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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs111892515
log Bayes Factor = 12.0702
Chromosome 21   position 23,392,906  (GRCh37) Explore rs111892515 on Ensembl!
Variant rs111892515 is part of Cluster X0057

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XX External causes of morbidity and mortality
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter X Diseases of the respiratory system
1.000 0.000 0.000
J90-J94 Other diseases of pleura
0.997 0.003 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.996 0.004 0.000
Chapter I Certain infectious and parasitic diseases
0.991 0.009 0.000
Chapter II Neoplasms
0.989 0.011 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.988 0.012 0.000
J90 Pleural effusion, not elsewhere classified
0.988 0.012 0.000
J09-J18 Influenza and pneumonia
0.987 0.013 0.000
B95-B98 Bacterial, viral and other infectious agents
0.985 0.015 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.985 0.015 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.980 0.020 0.000
O42 Premature rupture of membranes
0.978 0.022 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.974 0.026 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.971 0.029 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.970 0.030 0.000
Chapter VI Diseases of the nervous system
0.967 0.033 0.000
M05-M14 Inflammatory polyarthropathies
0.965 0.035 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.963 0.037 0.000
M06 Other rheumatoid arthritis
0.956 0.044 0.000
O42.9 Premature rupture of membranes, unspecified
0.955 0.045 0.000
Y83.1 Surgical operation with implant of artificial internal device
0.954 0.046 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.944 0.056 0.000
M06.9 Rheumatoid arthritis, unspecified
0.941 0.059 0.000
S70-S79 Injuries to the hip and thigh
0.931 0.069 0.000
O42.1 Premature rupture of membranes, onset of labour after 24 hours
0.929 0.071 0.000
C64-C68 Malignant neoplasms of urinary tract
0.929 0.071 0.000
Chapter VIII Diseases of the ear and mastoid process
0.928 0.072 0.000
G20-G26 Extrapyramidal and movement disorders
0.924 0.076 0.000
J18 Pneumonia, organism unspecified
0.923 0.077 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.921 0.079 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.920 0.080 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.919 0.081 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.917 0.083 0.000
H90-H95 Other disorders of ear
0.917 0.083 0.000
Y83.2 Surgical operation with anastomosis, bypass or graft
0.913 0.087 0.000
S20-S29 Injuries to the thorax
0.913 0.087 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.910 0.090 0.000
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters
0.908 0.092 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.905 0.095 0.000
H91 Other hearing loss
0.905 0.095 0.000
J91 Pleural effusion in conditions classified elsewhere
0.904 0.096 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.902 0.098 0.000
J93 Pneumothorax
0.897 0.103 0.000
H91.9 Hearing loss, unspecified
0.897 0.103 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.884 0.116 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.884 0.116 0.000
T84.1 Mechanical complication of internal fixation device of bones of limb
0.880 0.120 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.878 0.122 0.000
G20 Parkinson's disease
0.878 0.122 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.873 0.127 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.872 0.128 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.872 0.128 0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters
0.871 0.129 0.000
T92 Sequelae of injuries of upper limb
0.871 0.129 0.000
Chapter VII Diseases of the eye and adnexa
0.869 0.131 0.000
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters
0.863 0.137 0.000
M86-M90 Other osteopathies
0.862 0.138 0.000
J18.1 Lobar pneumonia, unspecified
0.860 0.140 0.000
S90-S99 Injuries to the ankle and foot
0.859 0.141 0.000
B35-B49 Mycoses
0.858 0.142 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.852 0.148 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.849 0.151 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.846 0.154 0.000
J93.9 Pneumothorax, unspecified
0.845 0.155 0.000
