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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs11191580
log Bayes Factor = 15.9158
Chromosome 10   position 104,906,211  (GRCh37) Explore rs11191580 on Ensembl!
Variant rs11191580 is listed in the   GWAS Catalog   ⇪
Variant rs11191580 is part of Cluster X0228

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I10 Essential (primary) hypertension
0.000 0.000 1.000
I25 Chronic ischaemic heart disease
0.000 0.000 1.000
I20 Angina pectoris
0.000 0.000 1.000
I20-I25 Ischaemic heart diseases
0.000 0.000 1.000
I20.0 Unstable angina
0.000 0.000 1.000
I20.9 Angina pectoris, unspecified
0.000 0.002 0.998
I25.1 Atherosclerotic heart disease
0.000 0.002 0.998
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.002 0.998
I25.2 Old myocardial infarction
0.000 0.005 0.995
I24 Other acute ischaemic heart diseases
0.000 0.047 0.953
I25.9 Chronic ischaemic heart disease, unspecified
0.000 0.077 0.923
I21 Acute myocardial infarction
0.000 0.079 0.921
I21.4 Acute subendocardial myocardial infarction
0.000 0.147 0.853
I24.8 Other forms of acute ischaemic heart disease
0.000 0.152 0.848
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.176 0.824
I21.0 Acute transmural myocardial infarction of anterior wall
0.000 0.188 0.812
I20.1 Angina pectoris with documented spasm
0.000 0.197 0.802
I22 Subsequent myocardial infarction
0.000 0.208 0.791
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.216 0.784
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.228 0.772
I25.3 Aneurysm of heart
0.000 0.279 0.721
I10-I15 Hypertensive diseases
0.000 0.281 0.719
I25.6 Silent myocardial ischaemia
0.000 0.283 0.717
I25.4 Coronary artery aneurysm
0.000 0.291 0.709
I24.1 Dressler's syndrome
0.000 0.317 0.683
I25.5 Ischaemic cardiomyopathy
0.000 0.321 0.679
I21.2 Acute transmural myocardial infarction of other sites
0.000 0.330 0.670
I21.3 Acute transmural myocardial infarction of unspecified site
0.000 0.334 0.666
I21.X Presumed acute myicardial infaction (unconfirmed)
0.000 0.339 0.660
I23 Certain current complications following acute myocardial infarction
0.000 0.355 0.645
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.365 0.635
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.391 0.609
Chapter IX Diseases of the circulatory system
0.000 0.415 0.585
I15 Secondary hypertension
0.000 0.420 0.580
I22.8 Subsequent myocardial infarction of other sites
0.000 0.428 0.572
I21.1 Acute transmural myocardial infarction of inferior wall
0.000 0.442 0.558
I21.9 Acute myocardial infarction, unspecified
0.000 0.471 0.529
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.475 0.525
I13 Hypertensive heart and renal disease
0.000 0.484 0.516
I15.1 Hypertension secondary to other renal disorders
0.000 0.520 0.480
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.000 0.537 0.462
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.000 0.537 0.462
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.000 0.537 0.462
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.000 0.537 0.462
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.000 0.537 0.462
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.000 0.537 0.462
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.000 0.537 0.462
I20.8 Other forms of angina pectoris
0.000 0.546 0.454
I11 Hypertensive heart disease
0.000 0.562 0.438
I00-I02 Acute rheumatic fever
0.000 0.580 0.419
I15.9 Seconday hypertension, unspecified
0.000 0.584 0.416
I15.8 Other secondary hypertension
0.000 0.584 0.416
I15.2 Hypertension secondary to endocrine disorders
0.000 0.584 0.416
I15.0 Renovascular hypertension
0.000 0.584 0.416
I12 Hypertensive renal disease
0.000 0.602 0.398
I23.8 Other current complications following acute myocardial infarction
0.000 0.609 0.390
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.630 0.370
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.000 0.630 0.370
