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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs114520588
log Bayes Factor = 15.0452
Chromosome 5   position 102,609,139  (GRCh37) Explore rs114520588 on Ensembl!
Variant rs114520588 is part of Cluster X0192

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter X Diseases of the respiratory system
1.000 0.000 0.000
Chapter I Certain infectious and parasitic diseases
0.998 0.002 0.000
Chapter XIV Diseases of the genitourinary system
0.997 0.003 0.000
Chapter V Mental and behavioural disorders
0.994 0.006 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.991 0.009 0.000
J40-J47 Chronic lower respiratory diseases
0.989 0.011 0.000
B95-B98 Bacterial, viral and other infectious agents
0.988 0.012 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.987 0.013 0.000
Chapter XI Diseases of the digestive system
0.982 0.018 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.971 0.029 0.000
J44 Other chronic obstructive pulmonary disease
0.970 0.030 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.969 0.031 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.969 0.031 0.000
J30-J39 Other diseases of upper respiratory tract
0.960 0.040 0.000
A30-A49 Other bacterial diseases
0.957 0.043 0.000
K70-K77 Diseases of liver
0.955 0.045 0.000
M70-M79 Other soft tissue disorders
0.953 0.047 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.952 0.048 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.951 0.049 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.950 0.050 0.000
E70-E90 Metabolic disorders
0.942 0.058 0.000
K70 Alcoholic liver disease
0.939 0.061 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.937 0.063 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.932 0.068 0.000
A41 Other septicaemia
0.929 0.071 0.000
J09-J18 Influenza and pneumonia
0.927 0.073 0.000
N60-N64 Disorders of breast
0.927 0.073 0.000
N30-N39 Other diseases of urinary system
0.927 0.073 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.927 0.073 0.000
M79.6 Pain in limb
0.923 0.077 0.000
J32 Chronic sinusitis
0.922 0.078 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.920 0.080 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.919 0.081 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.917 0.083 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.914 0.086 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.913 0.087 0.000
M79.8 Other specified soft tissue disorders
0.912 0.088 0.000
Chapter II Neoplasms
0.909 0.091 0.000
N17-N19 Renal failure
0.908 0.092 0.000
M79.66 Pain in limb (Lower leg)
0.907 0.093 0.000
N35 Urethral stricture
0.903 0.097 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.899 0.101 0.000
J43 Emphysema
0.897 0.103 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.896 0.104 0.000
J20-J22 Other acute lower respiratory infections
0.894 0.106 0.000
K81 Cholecystitis
0.892 0.108 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.892 0.108 0.000
C15-C26 Malignant neoplasms of digestive organs
0.892 0.108 0.000
K70.9 Alcoholic liver disease, unspecified
0.890 0.110 0.000
N35.9 Urethral stricture, unspecified
0.886 0.114 0.000
F41 Other anxiety disorders
0.885 0.115 0.000
Chapter XXI Factors influencing health status and contact with health services
0.885 0.115 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.884 0.116 0.000
M15-M19 Arthrosis
0.875 0.125 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.873 0.127 0.000
T40.2 Other opioids
0.868 0.132 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.866 0.134 0.000
J32.0 Chronic maxillary sinusitis
0.861 0.139 0.000
C18 Malignant neoplasm of colon
0.861 0.139 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.860 0.140 0.000
A41.5 Septicaemia due to other Gram-negative organisms
0.858 0.142 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.857 0.143 0.000
N18 Chronic renal failure
0.856 0.144 0.000
Chapter XXII Codes for special purposes
0.853 0.147 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.853 0.147 0.000
S60-S69 Injuries to the wrist and hand
0.853 0.147 0.000
K81.0 Acute cholecystitis
0.852 0.148 0.000
E86 Volume depletion
0.850 0.150 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.847 0.153 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.845 0.155 0.000
F99-F99 Unspecified mental disorder
0.844 0.156 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.844 0.156 0.000
S40-S49 Injuries to the shoulder and upper arm
0.841 0.159 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.839 0.161 0.000
M79.86 Other specified soft tissue disorders (Lower leg)
0.838 0.162 0.000
T51 Toxic effect of alcohol