H90 Conductive and sensorineural hearing loss
0.843 0.157 0.000
M06.0 Seronegative rheumatoid arthritis
0.839 0.161 0.000
J30-J39 Other diseases of upper respiratory tract
0.839 0.161 0.000
O47 False labour
0.836 0.164 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.833 0.167 0.000
J86 Pyothorax
0.833 0.167 0.000
Y00-Y09 Assault
0.832 0.168 0.000
T79-T79 Certain early complications of trauma
0.832 0.168 0.000
M80-M85 Disorders of bone density and structure
0.831 0.169 0.000
S72 Fracture of femur
0.829 0.171 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.829 0.171 0.000
O36 Maternal care for other known or suspected foetal problems
0.828 0.172 0.000
S10-S19 Injuries to the neck
0.827 0.173 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.824 0.176 0.000
W50-W64 Exposure to animate mechanical forces
0.823 0.177 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.823 0.177 0.000
S50-S59 Injuries to the elbow and forearm
0.819 0.181 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.819 0.181 0.000
J38.7 Other diseases of larynx
0.817 0.183 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.816 0.184 0.000
O41 Other disorders of amniotic fluid and membranes
0.815 0.185 0.000
V20-V29 Motorcycle rider injured in transport accident
0.813 0.187 0.000
M05 Seropositive rheumatoid arthritis
0.811 0.189 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.808 0.192 0.000
Y45.0 Opioids and related analgesics
0.806 0.193 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.806 0.194 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.806 0.194 0.000
T66-T78 Other and unspecified effects of external causes
0.805 0.195 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.805 0.195 0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified
0.803 0.197 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.803 0.197 0.000
T85.4 Mechanical complication of breast prosthesis and implant
0.802 0.198 0.000
Y44 Agents primarily affecting blood constituents
0.801 0.199 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.799 0.201 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.797 0.203 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.796 0.204 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.795 0.205 0.000
S60-S69 Injuries to the wrist and hand
0.794 0.206 0.000
T92.1 Sequelae of fracture of arm
0.793 0.207 0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.793 0.207 0.000
G90-G99 Other disorders of the nervous system
0.791 0.208 0.000
M91-M94 Chondropathies
0.791 0.209 0.000
M89 Other disorders of bone
0.790 0.210 0.000
S70 Superficial injury of hip and thigh
0.789 0.211 0.000
W00-W19 Falls
0.789 0.211 0.000
B15-B19 Viral hepatitis
0.788 0.212 0.000
H43-H45 Disorders of vitreous body and globe
0.788 0.212 0.000
T86 Failure and rejection of transplanted organs and tissues
0.786 0.214 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.784 0.216 0.000
Y45.1 Salicylates
0.783 0.217 0.000
J86.9 Pyothorax without fistula
0.783 0.217 0.000
J18.9 Pneumonia, unspecified
0.782 0.218 0.000
Y95 Nosocomial condition
0.782 0.218 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.780 0.220 0.000
C73 Malignant neoplasm of thyroid gland
0.780 0.220 0.000
S22.4 Multiple fractures of ribs
0.779 0.221 0.000
S40-S49 Injuries to the shoulder and upper arm
0.777 0.223 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.776 0.224 0.000
M07 Psoriatic and enteropathic arthropathies
0.775 0.225 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.774 0.226 0.000
C50-C50 Malignant neoplasm of breast
0.774 0.226 0.000
Y57 Other and unspecified drugs and medicaments
0.774 0.226 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.773 0.227 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.772 0.228 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.770 0.230 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.769 0.231 0.000
J94 Other pleural conditions
0.769 0.231 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.768 0.232 0.000
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium
0.766 0.234 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.765 0.235 0.000
Chapter XXII Codes for special purposes
0.764 0.235 0.000
Y45.2 Propionic acid derivatives
0.764 0.236 0.000
C65 Malignant neoplasm of renal pelvis
0.764 0.236 0.000
A30-A49 Other bacterial diseases
0.764 0.236 0.000
O85-O92 Complications predominantly related to the puerperium
0.763 0.237 0.000
Q60-Q64 Congenital malformations of the urinary system
0.761 0.239 0.000
C80 Malignant neoplasm without specification of site
0.761 0.239 0.000
O80-O84 Delivery
0.760 0.240 0.000
O60-O75 Complications of labour and delivery
0.758 0.242 0.000
X60-X84 Intentional self-harm
0.758 0.242 0.000
B37 Candidiasis
0.758 0.242 0.000
B50-B64 Protozoal diseases
0.758 0.242 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.757 0.243 0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.756 0.244 0.000
T85.1 Mechanical complication of implanted electronic stimulator of nervous system
0.753 0.247 0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters
0.752 0.248 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.751 0.249 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.751 0.249 0.000
M14 Arthropathies in other diseases classified elsewhere
0.750 0.250 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.748 0.252 0.000
Y43 Primarily systemic agents
0.746 0.254 0.000
B65-B83 Helminthiases
0.745 0.255 0.000
Y40 Systemic antibiotics
0.744 0.256 0.000
H30-H36 Disorders of choroid and retina
0.744 0.256 0.000
M60-M63 Disorders of muscles
0.743 0.257 0.000
C79 Secondary malignant neoplasm of other sites
0.742 0.258 0.000
C51-C58 Malignant neoplasms of female genital organs
0.741 0.259 0.000
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium
0.740 0.260 0.000
G25 Other extrapyramidal and movement disorders
0.740 0.260 0.000
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters
0.738 0.262 0.000
H90.3 Sensorineural hearing loss, bilateral
0.737 0.263 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.735 0.265 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.735 0.265 0.000
T87 Complications peculiar to reattachment and amputation
0.731 0.268 0.000
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters
0.731 0.269 0.000
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters
0.731 0.269 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.730 0.270 0.000
S62 Fracture at wrist and hand level
0.730 0.270 0.000
Y83.5 Amputation of limb(s)
0.728 0.272 0.000
H02 Other disorders of eyelid
0.728 0.272 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.727 0.273 0.000
S22.40 Multiple fractures of ribs (closed)
0.727 0.273 0.000
J60-J70 Lung diseases due to external agents
0.727 0.273 0.000
O44 Placenta praevia
0.727 0.273 0.000
V10-V19 Pedal cyclist injured in transport accident
0.726 0.274 0.000
W20-W49 Exposure to inanimate mechanical forces
0.725 0.274 0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.725 0.275 0.000
D50-D53 Nutritional anaemias
0.725 0.275 0.000
G70-G73 Diseases of myoneural junction and muscle
0.723 0.277 0.000
Y83.8 Other surgical procedures
0.722 0.278 0.000
M89.9 Disorder of bone, unspecified
0.720 0.280 0.000
H35 Other retinal disorders
0.720 0.280 0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts
0.718 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.717 0.283 0.000
Y35-Y36 Legal intervention and operations of war
0.717 0.283 0.000
Y10-Y34 Event of undetermined intent
0.717 0.283 0.000
X85-X99 Assault
0.717 0.283 0.000
X50-X57 Overexertion, travel and privation
0.717 0.283 0.000
X30-X39 Exposure to forces of nature
0.717 0.283 0.000
X10-X19 Contact with heat and hot substances
0.717 0.283 0.000
X00-X09 Exposure to smoke, fire and flames
0.717 0.283 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.717 0.283 0.000
W75-W84 Other accidental threats to breathing
0.717 0.283 0.000
W65-W74 Accidental drowning and submersion
0.717 0.283 0.000
V98-V99 Other and unspecified transport accidents
0.717 0.283 0.000
V95-V97 Air and space transport accidents
0.717 0.283 0.000
V90-V94 Water transport accidents
0.717 0.283 0.000
V80-V89 Other land transport accidents
0.717 0.283 0.000
V70-V79 Bus occupant injured in transport accident
0.717 0.283 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.717 0.283 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.717 0.283 0.000
V40-V49 Car occupant injured in transport accident
0.717 0.283 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.717 0.283 0.000
V01-V09 Pedestrian injured in transport accident
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.716 0.284 0.000