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.630 0.370
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.630 0.370
I02 Rheumatic chorea
0.000 0.699 0.301
I01 Rheumatic fever with heart involvement
0.000 0.699 0.301
I00 Rheumatic fever without mention of heart involvement
0.000 0.699 0.301
I12.9 Hypertensive renal disease without renal failure
0.000 0.701 0.299
I95-I99 Other and unspecified disorders of the circulatory system
0.000 0.714 0.286
I11.0 Hypertensive heart disease with (congestive) heart failure
0.000 0.720 0.280
I11.9 Hypertensive heart disease without (congestive) heart failure
0.000 0.720 0.279
I60-I69 Cerebrovascular diseases
0.000 0.743 0.257
I99 Other and unspecified disorders of circulatory system
0.000 0.761 0.239
I01.9 Acute rheumatic heart disease, unspecified
0.000 0.784 0.216
I01.8 Other acute rheumatic heart disease
0.000 0.784 0.216
I01.2 Acute rheumatic myocarditis
0.000 0.784 0.216
I01.1 Acute rheumatic endocarditis
0.000 0.784 0.216
I01.0 Acute rheumatic pericarditis
0.000 0.784 0.216
I02.9 Rheumatic chorea without heart involvement
0.000 0.784 0.216
I02.0 Rheumatic chorea with heart involvement
0.000 0.784 0.216
I64 Stroke, not specified as haemorrhage or infarction
0.000 0.787 0.213
I98 Other disorders of circulatory system in diseases classified elsewhere
0.000 0.789 0.211
I62 Other nontraumatic intracranial haemorrhage
0.000 0.796 0.204
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.000 0.808 0.192
I69 Sequelae of cerebrovascular disease
0.000 0.812 0.188
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.000 0.816 0.184
I05-I09 Chronic rheumatic heart diseases
0.000 0.823 0.177
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.000 0.825 0.175
I63 Cerebral infarction
0.000 0.828 0.172
I62.9 Intracranial haemorrhage (nontraumatic), unspecified
0.000 0.833 0.166
I98.2 Oesophageal varices in diseases classified elsewhere
0.000 0.836 0.164
I68 Cerebrovascular disorders in diseases classified elsewhere
0.000 0.837 0.163
I60 Subarachnoid haemorrhage
0.000 0.840 0.160
I65.2 Occlusion and stenosis of carotid artery
0.000 0.843 0.157
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.843 0.156
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere
0.000 0.848 0.151
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.848 0.151
I98.0 Cardiovascular syphilis
0.000 0.848 0.151
I69.1 Sequelae of intracerebral haemorrhage
0.000 0.853 0.147
I62.1 Nontraumatic extradural haemorrhage
0.000 0.853 0.146
I62.0 Subdural haemorrhage (acute) (nontraumatic)
0.000 0.853 0.147
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.000 0.854 0.146
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere
0.000 0.857 0.142
I67 Other cerebrovascular diseases
0.000 0.859 0.141
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.000 0.859 0.141
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.000 0.859 0.140
I65.9 Occlusion and stenosis of unspecified precerebral artery
0.000 0.862 0.138
I65.8 Occlusion and stenosis of other precerebral artery
0.000 0.862 0.138
I65.1 Occlusion and stenosis of basilar artery
0.000 0.862 0.138
I65.0 Occlusion and stenosis of vertebral artery
0.000 0.862 0.138
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.000 0.863 0.137
I12.0 Hypertensive renal disease with renal failure
0.000 0.864 0.136
I69.3 Sequelae of cerebral infarction
0.000 0.864 0.136
I66.9 Occlusion and stenosis of unspecified cerebral artery
0.000 0.868 0.132
I66.8 Occlusion and stenosis of other cerebral artery
0.000 0.868 0.132
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries
0.000 0.868 0.132
I66.3 Occlusion and stenosis of cerebellar arteries
0.000 0.868 0.132
I66.2 Occlusion and stenosis of posterior cerebral artery
0.000 0.868 0.132
I66.1 Occlusion and stenosis of anterior cerebral artery
0.000 0.868 0.132
I66.0 Occlusion and stenosis of middle cerebral artery
0.000 0.868 0.132
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.000 0.868 0.132
