TreeWAS – Variant ID: rs11191416

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I20-I25 Ischaemic heart diseases	0.000	0.000	1.000
I25 Chronic ischaemic heart disease	0.000	0.000	1.000
I20 Angina pectoris	0.000	0.000	1.000
I20.0 Unstable angina	0.000	0.000	1.000
I20.9 Angina pectoris, unspecified	0.000	0.008	0.992
I10 Essential (primary) hypertension	0.000	0.010	0.990
I25.8 Other forms of chronic ischaemic heart disease	0.000	0.013	0.987
I25.2 Old myocardial infarction	0.000	0.017	0.983
I25.1 Atherosclerotic heart disease	0.000	0.020	0.980
I24 Other acute ischaemic heart diseases	0.000	0.025	0.975
I10-I15 Hypertensive diseases	0.000	0.045	0.955
Chapter IX Diseases of the circulatory system	0.000	0.064	0.936
I21 Acute myocardial infarction	0.000	0.073	0.927
I25.9 Chronic ischaemic heart disease, unspecified	0.000	0.085	0.915
I22 Subsequent myocardial infarction	0.000	0.098	0.902
I21.4 Acute subendocardial myocardial infarction	0.000	0.113	0.887
I24.9 Acute ischaemic heart disease, unspecified	0.000	0.114	0.886
I24.8 Other forms of acute ischaemic heart disease	0.000	0.121	0.879
I60-I69 Cerebrovascular diseases	0.000	0.126	0.874
I69 Sequelae of cerebrovascular disease	0.000	0.167	0.833
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.000	0.180	0.820
I21.0 Acute transmural myocardial infarction of anterior wall	0.000	0.183	0.817
I20.1 Angina pectoris with documented spasm	0.000	0.204	0.796
I15 Secondary hypertension	0.000	0.210	0.790
I25.4 Coronary artery aneurysm	0.000	0.219	0.781
I22.9 Subsequent myocardial infarction of unspecified site	0.000	0.224	0.776
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.000	0.233	0.767
I64 Stroke, not specified as haemorrhage or infarction	0.000	0.250	0.750
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.000	0.250	0.750
I22.1 Subsequent myocardial infarction of inferior wall	0.000	0.280	0.720
I25.6 Silent myocardial ischaemia	0.000	0.283	0.717
I25.0 Atherosclerotic cardiovascular disease, so described	0.000	0.283	0.717
I25.3 Aneurysm of heart	0.000	0.294	0.706
I62 Other nontraumatic intracranial haemorrhage	0.000	0.298	0.702
I24.1 Dressler's syndrome	0.000	0.301	0.699
I22.8 Subsequent myocardial infarction of other sites	0.000	0.301	0.699
I25.5 Ischaemic cardiomyopathy	0.000	0.303	0.697
I69.3 Sequelae of cerebral infarction	0.000	0.308	0.692
I13 Hypertensive heart and renal disease	0.000	0.315	0.685
I65.2 Occlusion and stenosis of carotid artery	0.000	0.318	0.682
I00-I02 Acute rheumatic fever	0.000	0.329	0.671
I15.1 Hypertension secondary to other renal disorders	0.000	0.329	0.671
I21.X Presumed acute myicardial infaction (unconfirmed)	0.000	0.335	0.665
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.000	0.337	0.663
I21.3 Acute transmural myocardial infarction of unspecified site	0.000	0.342	0.657
I22.0 Subsequent myocardial infarction of anterior wall	0.000	0.344	0.656
I69.1 Sequelae of intracerebral haemorrhage	0.000	0.344	0.656
I23 Certain current complications following acute myocardial infarction	0.000	0.347	0.653
I21.2 Acute transmural myocardial infarction of other sites	0.000	0.368	0.632
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.000	0.373	0.627
I60 Subarachnoid haemorrhage	0.000	0.383	0.617
I63 Cerebral infarction	0.000	0.397	0.603
I11 Hypertensive heart disease	0.000	0.399	0.601
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.000	0.403	0.597
I15.9 Seconday hypertension, unspecified	0.000	0.434	0.566
I15.8 Other secondary hypertension	0.000	0.434	0.566
I15.2 Hypertension secondary to endocrine disorders	0.000	0.434	0.566
I15.0 Renovascular hypertension	0.000	0.434	0.566
I21.1 Acute transmural myocardial infarction of inferior wall	0.000	0.440	0.560
I68 Cerebrovascular disorders in diseases classified elsewhere	0.000	0.443	0.557
I62.9 Intracranial haemorrhage (nontraumatic), unspecified	0.000	0.450	0.550
I62.0 Subdural haemorrhage (acute) (nontraumatic)	0.000	0.460	0.540
