX External causes of morbidity and mortality
0.976 0.024 0.000
Q60-Q64 Congenital malformations of the urinary system
0.973 0.027 0.000
D10-D36 Benign neoplasms
0.970 0.030 0.000
C15 Malignant neoplasm of oesophagus
0.968 0.032 0.000
M80-M85 Disorders of bone density and structure
0.963 0.037 0.000
Chapter VI Diseases of the nervous system
0.963 0.037 0.000
D35 Benign neoplasm of other and unspecified endocrine glands
0.958 0.042 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.958 0.042 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.950 0.050 0.000
D23 Other benign neoplasms of skin
0.949 0.051 0.000
S80-S89 Injuries to the knee and lower leg
0.943 0.057 0.000
M50-M54 Other dorsopathies
0.938 0.062 0.000
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)
0.934 0.066 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.930 0.070 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.924 0.076 0.000
C60-C63 Malignant neoplasms of male genital organs
0.923 0.077 0.000
Q63 Other congenital malformations of kidney
0.916 0.084 0.000
C15.9 Oesophagus, unspecified
0.910 0.090 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.906 0.094 0.000
Q61 Cystic kidney disease
0.905 0.095 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.904 0.096 0.000
O60-O75 Complications of labour and delivery
0.904 0.096 0.000
D35.2 Pituitary gland
0.899 0.101 0.000
M25.78 Osteophyte (Other)
0.898 0.102 0.000
D48.5 Skin
0.898 0.102 0.000
F30-F39 Mood [affective] disorders
0.897 0.103 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.896 0.104 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.894 0.106 0.000
Q50-Q56 Congenital malformations of genital organs
0.893 0.107 0.000
S90-S99 Injuries to the ankle and foot
0.890 0.110 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.889 0.111 0.000
O72 Postpartum haemorrhage
0.889 0.111 0.000
M40-M43 Deforming dorsopathies
0.887 0.113 0.000
D35.1 Parathyroid gland
0.887 0.113 0.000
M54 Dorsalgia
0.887 0.113 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.885 0.115 0.000
C15.5 Lower third of oesophagus
0.884 0.116 0.000
C61 Malignant neoplasm of prostate
0.883 0.117 0.000
T66-T78 Other and unspecified effects of external causes
0.882 0.118 0.000
M84 Disorders of continuity of bone
0.881 0.119 0.000
F20 Schizophrenia
0.881 0.119 0.000
O72.1 Other immediate postpartum haemorrhage
0.881 0.119 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.877 0.123 0.000
E20-E35 Disorders of other endocrine glands
0.873 0.127 0.000
C16 Malignant neoplasm of stomach
0.869 0.131 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.869 0.131 0.000
Q63.0 Accessory kidney
0.866 0.134 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.866 0.134 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.863 0.137 0.000
M23.30 Other meniscus derangements (Multiple sites)
0.863 0.137 0.000
M24 Other specific joint derangements
0.860 0.140 0.000
M23.34 Other meniscus derangements (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.859 0.141 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.857 0.143 0.000
D23.7 Skin of lower limb, including hip
0.854 0.146 0.000
D46 Myelodysplastic syndromes
0.853 0.147 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.850 0.150 0.000
S82 Fracture of lower leg, including ankle
0.849 0.151 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.849 0.151 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.848 0.152 0.000
M23.35 Other meniscus derangements (Posterior horn of lateral meniscus)
0.847 0.153 0.000
D23.3 Skin of other and unspecified parts of face
0.842 0.158 0.000
X60-X84 Intentional self-harm
0.840 0.160 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.835 0.165 0.000
M91-M94 Chondropathies
0.835 0.165 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.834 0.166 0.000
M25.5 Pain in joint
0.834 0.166 0.000
Chapter VIII Diseases of the ear and mastoid process
0.832 0.168 0.000
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)
0.832 0.168 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.831 0.169 0.000
F31 Bipolar affective disorder
0.831 0.169 0.000
M23.4 Loose body in knee
0.829 0.171 0.000
F80-F89 Disorders of psychological development
0.828 0.172 0.000
F23 Acute and transient psychotic disorders
0.821 0.179 0.000
M54.3 Sciatica
0.821 0.179 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.820 0.180 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.820 0.180 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.816 0.184 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.815 0.185 0.000
M32 Systemic lupus erythematosus
0.814 0.186 0.000
C23 Malignant neoplasm of gallbladder
0.812 0.188 0.000
C15.0 Cervical part of oesophagus
0.810 0.190 0.000
D35.0 Adrenal gland
0.810 0.190 0.000
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)
0.809 0.191 0.000
M54.1 Radiculopathy
0.809 0.191 0.000
M84.0 Malunion of fracture
0.806 0.194 0.000
C17 Malignant neoplasm of small intestine
0.802 0.198 0.000
D14 Benign neoplasm of middle ear and respiratory system
0.802 0.198 0.000
M85 Other disorders of bone density and structure
0.801 0.199 0.000
M25.61 Stiffness of joint, not elsewhere classified (Shoulder region)
0.799 0.201 0.000
D32 Benign neoplasm of meninges
0.796 0.204 0.000
M80 Osteoporosis with pathological fracture
0.795 0.205 0.000
F25 Schizoaffective disorders
0.795 0.205 0.000
C64-C68 Malignant neoplasms of urinary tract
0.793 0.207 0.000
S82.3 Fracture of lower end of tibia
0.793 0.207 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.792 0.208 0.000
F20.9 Schizophrenia, unspecified
0.792 0.208 0.000
V40-V49 Car occupant injured in transport accident
0.791 0.209 0.000
D31 Benign neoplasm of eye and adnexa
0.790 0.210 0.000
Chapter XXII Codes for special purposes
0.788 0.212 0.000
D11 Benign neoplasm of major salivary glands
0.785 0.215 0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments
0.785 0.215 0.000
M43 Other deforming dorsopathies
0.785 0.215 0.000
G83 Other paralytic syndromes
0.784 0.215 0.000
S70-S79 Injuries to the hip and thigh
0.782 0.218 0.000
M25.72 Osteophyte (Upper arm)
0.781 0.219 0.000
D21 Other benign neoplasms of connective and other soft tissue
0.780 0.220 0.000
C15.4 Middle third of oesophagus
0.779 0.220 0.000
E00-E07 Disorders of thyroid gland
0.779 0.221 0.000
T31 Burns classified according to extent of body surface involved
0.779 0.221 0.000
F05 Delirium, not induced by alcohol and other psychoactive substances
0.779 0.221 0.000
F60-F69 Disorders of adult personality and behaviour
0.778 0.222 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.778 0.222 0.000
M30 Polyarteritis nodosa and related conditions
0.777 0.222 0.000
Q80-Q89 Other congenital malformations
0.776 0.223 0.000
D16 Benign neoplasm of bone and articular cartilage
0.775 0.225 0.000
Q61.3 Polycystic kidney, unspecified
0.775 0.225 0.000
T78 Adverse effects, not elsewhere classified
0.773 0.227 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.773 0.227 0.000
V10-V19 Pedal cyclist injured in transport accident
0.772 0.228 0.000
M25.3 Other instability of joint
0.768 0.232 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.767 0.233 0.000
S92 Fracture of foot, except ankle
0.766 0.234 0.000
G08 Intracranial and intraspinal phlebitis and thrombophlebitis