I60.3 Subarachnoid haemorrhage from posterior communicating artery
0.000 0.869 0.131
I63.8 Other cerebral infarction
0.000 0.871 0.129
I06 Rheumatic aortic valve diseases
0.000 0.873 0.127
I60.8 Other subarachnoid haemorrhage
0.000 0.874 0.126
I09 Other rheumatic heart diseases
0.000 0.876 0.124
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.000 0.876 0.124
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.000 0.876 0.124
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.000 0.876 0.124
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.000 0.876 0.124
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries
0.000 0.880 0.120
I07 Rheumatic tricuspid valve diseases
0.000 0.880 0.120
I67.1 Cerebral aneurysm, nonruptured
0.000 0.881 0.119
I97.2 Postmastectomy lymphoedema syndrome
0.000 0.881 0.119
I68.8 Other cerebrovascular disorders in diseases classified elsewhere
0.000 0.883 0.117
I68.2 Cerebral arteritis in other diseases classified elsewhere
0.000 0.883 0.117
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere
0.000 0.883 0.117
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.000 0.885 0.115
I60.5 Subarachnoid haemorrhage from vertebral artery
0.000 0.885 0.115
I60.4 Subarachnoid haemorrhage from basilar artery
0.000 0.885 0.115
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation
0.000 0.885 0.115
I60.1 Subarachnoid haemorrhage from middle cerebral artery
0.000 0.886 0.114
I97.9 Postprocedural disorder of circulatory system, unspecified
0.000 0.887 0.112
I97.0 Postcardiotomy syndrome
0.000 0.887 0.112
I69.0 Sequelae of subarachnoid haemorrhage
0.000 0.888 0.112
I67.2 Cerebral atherosclerosis
0.000 0.888 0.112
I60.2 Subarachnoid haemorrhage from anterior communicating artery
0.000 0.889 0.111
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified
0.000 0.894 0.106
I28 Other diseases of pulmonary vessels
0.001 0.894 0.106
K21.9 Gastro-oesophageal reflux disease without oesophagitis
0.000 0.895 0.105
I67.7 Cerebral arteritis, not elsewhere classified
0.000 0.898 0.102
I67.6 Nonpyogenic thrombosis of intracranial venous system
0.000 0.898 0.102
I67.5 Moyamoya disease
0.000 0.898 0.102
I67.4 Hypertensive encephalopathy
0.000 0.898 0.102
I67.3 Progressive vascular leukoencephalopathy
0.000 0.898 0.102
I67.0 Dissection of cerebral arteries, nonruptured
0.000 0.898 0.102
I60.6 Subarachnoid haemorrhage from other intracranial arteries
0.000 0.900 0.100
I68.0 Cerebral amyloid angiopathy
0.000 0.904 0.095
K30 Dyspepsia
0.000 0.908 0.092
I97.1 Other functional disturbances following cardiac surgery
0.001 0.908 0.091
I06.9 Rheumatic aortic valve disease, unspecified
0.000 0.908 0.091
I06.8 Other rheumatic aortic valve diseases
0.000 0.908 0.091
I06.2 Rheumatic aortic stenosis with insufficiency
0.000 0.908 0.091
I06.1 Rheumatic aortic insufficiency
0.000 0.908 0.091
I06.0 Rheumatic aortic stenosis
0.000 0.908 0.091
I09.8 Other specified rheumatic heart diseases
0.000 0.911 0.089
I09.2 Chronic rheumatic pericarditis
0.000 0.911 0.089
I09.1 Rheumatic diseases of endocardium, valve unspecified
0.000 0.911 0.089
I09.0 Rheumatic myocarditis
0.000 0.911 0.089
I05 Rheumatic mitral valve diseases
0.001 0.911 0.089
I07.9 Tricuspid valve disease, unspecified
0.000 0.914 0.086
I07.8 Other tricuspid valve diseases
0.000 0.914 0.086
I07.2 Tricuspid stenosis with insufficiency
0.000 0.914 0.086
I07.0 Tricuspid stenosis
0.000 0.914 0.086
I09.9 Rheumatic heart disease, unspecified
0.000 0.914 0.086
I27 Other pulmonary heart diseases
0.001 0.917 0.083
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified
0.001 0.917 0.082
I07.1 Tricuspid insufficiency
0.000 0.921 0.079
I28.9 Disease of pulmonary vessels, unspecified
0.001 0.924 0.076
I28.1 Aneurysm of pulmonary artery
0.001 0.924 0.076
I28.0 Arteriovenous fistula of pulmonary vessels
0.001 0.924 0.076
I60.9 Subarachnoid haemorrhage, unspecified
0.000 0.927 0.073
I05.8 Other mitral valve diseases
0.001 0.936 0.064
I05.1 Rheumatic mitral insufficiency