I65.9 Occlusion and stenosis of unspecified precerebral artery	0.000	0.462	0.538
I65.8 Occlusion and stenosis of other precerebral artery	0.000	0.462	0.538
I65.1 Occlusion and stenosis of basilar artery	0.000	0.462	0.538
I65.0 Occlusion and stenosis of vertebral artery	0.000	0.462	0.538
I12 Hypertensive renal disease	0.000	0.482	0.518
I69.0 Sequelae of subarachnoid haemorrhage	0.000	0.491	0.509
I62.1 Nontraumatic extradural haemorrhage	0.000	0.497	0.503
I67 Other cerebrovascular diseases	0.000	0.497	0.503
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.000	0.501	0.499
I63.3 Cerebral infarction due to thrombosis of cerebral arteries	0.000	0.508	0.492
I13.9 Hypertensive heart and renal disease, unspecified	0.000	0.509	0.491
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure	0.000	0.509	0.491
I13.1 Hypertensive heart and renal disease with renal failure	0.000	0.509	0.491
I13.0 Hypertensive heart and renal disease with (congestive) heart failure	0.000	0.509	0.491
I60.8 Other subarachnoid haemorrhage	0.000	0.516	0.483
I02 Rheumatic chorea	0.000	0.519	0.481
I01 Rheumatic fever with heart involvement	0.000	0.519	0.481
I00 Rheumatic fever without mention of heart involvement	0.000	0.519	0.481
I60.3 Subarachnoid haemorrhage from posterior communicating artery	0.000	0.523	0.477
I60.1 Subarachnoid haemorrhage from middle cerebral artery	0.000	0.524	0.476
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries	0.000	0.525	0.475
I63.4 Cerebral infarction due to embolism of cerebral arteries	0.000	0.530	0.470
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction	0.000	0.532	0.468
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction	0.000	0.532	0.468
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction	0.000	0.532	0.468
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction	0.000	0.532	0.468
I23.2 Ventricular septal defect as current complication following acute myocardial infarction	0.000	0.532	0.468
I23.1 Atrial septal defect as current complication following acute myocardial infarction	0.000	0.532	0.468
I23.0 Haemopericardium as current complication following acute myocardial infarction	0.000	0.532	0.468
I95-I99 Other and unspecified disorders of the circulatory system	0.000	0.535	0.465
I66.9 Occlusion and stenosis of unspecified cerebral artery	0.000	0.550	0.449
I66.8 Occlusion and stenosis of other cerebral artery	0.000	0.550	0.449
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries	0.000	0.550	0.449
I66.3 Occlusion and stenosis of cerebellar arteries	0.000	0.550	0.449
I66.2 Occlusion and stenosis of posterior cerebral artery	0.000	0.550	0.449
I66.1 Occlusion and stenosis of anterior cerebral artery	0.000	0.550	0.449
I66.0 Occlusion and stenosis of middle cerebral artery	0.000	0.550	0.449
I67.1 Cerebral aneurysm, nonruptured	0.000	0.551	0.449
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified	0.000	0.558	0.442
I60.6 Subarachnoid haemorrhage from other intracranial arteries	0.000	0.558	0.442
I60.5 Subarachnoid haemorrhage from vertebral artery	0.000	0.558	0.442
I60.4 Subarachnoid haemorrhage from basilar artery	0.000	0.558	0.442
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation	0.000	0.558	0.442
I63.8 Other cerebral infarction	0.000	0.563	0.437
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic	0.000	0.567	0.432
I63.1 Cerebral infarction due to embolism of precerebral arteries	0.000	0.567	0.432
I63.0 Cerebral infarction due to thrombosis of precerebral arteries	0.000	0.567	0.432
I21.9 Acute myocardial infarction, unspecified	0.000	0.568	0.432
I11.9 Hypertensive heart disease without (congestive) heart failure	0.000	0.589	0.411
I23.8 Other current complications following acute myocardial infarction	0.000	0.595	0.404
I68.8 Other cerebrovascular disorders in diseases classified elsewhere	0.000	0.600	0.400
I68.2 Cerebral arteritis in other diseases classified elsewhere	0.000	0.600	0.400
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere	0.000	0.600	0.400
I60.2 Subarachnoid haemorrhage from anterior communicating artery	0.000	0.607	0.393
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.000	0.610	0.389
I99 Other and unspecified disorders of circulatory system	0.000	0.625	0.375
I11.0 Hypertensive heart disease with (congestive) heart failure	0.000	0.625	0.374
I12.9 Hypertensive renal disease without renal failure	0.000	0.629	0.371
I67.2 Cerebral atherosclerosis	0.000	0.631	0.368
I67.7 Cerebral arteritis, not elsewhere classified	0.000	0.639	0.361
I67.6 Nonpyogenic thrombosis of intracranial venous system	0.000	0.639	0.361
I67.5 Moyamoya disease	0.000	0.639	0.361
I67.4 Hypertensive encephalopathy	0.000	0.639	0.361
I67.3 Progressive vascular leukoencephalopathy	0.000	0.639	0.361
I67.0 Dissection of cerebral arteries, nonruptured	0.000	0.639	0.361
I98 Other disorders of circulatory system in diseases classified elsewhere	0.000	0.646	0.354
I01.9 Acute rheumatic heart disease, unspecified	0.000	0.655	0.345
I01.8 Other acute rheumatic heart disease	0.000	0.655	0.345
I01.2 Acute rheumatic myocarditis	0.000	0.655	0.345
I01.1 Acute rheumatic endocarditis	0.000	0.655	0.345
I01.0 Acute rheumatic pericarditis	0.000	0.655	0.345
I02.9 Rheumatic chorea without heart involvement	0.000	0.655	0.345
I02.0 Rheumatic chorea with heart involvement	0.000	0.655	0.345
I68.0 Cerebral amyloid angiopathy	0.001	0.669	0.330
I60.9 Subarachnoid haemorrhage, unspecified	0.000	0.675	0.325
I05-I09 Chronic rheumatic heart diseases	0.000	0.707	0.293
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.001	0.712	0.288
I98.2 Oesophageal varices in diseases classified elsewhere	0.000	0.717	0.282
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.000	0.727	0.272
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere	0.000	0.746	0.254
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere	0.000	0.746	0.254
I98.0 Cardiovascular syphilis	0.000	0.746	0.254
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere	0.000	0.756	0.243
I70-I79 Diseases of arteries, arterioles and capillaries	0.000	0.761	0.239
I20.8 Other forms of angina pectoris	0.000	0.775	0.225
I97.2 Postmastectomy lymphoedema syndrome	0.000	0.782	0.218
I09 Other rheumatic heart diseases	0.000	0.789	0.210
I06 Rheumatic aortic valve diseases	0.000	0.789	0.210
I12.0 Hypertensive renal disease with renal failure	0.000	0.795	0.205
I67.8 Other specified cerebrovascular diseases	0.000	0.795	0.205
I77 Other disorders of arteries and arterioles	0.000	0.797	0.203
I97.9 Postprocedural disorder of circulatory system, unspecified	0.000	0.804	0.195
I97.0 Postcardiotomy syndrome	0.000	0.804	0.195
I07 Rheumatic tricuspid valve diseases	0.000	0.805	0.195
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.000	0.811	0.189
I77.1 Stricture of artery	0.000	0.815	0.185
I28 Other diseases of pulmonary vessels	0.001	0.820	0.180
I61 Intracerebral haemorrhage	0.003	0.824	0.173
I71 Aortic aneurysm and dissection	0.000	0.832	0.168
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified	0.001	0.842	0.157
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.000	0.846	0.154
I70 Atherosclerosis	0.000	0.847	0.153
I05 Rheumatic mitral valve diseases	0.001	0.849	0.151
I06.9 Rheumatic aortic valve disease, unspecified	0.000	0.849	0.151
I06.8 Other rheumatic aortic valve diseases	0.000	0.849	0.151
I06.2 Rheumatic aortic stenosis with insufficiency	0.000	0.849	0.151
I06.1 Rheumatic aortic insufficiency	0.000	0.849	0.151
I06.0 Rheumatic aortic stenosis	0.000	0.849	0.151
I09.9 Rheumatic heart disease, unspecified	0.000	0.849	0.151
I09.8 Other specified rheumatic heart diseases	0.000	0.849	0.151
I09.2 Chronic rheumatic pericarditis	0.000	0.849	0.151
I09.1 Rheumatic diseases of endocardium, valve unspecified	0.000	0.849	0.151
I09.0 Rheumatic myocarditis	0.000	0.849	0.151
I67.9 Cerebrovascular disease, unspecified	0.000	0.850	0.150
I77.6 Arteritis, unspecified	0.000	0.850	0.150
I77.9 Disorder of arteries and arterioles, unspecified	0.000	0.853	0.147
