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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs112374545
log Bayes Factor = 78.2181
Chromosome 19   position 11,188,899  (GRCh37) Explore rs112374545 on Ensembl!
Variant rs112374545 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E78.0 Pure hypercholesterolaemia
0.000 0.000 1.000
I20.9 Angina pectoris, unspecified
0.000 0.000 1.000
I25.1 Atherosclerotic heart disease
0.000 0.000 1.000
I25 Chronic ischaemic heart disease
0.000 0.000 1.000
I20 Angina pectoris
0.000 0.000 1.000
I20-I25 Ischaemic heart diseases
0.000 0.000 1.000
Z95.1 Presence of aortocoronary bypass graft
0.000 0.000 1.000
I21 Acute myocardial infarction
0.000 0.000 1.000
I25.9 Chronic ischaemic heart disease, unspecified
0.000 0.000 1.000
I25.2 Old myocardial infarction
0.000 0.000 1.000
Z95.5 Presence of coronary angioplasty implant and graft
0.000 0.000 1.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.000 0.000 1.000
Z95 Presence of cardiac and vascular implants and grafts
0.000 0.001 0.999
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.003 0.997
E78.5 Hyperlipidaemia, unspecified
0.000 0.007 0.993
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.007 0.993
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.017 0.983
I71 Aortic aneurysm and dissection
0.000 0.020 0.980
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.000 0.021 0.979
I20.0 Unstable angina
0.000 0.022 0.978
Chapter IX Diseases of the circulatory system
0.000 0.027 0.973
I73 Other peripheral vascular diseases
0.000 0.032 0.968
I21.0 Acute transmural myocardial infarction of anterior wall
0.000 0.060 0.940
I22 Subsequent myocardial infarction
0.000 0.061 0.939
I73.9 Peripheral vascular disease, unspecified
0.000 0.070 0.930
I21.9 Acute myocardial infarction, unspecified
0.000 0.083 0.917
I73.0 Raynaud's syndrome
0.000 0.094 0.906
I25.3 Aneurysm of heart
0.000 0.116 0.884
I20.8 Other forms of angina pectoris
0.000 0.118 0.882
I05-I09 Chronic rheumatic heart diseases
0.000 0.121 0.879
I21.3 Acute transmural myocardial infarction of unspecified site
0.000 0.134 0.866
I77 Other disorders of arteries and arterioles
0.000 0.140 0.860
I08 Multiple valve diseases
0.000 0.143 0.857
I24 Other acute ischaemic heart diseases
0.000 0.154 0.846
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.155 0.845
Z95.8 Presence of other cardiac and vascular implants and grafts
0.000 0.162 0.838
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.000 0.164 0.836
I20.1 Angina pectoris with documented spasm
0.000 0.171 0.829
I22.8 Subsequent myocardial infarction of other sites
0.000 0.177 0.823
I71.3 Abdominal aortic aneurysm, ruptured
0.000 0.185 0.815
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.000 0.187 0.813
I77.1 Stricture of artery
0.000 0.196 0.804
I21.4 Acute subendocardial myocardial infarction
0.000 0.217 0.783
E78.8 Other disorders of lipoprotein metabolism
0.000 0.238 0.762
I72 Other aneurysm
0.000 0.240 0.760
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.240 0.760
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.267 0.733
I25.5 Ischaemic cardiomyopathy
0.000 0.276 0.724
I21.X Presumed acute myicardial infaction (unconfirmed)
0.000 0.283 0.717
I25.6 Silent myocardial ischaemia
0.000 0.283 0.717
I23 Certain current complications following acute myocardial infarction
0.000 0.283 0.717
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.286 0.714
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.287 0.713
E78.6 Lipoprotein deficiency
0.000 0.288 0.712
E78.3 Hyperchylomicronaemia
0.000 0.288 0.712
I08.1 Disorders of both mitral and tricuspid valves
0.000 0.294 0.706
I71.8 Aortic aneurysm of unspecified site, ruptured
0.000 0.297 0.703
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.000 0.297 0.703
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.000 0.297 0.703
I71.1 Thoracic aortic aneurysm, ruptured
0.000 0.297 0.703
I08.8 Other multiple valve diseases
0.000 0.301 0.699
I00-I02 Acute rheumatic fever
0.000 0.303 0.697
I74 Arterial embolism and thrombosis
0.000 0.304 0.696
I73.1 Thromboangiitis obliterans [Buerger]
0.000 0.306 0.694
I77.0 Arteriovenous fistula, acquired
0.000 0.306 0.694
I72.4 Aneurysm of artery of lower extremity
0.000 0.313 0.687
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.318 0.682
E78.2 Mixed hyperlipidaemia
0.000 0.323 0.676
E78.1 Pure hyperglyceridaemia
0.000 0.336 0.664
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.000 0.340 0.660
I08.0 Disorders of both mitral and aortic valves
0.000 0.341 0.658
I73.8 Other specified peripheral vascular diseases
0.000 0.349 0.651
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.354 0.646
I07 Rheumatic tricuspid valve diseases
0.000 0.363 0.637
I06 Rheumatic aortic valve diseases
0.000 0.369 0.630
I30-I52 Other forms of heart disease
0.000 0.372 0.628
I70 Atherosclerosis
0.000 0.383 0.617
I77.5 Necrosis of artery
0.000 0.384 0.616
I77.4 Coeliac artery compression syndrome
0.000 0.384 0.616
I77.3 Arterial fibromuscular dysplasia
0.000 0.384 0.616
I77.2 Rupture of artery
0.000 0.384 0.616
I08.9 Multiple valve disease, unspecified
0.000 0.385 0.614
I25.4 Coronary artery aneurysm
0.000 0.386 0.614
Z95.2 Presence of prosthetic heart valve
0.000 0.387 0.613
I38 Endocarditis, valve unspecified
0.000 0.390 0.610
E78.4 Other hyperlipidaemia
0.000 0.392 0.607
I24.1 Dressler's syndrome
0.000 0.393 0.606
Z95.3 Presence of xenogenic heart valve
0.000 0.397 0.603
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.000 0.399 0.601
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.000 0.399 0.601
I78 Diseases of capillaries
0.000 0.401 0.599
I08.2 Disorders of both aortic and tricuspid valves
0.000 0.409 0.591
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.000 0.417 0.583
I09 Other rheumatic heart diseases
0.000 0.421 0.579
I77.8 Other specified disorders of arteries and arterioles
0.000 0.437 0.563
I77.9 Disorder of arteries and arterioles, unspecified
0.000 0.440 0.560
I35 Nonrheumatic aortic valve disorders
0.000 0.441 0.559
I49 Other cardiac arrhythmias
0.000 0.448 0.552
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.452 0.548
I72.6 Aneurysm and dissection of vertebral artery
0.000 0.455 0.545
I72.5 Aneurysm and dissection of other precerebral arteries
0.000 0.455 0.545
I72.2 Aneurysm of renal artery
0.000 0.455 0.545
I72.1 Aneurysm of artery of upper extremity
0.000 0.455 0.545
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.455 0.545
I79.1 Aortitis in diseases classified elsewhere
0.000 0.455 0.545
I79.0 Aneurysm of aorta in diseases classified elsewhere
0.000 0.455 0.545
I95-I99 Other and unspecified disorders of the circulatory system
0.000 0.460 0.540
I72.3 Aneurysm of iliac artery
0.000 0.466 0.534
I74.8 Embolism and thrombosis of other arteries
0.000 0.474 0.526
I72.9 Aneurysm of unspecified site
0.000 0.480 0.520
I35.0 Aortic (valve) stenosis
0.000 0.482 0.518
I23.8 Other current complications following acute myocardial infarction
0.000 0.486 0.514
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.000 0.486 0.514
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.000 0.486 0.514
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.000 0.486 0.514
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.000 0.486 0.514
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.000 0.486 0.514
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.000 0.486 0.514
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.000 0.486 0.514
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.000 0.489 0.511
I71.0 Dissection of aorta [any part]
0.000 0.499 0.500
I02 Rheumatic chorea
0.000 0.500 0.500
I01 Rheumatic fever with heart involvement
0.000 0.500 0.500
I00 Rheumatic fever without mention of heart involvement
0.000 0.500 0.500
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.000 0.501 0.499
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.000 0.501 0.499
I49.0 Ventricular fibrillation and flutter
0.000 0.501 0.499
I30 Acute pericarditis
0.000 0.508 0.492
Z95.0 Presence of cardiac pacemaker
0.000 0.514 0.486
I77.6 Arteritis, unspecified
0.000 0.514 0.486
I72.8 Aneurysm of other specified arteries
0.000 0.518 0.481
I47 Paroxysmal tachycardia
0.000 0.521 0.479
I49.8 Other specified cardiac arrhythmias
0.000 0.523 0.477
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.000 0.525 0.475
I21.2 Acute transmural myocardial infarction of other sites
0.000 0.526 0.474
I44 Atrioventricular and left bundle-branch block
0.000 0.533 0.467
I07.1 Tricuspid insufficiency
0.000 0.536 0.464
I99 Other and unspecified disorders of circulatory system
0.000 0.540 0.460
I07.9 Tricuspid valve disease, unspecified
0.000 0.543 0.457
I07.8 Other tricuspid valve diseases
0.000 0.543 0.457
I07.2 Tricuspid stenosis with insufficiency
0.000 0.543 0.457
I07.0 Tricuspid stenosis
0.000 0.543 0.457
I72.0 Aneurysm of carotid artery
0.000 0.544 0.456
I06.9 Rheumatic aortic valve disease, unspecified
0.000 0.548 0.452
I06.8 Other rheumatic aortic valve diseases
0.000 0.548 0.452
I06.2 Rheumatic aortic stenosis with insufficiency
0.000 0.548 0.452
I06.1 Rheumatic aortic insufficiency
0.000 0.548 0.452
I06.0 Rheumatic aortic stenosis
0.000 0.548 0.452
I74.0 Embolism and thrombosis of abdominal aorta
0.000 0.549 0.451
I52 Other heart disorders in diseases classified elsewhere
0.000 0.550 0.450
I48 Atrial fibrillation and flutter
0.000 0.550 0.450
I43 Cardiomyopathy in diseases classified elsewhere
0.000 0.550 0.450
I41 Myocarditis in diseases classified elsewhere
0.000 0.550 0.450
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.000 0.550 0.450
I32 Pericarditis in diseases classified elsewhere
0.000 0.550 0.450
I51 Complications and ill-defined descriptions of heart disease
0.000 0.550 0.450
I33 Acute and subacute endocarditis
0.000 0.554 0.446
I37 Pulmonary valve disorders
0.000 0.555 0.445
I70.9 Generalised and unspecified atherosclerosis
0.000 0.558 0.442
I70.8 Atherosclerosis of other arteries
0.000 0.558 0.442
I49.9 Cardiac arrhythmia, unspecified
0.000 0.559 0.441
I78.8 Other diseases of capillaries
0.000 0.560 0.440
I70.2 Atherosclerosis of arteries of the extremities
0.000 0.561 0.439
I35.2 Aortic (valve) stenosis with insufficiency
0.000 0.568 0.432
I78.9 Disease of capillaries, unspecified
0.000 0.570 0.429
I49.4 Other and unspecified premature depolarisation
0.000 0.573 0.427
I70.1 Atherosclerosis of renal artery
0.000 0.574 0.426
I40 Acute myocarditis
0.000 0.576 0.423
I24.8 Other forms of acute ischaemic heart disease
0.000 0.577 0.423
I30.9 Acute pericarditis, unspecified
0.000 0.582 0.418
I36 Nonrheumatic tricuspid valve disorders
0.000 0.583 0.417
I09.8 Other specified rheumatic heart diseases
0.000 0.585 0.415
I09.2 Chronic rheumatic pericarditis
0.000 0.585 0.415
I09.1 Rheumatic diseases of endocardium, valve unspecified
0.000 0.585 0.415
I09.0 Rheumatic myocarditis
0.000 0.585 0.415
I74.9 Embolism and thrombosis of unspecified artery
0.000 0.587 0.413
I44.7 Left bundle-branch block, unspecified
0.000 0.594 0.406
Z95.4 Presence of other heart-valve replacement
0.000 0.597 0.403
I74.5 Embolism and thrombosis of iliac artery
0.000 0.599 0.401
I49.2 Junctional premature depolarisation
0.000 0.604 0.396
I78.0 Hereditary haemorrhagic telangiectasia
0.000 0.606 0.394
I49.1 Atrial premature depolarisation
0.000 0.608 0.391
I35.1 Aortic (valve) insufficiency
0.000 0.614 0.386
I70.0 Atherosclerosis of aorta
0.000 0.618 0.382
I35.9 Aortic valve disorder, unspecified
0.000 0.618 0.382
I47.1 Supraventricular tachycardia
0.000 0.624 0.376
I47.9 Paroxysmal tachycardia, unspecified
0.000 0.627 0.373
I95 Hypotension
0.000 0.628 0.372
I35.8 Other aortic valve disorders
0.000 0.632 0.368
I51.3 Intracardiac thrombosis, not elsewhere classified
0.000 0.636 0.364
I09.9 Rheumatic heart disease, unspecified
0.000 0.636 0.364
I51.6 Cardiovascular disease, unspecified
0.000 0.640 0.360
I01.9 Acute rheumatic heart disease, unspecified
0.000 0.641 0.359
I01.8 Other acute rheumatic heart disease
0.000 0.641 0.359
I01.2 Acute rheumatic myocarditis
0.000 0.641 0.359
I01.1 Acute rheumatic endocarditis
0.000 0.641 0.359
I01.0 Acute rheumatic pericarditis
0.000 0.641 0.359
I02.9 Rheumatic chorea without heart involvement
0.000 0.641 0.359
I02.0 Rheumatic chorea with heart involvement
0.000 0.641 0.359
I78.1 Naevus, nonneoplastic
0.000 0.644 0.356
I30.8 Other forms of acute pericarditis
0.000 0.647 0.353
I30.0 Acute nonspecific idiopathic pericarditis
0.000 0.647 0.353
I51.8 Other ill-defined heart diseases
0.000 0.659 0.341
I44.2 Atrioventricular block, complete
0.000 0.660 0.340
I44.3 Other and unspecified atrioventricular block
0.000 0.663 0.337
I44.5 Left posterior fascicular block
0.000 0.665 0.335
I44.4 Left anterior fascicular block
0.000 0.665 0.335
I51.0 Cardiac septal defect, acquired
0.000 0.665 0.335
I70.20 Atherosclerosis of arteries of extremities (without gangrene)
0.000 0.666 0.334
I45 Other conduction disorders
0.000 0.666 0.334
I28 Other diseases of pulmonary vessels
0.000 0.667 0.333
I51.9 Heart disease, unspecified
0.000 0.671 0.329
I47.2 Ventricular tachycardia
0.000 0.676 0.324
I47.0 Reentry ventricular arrhythmia
0.000 0.677 0.323
I32.8 Pericarditis in other diseases classified elsewhere
0.000 0.677 0.323
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere
0.000 0.677 0.323
I32.0 Pericarditis in bacterial diseases classified elsewhere
0.000 0.677 0.323
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere
0.000 0.677 0.323
I39.4 Multiple valve disorders in diseases classified elsewhere
0.000 0.677 0.323
I39.3 Pulmonary valve disorders in diseases classified elsewhere
0.000 0.677 0.323
I39.2 Tricuspid valve disorders in diseases classified elsewhere
0.000 0.677 0.323
I39.1 Aortic valve disorders in diseases classified elsewhere
0.000 0.677 0.323
I39.0 Mitral valve disorders in diseases classified elsewhere
0.000 0.677 0.323
I41.8 Myocarditis in other diseases classified elsewhere
0.000 0.677 0.323
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere
0.000 0.677 0.323
I41.1 Myocarditis in viral diseases classified elsewhere
0.000 0.677 0.323
I41.0 Myocarditis in bacterial diseases classified elsewhere
0.000 0.677 0.323
I43.8 Cardiomyopathy in other diseases classified elsewhere
0.000 0.677 0.323
I43.2 Cardiomyopathy in nutritional diseases
0.000 0.677 0.323
I43.1 Cardiomyopathy in metabolic diseases
0.000 0.677 0.323
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere
0.000 0.677 0.323
I48.9 Atrial fibrillation and atrial flutter, unspecified
0.000 0.677 0.323
I48.4 Atypical atrial flutter
0.000 0.677 0.323
I48.3 Typical atrial flutter
0.000 0.677 0.323
I48.2 Chronic atrial fibrillation
0.000 0.677 0.323
I48.1 Persistent atrial fibrillation
0.000 0.677 0.323
I48.0 Paroxysmal atrial fibrillation
0.000 0.677 0.323
I52.8 Other heart disorders in other diseases classified elsewhere
0.000 0.677 0.323
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.677 0.323
I52.0 Other heart disorders in bacterial diseases classified elsewhere
0.000 0.677 0.323
I51.5 Myocardial degeneration
0.000 0.677 0.322
I51.2 Rupture of papillary muscle, not elsewhere classified
0.000 0.677 0.322
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.000 0.677 0.322
I44.6 Other and unspecified fascicular block
0.000 0.678 0.322
I33.9 Acute endocarditis, unspecified
0.000 0.680 0.320
I37.9 Pulmonary valve disorder, unspecified
0.000 0.681 0.319
I37.8 Other pulmonary valve disorders
0.000 0.681 0.319
I37.2 Pulmonary valve stenosis with insufficiency
0.000 0.681 0.319
I37.0 Pulmonary valve stenosis
0.000 0.681 0.319
I70.81 Atherosclerosis of other arteries (with gangrene)
0.000 0.683 0.317
I70.80 Atherosclerosis of other arteries (without gangrene)
0.000 0.683 0.317
I70.91 Generalized and unspecified atherosclerosis (with gangrene)
0.000 0.683 0.317
I70.90 Generalized and unspecified atherosclerosis (without gangrene)
0.000 0.683 0.317
I44.1 Atrioventricular block, second degree
0.000 0.684 0.316
I33.0 Acute and subacute infective endocarditis
0.000 0.685 0.315
I37.1 Pulmonary valve insufficiency
0.000 0.686 0.314
I30.1 Infective pericarditis
0.000 0.691 0.309
I95.2 Hypotension due to drugs
0.000 0.693 0.307
I70.11 Atherosclerosis of renal artery (with gangrene)
0.000 0.694 0.305
I45.2 Bifascicular block
0.000 0.694 0.305
I40.9 Acute myocarditis, unspecified
0.000 0.696 0.304
I40.8 Other acute myocarditis
0.000 0.696 0.304
I40.1 Isolated myocarditis
0.000 0.696 0.304
I95.1 Orthostatic hypotension
0.000 0.697 0.303
I31 Other diseases of pericardium
0.000 0.700 0.300
I36.9 Nonrheumatic tricuspid valve disorder, unspecified
0.000 0.701 0.299
I36.8 Other nonrheumatic tricuspid valve disorders
0.000 0.701 0.299
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency
0.000 0.701 0.299
I36.0 Nonrheumatic tricuspid (valve) stenosis
0.000 0.701 0.299
I51.4 Myocarditis, unspecified
0.000 0.706 0.294
I46 Cardiac arrest
0.000 0.711 0.289
I70.10 Atherosclerosis of renal artery (without gangrene)
0.000 0.711 0.289
I49.3 Ventricular premature depolarisation
0.000 0.711 0.288
I70.21 Atherosclerosis of arteries of extremities (with gangrene)
0.000 0.712 0.287
I26 Pulmonary embolism
0.000 0.720 0.280
I40.0 Infective myocarditis
0.000 0.722 0.277
I70.01 Atherosclerosis of aorta (with gangrene)
0.000 0.726 0.274
I10-I15 Hypertensive diseases
0.000 0.729 0.271
I95.8 Other hypotension
0.000 0.730 0.270
I95.0 Idiopathic hypotension
0.000 0.732 0.267
I36.1 Nonrheumatic tricuspid (valve) insufficiency
0.000 0.734 0.266
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.737 0.263
I44.0 Atrioventricular block, first degree
0.000 0.740 0.260
I45.9 Conduction disorder, unspecified
0.000 0.747 0.253
I05 Rheumatic mitral valve diseases
0.001 0.750 0.248
I27 Other pulmonary heart diseases
0.000 0.757 0.243
I98 Other disorders of circulatory system in diseases classified elsewhere
0.000 0.758 0.242
I34 Nonrheumatic mitral valve disorders
0.000 0.759 0.240
I45.0 Right fascicular block
0.000 0.760 0.239
I28.9 Disease of pulmonary vessels, unspecified
0.000 0.761 0.239
I28.1 Aneurysm of pulmonary artery
0.000 0.761 0.239
I28.0 Arteriovenous fistula of pulmonary vessels
0.000 0.761 0.239
I45.8 Other specified conduction disorders
0.000 0.762 0.237
I28.8 Other specified diseases of pulmonary vessels
0.000 0.769 0.231
I49.5 Sick sinus syndrome
0.000 0.774 0.226
I31.8 Other specified diseases of pericardium
0.000 0.785 0.215
I31.2 Haemopericardium, not elsewhere classified
0.000 0.785 0.215
I31.1 Chronic constrictive pericarditis
0.000 0.785 0.215
I31.0 Chronic adhesive pericarditis
0.000 0.785 0.215
I70.00 Atherosclerosis of aorta (without gangrene)
0.000 0.786 0.214
I46.1 Sudden cardiac death, so described
0.000 0.792 0.207
I45.6 Preexcitation syndrome
0.000 0.794 0.206
I15 Secondary hypertension
0.000 0.795 0.205
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.000 0.795 0.204
I27.8 Other specified pulmonary heart diseases
0.000 0.796 0.204
I13 Hypertensive heart and renal disease
0.000 0.805 0.194
I45.5 Other specified heart block
0.000 0.805 0.194
I31.3 Pericardial effusion (noninflammatory)
0.000 0.810 0.190
I97.9 Postprocedural disorder of circulatory system, unspecified
0.000 0.811 0.189
I97.0 Postcardiotomy syndrome
0.000 0.811 0.189
I50 Heart failure
0.000 0.812 0.188
I45.3 Trifascicular block
0.000 0.812 0.188
I45.1 Other and unspecified right bundle-branch block
0.000 0.817 0.183
I05.8 Other mitral valve diseases
0.001 0.821 0.178
I46.9 Cardiac arrest, unspecified
0.000 0.821 0.179
I97.2 Postmastectomy lymphoedema syndrome
0.000 0.825 0.175
I27.1 Kyphoscoliotic heart disease
0.000 0.826 0.174
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere
0.000 0.826 0.173
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.826 0.173
I98.0 Cardiovascular syphilis
0.000 0.826 0.173
I45.4 Nonspecific intraventricular block
0.000 0.826 0.173
I34.2 Nonrheumatic mitral (valve) stenosis
0.000 0.827 0.173
I34.8 Other nonrheumatic mitral valve disorders
0.000 0.827 0.173
I27.9 Pulmonary heart disease, unspecified
0.000 0.831 0.169
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.000 0.835 0.165
I05.2 Mitral stenosis with insufficiency
0.001 0.835 0.164
I12 Hypertensive renal disease
0.000 0.841 0.159
I11 Hypertensive heart disease
0.000 0.841 0.158
I15.1 Hypertension secondary to other renal disorders
0.000 0.843 0.157
I97.1 Other functional disturbances following cardiac surgery
0.001 0.848 0.152
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified
0.001 0.848 0.151
I51.7 Cardiomegaly
0.000 0.853 0.147
I15.9 Seconday hypertension, unspecified
0.000 0.853 0.147
I15.8 Other secondary hypertension
0.000 0.853 0.147
I15.2 Hypertension secondary to endocrine disorders
0.000 0.853 0.147
I15.0 Renovascular hypertension
0.000 0.853 0.147
I27.2 Other secondary pulmonary hypertension
0.000 0.856 0.144
I34.1 Mitral (valve) prolapse
0.000 0.858 0.142
I05.0 Mitral stenosis
0.001 0.860 0.139
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.860 0.140
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.000 0.860 0.140
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.860 0.140
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.860 0.140
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.000 0.868 0.132
I50.1 Left ventricular failure
0.000 0.868 0.132
I05.9 Mitral valve disease, unspecified
0.001 0.876 0.123
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere
0.001 0.877 0.122
I98.2 Oesophageal varices in diseases classified elsewhere
0.000 0.879 0.120
I11.0 Hypertensive heart disease with (congestive) heart failure
0.000 0.880 0.119
I31.9 Disease of pericardium, unspecified
0.000 0.881 0.119
I12.0 Hypertensive renal disease with renal failure
0.000 0.885 0.115
I05.1 Rheumatic mitral insufficiency
0.002 0.885 0.113
I46.0 Cardiac arrest with successful resuscitation
0.000 0.891 0.109
I50.9 Heart failure, unspecified
0.000 0.918 0.082
I12.9 Hypertensive renal disease without renal failure
0.000 0.923 0.076
I11.9 Hypertensive heart disease without (congestive) heart failure
0.001 0.934 0.065
I95.9 Hypotension, unspecified
0.000 0.935 0.065
I34.0 Mitral (valve) insufficiency
0.000 0.935 0.065
Y83.2 Surgical operation with anastomosis, bypass or graft
0.000 0.942 0.058
I42 Cardiomyopathy
0.001 0.943 0.056
I27.0 Primary pulmonary hypertension
0.001 0.945 0.054
I42.7 Cardiomyopathy due to drugs and other external agents
0.001 0.959 0.040
I42.5 Other restrictive cardiomyopathy
0.001 0.959 0.040
I42.4 Endocardial fibroelastosis
0.001 0.959 0.040
I42.3 Endomyocardial (eosinophilic) disease
0.001 0.959 0.040
I50.0 Congestive heart failure
0.000 0.961 0.039
I42.8 Other cardiomyopathies
0.001 0.966 0.033
I42.2 Other hypertrophic cardiomyopathy
0.001 0.968 0.031
I42.0 Dilated cardiomyopathy
0.000 0.969 0.031
I42.1 Obstructive hypertrophic cardiomyopathy
0.001 0.969 0.030
I42.6 Alcoholic cardiomyopathy
0.001 0.970 0.029
I60-I69 Cerebrovascular diseases
0.000 0.970 0.029
I62 Other nontraumatic intracranial haemorrhage
0.000 0.974 0.025
I62.0 Subdural haemorrhage (acute) (nontraumatic)
0.000 0.976 0.024
O80.9 Single spontaneous delivery, unspecified
0.023 0.977 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.000 0.977 0.022
O80.0 Spontaneous vertex delivery
0.022 0.978 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.000 0.978 0.021
D17.2 Benign lipomatous neoplasm of skin and subcutaneous tissue of limbs
0.000 0.979 0.021
O80 Single spontaneous delivery
0.021 0.979 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.000 0.980 0.020
I62.1 Nontraumatic extradural haemorrhage
0.000 0.981 0.018
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.001 0.982 0.018
M13.91 Arthritis, unspecified (Shoulder region)
0.017 0.983 0.000
I65.2 Occlusion and stenosis of carotid artery
0.000 0.983 0.017
M13.97 Arthritis, unspecified (Ankle and foot)
0.017 0.983 0.000
F10.3 Withdrawal state
0.000 0.983 0.017
M13.9 Arthritis, unspecified
0.016 0.984 0.000
I65.9 Occlusion and stenosis of unspecified precerebral artery
0.000 0.984 0.016
I65.8 Occlusion and stenosis of other precerebral artery
0.000 0.984 0.016
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries
0.000 0.984 0.016
I65.1 Occlusion and stenosis of basilar artery
0.000 0.984 0.016
I65.0 Occlusion and stenosis of vertebral artery
0.000 0.984 0.016
F10.0 Acute intoxication
0.000 0.984 0.016
F10 Mental and behavioural disorders due to use of alcohol
0.000 0.984 0.016
I68.8 Other cerebrovascular disorders in diseases classified elsewhere
0.000 0.984 0.015
I68.2 Cerebral arteritis in other diseases classified elsewhere
0.000 0.984 0.015
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere
0.000 0.984 0.015
I68.0 Cerebral amyloid angiopathy
0.000 0.984 0.015
I42.9 Cardiomyopathy, unspecified
0.001 0.985 0.015
O80.1 Spontaneous breech delivery
0.015 0.985 0.000
E70-E90 Metabolic disorders
0.000 0.985 0.015
M13.94 Arthritis, unspecified (Hand)
0.015 0.985 0.000
M13.93 Arthritis, unspecified (Forearm)
0.015 0.985 0.000
F10.2 Dependence syndrome
0.000 0.985 0.015
I62.9 Intracranial haemorrhage (nontraumatic), unspecified
0.000 0.986 0.014
M50-M54 Other dorsopathies
0.014 0.986 0.000
O80.8 Other single spontaneous delivery
0.014 0.986 0.000
M50 Cervical disk disorders
0.014 0.986 0.000
M50.0 Cervical disk disorder with myelopathy
0.014 0.986 0.000
I66.8 Occlusion and stenosis of other cerebral artery
0.001 0.987 0.013
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries
0.001 0.987 0.013
I66.3 Occlusion and stenosis of cerebellar arteries
0.001 0.987 0.013
I66.2 Occlusion and stenosis of posterior cerebral artery
0.001 0.987 0.013
I66.1 Occlusion and stenosis of anterior cerebral artery
0.001 0.987 0.013
I66.0 Occlusion and stenosis of middle cerebral artery
0.001 0.987 0.013
F10.4 Withdrawal state with delirium
0.000 0.987 0.013
M51 Other intervertebral disk disorders
0.013 0.987 0.000
M54.5 Low back pain
0.013 0.987 0.000
M53 Other dorsopathies, not elsewhere classified
0.013 0.987 0.000
M13.92 Arthritis, unspecified (Upper arm)
0.013 0.987 0.000
E85 Amyloidosis
0.000 0.987 0.013
M51.2 Other specified intervertebral disk displacement
0.013 0.987 0.000
I69 Sequelae of cerebrovascular disease
0.000 0.987 0.013
M53.3 Sacrococcygeal disorders, not elsewhere classified
0.012 0.988 0.000
M54.50 Low back pain (Multiple sites in spine)
0.012 0.988 0.000
F10.9 Unspecified mental and behavioural disorder
0.000 0.988 0.012
M54.56 Low back pain (Lumbar region)
0.012 0.988 0.000
M54 Dorsalgia
0.012 0.988 0.000
M53.38 Sacrococcygeal disorders, not elsewhere classified-Sacral/s
0.012 0.988 0.000
M54.57 Low back pain (Lumbosacral region)
0.012 0.988 0.000
M13 Other arthritis
0.012 0.988 0.000
F10.8 Other mental and behavioural disorders
0.000 0.988 0.012
F10.7 Residual and late-onset psychotic disorder
0.000 0.988 0.012
F10.6 Amnesic syndrome
0.000 0.988 0.012
F10.5 Psychotic disorder
0.000 0.988 0.012
M50.2 Other cervical disk displacement
0.012 0.988 0.000
E83.5 Disorders of calcium metabolism
0.000 0.989 0.011
E84 Cystic fibrosis
0.000 0.989 0.011
E79 Disorders of purine and pyrimidine metabolism
0.000 0.989 0.011
E77 Disorders of glycoprotein metabolism
0.000 0.989 0.011
E76 Disorders of glycosaminoglycan metabolism
0.000 0.989 0.011
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.989 0.011
E72 Other disorders of amino-acid metabolism
0.000 0.989 0.011
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.989 0.011
E70 Disorders of aromatic amino-acid metabolism
0.000 0.989 0.011
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.989 0.011
E85.9 Amyloidosis, unspecified
0.000 0.989 0.011
M13.98 Arthritis, unspecified (Other)
0.011 0.989 0.000
M51.8 Other specified intervertebral disk disorders
0.011 0.989 0.000
M13.96 Arthritis, unspecified (Lower leg)
0.010 0.989 0.000
M47.99 Spondylosis, unspecified (Site unspecified)
0.010 0.990 0.000
M50.8 Other cervical disk disorders
0.010 0.990 0.000
E85.4 Organ-limited amyloidosis
0.000 0.990 0.010
M51.4 Schmorl's nodes
0.010 0.990 0.000
M50.1 Cervical disk disorder with radiculopathy
0.010 0.990 0.000
I66.9 Occlusion and stenosis of unspecified cerebral artery
0.001 0.990 0.009
M13.90 Arthritis, unspecified (Multiple sites)
0.010 0.990 0.000
M45-M49 Spondylopathies
0.010 0.990 0.000
E83 Disorders of mineral metabolism
0.000 0.990 0.010
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.990 0.010
I69.3 Sequelae of cerebral infarction
0.000 0.990 0.010
M48 Other spondylopathies
0.010 0.990 0.000
M50.3 Other cervical disk degeneration
0.010 0.990 0.000
M48.0 Spinal stenosis
0.010 0.990 0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)
0.010 0.990 0.000
M48.06 Spinal stenosis (Lumbar region)
0.010 0.990 0.000
E73 Lactose intolerance
0.000 0.990 0.010
M05-M14 Inflammatory polyarthropathies
0.010 0.990 0.000
M50.9 Cervical disk disorder, unspecified
0.010 0.990 0.000
M48.02 Spinal stenosis (Cervical region)
0.010 0.990 0.000
M51.3 Other specified intervertebral disk degeneration
0.010 0.990 0.000
M51.1 Lumbar and other intervertebral disk disorders with radiculopathy
0.010 0.990 0.000
E74 Other disorders of carbohydrate metabolism
0.000 0.990 0.009
M54.54 Low back pain-Thoracic
0.010 0.990 0.000
M54.53 Low back pain-Cervicothoracic
0.010 0.990 0.000
M54.52 Low back pain-Cervical
0.010 0.990 0.000
M54.51 Low back pain-Occipit-atl-axl
0.010 0.990 0.000
M53.9 Dorsopathy, unspecified
0.009 0.990 0.000
M53.8 Other specified dorsopathies
0.009 0.990 0.000
M53.2 Spinal instabilities
0.009 0.990 0.000
M53.1 Cervicobrachial syndrome
0.009 0.990 0.000
M53.0 Cervicocranial syndrome
0.009 0.990 0.000
M54.8 Other dorsalgia
0.010 0.990 0.000
M51.9 Intervertebral disk disorder, unspecified
0.010 0.990 0.000
E85.8 Other amyloidosis
0.000 0.990 0.009
E85.3 Secondary systemic amyloidosis
0.000 0.990 0.009
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.990 0.009
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.990 0.009
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.990 0.009
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.000 0.991 0.009
I60 Subarachnoid haemorrhage
0.001 0.991 0.009
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.009 0.991 0.000
K85.9 Acute pancreatitis, unspecified
0.009 0.991 0.000
M47 Spondylosis
0.009 0.991 0.000
M54.6 Pain in thoracic spine
0.009 0.991 0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.000 0.991 0.009
E88 Other metabolic disorders
0.000 0.991 0.009
M47.8 Other spondylosis
0.009 0.991 0.000
M53.39 Sacrococcygeal disorders, not elsewhere classified-Site uns
0.009 0.991 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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