0.765 0.235 0.000
M21 Other acquired deformities of limbs
0.765 0.235 0.000
C16.0 Cardia
0.763 0.237 0.000
G82 Paraplegia and tetraplegia
0.763 0.237 0.000
E40-E46 Malnutrition
0.763 0.237 0.000
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care
0.762 0.238 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.762 0.238 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.760 0.240 0.000
F00 Dementia in Alzheimer's disease
0.759 0.241 0.000
M25.0 Haemarthrosis
0.759 0.241 0.000
D23.1 Skin of eyelid, including canthus
0.759 0.241 0.000
Q61.2 Polycystic kidney, adult type
0.757 0.243 0.000
E28 Ovarian dysfunction
0.757 0.243 0.000
D23.6 Skin of upper limb, including shoulder
0.756 0.244 0.000
M24.1 Other articular cartilage disorders
0.755 0.245 0.000
F99-F99 Unspecified mental disorder
0.752 0.248 0.000
E21.3 Hyperparathyroidism, unspecified
0.752 0.248 0.000
Q00-Q07 Congenital malformations of the nervous system
0.752 0.248 0.000
X20-X29 Contact with venomous animals and plants
0.751 0.249 0.000
M51 Other intervertebral disk disorders
0.748 0.252 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.748 0.252 0.000
M25.53 Pain in joint (Forearm)
0.747 0.253 0.000
M60-M63 Disorders of muscles
0.747 0.253 0.000
X10-X19 Contact with heat and hot substances
0.745 0.255 0.000
M05-M14 Inflammatory polyarthropathies
0.745 0.255 0.000
M54.16 Radiculopathy (Lumbar region)
0.744 0.256 0.000
V80-V89 Other land transport accidents
0.744 0.256 0.000
F20.0 Paranoid schizophrenia
0.744 0.256 0.000
G04 Encephalitis, myelitis and encephalomyelitis
0.743 0.257 0.000
C73 Malignant neoplasm of thyroid gland
0.742 0.258 0.000
G03 Meningitis due to other and unspecified causes
0.742 0.258 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.742 0.258 0.000
F01 Vascular dementia
0.741 0.259 0.000
M54.4 Lumbago with sciatica
0.740 0.260 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.740 0.260 0.000
S81 Open wound of lower leg
0.739 0.261 0.000
G20-G26 Extrapyramidal and movement disorders
0.739 0.261 0.000
T79-T79 Certain early complications of trauma
0.739 0.261 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.738 0.262 0.000
Q61.0 Congenital single renal cyst
0.738 0.262 0.000
M82 Osteoporosis in diseases classified elsewhere
0.737 0.263 0.000
M22 Disorders of patella
0.737 0.263 0.000
F31.9 Bipolar affective disorder, unspecified
0.736 0.264 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.736 0.264 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.735 0.265 0.000
M84.03 Malunion of fracture (Forearm)
0.735 0.265 0.000
D46.9 Myelodysplastic syndrome, unspecified
0.735 0.265 0.000
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee
0.735 0.265 0.000
S82.30 Fracture of lower end of tibia (closed)
0.734 0.266 0.000
D23.4 Skin of scalp and neck
0.733 0.267 0.000
M25.66 Stiffness of joint, not elsewhere classified (Lower leg)
0.731 0.269 0.000
M25.51 Pain in joint (Shoulder region)
0.731 0.269 0.000
D23.0 Skin of lip
0.731 0.269 0.000
F23.9 Acute and transient psychotic disorder, unspecified
0.729 0.271 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.728 0.272 0.000
M23.9 Internal derangement of knee, unspecified
0.728 0.272 0.000
D23.9 Skin, unspecified
0.728 0.272 0.000
Y00-Y09 Assault
0.727 0.273 0.000
M45-M49 Spondylopathies
0.727 0.273 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.727 0.273 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.726 0.274 0.000
G54 Nerve root and plexus disorders
0.725 0.275 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.724 0.276 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.723 0.277 0.000