0.001 0.936 0.064
I05.9 Mitral valve disease, unspecified
0.001 0.937 0.063
I26 Pulmonary embolism
0.001 0.937 0.062
I27.0 Primary pulmonary hypertension
0.000 0.938 0.062
I27.8 Other specified pulmonary heart diseases
0.000 0.939 0.060
I27.1 Kyphoscoliotic heart disease
0.001 0.940 0.060
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.942 0.058
I61 Intracerebral haemorrhage
0.002 0.942 0.057
I67.8 Other specified cerebrovascular diseases
0.000 0.942 0.057
I28.8 Other specified diseases of pulmonary vessels
0.001 0.943 0.056
I27.9 Pulmonary heart disease, unspecified
0.001 0.947 0.053
I05.2 Mitral stenosis with insufficiency
0.001 0.948 0.052
R07.4 Chest pain, unspecified
0.000 0.948 0.052
I05.0 Mitral stenosis
0.001 0.951 0.048
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.954 0.046
I67.9 Cerebrovascular disease, unspecified
0.000 0.954 0.046
I61.5 Intracerebral haemorrhage, intraventricular
0.001 0.957 0.042
I61.6 Intracerebral haemorrhage, multiple localised
0.001 0.958 0.041
I61.2 Intracerebral haemorrhage in hemisphere, unspecified
0.001 0.958 0.041
I77 Other disorders of arteries and arterioles
0.000 0.959 0.041
I61.0 Intracerebral haemorrhage in hemisphere, subcortical
0.001 0.959 0.039
I08 Multiple valve diseases
0.001 0.960 0.040
I61.8 Other intracerebral haemorrhage
0.001 0.961 0.038
I61.3 Intracerebral haemorrhage in brain stem
0.001 0.961 0.038
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.001 0.961 0.038
I61.4 Intracerebral haemorrhage in cerebellum
0.001 0.961 0.037
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.000 0.962 0.038
I95 Hypotension
0.001 0.964 0.036
I77.1 Stricture of artery
0.000 0.966 0.034
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.966 0.033
I79.1 Aortitis in diseases classified elsewhere
0.000 0.966 0.033
I79.0 Aneurysm of aorta in diseases classified elsewhere
0.000 0.966 0.033
I72 Other aneurysm
0.000 0.967 0.033
I74 Arterial embolism and thrombosis
0.000 0.967 0.033
I70 Atherosclerosis
0.000 0.967 0.033
I78 Diseases of capillaries
0.000 0.968 0.032
Z95.5 Presence of coronary angioplasty implant and graft
0.000 0.968 0.032
I77.9 Disorder of arteries and arterioles, unspecified
0.000 0.968 0.032
I77.5 Necrosis of artery
0.000 0.970 0.030
I77.4 Coeliac artery compression syndrome
0.000 0.970 0.030
I77.3 Arterial fibromuscular dysplasia
0.000 0.970 0.030
I77.2 Rupture of artery
0.000 0.970 0.030
K21 Gastro-oesophageal reflux disease
0.000 0.970 0.030
I08.2 Disorders of both aortic and tricuspid valves
0.001 0.970 0.029
I08.9 Multiple valve disease, unspecified
0.001 0.971 0.028
I77.6 Arteritis, unspecified
0.000 0.971 0.029
I61.1 Intracerebral haemorrhage in hemisphere, cortical
0.002 0.971 0.027
I71 Aortic aneurysm and dissection
0.000 0.972 0.028
I74.5 Embolism and thrombosis of iliac artery
0.000 0.972 0.028
I08.8 Other multiple valve diseases
0.001 0.973 0.026
I72.0 Aneurysm of carotid artery
0.000 0.974 0.026
I77.8 Other specified disorders of arteries and arterioles
0.000 0.974 0.026
I95.8 Other hypotension
0.001 0.974 0.026
I95.0 Idiopathic hypotension
0.000 0.974 0.025
I77.0 Arteriovenous fistula, acquired
0.000 0.974 0.026
I63.9 Cerebral infarction, unspecified
0.000 0.974 0.026
I72.8 Aneurysm of other specified arteries
0.000 0.975 0.025
I27.2 Other secondary pulmonary hypertension
0.001 0.975 0.024
I72.6 Aneurysm and dissection of vertebral artery
0.000 0.976 0.024
I72.5 Aneurysm and dissection of other precerebral arteries
0.000 0.976 0.024
I72.2 Aneurysm of renal artery
0.000 0.976 0.024
I72.1 Aneurysm of artery of upper extremity
0.000 0.976 0.024
I08.1 Disorders of both mitral and tricuspid valves
0.000 0.976 0.024
I70.9 Generalised and unspecified atherosclerosis
0.000 0.976 0.024
I70.8 Atherosclerosis of other arteries
0.000 0.976 0.024
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.000 0.976 0.024
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.000 0.976 0.024
I74.0 Embolism and thrombosis of abdominal aorta
0.000 0.976 0.024
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.000 0.976 0.023
I78.9 Disease of capillaries, unspecified
0.000 0.977 0.023
I70.1 Atherosclerosis of renal artery
0.000 0.977 0.023
Z95.1 Presence of aortocoronary bypass graft
0.000 0.977 0.023
I72.4 Aneurysm of artery of lower extremity
0.000 0.977 0.023
I78.8 Other diseases of capillaries
0.000 0.977 0.023
I74.8 Embolism and thrombosis of other arteries
0.000 0.977 0.023
Z95 Presence of cardiac and vascular implants and grafts
0.000 0.978 0.022
I78.0 Hereditary haemorrhagic telangiectasia
0.000 0.978 0.022
I71.3 Abdominal aortic aneurysm, ruptured
0.000 0.978 0.022
I72.9 Aneurysm of unspecified site
0.000 0.978 0.021
I70.0 Atherosclerosis of aorta
0.000 0.979 0.021
I71.0 Dissection of aorta [any part]
0.000 0.979 0.021
I71.8 Aortic aneurysm of unspecified site, ruptured
0.000 0.980 0.020
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.000 0.980 0.020
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.000 0.980 0.020
I71.1 Thoracic aortic aneurysm, ruptured
0.000 0.980 0.020
I74.9 Embolism and thrombosis of unspecified artery
0.000 0.980 0.020
I70.2 Atherosclerosis of arteries of the extremities
0.000 0.980 0.020
Z95.8 Presence of other cardiac and vascular implants and grafts
0.000 0.981 0.019
R07 Pain in throat and chest
0.000 0.981 0.019
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.001 0.981 0.018
I95.2 Hypotension due to drugs
0.001 0.982 0.018
Z95.3 Presence of xenogenic heart valve
0.000 0.982 0.018
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.000 0.982 0.018
I70.81 Atherosclerosis of other arteries (with gangrene)
0.000 0.983 0.017
I70.80 Atherosclerosis of other arteries (without gangrene)
0.000 0.983 0.017
I70.91 Generalized and unspecified atherosclerosis (with gangrene)
0.000 0.983 0.017
I70.90 Generalized and unspecified atherosclerosis (without gangrene)
0.000 0.983 0.017
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.000 0.983 0.017
I70.11 Atherosclerosis of renal artery (with gangrene)
0.000 0.983 0.017
I70.10 Atherosclerosis of renal artery (without gangrene)
0.000 0.984 0.016
I78.1 Naevus, nonneoplastic
0.000 0.984 0.016
I72.3 Aneurysm of iliac artery
0.001 0.984 0.015
I70.01 Atherosclerosis of aorta (with gangrene)
0.000 0.985 0.015
R07.2 Precordial pain
0.000 0.985 0.015
I61.9 Intracerebral haemorrhage, unspecified
0.002 0.985 0.012
Z95.4 Presence of other heart-valve replacement
0.000 0.985 0.015
I30-I52 Other forms of heart disease
0.000 0.985 0.015
R07.0 Pain in throat
0.000 0.986 0.014
Z95.2 Presence of prosthetic heart valve
0.000 0.986 0.014
I45 Other conduction disorders
0.000 0.986 0.014
I45.1 Other and unspecified right bundle-branch block
0.000 0.986 0.014
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.000 0.986 0.014
K20-K31 Diseases of oesophagus, stomach and duodenum
0.000 0.986 0.014
M20.1 Hallux valgus (acquired)
0.013 0.987 0.000
R07.3 Other chest pain
0.000 0.987 0.013
I70.20 Atherosclerosis of arteries of extremities (without gangrene)
0.000 0.987 0.013
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.000 0.987 0.013
I73 Other peripheral vascular diseases
0.000 0.987 0.013
I70.21 Atherosclerosis of arteries of extremities (with gangrene)
0.000 0.987 0.012
I44 Atrioventricular and left bundle-branch block
0.000 0.988 0.012
I70.00 Atherosclerosis of aorta (without gangrene)
0.000 0.988 0.012
I44.1 Atrioventricular block, second degree
0.000 0.988 0.012
I50 Heart failure
0.000 0.988 0.012
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.000 0.988 0.012
I50.1 Left ventricular failure
0.000 0.988 0.012
M25.46 Effusion of joint (Lower leg)
0.012 0.988 0.000
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters
0.012 0.988 0.000
K27 Peptic ulcer, site unspecified
0.000 0.989 0.011
I45.6 Preexcitation syndrome
0.000 0.989 0.011
I37 Pulmonary valve disorders
0.000 0.989 0.011
K62.0 Anal polyp
0.011 0.989 0.000
I44.7 Left bundle-branch block, unspecified
0.000 0.989 0.011
I36 Nonrheumatic tricuspid valve disorders
0.000 0.989 0.011
I52 Other heart disorders in diseases classified elsewhere
0.000 0.989 0.011
I48 Atrial fibrillation and flutter
0.000 0.989 0.011
I43 Cardiomyopathy in diseases classified elsewhere
0.000 0.989 0.011
I41 Myocarditis in diseases classified elsewhere
0.000 0.989 0.011
I40 Acute myocarditis
0.000 0.989 0.011
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.000 0.989 0.011
I32 Pericarditis in diseases classified elsewhere
0.000 0.989 0.011
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.011 0.989 0.000
I45.8 Other specified conduction disorders
0.000 0.990 0.010
I45.4 Nonspecific intraventricular block
0.000 0.990 0.010
I45.0 Right fascicular block
0.000 0.990 0.010
I45.3 Trifascicular block
0.000 0.990 0.010
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters
0.010 0.990 0.000
I45.2 Bifascicular block
0.000 0.990 0.010
K23 Disorders of oesophagus in diseases classified elsewhere
0.000 0.990 0.010
I45.9 Conduction disorder, unspecified
0.000 0.990 0.010
K27.9 Unspecified as acute or chronic, without haemorrhage or perforation
0.000 0.990 0.010
K28 Gastrojejunal ulcer
0.000 0.990 0.010
I46 Cardiac arrest
0.000 0.990 0.010
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters
0.010 0.990 0.000
I33 Acute and subacute endocarditis
0.000 0.990 0.009
I73.1 Thromboangiitis obliterans [Buerger]
0.000 0.990 0.009
I44.6 Other and unspecified fascicular block
0.000 0.991 0.009
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters
0.009 0.991 0.000
I44.5 Left posterior fascicular block
0.000 0.991 0.009
I38 Endocarditis, valve unspecified
0.000 0.991 0.009
I08.0 Disorders of both mitral and aortic valves
0.002 0.991 0.008
I30 Acute pericarditis
0.000 0.991 0.009
I45.5 Other specified heart block
0.000 0.991 0.009
I37.1 Pulmonary valve insufficiency
0.000 0.991 0.009
I73.8 Other specified peripheral vascular diseases
0.000 0.991 0.009
Z95.0 Presence of cardiac pacemaker
0.000 0.991 0.009
I44.3 Other and unspecified atrioventricular block
0.000 0.991 0.009
B95.4 Other streptococcus as the cause of diseases classified to other chapters
0.008 0.992 0.000
K27.7 Chronic without haemorrhage or perforation
0.000 0.992 0.008
K27.6 Chronic or unspecified with both haemorrhage and perforation
0.000 0.992 0.008
K27.5 Chronic or unspecified with perforation
0.000 0.992 0.008
K27.4 Chronic or unspecified with haemorrhage
0.000 0.992 0.008
K27.3 Acute without haemorrhage or perforation
0.000 0.992 0.008
K27.2 Acute with both haemorrhage and perforation
0.000 0.992 0.008
K27.1 Acute with perforation
0.000 0.992 0.008
K27.0 Acute with haemorrhage
0.000 0.992 0.008
I37.9 Pulmonary valve disorder, unspecified
0.000 0.992 0.008
I37.8 Other pulmonary valve disorders
0.000 0.992 0.008
I37.2 Pulmonary valve stenosis with insufficiency
0.000 0.992 0.008
I37.0 Pulmonary valve stenosis
0.000 0.992 0.008
I36.1 Nonrheumatic tricuspid (valve) insufficiency
0.000 0.992 0.008
I36.9 Nonrheumatic tricuspid valve disorder, unspecified
0.000 0.992 0.008
I36.8 Other nonrheumatic tricuspid valve disorders
0.000 0.992 0.008
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency
0.000 0.992 0.008
I36.0 Nonrheumatic tricuspid (valve) stenosis
0.000 0.992 0.008
R07.1 Chest pain on breathing
0.000 0.992 0.008
I32.8 Pericarditis in other diseases classified elsewhere
0.000 0.992 0.008
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere
0.000 0.992 0.008
I32.0 Pericarditis in bacterial diseases classified elsewhere
0.000 0.992 0.008
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere
0.000 0.992 0.008
I39.4 Multiple valve disorders in diseases classified elsewhere
0.000 0.992 0.008
I39.3 Pulmonary valve disorders in diseases classified elsewhere
0.000 0.992 0.008
I39.2 Tricuspid valve disorders in diseases classified elsewhere
0.000 0.992 0.008
I39.1 Aortic valve disorders in diseases classified elsewhere