0.828 0.172 0.000
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters
0.827 0.173 0.000
Z04 Examination and observation for other reasons
0.826 0.174 0.000
Chapter VI Diseases of the nervous system
0.825 0.175 0.000
C18.7 Sigmoid colon
0.825 0.175 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.824 0.176 0.000
K80 Cholelithiasis
0.824 0.176 0.000
K65-K67 Diseases of peritoneum
0.823 0.177 0.000
N00-N08 Glomerular diseases
0.822 0.178 0.000
K70.3 Alcoholic cirrhosis of liver
0.822 0.178 0.000
N18.9 Chronic renal failure, unspecified
0.821 0.179 0.000
K90-K93 Other diseases of the digestive system
0.819 0.181 0.000
J18 Pneumonia, organism unspecified
0.819 0.181 0.000
J22 Unspecified acute lower respiratory infection
0.817 0.183 0.000
F41.9 Anxiety disorder, unspecified
0.816 0.184 0.000
O36 Maternal care for other known or suspected foetal problems
0.814 0.186 0.000
Z08 Follow-up examination after treatment for malignant neoplasm
0.814 0.186 0.000
R26 Abnormalities of gait and mobility
0.814 0.186 0.000
M79.87 Other specified soft tissue disorders (Ankle and foot)
0.813 0.187 0.000
Z04.8 Examination and observation for other specified reasons
0.812 0.188 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.812 0.188 0.000
F30-F39 Mood [affective] disorders
0.810 0.190 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.810 0.190 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.809 0.191 0.000
N99-N99 Other disorders of the genitourinary system
0.809 0.191 0.000
N86 Erosion and ectropion of cervix uteri
0.809 0.191 0.000
R05 Cough
0.808 0.192 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.808 0.192 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.806 0.194 0.000
D00-D09 In situ neoplasms
0.806 0.194 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.805 0.195 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.804 0.196 0.000
K85 Acute pancreatitis
0.803 0.197 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.803 0.197 0.000
J46 Status asthmaticus
0.801 0.199 0.000
N85 Other noninflammatory disorders of uterus, except cervix
0.800 0.200 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.799 0.201 0.000
A41.9 Septicaemia, unspecified
0.799 0.201 0.000
K70.4 Alcoholic hepatic failure
0.799 0.201 0.000
N32 Other disorders of bladder
0.798 0.201 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.796 0.203 0.000
M91-M94 Chondropathies
0.796 0.204 0.000
M40-M43 Deforming dorsopathies
0.796 0.204 0.000
B35-B49 Mycoses
0.796 0.204 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.795 0.205 0.000
E40-E46 Malnutrition
0.794 0.206 0.000
J43.9 Emphysema, unspecified
0.793 0.207 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.792 0.208 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.790 0.210 0.000
J18.1 Lobar pneumonia, unspecified
0.789 0.211 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.788 0.212 0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters
0.787 0.213 0.000
M79.67 Pain in limb (Ankle and foot)
0.787 0.213 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.787 0.213 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.786 0.214 0.000
N80 Endometriosis
0.784 0.216 0.000
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters
0.783 0.217 0.000
N63 Unspecified lump in breast
0.782 0.218 0.000
Z08.9 Follow-up examination after unspecified treatment for malignant neoplasm
0.782 0.218 0.000
K80.2 Calculus of gallbladder without cholecystitis
0.781 0.219 0.000
N64 Other disorders of breast
0.781 0.219 0.000
R00 Abnormalities of heart beat
0.780 0.220 0.000
E20-E35 Disorders of other endocrine glands
0.780 0.220 0.000
A41.0 Septicaemia due to Staphylococcus aureus
0.777 0.223 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.777 0.223 0.000
T51.0 Ethanol
0.776 0.224 0.000
J42 Unspecified chronic bronchitis
0.776 0.224 0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.774 0.226 0.000
R45 Symptoms and signs involving emotional state
0.773 0.227 0.000
R41.0 Disorientation, unspecified
0.770 0.230 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.770 0.230 0.000
J00-J06 Acute upper respiratory infections
0.769 0.231 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.769 0.231 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.768 0.232 0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts
0.766 0.234 0.000
M17 Gonarthrosis [arthrosis of knee]
0.766 0.234 0.000
J95-J99 Other diseases of the respiratory system
0.765 0.234 0.000
F60-F69 Disorders of adult personality and behaviour
0.764 0.236 0.000
M18 Arthrosis of first carpometacarpal joint
0.763 0.237 0.000
M79.2 Neuralgia and neuritis, unspecified
0.758 0.242 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.756 0.244 0.000
E88 Other metabolic disorders
0.755 0.245 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.755 0.245 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.754 0.246 0.000
N25-N29 Other disorders of kidney and ureter
0.754 0.246 0.000
J39 Other diseases of upper respiratory tract
0.754 0.246 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.753 0.247 0.000
K81.9 Cholecystitis, unspecified
0.752 0.248 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.752 0.248 0.000
F43 Reaction to severe stress, and adjustment disorders
0.750 0.250 0.000
J60-J70 Lung diseases due to external agents
0.749 0.251 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.748 0.252 0.000
R26.8 Other and unspecified abnormalities of gait and mobility
0.748 0.252 0.000
M79.69 Pain in limb (Site unspecified)
0.747 0.253 0.000
M86-M90 Other osteopathies
0.746 0.253 0.000
M71 Other bursopathies
0.746 0.254 0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters
0.742 0.258 0.000
E10-E14 Diabetes mellitus
0.741 0.259 0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters
0.740 0.260 0.000
S50-S59 Injuries to the elbow and forearm
0.740 0.260 0.000
N32.8 Other specified disorders of bladder
0.737 0.263 0.000
F99 Mental disorder, not otherwise specified
0.737 0.263 0.000
A00-A09 Intestinal infectious diseases
0.737 0.263 0.000
J43.2 Centrilobular emphysema
0.737 0.263 0.000
K75 Other inflammatory liver diseases
0.736 0.264 0.000
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters
0.736 0.264 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.736 0.264 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.734 0.266 0.000
R00.0 Tachycardia, unspecified
0.734 0.266 0.000
N61 Inflammatory disorders of breast
0.734 0.266 0.000
C20 Malignant neoplasm of rectum
0.733 0.267 0.000
J30 Vasomotor and allergic rhinitis
0.732 0.268 0.000
N90 Other noninflammatory disorders of vulva and perineum
0.731 0.269 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.731 0.269 0.000
E50-E64 Other nutritional deficiencies
0.731 0.269 0.000
J32.9 Chronic sinusitis, unspecified
0.729 0.271 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.728 0.271 0.000
C64-C68 Malignant neoplasms of urinary tract
0.728 0.272 0.000
K72 Hepatic failure, not elsewhere classified
0.727 0.273 0.000
J90-J94 Other diseases of pleura
0.727 0.273 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.725 0.275 0.000
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis
0.724 0.276 0.000
J32.2 Chronic ethmoidal sinusitis
0.723 0.276 0.000
T42.4 Benzodiazepines
0.723 0.277 0.000
M17.1 Other primary gonarthrosis
0.723 0.277 0.000
J36 Peritonsillar abscess
0.722 0.278 0.000
E87.5 Hyperkalaemia
0.722 0.278 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.722 0.278 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.720 0.280 0.000
N18.4 Chronic kidney disease, stage 4
0.720 0.280 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.718 0.282 0.000
O40 Polyhydramnios
0.717 0.283 0.000
F42 Obsessive-compulsive disorder
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T79-T79 Certain early complications of trauma
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
S10-S19 Injuries to the neck
0.717 0.283 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.716 0.284 0.000
B99-B99 Other infectious diseases
0.716 0.284 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.716 0.284 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.716 0.284 0.000
B65-B83 Helminthiases
0.716 0.284 0.000
B50-B64 Protozoal diseases
0.716 0.284 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.716 0.284 0.000
B15-B19 Viral hepatitis
0.716 0.284 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.716 0.284 0.000
A80-A89 Viral infections of the central nervous system
0.716 0.284 0.000
A75-A79 Rickettsioses
0.716 0.284 0.000
A70-A74 Other diseases caused by chlamydiae
0.716 0.284 0.000
A65-A69 Other spirochaetal diseases
0.716 0.284 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.716 0.284 0.000
A20-A28 Certain zoonotic bacterial diseases
0.716 0.284 0.000
A15-A19 Tuberculosis
0.716 0.284 0.000
J32.8 Other chronic sinusitis
0.716 0.284 0.000
N85.0 Endometrial glandular hyperplasia
0.715 0.284 0.000
T39.0 Salicylates
0.715 0.285 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.715 0.285 0.000
B25-B34 Other viral diseases
0.714 0.286 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.712 0.287 0.000
F80-F89 Disorders of psychological development
0.712 0.287 0.000
F70-F79 Mental retardation
0.712 0.287 0.000
N40-N51 Diseases of male genital organs
