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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs114188741
log Bayes Factor = 17.6434
Chromosome 4   position 136,403,342  (GRCh37) Explore rs114188741 on Ensembl!
Variant rs114188741 is part of Cluster X0146

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
1.000 0.000 0.000
Chapter VII Diseases of the eye and adnexa
1.000 0.000 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.999 0.001 0.000
Chapter X Diseases of the respiratory system
0.996 0.004 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.996 0.004 0.000
H30-H36 Disorders of choroid and retina
0.993 0.007 0.000
S00-S09 Injuries to the head
0.992 0.008 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.991 0.009 0.000
Chapter VI Diseases of the nervous system
0.991 0.009 0.000
Chapter V Mental and behavioural disorders
0.987 0.013 0.000
Chapter II Neoplasms
0.985 0.015 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.983 0.017 0.000
H33 Retinal detachments and breaks
0.983 0.017 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.979 0.021 0.000
G90-G99 Other disorders of the nervous system
0.979 0.021 0.000
Chapter XXI Factors influencing health status and contact with health services
0.979 0.021 0.000
R50-R69 General symptoms and signs
0.975 0.025 0.000
H00 Hordeolum and chalazion
0.973 0.027 0.000
S01 Open wound of head
0.971 0.029 0.000
Chapter I Certain infectious and parasitic diseases
0.971 0.029 0.000
S01.8 Open wound of other parts of head
0.959 0.041 0.000
Chapter XIV Diseases of the genitourinary system
0.958 0.042 0.000
H00.1 Chalazion
0.954 0.046 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.954 0.046 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.954 0.046 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.953 0.047 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.951 0.049 0.000
J60-J70 Lung diseases due to external agents
0.951 0.049 0.000
N10-N16 Renal tubulo-interstitial diseases
0.949 0.051 0.000
H33.3 Retinal breaks without detachment
0.948 0.052 0.000
C79 Secondary malignant neoplasm of other sites
0.946 0.054 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.946 0.054 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.946 0.054 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.945 0.055 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.941 0.059 0.000
Z51 Other medical care
0.938 0.062 0.000
N13 Obstructive and reflux uropathy
0.936 0.064 0.000
H33.0 Retinal detachment with retinal break
0.936 0.064 0.000
J09-J18 Influenza and pneumonia
0.936 0.064 0.000
R29.6 Tendency to fall, not elsewhere classified
0.932 0.068 0.000
H02 Other disorders of eyelid
0.930 0.070 0.000
Z50 Care involving use of rehabilitation procedures
0.927 0.073 0.000
J90-J94 Other diseases of pleura
0.924 0.076 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.924 0.076 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.919 0.081 0.000
N20-N23 Urolithiasis
0.914 0.086 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.914 0.086 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.914 0.086 0.000
S50-S59 Injuries to the elbow and forearm
0.913 0.087 0.000
R53 Malaise and fatigue
0.908 0.092 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.907 0.093 0.000
R91 Abnormal findings on diagnostic imaging of lung
0.906 0.094 0.000
R26 Abnormalities of gait and mobility
0.904 0.096 0.000
R59 Enlarged lymph nodes
0.903 0.097 0.000
R52 Pain, not elsewhere classified
0.903 0.097 0.000
H34 Retinal vascular occlusions
0.902 0.098 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.900 0.100 0.000
C51-C58 Malignant neoplasms of female genital organs
0.899 0.101 0.000
Z51.0 Radiotherapy session
0.898 0.102 0.000
S02 Fracture of skull and facial bones
0.894 0.106 0.000
J69 Pneumonitis due to solids and liquids
0.893 0.107 0.000
Z51.5 Palliative care
0.886 0.114 0.000
C78.2 Secondary malignant neoplasm of pleura
0.881 0.119 0.000
F30-F39 Mood [affective] disorders
0.879 0.121 0.000
H43-H45 Disorders of vitreous body and globe
0.875 0.125 0.000
Chapter XI Diseases of the digestive system
0.874 0.126 0.000
H04 Disorders of lachrymal system
0.872 0.128 0.000
Chapter XX External causes of morbidity and mortality
0.872 0.128 0.000
C78.0 Secondary malignant neoplasm of lung
0.870 0.130 0.000
D69 Purpura and other haemorrhagic conditions
0.868 0.131 0.000
K70-K77 Diseases of liver
0.868 0.132 0.000
R59.1 Generalised enlarged lymph nodes
0.863 0.137 0.000
J90 Pleural effusion, not elsewhere classified
0.863 0.137 0.000
R44.3 Hallucinations, unspecified
0.863 0.137 0.000
C77.0 Lymph nodes of head, face and neck
0.862 0.138 0.000
Z51.8 Other specified medical care
0.861 0.139 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.860 0.140 0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified
0.860 0.140 0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction
0.860 0.140 0.000
R60 Oedema, not elsewhere classified
0.859 0.141 0.000
R25 Abnormal involuntary movements
0.856 0.144 0.000
G91 Hydrocephalus
0.853 0.147 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.852 0.148 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.852 0.148 0.000
J69.0 Pneumonitis due to food and vomit
0.851 0.149 0.000
N13.3 Other and unspecified hydronephrosis
0.842 0.158 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.842 0.158 0.000
R26.8 Other and unspecified abnormalities of gait and mobility
0.841 0.159 0.000
K70 Alcoholic liver disease
0.840 0.160 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.839 0.161 0.000
R41.3 Other amnesia
0.838 0.162 0.000
H55-H59 Other disorders of eye and adnexa
0.836 0.164 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.835 0.165 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.833 0.167 0.000
G95 Other diseases of spinal cord
0.833 0.167 0.000
J95-J99 Other diseases of the respiratory system
0.833 0.167 0.000
O60-O75 Complications of labour and delivery
0.833 0.167 0.000
R40 Somnolence, stupor and coma
0.832 0.168 0.000
N20 Calculus of kidney and ureter
0.832 0.168 0.000
S50 Superficial injury of forearm
0.831 0.169 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.830 0.170 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.830 0.170 0.000
H01 Other inflammation of eyelid
0.827 0.173 0.000
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified
0.827 0.173 0.000
D69.6 Thrombocytopenia, unspecified
0.826 0.174 0.000
H02.9 Disorder of eyelid, unspecified
0.825 0.175 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.825 0.175 0.000
G20-G26 Extrapyramidal and movement disorders
0.825 0.175 0.000
F05 Delirium, not induced by alcohol and other psychoactive substances
0.825 0.175 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.823 0.177 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.823 0.177 0.000
B35-B49 Mycoses
0.822 0.178 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.820 0.180 0.000
F01 Vascular dementia
0.820 0.180 0.000
A80-A89 Viral infections of the central nervous system
0.819 0.181 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.819 0.181 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.819 0.181 0.000
R44.1 Visual hallucinations
0.817 0.183 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.817 0.183 0.000
R47-R49 Symptoms and signs involving speech and voice
0.813 0.187 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.812 0.188 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.811 0.189 0.000
R94 Abnormal results of function studies
0.809 0.191 0.000
J00-J06 Acute upper respiratory infections
0.809 0.191 0.000
S20-S29 Injuries to the thorax
0.808 0.192 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.808 0.192 0.000
S06 Intracranial injury
0.808 0.192 0.000
K70.9 Alcoholic liver disease, unspecified
0.804 0.196 0.000
B15-B19 Viral hepatitis
0.803 0.197 0.000
G90 Disorders of autonomic nervous system
0.803 0.197 0.000
J61 Pneumoconiosis due to asbestos and other mineral fibres
0.800 0.200 0.000
H34.8 Other retinal vascular occlusions
0.800 0.200 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.799 0.201 0.000
H05 Disorders of orbit
0.799 0.201 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.799 0.201 0.000
D50-D53 Nutritional anaemias
0.796 0.204 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.796 0.204 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.796 0.204 0.000
Z73 Problems related to life-management difficulty
0.796 0.204 0.000
Z50.4 Psychotherapy, not elsewhere classified
0.795 0.205 0.000
N23 Unspecified renal colic
0.794 0.206 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.794 0.206 0.000
F41 Other anxiety disorders
0.792 0.208 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.791 0.208 0.000
R61 Hyperhidrosis
0.791 0.209 0.000
R60.0 Localised oedema
0.788 0.212 0.000
R56 Convulsions, not elsewhere classified
0.787 0.213 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.786 0.214 0.000
R06 Abnormalities of breathing
0.785 0.215 0.000
H02.8 Other specified disorders of eyelid
0.784 0.216 0.000
Z42 Follow-up care involving plastic surgery
0.783 0.217 0.000
S10-S19 Injuries to the neck
0.782 0.218 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.782 0.218 0.000
S00 Superficial injury of head
0.781 0.219 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.781 0.219 0.000
O72 Postpartum haemorrhage
0.781 0.219 0.000
J18 Pneumonia, organism unspecified
0.779 0.221 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.778 0.222 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.777 0.223 0.000
N13.9 Obstructive and reflux uropathy, unspecified
0.777 0.223 0.000
F03 Unspecified dementia
0.776 0.224 0.000
R52.1 Chronic intractable pain
0.776 0.224 0.000
S09 Other and unspecified injuries of head
0.775 0.225 0.000
K90-K93 Other diseases of the digestive system
0.775 0.225 0.000
Z50.8 Care involving use of rehabilitation procedures
0.774 0.226 0.000
H02.4 Ptosis of eyelid
0.774 0.226 0.000
J17 Pneumonia in diseases classified elsewhere
0.772 0.228 0.000
S01.9 Open wound of head, part unspecified
0.771 0.229 0.000
G96 Other disorders of central nervous system
0.770 0.230 0.000
R13 Dysphagia
0.770 0.230 0.000
S01.2 Open wound of nose
0.769 0.231 0.000
G70-G73 Diseases of myoneural junction and muscle
0.769 0.231 0.000
Z50.1 Other physical therapy
0.767 0.233 0.000
H43 Disorders of vitreous body
0.766 0.234 0.000
F99-F99 Unspecified mental disorder
0.765 0.234 0.000
C53 Malignant neoplasm of cervix uteri
0.765 0.235 0.000
G93 Other disorders of brain
0.764 0.236 0.000
C56 Malignant neoplasm of ovary
0.760 0.240 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.758 0.242 0.000
B99-B99 Other infectious diseases
0.758 0.242 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.757 0.243 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.754 0.246 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.754 0.246 0.000
R52.9 Pain, unspecified
0.753 0.247 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.753 0.247 0.000
J20-J22 Other acute lower respiratory infections
0.752 0.248 0.000
Z71.1 Person with feared complaint in whom no diagnosis is made
0.751 0.249 0.000
N99-N99 Other disorders of the genitourinary system
0.749 0.251 0.000
F33 Recurrent depressive disorder
0.749 0.251 0.000
Z50.9 Care involving use of rehabilitation procedure, unspecified
0.748 0.252 0.000
K76 Other diseases of liver
0.747 0.253 0.000
R03 Abnormal blood-pressure reading, without diagnosis
0.747 0.253 0.000
H10-H13 Disorders of conjunctiva
0.747 0.253 0.000
S01.4 Open wound of cheek and temporomandibular area
0.747 0.253 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.745 0.255 0.000
G51 Facial nerve disorders
0.744 0.256 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.742 0.258 0.000
C81 Hodgkin's disease
0.742 0.258 0.000
M45-M49 Spondylopathies
0.741 0.259 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.740 0.259 0.000
R41.0 Disorientation, unspecified
0.739 0.261 0.000
F05.9 Delirium, unspecified
0.738 0.262 0.000
R44.0 Auditory hallucinations
0.738 0.262 0.000
G83 Other paralytic syndromes
0.738 0.262 0.000
R59.9 Enlarged lymph nodes, unspecified
0.737 0.262 0.000
H34.2 Other retinal artery occlusions
0.737 0.263 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.735 0.265 0.000
R06.5 Mouth breathing
0.735 0.265 0.000
Z74 Problems related to care-provider dependency
0.734 0.265 0.000
G20 Parkinson's disease
0.734 0.266 0.000
H55 Nystagmus and other irregular eye movements
0.733 0.267 0.000
S51 Open wound of forearm
0.732 0.268 0.000
J11 Influenza, virus not identified
0.731 0.269 0.000
H35 Other retinal disorders
0.730 0.270 0.000
Z71.2 Person consulting for explanation of investigation findings
0.730 0.270 0.000
J98 Other respiratory disorders
0.730 0.270 0.000
F01.9 Vascular dementia, unspecified
0.730 0.270 0.000
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified
0.729 0.270 0.000
J91 Pleural effusion in conditions classified elsewhere
0.729 0.270 0.000
Z51.9 Medical care, unspecified
0.729 0.271 0.000
G91.9 Hydrocephalus, unspecified
0.729 0.271 0.000
G97.1 Other reaction to spinal and lumbar puncture
0.728 0.272 0.000
F41.9 Anxiety disorder, unspecified
0.728 0.272 0.000
R68 Other general symptoms and signs
0.728 0.272 0.000
S70-S79 Injuries to the hip and thigh
0.728 0.272 0.000
R25.8 Other and unspecified abnormal involuntary movements
0.727 0.273 0.000
Q76 Congenital malformations of spine and bony thorax
0.726 0.274 0.000
O72.1 Other immediate postpartum haemorrhage
0.725 0.275 0.000
Q50-Q56 Congenital malformations of genital organs
0.723 0.277 0.000
K72 Hepatic failure, not elsewhere classified
0.722 0.277 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.722 0.278 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.721 0.278 0.000
F60-F69 Disorders of adult personality and behaviour
0.721 0.279 0.000
R18 Ascites
0.720 0.280 0.000
N13.4 Hydroureter
0.719 0.281 0.000
S90-S99 Injuries to the ankle and foot
0.719 0.281 0.000
Q00-Q07 Congenital malformations of the nervous system
0.719 0.281 0.000
S00.0 Superficial injury of scalp
0.719 0.281 0.000
R15 Faecal incontinence
0.719 0.281 0.000
R40.0 Somnolence
0.719 0.281 0.000
K35-K38 Diseases of appendix
0.718 0.282 0.000
H04.2 Epiphora
0.718 0.282 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.717 0.283 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.717 0.283 0.000
T66-T78 Other and unspecified effects of external causes
0.716 0.284 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.716 0.284 0.000
H03 Disorders of eyelid in diseases classified elsewhere
0.716 0.284 0.000
R41.8 Other and unspecified symptoms and signs involving cognitive functions and awareness
0.716 0.284 0.000
Z71.8 Other specified counselling
0.715 0.285 0.000
S02.0 Fracture of vault of skull
0.715 0.285 0.000
B25-B34 Other viral diseases
0.714 0.285 0.000
T79-T79 Certain early complications of trauma
0.714 0.286 0.000
H00.0 Hordeolum and other deep inflammation of eyelid
0.714 0.286 0.000
T33-T35 Frostbite
0.714 0.286 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.714 0.286 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.714 0.286 0.000
T00-T07 Injuries involving multiple body regions
0.714 0.286 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.713 0.287 0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease
0.713 0.287 0.000
A63 Other predominantly sexually transmitted diseases, not elsewhere classified
0.713 0.287 0.000
Z54 Convalescence
0.712 0.288 0.000
H02.0 Entropion and trichiasis of eyelid
0.712 0.288 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.712 0.288 0.000
H31 Other disorders of choroid
0.712 0.288 0.000
H30 Chorioretinal inflammation
0.712 0.288 0.000
S08 Traumatic amputation of part of head
0.711 0.289 0.000
S07 Crushing injury of head
0.711 0.289 0.000
S05 Injury of eye and orbit
0.711 0.289 0.000
S04 Injury of cranial nerves
0.711 0.289 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.711 0.289 0.000
N25-N29 Other disorders of kidney and ureter
0.711 0.289 0.000
F30 Manic episode
0.711 0.289 0.000
H43.3 Other vitreous opacities
0.710 0.290 0.000
K65-K67 Diseases of peritoneum
0.709 0.290 0.000
M20-M25 Other joint disorders
0.709 0.291 0.000
Y43 Primarily systemic agents
0.709 0.291 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.708 0.292 0.000
F80-F89 Disorders of psychological development
0.708 0.292 0.000
F70-F79 Mental retardation
0.708 0.292 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.708 0.292 0.000
G95.9 Disease of spinal cord, unspecified
0.708 0.292 0.000
H40-H42 Glaucoma
0.708 0.292 0.000
C77.8 Lymph nodes of multiple regions
0.707 0.292 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.707 0.293 0.000
W00-W19 Falls
0.707 0.293 0.000
B44 Aspergillosis
0.707 0.293 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.706 0.293 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.706 0.293 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.706 0.293 0.000
C79.2 Secondary malignant neoplasm of skin
0.706 0.294 0.000
G03 Meningitis due to other and unspecified causes
0.706 0.294 0.000
N13.5 Kinking and stricture of ureter without hydronephrosis
0.705 0.295 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.705 0.295 0.000
H33.5 Other retinal detachments
0.705 0.295 0.000
H33.4 Traction detachment of retina
0.705 0.295 0.000
H33.1 Retinoschisis and retinal cysts
0.705 0.295 0.000
H01.0 Blepharitis
0.705 0.295 0.000
J10 Influenza due to identified influenza virus
0.705 0.295 0.000
N21 Calculus of lower urinary tract
0.704 0.296 0.000
H02.5 Other disorders affecting eyelid function
0.704 0.296 0.000
Z36 Antenatal screening
0.703 0.297 0.000
R46 Symptoms and signs involving appearance and behaviour
0.702 0.298 0.000
R43 Disturbances of smell and taste
0.702 0.298 0.000
F41.0 Panic disorder [episodic paroxysmal anxiety]
0.702 0.298 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.702 0.298 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.702 0.298 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.702 0.298 0.000
G92 Toxic encephalopathy
0.702 0.298 0.000
R03.0 Elevated blood-pressure reading, without diagnosis of hypertension
0.702 0.298 0.000
S02.4 Fracture of malar and maxillary bones
0.701 0.299 0.000
N20.0 Calculus of kidney
0.700 0.299 0.000
S01.0 Open wound of scalp
0.700 0.300 0.000
C34 Malignant neoplasm of bronchus and lung
0.699 0.301 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.699 0.301 0.000
R62 Lack of expected normal physiological development
0.699 0.301 0.000
R64 Cachexia
0.699 0.301 0.000
R58 Haemorrhage, not elsewhere classified
0.699 0.301 0.000
A30-A49 Other bacterial diseases
0.699 0.301 0.000
R57 Shock, not elsewhere classified
0.698 0.302 0.000
M86-M90 Other osteopathies
0.698 0.302 0.000
H04.5 Stenosis and insufficiency of lachrymal passages
0.698 0.302 0.000
S01.7 Multiple open wounds of head
0.696 0.303 0.000
D69.3 Idiopathic thrombocytopenic purpura
0.696 0.304 0.000
S50.8 Other superficial injuries of forearm
0.696 0.304 0.000
O75.6 Delayed delivery after spontaneous or unspecified rupture of membranes
0.696 0.304 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.696 0.304 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.696 0.304 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.696 0.304 0.000
B65-B83 Helminthiases
0.696 0.304 0.000
B50-B64 Protozoal diseases
0.696 0.304 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.696 0.304 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.696 0.304 0.000
A75-A79 Rickettsioses
0.696 0.304 0.000
A70-A74 Other diseases caused by chlamydiae
0.696 0.304 0.000
A65-A69 Other spirochaetal diseases
0.696 0.304 0.000
A20-A28 Certain zoonotic bacterial diseases
0.696 0.304 0.000
A15-A19 Tuberculosis
0.696 0.304 0.000
B02 Zoster [herpes zoster]
0.696 0.304 0.000
R25.1 Tremor, unspecified
0.695 0.305 0.000
R52.2 Other chronic pain
0.695 0.305 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.693 0.307 0.000
S02.2 Fracture of nasal bones
0.693 0.307 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.693 0.307 0.000
J18.9 Pneumonia, unspecified
0.692 0.308 0.000
C64-C68 Malignant neoplasms of urinary tract
0.691 0.309 0.000
S50.9 Superficial injury of forearm, unspecified
0.690 0.310 0.000
C90.0 Multiple myeloma
0.690 0.310 0.000
F00 Dementia in Alzheimer's disease
0.690 0.310 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.688 0.312 0.000
B95-B98 Bacterial, viral and other infectious agents
0.688 0.312 0.000
Z35 Supervision of high-risk pregnancy
0.687 0.313 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.686 0.314 0.000
D50 Iron deficiency anaemia
0.686 0.314 0.000
N20.1 Calculus of ureter
0.686 0.314 0.000
N10 Acute tubulo-interstitial nephritis
0.686 0.314 0.000
F31 Bipolar affective disorder
0.686 0.314 0.000
R52.0 Acute pain
0.686 0.314 0.000
K73 Chronic hepatitis, not elsewhere classified
0.686 0.314 0.000
G51.0 Bell's palsy
0.685 0.315 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.685 0.315 0.000
R80 Isolated proteinuria
0.684 0.316 0.000
S02.8 Fractures of other skull and facial bones
0.684 0.316 0.000
Z44 Fitting and adjustment of external prosthetic device
0.684 0.316 0.000
R29.4 Clicking hip
0.684 0.316 0.000
R29.3 Abnormal posture
0.684 0.316 0.000
R29.2 Abnormal reflex
0.684 0.316 0.000
R29.1 Meningismus
0.684 0.316 0.000
R29.0 Tetany
0.684 0.316 0.000
S01.3 Open wound of ear
0.684 0.316 0.000
K70.0 Alcoholic fatty liver
0.684 0.316 0.000
D55-D59 Haemolytic anaemias
0.683 0.317 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.682 0.318 0.000
D69.5 Secondary thrombocytopenia
0.682 0.318 0.000
C54 Malignant neoplasm of corpus uteri
0.682 0.318 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.682 0.318 0.000
Q80-Q89 Other congenital malformations
0.682 0.318 0.000
Q35-Q37 Cleft lip and cleft palate
0.682 0.318 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.682 0.318 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.682 0.318 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.682 0.318 0.000
J70 Respiratory conditions due to other external agents
0.682 0.318 0.000
J68 Respiratory conditions due to inhalation of chemicals, gases, fumes and vapours
0.682 0.318 0.000
J67 Hypersensitivity pneumonitis due to organic dust
0.682 0.318 0.000
J66 Airway disease due to specific organic dust
0.682 0.318 0.000
J63 Pneumoconiosis due to other inorganic dusts
0.682 0.318 0.000
J62 Pneumoconiosis due to dust containing silica
0.682 0.318 0.000
J65 Pneumoconiosis associated with tuberculosis
0.682 0.318 0.000
J64 Unspecified pneumoconiosis
0.682 0.318 0.000
J60 Coalworker's pneumoconiosis
0.682 0.318 0.000
Z43 Attention to artificial openings
0.681 0.319 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.681 0.319 0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere
0.681 0.319 0.000
N15 Other renal tubulo-interstitial diseases
0.681 0.319 0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
0.681 0.319 0.000
N11 Chronic tubulo-interstitial nephritis
0.681 0.319 0.000
R94.3 Abnormal results of cardiovascular function studies
0.680 0.320 0.000
Z75 Problems related to medical facilities and other health care
0.680 0.320 0.000
C79.6 Secondary malignant neoplasm of ovary
0.678 0.322 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.678 0.322 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.678 0.322 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.678 0.322 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.678 0.322 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.678 0.322 0.000
G91.1 Obstructive hydrocephalus
0.678 0.322 0.000
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction
0.678 0.322 0.000
F02 Dementia in other diseases classified elsewhere
0.678 0.322 0.000
F09 Unspecified organic or symptomatic mental disorder
0.678 0.322 0.000
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances
0.678 0.322 0.000
R92 Abnormal findings on diagnostic imaging of breast
0.678 0.322 0.000
Y52 Agents primarily affecting the cardiovascular system
0.677 0.322 0.000
G90.2 Horner's syndrome
0.677 0.322 0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction
0.677 0.323 0.000
S02.5 Fracture of tooth
0.677 0.323 0.000
K75 Other inflammatory liver diseases
0.677 0.323 0.000
D75 Other diseases of blood and blood-forming organs
0.677 0.323 0.000
N76 Other inflammation of vagina and vulva
0.676 0.324 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.676 0.324 0.000
Z51.2 Other chemotherapy
0.675 0.325 0.000
R44.8 Other and unspecified symptoms and signs involving general sensations and perceptions
0.675 0.325 0.000
R44.2 Other hallucinations
0.675 0.325 0.000
H44 Disorders of globe
0.673 0.327 0.000
Z51.6 Desensitisation to allergens
0.673 0.327 0.000
R27 Other lack of coordination
0.672 0.328 0.000
K92 Other diseases of digestive system
0.672 0.328 0.000
D80-D89 Certain disorders involving the immune mechanism
0.672 0.328 0.000
N13.7 Vesicoureteral-reflux-associated uropathy
0.671 0.329 0.000
N13.6 Pyonephrosis
0.671 0.329 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.671 0.329 0.000
J12 Viral pneumonia, not elsewhere classified
0.671 0.329 0.000
J14 Pneumonia due to Haemophilus influenzae
0.671 0.329 0.000
J09 Influenza due to certain identified influenza virus
0.671 0.329 0.000
M47 Spondylosis
0.671 0.329 0.000
C53.9 Cervix uteri, unspecified
0.669 0.330 0.000
J00 Acute nasopharyngitis [common cold]
0.669 0.331 0.000
G83.4 Cauda equina syndrome
0.668 0.332 0.000
J03 Acute tonsillitis
0.668 0.332 0.000
H04.1 Other disorders of lachrymal gland
0.668 0.332 0.000
M65-M68 Disorders of synovium and tendon
0.667 0.333 0.000
H02.7 Other degenerative disorders of eyelid and periocular area
0.666 0.333 0.000
H02.2 Lagophthalmos
0.666 0.333 0.000
R26.2 Difficulty in walking, not elsewhere classified
0.666 0.334 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.666 0.334 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.666 0.334 0.000
A86 Unspecified viral encephalitis
0.665 0.335 0.000
Q60-Q64 Congenital malformations of the urinary system
0.665 0.335 0.000
R05 Cough
0.665 0.335 0.000
Z50.6 Orthoptic training
0.664 0.335 0.000
Z50.3 Drug rehabilitation
0.664 0.335 0.000
G99.2 Myelopathy in diseases classified elsewhere
0.664 0.335 0.000
Chapter XXII Codes for special purposes
0.664 0.336 0.000
Z73.9 Problem related to life-management difficulty, unspecified
0.664 0.336 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.664 0.336 0.000
C85.1 B-cell lymphoma, unspecified
0.664 0.336 0.000
Z50.2 Alcohol rehabilitation
0.663 0.337 0.000
Z34 Supervision of normal pregnancy
0.663 0.337 0.000
J94 Other pleural conditions
0.663 0.337 0.000
Z76 Persons encountering health services in other circumstances
0.662 0.337 0.000
Z70 Counselling related to sexual attitude, behaviour and orientation
0.662 0.337 0.000
S50.0 Contusion of elbow
0.662 0.338 0.000
J92 Pleural plaque
0.662 0.338 0.000
Q21 Congenital malformations of cardiac septa
0.661 0.339 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.661 0.339 0.000
C90.2 Plasmacytoma, extramedullary
0.661 0.339 0.000
C73 Malignant neoplasm of thyroid gland
0.661 0.339 0.000
N20.2 Calculus of kidney with calculus of ureter
0.660 0.339 0.000
B49 Unspecified mycosis
0.660 0.340 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.660 0.340 0.000
R41.2 Retrograde amnesia
0.659 0.341 0.000
R41.1 Anterograde amnesia
0.659 0.341 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.658 0.341 0.000
J30-J39 Other diseases of upper respiratory tract
0.657 0.343 0.000
S02.1 Fracture of base of skull
0.656 0.344 0.000
A87 Viral meningitis
0.656 0.344 0.000
O48 Prolonged pregnancy
0.656 0.344 0.000
Z30 Contraceptive management
0.656 0.344 0.000
N22 Calculus of urinary tract in diseases classified elsewhere
0.655 0.344 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.655 0.344 0.000
C95 Leukaemia of unspecified cell type
0.655 0.344 0.000
C94 Other leukaemias of specified cell type
0.655 0.344 0.000
C93 Monocytic leukaemia
0.655 0.344 0.000
C88 Malignant immunoproliferative diseases
0.655 0.344 0.000
C86 Other specified types of T/NK-cell lymphoma
0.655 0.344 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.655 0.344 0.000
H05.0 Acute inflammation of orbit
0.655 0.345 0.000
O85-O92 Complications predominantly related to the puerperium
0.655 0.345 0.000
J17.2 Pneumonia in mycoses
0.655 0.345 0.000
S59 Other and unspecified injuries of forearm
0.654 0.346 0.000
S58 Traumatic amputation of forearm
0.654 0.346 0.000
S57 Crushing injury of forearm
0.654 0.346 0.000
S56 Injury of muscle and tendon at forearm level
0.654 0.346 0.000
S55 Injury of blood vessels at forearm level
0.654 0.346 0.000
S54 Injury of nerves at forearm level
0.654 0.346 0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow
0.654 0.346 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.654 0.346 0.000
R49 Voice disturbances
0.654 0.346 0.000
O61 Failed induction of labour
0.654 0.346 0.000
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms
0.654 0.346 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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