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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs111958418
log Bayes Factor = 20.8287
Chromosome 9   position 22,219,565  (GRCh37) Explore rs111958418 on Ensembl!
Variant rs111958418 is part of Cluster X0201

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter II Neoplasms
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
C79 Secondary malignant neoplasm of other sites
1.000 0.000 0.000
I60-I69 Cerebrovascular diseases
0.999 0.001 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.999 0.001 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.996 0.004 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.996 0.004 0.000
Chapter XX External causes of morbidity and mortality
0.995 0.005 0.000
Chapter V Mental and behavioural disorders
0.993 0.007 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.993 0.007 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.992 0.008 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.991 0.009 0.000
Chapter XXI Factors influencing health status and contact with health services
0.989 0.011 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.988 0.012 0.000
Chapter XI Diseases of the digestive system
0.986 0.014 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.983 0.017 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.983 0.017 0.000
I30-I52 Other forms of heart disease
0.980 0.020 0.000
R29.6 Tendency to fall, not elsewhere classified
0.978 0.022 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.977 0.023 0.000
Z72 Problems related to lifestyle
0.971 0.029 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.971 0.029 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.971 0.029 0.000
M50-M54 Other dorsopathies
0.969 0.031 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.969 0.031 0.000
Z72.0 Tobacco use
0.967 0.033 0.000
I63 Cerebral infarction
0.965 0.035 0.000
Chapter VII Diseases of the eye and adnexa
0.962 0.038 0.000
Z50 Care involving use of rehabilitation procedures
0.961 0.039 0.000
M54 Dorsalgia
0.960 0.040 0.000
F20 Schizophrenia
0.957 0.043 0.000
K13 Other diseases of lip and oral mucosa
0.955 0.045 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.954 0.046 0.000
I50 Heart failure
0.953 0.047 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.953 0.047 0.000
Z50.1 Other physical therapy
0.949 0.051 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.948 0.052 0.000
M54.5 Low back pain
0.947 0.053 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.946 0.054 0.000
I67 Other cerebrovascular diseases
0.945 0.055 0.000
K13.7 Other and unspecified lesions of oral mucosa
0.944 0.056 0.000
I50.0 Congestive heart failure
0.944 0.056 0.000
L40-L45 Papulosquamous disorders
0.941 0.059 0.000
R26 Abnormalities of gait and mobility
0.941 0.059 0.000
I63.9 Cerebral infarction, unspecified
0.940 0.060 0.000
C15-C26 Malignant neoplasms of digestive organs
0.938 0.062 0.000
F20.9 Schizophrenia, unspecified
0.935 0.065 0.000
R91 Abnormal findings on diagnostic imaging of lung
0.932 0.068 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.930 0.070 0.000
C50-C50 Malignant neoplasm of breast
0.929 0.071 0.000
M54.59 Low back pain (Site unspecified)
0.926 0.074 0.000
K65-K67 Diseases of peritoneum
0.924 0.076 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.924 0.076 0.000
L82 Seborrhoeic keratosis
0.921 0.079 0.000
L20-L30 Dermatitis and eczema
0.914 0.086 0.000
L40 Psoriasis
0.911 0.089 0.000
M80-M85 Disorders of bone density and structure
0.911 0.089 0.000
Chapter VI Diseases of the nervous system
0.907 0.093 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.905 0.095 0.000
S40-S49 Injuries to the shoulder and upper arm
0.902 0.098 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.900 0.100 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.895 0.105 0.000
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
0.892 0.108 0.000
K83 Other diseases of biliary tract
0.892 0.108 0.000
E00-E07 Disorders of thyroid gland
0.891 0.109 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.890 0.110 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.888 0.111 0.000