0.000 0.992 0.008
I39.0 Mitral valve disorders in diseases classified elsewhere
0.000 0.992 0.008
I40.9 Acute myocarditis, unspecified
0.000 0.992 0.008
I40.8 Other acute myocarditis
0.000 0.992 0.008
I40.1 Isolated myocarditis
0.000 0.992 0.008
I40.0 Infective myocarditis
0.000 0.992 0.008
I41.8 Myocarditis in other diseases classified elsewhere
0.000 0.992 0.008
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere
0.000 0.992 0.008
I41.1 Myocarditis in viral diseases classified elsewhere
0.000 0.992 0.008
I41.0 Myocarditis in bacterial diseases classified elsewhere
0.000 0.992 0.008
I43.8 Cardiomyopathy in other diseases classified elsewhere
0.000 0.992 0.008
I43.2 Cardiomyopathy in nutritional diseases
0.000 0.992 0.008
I43.1 Cardiomyopathy in metabolic diseases
0.000 0.992 0.008
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere
0.000 0.992 0.008
I48.9 Atrial fibrillation and atrial flutter, unspecified
0.000 0.992 0.008
I48.4 Atypical atrial flutter
0.000 0.992 0.008
I48.3 Typical atrial flutter
0.000 0.992 0.008
I48.2 Chronic atrial fibrillation
0.000 0.992 0.008
I48.1 Persistent atrial fibrillation
0.000 0.992 0.008
I48.0 Paroxysmal atrial fibrillation
0.000 0.992 0.008
I52.8 Other heart disorders in other diseases classified elsewhere
0.000 0.992 0.008
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.992 0.008
I52.0 Other heart disorders in bacterial diseases classified elsewhere
0.000 0.992 0.008
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.000 0.992 0.008
K26 Duodenal ulcer
0.000 0.992 0.008
I35 Nonrheumatic aortic valve disorders
0.000 0.992 0.008
I44.0 Atrioventricular block, first degree
0.000 0.992 0.008
M65.96 Synovitis and tenosynovitis, unspecified (Lower leg)
0.008 0.992 0.000
B95.0 Streptococcus, group A, as the cause of diseases classified to other chapters
0.008 0.992 0.000
F31.9 Bipolar affective disorder, unspecified
0.000 0.992 0.008
I49 Other cardiac arrhythmias
0.000 0.992 0.008
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.008 0.992 0.000
K23.8 Disorders of oesophagus in other diseases classified elsewhere
0.000 0.993 0.007
K23.1 Megaoesophagus in Chagas' disease
0.000 0.993 0.007
K23.0 Tuberculous oesophagitis
0.000 0.993 0.007
I44.4 Left anterior fascicular block
0.000 0.993 0.007
K26.3 Acute without haemorrhage or perforation
0.000 0.993 0.007
B95.7 Other staphylococcus as the cause of diseases classified to other chapters
0.007 0.993 0.000
I46.0 Cardiac arrest with successful resuscitation
0.000 0.993 0.007
I50.9 Heart failure, unspecified
0.000 0.993 0.007
K28.7 Chronic without haemorrhage or perforation
0.000 0.993 0.007
K28.6 Chronic or unspecified with both haemorrhage and perforation
0.000 0.993 0.007
K28.5 Chronic or unspecified with perforation
0.000 0.993 0.007
K28.4 Chronic or unspecified with haemorrhage
0.000 0.993 0.007
K28.3 Acute without haemorrhage or perforation
0.000 0.993 0.007
K28.2 Acute with both haemorrhage and perforation
0.000 0.993 0.007
K28.1 Acute with perforation
0.000 0.993 0.007
K28.0 Acute with haemorrhage
0.000 0.993 0.007
I42 Cardiomyopathy
0.000 0.993 0.007
I46.1 Sudden cardiac death, so described
0.000 0.993 0.007
I33.9 Acute endocarditis, unspecified
0.000 0.993 0.007
I95.1 Orthostatic hypotension
0.000 0.993 0.007
I44.2 Atrioventricular block, complete
0.000 0.993 0.007
I49.0 Ventricular fibrillation and flutter
0.000 0.993 0.007
K28.9 Unspecified as acute or chronic, without haemorrhage or perforation
0.000 0.993 0.007
I30.8 Other forms of acute pericarditis
0.000 0.993 0.006
I30.0 Acute nonspecific idiopathic pericarditis
0.000 0.993 0.006
F31 Bipolar affective disorder
0.000 0.993 0.007
M54.36 Sciatica (Lumbar region)
0.000 0.993 0.007
K26.5 Chronic or unspecified with perforation
0.000 0.994 0.006
Z88.6 Personal history of allergy to analgesic agent
0.000 0.994 0.006
I31 Other diseases of pericardium
0.000 0.994 0.006
I35.9 Aortic valve disorder, unspecified
0.000 0.994 0.006