I78 Diseases of capillaries	0.000	0.853	0.147
Z95.5 Presence of coronary angioplasty implant and graft	0.000	0.854	0.146
I77.5 Necrosis of artery	0.000	0.854	0.146
I77.4 Coeliac artery compression syndrome	0.000	0.854	0.146
I77.3 Arterial fibromuscular dysplasia	0.000	0.854	0.146
I77.2 Rupture of artery	0.000	0.854	0.146
I97.1 Other functional disturbances following cardiac surgery	0.001	0.857	0.142
I07.9 Tricuspid valve disease, unspecified	0.000	0.860	0.140
I07.8 Other tricuspid valve diseases	0.000	0.860	0.140
I07.2 Tricuspid stenosis with insufficiency	0.000	0.860	0.140
I07.0 Tricuspid stenosis	0.000	0.860	0.140
I71.0 Dissection of aorta [any part]	0.000	0.862	0.138
I27 Other pulmonary heart diseases	0.001	0.862	0.137
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.000	0.864	0.136
I79.1 Aortitis in diseases classified elsewhere	0.000	0.864	0.136
I79.0 Aneurysm of aorta in diseases classified elsewhere	0.000	0.864	0.136
I77.8 Other specified disorders of arteries and arterioles	0.000	0.865	0.135
I77.0 Arteriovenous fistula, acquired	0.000	0.870	0.130
I28.9 Disease of pulmonary vessels, unspecified	0.001	0.870	0.129
I28.1 Aneurysm of pulmonary artery	0.001	0.870	0.129
I28.0 Arteriovenous fistula of pulmonary vessels	0.001	0.870	0.129
I61.5 Intracerebral haemorrhage, intraventricular	0.002	0.871	0.127
I61.2 Intracerebral haemorrhage in hemisphere, unspecified	0.002	0.872	0.126
I61.6 Intracerebral haemorrhage, multiple localised	0.002	0.874	0.124
Z95 Presence of cardiac and vascular implants and grafts	0.000	0.874	0.126
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.000	0.875	0.125
I71.3 Abdominal aortic aneurysm, ruptured	0.000	0.875	0.125
I07.1 Tricuspid insufficiency	0.000	0.876	0.124
Z95.8 Presence of other cardiac and vascular implants and grafts	0.000	0.876	0.124
I74 Arterial embolism and thrombosis	0.000	0.879	0.121
I71.8 Aortic aneurysm of unspecified site, ruptured	0.000	0.879	0.121
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.000	0.879	0.121
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.000	0.879	0.121
I71.1 Thoracic aortic aneurysm, ruptured	0.000	0.879	0.121
I61.0 Intracerebral haemorrhage in hemisphere, subcortical	0.002	0.881	0.117
I61.3 Intracerebral haemorrhage in brain stem	0.002	0.881	0.116
I61.8 Other intracerebral haemorrhage	0.002	0.884	0.114
I05.1 Rheumatic mitral insufficiency	0.000	0.885	0.115
Z95.2 Presence of prosthetic heart valve	0.000	0.889	0.111
I70.9 Generalised and unspecified atherosclerosis	0.000	0.890	0.110
I70.8 Atherosclerosis of other arteries	0.000	0.890	0.110
I05.8 Other mitral valve diseases	0.001	0.891	0.108
I70.1 Atherosclerosis of renal artery	0.000	0.892	0.108
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.000	0.892	0.108
I78.9 Disease of capillaries, unspecified	0.000	0.895	0.105
I27.0 Primary pulmonary hypertension	0.000	0.895	0.105
I70.0 Atherosclerosis of aorta	0.000	0.895	0.104
I78.0 Hereditary haemorrhagic telangiectasia	0.000	0.896	0.104
I28.8 Other specified diseases of pulmonary vessels	0.001	0.897	0.102
I61.4 Intracerebral haemorrhage in cerebellum	0.002	0.897	0.100
I27.8 Other specified pulmonary heart diseases	0.000	0.898	0.102
I78.8 Other diseases of capillaries	0.000	0.899	0.101
I70.2 Atherosclerosis of arteries of the extremities	0.000	0.900	0.100
I27.1 Kyphoscoliotic heart disease	0.001	0.901	0.099
I26 Pulmonary embolism	0.001	0.901	0.099
I05.9 Mitral valve disease, unspecified	0.001	0.902	0.097
I72 Other aneurysm	0.000	0.903	0.097
Z95.3 Presence of xenogenic heart valve	0.000	0.904	0.096
I74.5 Embolism and thrombosis of iliac artery	0.000	0.906	0.094
I63.9 Cerebral infarction, unspecified	0.000	0.909	0.091
I05.2 Mitral stenosis with insufficiency	0.001	0.909	0.091
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.000	0.909	0.091
Z95.9 Presence of cardiac and vascular implant and graft, unspecified	0.000	0.910	0.090
I61.1 Intracerebral haemorrhage in hemisphere, cortical	0.003	0.910	0.087
I78.1 Naevus, nonneoplastic	0.000	0.911	0.089