Z47 Other orthopaedic follow-up care
0.887 0.113 0.000
R26.8 Other and unspecified abnormalities of gait and mobility
0.886 0.114 0.000
K14 Diseases of tongue
0.884 0.116 0.000
C18 Malignant neoplasm of colon
0.880 0.120 0.000
K66 Other disorders of peritoneum
0.878 0.122 0.000
C50 Malignant neoplasm of breast
0.878 0.122 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.874 0.126 0.000
K35-K38 Diseases of appendix
0.873 0.127 0.000
E50-E64 Other nutritional deficiencies
0.873 0.127 0.000
M70-M79 Other soft tissue disorders
0.872 0.128 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.872 0.128 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.870 0.130 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.865 0.135 0.000
C64-C68 Malignant neoplasms of urinary tract
0.865 0.135 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.863 0.137 0.000
C51-C58 Malignant neoplasms of female genital organs
0.862 0.138 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.862 0.138 0.000
I44 Atrioventricular and left bundle-branch block
0.860 0.140 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.860 0.140 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.858 0.142 0.000
E10-E14 Diabetes mellitus
0.855 0.145 0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified
0.853 0.147 0.000
L40.5 Arthropathic psoriasis
0.852 0.148 0.000
Chapter X Diseases of the respiratory system
0.851 0.149 0.000
F17.1 Harmful use
0.849 0.151 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.846 0.154 0.000
I38 Endocarditis, valve unspecified
0.845 0.155 0.000
K66.0 Peritoneal adhesions
0.845 0.155 0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified
0.834 0.166 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.834 0.166 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.833 0.167 0.000
Z74 Problems related to care-provider dependency
0.832 0.168 0.000
I65.2 Occlusion and stenosis of carotid artery
0.828 0.172 0.000
W00-W19 Falls
0.827 0.173 0.000
K08 Other disorders of teeth and supporting structures
0.827 0.173 0.000
K35 Acute appendicitis
0.825 0.175 0.000
K82 Other diseases of gallbladder
0.825 0.175 0.000
Y40 Systemic antibiotics
0.824 0.176 0.000
I67.2 Cerebral atherosclerosis
0.821 0.179 0.000
L50-L54 Urticaria and erythema
0.819 0.181 0.000
C50.4 Upper-outer quadrant of breast
0.818 0.182 0.000
Z51 Other medical care
0.817 0.183 0.000
L40.9 Psoriasis, unspecified
0.817 0.183 0.000
I67.9 Cerebrovascular disease, unspecified
0.817 0.183 0.000
K83.8 Other specified diseases of biliary tract
0.816 0.184 0.000
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified
0.814 0.186 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.813 0.187 0.000
S42 Fracture of shoulder and upper arm
0.812 0.188 0.000
Chapter XXII Codes for special purposes
0.812 0.188 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.810 0.190 0.000
Z72.2 Drug use
0.809 0.191 0.000
H30-H36 Disorders of choroid and retina
0.808 0.191 0.000
D00-D09 In situ neoplasms
0.808 0.192 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.806 0.194 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.804 0.196 0.000
G30-G32 Other degenerative diseases of the nervous system
0.803 0.196 0.000
M65-M68 Disorders of synovium and tendon
0.803 0.197 0.000
K14.8 Other diseases of tongue
0.803 0.197 0.000
I33 Acute and subacute endocarditis
0.803 0.197 0.000
C80 Malignant neoplasm without specification of site
0.803 0.197 0.000
M86-M90 Other osteopathies
0.801 0.198 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.801 0.199 0.000
K80 Cholelithiasis
0.799 0.201 0.000
T85.4 Mechanical complication of breast prosthesis and implant
0.799 0.201 0.000
Z50.2 Alcohol rehabilitation
0.798 0.202 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.797 0.203 0.000
F80-F89 Disorders of psychological development
0.796 0.204 0.000
K80.2 Calculus of gallbladder without cholecystitis
0.794 0.206 0.000
M72 Fibroblastic disorders
0.794 0.206 0.000
K06 Other disorders of gingiva and edentulous alveolar ridge
0.794 0.206 0.000
F60-F69 Disorders of adult personality and behaviour
0.794 0.206 0.000
S70-S79 Injuries to the hip and thigh
0.792 0.208 0.000
F29 Unspecified nonorganic psychosis
0.792 0.208 0.000
F20.0 Paranoid schizophrenia
0.790 0.210 0.000
C15 Malignant neoplasm of oesophagus
0.789 0.211 0.000
E65-E68 Obesity and other hyperalimentation
0.789 0.211 0.000
C79.6 Secondary malignant neoplasm of ovary
0.789 0.211 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.788 0.212 0.000
J09-J18 Influenza and pneumonia
0.787 0.213 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.784 0.216 0.000
H25-H28 Disorders of lens
0.783 0.217 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.783 0.217 0.000
I42 Cardiomyopathy
0.782 0.218 0.000
X20-X29 Contact with venomous animals and plants
0.781 0.219 0.000
M84 Disorders of continuity of bone
0.780 0.220 0.000
Y43 Primarily systemic agents
0.779 0.221 0.000
F30-F39 Mood [affective] disorders
0.778 0.222 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.776 0.224 0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.776 0.224 0.000
M54.56 Low back pain (Lumbar region)
0.776 0.224 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.776 0.224 0.000
L89 Decubitus ulcer
0.775 0.225 0.000
C18.2 Ascending colon
0.775 0.225 0.000
E40-E46 Malnutrition
0.774 0.226 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.773 0.227 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.772 0.228 0.000
I44.7 Left bundle-branch block, unspecified
0.772 0.228 0.000
I05-I09 Chronic rheumatic heart diseases
0.771 0.229 0.000
I67.1 Cerebral aneurysm, nonruptured
0.770 0.230 0.000
C34 Malignant neoplasm of bronchus and lung
0.769 0.231 0.000
Z47.8 Other specified orthopaedic follow-up care
0.769 0.231 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.769 0.231 0.000
S20-S29 Injuries to the thorax
0.768 0.232 0.000
L28 Lichen simplex chronicus and prurigo
0.767 0.233 0.000
R26.0 Ataxic gait
0.766 0.234 0.000
M54.2 Cervicalgia
0.766 0.234 0.000
Z47.0 Follow-up care involving removal of fracture plate and other internal fixation device
0.764 0.236 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.763 0.237 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.762 0.238 0.000
H43-H45 Disorders of vitreous body and globe
0.762 0.238 0.000
R93.1 Abnormal findings on diagnostic imaging of heart and coronary circulation
0.761 0.239 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.761 0.239 0.000
X60-X84 Intentional self-harm
0.761 0.239 0.000
E07 Other disorders of thyroid
0.760 0.240 0.000
M54.50 Low back pain (Multiple sites in spine)
0.759 0.241 0.000
L29 Pruritus
0.759 0.241 0.000
M60-M63 Disorders of muscles
0.756 0.244 0.000
M91-M94 Chondropathies
0.755 0.245 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.755 0.245 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.755 0.245 0.000
W20-W49 Exposure to inanimate mechanical forces
0.753 0.247 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.753 0.247 0.000
C54 Malignant neoplasm of corpus uteri
0.753 0.247 0.000
Y40.0 Penicillins
0.753 0.247 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.753 0.247 0.000
E06 Thyroiditis
0.752 0.247 0.000
L60-L75 Disorders of skin appendages
0.750 0.250 0.000
K08.3 Retained dental root
0.749 0.251 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.749 0.251 0.000
J40-J47 Chronic lower respiratory diseases
0.749 0.251 0.000
Chapter VIII Diseases of the ear and mastoid process
0.749 0.251 0.000
E11 Non-insulin-dependent diabetes mellitus
0.749 0.251 0.000
R00 Abnormalities of heart beat
0.749 0.251 0.000
M54.1 Radiculopathy
0.748 0.252 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.747 0.253 0.000
I44.1 Atrioventricular block, second degree
0.747 0.253 0.000
M53 Other dorsopathies, not elsewhere classified
0.747 0.253 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.747 0.253 0.000
S42.2 Fracture of upper end of humerus
0.746 0.254 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.746 0.254 0.000
K13.6 Irritative hyperplasia of oral mucosa
0.746 0.254 0.000
K07 Dentofacial anomalies [including malocclusion]
0.744 0.256 0.000
H02 Other disorders of eyelid
0.744 0.256 0.000
M81 Osteoporosis without pathological fracture
0.744 0.256 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.743 0.257 0.000
H10-H13 Disorders of conjunctiva
0.742 0.258 0.000
C16 Malignant neoplasm of stomach
0.742 0.258 0.000
C79.2 Secondary malignant neoplasm of skin
0.741 0.259 0.000
Y52 Agents primarily affecting the cardiovascular system
0.741 0.259 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.740 0.260 0.000
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care
0.740 0.260 0.000
E20-E35 Disorders of other endocrine glands
0.739 0.260 0.000
K83.1 Obstruction of bile duct
0.739 0.261 0.000
V20-V29 Motorcycle rider injured in transport accident
0.738 0.262 0.000
M72.0 Palmar fascial fibromatosis [Dupuytren]
0.737 0.263 0.000
C50.8 Overlapping lesion of breast
0.737 0.263 0.000
I36 Nonrheumatic tricuspid valve disorders
0.736 0.264 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.736 0.264 0.000
I61 Intracerebral haemorrhage
0.736 0.264 0.000
R21 Rash and other nonspecific skin eruption
0.736 0.264 0.000
F22 Persistent delusional disorders
0.736 0.264 0.000
V80-V89 Other land transport accidents
0.735 0.265 0.000
R27 Other lack of coordination
0.734 0.266 0.000
T83.1 Mechanical complication of other urinary devices and implants
0.734 0.266 0.000
C18.3 Hepatic flexure
0.734 0.266 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.734 0.266 0.000
M45-M49 Spondylopathies
0.732 0.268 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.732 0.268 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.731 0.269 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.731 0.269 0.000
I50.9 Heart failure, unspecified
0.730 0.270 0.000
Z51.0 Radiotherapy session
0.730 0.270 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.730 0.270 0.000
H34 Retinal vascular occlusions
0.730 0.270 0.000
S90-S99 Injuries to the ankle and foot
0.728 0.272 0.000
L21 Seborrhoeic dermatitis
0.728 0.272 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.727 0.273 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.727 0.273 0.000
M54.3 Sciatica
0.727 0.273 0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.726 0.274 0.000
Z48 Other surgical follow-up care
0.725 0.275 0.000
H25 Senile cataract
0.725 0.275 0.000
C55 Malignant neoplasm of uterus, part unspecified
0.725 0.275 0.000
Z74.0 Reduced mobility
0.725 0.275 0.000
J44 Other chronic obstructive pulmonary disease
0.724 0.276 0.000
E53 Deficiency of other B group vitamins
0.724 0.276 0.000
S32 Fracture of lumbar spine and pelvis
0.724 0.276 0.000
T79-T79 Certain early complications of trauma
0.723 0.276 0.000
I44.3 Other and unspecified atrioventricular block
0.723 0.277 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.723 0.277 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.723 0.277 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.723 0.277 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.723 0.277 0.000
R00.2 Palpitations
0.721 0.279 0.000
K35.8 Acute appendicitis, other and unspecified
0.720 0.280 0.000
Y83.2 Surgical operation with anastomosis, bypass or graft
0.720 0.280 0.000
K11 Diseases of salivary glands
0.720 0.280 0.000
J18 Pneumonia, organism unspecified
0.720 0.280 0.000
M80 Osteoporosis with pathological fracture
0.720 0.280 0.000
I60 Subarachnoid haemorrhage
0.720 0.280 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.719 0.280 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.718 0.282 0.000
I34 Nonrheumatic mitral valve disorders
0.718 0.282 0.000
C34.9 Bronchus or lung, unspecified
0.718 0.282 0.000
I69 Sequelae of cerebrovascular disease
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.717 0.283 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.717 0.283 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.717 0.283 0.000
R03 Abnormal blood-pressure reading, without diagnosis
0.717 0.283 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.716 0.283 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.716 0.283 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.716 0.284 0.000
L90 Atrophic disorders of skin
0.716 0.284 0.000
E55 Vitamin D deficiency
0.715 0.285 0.000
H40-H42 Glaucoma
0.715 0.285 0.000
L10-L14 Bullous disorders
0.714 0.286 0.000
T33-T35 Frostbite
0.714 0.286 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.714 0.286 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.714 0.286 0.000
T00-T07 Injuries involving multiple body regions
0.714 0.286 0.000
S10-S19 Injuries to the neck
0.714 0.286 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.713 0.286 0.000
Y35-Y36 Legal intervention and operations of war
0.713 0.286 0.000
Y10-Y34 Event of undetermined intent
0.713 0.286 0.000
Y00-Y09 Assault
0.713 0.286 0.000
X85-X99 Assault
0.713 0.286 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.713 0.286 0.000
X50-X57 Overexertion, travel and privation
0.713 0.286 0.000
X30-X39 Exposure to forces of nature
0.713 0.286 0.000
X10-X19 Contact with heat and hot substances
0.713 0.286 0.000
X00-X09 Exposure to smoke, fire and flames
0.713 0.286 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.713 0.286 0.000
W75-W84 Other accidental threats to breathing
0.713 0.286 0.000
W65-W74 Accidental drowning and submersion
0.713 0.286 0.000
W50-W64 Exposure to animate mechanical forces
0.713 0.286 0.000
V98-V99 Other and unspecified transport accidents
0.713 0.286 0.000
V95-V97 Air and space transport accidents
0.713 0.286 0.000
V90-V94 Water transport accidents
0.713 0.286 0.000
V70-V79 Bus occupant injured in transport accident
0.713 0.286 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.713 0.286 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.713 0.286 0.000
V40-V49 Car occupant injured in transport accident
0.713 0.286 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.713 0.286 0.000
V01-V09 Pedestrian injured in transport accident
0.713 0.286 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.713 0.287 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.712 0.288 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.712 0.288 0.000
F70-F79 Mental retardation
0.712 0.288 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.712 0.288 0.000
M54.4 Lumbago with sciatica
0.712 0.288 0.000
C50.0 Nipple and areola
0.711 0.289 0.000
C77.2 Intra-abdominal lymph nodes
0.711 0.289 0.000
M00-M03 Infectious arthropathies
0.710 0.290 0.000
V10-V19 Pedal cyclist injured in transport accident
0.710 0.290 0.000
R93.7 Abnormal findings on diagnostic imaging of other parts of musculoskeletal system
0.709 0.291 0.000
T86 Failure and rejection of transplanted organs and tissues
0.708 0.292 0.000
Y84.2 Radiological procedure and radiotherapy
0.708 0.292 0.000
R29.4 Clicking hip
0.708 0.292 0.000
R29.3 Abnormal posture
0.708 0.292 0.000
R29.2 Abnormal reflex
0.708 0.292 0.000
R29.1 Meningismus
0.708 0.292 0.000
R29.0 Tetany
0.708 0.292 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.707 0.292 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.706 0.294 0.000
Z76 Persons encountering health services in other circumstances
0.705 0.295 0.000
Z70 Counselling related to sexual attitude, behaviour and orientation
0.705 0.295 0.000
M79.8 Other specified soft tissue disorders
0.705 0.295 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.703 0.297 0.000
C50.3 Lower-inner quadrant of breast
0.702 0.297 0.000
I52 Other heart disorders in diseases classified elsewhere
0.702 0.298 0.000
I48 Atrial fibrillation and flutter
0.702 0.298 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.702 0.298 0.000
I41 Myocarditis in diseases classified elsewhere
0.702 0.298 0.000
I40 Acute myocarditis
0.702 0.298 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.702 0.298 0.000
I37 Pulmonary valve disorders
0.702 0.298 0.000
I32 Pericarditis in diseases classified elsewhere
0.702 0.298 0.000
I30 Acute pericarditis
0.702 0.298 0.000
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system
0.702 0.298 0.000
L53 Other erythematous conditions
0.701 0.299 0.000
F25 Schizoaffective disorders
0.700 0.300 0.000
F23 Acute and transient psychotic disorders
0.700 0.300 0.000
F28 Other nonorganic psychotic disorders
0.700 0.300 0.000
F24 Induced delusional disorder
0.700 0.300 0.000
F21 Schizotypal disorder
0.700 0.300 0.000
S42.20 Fracture of upper end of humerus (closed)
0.699 0.301 0.000
K10 Other diseases of jaws
0.698 0.302 0.000
S80-S89 Injuries to the knee and lower leg
0.698 0.302 0.000
M72.04 Palmar fascial fibromatosis [Dupuytren]-Hand
0.697 0.303 0.000
Z72.9 Problem related to lifestyle, unspecified
0.696 0.304 0.000
Z72.8 Other problems related to lifestyle
0.696 0.304 0.000
Z72.6 Gambling and betting
0.696 0.304 0.000
Z72.5 High-risk sexual behaviour
0.696 0.304 0.000
Z72.4 Inappropriate diet and eating habits
0.696 0.304 0.000
Z72.3 Lack of physical exercise
0.696 0.304 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.696 0.304 0.000
K09 Cysts of oral region, not elsewhere classified
0.696 0.304 0.000
K03 Other diseases of hard tissues of teeth
0.696 0.304 0.000
K00 Disorders of tooth development and eruption
0.696 0.304 0.000
R92 Abnormal findings on diagnostic imaging of breast
0.696 0.304 0.000
I77 Other disorders of arteries and arterioles
0.696 0.304 0.000
Z54 Convalescence
0.695 0.305 0.000
Z44 Fitting and adjustment of external prosthetic device
0.695 0.305 0.000
H20 Iridocyclitis
0.695 0.305 0.000
T39.1 4-Aminophenol derivatives
0.695 0.305 0.000
C77.0 Lymph nodes of head, face and neck
0.693 0.307 0.000
I62 Other nontraumatic intracranial haemorrhage
0.692 0.308 0.000
I63.8 Other cerebral infarction
0.692 0.308 0.000
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.692 0.308 0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.692 0.308 0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.692 0.308 0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.692 0.308 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.691 0.309 0.000
F33 Recurrent depressive disorder
0.690 0.310 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.690 0.310 0.000
M54.57 Low back pain (Lumbosacral region)
0.689 0.311 0.000
Z50.6 Orthoptic training
0.689 0.311 0.000
Z50.4 Psychotherapy, not elsewhere classified
0.689 0.311 0.000
Z50.3 Drug rehabilitation
0.689 0.311 0.000
L92 Granulomatous disorders of skin and subcutaneous tissue
0.689 0.311 0.000
M54.8 Other dorsalgia
0.689 0.311 0.000
M54.6 Pain in thoracic spine
0.689 0.311 0.000
M54.0 Panniculitis affecting regions of neck and back
0.689 0.311 0.000
Z71.1 Person with feared complaint in whom no diagnosis is made
0.688 0.312 0.000
Z50.5 Speech therapy
0.687 0.313 0.000
M40-M43 Deforming dorsopathies
0.687 0.313 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.687 0.313 0.000
F20.8 Other schizophrenia
0.686 0.314 0.000
F20.6 Simple schizophrenia
0.686 0.314 0.000
F20.5 Residual schizophrenia
0.686 0.314 0.000
F20.4 Postschizophrenic depression
0.686 0.314 0.000
F20.3 Undifferentiated schizophrenia
0.686 0.314 0.000
F20.2 Catatonic schizophrenia
0.686 0.314 0.000
F20.1 Hebephrenic schizophrenia
0.686 0.314 0.000
K35.9 Acute appendicitis, unspecified
0.686 0.314 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.685 0.315 0.000
Z50.8 Care involving use of rehabilitation procedures
0.685 0.315 0.000
K13.2 Leukoplakia and other disturbances of oral epithelium, including tongue
0.685 0.315 0.000
K13.5 Oral submucous fibrosis
0.685 0.315 0.000
K13.4 Granuloma and granuloma-like lesions of oral mucosa
0.685 0.315 0.000
K13.3 Hairy leukoplakia
0.685 0.315 0.000
K13.1 Cheek and lip biting
0.685 0.315 0.000
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified
0.685 0.315 0.000
J43 Emphysema
0.685 0.315 0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.684 0.316 0.000
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.683 0.317 0.000
L95 Vasculitis limited to skin, not elsewhere classified
0.683 0.317 0.000
L94 Other localised connective tissue disorders
0.683 0.317 0.000
L93 Lupus erythematosus
0.683 0.317 0.000
L87 Transepidermal elimination disorders
0.683 0.317 0.000
L88 Pyoderma gangrenosum
0.683 0.317 0.000
L86 Keratoderma in diseases classified elsewhere
0.683 0.317 0.000
L83 Acanthosis nigricans
0.683 0.317 0.000
L80 Vitiligo
0.683 0.317 0.000
Z71.8 Other specified counselling
0.683 0.317 0.000
C77.8 Lymph nodes of multiple regions
0.682 0.318 0.000
S40 Superficial injury of shoulder and upper arm
0.682 0.318 0.000
C15.5 Lower third of oesophagus
0.681 0.319 0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts
0.680 0.320 0.000
G20-G26 Extrapyramidal and movement disorders
0.680 0.320 0.000
M54.55 Low back pain (Thoracolumbar region)
0.679 0.321 0.000
M54.54 Low back pain-Thoracic
0.679 0.321 0.000
M54.53 Low back pain-Cervicothoracic
0.679 0.321 0.000
M54.52 Low back pain-Cervical
0.679 0.321 0.000
M54.51 Low back pain-Occipit-atl-axl
0.679 0.321 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.678 0.322 0.000
T87 Complications peculiar to reattachment and amputation
0.678 0.322 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.678 0.322 0.000
K82.4 Cholesterolosis of gallbladder
0.678 0.322 0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)
0.677 0.322 0.000
K14.0 Glossitis
0.677 0.323 0.000
I67.7 Cerebral arteritis, not elsewhere classified
0.677 0.323 0.000
I67.6 Nonpyogenic thrombosis of intracranial venous system
0.677 0.323 0.000
I67.5 Moyamoya disease
0.677 0.323 0.000
I67.4 Hypertensive encephalopathy
0.677 0.323 0.000
I67.3 Progressive vascular leukoencephalopathy
0.677 0.323 0.000
I67.0 Dissection of cerebral arteries, nonruptured
0.677 0.323 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.677 0.323 0.000
H25.8 Other senile cataract
0.676 0.324 0.000
I33.0 Acute and subacute infective endocarditis
0.676 0.324 0.000
E13 Other specified diabetes mellitus
0.676 0.324 0.000
L27 Dermatitis due to substances taken internally
0.676 0.324 0.000
R25 Abnormal involuntary movements
0.676 0.324 0.000
L44 Other papulosquamous disorders
0.675 0.325 0.000
L41 Parapsoriasis
0.675 0.325 0.000
L45 Papulosquamous disorders in diseases classified elsewhere
0.675 0.325 0.000
L42 Pityriasis rosea
0.675 0.325 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.675 0.325 0.000
R26.3 Immobility
0.675 0.325 0.000
R26.2 Difficulty in walking, not elsewhere classified
0.675 0.325 0.000
R26.1 Paralytic gait
0.675 0.325 0.000
K86 Other diseases of pancreas
0.674 0.325 0.000
C54.1 Endometrium
0.674 0.325 0.000
M85 Other disorders of bone density and structure
0.674 0.326 0.000
Chapter I Certain infectious and parasitic diseases
0.674 0.326 0.000
C67 Malignant neoplasm of bladder
0.674 0.326 0.000
C18.6 Descending colon
0.674 0.326 0.000
I67.8 Other specified cerebrovascular diseases
0.673 0.327 0.000
I10-I15 Hypertensive diseases
0.673 0.327 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.673 0.327 0.000
C21 Malignant neoplasm of anus and anal canal
0.673 0.327 0.000
C17 Malignant neoplasm of small intestine
0.673 0.327 0.000
C23 Malignant neoplasm of gallbladder
0.673 0.327 0.000
Z40 Prophylactic surgery
0.673 0.327 0.000
K65 Peritonitis
0.672 0.328 0.000
J60-J70 Lung diseases due to external agents
0.672 0.328 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.670 0.330 0.000
I35 Nonrheumatic aortic valve disorders
0.668 0.332 0.000
M77 Other enthesopathies
0.668 0.332 0.000
K35.1 Acute appendicitis with peritoneal abscess
0.668 0.332 0.000
E04 Other non-toxic goitre
0.668 0.332 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.667 0.333 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.667 0.333 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.667 0.333 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.667 0.333 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.667 0.333 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.667 0.333 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.667 0.333 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.667 0.333 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.667 0.333 0.000
T36 Poisoning by systemic antibiotics
0.667 0.333 0.000
K06.8 Other specified disorders of gingiva and edentulous alveolar ridge
0.667 0.333 0.000
C18.5 Splenic flexure
0.666 0.334 0.000
R23 Other skin changes
0.666 0.334 0.000
I42.8 Other cardiomyopathies
0.666 0.334 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.666 0.334 0.000
E61 Deficiency of other nutrient elements
0.666 0.334 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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