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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs113529884
log Bayes Factor = 245.207
Chromosome 6   position 32,553,828  (GRCh37) Explore rs113529884 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
E05.9 Thyrotoxicosis, unspecified
1.000 0.000 0.000
E05.0 Thyrotoxicosis with diffuse goitre
1.000 0.000 0.000
K90.0 Coeliac disease
1.000 0.000 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
E05 Thyrotoxicosis [hyperthyroidism]
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
1.000 0.000 0.000
M06 Other rheumatoid arthritis
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
1.000 0.000 0.000
D80-D89 Certain disorders involving the immune mechanism
1.000 0.000 0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
E03 Other hypothyroidism
1.000 0.000 0.000
D86 Sarcoidosis
1.000 0.000 0.000
N00-N08 Glomerular diseases
1.000 0.000 0.000
E20-E35 Disorders of other endocrine glands
1.000 0.000 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.000 1.000
M06.3 Rheumatoid nodule
0.000 0.000 1.000
E03.9 Hypothyroidism, unspecified
0.999 0.001 0.000
# Top node
0.999 0.001 0.000
E10.9 Without complications
0.999 0.001 0.000
M05 Seropositive rheumatoid arthritis
0.000 0.001 0.999
M05-M14 Inflammatory polyarthropathies
0.001 0.002 0.998
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.998 0.002 0.000
Q60-Q64 Congenital malformations of the urinary system
0.998 0.002 0.000
N05 Unspecified nephritic syndrome
0.998 0.002 0.000
N04 Nephrotic syndrome
0.998 0.002 0.000
E83.1 Disorders of iron metabolism
0.000 0.003 0.997
Chapter XIV Diseases of the genitourinary system
0.997 0.003 0.000
N17-N19 Renal failure
0.997 0.003 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.996 0.004 0.000
N18 Chronic renal failure
0.996 0.004 0.000
Q61 Cystic kidney disease
0.995 0.005 0.000
M06.0 Seronegative rheumatoid arthritis
0.000 0.006 0.994
M06.34 Rheumatoid nodule (Hand)
0.000 0.007 0.993
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.008 0.992
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.000 0.008 0.992
E10.3 With ophthalmic complications
0.992 0.008 0.000
E27 Other disorders of adrenal gland
0.989 0.011 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.011 0.989
N18.3 Chronic kidney disease, stage 3
0.989 0.011 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.012 0.988
N04.9 Unspecified
0.987 0.013 0.000
D86.0 Sarcoidosis of lung
0.986 0.014 0.000
D86.9 Sarcoidosis, unspecified
0.986 0.014 0.000
D69 Purpura and other haemorrhagic conditions
0.984 0.016 0.000
Q61.3 Polycystic kidney, unspecified
0.981 0.019 0.000
E27.1 Primary adrenocortical insufficiency
0.981 0.019 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.020 0.980
E10.1 With ketoacidosis
0.980 0.020 0.000
K90 Intestinal malabsorption
0.978 0.022 0.000
M15-M19 Arthrosis
0.975 0.025 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.974 0.026 0.000
M18 Arthrosis of first carpometacarpal joint
0.973 0.027 0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.028 0.972
K90.9 Intestinal malabsorption, unspecified
0.972 0.028 0.000
Q60 Renal agenesis and other reduction defects of kidney
0.971 0.029 0.000
M18.0 Primary arthrosis of first carpometacarpal joints, bilateral
0.968 0.032 0.000
N05.2 Diffuse membranous glomerulonephritis
0.967 0.033 0.000
M17.1 Other primary gonarthrosis
0.966 0.034 0.000
M17 Gonarthrosis [arthrosis of knee]
0.965 0.035 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.959 0.041 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.000 0.044 0.956
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.954 0.046 0.000
E28 Ovarian dysfunction
0.953 0.047 0.000
D68 Other coagulation defects
0.949 0.051 0.000
N05.9 Unspecified
0.946 0.054 0.000
D69.4 Other primary thrombocytopenia
0.940 0.060 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.940 0.060 0.000
N17 Acute renal failure
0.937 0.063 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.933 0.067 0.000
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.071 0.929
E06 Thyroiditis
0.922 0.078 0.000
Q61.2 Polycystic kidney, adult type
0.922 0.078 0.000
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.081 0.919
M20-M25 Other joint disorders
0.916 0.084 0.000
D69.6 Thrombocytopenia, unspecified
0.915 0.085 0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.085 0.915
N18.2 Chronic kidney disease, stage 2
0.914 0.086 0.000
N04.2 Diffuse membranous glomerulonephritis
0.914 0.086 0.000
Q60.0 Renal agenesis, unilateral
0.905 0.095 0.000
M23 Internal derangement of knee
0.901 0.099 0.000
N05.1 Focal and segmental glomerular lesions
0.900 0.100 0.000
M23.3 Other meniscus derangements
0.899 0.101 0.000
D60-D64 Aplastic and other anaemias
0.898 0.102 0.000
D68.8 Other specified coagulation defects
0.898 0.102 0.000
E24 Cushing's syndrome
0.897 0.103 0.000
N08.3 Glomerular disorders in diabetes mellitus
0.897 0.103 0.000
N17.9 Acute renal failure, unspecified
0.894 0.106 0.000
E21.3 Hyperparathyroidism, unspecified
0.891 0.109 0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.109 0.891
E27.9 Disorder of adrenal gland, unspecified
0.890 0.110 0.000
Q60.2 Renal agenesis, unspecified
0.889 0.111 0.000
E28.2 Polycystic ovarian syndrome
0.889 0.111 0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver
0.887 0.113 0.000
E14 Unspecified diabetes mellitus
0.882 0.118 0.000
M35 Other systemic involvement of connective tissue
0.882 0.118 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.122 0.878
C82.0 Small cleaved cell, follicular
0.000 0.123 0.877
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)
0.873 0.127 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.870 0.130 0.000
M35.0 Sicca syndrome [Sjogren]
0.869 0.131 0.000
N04.1 Focal and segmental glomerular lesions
0.868 0.132 0.000
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)
0.867 0.133 0.000
D86.3 Sarcoidosis of skin
0.867 0.133 0.000
D69.3 Idiopathic thrombocytopenic purpura
0.867 0.133 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.134 0.866
E03.8 Other specified hypothyroidism
0.866 0.134 0.000
E10.2 With renal complications
0.863 0.137 0.000
N18.4 Chronic kidney disease, stage 4
0.861 0.139 0.000
D68.5 Primary Thrombophilia
0.859 0.141 0.000
M60-M63 Disorders of muscles
0.857 0.143 0.000
D86.8 Sarcoidosis of other and combined sites
0.856 0.144 0.000
M18.1 Other primary arthrosis of first carpometacarpal joint
0.855 0.145 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.854 0.146 0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.152 0.848
M23.5 Chronic instability of knee
0.847 0.153 0.000
C82.7 Other types of follicular non-Hodgkin's lymphoma
0.000 0.154 0.846
Q00-Q07 Congenital malformations of the nervous system
0.846 0.154 0.000
N05.5 Diffuse mesangiocapillary glomerulonephritis
0.843 0.157 0.000
M15 Polyarthrosis
0.843 0.157 0.000
D89.2 Hypergammaglobulinaemia, unspecified
0.843 0.157 0.000
E07 Other disorders of thyroid
0.842 0.158 0.000
D55-D59 Haemolytic anaemias
0.840 0.160 0.000
Q38 Other congenital malformations of tongue, mouth and pharynx
0.830 0.170 0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.829 0.171 0.000
C82.3 Follicular lymphoma grade IIIa
0.000 0.175 0.825
Q63 Other congenital malformations of kidney
0.825 0.175 0.000
Chapter IX Diseases of the circulatory system
0.824 0.176 0.000
E10.0 With coma
0.823 0.177 0.000
I12 Hypertensive renal disease
0.822 0.178 0.000
I10-I15 Hypertensive diseases
0.821 0.179 0.000
D80 Immunodeficiency with predominantly antibody defects
0.821 0.179 0.000
Chapter VII Diseases of the eye and adnexa
0.818 0.182 0.000
D64 Other anaemias
0.817 0.183 0.000
D61 Other aplastic anaemias
0.817 0.183 0.000
M23.34 Other meniscus derangements (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.816 0.184 0.000
E28.3 Primary ovarian failure
0.815 0.185 0.000
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.000 0.187 0.813
I12.9 Hypertensive renal disease without renal failure
0.812 0.188 0.000
D89.9 Disorder involving the immune mechanism, unspecified
0.811 0.189 0.000
N18.5 Chronic kidney disease, stage 5
0.811 0.189 0.000
H06.2 Dysthyroid exophthalmos
0.810 0.190 0.000
Q61.0 Congenital single renal cyst
0.809 0.191 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.808 0.192 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.808 0.192 0.000
E24.2 Drug-induced Cushing's syndrome
0.808 0.192 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.808 0.192 0.000
E10.4 With neurological complications
0.807 0.193 0.000
M23.51 Chronic instability of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.802 0.198 0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.199 0.801
C82.2 Large cell, follicular
0.000 0.200 0.799
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.201 0.799
Q44.6 Cystic disease of liver
0.797 0.203 0.000
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.206 0.794
E06.5 Other chronic thyroiditis
0.791 0.209 0.000
I12.0 Hypertensive renal disease with renal failure
0.788 0.212 0.000
D89.0 Polyclonal hypergammaglobulinaemia
0.786 0.214 0.000
D68.0 Von Willebrand's disease
0.785 0.215 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.782 0.218 0.000
M35.7 Hypermobility syndrome
0.781 0.219 0.000
M86-M90 Other osteopathies
0.780 0.220 0.000
M24 Other specific joint derangements
0.778 0.222 0.000
E10.7 With multiple complications
0.778 0.222 0.000
E16 Other disorders of pancreatic internal secretion
0.777 0.223 0.000
D50-D53 Nutritional anaemias
0.773 0.227 0.000
M32 Systemic lupus erythematosus
0.771 0.229 0.000
E31 Polyglandular dysfunction
0.766 0.234 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.763 0.237 0.000
E06.3 Autoimmune thyroiditis
0.763 0.237 0.000
M14 Arthropathies in other diseases classified elsewhere
0.000 0.240 0.760
N03 Chronic nephritic syndrome
0.757 0.243 0.000
D61.9 Aplastic anaemia, unspecified
0.756 0.244 0.000
E14.3 With ophthalmic complications
0.756 0.244 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.754 0.246 0.000
D86.1 Sarcoidosis of lymph nodes
0.753 0.247 0.000
K90.8 Other intestinal malabsorption
0.752 0.248 0.000
I71 Aortic aneurysm and dissection
0.751 0.249 0.000
Q61.9 Cystic kidney disease, unspecified
0.748 0.252 0.000
D68.6 Other Thrombophilia
0.747 0.253 0.000
D64.9 Anaemia, unspecified
0.746 0.254 0.000
D68.1 Hereditary factor XI deficiency
0.746 0.254 0.000
H05 Disorders of orbit
0.746 0.254 0.000
H30-H36 Disorders of choroid and retina
0.745 0.255 0.000
M24.1 Other articular cartilage disorders
0.740 0.260 0.000
E14.8 With unspecified complications
0.739 0.261 0.000
I11 Hypertensive heart disease
0.737 0.263 0.000
D69.9 Haemorrhagic condition, unspecified
0.736 0.263 0.000
H00.1 Chalazion
0.000 0.266 0.734
Q63.2 Ectopic kidney
0.734 0.266 0.000
E06.9 Thyroiditis, unspecified
0.734 0.266 0.000
N05.8 Other
0.733 0.267 0.000
N18.0 End-stage renal disease
0.731 0.269 0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes
0.730 0.270 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.729 0.271 0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.729 0.271 0.000
Q43 Other congenital malformations of intestine
0.728 0.272 0.000
M18.3 Other posttraumatic arthrosis of first carpometacarpal joint
0.726 0.273 0.000
M60 Myositis
0.726 0.274 0.000
D58 Other hereditary haemolytic anaemias
0.725 0.275 0.000
M17.5 Other secondary gonarthrosis
0.725 0.275 0.000
D69.8 Other specified haemorrhagic conditions
0.724 0.276 0.000
D69.2 Other nonthrombocytopenic purpura
0.724 0.276 0.000
E40-E46 Malnutrition
0.724 0.276 0.000
H05.2 Exophthalmic conditions
0.723 0.277 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.722 0.278 0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.721 0.279 0.000
N18.9 Chronic renal failure, unspecified
0.720 0.280 0.000
C82.4 Follicular lymphoma grade IIIb
0.000 0.280 0.719
M15.2 Bouchard's nodes (with arthropathy)
0.717 0.283 0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.283 0.717
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.283 0.717
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.283 0.717
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.283 0.717
E05.5 Thyroid crisis or storm
0.717 0.283 0.000
E05.4 Thyrotoxicosis factitia
0.717 0.283 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.717 0.283 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.717 0.283 0.000
M06.8 Other specified rheumatoid arthritis
0.000 0.283 0.717
M06.2 Rheumatoid bursitis
0.000 0.283 0.717
M06.1 Adult-onset Still's disease
0.000 0.283 0.717
N05.3 Diffuse mesangial proliferative glomerulonephritis
0.717 0.283 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.717 0.283 0.000
E00 Congenital iodine-deficiency syndrome
0.717 0.283 0.000
D81 Combined immunodeficiencies
0.717 0.283 0.000
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
E03.5 Myxoedema coma
0.717 0.283 0.000
E03.4 Atrophy of thyroid (acquired)
0.717 0.283 0.000
E03.3 Postinfectious hypothyroidism
0.717 0.283 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.717 0.283 0.000
N07 Hereditary nephropathy, not elsewhere classified
0.717 0.283 0.000
N06 Isolated proteinuria with specified morphological lesion
0.717 0.283 0.000
N01 Rapidly progressive nephritic syndrome
0.717 0.283 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.717 0.283 0.000
E32 Diseases of thymus
0.717 0.283 0.000
E30 Disorders of puberty, not elsewhere classified
0.717 0.283 0.000
E25 Adrenogenital disorders
0.717 0.283 0.000
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.283 0.717
M06.38 Rheumatoid nodule (Other)
0.000 0.283 0.717
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.283 0.717
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.283 0.717
M06.33 Rheumatoid nodule (Forearm)
0.000 0.283 0.717
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.283 0.717
M05.8 Other seropositive rheumatoid arthritis
0.000 0.284 0.716
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.284 0.716
M05.1 Rheumatoid lung disease
0.000 0.284 0.716
M05.0 Felty's syndrome
0.000 0.284 0.716
M09 Juvenile arthritis in diseases classified elsewhere
0.001 0.284 0.715
M08 Juvenile arthritis
0.001 0.284 0.715
N05.6 Dense deposit disease
0.715 0.285 0.000
N05.4 Diffuse endocapillary proliferative glomerulonephritis
0.715 0.285 0.000
N05.0 Minor glomerular abnormality
0.715 0.285 0.000
N04.8 Other
0.715 0.285 0.000
N04.7 Diffuse crescentic glomerulonephritis
0.715 0.285 0.000
N04.6 Dense deposit disease
0.715 0.285 0.000
N04.5 Diffuse mesangiocapillary glomerulonephritis
0.715 0.285 0.000
N04.4 Diffuse endocapillary proliferative glomerulonephritis
0.715 0.285 0.000
N04.3 Diffuse mesangial proliferative glomerulonephritis
0.715 0.285 0.000
Q40 Other congenital malformations of upper alimentary tract
0.715 0.285 0.000
D83 Common variable immunodeficiency
0.714 0.286 0.000
Q61.8 Other cystic kidney diseases
0.713 0.287 0.000
Q61.1 Polycystic kidney, infantile type
0.713 0.287 0.000
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.287 0.713
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.287 0.713
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.287 0.713
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.287 0.713
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.287 0.713
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.287 0.713
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.287 0.713
M24.16 Other articular cartilage disorders (Lower leg)
0.713 0.287 0.000
M15.1 Heberden's nodes (with arthropathy)
0.711 0.289 0.000
M34 Systemic sclerosis
0.710 0.290 0.000
E27.5 Adrenomedullary hyperfunction
0.709 0.291 0.000
E27.0 Other adrenocortical overactivity
0.709 0.291 0.000
M17.0 Primary gonarthrosis, bilateral
0.709 0.291 0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.709 0.291 0.000
M21 Other acquired deformities of limbs
0.706 0.294 0.000
E20 Hypoparathyroidism
0.705 0.295 0.000
H50 Other strabismus
0.704 0.296 0.000
E24.0 Pituitary-dependent Cushing's disease
0.704 0.296 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.703 0.297 0.000
C82.1 Mixed small cleaved and large cell, follicular
0.000 0.297 0.703
E29 Testicular dysfunction
0.703 0.297 0.000
Q44.4 Choledochal cyst
0.703 0.297 0.000
E22 Hyperfunction of pituitary gland
0.702 0.298 0.000
Q61.5 Medullary cystic kidney
0.702 0.298 0.000
E07.8 Other specified disorders of thyroid
0.701 0.298 0.000
K90.3 Pancreatic steatorrhoea
0.701 0.299 0.000
K90.2 Blind loop syndrome, not elsewhere classified
0.701 0.299 0.000
K90.1 Tropical sprue
0.701 0.299 0.000
N00 Acute nephritic syndrome
0.701 0.299 0.000
M18.9 Arthrosis of first carpometacarpal joint, unspecified
0.700 0.300 0.000
M62 Other disorders of muscle
0.700 0.300 0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.301 0.699
M23.35 Other meniscus derangements (Posterior horn of lateral meniscus)
0.698 0.302 0.000
M05.2 Rheumatoid vasculitis
0.000 0.302 0.698
M18.5 Other secondary arthrosis of first carpometacarpal joint
0.698 0.302 0.000
M18.4 Other secondary arthrosis of first carpometacarpal joints, bilateral
0.698 0.302 0.000
M18.2 Posttraumatic arthrosis of first carpometacarpal joints, bilateral
0.698 0.302 0.000
E16.2 Hypoglycaemia, unspecified
0.698 0.302 0.000
E14.1 With ketoacidosis
0.696 0.304 0.000
Q60.6 Potter's syndrome
0.696 0.304 0.000
Q60.5 Renal hypoplasia, unspecified
0.696 0.304 0.000
Q60.4 Renal hypoplasia, bilateral
0.696 0.304 0.000
Q60.3 Renal hypoplasia, unilateral
0.696 0.304 0.000
Q60.1 Renal agenesis, bilateral
0.696 0.304 0.000
N25-N29 Other disorders of kidney and ureter
0.693 0.307 0.000
N17.0 Acute renal failure with tubular necrosis
0.693 0.307 0.000
N18.1 Chronic kidney disease, stage 1
0.691 0.309 0.000
Q38.7 Pharyngeal pouch
0.690 0.310 0.000
H35 Other retinal disorders
0.689 0.311 0.000
M35.2 Behcet's disease
0.689 0.311 0.000
N02 Recurrent and persistent haematuria
0.688 0.312 0.000
Q42 Congenital absence, atresia and stenosis of large intestine
0.687 0.312 0.000
Q41 Congenital absence, atresia and stenosis of small intestine
0.687 0.312 0.000
M06.4 Inflammatory polyarthropathy
0.000 0.314 0.686
C82.6 Cutaneous follicle centre lymphoma
0.000 0.314 0.685
C82.5 Diffuse follicle centre lymphoma
0.000 0.314 0.685
Q39 Congenital malformations of oesophagus
0.685 0.315 0.000
D89.3 Immune reconstitution syndrome
0.684 0.316 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.684 0.316 0.000
D50 Iron deficiency anaemia
0.684 0.316 0.000
E28.9 Ovarian dysfunction, unspecified
0.684 0.316 0.000
E28.8 Other ovarian dysfunction
0.684 0.316 0.000
E28.1 Androgen excess
0.684 0.316 0.000
E28.0 Oestrogen excess
0.684 0.316 0.000
D69.1 Qualitative platelet defects
0.683 0.317 0.000
D89.1 Cryoglobulinaemia
0.682 0.318 0.000
I71.0 Dissection of aorta [any part]
0.681 0.319 0.000
I74 Arterial embolism and thrombosis
0.681 0.319 0.000
E23 Hypofunction and other disorders of pituitary gland
0.681 0.319 0.000
N08.5 Glomerular disorders in systemic connective tissue disorders
0.680 0.320 0.000
E26 Hyperaldosteronism
0.679 0.321 0.000
E10.8 With unspecified complications
0.678 0.322 0.000
M23.52 Chronic instability of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.676 0.324 0.000
N04.0 Minor glomerular abnormality
0.674 0.325 0.000
I70 Atherosclerosis
0.675 0.325 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.674 0.326 0.000
N08.8 Glomerular disorders in other diseases classified elsewhere
0.674 0.326 0.000
N08.2 Glomerular disorders in blood diseases and disorders involving the immune mechanism
0.674 0.326 0.000
N08.1 Glomerular disorders in neoplastic diseases
0.674 0.326 0.000
N08.0 Glomerular disorders in infectious and parasitic diseases classified elsewhere
0.674 0.326 0.000
D82 Immunodeficiency associated with other major defects
0.674 0.326 0.000
M21.0 Valgus deformity, not elsewhere classified
0.674 0.326 0.000
M32.1 Systemic lupus erythematosus with organ or system involvement
0.673 0.327 0.000
N17.2 Acute renal failure with medullary necrosis
0.672 0.328 0.000
Q44.7 Other congenital malformations of liver
0.671 0.329 0.000
Q61.4 Renal dysplasia
0.671 0.329 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.670 0.330 0.000
M23.0 Cystic meniscus
0.669 0.331 0.000
E21.4 Other specified disorders of parathyroid gland
0.669 0.331 0.000
M91-M94 Chondropathies
0.669 0.331 0.000
Q35-Q37 Cleft lip and cleft palate
0.669 0.331 0.000
Q45 Other congenital malformations of digestive system
0.669 0.331 0.000
Q07 Other congenital malformations of nervous system
0.668 0.332 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.668 0.332 0.000
E06.1 Subacute thyroiditis
0.666 0.333 0.000
Q05 Spina bifida
0.666 0.334 0.000
N17.1 Acute renal failure with acute cortical necrosis
0.665 0.335 0.000
N08.4 Glomerular disorders in other endocrine, nutritional and metabolic diseases
0.664 0.336 0.000
M86 Osteomyelitis
0.663 0.337 0.000
H34 Retinal vascular occlusions
0.662 0.338 0.000
E06.4 Drug-induced thyroiditis
0.661 0.339 0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.661 0.339 0.000
E06.0 Acute thyroiditis
0.661 0.339 0.000
M17.2 Posttraumatic gonarthrosis, bilateral
0.661 0.339 0.000
N17.8 Other acute renal failure
0.661 0.339 0.000
H35.4 Peripheral retinal degeneration
0.661 0.339 0.000
E14.4 With neurological complications
0.660 0.340 0.000
M21.06 Valgus deformity, not elsewhere classified (Lower leg)
0.659 0.341 0.000
H50.5 Heterophoria
0.659 0.341 0.000
D68.4 Acquired coagulation factor deficiency
0.658 0.342 0.000
Q44.5 Other congenital malformations of bile ducts
0.657 0.343 0.000
M07 Psoriatic and enteropathic arthropathies
0.000 0.346 0.653
Q38.6 Other congenital malformations of mouth
0.652 0.348 0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]
0.652 0.348 0.000
M12 Other specific arthropathies
0.001 0.348 0.652
E34 Other endocrine disorders
0.652 0.348 0.000
I77 Other disorders of arteries and arterioles
0.652 0.348 0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter
0.651 0.349 0.000
I11.9 Hypertensive heart disease without (congestive) heart failure
0.651 0.349 0.000
E14.5 With peripheral circulatory complications
0.649 0.350 0.000
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.649 0.351 0.000
E07.9 Disorder of thyroid, unspecified
0.649 0.351 0.000
E14.2 Withrenal complications
0.648 0.352 0.000
N02.2 Diffuse membranous glomerulonephritis
0.647 0.353 0.000
M23.37 Other meniscus derangements-Capsular lig
0.645 0.355 0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.644 0.356 0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.643 0.357 0.000
E24.3 Ectopic ACTH syndrome
0.643 0.357 0.000
E24.1 Nelson's syndrome
0.643 0.357 0.000
E10.5 With peripheral circulatory complications
0.642 0.358 0.000
D50.9 Iron deficiency anaemia, unspecified
0.642 0.358 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.640 0.360 0.000
E24.8 Other Cushing's syndrome
0.639 0.360 0.000
Q03 Congenital hydrocephalus
0.639 0.361 0.000
Q63.1 Lobulated, fused and horseshoe kidney
0.638 0.362 0.000
D56 Thalassaemia
0.637 0.363 0.000
D69.0 Allergic purpura
0.636 0.364 0.000
Q44.3 Congenital stenosis and stricture of bile ducts
0.636 0.364 0.000
Q44.2 Atresia of bile ducts
0.636 0.364 0.000
Q44.1 Other congenital malformations of gallbladder
0.636 0.364 0.000
Q44.0 Agenesis, aplasia and hypoplasia of gallbladder
0.636 0.364 0.000
Q43.9 Congenital malformation of intestine, unspecified
0.634 0.366 0.000
E21.0 Primary hyperparathyroidism
0.633 0.367 0.000
E14.7 With multiple complications
0.632 0.367 0.000
E14.0 With coma
0.632 0.367 0.000
M35.9 Systemic involvement of connective tissue, unspecified
0.632 0.368 0.000
M35.6 Relapsing panniculitis [Weber-Christian]
0.632 0.368 0.000
M35.5 Multifocal fibrosclerosis
0.632 0.368 0.000
M35.4 Diffuse (eosinophilic) fasciitis
0.632 0.368 0.000
E21.2 Other hyperparathyroidism
0.631 0.368 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.632 0.368 0.000
D67 Hereditary factor IX deficiency
0.631 0.369 0.000
M33 Dermatopolymyositis
0.631 0.369 0.000
Q63.9 Congenital malformation of kidney, unspecified
0.631 0.369 0.000
H43-H45 Disorders of vitreous body and globe
0.630 0.370 0.000
E21.5 Disorder of parathyroid gland, unspecified
0.630 0.370 0.000
E24.9 Cushing's syndrome, unspecified
0.628 0.372 0.000
M24.8 Other specific joint derangements, not elsewhere classified
0.628 0.372 0.000
D64.8 Other specified anaemias
0.628 0.372 0.000
Q38.1 Ankyloglossia
0.626 0.374 0.000
N18.8 Other chronic renal failure
0.626 0.374 0.000
E27.2 Addisonian crisis
0.625 0.374 0.000
M60.9 Myositis, unspecified
0.625 0.375 0.000
E15 Nondiabetic hypoglycaemic coma
0.624 0.376 0.000
M14.6 Neuropathic arthropathy
0.000 0.377 0.623
M24.9 Joint derangement, unspecified
0.622 0.378 0.000
E03.1 Congenital hypothyroidism without goitre
0.620 0.380 0.000
Q04 Other congenital malformations of brain
0.619 0.381 0.000
M15.4 Erosive (osteo)arthrosis
0.618 0.382 0.000
H35.2 Other proliferative retinopathy
0.617 0.383 0.000
M24.11 Other articular cartilage disorders (Shoulder region)
0.616 0.384 0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.614 0.385 0.000
M63 Disorders of muscle in diseases classified elsewhere
0.614 0.386 0.000
M61 Calcification and ossification of muscle
0.614 0.386 0.000
M35.1 Other overlap syndromes
0.614 0.386 0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants
0.614 0.386 0.000
M15.8 Other polyarthrosis
0.613 0.387 0.000
M80-M85 Disorders of bone density and structure
0.612 0.388 0.000
H35.0 Background retinopathy and retinal vascular changes
0.612 0.388 0.000
H50.2 Vertical strabismus
0.611 0.389 0.000
D80.9 Immunodeficiency with predominantly antibody defects, unspecified
0.610 0.389 0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.610 0.390 0.000
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses
0.610 0.390 0.000
H34.8 Other retinal vascular occlusions
0.610 0.390 0.000
N28 Other disorders of kidney and ureter, not elsewhere classified
0.609 0.391 0.000
M23.39 Other meniscus derangements (Unspecified ligament or Unspecified meniscus)
0.607 0.392 0.000
M23.57 Chronic instability of knee (Capsular ligament)
0.607 0.393 0.000
M23.56 Chronic instability of knee (Other and unspecified lateral meniscus)
0.607 0.393 0.000
M23.55 Chronic instability of knee (Posterior horn of lateral meniscus)
0.607 0.393 0.000
M23.54 Chronic instability of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.607 0.393 0.000
M23.53 Chronic instability of knee (Medial collateral ligament or Other and unspecified medial meniscus)
0.607 0.393 0.000
M23.50 Chronic instability of knee (Multiple sites)
0.607 0.393 0.000
M90 Osteopathies in diseases classified elsewhere
0.607 0.393 0.000
E05.8 Other thyrotoxicosis
0.606 0.393 0.000
Q06 Other congenital malformations of spinal cord
0.606 0.393 0.000
Q01 Encephalocele
0.606 0.393 0.000
Q00 Anencephaly and similar malformations
0.606 0.393 0.000
Q02 Microcephaly
0.606 0.393 0.000
M87 Osteonecrosis
0.605 0.395 0.000
M15.0 Primary generalised (osteo)arthrosis
0.605 0.395 0.000
D80.1 Nonfamilial hypogammaglobulinaemia
0.604 0.396 0.000
E07.1 Dyshormogenetic goitre
0.603 0.396 0.000
E07.0 Hypersecretion of calcitonin
0.603 0.396 0.000
D52 Folate deficiency anaemia
0.603 0.397 0.000
D61.0 Constitutional aplastic anaemia
0.603 0.397 0.000
D55 Anaemia due to enzyme disorders
0.602 0.398 0.000
H03 Disorders of eyelid in diseases classified elsewhere
0.601 0.399 0.000
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.601 0.399 0.000
I00-I02 Acute rheumatic fever
0.600 0.400 0.000
H00 Hordeolum and chalazion
0.169 0.400 0.430
N28.9 Disorder of kidney and ureter, unspecified
0.600 0.400 0.000
E31.0 Autoimmune polyglandular failure
0.599 0.401 0.000
M00-M03 Infectious arthropathies
0.598 0.401 0.001
D58.9 Hereditary haemolytic anaemia, unspecified
0.598 0.402 0.000
M23.1 Discoid meniscus (congenital)
0.598 0.402 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.598 0.402 0.000
M21.8 Other specified acquired deformities of limbs
0.597 0.403 0.000
E65-E68 Obesity and other hyperalimentation
0.597 0.403 0.000
I15 Secondary hypertension
0.596 0.404 0.000
Q38.8 Other congenital malformations of pharynx
0.595 0.405 0.000
Q38.5 Congenital malformations of palate, not elsewhere classified
0.595 0.405 0.000
Q38.4 Congenital malformations of salivary glands and ducts
0.595 0.405 0.000
Q38.3 Other congenital malformations of tongue
0.595 0.405 0.000
Q38.2 Macroglossia
0.595 0.405 0.000
Q38.0 Congenital malformations of lips, not elsewhere classified
0.595 0.405 0.000
D57 Sickle-cell disorders
0.594 0.406 0.000
Q64 Other congenital malformations of urinary system
0.592 0.407 0.000
N03.8 Other
0.592 0.408 0.000
Q63.8 Other specified congenital malformations of kidney
0.592 0.408 0.000
Q63.3 Hyperplastic and giant kidney
0.592 0.408 0.000
I11.0 Hypertensive heart disease with (congestive) heart failure
0.591 0.409 0.000
M15.9 Polyarthrosis, unspecified
0.590 0.410 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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