S92 Fracture of foot, except ankle
0.716 0.284 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.715 0.285 0.000
M81 Osteoporosis without pathological fracture
0.715 0.285 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.711 0.289 0.000
Y04 Assault by bodily force
0.711 0.289 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.711 0.289 0.000
J10 Influenza due to identified influenza virus
0.710 0.289 0.000
B99-B99 Other infectious diseases
0.710 0.290 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.710 0.290 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.710 0.290 0.000
A75-A79 Rickettsioses
0.710 0.290 0.000
A70-A74 Other diseases caused by chlamydiae
0.710 0.290 0.000
A65-A69 Other spirochaetal diseases
0.710 0.290 0.000
A20-A28 Certain zoonotic bacterial diseases
0.710 0.290 0.000
A15-A19 Tuberculosis
0.710 0.290 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.709 0.291 0.000
Y59 Other and unspecified vaccines and biological substances
0.709 0.291 0.000
Y58 Bacterial vaccines
0.709 0.291 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.709 0.291 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.709 0.291 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.709 0.291 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.709 0.291 0.000
Y48 Anaesthetics and therapeutic gases
0.709 0.291 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.709 0.291 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.709 0.291 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.709 0.291 0.000
S51 Open wound of forearm
0.708 0.291 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.708 0.292 0.000
J17 Pneumonia in diseases classified elsewhere
0.708 0.292 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.708 0.292 0.000
J12 Viral pneumonia, not elsewhere classified
0.708 0.292 0.000
J09 Influenza due to certain identified influenza virus
0.708 0.292 0.000
O36.5 Maternal care for poor foetal growth
0.707 0.293 0.000
O45 Premature separation of placenta [abruptio placentae]
0.706 0.294 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.706 0.294 0.000
O33 Maternal care for known or suspected disproportion
0.706 0.294 0.000
O31 Complications specific to multiple gestation
0.706 0.294 0.000
O40 Polyhydramnios
0.706 0.294 0.000
C74 Malignant neoplasm of adrenal gland
0.706 0.294 0.000
C77.0 Lymph nodes of head, face and neck
0.706 0.294 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.704 0.296 0.000
X20-X29 Contact with venomous animals and plants
0.703 0.296 0.000
J95-J99 Other diseases of the respiratory system
0.703 0.297 0.000
G90 Disorders of autonomic nervous system
0.702 0.298 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.702 0.298 0.000
O42.2 Premature rupture of membranes, labour delayed by therapy
0.701 0.299 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.701 0.299 0.000
J11 Influenza, virus not identified
0.701 0.299 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.700 0.300 0.000
M06.3 Rheumatoid nodule
0.700 0.300 0.000
C77.1 Intrathoracic lymph nodes
0.699 0.301 0.000
Y52 Agents primarily affecting the cardiovascular system
0.699 0.301 0.000
B96.7 Clostridium perfringens [C. perfringens] as the cause of diseases classified to other chapters
0.698 0.302 0.000
B96.6 Bacillus fragilis [B. fragilis] as the cause of diseases classified to other chapters
0.698 0.302 0.000
B96.0 Mycoplasma pneumoniae [M. pneumoniae] as the cause of diseases classified to other chapters
0.698 0.302 0.000
J15.0 Pneumonia due to Klebsiella pneumoniae
0.698 0.302 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.697 0.303 0.000
H44 Disorders of globe
0.696 0.304 0.000
O43 Placental disorders
0.695 0.305 0.000
S72.2 Subtrochanteric fracture
0.693 0.307 0.000
H90.2 Conductive hearing loss, unspecified
0.692 0.308 0.000
M12 Other specific arthropathies
0.692 0.308 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.692 0.308 0.000
M08 Juvenile arthritis
0.692 0.308 0.000
S79 Other and unspecified injuries of hip and thigh
0.692 0.308 0.000
H01 Other inflammation of eyelid
0.691 0.309 0.000
D10-D36 Benign neoplasms
0.691 0.309 0.000
J14 Pneumonia due to Haemophilus influenzae
0.689 0.310 0.000
O47.0 False labour before 37 completed weeks of gestation
0.689 0.311 0.000
B37.0 Candidal stomatitis
0.689 0.311 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.688 0.312 0.000
