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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs112643338
log Bayes Factor = 0.293833
Chromosome 21   position 20,128,909  (GRCh37) Explore rs112643338 on Ensembl!
Variant rs112643338 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.483 0.517 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.480 0.520 0.000
M20-M25 Other joint disorders
0.476 0.524 0.000
# Top node
0.475 0.525 0.000
M50-M54 Other dorsopathies
0.468 0.532 0.000
M25 Other joint disorders, not elsewhere classified
0.464 0.536 0.000
M20 Acquired deformities of fingers and toes
0.455 0.544 0.000
Chapter XIV Diseases of the genitourinary system
0.448 0.552 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.444 0.556 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.439 0.561 0.000
N20-N23 Urolithiasis
0.438 0.562 0.000
M25.5 Pain in joint
0.432 0.568 0.000
O60-O75 Complications of labour and delivery
0.428 0.572 0.000
S80-S89 Injuries to the knee and lower leg
0.425 0.575 0.000
N20 Calculus of kidney and ureter
0.422 0.578 0.000
M20.4 Other hammer toe(s) (acquired)
0.421 0.579 0.000
M25.7 Osteophyte
0.418 0.582 0.000
M45-M49 Spondylopathies
0.415 0.585 0.000
M54 Dorsalgia
0.414 0.586 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.408 0.592 0.000
M50 Cervical disk disorders
0.407 0.593 0.000
N20.1 Calculus of ureter
0.402 0.598 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.400 0.600 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.399 0.601 0.000
Chapter V Mental and behavioural disorders
0.398 0.602 0.000
M20.1 Hallux valgus (acquired)
0.394 0.606 0.000
M51 Other intervertebral disk disorders
0.394 0.606 0.000
S70-S79 Injuries to the hip and thigh
0.392 0.608 0.000
M25.56 Pain in joint (Lower leg)
0.390 0.610 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.385 0.615 0.000
S50-S59 Injuries to the elbow and forearm
0.385 0.615 0.000
N23 Unspecified renal colic
0.383 0.617 0.000
N00-N08 Glomerular diseases
0.381 0.619 0.000
M48 Other spondylopathies
0.380 0.620 0.000
Chapter XXII Codes for special purposes
0.379 0.621 0.000
M80-M85 Disorders of bone density and structure
0.379 0.621 0.000
S82 Fracture of lower leg, including ankle
0.378 0.622 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.378 0.622 0.000
O63 Long labour
0.378 0.622 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.375 0.625 0.000
Chapter XX External causes of morbidity and mortality
0.375 0.625 0.000
M25.78 Osteophyte (Other)
0.372 0.628 0.000
T66-T78 Other and unspecified effects of external causes
0.371 0.629 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.368 0.632 0.000
T79-T79 Certain early complications of trauma
0.367 0.632 0.000
S20-S29 Injuries to the thorax
0.367 0.633 0.000
Chapter XXI Factors influencing health status and contact with health services
0.365 0.635 0.000
M25.8 Other specified joint disorders
0.364 0.636 0.000
S40-S49 Injuries to the shoulder and upper arm
0.364 0.636 0.000
M86-M90 Other osteopathies
0.362 0.638 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.361 0.639 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.361 0.639 0.000
M53 Other dorsopathies, not elsewhere classified
0.359 0.641 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.359 0.641 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.359 0.641 0.000
M48.0 Spinal stenosis
0.356 0.644 0.000
S00-S09 Injuries to the head
0.355 0.644 0.000
M20.2 Hallux rigidus
0.354 0.646 0.000
M25.51 Pain in joint (Shoulder region)
0.354 0.646 0.000
Chapter I Certain infectious and parasitic diseases
0.352 0.648 0.000
S90-S99 Injuries to the ankle and foot
0.351 0.649 0.000
M50.3 Other cervical disk degeneration
0.350 0.650 0.000
M05-M14 Inflammatory polyarthropathies
0.350 0.650 0.000
Chapter VII Diseases of the eye and adnexa
0.349 0.651 0.000
O70 Perineal laceration during delivery
0.348 0.652 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.347 0.653 0.000
M91-M94 Chondropathies
0.346 0.654 0.000
M60-M63 Disorders of muscles
0.346 0.654 0.000
M00-M03 Infectious arthropathies
0.346 0.654 0.000
N99-N99 Other disorders of the genitourinary system
0.346 0.654 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.345 0.655 0.000
T33-T35 Frostbite
0.344 0.655 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.344 0.655 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.344 0.655 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.344 0.655 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.344 0.655 0.000
T00-T07 Injuries involving multiple body regions
0.344 0.655 0.000
S10-S19 Injuries to the neck
0.344 0.655 0.000
N20.2 Calculus of kidney with calculus of ureter
0.344 0.656 0.000
M40-M43 Deforming dorsopathies
0.343 0.657 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.342 0.658 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.342 0.658 0.000
M34 Systemic sclerosis
0.342 0.658 0.000
M33 Dermatopolymyositis
0.342 0.658 0.000
M32 Systemic lupus erythematosus
0.342 0.658 0.000
M31 Other necrotising vasculopathies
0.342 0.658 0.000
M30 Polyarteritis nodosa and related conditions
0.342 0.658 0.000
M24 Other specific joint derangements
0.342 0.658 0.000
M22 Disorders of patella
0.342 0.658 0.000
M21 Other acquired deformities of limbs
0.342 0.658 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.340 0.659 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.340 0.659 0.000
M51.2 Other specified intervertebral disk displacement
0.341 0.659 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.340 0.660 0.000
M54.4 Lumbago with sciatica
0.339 0.661 0.000
M20.6 Acquired deformity of toe(s), unspecified
0.337 0.662 0.000
D69 Purpura and other haemorrhagic conditions
0.336 0.663 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.336 0.663 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.336 0.664 0.000
M25.50 Pain in joint (Multiple sites)
0.335 0.665 0.000
M54.9 Dorsalgia, unspecified
0.335 0.665 0.000
M25.76 Osteophyte (Lower leg)
0.334 0.666 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.333 0.667 0.000
M25.9 Joint disorder, unspecified
0.332 0.667 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.332 0.667 0.000
M25.3 Other instability of joint
0.332 0.667 0.000
M25.2 Flail joint
0.332 0.667 0.000
M25.1 Fistula of joint
0.332 0.667 0.000
M25.0 Haemarthrosis
0.332 0.667 0.000
T90 Sequelae of injuries of head
0.332 0.667 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.332 0.668 0.000
Chapter VIII Diseases of the ear and mastoid process
0.331 0.669 0.000
M54.1 Radiculopathy
0.331 0.669 0.000
N03 Chronic nephritic syndrome
0.328 0.672 0.000
M65-M68 Disorders of synovium and tendon
0.328 0.672 0.000
W00-W19 Falls
0.327 0.673 0.000
M20.3 Other deformity of hallux (acquired)
0.327 0.673 0.000
M20.0 Deformity of finger(s)
0.327 0.673 0.000
O62 Abnormalities of forces of labour
0.326 0.674 0.000
N60-N64 Disorders of breast
0.324 0.676 0.000
O00-O08 Pregnancy with abortive outcome
0.323 0.677 0.000
M50.2 Other cervical disk displacement
0.322 0.678 0.000
S80 Superficial injury of lower leg
0.321 0.679 0.000
M54.5 Low back pain
0.321 0.679 0.000
O68.1 Labour and delivery complicated by meconium in amniotic fluid
0.321 0.679 0.000
M25.53 Pain in joint (Forearm)
0.320 0.680 0.000
O85-O92 Complications predominantly related to the puerperium
0.319 0.681 0.000
N10-N16 Renal tubulo-interstitial diseases
0.317 0.683 0.000
D69.6 Thrombocytopenia, unspecified
0.317 0.683 0.000
T51 Toxic effect of alcohol
0.317 0.683 0.000
A30-A49 Other bacterial diseases
0.317 0.683 0.000
S52 Fracture of forearm
0.317 0.683 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.316 0.684 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.315 0.685 0.000
T87 Complications peculiar to reattachment and amputation
0.315 0.685 0.000
T86 Failure and rejection of transplanted organs and tissues
0.315 0.685 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.315 0.685 0.000
M35 Other systemic involvement of connective tissue
0.315 0.685 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.314 0.685 0.000
N22 Calculus of urinary tract in diseases classified elsewhere
0.314 0.686 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.314 0.686 0.000
N21 Calculus of lower urinary tract
0.314 0.686 0.000
M25.4 Effusion of joint
0.313 0.687 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.313 0.687 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.313 0.687 0.000
S70 Superficial injury of hip and thigh
0.312 0.687 0.000
M48.06 Spinal stenosis (Lumbar region)
0.312 0.688 0.000
M25.57 Pain in joint (Ankle and foot)
0.310 0.690 0.000
M25.59 Pain in joint (Site unspecified)
0.310 0.690 0.000
M25.58 Pain in joint (Other)
0.310 0.690 0.000
M25.54 Pain in joint (Hand)
0.310 0.690 0.000
M25.52 Pain in joint (Upper arm)
0.310 0.690 0.000
N20.0 Calculus of kidney
0.310 0.690 0.000
O80-O84 Delivery
0.309 0.691 0.000
T82.1 Mechanical complication of cardiac electronic device
0.309 0.691 0.000
O68.8 Labour and delivery complicated by other evidence of foetal stress
0.307 0.693 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.307 0.693 0.000
O74 Complications of anaesthesia during labour and delivery
0.307 0.693 0.000
O73 Retained placenta and membranes, without haemorrhage
0.307 0.693 0.000
O71 Other obstetric trauma
0.307 0.693 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.307 0.693 0.000
O66 Other obstructed labour
0.307 0.693 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.307 0.693 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.307 0.693 0.000
O61 Failed induction of labour
0.307 0.693 0.000
O60 Preterm delivery
0.307 0.693 0.000
S82.0 Fracture of patella
0.307 0.693 0.000
O63.0 Prolonged first stage (of labour)
0.306 0.694 0.000
O63.9 Long labour, unspecified
0.306 0.694 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.306 0.694 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.306 0.694 0.000
S89 Other and unspecified injuries of lower leg
0.304 0.695 0.000
S88 Traumatic amputation of lower leg
0.304 0.695 0.000
S87 Crushing injury of lower leg
0.304 0.695 0.000
S86 Injury of muscle and tendon at lower leg level
0.304 0.695 0.000
S85 Injury of blood vessels at lower leg level
0.304 0.695 0.000
S84 Injury of nerves at lower leg level
0.304 0.695 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.304 0.695 0.000
S81 Open wound of lower leg
0.304 0.695 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.304 0.696 0.000
D80-D89 Certain disorders involving the immune mechanism
0.303 0.697 0.000
S72 Fracture of femur
0.303 0.697 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.302 0.697 0.000
N20.9 Urinary calculus, unspecified
0.302 0.698 0.000
S82.1 Fracture of upper end of tibia
0.302 0.698 0.000
T93 Sequelae of injuries of lower limb
0.302 0.698 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.302 0.698 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.301 0.698 0.000
M50.0 Cervical disk disorder with myelopathy
0.300 0.700 0.000
M25.79 Osteophyte (Site unspecified)
0.300 0.700 0.000
M25.75 Osteophyte (Pelvic region and thigh)
0.300 0.700 0.000
M25.74 Osteophyte (Hand)
0.300 0.700 0.000
M25.73 Osteophyte (Forearm)
0.300 0.700 0.000
M25.72 Osteophyte (Upper arm)
0.300 0.700 0.000
M25.71 Osteophyte (Shoulder region)
0.300 0.700 0.000
M25.70 Osteophyte (Multiple sites)
0.300 0.700 0.000
M45 Ankylosing spondylitis
0.299 0.701 0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.298 0.702 0.000
O63.1 Prolonged second stage (of labour)
0.298 0.702 0.000
M25.77 Osteophyte (Ankle and foot)
0.298 0.702 0.000
M49 Spondylopathies in diseases classified elsewhere
0.298 0.702 0.000
M46 Other inflammatory spondylopathies
0.298 0.702 0.000
M54.8 Other dorsalgia
0.297 0.703 0.000
M54.6 Pain in thoracic spine
0.297 0.703 0.000
M54.0 Panniculitis affecting regions of neck and back
0.297 0.703 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.297 0.703 0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts
0.295 0.705 0.000
M10 Gout
0.294 0.706 0.000
M48.02 Spinal stenosis (Cervical region)
0.294 0.706 0.000
M80 Osteoporosis with pathological fracture
0.293 0.707 0.000
M25.84 Other specified joint disorders (Hand)
0.293 0.707 0.000
T78 Adverse effects, not elsewhere classified
0.293 0.707 0.000
D55-D59 Haemolytic anaemias
0.292 0.708 0.000
N25-N29 Other disorders of kidney and ureter
0.292 0.708 0.000
M50.9 Cervical disk disorder, unspecified
0.292 0.708 0.000
M50.8 Other cervical disk disorders
0.292 0.708 0.000
A41 Other septicaemia
0.292 0.708 0.000
N40-N51 Diseases of male genital organs
0.291 0.709 0.000
S82.5 Fracture of medial malleolus
0.291 0.709 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.291 0.709 0.000
N03.9 Unspecified
0.290 0.710 0.000
M48.07 Spinal stenosis (Lumbosacral region)
0.290 0.710 0.000
O70.2 Third degree perineal laceration during delivery
0.290 0.710 0.000
M20.5 Other deformities of toe(s) (acquired)
0.290 0.710 0.000
S82.2 Fracture of shaft of tibia
0.290 0.710 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.289 0.711 0.000
H43-H45 Disorders of vitreous body and globe
0.288 0.712 0.000
M25.55 Pain in joint (Pelvic region and thigh)
0.288 0.712 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.287 0.713 0.000
T98 Sequelae of other and unspecified effects of external causes
0.286 0.713 0.000
T95 Sequelae of burns, corrosions and frostbite
0.286 0.713 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.286 0.713 0.000
T92 Sequelae of injuries of upper limb
0.286 0.713 0.000
T91 Sequelae of injuries of neck and trunk
0.286 0.713 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.286 0.713 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.286 0.713 0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft
0.286 0.713 0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis
0.286 0.713 0.000
T82.4 Mechanical complication of vascular dialysis catheter
0.286 0.713 0.000
T82.3 Mechanical complication of other vascular grafts
0.286 0.713 0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts
0.286 0.713 0.000
T82.0 Mechanical complication of heart valve prosthesis
0.286 0.713 0.000
F05 Delirium, not induced by alcohol and other psychoactive substances
0.286 0.714 0.000
F99-F99 Unspecified mental disorder
0.285 0.714 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.285 0.714 0.000
F80-F89 Disorders of psychological development
0.285 0.714 0.000
F70-F79 Mental retardation
0.285 0.714 0.000
F60-F69 Disorders of adult personality and behaviour
0.285 0.714 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.285 0.714 0.000
N30-N39 Other diseases of urinary system
0.285 0.715 0.000
M54.46 Lumbago with sciatica (Lumbar region)
0.285 0.715 0.000
S60-S69 Injuries to the wrist and hand
0.285 0.715 0.000
M81 Osteoporosis without pathological fracture
0.285 0.715 0.000
T90.2 Sequelae of fracture of skull and facial bones
0.284 0.715 0.000
N02 Recurrent and persistent haematuria
0.284 0.716 0.000
M54.2 Cervicalgia
0.284 0.716 0.000
M70-M79 Other soft tissue disorders
0.284 0.716 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.282 0.717 0.000
M51.3 Other specified intervertebral disk degeneration
0.282 0.718 0.000
M51.1 Lumbar and other intervertebral disk disorders with radiculopathy
0.282 0.718 0.000
M51.9 Intervertebral disk disorder, unspecified
0.282 0.718 0.000
M51.8 Other specified intervertebral disk disorders
0.282 0.718 0.000
M51.4 Schmorl's nodes
0.282 0.718 0.000
M51.0 Lumbar and other intervertebral disk disorders with myelopathy
0.282 0.718 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.282 0.718 0.000
M53.3 Sacrococcygeal disorders, not elsewhere classified
0.282 0.718 0.000
S42 Fracture of shoulder and upper arm
0.281 0.719 0.000
S79 Other and unspecified injuries of hip and thigh
0.281 0.719 0.000
S78 Traumatic amputation of hip and thigh
0.281 0.719 0.000
S77 Crushing injury of hip and thigh
0.281 0.719 0.000
S76 Injury of muscle and tendon at hip and thigh level
0.281 0.719 0.000
S75 Injury of blood vessels at hip and thigh level
0.281 0.719 0.000
S74 Injury of nerves at hip and thigh level
0.281 0.719 0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip
0.281 0.719 0.000
S71 Open wound of hip and thigh
0.281 0.719 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.280 0.720 0.000
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid
0.280 0.720 0.000
N72 Inflammatory disease of cervix uteri
0.279 0.720 0.000
O47 False labour
0.279 0.721 0.000
N17-N19 Renal failure
0.279 0.721 0.000
Z35 Supervision of high-risk pregnancy
0.278 0.722 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.278 0.722 0.000
M50.1 Cervical disk disorder with radiculopathy
0.278 0.722 0.000
T65 Toxic effect of other and unspecified substances
0.276 0.724 0.000
T63 Toxic effect of contact with venomous animals
0.276 0.724 0.000
T62 Toxic effect of other noxious substances eaten as food
0.276 0.724 0.000
T61 Toxic effect of noxious substances eaten as seafood
0.276 0.724 0.000
T60 Toxic effect of pesticides
0.276 0.724 0.000
T59 Toxic effect of other gases, fumes and vapours
0.276 0.724 0.000
T57 Toxic effect of other inorganic substances
0.276 0.724 0.000
T56 Toxic effect of metals
0.276 0.724 0.000
T54 Toxic effect of corrosive substances
0.276 0.724 0.000
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone
0.276 0.724 0.000
T52 Toxic effect of organic solvents
0.276 0.724 0.000
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants
0.276 0.724 0.000
T58 Toxic effect of carbon monoxide
0.276 0.724 0.000
T55 Toxic effect of soaps and detergents
0.276 0.724 0.000
S59 Other and unspecified injuries of forearm
0.276 0.724 0.000
S58 Traumatic amputation of forearm
0.276 0.724 0.000
S57 Crushing injury of forearm
0.276 0.724 0.000
S56 Injury of muscle and tendon at forearm level
0.276 0.724 0.000
S55 Injury of blood vessels at forearm level
0.276 0.724 0.000
S54 Injury of nerves at forearm level
0.276 0.724 0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow
0.276 0.724 0.000
S51 Open wound of forearm
0.276 0.724 0.000
S50 Superficial injury of forearm
0.276 0.724 0.000
W20-W49 Exposure to inanimate mechanical forces
0.276 0.724 0.000
S01 Open wound of head
0.275 0.725 0.000
M89 Other disorders of bone
0.275 0.725 0.000
S82.3 Fracture of lower end of tibia
0.275 0.725 0.000
M54.3 Sciatica
0.275 0.725 0.000
F10.0 Acute intoxication
0.275 0.725 0.000
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts
0.274 0.726 0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease
0.274 0.726 0.000
D68 Other coagulation defects
0.274 0.726 0.000
N60 Benign mammary dysplasia
0.274 0.726 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.273 0.727 0.000
N07 Hereditary nephropathy, not elsewhere classified
0.273 0.727 0.000
N06 Isolated proteinuria with specified morphological lesion
0.273 0.727 0.000
N05 Unspecified nephritic syndrome
0.273 0.727 0.000
N04 Nephrotic syndrome
0.273 0.727 0.000
N01 Rapidly progressive nephritic syndrome
0.273 0.727 0.000
N00 Acute nephritic syndrome
0.273 0.727 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.273 0.727 0.000
T83.0 Mechanical complication of urinary (indwelling) catheter
0.273 0.727 0.000
M48.9 Spondylopathy, unspecified
0.273 0.727 0.000
M48.8 Other specified spondylopathies
0.273 0.727 0.000
M48.5 Collapsed vertebra, not elsewhere classified
0.273 0.727 0.000
M48.4 Fatigue fracture of vertebra
0.273 0.727 0.000
M48.3 Traumatic spondylopathy
0.273 0.727 0.000
M48.2 Kissing spine
0.273 0.727 0.000
M48.1 Ankylosing hyperostosis [Forestier]
0.273 0.727 0.000
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified
0.273 0.727 0.000
S82.6 Fracture of lateral malleolus
0.273 0.727 0.000
W07 Fall involving chair
0.272 0.728 0.000
S32 Fracture of lumbar spine and pelvis
0.272 0.728 0.000
T31 Burns classified according to extent of body surface involved
0.272 0.728 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.272 0.728 0.000
M85 Other disorders of bone density and structure
0.272 0.728 0.000
M84 Disorders of continuity of bone
0.272 0.728 0.000
M83 Adult osteomalacia
0.272 0.728 0.000
M82 Osteoporosis in diseases classified elsewhere
0.272 0.728 0.000
S82.9 Fracture of lower leg, part unspecified
0.271 0.728 0.000
S82.7 Multiple fractures of lower leg
0.271 0.728 0.000
S82.4 Fracture of fibula alone
0.271 0.728 0.000
M54.16 Radiculopathy (Lumbar region)
0.271 0.729 0.000
O68.9 Labour and delivery complicated by foetal stress, unspecified
0.271 0.729 0.000
O68.3 Labour and delivery complicated by biochemical evidence of foetal stress
0.271 0.729 0.000
O63.2 Delayed delivery of second twin, triplet, etc.
0.271 0.729 0.000
S82.8 Fractures of other parts of lower leg
0.271 0.729 0.000
F03 Unspecified dementia
0.269 0.731 0.000
M99 Biomechanical lesions, not elsewhere classified
0.269 0.731 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.269 0.731 0.000
W19 Unspecified fall
0.269 0.731 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.269 0.731 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.269 0.731 0.000
Y35-Y36 Legal intervention and operations of war
0.269 0.731 0.000
Y10-Y34 Event of undetermined intent
0.269 0.731 0.000
Y00-Y09 Assault
0.269 0.731 0.000
X85-X99 Assault
0.269 0.731 0.000
X60-X84 Intentional self-harm
0.269 0.731 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.269 0.731 0.000
X50-X57 Overexertion, travel and privation
0.269 0.731 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.269 0.731 0.000
X30-X39 Exposure to forces of nature
0.269 0.731 0.000
X20-X29 Contact with venomous animals and plants
0.269 0.731 0.000
X10-X19 Contact with heat and hot substances
0.269 0.731 0.000
X00-X09 Exposure to smoke, fire and flames
0.269 0.731 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.269 0.731 0.000
W75-W84 Other accidental threats to breathing
0.269 0.731 0.000
W65-W74 Accidental drowning and submersion
0.269 0.731 0.000
W50-W64 Exposure to animate mechanical forces
0.269 0.731 0.000
V98-V99 Other and unspecified transport accidents
0.269 0.731 0.000
V95-V97 Air and space transport accidents
0.269 0.731 0.000
V90-V94 Water transport accidents
0.269 0.731 0.000
V80-V89 Other land transport accidents
0.269 0.731 0.000
V70-V79 Bus occupant injured in transport accident
0.269 0.731 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.269 0.731 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.269 0.731 0.000
V40-V49 Car occupant injured in transport accident
0.269 0.731 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.269 0.731 0.000
V20-V29 Motorcycle rider injured in transport accident
0.269 0.731 0.000
V01-V09 Pedestrian injured in transport accident
0.269 0.731 0.000
O68.0 Labour and delivery complicated by foetal heart rate anomaly
0.269 0.731 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.268 0.731 0.000
M54.96 Dorsalgia, unspecified (Lumbar region)
0.268 0.732 0.000
T51.0 Ethanol
0.268 0.732 0.000
S27 Injury of other and unspecified intrathoracic organs
0.268 0.732 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.267 0.733 0.000
T75 Effects of other external causes
0.266 0.734 0.000
T74 Maltreatment syndromes
0.266 0.734 0.000
T73 Effects of other deprivation
0.266 0.734 0.000
T70 Effects of air pressure and water pressure
0.266 0.734 0.000
T69 Other effects of reduced temperature
0.266 0.734 0.000
T67 Effects of heat and light
0.266 0.734 0.000
T71 Asphyxiation
0.266 0.734 0.000
T68 Hypothermia
0.266 0.734 0.000
T66 Unspecified effects of radiation
0.266 0.734 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.266 0.734 0.000
O72 Postpartum haemorrhage
0.265 0.735 0.000
D70 Agranulocytosis
0.265 0.735 0.000
S00 Superficial injury of head
0.265 0.735 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.264 0.736 0.000
D67 Hereditary factor IX deficiency
0.264 0.736 0.000
D66 Hereditary factor VIII deficiency
0.264 0.736 0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.264 0.736 0.000
S29 Other and unspecified injuries of thorax
0.263 0.736 0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax
0.263 0.736 0.000
S26 Injury of heart
0.263 0.736 0.000
S25 Injury of blood vessels of thorax
0.263 0.736 0.000
S24 Injury of nerves and spinal cord at thorax level
0.263 0.736 0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax
0.263 0.736 0.000
S21 Open wound of thorax
0.263 0.736 0.000
S20 Superficial injury of thorax
0.263 0.736 0.000
O04 Medical abortion
0.263 0.737 0.000
F10.2 Dependence syndrome
0.263 0.737 0.000
D73 Diseases of spleen
0.263 0.737 0.000
O69.2 Labour and delivery complicated by other cord entanglement
0.263 0.737 0.000
A41.5 Septicaemia due to other Gram-negative organisms
0.262 0.738 0.000
M25.89 Other specified joint disorders (Site unspecified)
0.261 0.739 0.000
M25.88 Other specified joint disorders (Other)
0.261 0.739 0.000
M25.87 Other specified joint disorders (Ankle and foot)
0.261 0.739 0.000
M25.86 Other specified joint disorders (Lower leg)
0.261 0.739 0.000
M25.85 Other specified joint disorders (Pelvic region and thigh)
0.261 0.739 0.000
M25.83 Other specified joint disorders (Forearm)
0.261 0.739 0.000
M25.82 Other specified joint disorders (Upper arm)
0.261 0.739 0.000
M25.81 Other specified joint disorders (Shoulder region)
0.261 0.739 0.000
M25.80 Other specified joint disorders (Multiple sites)
0.261 0.739 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.261 0.739 0.000
S48 Traumatic amputation of shoulder and upper arm
0.261 0.739 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.261 0.739 0.000
S45 Injury of blood vessels at shoulder and upper arm level
0.261 0.739 0.000
S44 Injury of nerves at shoulder and upper arm level
0.261 0.739 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.261 0.739 0.000
S41 Open wound of shoulder and upper arm
0.261 0.739 0.000
S40 Superficial injury of shoulder and upper arm
0.261 0.739 0.000
S47 Crushing injury of shoulder and upper arm
0.261 0.739 0.000
V10-V19 Pedal cyclist injured in transport accident
0.261 0.739 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.260 0.740 0.000
S02 Fracture of skull and facial bones
0.260 0.740 0.000
O42 Premature rupture of membranes
0.260 0.740 0.000
M90 Osteopathies in diseases classified elsewhere
0.259 0.740 0.000
M88 Paget's disease of bone [osteitis deformans]
0.259 0.740 0.000
M87 Osteonecrosis
0.259 0.740 0.000
M86 Osteomyelitis
0.259 0.740 0.000
B35-B49 Mycoses
0.259 0.740 0.000
S06 Intracranial injury
0.259 0.740 0.000
N13 Obstructive and reflux uropathy
0.259 0.741 0.000
S52.5 Fracture of lower end of radius
0.259 0.741 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.259 0.741 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.259 0.741 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.259 0.741 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.259 0.741 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.259 0.741 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.259 0.741 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.259 0.741 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.259 0.741 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.259 0.741 0.000
T36 Poisoning by systemic antibiotics
0.259 0.741 0.000
T83.9 Unspecified complication of genito-urinary prosthetic device, implant and graft
0.259 0.741 0.000
T83.6 Infection and inflammatory reaction due to prosthetic device, implant and graft in genital tract
0.259 0.741 0.000
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system
0.259 0.741 0.000
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract
0.259 0.741 0.000
T83.3 Mechanical complication of intra-uterine contraceptive device
0.259 0.741 0.000
T83.2 Mechanical complication of graft of urinary organ
0.259 0.741 0.000
T83.1 Mechanical complication of other urinary devices and implants
0.259 0.741 0.000
Z48 Other surgical follow-up care
0.259 0.741 0.000
S92 Fracture of foot, except ankle
0.258 0.742 0.000
M53.9 Dorsopathy, unspecified
0.258 0.742 0.000
M53.8 Other specified dorsopathies
0.258 0.742 0.000
M53.2 Spinal instabilities
0.258 0.742 0.000
M53.1 Cervicobrachial syndrome
0.258 0.742 0.000
M53.0 Cervicocranial syndrome
0.258 0.742 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.258 0.742 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.257 0.742 0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis
0.257 0.742 0.000
S37 Injury of urinary and pelvic organs
0.257 0.742 0.000
S36 Injury of intra-abdominal organs
0.257 0.742 0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level
0.257 0.742 0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level
0.257 0.742 0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis
0.257 0.742 0.000
S31 Open wound of abdomen, lower back and pelvis
0.257 0.742 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.257 0.742 0.000
T32 Corrosions classified according to extent of body surface involved
0.257 0.742 0.000
T30 Burn and corrosion, body region unspecified
0.257 0.742 0.000
T29 Burns and corrosions of multiple body regions
0.257 0.742 0.000
F10.3 Withdrawal state
0.257 0.743 0.000
M11 Other crystal arthropathies
0.256 0.743 0.000
S70.9 Superficial injury of hip and thigh, unspecified
0.256 0.744 0.000
O70.0 First degree perineal laceration during delivery
0.256 0.744 0.000
M48.09 Spinal stenosis (Site unspecified)
0.255 0.745 0.000
M48.08 Spinal stenosis (Sacral and sacrococcygeal region)
0.255 0.745 0.000
M48.05 Spinal stenosis (Thoracolumbar region)
0.255 0.745 0.000
M48.04 Spinal stenosis (Thoracic region)
0.255 0.745 0.000
M48.03 Spinal stenosis (Cervicothoracic region)
0.255 0.745 0.000
M48.01 Spinal stenosis (Occipito-atlanto-axial region)
0.255 0.745 0.000
M48.00 Spinal stenosis (Multiple sites in spine)
0.255 0.745 0.000
S82.00 Fracture of patella (closed)
0.255 0.745 0.000
A00-A09 Intestinal infectious diseases
0.255 0.745 0.000
S08 Traumatic amputation of part of head
0.255 0.745 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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