L98.9 Disorder of skin and subcutaneous tissue, unspecified
0.006 0.994 0.000
I30.1 Infective pericarditis
0.000 0.994 0.006
K26.7 Chronic without haemorrhage or perforation
0.000 0.994 0.006
M65.9 Synovitis and tenosynovitis, unspecified
0.006 0.994 0.000
M65.44 Radial styloid tenosynovitis [de Quervain] (Hand)
0.006 0.994 0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression
0.000 0.994 0.006
H00.1 Chalazion
0.006 0.994 0.000
I35.0 Aortic (valve) stenosis
0.000 0.994 0.006
K26.6 Chronic or unspecified with both haemorrhage and perforation
0.000 0.994 0.006
K26.2 Acute with both haemorrhage and perforation
0.000 0.994 0.006
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms
0.000 0.994 0.006
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters
0.006 0.994 0.000
I33.0 Acute and subacute infective endocarditis
0.000 0.994 0.006
M65.4 Radial styloid tenosynovitis [de Quervain]
0.006 0.994 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.000 0.994 0.006
I49.9 Cardiac arrhythmia, unspecified
0.000 0.994 0.006
M54.3 Sciatica
0.000 0.994 0.006
I49.2 Junctional premature depolarisation
0.000 0.994 0.006
I42.0 Dilated cardiomyopathy
0.000 0.994 0.006
F31.0 Bipolar affective disorder, current episode hypomanic
0.000 0.994 0.006
I46.9 Cardiac arrest, unspecified
0.000 0.994 0.006
I49.8 Other specified cardiac arrhythmias
0.000 0.994 0.006
I88 Nonspecific lymphadenitis
0.000 0.994 0.005
I30.9 Acute pericarditis, unspecified
0.000 0.994 0.005
K26.0 Acute with haemorrhage
0.000 0.994 0.005
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms
0.000 0.995 0.005
I89.1 Lymphangitis
0.000 0.995 0.005
I42.7 Cardiomyopathy due to drugs and other external agents
0.000 0.995 0.005
I42.6 Alcoholic cardiomyopathy
0.000 0.995 0.005
I42.5 Other restrictive cardiomyopathy
0.000 0.995 0.005
I42.4 Endocardial fibroelastosis
0.000 0.995 0.005
I42.3 Endomyocardial (eosinophilic) disease
0.000 0.995 0.005
H43.8 Other disorders of vitreous body
0.005 0.995 0.000
K26.1 Acute with perforation
0.000 0.995 0.005
I35.1 Aortic (valve) insufficiency
0.000 0.995 0.005
I86 Varicose veins of other sites
0.000 0.995 0.005
M65.97 Synovitis and tenosynovitis, unspecified (Ankle and foot)
0.005 0.995 0.000
I50.0 Congestive heart failure
0.000 0.995 0.005
H43 Disorders of vitreous body
0.005 0.995 0.000
I87 Other disorders of veins
0.000 0.995 0.005
I81 Portal vein thrombosis
0.000 0.995 0.005
I49.4 Other and unspecified premature depolarisation
0.000 0.995 0.005
R63.4 Abnormal weight loss
0.000 0.995 0.005
M65.43 Radial styloid tenosynovitis [de Quervain] (Forearm)
0.005 0.995 0.000
I42.2 Other hypertrophic cardiomyopathy
0.000 0.995 0.005
M65.90 Synovitis and tenosynovitis, unspecified (Multiple sites)
0.005 0.995 0.000
I49.1 Atrial premature depolarisation
0.000 0.995 0.005
M54 Dorsalgia
0.000 0.995 0.005
I42.1 Obstructive hypertrophic cardiomyopathy
0.000 0.995 0.005
M54.9 Dorsalgia, unspecified
0.000 0.995 0.005
H52.1 Myopia
0.005 0.995 0.000
F31.8 Other bipolar affective disorders
0.000 0.995 0.005
F31.7 Bipolar affective disorder, currently in remission
0.000 0.995 0.005
F31.6 Bipolar affective disorder, current episode mixed
0.000 0.995 0.005
I35.8 Other aortic valve disorders
0.000 0.995 0.005
M65 Synovitis and tenosynovitis
0.005 0.995 0.000
M54.64 Pain in thoracic spine (Thoracic region)
0.000 0.995 0.005
M54.6 Pain in thoracic spine
0.000 0.995 0.005
H43.1 Vitreous haemorrhage
0.005 0.995 0.000
H43.3 Other vitreous opacities
0.005 0.995 0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms
0.000 0.995 0.005
I31.8 Other specified diseases of pericardium
0.000 0.995 0.005
I31.2 Haemopericardium, not elsewhere classified
0.000 0.995 0.005
I31.1 Chronic constrictive pericarditis
0.000 0.995 0.005
I31.0 Chronic adhesive pericarditis
0.000 0.995 0.005
M54.99 Dorsalgia, unspecified (Site unspecified)
0.000 0.995 0.005

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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