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.000	0.913	0.087
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.000	0.913	0.087
I74.0 Embolism and thrombosis of abdominal aorta	0.000	0.913	0.087
I74.8 Embolism and thrombosis of other arteries	0.000	0.915	0.085
I05.0 Mitral stenosis	0.001	0.917	0.082
Z95.4 Presence of other heart-valve replacement	0.000	0.917	0.082
I27.9 Pulmonary heart disease, unspecified	0.001	0.918	0.081
I70.81 Atherosclerosis of other arteries (with gangrene)	0.000	0.921	0.079
I70.80 Atherosclerosis of other arteries (without gangrene)	0.000	0.921	0.079
I70.91 Generalized and unspecified atherosclerosis (with gangrene)	0.000	0.921	0.079
I70.90 Generalized and unspecified atherosclerosis (without gangrene)	0.000	0.921	0.079
Z95.0 Presence of cardiac pacemaker	0.000	0.921	0.079
I72.0 Aneurysm of carotid artery	0.000	0.922	0.078
I70.11 Atherosclerosis of renal artery (with gangrene)	0.000	0.922	0.077
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.000	0.923	0.076
I70.10 Atherosclerosis of renal artery (without gangrene)	0.000	0.924	0.075
I70.01 Atherosclerosis of aorta (with gangrene)	0.000	0.925	0.075
I70.21 Atherosclerosis of arteries of extremities (with gangrene)	0.000	0.928	0.072
I74.9 Embolism and thrombosis of unspecified artery	0.000	0.928	0.072
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.000	0.930	0.070
I70.00 Atherosclerosis of aorta (without gangrene)	0.000	0.930	0.070
I72.6 Aneurysm and dissection of vertebral artery	0.000	0.930	0.069
I72.5 Aneurysm and dissection of other precerebral arteries	0.000	0.930	0.069
I72.1 Aneurysm of artery of upper extremity	0.000	0.930	0.069
I72.8 Aneurysm of other specified arteries	0.000	0.932	0.067
I08 Multiple valve diseases	0.001	0.933	0.066
I72.2 Aneurysm of renal artery	0.000	0.935	0.065
I30-I52 Other forms of heart disease	0.000	0.937	0.063
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.000	0.937	0.062
I95 Hypotension	0.001	0.939	0.061
I72.9 Aneurysm of unspecified site	0.000	0.939	0.060
I26.0 Pulmonary embolism with mention of acute cor pulmonale	0.001	0.941	0.059
I50 Heart failure	0.000	0.941	0.059
I44 Atrioventricular and left bundle-branch block	0.000	0.941	0.059
I50.1 Left ventricular failure	0.000	0.943	0.057
I45 Other conduction disorders	0.000	0.943	0.057
I44.1 Atrioventricular block, second degree	0.000	0.946	0.054
I44.7 Left bundle-branch block, unspecified	0.000	0.946	0.054
I08.2 Disorders of both aortic and tricuspid valves	0.000	0.947	0.052
I45.1 Other and unspecified right bundle-branch block	0.000	0.948	0.052
I72.4 Aneurysm of artery of lower extremity	0.001	0.950	0.049
I08.9 Multiple valve disease, unspecified	0.001	0.952	0.048
I72.3 Aneurysm of iliac artery	0.001	0.952	0.047
I73 Other peripheral vascular diseases	0.000	0.952	0.047
I45.6 Preexcitation syndrome	0.000	0.954	0.046
I46 Cardiac arrest	0.000	0.954	0.046
I45.2 Bifascicular block	0.000	0.954	0.046
Z95.1 Presence of aortocoronary bypass graft	0.000	0.954	0.046
I52 Other heart disorders in diseases classified elsewhere	0.000	0.954	0.045
I48 Atrial fibrillation and flutter	0.000	0.954	0.045
I43 Cardiomyopathy in diseases classified elsewhere	0.000	0.954	0.045
I41 Myocarditis in diseases classified elsewhere	0.000	0.954	0.045
I40 Acute myocarditis	0.000	0.954	0.045
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.000	0.954	0.045
I32 Pericarditis in diseases classified elsewhere	0.000	0.954	0.045
I44.0 Atrioventricular block, first degree	0.000	0.954	0.046
I95.8 Other hypotension	0.001	0.956	0.044
I95.0 Idiopathic hypotension	0.001	0.956	0.044
I44.6 Other and unspecified fascicular block	0.000	0.956	0.044
I50.0 Congestive heart failure	0.000	0.956	0.044
I36 Nonrheumatic tricuspid valve disorders	0.000	0.956	0.044
I27.2 Other secondary pulmonary hypertension	0.001	0.957	0.042
I37 Pulmonary valve disorders	0.000	0.957	0.042
I45.4 Nonspecific intraventricular block	0.000	0.958	0.042