M13 Other arthritis
0.686 0.314 0.000
M06.8 Other specified rheumatoid arthritis
0.685 0.314 0.000
M06.4 Inflammatory polyarthropathy
0.685 0.314 0.000
M06.2 Rheumatoid bursitis
0.685 0.314 0.000
M06.1 Adult-onset Still's disease
0.685 0.314 0.000
O36.9 Maternal care for foetal problem, unspecified
0.685 0.315 0.000
T92.2 Sequelae of fracture at wrist and hand level
0.684 0.316 0.000
G24 Dystonia
0.684 0.316 0.000
S62.6 Fracture of other finger
0.684 0.316 0.000
C66 Malignant neoplasm of ureter
0.681 0.319 0.000
T92.8 Sequelae of other specified injuries of upper limb
0.681 0.319 0.000
S20 Superficial injury of thorax
0.681 0.319 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.679 0.320 0.000
J39 Other diseases of upper respiratory tract
0.678 0.322 0.000
S22.3 Fracture of rib
0.678 0.322 0.000
Q61 Cystic kidney disease
0.678 0.322 0.000
A80-A89 Viral infections of the central nervous system
0.677 0.323 0.000
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified
0.677 0.323 0.000
Y45.8 Other analgesics and antipyretics
0.677 0.323 0.000
Y45.5 4-Aminophenol derivatives
0.677 0.323 0.000
Y45.4 Antirheumatics
0.677 0.323 0.000
H60-H62 Diseases of external ear
0.676 0.324 0.000
J30 Vasomotor and allergic rhinitis
0.676 0.324 0.000
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts
0.675 0.325 0.000
W06 Fall involving bed
0.675 0.325 0.000
T68 Hypothermia
0.675 0.325 0.000
S99 Other and unspecified injuries of ankle and foot
0.675 0.325 0.000
T92.3 Sequelae of dislocation, sprain and strain of upper limb
0.675 0.325 0.000
V27 Motorcycle rider injured in collision with fixed or stationary object
0.675 0.325 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.674 0.325 0.000
X59 Exposure to unspecified factor
0.674 0.326 0.000
T93 Sequelae of injuries of lower limb
0.673 0.327 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.673 0.327 0.000
M11 Other crystal arthropathies
0.673 0.327 0.000
H02.4 Ptosis of eyelid
0.673 0.327 0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts
0.672 0.328 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.672 0.328 0.000
T85.2 Mechanical complication of intraocular lens
0.671 0.329 0.000
M00-M03 Infectious arthropathies
0.671 0.329 0.000
M89.97 Disorder of bone, unspecified (Ankle and foot)
0.671 0.329 0.000
O72 Postpartum haemorrhage
0.670 0.330 0.000
C69 Malignant neoplasm of eye and adnexa
0.669 0.331 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.669 0.331 0.000
D45 Polycythaemia vera
0.668 0.332 0.000
S78 Traumatic amputation of hip and thigh
0.667 0.333 0.000
S77 Crushing injury of hip and thigh
0.667 0.333 0.000
S76 Injury of muscle and tendon at hip and thigh level
0.667 0.333 0.000
S75 Injury of blood vessels at hip and thigh level
0.667 0.333 0.000
S74 Injury of nerves at hip and thigh level
0.667 0.333 0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip
0.667 0.333 0.000
Y44.2 Anticoagulants
0.667 0.333 0.000
S71 Open wound of hip and thigh
0.667 0.333 0.000
O30 Multiple gestation
0.667 0.333 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.667 0.333 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.666 0.334 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.666 0.334 0.000
C68 Malignant neoplasm of other and unspecified urinary organs
0.666 0.334 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.665 0.335 0.000
T91 Sequelae of injuries of neck and trunk
0.665 0.335 0.000
J15.2 Pneumonia due to staphylococcus
0.665 0.335 0.000
H35.0 Background retinopathy and retinal vascular changes
0.665 0.335 0.000
G23 Other degenerative diseases of basal ganglia
0.663 0.337 0.000
G21 Secondary Parkinsonism
0.663 0.337 0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere
0.663 0.337 0.000
G22 Parkinsonism in diseases classified elsewhere
0.663 0.337 0.000
J18.8 Other pneumonia, organism unspecified
0.662 0.338 0.000
J18.2 Hypostatic pneumonia, unspecified
0.662 0.338 0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters
0.662 0.338 0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level
0.661 0.339 0.000
J38.5 Laryngeal spasm
0.661 0.339 0.000
T95 Sequelae of burns, corrosions and frostbite
0.660 0.339 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.660 0.339 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.660 0.339 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.660 0.339 0.000
S12 Fracture of neck
0.660 0.339 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.660 0.340 0.000
T98 Sequelae of other and unspecified effects of external causes
0.660 0.340 0.000
J93.8 Other pneumothorax
0.660 0.340 0.000
T85.9 Unspecified complication of internal prosthetic device, implant and graft
0.659 0.340 0.000
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt
0.659 0.340 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.659 0.341 0.000
T13 Other injuries of lower limb, level unspecified
0.659 0.341 0.000
M82 Osteoporosis in diseases classified elsewhere
0.658 0.342 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.658 0.342 0.000
S72.3 Fracture of shaft of femur
0.658 0.342 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.657 0.343 0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified
0.657 0.343 0.000
H94 Other disorders of ear in diseases classified elsewhere
0.657 0.343 0.000
T84.3 Mechanical complication of other bone devices, implants and grafts
0.656 0.344 0.000
M85 Other disorders of bone density and structure
0.656 0.344 0.000
H35.9 Retinal disorder, unspecified
0.655 0.345 0.000
Y41.0 Sulphonamides
0.654 0.346 0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax
0.654 0.346 0.000
S26 Injury of heart
0.654 0.346 0.000
S25 Injury of blood vessels of thorax
0.654 0.346 0.000
S24 Injury of nerves and spinal cord at thorax level
0.654 0.346 0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax
0.654 0.346 0.000
S21 Open wound of thorax
0.654 0.346 0.000
T81 Complications of procedures, not elsewhere classified
0.654 0.346 0.000
J15.1 Pneumonia due to Pseudomonas
0.654 0.346 0.000
S27 Injury of other and unspecified intrathoracic organs
0.653 0.346 0.000
S72.0 Fracture of neck of femur
0.653 0.347 0.000
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.652 0.347 0.000
O97 Death from sequelae of direct obstetric causes
0.652 0.347 0.000
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery
0.652 0.347 0.000
O95 Obstetric death of unspecified cause
0.652 0.347 0.000
O94 Sequelae of complication of pregnancy, childbirth and the puerperium
0.652 0.347 0.000
M45-M49 Spondylopathies
0.652 0.348 0.000
H55-H59 Other disorders of eye and adnexa
0.652 0.348 0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts
0.652 0.348 0.000
Y85 Sequelae of transport accidents
0.652 0.348 0.000
G95 Other diseases of spinal cord
0.651 0.349 0.000
W51 Striking against or bumped into by another person
0.651 0.349 0.000
B97.7 Papillomavirus as the cause of diseases classified to other chapters
0.651 0.349 0.000
M65-M68 Disorders of synovium and tendon
0.649 0.350 0.000
O41.0 Oligohydramnios
0.649 0.351 0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft
0.649 0.351 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.649 0.351 0.000
H91.8 Other specified hearing loss
0.649 0.351 0.000
H91.3 Deaf mutism, not elsewhere classified
0.649 0.351 0.000
H91.2 Sudden idiopathic hearing loss
0.649 0.351 0.000
H91.1 Presbycusis
0.649 0.351 0.000
H91.0 Ototoxic hearing loss
0.649 0.351 0.000
O24 Diabetes mellitus in pregnancy
0.648 0.351 0.000
Q00-Q07 Congenital malformations of the nervous system
0.648 0.352 0.000
H43 Disorders of vitreous body
0.648 0.352 0.000
J85 Abscess of lung and mediastinum
0.647 0.353 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.647 0.353 0.000
M40-M43 Deforming dorsopathies
0.647 0.353 0.000
D70 Agranulocytosis
0.646 0.354 0.000
Q80-Q89 Other congenital malformations
0.645 0.355 0.000
Q50-Q56 Congenital malformations of genital organs
0.645 0.355 0.000
O41.8 Other specified disorders of amniotic fluid and membranes
0.645 0.355 0.000
S70.1 Contusion of thigh
0.644 0.356 0.000
Y57.8 Other drugs and medicaments
0.644 0.356 0.000
J31.0 Chronic rhinitis
0.644 0.356 0.000
J93.0 Spontaneous tension pneumothorax
0.643 0.357 0.000
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters
0.643 0.357 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.643 0.357 0.000
O42.0 Premature rupture of membranes, onset of labour within 24 hours
0.643 0.357 0.000
H90.4 Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
0.641 0.359 0.000
S72.1 Pertrochanteric fracture
0.641 0.359 0.000
O47.9 False labour, unspecified
0.641 0.359 0.000
C43 Malignant melanoma of skin
0.641 0.359 0.000
G62 Other polyneuropathies
0.640 0.360 0.000
G60 Hereditary and idiopathic neuropathy
0.639 0.361 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.639 0.361 0.000
M07.3 Other psoriatic arthropathies
0.639 0.361 0.000
T86.1 Kidney transplant failure and rejection
0.638 0.361 0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts
0.638 0.362 0.000
B15 Acute hepatitis A
0.638 0.362 0.000
Y42.0 Glucocorticoids and synthetic analogs
0.637 0.363 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.636 0.364 0.000
M94 Other disorders of cartilage
0.635 0.364 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.634 0.366 0.000
C75 Malignant neoplasm of other endocrine glands and related structures
0.634 0.366 0.000
B49 Unspecified mycosis
0.634 0.366 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.634 0.366 0.000
Q35-Q37 Cleft lip and cleft palate
0.634 0.366 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.634 0.366 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.634 0.366 0.000
G80 Infantile cerebral palsy
0.634 0.366 0.000
G91 Hydrocephalus
0.634 0.366 0.000
S70.9 Superficial injury of hip and thigh, unspecified
0.633 0.367 0.000
S22.1 Multiple fractures of thoracic spine
0.632 0.368 0.000
O23 Infections of genito-urinary tract in pregnancy
0.632 0.368 0.000
S62.60 Fracture of other finger (closed)
0.632 0.368 0.000
G83 Other paralytic syndromes
0.631 0.369 0.000
Y83.9 Surgical procedure, unspecified
0.630 0.370 0.000
Y83.0 Surgical operation with transplant of whole organ
0.630 0.370 0.000
B35 Dermatophytosis
0.630 0.370 0.000
W18 Other fall on same level
0.629 0.370 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.629 0.371 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.629 0.371 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.628 0.372 0.000
S22.0 Fracture of thoracic vertebra
0.628 0.372 0.000
X58 Exposure to other specified factors
0.628 0.372 0.000
H44.2 Degenerative myopia
0.628 0.372 0.000
T80.8 Other complications following infusion, transfusion and therapeutic injection
0.627 0.373 0.000
O47.1 False labour at or after 37 completed weeks of gestation
0.627 0.373 0.000
D80-D89 Certain disorders involving the immune mechanism
0.626 0.373 0.000
W55 Bitten or struck by other mammals
0.626 0.373 0.000
Q61.0 Congenital single renal cyst
0.626 0.374 0.000
H10-H13 Disorders of conjunctiva
0.626 0.374 0.000
D50 Iron deficiency anaemia
0.626 0.374 0.000
Y91 Evidence of alcohol involvement determined by level of intoxication
0.626 0.374 0.000
Y90 Evidence of alcohol involvement determined by blood alcohol level
0.626 0.374 0.000
Y98 Lifestyle-related condition
0.626 0.374 0.000
Y97 Environmental-pollution-related condition
0.626 0.374 0.000
Y96 Work-related condition
0.626 0.374 0.000
D23 Other benign neoplasms of skin
0.625 0.375 0.000
Y83.3 Surgical operation with formation of external stoma
0.625 0.375 0.000
D55-D59 Haemolytic anaemias
0.625 0.375 0.000
Y04.8 Other specified place
0.625 0.375 0.000
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters
0.625 0.375 0.000
T92.0 Sequelae of open wound of upper limb
0.625 0.375 0.000
T92.9 Sequelae of unspecified injury of upper limb
0.624 0.375 0.000
T92.6 Sequelae of crushing injury and traumatic amputation of upper limb
0.624 0.375 0.000
T92.5 Sequelae of injury of muscle and tendon of upper limb
0.624 0.375 0.000
T92.4 Sequelae of injury of nerve of upper limb
0.624 0.375 0.000
M89.8 Other specified disorders of bone
0.624 0.376 0.000
B97.8 Other viral agents as the cause of diseases classified to other chapters
0.623 0.377 0.000
C79.2 Secondary malignant neoplasm of skin
0.623 0.377 0.000
T23 Burn and corrosion of wrist and hand
0.623 0.377 0.000
D26 Other benign neoplasms of uterus
0.622 0.378 0.000
S91 Open wound of ankle and foot
0.620 0.379 0.000
C71 Malignant neoplasm of brain
0.620 0.379 0.000
D72 Other disorders of white blood cells
0.620 0.380 0.000
Y89 Sequelae of other external causes
0.620 0.380 0.000
W50 Hit, struck, kicked, twisted, bitten or scratched by another person
0.620 0.380 0.000
D47.3 Essential (haemorrhagic) thrombocythaemia
0.619 0.381 0.000
C50 Malignant neoplasm of breast
0.619 0.381 0.000
S29 Other and unspecified injuries of thorax
0.619 0.381 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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