G00 Bacterial meningitis, not elsewhere classified
0.723 0.277 0.000
D48.0 Bone and articular cartilage
0.721 0.279 0.000
S82.4 Fracture of fibula alone
0.721 0.279 0.000
D30 Benign neoplasm of urinary organs
0.720 0.280 0.000
V20-V29 Motorcycle rider injured in transport accident
0.720 0.280 0.000
Y57 Other and unspecified drugs and medicaments
0.719 0.281 0.000
G55.2 Nerve root and plexus compressions in spondylosis
0.718 0.282 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.717 0.283 0.000
M33 Dermatopolymyositis
0.717 0.283 0.000
M54.36 Sciatica (Lumbar region)
0.716 0.284 0.000
D28 Benign neoplasm of other and unspecified female genital organs
0.716 0.284 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.715 0.285 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.715 0.285 0.000
M25.2 Flail joint
0.715 0.285 0.000
M25.1 Fistula of joint
0.715 0.285 0.000
T31.0 Burns involving less than 10% of body surface
0.715 0.285 0.000
D36 Benign neoplasm of other and unspecified sites
0.715 0.285 0.000
G40-G47 Episodic and paroxysmal disorders
0.714 0.286 0.000
M23.1 Discoid meniscus (congenital)
0.714 0.286 0.000
M23.0 Cystic meniscus
0.714 0.286 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.714 0.286 0.000
M93 Other osteochondropathies
0.714 0.286 0.000
S86 Injury of muscle and tendon at lower leg level
0.713 0.287 0.000
T33-T35 Frostbite
0.713 0.287 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.713 0.287 0.000
T00-T07 Injuries involving multiple body regions
0.713 0.287 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.712 0.288 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.712 0.288 0.000
Q35-Q37 Cleft lip and cleft palate
0.712 0.288 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.712 0.288 0.000
M25.79 Osteophyte (Site unspecified)
0.712 0.288 0.000
M25.73 Osteophyte (Forearm)
0.712 0.288 0.000
M25.70 Osteophyte (Multiple sites)
0.712 0.288 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.711 0.289 0.000
F70-F79 Mental retardation
0.711 0.289 0.000
M23.49 Loose body in knee-Unspec lig/men
0.710 0.290 0.000
D48.7 Other specified sites
0.709 0.291 0.000
M25.59 Pain in joint (Site unspecified)
0.709 0.291 0.000
Q50.4 Embryonic cyst of Fallopian tube
0.708 0.292 0.000
X50-X57 Overexertion, travel and privation
0.708 0.292 0.000
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx
0.708 0.292 0.000
S83.6 Sprain and strain of other and unspecified parts of knee
0.708 0.292 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.708 0.292 0.000
M43.1 Spondylolisthesis
0.707 0.293 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.707 0.293 0.000
Q63.1 Lobulated, fused and horseshoe kidney
0.707 0.293 0.000
S83.4 Sprain and strain involving (fibular)(tibial) collateral ligamnent of knee
0.706 0.294 0.000
F81 Specific developmental disorders of scholastic skills
0.706 0.294 0.000
E24 Cushing's syndrome
0.705 0.295 0.000
M23.37 Other meniscus derangements-Capsular lig
0.705 0.295 0.000
M23.31 Other meniscus derangements (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.705 0.295 0.000
G58 Other mononeuropathies
0.704 0.296 0.000
M65-M68 Disorders of synovium and tendon
0.703 0.297 0.000
M00-M03 Infectious arthropathies
0.703 0.297 0.000
H65-H75 Diseases of middle ear and mastoid
0.703 0.297 0.000
M23.25 Derangement of meniscus due to old tear or injury (Posterior horn of lateral meniscus)
0.701 0.299 0.000
Chapter I Certain infectious and parasitic diseases
0.701 0.299 0.000
C51-C58 Malignant neoplasms of female genital organs
0.700 0.300 0.000
Y35-Y36 Legal intervention and operations of war
0.700 0.300 0.000
Y10-Y34 Event of undetermined intent
0.700 0.300 0.000
X85-X99 Assault
0.700 0.300 0.000
X30-X39 Exposure to forces of nature
0.700 0.300 0.000
X00-X09 Exposure to smoke, fire and flames
0.700 0.300 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.700 0.300 0.000
W75-W84 Other accidental threats to breathing
0.700 0.300 0.000
W65-W74 Accidental drowning and submersion
0.700 0.300 0.000
V98-V99 Other and unspecified transport accidents
0.700 0.300 0.000
V95-V97 Air and space transport accidents
0.700 0.300 0.000
V90-V94 Water transport accidents
0.700 0.300 0.000
V70-V79 Bus occupant injured in transport accident
0.700 0.300 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.700 0.300 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.700 0.300 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.700 0.300 0.000
V01-V09 Pedestrian injured in transport accident
0.700 0.300 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.700 0.300 0.000
D46.2 Refractory anaemia with excess of blasts
0.699 0.301 0.000
M23.5 Chronic instability of knee
0.699 0.301 0.000
M23.21 Derangement of meniscus due to old tear or injury (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.698 0.302 0.000
T68 Hypothermia
0.698 0.302 0.000
Q64 Other congenital malformations of urinary system
0.697 0.303 0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter
0.697 0.303 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.697 0.303 0.000
C21 Malignant neoplasm of anus and anal canal
0.697 0.303 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.696 0.304 0.000
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum
0.695 0.305 0.000
D19 Benign neoplasm of mesothelial tissue
0.695 0.305 0.000
D15 Benign neoplasm of other and unspecified intrathoracic organs
0.695 0.305 0.000
M25.75 Osteophyte (Pelvic region and thigh)
0.695 0.305 0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms
0.695 0.305 0.000
X68 Intentional self-poisoning by and exposure to pesticides
0.695 0.305 0.000
C15.8 Overlapping lesion of oesophagus
0.694 0.306 0.000
C15.3 Upper third of oesophagus
0.694 0.306 0.000
C15.2 Abdominal part of oesophagus
0.694 0.306 0.000
C15.1 Thoracic part of oesophagus
0.694 0.306 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.694 0.306 0.000
M50 Cervical disk disorders
0.693 0.307 0.000
T20 Burn and corrosion of head and neck
0.693 0.307 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.692 0.308 0.000
E22 Hyperfunction of pituitary gland
0.691 0.309 0.000
M23.8 Other internal derangements of knee
0.691 0.309 0.000
M83 Adult osteomalacia
0.690 0.309 0.000
E06 Thyroiditis
0.690 0.310 0.000
M41 Scoliosis
0.689 0.311 0.000
O61 Failed induction of labour
0.688 0.312 0.000
C16.9 Stomach, unspecified
0.687 0.313 0.000
D35.9 Endocrine gland, unspecified
0.687 0.313 0.000
D35.8 Pluriglandular involvement
0.687 0.313 0.000
D35.7 Other specified endocrine glands
0.687 0.313 0.000
D35.6 Aortic body and other paraganglia
0.687 0.313 0.000
D35.5 Carotid body
0.687 0.313 0.000
D35.4 Pineal gland
0.687 0.313 0.000
D35.3 Craniopharyngeal duct
0.687 0.313 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.687 0.313 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.687 0.313 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.686 0.313 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.686 0.313 0.000
G83.4 Cauda equina syndrome
0.686 0.314 0.000
M23.61 Other spontaneous disruption of ligament(s) of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.686 0.314 0.000
O85-O92 Complications predominantly related to the puerperium
0.686 0.314 0.000
G50 Disorders of trigeminal nerve
0.684 0.316 0.000
F25.9 Schizoaffective disorder, unspecified
0.684 0.316 0.000
D29 Benign neoplasm of male genital organs
0.683 0.317 0.000
M24.6 Ankylosis of joint
0.682 0.318 0.000
W50-W64 Exposure to animate mechanical forces
0.682 0.318 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.681 0.318 0.000
M10 Gout
0.681 0.319 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.681 0.319 0.000
F28 Other nonorganic psychotic disorders
0.681 0.319 0.000
F24 Induced delusional disorder
0.681 0.319 0.000
F21 Schizotypal disorder
0.681 0.319 0.000
M32.1 Systemic lupus erythematosus with organ or system involvement
0.680 0.320 0.000
O66 Other obstructed labour
0.679 0.321 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.679 0.321 0.000
F30 Manic episode
0.679 0.321 0.000
T14 Injury of unspecified body region
0.679 0.321 0.000
O72.2 Delayed and secondary postpartum haemorrhage
0.678 0.322 0.000
Q60 Renal agenesis and other reduction defects of kidney
0.678 0.322 0.000
Q54 Hypospadias
0.677 0.323 0.000
X67 Intentional self-poisoning by and exposure to other gases and vapours
0.676 0.324 0.000
Y60.0 During surgical operation
0.676 0.324 0.000
S88 Traumatic amputation of lower leg
0.676 0.324 0.000
S87 Crushing injury of lower leg
0.676 0.324 0.000
S85 Injury of blood vessels at lower leg level
0.676 0.324 0.000
S84 Injury of nerves at lower leg level
0.676 0.324 0.000
E04 Other non-toxic goitre
0.676 0.324 0.000
G51 Facial nerve disorders
0.675 0.325 0.000
H90-H95 Other disorders of ear
0.675 0.325 0.000
Y48 Anaesthetics and therapeutic gases
0.675 0.325 0.000
C07 Malignant neoplasm of parotid gland
0.673 0.327 0.000
E28.2 Polycystic ovarian syndrome
0.673 0.327 0.000
D38.1 Trachea, bronchus and lung
0.673 0.327 0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot
0.673 0.327 0.000
Q51 Congenital malformations of uterus and cervix
0.673 0.327 0.000
M81 Osteoporosis without pathological fracture
0.673 0.327 0.000
D32.9 Meninges, unspecified
0.672 0.328 0.000
G70-G73 Diseases of myoneural junction and muscle
0.671 0.329 0.000
G81 Hemiplegia
0.670 0.330 0.000
M85.8 Other specified disorders of bone density and structure
0.670 0.330 0.000
D14.0 Middle ear, nasal cavity and accessory sinuses
0.669 0.331 0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease
0.669 0.331 0.000
Y65 Other misadventures during surgical and medical care
0.667 0.333 0.000
E46 Unspecified protein-energy malnutrition
0.667 0.333 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.667 0.333 0.000
S81.9 Open wound of lower leg, part unspecified
0.667 0.333 0.000
T39.1 4-Aminophenol derivatives
0.666 0.334 0.000
O73 Retained placenta and membranes, without haemorrhage
0.666 0.334 0.000
Q53 Undescended testicle
0.665 0.335 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.664 0.336 0.000
S36 Injury of intra-abdominal organs
0.664 0.336 0.000
E07 Other disorders of thyroid
0.663 0.337 0.000
D48.9 Neoplasms of uncertain or unknown behaviour, unspecified
0.662 0.338 0.000
D48.4 Peritoneum
0.662 0.338 0.000
D48.3 Retroperitoneum
0.662 0.338 0.000
D48.2 Peripheral nerves and autonomic nervous system
0.662 0.338 0.000
C63 Malignant neoplasm of other and unspecified male genital organs
0.662 0.338 0.000
C60 Malignant neoplasm of penis
0.662 0.338 0.000
M54.38 Sciatica (Sacral and sacrococcygeal region)
0.662 0.338 0.000
S82.1 Fracture of upper end of tibia
0.662 0.338 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.662 0.338 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.662 0.338 0.000
S31 Open wound of abdomen, lower back and pelvis
0.661 0.338 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.661 0.338 0.000
D31.0 Conjunctiva
0.660 0.339 0.000
S99 Other and unspecified injuries of ankle and foot
0.660 0.340 0.000
E21.0 Primary hyperparathyroidism
0.660 0.340 0.000
S50-S59 Injuries to the elbow and forearm
0.659 0.341 0.000
M80.9 Unspecified osteoporosis with pathological fracture
0.659 0.341 0.000
D21.0 Connective and other soft tissue of head, face and neck
0.658 0.342 0.000
D23.2 Skin of ear and external auricular canal
0.658 0.342 0.000
G55.1 Nerve root and plexus compressions in intervertebral disk disorders
0.658 0.342 0.000
O63 Long labour
0.658 0.342 0.000
M54.5 Low back pain
0.658 0.342 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.657 0.343 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.657 0.343 0.000
S10-S19 Injuries to the neck
0.657 0.343 0.000
F05.9 Delirium, unspecified
0.657 0.343 0.000
Q63.9 Congenital malformation of kidney, unspecified
0.657 0.343 0.000
Q63.8 Other specified congenital malformations of kidney
0.657 0.343 0.000
Q63.3 Hyperplastic and giant kidney
0.657 0.343 0.000
Q63.2 Ectopic kidney
0.657 0.343 0.000
S40-S49 Injuries to the shoulder and upper arm
0.656 0.344 0.000
B35-B49 Mycoses
0.656 0.344 0.000
F33 Recurrent depressive disorder
0.656 0.344 0.000
D10 Benign neoplasm of mouth and pharynx
0.655 0.344 0.000
D48.6 Breast
0.655 0.345 0.000
F00.9 Dementia in Alzheimer's disease, unspecified
0.655 0.345 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.655 0.345 0.000
M25.9 Joint disorder, unspecified
0.654 0.346 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.653 0.347 0.000
S32 Fracture of lumbar spine and pelvis
0.653 0.347 0.000
E34 Other endocrine disorders
0.653 0.347 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.653 0.347 0.000
C17.2 Ileum
0.652 0.348 0.000
G06 Intracranial and intraspinal abscess and granuloma
0.650 0.350 0.000
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere
0.650 0.350 0.000
G02 Meningitis in other infectious and parasitic diseases classified elsewhere
0.650 0.350 0.000
G09 Sequelae of inflammatory diseases of central nervous system
0.650 0.350 0.000
G07 Intracranial and intraspinal abscess and granuloma in diseases classified elsewhere
0.650 0.350 0.000
G01 Meningitis in bacterial diseases classified elsewhere
0.650 0.350 0.000
E04.9 Non-toxic goitre, unspecified
0.649 0.351 0.000
Q61.9 Cystic kidney disease, unspecified
0.649 0.351 0.000
Q61.8 Other cystic kidney diseases
0.649 0.351 0.000
Q61.5 Medullary cystic kidney
0.649 0.351 0.000
Q61.4 Renal dysplasia
0.649 0.351 0.000
Q61.1 Polycystic kidney, infantile type
0.649 0.351 0.000
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction
0.648 0.352 0.000
F02 Dementia in other diseases classified elsewhere
0.648 0.352 0.000
F09 Unspecified organic or symptomatic mental disorder
0.648 0.352 0.000
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances
0.648 0.352 0.000
M54.37 Sciatica (Lumbosacral region)
0.648 0.352 0.000
O74 Complications of anaesthesia during labour and delivery
0.648 0.352 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.648 0.352 0.000
O60 Preterm delivery
0.648 0.352 0.000
M54.46 Lumbago with sciatica (Lumbar region)
0.647 0.353 0.000
M54.12 Radiculopathy (Cervical region)
0.646 0.354 0.000
M25.57 Pain in joint (Ankle and foot)
0.645 0.355 0.000
D25 Leiomyoma of uterus
0.645 0.355 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.645 0.355 0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms
0.644 0.356 0.000
D27 Benign neoplasm of ovary
0.644 0.356 0.000
F38 Other mood [affective] disorders
0.643 0.357 0.000
F34 Persistent mood [affective] disorders
0.643 0.357 0.000
F39 Unspecified mood [affective] disorder
0.643 0.357 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.643 0.357 0.000
F31.6 Bipolar affective disorder, current episode mixed
0.643 0.357 0.000
S82.31 Fracture of lower end of tibia (open)
0.642 0.358 0.000
M25.69 Stiffness of joint, not elsewhere classified (Site unspecified)
0.641 0.359 0.000
M25.68 Stiffness of joint, not elsewhere classified (Other)
0.641 0.359 0.000
M25.67 Stiffness of joint, not elsewhere classified (Ankle and foot)
0.641 0.359 0.000
M25.65 Stiffness of joint, not elsewhere classified (Pelvic region and thigh)
0.641 0.359 0.000
M25.63 Stiffness of joint, not elsewhere classified (Forearm)
0.641 0.359 0.000
M25.62 Stiffness of joint, not elsewhere classified (Upper arm)
0.641 0.359 0.000
M25.60 Stiffness of joint, not elsewhere classified (Multiple sites)
0.641 0.359 0.000
M24.16 Other articular cartilage disorders (Lower leg)
0.641 0.359 0.000
S93.0 Dislocation of ankle joint
0.641 0.359 0.000
C02 Malignant neoplasm of other and unspecified parts of tongue
0.640 0.360 0.000
Q56 Indeterminate sex and pseudohermaphroditism
0.640 0.360 0.000
Q55 Other congenital malformations of male genital organs
0.640 0.360 0.000
Q52 Other congenital malformations of female genitalia
0.640 0.360 0.000
C05 Malignant neoplasm of palate
0.639 0.361 0.000
O42 Premature rupture of membranes
0.639 0.361 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.639 0.361 0.000
M31 Other necrotising vasculopathies
0.639 0.361 0.000
M21.0 Valgus deformity, not elsewhere classified
0.638 0.361 0.000
S98 Traumatic amputation of ankle and foot
0.638 0.362 0.000
S97 Crushing injury of ankle and foot
0.638 0.362 0.000
S96 Injury of muscle and tendon at ankle and foot level
0.638 0.362 0.000
S95 Injury of blood vessels at ankle and foot level
0.638 0.362 0.000
S94 Injury of nerves at ankle and foot level
0.638 0.362 0.000
F84 Pervasive developmental disorders
0.638 0.362 0.000
M45 Ankylosing spondylitis
0.638 0.362 0.000
O72.3 Postpartum coagulation defects
0.638 0.362 0.000
T39.0 Salicylates
0.637 0.363 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.637 0.363 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.637 0.363 0.000
M42 Spinal osteochondrosis
0.636 0.364 0.000
M40 Kyphosis and lordosis
0.636 0.364 0.000
M10.9 Gout, unspecified
0.636 0.364 0.000
T23 Burn and corrosion of wrist and hand
0.636 0.364 0.000
M54.8 Other dorsalgia
0.636 0.364 0.000
M54.0 Panniculitis affecting regions of neck and back
0.636 0.364 0.000
D16.4 Bones of skull and face
0.636 0.364 0.000
S82.5 Fracture of medial malleolus
0.636 0.364 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.635 0.365 0.000
C22.9 Liver, unspecified
0.635 0.365 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.634 0.365 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.634 0.365 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.634 0.365 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.634 0.365 0.000
T36 Poisoning by systemic antibiotics
0.634 0.365 0.000
M24.0 Loose body in joint
0.634 0.366 0.000
M24.8 Other specific joint derangements, not elsewhere classified
0.634 0.366 0.000
M84.07 Malunion of fracture (Ankle and foot)
0.634 0.366 0.000
D13 Benign neoplasm of other and ill-defined parts of digestive system
0.634 0.366 0.000
C68 Malignant neoplasm of other and unspecified urinary organs
0.634 0.366 0.000
Y57.9 Drug or medicament, unspecified
0.633 0.367 0.000
O62 Abnormalities of forces of labour
0.633 0.367 0.000
T75 Effects of other external causes
0.632 0.368 0.000
T74 Maltreatment syndromes
0.632 0.368 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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