I45.3 Trifascicular block	0.000	0.958	0.042
I33 Acute and subacute endocarditis	0.000	0.958	0.042
I44.5 Left posterior fascicular block	0.000	0.958	0.042
I61.9 Intracerebral haemorrhage, unspecified	0.003	0.958	0.039
I45.0 Right fascicular block	0.000	0.959	0.041
I08.8 Other multiple valve diseases	0.001	0.959	0.040
I45.8 Other specified conduction disorders	0.000	0.960	0.040
I08.1 Disorders of both mitral and tricuspid valves	0.000	0.960	0.039
I44.3 Other and unspecified atrioventricular block	0.000	0.961	0.039
I45.5 Other specified heart block	0.000	0.964	0.036
R07.4 Chest pain, unspecified	0.000	0.964	0.036
I46.0 Cardiac arrest with successful resuscitation	0.000	0.964	0.036
I50.9 Heart failure, unspecified	0.000	0.964	0.036
I73.1 Thromboangiitis obliterans [Buerger]	0.000	0.966	0.034
I30 Acute pericarditis	0.000	0.966	0.034
I35 Nonrheumatic aortic valve disorders	0.000	0.966	0.034
I46.1 Sudden cardiac death, so described	0.000	0.967	0.033
I31 Other diseases of pericardium	0.000	0.967	0.033
I32.8 Pericarditis in other diseases classified elsewhere	0.000	0.967	0.033
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere	0.000	0.967	0.033
I32.0 Pericarditis in bacterial diseases classified elsewhere	0.000	0.967	0.033
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere	0.000	0.967	0.033
I39.4 Multiple valve disorders in diseases classified elsewhere	0.000	0.967	0.033
I39.3 Pulmonary valve disorders in diseases classified elsewhere	0.000	0.967	0.033
I39.2 Tricuspid valve disorders in diseases classified elsewhere	0.000	0.967	0.033
I39.1 Aortic valve disorders in diseases classified elsewhere	0.000	0.967	0.033
I39.0 Mitral valve disorders in diseases classified elsewhere	0.000	0.967	0.033
I40.9 Acute myocarditis, unspecified	0.000	0.967	0.033
I40.8 Other acute myocarditis	0.000	0.967	0.033
I40.1 Isolated myocarditis	0.000	0.967	0.033
I40.0 Infective myocarditis	0.000	0.967	0.033
I41.8 Myocarditis in other diseases classified elsewhere	0.000	0.967	0.033
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere	0.000	0.967	0.033
I41.1 Myocarditis in viral diseases classified elsewhere	0.000	0.967	0.033
I41.0 Myocarditis in bacterial diseases classified elsewhere	0.000	0.967	0.033
I43.8 Cardiomyopathy in other diseases classified elsewhere	0.000	0.967	0.033
I43.2 Cardiomyopathy in nutritional diseases	0.000	0.967	0.033
I43.1 Cardiomyopathy in metabolic diseases	0.000	0.967	0.033
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere	0.000	0.967	0.033
I48.9 Atrial fibrillation and atrial flutter, unspecified	0.000	0.967	0.033
I48.4 Atypical atrial flutter	0.000	0.967	0.033
I48.3 Typical atrial flutter	0.000	0.967	0.033
I48.2 Chronic atrial fibrillation	0.000	0.967	0.033
I48.1 Persistent atrial fibrillation	0.000	0.967	0.033
I48.0 Paroxysmal atrial fibrillation	0.000	0.967	0.033
I52.8 Other heart disorders in other diseases classified elsewhere	0.000	0.967	0.033
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere	0.000	0.967	0.033
I52.0 Other heart disorders in bacterial diseases classified elsewhere	0.000	0.967	0.033
I45.9 Conduction disorder, unspecified	0.000	0.967	0.033
I73.8 Other specified peripheral vascular diseases	0.000	0.967	0.033
I95.2 Hypotension due to drugs	0.001	0.967	0.032
I44.4 Left anterior fascicular block	0.000	0.968	0.032
I44.2 Atrioventricular block, complete	0.000	0.968	0.032
I36.9 Nonrheumatic tricuspid valve disorder, unspecified	0.000	0.968	0.031
I36.8 Other nonrheumatic tricuspid valve disorders	0.000	0.968	0.031
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency	0.000	0.968	0.031
I36.0 Nonrheumatic tricuspid (valve) stenosis	0.000	0.968	0.031
I38 Endocarditis, valve unspecified	0.000	0.969	0.031
I46.9 Cardiac arrest, unspecified	0.000	0.969	0.031
I37.9 Pulmonary valve disorder, unspecified	0.000	0.969	0.031
I37.8 Other pulmonary valve disorders	0.000	0.969	0.031
I37.2 Pulmonary valve stenosis with insufficiency	0.000	0.969	0.031
I37.0 Pulmonary valve stenosis	0.000	0.969	0.031
I33.9 Acute endocarditis, unspecified	0.000	0.969	0.030
I36.1 Nonrheumatic tricuspid (valve) insufficiency	0.000	0.970	0.030
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.001	0.971	0.028
I42 Cardiomyopathy	0.000	0.972	0.028
I37.1 Pulmonary valve insufficiency	0.000	0.972	0.027
I49 Other cardiac arrhythmias	0.000	0.972	0.028
I33.0 Acute and subacute infective endocarditis	0.000	0.973	0.027
I35.9 Aortic valve disorder, unspecified	0.000	0.973	0.027
I49.0 Ventricular fibrillation and flutter	0.000	0.974	0.026
I35.1 Aortic (valve) insufficiency	0.000	0.974	0.026
I30.8 Other forms of acute pericarditis	0.000	0.975	0.024
I30.0 Acute nonspecific idiopathic pericarditis	0.000	0.975	0.024
I31.8 Other specified diseases of pericardium	0.000	0.976	0.024
I31.2 Haemopericardium, not elsewhere classified	0.000	0.976	0.024
I31.1 Chronic constrictive pericarditis	0.000	0.976	0.024
I31.0 Chronic adhesive pericarditis	0.000	0.976	0.024
I42.6 Alcoholic cardiomyopathy	0.000	0.977	0.023
I42.0 Dilated cardiomyopathy	0.000	0.977	0.023
I35.0 Aortic (valve) stenosis	0.000	0.978	0.022
I30.1 Infective pericarditis	0.000	0.979	0.021
I42.7 Cardiomyopathy due to drugs and other external agents	0.000	0.979	0.021
I42.5 Other restrictive cardiomyopathy	0.000	0.979	0.021
I42.4 Endocardial fibroelastosis	0.000	0.979	0.021
I42.3 Endomyocardial (eosinophilic) disease	0.000	0.979	0.021
I49.2 Junctional premature depolarisation	0.000	0.980	0.020
I31.3 Pericardial effusion (noninflammatory)	0.000	0.980	0.020
G40.9 Epilepsy, unspecified	0.000	0.980	0.020
I35.8 Other aortic valve disorders	0.000	0.981	0.019
I49.1 Atrial premature depolarisation	0.000	0.981	0.019
I42.2 Other hypertrophic cardiomyopathy	0.000	0.982	0.018
G40 Epilepsy	0.000	0.982	0.018
I30.9 Acute pericarditis, unspecified	0.000	0.982	0.018
I31.9 Disease of pericardium, unspecified	0.000	0.982	0.018
I49.8 Other specified cardiac arrhythmias	0.000	0.982	0.018
I42.1 Obstructive hypertrophic cardiomyopathy	0.000	0.982	0.017
G40.6 Grand mal seizures, unspecified (with or without petit mal)	0.000	0.983	0.017
I49.9 Cardiac arrhythmia, unspecified	0.000	0.984	0.016
I35.2 Aortic (valve) stenosis with insufficiency	0.000	0.984	0.016
I49.4 Other and unspecified premature depolarisation	0.000	0.984	0.016
G40.3 Generalised idiopathic epilepsy and epileptic syndromes	0.000	0.984	0.016
I47 Paroxysmal tachycardia	0.000	0.985	0.015
I42.8 Other cardiomyopathies	0.000	0.985	0.015
I49.5 Sick sinus syndrome	0.000	0.985	0.015
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures	0.000	0.986	0.014
I08.0 Disorders of both mitral and aortic valves	0.001	0.986	0.013
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures	0.000	0.986	0.014
R22.4 Localised swelling, mass and lump, lower limb	0.014	0.986	0.000
G40.8 Other epilepsy	0.000	0.987	0.013
G40.7 Petit mal, unspecified, without grand mal seizures	0.000	0.987	0.013
G40.4 Other generalised epilepsy and epileptic syndromes	0.000	0.987	0.013
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset	0.000	0.987	0.013
R22.1 Localised swelling, mass and lump, neck	0.013	0.987	0.000
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters	0.013	0.987	0.000
I42.9 Cardiomyopathy, unspecified	0.000	0.987	0.013
G40.5 Special epileptic syndromes	0.000	0.987	0.013
R22 Localised swelling, mass and lump of skin and subcutaneous tissue	0.013	0.987	0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters	0.013	0.987	0.000
R07 Pain in throat and chest	0.000	0.988	0.012
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.000	0.988	0.012
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters	0.012	0.988	0.000
I95.1 Orthostatic hypotension	0.001	0.988	0.011
R22.0 Localised swelling, mass and lump, head	0.012	0.988	0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters	0.011	0.989	0.000
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters	0.011	0.989	0.000
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters	0.011	0.989	0.000
I49.3 Ventricular premature depolarisation	0.000	0.989	0.011
R07.2 Precordial pain	0.000	0.989	0.011
R22.2 Localised swelling, mass and lump, trunk	0.011	0.989	0.000
R07.0 Pain in throat	0.000	0.990	0.010
I47.9 Paroxysmal tachycardia, unspecified	0.000	0.990	0.010
I47.0 Reentry ventricular arrhythmia	0.000	0.990	0.010
K62.0 Anal polyp	0.009	0.991	0.000
R22.7 Localised swelling, mass and lump, multiple sites	0.009	0.991	0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters	0.009	0.991	0.000
I87 Other disorders of veins	0.000	0.991	0.009
B95.7 Other staphylococcus as the cause of diseases classified to other chapters	0.009	0.991	0.000
G40-G47 Episodic and paroxysmal disorders	0.000	0.991	0.009
M25.46 Effusion of joint (Lower leg)	0.009	0.991	0.000
M65.96 Synovitis and tenosynovitis, unspecified (Lower leg)	0.009	0.991	0.000
I88 Nonspecific lymphadenitis	0.000	0.991	0.009
I34 Nonrheumatic mitral valve disorders	0.000	0.991	0.008
B95.0 Streptococcus, group A, as the cause of diseases classified to other chapters	0.008	0.991	0.000
I51 Complications and ill-defined descriptions of heart disease	0.000	0.992	0.008
K30 Dyspepsia	0.000	0.992	0.008
I47.2 Ventricular tachycardia	0.000	0.992	0.008
G45.3 Amaurosis fugax	0.000	0.992	0.008
F31.9 Bipolar affective disorder, unspecified	0.000	0.992	0.008
I73.0 Raynaud's syndrome	0.000	0.992	0.008
I87.1 Compression of vein	0.000	0.992	0.008
I87.2 Venous insufficiency (chronic) (peripheral)	0.000	0.992	0.008
R22.3 Localised swelling, mass and lump, upper limb	0.008	0.992	0.000
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters	0.008	0.992	0.000
F31 Bipolar affective disorder	0.000	0.992	0.008
G45 Transient cerebral ischaemic attacks and related syndromes	0.000	0.992	0.008
I82 Other venous embolism and thrombosis	0.000	0.992	0.007
I89 Other non-infective disorders of lymphatic vessels and lymph nodes	0.000	0.993	0.007
I51.4 Myocarditis, unspecified	0.000	0.993	0.007
M65.9 Synovitis and tenosynovitis, unspecified	0.007	0.993	0.000
I81 Portal vein thrombosis	0.000	0.993	0.007
K21.9 Gastro-oesophageal reflux disease without oesophagitis	0.000	0.993	0.007
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.000	0.993	0.007
I87.9 Disorder of vein, unspecified	0.000	0.993	0.007
I87.0 Postphlebitic syndrome	0.000	0.993	0.007
I86 Varicose veins of other sites	0.000	0.993	0.007
M65.97 Synovitis and tenosynovitis, unspecified (Ankle and foot)	0.007	0.993	0.000
G47 Sleep disorders	0.000	0.993	0.007
M07.39 Other psoriatic arthropathies (Site unspecified)	0.007	0.993	0.000
G46 Vascular syndromes of brain in cerebrovascular diseases	0.000	0.993	0.007
G41 Status epilepticus	0.000	0.993	0.007
M65.44 Radial styloid tenosynovitis [de Quervain] (Hand)	0.007	0.993	0.000
M65.4 Radial styloid tenosynovitis [de Quervain]	0.007	0.993	0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.000	0.993	0.007
F30-F39 Mood [affective] disorders	0.000	0.993	0.007
I89.1 Lymphangitis	0.000	0.993	0.006
I88.8 Other nonspecific lymphadenitis	0.000	0.993	0.006
I88.1 Chronic lymphadenitis, except mesenteric	0.000	0.993	0.006
I88.0 Nonspecific mesenteric lymphadenitis	0.000	0.993	0.006
G44 Other headache syndromes	0.000	0.993	0.006
M65.90 Synovitis and tenosynovitis, unspecified (Multiple sites)	0.006	0.993	0.000
I34.8 Other nonrheumatic mitral valve disorders	0.000	0.994	0.006
R63.4 Abnormal weight loss	0.000	0.994	0.006
I51.5 Myocardial degeneration	0.000	0.994	0.006
I51.2 Rupture of papillary muscle, not elsewhere classified	0.000	0.994	0.006
I51.0 Cardiac septal defect, acquired	0.000	0.994	0.006
M07.3 Other psoriatic arthropathies	0.006	0.994	0.000
G43 Migraine	0.000	0.994	0.006
I88.9 Nonspecific lymphadenitis, unspecified	0.000	0.994	0.006
R22.9 Localised swelling, mass and lump, unspecified	0.006	0.994	0.000
I73.9 Peripheral vascular disease, unspecified	0.000	0.994	0.006
F32 Depressive episode	0.000	0.994	0.006

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations