TreeWAS – Variant ID: rs113161398

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
# Top node	1.000	0.000
Chapter XI Diseases of the digestive system	1.000	0.000
Chapter VII Diseases of the eye and adnexa	0.999	0.001
H30-H36 Disorders of choroid and retina	0.997	0.003
Chapter II Neoplasms	0.996	0.004
D10-D36 Benign neoplasms	0.993	0.007
Chapter X Diseases of the respiratory system	0.992	0.008
H35 Other retinal disorders	0.992	0.008
Chapter VIII Diseases of the ear and mastoid process	0.991	0.009
K20-K31 Diseases of oesophagus, stomach and duodenum	0.990	0.010
D12 Benign neoplasm of colon, rectum, anus and anal canal	0.986	0.014
Chapter XIV Diseases of the genitourinary system	0.986	0.014
H35.3 Degeneration of macula and posterior pole	0.974	0.026
N17-N19 Renal failure	0.971	0.029
K80-K87 Disorders of gallbladder, biliary tract and pancreas	0.968	0.032
Chapter XXI Factors influencing health status and contact with health services	0.963	0.037
Chapter I Certain infectious and parasitic diseases	0.960	0.040
Z20-Z29 Persons with potential health hazards related to communicable diseases	0.960	0.040
J20-J22 Other acute lower respiratory infections	0.959	0.041
K25 Gastric ulcer	0.957	0.043
Z22 Carrier of infectious disease	0.957	0.043
Z22.3 Carrier of other specified bacterial diseases	0.955	0.045
D12.8 Rectum	0.953	0.047
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.953	0.047
N40-N51 Diseases of male genital organs	0.943	0.057
K65-K67 Diseases of peritoneum	0.940	0.060
K35-K38 Diseases of appendix	0.938	0.062
H65-H75 Diseases of middle ear and mastoid	0.937	0.063
K80 Cholelithiasis	0.937	0.063
N18 Chronic renal failure	0.936	0.064
D12.2 Ascending colon	0.934	0.066
M70-M79 Other soft tissue disorders	0.933	0.067
K90-K93 Other diseases of the digestive system	0.931	0.069
H80-H83 Diseases of inner ear	0.930	0.070
D12.7 Rectosigmoid junction	0.929	0.071
D11 Benign neoplasm of major salivary glands	0.927	0.073
K70-K77 Diseases of liver	0.925	0.075
N41 Inflammatory diseases of prostate	0.924	0.076
K20 Oesophagitis	0.920	0.080
J22 Unspecified acute lower respiratory infection	0.919	0.081
N00-N08 Glomerular diseases	0.919	0.081
J30-J39 Other diseases of upper respiratory tract	0.918	0.082
H35.8 Other specified retinal disorders	0.915	0.085
H25-H28 Disorders of lens	0.910	0.090
Chapter IV Endocrine, nutritional and metabolic diseases	0.910	0.090
M79 Other soft tissue disorders, not elsewhere classified	0.908	0.092
D32 Benign neoplasm of meninges	0.907	0.093
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.907	0.093
Chapter XX External causes of morbidity and mortality	0.904	0.096
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	0.902	0.098
K80.2 Calculus of gallbladder without cholecystitis	0.902	0.098
N19 Unspecified renal failure	0.898	0.102
Chapter XXII Codes for special purposes	0.898	0.102
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.896	0.104
K25.9 Unspecified as acute or chronic, without haemorrhage or perforation	0.896	0.104
K29 Gastritis and duodenitis	0.896	0.104
K66 Other disorders of peritoneum	0.890	0.110
K92 Other diseases of digestive system	0.887	0.113
H65 Nonsuppurative otitis media	0.886	0.114
H25 Senile cataract	0.885	0.115
N18.3 Chronic kidney disease, stage 3	0.885	0.115
J40-J47 Chronic lower respiratory diseases	0.884	0.116
K00-K14 Diseases of oral cavity, salivary glands and jaws	0.883	0.117
A00-A09 Intestinal infectious diseases	0.880	0.120
D11.0 Parotid gland	0.880	0.120
M79.6 Pain in limb	0.873	0.127
H83 Other diseases of inner ear	0.872	0.128
J33 Nasal polyp	0.869	0.131
K26 Duodenal ulcer	0.868	0.132
D18 Haemangioma and lymphangioma, any site	0.863	0.137
M05-M14 Inflammatory polyarthropathies	0.863	0.137
Z00-Z13 Persons encountering health services for examination and investigation	0.862	0.138
N41.9 Inflammatory disease of prostate, unspecified	0.862	0.138
K35 Acute appendicitis	0.861	0.138
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.861	0.139
K29.7 Gastritis, unspecified	0.851	0.149
C15-C26 Malignant neoplasms of digestive organs	0.850	0.150
K92.2 Gastro-intestinal haemorrhage, unspecified	0.850	0.150
M79.66 Pain in limb (Lower leg)	0.849	0.151
N47 Redundant prepuce, phimosis and paraphimosis	0.849	0.151
J44 Other chronic obstructive pulmonary disease	0.847	0.153
R00-R09 Symptoms and signs involving the circulatory and respiratory systems	0.847	0.153
Z09 Follow-up examination after treatment for conditions other than malignant neoplasms	0.845	0.155
D32.0 Cerebral meninges	0.845	0.155
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.843	0.157
E70-E90 Metabolic disorders	0.842	0.158
K25.4 Chronic or unspecified with haemorrhage	0.842	0.158
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.842	0.158
K66.0 Peritoneal adhesions	0.834	0.166
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.833	0.167
H83.0 Labyrinthitis	0.830	0.170
H25.9 Senile cataract, unspecified	0.828	0.172
H36 Retinal disorders in diseases classified elsewhere	0.827	0.173
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.825	0.175
N41.0 Acute prostatitis	0.825	0.175
H25.0 Senile incipient cataract	0.824	0.176
K08 Other disorders of teeth and supporting structures	0.819	0.181
H34 Retinal vascular occlusions	0.816	0.184
H65.3 Chronic mucoid otitis media	0.816	0.184
K81 Cholecystitis	0.814	0.186
M79.8 Other specified soft tissue disorders	0.811	0.189
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.810	0.190
D21 Other benign neoplasms of connective and other soft tissue	0.809	0.191
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.808	0.192
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.808	0.192
A04 Other bacterial intestinal infections	0.806	0.194
B95-B98 Bacterial, viral and other infectious agents	0.803	0.197
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour	0.802	0.198
N25-N29 Other disorders of kidney and ureter	0.801	0.199
K80.1 Calculus of gallbladder with other cholecystitis	0.798	0.202
C51-C58 Malignant neoplasms of female genital organs	0.798	0.202
K31 Other diseases of stomach and duodenum	0.798	0.202
H60-H62 Diseases of external ear	0.797	0.203
Z09.0 Follow-up examination after surgery for other conditions	0.797	0.203
C79 Secondary malignant neoplasm of other sites	0.797	0.203
N03 Chronic nephritic syndrome	0.796	0.203
H35.9 Retinal disorder, unspecified	0.793	0.206
R30-R39 Symptoms and signs involving the urinary system	0.793	0.207
B90-B94 Sequelae of infectious and parasitic diseases	0.793	0.207
H55-H59 Other disorders of eye and adnexa	0.792	0.208
R47-R49 Symptoms and signs involving speech and voice	0.792	0.208
H40-H42 Glaucoma	0.791	0.209
J20 Acute bronchitis	0.791	0.209
H66 Suppurative and unspecified otitis media	0.790	0.210
Z21 Asymptomatic human immunodeficiency virus [HIV] infection status	0.790	0.210
D16 Benign neoplasm of bone and articular cartilage	0.787	0.213
A30-A49 Other bacterial diseases	0.785	0.214
K37 Unspecified appendicitis	0.785	0.215
N02 Recurrent and persistent haematuria	0.782	0.218
J44.9 Chronic obstructive pulmonary disease, unspecified	0.782	0.218
M75 Shoulder lesions	0.782	0.218
E10-E14 Diabetes mellitus	0.781	0.219
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.780	0.220
H90-H95 Other disorders of ear	0.777	0.223
J90-J94 Other diseases of pleura	0.775	0.225
D34 Benign neoplasm of thyroid gland	0.775	0.225
N18.4 Chronic kidney disease, stage 4	0.774	0.225
D12.5 Sigmoid colon	0.774	0.226
D37-D48 Neoplasms of uncertain or unknown behaviour	0.772	0.228
A80-A89 Viral infections of the central nervous system	0.771	0.229
K74 Fibrosis and cirrhosis of liver	0.770	0.230
D18.0 Haemangioma, any site	0.770	0.230
J32 Chronic sinusitis	0.768	0.232
N41.1 Chronic prostatitis	0.766	0.234
K35.9 Acute appendicitis, unspecified	0.765	0.235
C78 Secondary malignant neoplasm of respiratory and digestive organs	0.764	0.236
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection	0.763	0.237
Chapter V Mental and behavioural disorders	0.763	0.237
J33.0 Polyp of nasal cavity	0.763	0.237
E20-E35 Disorders of other endocrine glands	0.761	0.239
R06 Abnormalities of breathing	0.759	0.241
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems	0.758	0.242
D22 Melanocytic naevi	0.756	0.244
N50 Other disorders of male genital organs	0.755	0.244
J38 Diseases of vocal cords and larynx, not elsewhere classified	0.755	0.245
K70 Alcoholic liver disease	0.755	0.245
H65.9 Nonsuppurative otitis media, unspecified	0.754	0.246
D35 Benign neoplasm of other and unspecified endocrine glands	0.751	0.249
K85 Acute pancreatitis	0.750	0.250
R42 Dizziness and giddiness	0.749	0.251
R00 Abnormalities of heart beat	0.745	0.255
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.744	0.256
H53-H54 Visual disturbances and blindness	0.743	0.257
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.743	0.257
R39 Other symptoms and signs involving the urinary system	0.741	0.259
M79.60 Pain in limb (Multiple sites)	0.741	0.259
J95-J99 Other diseases of the respiratory system	0.741	0.259
K29.8 Duodenitis	0.741	0.259
Z09.8 Follow-up examination after other treatment for other conditions	0.741	0.259
A04.8 Other specified bacterial intestinal infections	0.740	0.260
K86 Other diseases of pancreas	0.739	0.261
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.736	0.264
M79.86 Other specified soft tissue disorders (Lower leg)	0.735	0.265
N18.0 End-stage renal disease	0.735	0.265
D69 Purpura and other haemorrhagic conditions	0.734	0.266
N20-N23 Urolithiasis	0.734	0.266
M91-M94 Chondropathies	0.734	0.266
J33.9 Nasal polyp, unspecified	0.734	0.266
K27 Peptic ulcer, site unspecified	0.733	0.267
K92.0 Haematemesis	0.732	0.268
K80.0 Calculus of gallbladder with acute cholecystitis	0.732	0.268
K66.8 Other specified disorders of peritoneum	0.731	0.269
H81 Disorders of vestibular function	0.731	0.269
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.730	0.269
K72 Hepatic failure, not elsewhere classified	0.730	0.270
K81.9 Cholecystitis, unspecified	0.730	0.270
K29.1 Other acute gastritis	0.730	0.270
K25.3 Acute without haemorrhage or perforation	0.728	0.272
D50-D53 Nutritional anaemias	0.728	0.272
U80 Agent resistant to penicillin and related antibiotics	0.727	0.273
D14 Benign neoplasm of middle ear and respiratory system	0.727	0.273
K26.7 Chronic without haemorrhage or perforation	0.725	0.275
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.725	0.275
H33 Retinal detachments and breaks	0.724	0.276
C79.3 Secondary malignant neoplasm of brain and cerebral meninges	0.721	0.279
K31.9 Disease of stomach and duodenum, unspecified	0.721	0.279
M75.5 Bursitis of shoulder	0.721	0.279
J33.8 Other polyp of sinus	0.721	0.279
R06.0 Dyspnoea	0.720	0.280
H35.0 Background retinopathy and retinal vascular changes	0.719	0.281
M13 Other arthritis	0.718	0.282
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
Z04 Examination and observation for other reasons	0.717	0.283
H46-H48 Disorders of optic nerve and visual pathways	0.716	0.284
H10-H13 Disorders of conjunctiva	0.716	0.284
E87 Other disorders of fluid, electrolyte and acid-base balance	0.716	0.284
K08.3 Retained dental root	0.715	0.285
H32 Chorioretinal disorders in diseases classified elsewhere	0.715	0.285
H31 Other disorders of choroid	0.715	0.285
H30 Chorioretinal inflammation	0.715	0.285
H35.4 Peripheral retinal degeneration	0.714	0.286
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.714	0.286
C40-C41 Malignant neoplasms of bone and articular cartilage	0.714	0.286
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.714	0.286
E86 Volume depletion	0.713	0.287
Z09.9 Follow-up examination after unspecified treatment for other conditions	0.713	0.287
K91 Postprocedural disorders of digestive system, not elsewhere classified	0.713	0.287
K65 Peritonitis	0.712	0.288
D31 Benign neoplasm of eye and adnexa	0.712	0.288
D30 Benign neoplasm of urinary organs	0.712	0.288
D29 Benign neoplasm of male genital organs	0.712	0.288
D28 Benign neoplasm of other and unspecified female genital organs	0.712	0.288
D26 Other benign neoplasms of uterus	0.712	0.288
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum	0.712	0.288
D19 Benign neoplasm of mesothelial tissue	0.712	0.288
D15 Benign neoplasm of other and unspecified intrathoracic organs	0.712	0.288
D10 Benign neoplasm of mouth and pharynx	0.712	0.288
H35.7 Separation of retinal layers	0.711	0.289
H35.6 Retinal haemorrhage	0.711	0.289
H35.5 Hereditary retinal dystrophy	0.711	0.289
H35.2 Other proliferative retinopathy	0.711	0.289
H35.1 Retinopathy of prematurity	0.711	0.289
K28 Gastrojejunal ulcer	0.710	0.290
K23 Disorders of oesophagus in diseases classified elsewhere	0.710	0.290
K76 Other diseases of liver	0.709	0.291
M05 Seropositive rheumatoid arthritis	0.709	0.291
N03.9 Unspecified	0.709	0.291
M00-M03 Infectious arthropathies	0.708	0.292
R32 Unspecified urinary incontinence	0.707	0.293
D12.9 Anus and anal canal	0.707	0.293
D12.1 Appendix	0.707	0.293
N05 Unspecified nephritic syndrome	0.706	0.294
H36.0 Diabetic retinopathy	0.706	0.294
S40-S49 Injuries to the shoulder and upper arm	0.706	0.294
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis	0.705	0.295
J39 Other diseases of upper respiratory tract	0.704	0.296
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.703	0.297
A09 Diarrhoea and gastro-enteritis of presumed infectious origin	0.702	0.298
N18.9 Chronic renal failure, unspecified	0.700	0.300
C20 Malignant neoplasm of rectum	0.700	0.300
B96 Other bacterial agents as the cause of diseases classified to other chapters	0.700	0.300
M86-M90 Other osteopathies	0.700	0.300
H25.8 Other senile cataract	0.699	0.301
K75 Other inflammatory liver diseases	0.698	0.302
C18 Malignant neoplasm of colon	0.698	0.302
Z11 Special screening examination for infectious and parasitic diseases	0.698	0.302
R49 Voice disturbances	0.697	0.303
K11 Diseases of salivary glands	0.697	0.303
J40 Bronchitis, not specified as acute or chronic	0.697	0.303
Z63 Other problems related to primary support group, including family circumstances	0.696	0.304
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.696	0.304
K35.0 Acute appendicitis with generalised peritonitis	0.696	0.304
R39.1 Other difficulties with micturition	0.694	0.306
Y43 Primarily systemic agents	0.694	0.306
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere	0.694	0.306
A04.7 Enterocolitis due to Clostridium difficile	0.691	0.309
W20-W49 Exposure to inanimate mechanical forces	0.691	0.309
Q60-Q64 Congenital malformations of the urinary system	0.690	0.310
H72 Perforation of tympanic membrane	0.689	0.310
D80-D89 Certain disorders involving the immune mechanism	0.689	0.311
B99-B99 Other infectious diseases	0.688	0.311
B85-B89 Pediculosis, acariasis and other infestations	0.688	0.311
B65-B83 Helminthiases	0.688	0.311
B50-B64 Protozoal diseases	0.688	0.311
B20-B24 Human immunodeficiency virus [HIV] disease	0.688	0.311
B15-B19 Viral hepatitis	0.688	0.311
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.688	0.311
A75-A79 Rickettsioses	0.688	0.311
A70-A74 Other diseases caused by chlamydiae	0.688	0.311
A65-A69 Other spirochaetal diseases	0.688	0.311
A50-A64 Infections with a predominantly sexual mode of transmission	0.688	0.311
A20-A28 Certain zoonotic bacterial diseases	0.688	0.311
A15-A19 Tuberculosis	0.688	0.311
Z28 Immunisation not carried out	0.688	0.312
Z27 Need for immunisation against combinations of infectious diseases	0.688	0.312
Z26 Need for immunisation against other single infectious diseases	0.688	0.312
Z25 Need for immunisation against other single viral diseases	0.688	0.312
Z24 Need for immunisation against certain single viral diseases	0.688	0.312
Z23 Need for immunisation against single bacterial diseases	0.688	0.312
Z20 Contact with and exposure to communicable diseases	0.688	0.312
Y60-Y69 Misadventures to patients during surgical and medical care	0.688	0.312
T15-T19 Effects of foreign body entering through natural orifice	0.688	0.312
M79.64 Pain in limb (Hand)	0.688	0.312
K82 Other diseases of gallbladder	0.687	0.312
J21 Acute bronchiolitis	0.687	0.313
M80-M85 Disorders of bone density and structure	0.687	0.313
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.687	0.313
K25.6 Chronic or unspecified with both haemorrhage and perforation	0.686	0.314
K25.5 Chronic or unspecified with perforation	0.686	0.314
K25.2 Acute with both haemorrhage and perforation	0.686	0.314
K25.1 Acute with perforation	0.686	0.314
K25.0 Acute with haemorrhage	0.686	0.314
Z22.9 Carrier of infectious disease, unspecified	0.686	0.314
Z22.8 Carrier of other infectious diseases	0.686	0.314
Z22.6 Carrier of human T-lymphotropic virus type 1 [HTLV-1] infection	0.686	0.314
Z22.5 Carrier of viral hepatitis	0.686	0.314
Z22.4 Carrier of infections with a predominantly sexual mode of transmission	0.686	0.314
Z22.2 Carrier of diphtheria	0.686	0.314
Z22.1 Carrier of other intestinal infectious diseases	0.686	0.314
Z22.0 Carrier of typhoid	0.686	0.314
Z57 Occupational exposure to risk-factors	0.686	0.314
N99-N99 Other disorders of the genitourinary system	0.685	0.314
D36 Benign neoplasm of other and unspecified sites	0.685	0.315
H66.9 Otitis media, unspecified	0.684	0.316
D12.3 Transverse colon	0.684	0.316
N10-N16 Renal tubulo-interstitial diseases	0.683	0.317
M60-M63 Disorders of muscles	0.683	0.317
J00-J06 Acute upper respiratory infections	0.681	0.319
N04 Nephrotic syndrome	0.680	0.320
D17 Benign lipomatous neoplasm	0.680	0.320
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.680	0.320
E27 Other disorders of adrenal gland	0.680	0.320
N42 Other disorders of prostate	0.679	0.321
K08.9 Disorder of teeth and supporting structures, unspecified	0.677	0.323
K26.4 Chronic or unspecified with haemorrhage	0.677	0.323
M77 Other enthesopathies	0.677	0.323
N51 Disorders of male genital organs in diseases classified elsewhere	0.676	0.324
N49 Inflammatory disorders of male genital organs, not elsewhere classified	0.676	0.324
N46 Male infertility	0.676	0.324
N44 Torsion of testis	0.676	0.324
J43 Emphysema	0.676	0.324
E80 Disorders of porphyrin and bilirubin metabolism	0.676	0.324
D33 Benign neoplasm of brain and other parts of central nervous system	0.675	0.325
D68 Other coagulation defects	0.675	0.325
J60-J70 Lung diseases due to external agents	0.675	0.325
K26.9 Unspecified as acute or chronic, without haemorrhage or perforation	0.675	0.325
K12 Stomatitis and related lesions	0.675	0.325
H43-H45 Disorders of vitreous body and globe	0.675	0.325
R29 Other symptoms and signs involving the nervous and musculoskeletal systems	0.674	0.326
K67 Disorders of peritoneum in infectious diseases classified elsewhere	0.674	0.326
C48 Malignant neoplasm of retroperitoneum and peritoneum	0.674	0.326
C73 Malignant neoplasm of thyroid gland	0.673	0.327
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.673	0.327
B91 Sequelae of poliomyelitis	0.673	0.327
K38 Other diseases of appendix	0.673	0.327
K36 Other appendicitis	0.673	0.327
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.672	0.328
H74 Other disorders of middle ear and mastoid	0.672	0.328
H70 Mastoiditis and related conditions	0.672	0.328
H69 Other disorders of Eustachian tube	0.672	0.328
H68 Eustachian salpingitis and obstruction	0.672	0.328
H67 Otitis media in diseases classified elsewhere	0.672	0.328
K80.3 Calculus of bile duct with cholangitis	0.672	0.328
K80.8 Other cholelithiasis	0.672	0.328
K80.4 Calculus of bile duct with cholecystitis	0.672	0.328
N18.8 Other chronic renal failure	0.671	0.328
N18.2 Chronic kidney disease, stage 2	0.671	0.328
N18.1 Chronic kidney disease, stage 1	0.671	0.328
J20.9 Acute bronchitis, unspecified	0.671	0.329
C56 Malignant neoplasm of ovary	0.669	0.331
M76 Enthesopathies of lower limb, excluding foot	0.669	0.331
M73 Soft tissue disorders in diseases classified elsewhere	0.669	0.331
M71 Other bursopathies	0.669	0.331
M70 Soft tissue disorders related to use, overuse and pressure	0.669	0.331
N28 Other disorders of kidney and ureter, not elsewhere classified	0.668	0.332
M72 Fibroblastic disorders	0.668	0.332
N17 Acute renal failure	0.668	0.332
X40-X49 Accidental poisoning by and exposure to noxious substances	0.668	0.332
K93 Disorders of other digestive organs in diseases classified elsewhere	0.667	0.332
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.668	0.332
Q20-Q28 Congenital malformations of the circulatory system	0.667	0.333
N50.8 Other specified disorders of male genital organs	0.667	0.333
V10-V19 Pedal cyclist injured in transport accident	0.667	0.333
H80 Otosclerosis	0.667	0.333
H82 Vertiginous syndromes in diseases classified elsewhere	0.667	0.333
M10 Gout	0.667	0.333
N48 Other disorders of penis	0.666	0.334
K25.7 Chronic without haemorrhage or perforation	0.665	0.335
D11.9 Major salivary gland, unspecified	0.664	0.335
D11.7 Other major salivary glands	0.664	0.335
M40-M43 Deforming dorsopathies	0.664	0.336
E10 Insulin-dependent diabetes mellitus	0.664	0.336
D69.6 Thrombocytopenia, unspecified	0.664	0.336
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.664	0.336
K77 Liver disorders in diseases classified elsewhere	0.663	0.337
K73 Chronic hepatitis, not elsewhere classified	0.663	0.337
K71 Toxic liver disease	0.663	0.337
S20-S29 Injuries to the thorax	0.663	0.337
K74.6 Other and unspecified cirrhosis of liver	0.662	0.337
C78.0 Secondary malignant neoplasm of lung	0.662	0.338
N41.8 Other inflammatory diseases of prostate	0.662	0.338
N41.3 Prostatocystitis	0.662	0.338
N41.2 Abscess of prostate	0.662	0.338
C80 Malignant neoplasm without specification of site	0.661	0.339
R02 Gangrene, not elsewhere classified	0.661	0.339
Y52 Agents primarily affecting the cardiovascular system	0.661	0.339
M06 Other rheumatoid arthritis	0.660	0.340
J91 Pleural effusion in conditions classified elsewhere	0.660	0.340
M45-M49 Spondylopathies	0.659	0.341
A41 Other septicaemia	0.659	0.341
H34.8 Other retinal vascular occlusions	0.659	0.341
N08 Glomerular disorders in diseases classified elsewhere	0.659	0.341
N07 Hereditary nephropathy, not elsewhere classified	0.659	0.341
N06 Isolated proteinuria with specified morphological lesion	0.659	0.341
N01 Rapidly progressive nephritic syndrome	0.659	0.341
N00 Acute nephritic syndrome	0.659	0.341
J37 Chronic laryngitis and laryngotracheitis	0.658	0.342
N02.8 Other	0.658	0.342
H61 Other disorders of external ear	0.658	0.342
K35.8 Acute appendicitis, other and unspecified	0.657	0.343
K92.9 Disease of digestive system, unspecified	0.655	0.345
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis	0.655	0.345
T66-T78 Other and unspecified effects of external causes	0.655	0.345
K10 Other diseases of jaws	0.655	0.345
R00.0 Tachycardia, unspecified	0.655	0.345
M79.62 Pain in limb (Upper arm)	0.654	0.345
J46 Status asthmaticus	0.654	0.346
C16 Malignant neoplasm of stomach	0.654	0.346
M75.0 Adhesive capsulitis of shoulder	0.653	0.347
D12.6 Colon, unspecified	0.653	0.347
H28 Cataract and other disorders of lens in diseases classified elsewhere	0.653	0.347
H27 Other disorders of lens	0.653	0.347
K05 Gingivitis and periodontal diseases	0.653	0.347
E40-E46 Malnutrition	0.652	0.347
Q00-Q07 Congenital malformations of the nervous system	0.652	0.348
K14 Diseases of tongue	0.651	0.349
M79.9 Soft tissue disorder, unspecified	0.651	0.349
M79.7 Fibromyalgia	0.651	0.349
M79.5 Residual foreign body in soft tissue	0.651	0.349
M79.4 Hypertrophy of (infrapatellar) fat pad	0.651	0.349
M79.3 Panniculitis, unspecified	0.651	0.349
M79.2 Neuralgia and neuritis, unspecified	0.651	0.349
M79.1 Myalgia	0.651	0.349
Y51 Drugs primarily affecting the autonomic nervous system	0.651	0.349
K08.8 Other specified disorders of teeth and supporting structures	0.650	0.350
D32.9 Meninges, unspecified	0.650	0.350
D32.1 Spinal meninges	0.650	0.350
D55-D59 Haemolytic anaemias	0.650	0.350
D24 Benign neoplasm of breast	0.649	0.351
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.648	0.351
Y35-Y36 Legal intervention and operations of war	0.648	0.351
Y10-Y34 Event of undetermined intent	0.648	0.351
Y00-Y09 Assault	0.648	0.351
X85-X99 Assault	0.648	0.351
X58-X59 Accidental exposure to other and unspecified factors	0.648	0.351
X50-X57 Overexertion, travel and privation	0.648	0.351
X30-X39 Exposure to forces of nature	0.648	0.351
X20-X29 Contact with venomous animals and plants	0.648	0.351
X10-X19 Contact with heat and hot substances	0.648	0.351
X00-X09 Exposure to smoke, fire and flames	0.648	0.351
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.648	0.351
W75-W84 Other accidental threats to breathing	0.648	0.351
W65-W74 Accidental drowning and submersion	0.648	0.351
W50-W64 Exposure to animate mechanical forces	0.648	0.351
V98-V99 Other and unspecified transport accidents	0.648	0.351
V95-V97 Air and space transport accidents	0.648	0.351
V90-V94 Water transport accidents	0.648	0.351
V80-V89 Other land transport accidents	0.648	0.351
V70-V79 Bus occupant injured in transport accident	0.648	0.351
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.648	0.351
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.648	0.351
V40-V49 Car occupant injured in transport accident	0.648	0.351
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.648	0.351
V20-V29 Motorcycle rider injured in transport accident	0.648	0.351
V01-V09 Pedestrian injured in transport accident	0.648	0.351
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.648	0.352
D21.2 Connective and other soft tissue of lower limb, including hip	0.647	0.353
R95-R99 Ill-defined and unknown causes of mortality	0.647	0.353
J30 Vasomotor and allergic rhinitis	0.646	0.353
J09-J18 Influenza and pneumonia	0.645	0.355
C76 Malignant neoplasm of other and ill-defined sites	0.643	0.357
K29.9 Gastroduodenitis, unspecified	0.642	0.357
K29.3 Chronic superficial gastritis	0.642	0.357
K29.2 Alcoholic gastritis	0.642	0.357
H40 Glaucoma	0.642	0.358
Z29 Need for other prophylactic measures	0.642	0.358
S10-S19 Injuries to the neck	0.640	0.360
D16.4 Bones of skull and face	0.640	0.360
N60-N64 Disorders of breast	0.640	0.360
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.639	0.361
Q50-Q56 Congenital malformations of genital organs	0.639	0.361
Z12 Special screening examination for neoplasms	0.639	0.361
K66.9 Disorder of peritoneum, unspecified	0.638	0.362
K66.1 Haemoperitoneum	0.638	0.362
C78.5 Secondary malignant neoplasm of large intestine and rectum	0.638	0.362
K07 Dentofacial anomalies [including malocclusion]	0.636	0.364
K92.8 Other specified diseases of digestive system	0.636	0.364
A87 Viral meningitis	0.636	0.364
U51 Admission status on psychiatric patients	0.636	0.364
H65.4 Other chronic nonsuppurative otitis media	0.635	0.365
H65.2 Chronic serous otitis media	0.635	0.365
H65.1 Other acute nonsuppurative otitis media	0.635	0.365
H65.0 Acute serous otitis media	0.635	0.365
H25.2 Senile cataract, morgagnian type	0.635	0.365
E87.0 Hyperosmolality and hypernatraemia	0.635	0.365
C15 Malignant neoplasm of oesophagus	0.635	0.365
E78.5 Hyperlipidaemia, unspecified	0.635	0.365
Q38-Q45 Other congenital malformations of the digestive system	0.634	0.365
J41 Simple and mucopurulent chronic bronchitis	0.633	0.366
K09 Cysts of oral region, not elsewhere classified	0.633	0.367

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations