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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs114009002
log Bayes Factor = 9.53625
Chromosome 5   position 5,784,492  (GRCh37) Explore rs114009002 on Ensembl!
Variant rs114009002 is part of Cluster X0061

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter V Mental and behavioural disorders
1.000 0.000 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.997 0.003 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.996 0.004 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.995 0.005 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.994 0.006 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.994 0.006 0.000
Chapter VI Diseases of the nervous system
0.989 0.011 0.000
F30-F39 Mood [affective] disorders
0.984 0.016 0.000
Chapter VIII Diseases of the ear and mastoid process
0.982 0.018 0.000
F10.1 Harmful use
0.981 0.019 0.000
Chapter VII Diseases of the eye and adnexa
0.980 0.020 0.000
Chapter XX External causes of morbidity and mortality
0.980 0.020 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.979 0.021 0.000
M70-M79 Other soft tissue disorders
0.971 0.029 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.967 0.033 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.962 0.038 0.000
M20-M25 Other joint disorders
0.956 0.044 0.000
F10.3 Withdrawal state
0.954 0.046 0.000
M23 Internal derangement of knee
0.950 0.050 0.000
M75 Shoulder lesions
0.949 0.051 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.945 0.055 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.934 0.066 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.934 0.066 0.000
H90-H95 Other disorders of ear
0.934 0.066 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.931 0.069 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.930 0.070 0.000
T39.1 4-Aminophenol derivatives
0.929 0.071 0.000
F32 Depressive episode
0.925 0.075 0.000
Y43 Primarily systemic agents
0.923 0.077 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.919 0.081 0.000
G40-G47 Episodic and paroxysmal disorders
0.918 0.082 0.000
Chapter IX Diseases of the circulatory system
0.917 0.083 0.000
H52 Disorders of refraction and accommodation
0.915 0.085 0.000
M75.4 Impingement syndrome of shoulder
0.914 0.086 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.913 0.087 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.911 0.089 0.000
D80-D89 Certain disorders involving the immune mechanism
0.907 0.093 0.000
T66-T78 Other and unspecified effects of external causes
0.904 0.096 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.903 0.097 0.000
Y43.3 Other antineoplastic drugs
0.901 0.099 0.000
Chapter X Diseases of the respiratory system
0.896 0.104 0.000
I60-I69 Cerebrovascular diseases
0.896 0.104 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.891 0.109 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.888 0.112 0.000
H04 Disorders of lachrymal system
0.887 0.113 0.000
T40.2 Other opioids
0.884 0.116 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.882 0.118 0.000
I69 Sequelae of cerebrovascular disease
0.881 0.119 0.000
M86-M90 Other osteopathies
0.880 0.120 0.000
G30-G32 Other degenerative diseases of the nervous system
0.880 0.120 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.880 0.120 0.000
M75.5 Bursitis of shoulder
0.877 0.123 0.000
J30-J39 Other diseases of upper respiratory tract
0.877 0.123 0.000
J34.8 Other specified disorders of nose and nasal sinuses
0.876 0.124 0.000
D86 Sarcoidosis
0.876 0.124 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.876 0.124 0.000
J34 Other disorders of nose and nasal sinuses
0.875 0.125 0.000
F31 Bipolar affective disorder
0.873 0.127 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.867 0.133 0.000
H52.2 Astigmatism
0.865 0.135 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.865 0.135 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.865 0.135 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.864 0.136 0.000
F32.3 Severe depressive episode with psychotic symptoms
0.863 0.137 0.000
G47 Sleep disorders
0.863 0.137 0.000
M23.23 Derangement of meniscus due to old tear or injury (Medial collateral ligament or Other and unspecified medial meniscus)
0.859 0.141 0.000
M23.29 Derangement of meniscus due to old tear or injury (Unspecified ligament or Unspecified meniscus)
0.850 0.150 0.000
F33 Recurrent depressive disorder
0.848 0.152 0.000
D50-D53 Nutritional anaemias
0.846 0.154 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.845 0.155 0.000
T51 Toxic effect of alcohol
0.844 0.156 0.000
S90-S99 Injuries to the ankle and foot
0.844 0.156 0.000
M23.22 Derangement of meniscus due to old tear or injury (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.843 0.157 0.000
J60-J70 Lung diseases due to external agents
0.843 0.157 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.842 0.158 0.000
Chapter II Neoplasms
0.838 0.162 0.000
W50-W64 Exposure to animate mechanical forces
0.836 0.164 0.000
H04.2 Epiphora
0.836 0.164 0.000
H49 Paralytic strabismus
0.836 0.164 0.000
I30-I52 Other forms of heart disease
0.831 0.169 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.831 0.169 0.000
F00 Dementia in Alzheimer's disease
0.828 0.172 0.000
I20-I25 Ischaemic heart diseases
0.828 0.172 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.827 0.173 0.000
I42 Cardiomyopathy
0.827 0.173 0.000
G47.9 Sleep disorder, unspecified
0.826 0.174 0.000
O42 Premature rupture of membranes
0.825 0.175 0.000
H65-H75 Diseases of middle ear and mastoid
0.824 0.176 0.000
H91 Other hearing loss
0.821 0.179 0.000
T93 Sequelae of injuries of lower limb
0.821 0.179 0.000
O42.9 Premature rupture of membranes, unspecified
0.818 0.182 0.000
F32.9 Depressive episode, unspecified
0.818 0.182 0.000
H90 Conductive and sensorineural hearing loss
0.815 0.185 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.813 0.187 0.000
I69.3 Sequelae of cerebral infarction
0.813 0.187 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.813 0.187 0.000
T78 Adverse effects, not elsewhere classified
0.811 0.189 0.000
M23.8 Other internal derangements of knee
0.811 0.189 0.000
H80-H83 Diseases of inner ear
0.807 0.193 0.000
T39.0 Salicylates
0.807 0.193 0.000
F10.0 Acute intoxication
0.807 0.193 0.000
C15-C26 Malignant neoplasms of digestive organs
0.806 0.194 0.000
Chapter XXII Codes for special purposes
0.805 0.195 0.000
F11 Mental and behavioural disorders due to use of opioids
0.803 0.197 0.000
F10.2 Dependence syndrome
0.803 0.197 0.000
J69 Pneumonitis due to solids and liquids
0.802 0.198 0.000
I42.0 Dilated cardiomyopathy
0.802 0.198 0.000
M23.3 Other meniscus derangements
0.800 0.200 0.000
H18 Other disorders of cornea
0.798 0.202 0.000
D86.9 Sarcoidosis, unspecified
0.798 0.202 0.000
H50 Other strabismus
0.798 0.202 0.000
D72 Other disorders of white blood cells
0.798 0.202 0.000
F03 Unspecified dementia
0.798 0.202 0.000
C18 Malignant neoplasm of colon
0.797 0.203 0.000
W20-W49 Exposure to inanimate mechanical forces
0.793 0.207 0.000
T90 Sequelae of injuries of head
0.792 0.208 0.000
M21 Other acquired deformities of limbs
0.792 0.208 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.788 0.212 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.787 0.213 0.000
T51.0 Ethanol
0.787 0.213 0.000
S10-S19 Injuries to the neck
0.786 0.214 0.000
G83 Other paralytic syndromes
0.784 0.216 0.000
D51 Vitamin B12 deficiency anaemia
0.783 0.217 0.000
G70-G73 Diseases of myoneural junction and muscle
0.782 0.218 0.000
H55-H59 Other disorders of eye and adnexa
0.782 0.218 0.000
H01 Other inflammation of eyelid
0.782 0.218 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.782 0.218 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.781 0.219 0.000
F10.5 Psychotic disorder
0.781 0.219 0.000
G20-G26 Extrapyramidal and movement disorders
0.780 0.220 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.778 0.222 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.777 0.223 0.000
O80-O84 Delivery
0.776 0.224 0.000
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)
0.776 0.224 0.000
O26 Maternal care for other conditions predominantly related to pregnancy
0.776 0.224 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.774 0.226 0.000
H47 Other disorders of optic [2nd] nerve and visual pathways
0.774 0.226 0.000
J69.0 Pneumonitis due to food and vomit
0.773 0.227 0.000
G30 Alzheimer's disease
0.772 0.228 0.000
H52.0 Hypermetropia
0.771 0.229 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.771 0.229 0.000
G47.8 Other sleep disorders
0.768 0.232 0.000
I22 Subsequent myocardial infarction
0.767 0.233 0.000
H60-H62 Diseases of external ear
0.767 0.233 0.000
M75.2 Bicipital tendinitis
0.764 0.236 0.000
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms
0.759 0.241 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.759 0.241 0.000
M60-M63 Disorders of muscles
0.758 0.242 0.000
H93 Other disorders of ear, not elsewhere classified
0.757 0.243 0.000
M89 Other disorders of bone
0.754 0.246 0.000
O36 Maternal care for other known or suspected foetal problems
0.751 0.249 0.000
I69.1 Sequelae of intracerebral haemorrhage
0.750 0.250 0.000
D86.0 Sarcoidosis of lung
0.750 0.250 0.000
M91-M94 Chondropathies
0.747 0.253 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.745 0.255 0.000
X60-X84 Intentional self-harm
0.744 0.256 0.000
C18.9 Colon, unspecified
0.743 0.257 0.000
I05-I09 Chronic rheumatic heart diseases
0.743 0.257 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.742 0.258 0.000
G45.9 Transient cerebral ischaemic attack, unspecified
0.741 0.259 0.000
H72 Perforation of tympanic membrane
0.741 0.259 0.000
D70 Agranulocytosis
0.740 0.260 0.000
H04.3 Acute and unspecified inflammation of lachrymal passages
0.739 0.261 0.000
F60-F69 Disorders of adult personality and behaviour
0.739 0.261 0.000
D72.8 Other specified disorders of white blood cells
0.738 0.262 0.000
V80-V89 Other land transport accidents
0.737 0.263 0.000
T92 Sequelae of injuries of upper limb
0.736 0.264 0.000
H90.4 Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
0.736 0.264 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.736 0.264 0.000
F10.4 Withdrawal state with delirium
0.735 0.264 0.000
M23.25 Derangement of meniscus due to old tear or injury (Posterior horn of lateral meniscus)
0.735 0.265 0.000
F01 Vascular dementia
0.734 0.266 0.000
J34.3 Hypertrophy of nasal turbinates
0.734 0.266 0.000
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)
0.733 0.267 0.000
Y49.2 Other and unspecified antidepressants
0.733 0.267 0.000
M71 Other bursopathies
0.733 0.267 0.000
T79-T79 Certain early complications of trauma
0.731 0.269 0.000
Y00-Y09 Assault
0.730 0.270 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.730 0.270 0.000
H81 Disorders of vestibular function
0.730 0.270 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.729 0.271 0.000
I61 Intracerebral haemorrhage
0.729 0.271 0.000
I62 Other nontraumatic intracranial haemorrhage
0.728 0.272 0.000
O36.8 Maternal care for other specified foetal problems
0.726 0.274 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.726 0.274 0.000
D86.8 Sarcoidosis of other and combined sites
0.724 0.275 0.000
H10-H13 Disorders of conjunctiva
0.724 0.276 0.000
V10-V19 Pedal cyclist injured in transport accident
0.724 0.276 0.000
H05 Disorders of orbit
0.724 0.276 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.723 0.276 0.000
I42.1 Obstructive hypertrophic cardiomyopathy
0.723 0.277 0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression
0.722 0.278 0.000
T68 Hypothermia
0.722 0.278 0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.720 0.280 0.000
T93.9 Sequelae of unspecified injury of lower limb
0.720 0.280 0.000
F00.9 Dementia in Alzheimer's disease, unspecified
0.720 0.280 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.720 0.280 0.000
O85-O92 Complications predominantly related to the puerperium
0.718 0.282 0.000
Y43.4 Immunosuppressive agents
0.718 0.282 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.717 0.283 0.000
F70-F79 Mental retardation
0.717 0.283 0.000
M75.3 Calcific tendinitis of shoulder
0.716 0.284 0.000
M23.0 Cystic meniscus
0.716 0.284 0.000
G83.4 Cauda equina syndrome
0.716 0.284 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.715 0.285 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.715 0.285 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.715 0.285 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.715 0.285 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.715 0.285 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.715 0.285 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.715 0.285 0.000
F10.9 Unspecified mental and behavioural disorder
0.714 0.286 0.000
F10.8 Other mental and behavioural disorders
0.714 0.286 0.000
F10.7 Residual and late-onset psychotic disorder
0.714 0.286 0.000
F10.6 Amnesic syndrome
0.714 0.286 0.000
M15-M19 Arthrosis
0.714 0.286 0.000
Y44 Agents primarily affecting blood constituents
0.714 0.286 0.000
I51 Complications and ill-defined descriptions of heart disease
0.714 0.286 0.000
T33-T35 Frostbite
0.713 0.286 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.713 0.286 0.000
T00-T07 Injuries involving multiple body regions
0.713 0.286 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.713 0.287 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.713 0.287 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.713 0.287 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.713 0.287 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.713 0.287 0.000
T36 Poisoning by systemic antibiotics
0.713 0.287 0.000
O26.8 Other specified pregnancy-related conditions
0.712 0.288 0.000
T78.3 Angioneurotic oedema
0.712 0.288 0.000
G62 Other polyneuropathies
0.712 0.288 0.000
M87 Osteonecrosis
0.710 0.290 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.710 0.290 0.000
F31.6 Bipolar affective disorder, current episode mixed
0.710 0.290 0.000
I67 Other cerebrovascular diseases
0.709 0.291 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.709 0.291 0.000
X50-X57 Overexertion, travel and privation
0.708 0.292 0.000
M30 Polyarteritis nodosa and related conditions
0.707 0.293 0.000
I42.2 Other hypertrophic cardiomyopathy
0.706 0.294 0.000
D55-D59 Haemolytic anaemias
0.706 0.294 0.000
C18.7 Sigmoid colon
0.705 0.295 0.000
F38 Other mood [affective] disorders
0.705 0.295 0.000
F34 Persistent mood [affective] disorders
0.705 0.295 0.000
F39 Unspecified mood [affective] disorder
0.705 0.295 0.000
H74 Other disorders of middle ear and mastoid
0.705 0.295 0.000
J34.1 Cyst and mucocele of nose and nasal sinus
0.704 0.296 0.000
M00-M03 Infectious arthropathies
0.704 0.296 0.000
Q60-Q64 Congenital malformations of the urinary system
0.704 0.296 0.000
G44 Other headache syndromes
0.704 0.296 0.000
W22 Striking against or struck by other objects
0.703 0.297 0.000
H18.5 Hereditary corneal dystrophies
0.703 0.297 0.000
Y35-Y36 Legal intervention and operations of war
0.702 0.297 0.000
Y10-Y34 Event of undetermined intent
0.702 0.297 0.000
X85-X99 Assault
0.702 0.297 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.702 0.297 0.000
X30-X39 Exposure to forces of nature
0.702 0.297 0.000
X10-X19 Contact with heat and hot substances
0.702 0.297 0.000
X00-X09 Exposure to smoke, fire and flames
0.702 0.297 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.702 0.297 0.000
W75-W84 Other accidental threats to breathing
0.702 0.297 0.000
W65-W74 Accidental drowning and submersion
0.702 0.297 0.000
V98-V99 Other and unspecified transport accidents
0.702 0.297 0.000
V95-V97 Air and space transport accidents
0.702 0.297 0.000
V90-V94 Water transport accidents
0.702 0.297 0.000
V70-V79 Bus occupant injured in transport accident
0.702 0.297 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.702 0.297 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.702 0.297 0.000
V40-V49 Car occupant injured in transport accident
0.702 0.297 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.702 0.297 0.000
V01-V09 Pedestrian injured in transport accident
0.702 0.297 0.000
Chapter XXI Factors influencing health status and contact with health services
0.702 0.298 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.702 0.298 0.000
T39.4 Antirheumatics, not elsewhere classified
0.702 0.298 0.000
T39.2 Pyrazolone derivatives
0.702 0.298 0.000
F30 Manic episode
0.700 0.299 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.700 0.299 0.000
M23.4 Loose body in knee
0.699 0.301 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.698 0.301 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.698 0.302 0.000
G80 Infantile cerebral palsy
0.698 0.302 0.000
T56 Toxic effect of metals
0.698 0.302 0.000
F02 Dementia in other diseases classified elsewhere
0.697 0.302 0.000
O80 Single spontaneous delivery
0.697 0.303 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.697 0.303 0.000
M22 Disorders of patella
0.696 0.303 0.000
M76 Enthesopathies of lower limb, excluding foot
0.696 0.304 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.696 0.304 0.000
C44 Other malignant neoplasms of skin
0.696 0.304 0.000
G30.9 Alzheimer's disease, unspecified
0.696 0.304 0.000
M96.1 Postlaminectomy syndrome, not elsewhere classified
0.695 0.305 0.000
I20 Angina pectoris
0.695 0.305 0.000
H46 Optic neuritis
0.695 0.305 0.000
M96.0 Pseudarthrosis after fusion or arthrodesis
0.694 0.306 0.000
H49.9 Paralytic strabismus, unspecified
0.693 0.307 0.000
H91.9 Hearing loss, unspecified
0.693 0.307 0.000
D73 Diseases of spleen
0.693 0.307 0.000
G82 Paraplegia and tetraplegia
0.693 0.307 0.000
Y52 Agents primarily affecting the cardiovascular system
0.692 0.307 0.000
I22.1 Subsequent myocardial infarction of inferior wall
0.692 0.308 0.000
Y49.5 Other antipsychotics and neuroleptics
0.692 0.308 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.692 0.308 0.000
M23.9 Internal derangement of knee, unspecified
0.691 0.308 0.000
T40.6 Other and unspecified narcotics
0.690 0.310 0.000
H04.4 Chronic inflammation of lachrymal passages
0.690 0.310 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.690 0.310 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.690 0.310 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.689 0.310 0.000
H51 Other disorders of binocular movement
0.689 0.310 0.000
M80-M85 Disorders of bone density and structure
0.689 0.311 0.000
C18.6 Descending colon
0.688 0.312 0.000
I69.0 Sequelae of subarachnoid haemorrhage
0.688 0.312 0.000
M23.83 Other internal derangements of knee (Medial collateral ligament or Other and unspecified medial meniscus)
0.687 0.313 0.000
I37 Pulmonary valve disorders
0.687 0.313 0.000
H50.9 Strabismus, unspecified
0.686 0.314 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.685 0.315 0.000
M33 Dermatopolymyositis
0.685 0.315 0.000
M32 Systemic lupus erythematosus
0.685 0.315 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.685 0.315 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.685 0.315 0.000
M90 Osteopathies in diseases classified elsewhere
0.685 0.315 0.000
W55 Bitten or struck by other mammals
0.683 0.317 0.000
M77 Other enthesopathies
0.683 0.317 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.682 0.318 0.000
Y43.1 Antineoplastic antimetabolites
0.682 0.318 0.000
M23.1 Discoid meniscus (congenital)
0.681 0.319 0.000
F05 Delirium, not induced by alcohol and other psychoactive substances
0.681 0.319 0.000
M75.8 Other shoulder lesions
0.681 0.319 0.000
M75.9 Shoulder lesion, unspecified
0.681 0.319 0.000
J39 Other diseases of upper respiratory tract
0.680 0.320 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.679 0.321 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.679 0.321 0.000
W57 Bitten or stung by non-venomous insect and other non-venomous arthropods
0.678 0.322 0.000
Y59 Other and unspecified vaccines and biological substances
0.677 0.322 0.000
Y58 Bacterial vaccines
0.677 0.322 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.677 0.322 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.677 0.322 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.677 0.322 0.000
Y48 Anaesthetics and therapeutic gases
0.677 0.322 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.677 0.322 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.677 0.322 0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms
0.677 0.323 0.000
Q80-Q89 Other congenital malformations
0.677 0.323 0.000
V20-V29 Motorcycle rider injured in transport accident
0.676 0.323 0.000
H91.8 Other specified hearing loss
0.676 0.324 0.000
T58 Toxic effect of carbon monoxide
0.674 0.326 0.000
O20 Haemorrhage in early pregnancy
0.674 0.326 0.000
J90-J94 Other diseases of pleura
0.673 0.327 0.000
M45-M49 Spondylopathies
0.672 0.328 0.000
M79.7 Fibromyalgia
0.671 0.329 0.000
T93.5 Sequelae of injury of muscle and tendon of lower limb
0.670 0.330 0.000
M23.89 Other internal derangements of knee (Unspecified ligament or Unspecified meniscus)
0.670 0.330 0.000
M23.27 Derangement of meniscus due to old tear or injury-Capsular
0.670 0.330 0.000
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction
0.670 0.330 0.000
F09 Unspecified organic or symptomatic mental disorder
0.670 0.330 0.000
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances
0.670 0.330 0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified
0.670 0.330 0.000
H94 Other disorders of ear in diseases classified elsewhere
0.670 0.330 0.000
X20-X29 Contact with venomous animals and plants
0.669 0.331 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.669 0.331 0.000
I44 Atrioventricular and left bundle-branch block
0.669 0.331 0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]
0.667 0.332 0.000
T40.8 Lysergide [LSD]
0.667 0.332 0.000
T40.7 Cannabis (derivatives)
0.667 0.332 0.000
T40.5 Cocaine
0.667 0.332 0.000
T40.3 Methadone
0.667 0.332 0.000
T40.1 Heroin
0.667 0.332 0.000
T40.0 Opium
0.667 0.332 0.000
M40-M43 Deforming dorsopathies
0.667 0.332 0.000
H92 Otalgia and effusion of ear
0.667 0.333 0.000
T95 Sequelae of burns, corrosions and frostbite
0.667 0.333 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.667 0.333 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.667 0.333 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.667 0.333 0.000
H52.3 Anisometropia and aniseikonia
0.667 0.333 0.000
C44.3 Skin of other and unspecified parts of face
0.666 0.334 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.666 0.334 0.000
G60 Hereditary and idiopathic neuropathy
0.664 0.336 0.000
F00.0 Dementia in Alzheimer's disease with early onset
0.664 0.336 0.000
F11.2 Dependence syndrome
0.664 0.336 0.000
S91 Open wound of ankle and foot
0.664 0.336 0.000
F32.8 Other depressive episodes
0.663 0.336 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.663 0.337 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.663 0.337 0.000
T59 Toxic effect of other gases, fumes and vapours
0.662 0.338 0.000
Q00-Q07 Congenital malformations of the nervous system
0.662 0.338 0.000
Y43.9 Primarily systemic agent, unspecified
0.662 0.338 0.000
Y43.8 Other primarily systemic agents, not elsewhere classified
0.662 0.338 0.000
Y43.6 Enzymes, not elsewhere classified
0.662 0.338 0.000
Y43.5 Acidifying and alkalising agents
0.662 0.338 0.000
Y43.2 Antineoplastic natural products
0.662 0.338 0.000
Y43.0 Antiallergic and antiemetic drugs
0.662 0.338 0.000
F32.2 Severe depressive episode without psychotic symptoms
0.661 0.339 0.000
M89.9 Disorder of bone, unspecified
0.661 0.339 0.000
H01.0 Blepharitis
0.660 0.340 0.000
H69 Other disorders of Eustachian tube
0.659 0.341 0.000
I05 Rheumatic mitral valve diseases
0.659 0.341 0.000
O80.9 Single spontaneous delivery, unspecified
0.659 0.341 0.000
T98 Sequelae of other and unspecified effects of external causes
0.659 0.341 0.000
M21.0 Valgus deformity, not elsewhere classified
0.659 0.341 0.000
H03 Disorders of eyelid in diseases classified elsewhere
0.659 0.341 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.658 0.342 0.000
G41 Status epilepticus
0.658 0.342 0.000
T78.4 Allergy, unspecified
0.658 0.342 0.000
H72.9 Perforation of tympanic membrane, unspecified
0.658 0.342 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.658 0.342 0.000
I00-I02 Acute rheumatic fever
0.658 0.342 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.657 0.343 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.657 0.343 0.000
H04.1 Other disorders of lachrymal gland
0.657 0.343 0.000
I20.9 Angina pectoris, unspecified
0.657 0.343 0.000
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms
0.657 0.343 0.000
M24 Other specific joint derangements
0.656 0.344 0.000
H49.2 Sixth [abducent] nerve palsy
0.656 0.344 0.000
H52.7 Disorder of refraction, unspecified
0.656 0.344 0.000
H52.6 Other disorders of refraction
0.656 0.344 0.000
H52.5 Disorders of accommodation
0.656 0.344 0.000
H52.4 Presbyopia
0.656 0.344 0.000
T90.9 Sequelae of unspecified injury of head
0.656 0.344 0.000
C18.0 Caecum
0.655 0.345 0.000
D86.1 Sarcoidosis of lymph nodes
0.655 0.345 0.000
T43.9 Psychotropic drug, unspecified
0.654 0.345 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.654 0.345 0.000
T43.6 Psychostimulants with abuse potential
0.654 0.345 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.654 0.345 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.654 0.345 0.000
C21 Malignant neoplasm of anus and anal canal
0.654 0.346 0.000
M19 Other arthrosis
0.654 0.346 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.654 0.346 0.000
T65 Toxic effect of other and unspecified substances
0.653 0.347 0.000
T62 Toxic effect of other noxious substances eaten as food
0.653 0.347 0.000
T61 Toxic effect of noxious substances eaten as seafood
0.653 0.347 0.000
T60 Toxic effect of pesticides
0.653 0.347 0.000
T57 Toxic effect of other inorganic substances
0.653 0.347 0.000
T54 Toxic effect of corrosive substances
0.653 0.347 0.000
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone
0.653 0.347 0.000
T52 Toxic effect of organic solvents
0.653 0.347 0.000
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants
0.653 0.347 0.000
T55 Toxic effect of soaps and detergents
0.653 0.347 0.000
M31 Other necrotising vasculopathies
0.653 0.347 0.000
F32.1 Moderate depressive episode
0.653 0.347 0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.652 0.348 0.000
T93.8 Sequelae of other specified injuries of lower limb
0.651 0.348 0.000
I51.8 Other ill-defined heart diseases
0.651 0.349 0.000
M23.24 Derangement of meniscus due to old tear or injury (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.651 0.349 0.000
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care
0.650 0.350 0.000
D84 Other immunodeficiencies
0.650 0.350 0.000
D83 Common variable immunodeficiency
0.650 0.350 0.000
D82 Immunodeficiency associated with other major defects
0.650 0.350 0.000
D81 Combined immunodeficiencies
0.650 0.350 0.000
T40.4 Other synthetic narcotics
0.649 0.351 0.000
T75 Effects of other external causes
0.648 0.352 0.000
T74 Maltreatment syndromes
0.648 0.352 0.000
T73 Effects of other deprivation
0.648 0.352 0.000
T70 Effects of air pressure and water pressure
0.648 0.352 0.000
T69 Other effects of reduced temperature
0.648 0.352 0.000
T67 Effects of heat and light
0.648 0.352 0.000
T71 Asphyxiation
0.648 0.352 0.000
T66 Unspecified effects of radiation
0.648 0.352 0.000
C18.4 Transverse colon
0.648 0.352 0.000
S90 Superficial injury of ankle and foot
0.647 0.353 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.647 0.353 0.000
H49.1 Fourth [trochlear] nerve palsy
0.646 0.354 0.000
T91 Sequelae of injuries of neck and trunk
0.646 0.354 0.000
T51.9 Alcohol, unspecified
0.646 0.354 0.000
M79.8 Other specified soft tissue disorders
0.645 0.355 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.645 0.355 0.000
H47.2 Optic atrophy
0.645 0.355 0.000
D80 Immunodeficiency with predominantly antibody defects
0.644 0.356 0.000
G72 Other myopathies
0.643 0.357 0.000
Chapter I Certain infectious and parasitic diseases
0.643 0.357 0.000
C44.0 Skin of lip
0.643 0.357 0.000
M23.30 Other meniscus derangements (Multiple sites)
0.643 0.357 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.642 0.358 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.642 0.358 0.000
I45 Other conduction disorders
0.642 0.358 0.000
G47.0 Disorders of initiating and maintaining sleep [insomnias]
0.642 0.358 0.000
M79.1 Myalgia
0.641 0.359 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.640 0.360 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.640 0.360 0.000
Y79 Orthopaedic devices associated with adverse incidents
0.639 0.361 0.000
W22.9 Unspecified place
0.639 0.361 0.000
M99 Biomechanical lesions, not elsewhere classified
0.639 0.361 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.638 0.362 0.000
O23 Infections of genito-urinary tract in pregnancy
0.637 0.362 0.000
M75.1 Rotator cuff syndrome
0.637 0.363 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.637 0.363 0.000
T90.5 Sequelae of intracranial injury
0.637 0.363 0.000
F31.0 Bipolar affective disorder, current episode hypomanic
0.637 0.363 0.000
I42.8 Other cardiomyopathies
0.636 0.364 0.000
F99-F99 Unspecified mental disorder
0.636 0.364 0.000
F80-F89 Disorders of psychological development
0.636 0.364 0.000
H18.8 Other specified disorders of cornea
0.636 0.364 0.000
H04.9 Disorder of lachrymal system, unspecified
0.636 0.364 0.000
H04.6 Other changes in lachrymal passages
0.636 0.364 0.000
H04.0 Dacryoadenitis
0.636 0.364 0.000
H04.8 Other disorders of lachrymal system
0.636 0.364 0.000
M79.6 Pain in limb
0.635 0.365 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.635 0.365 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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