0.713 0.287 0.000
S90-S99 Injuries to the ankle and foot
0.712 0.288 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.712 0.288 0.000
F31 Bipolar affective disorder
0.711 0.289 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.711 0.289 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.711 0.289 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.711 0.289 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.711 0.289 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.711 0.289 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.711 0.289 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.711 0.289 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.711 0.289 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.711 0.289 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.711 0.289 0.000
T36 Poisoning by systemic antibiotics
0.711 0.289 0.000
R02 Gangrene, not elsewhere classified
0.711 0.289 0.000
J41 Simple and mucopurulent chronic bronchitis
0.709 0.291 0.000
T39.1 4-Aminophenol derivatives
0.709 0.291 0.000
T87 Complications peculiar to reattachment and amputation
0.707 0.292 0.000
T86 Failure and rejection of transplanted organs and tissues
0.707 0.292 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.706 0.294 0.000
S61 Open wound of wrist and hand
0.705 0.295 0.000
J35 Chronic diseases of tonsils and adenoids
0.704 0.295 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.704 0.296 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.702 0.298 0.000
F10.1 Harmful use
0.701 0.299 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.699 0.301 0.000
C18.6 Descending colon
0.698 0.302 0.000
R45.8 Other symptoms and signs involving emotional state
0.698 0.302 0.000
O36.5 Maternal care for poor foetal growth
0.698 0.302 0.000
F41.0 Panic disorder [episodic paroxysmal anxiety]
0.698 0.302 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.697 0.303 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.697 0.303 0.000
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters
0.696 0.304 0.000
B95.0 Streptococcus, group A, as the cause of diseases classified to other chapters
0.696 0.304 0.000
K08 Other disorders of teeth and supporting structures
0.695 0.305 0.000
N60 Benign mammary dysplasia
0.695 0.305 0.000
T84.2 Mechanical complication of internal fixation device of other bones
0.694 0.306 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.694 0.306 0.000
M60-M63 Disorders of muscles
0.694 0.306 0.000
M00-M03 Infectious arthropathies
0.694 0.306 0.000
S42 Fracture of shoulder and upper arm
0.694 0.306 0.000
O85-O92 Complications predominantly related to the puerperium
0.694 0.306 0.000
O42 Premature rupture of membranes
0.693 0.306 0.000
D03 Melanoma in situ
0.693 0.307 0.000
K85.1 Biliary acute pancreatitis
0.693 0.307 0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]
0.692 0.308 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.692 0.308 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.691 0.309 0.000
S70-S79 Injuries to the hip and thigh
0.691 0.309 0.000
M79.7 Fibromyalgia
0.690 0.310 0.000
F45 Somatoform disorders
0.690 0.310 0.000
R23 Other skin changes
0.690 0.310 0.000
J37 Chronic laryngitis and laryngotracheitis
0.688 0.311 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.688 0.312 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.688 0.312 0.000
Z08.8 Follow-up examination after other treatment for malignant neoplasm
0.688 0.312 0.000
M79.0 Rheumatism, unspecified
0.688 0.312 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.687 0.312 0.000
Z04.1 Examination and observation following transport accident
0.687 0.313 0.000
K90 Intestinal malabsorption
0.687 0.313 0.000
A48 Other bacterial diseases, not elsewhere classified
0.686 0.314 0.000
A44 Bartonellosis
0.686 0.314 0.000
A43 Nocardiosis
0.686 0.314 0.000
A42 Actinomycosis
0.686 0.314 0.000
A40 Streptococcal septicaemia
0.686 0.314 0.000
A39 Meningococcal infection
0.686 0.314 0.000
A37 Whooping cough
0.686 0.314 0.000
A36 Diphtheria
0.686 0.314 0.000
A32 Listeriosis
0.686 0.314 0.000
A31 Infection due to other mycobacteria
0.686 0.314 0.000
A30 Leprosy [Hansen's disease]
0.686 0.314 0.000
A46 Erysipelas
0.686 0.314 0.000
A38 Scarlet fever
0.686 0.314 0.000
A35 Other tetanus
0.686 0.314 0.000
A34 Obstetrical tetanus
0.686 0.314 0.000
A33 Tetanus neonatorum
0.686 0.314 0.000
O00-O08 Pregnancy with abortive outcome
0.686 0.314 0.000
Z11 Special screening examination for infectious and parasitic diseases
0.686 0.314 0.000
F41.2 Mixed anxiety and depressive disorder
0.686 0.314 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.685 0.315 0.000
K77 Liver disorders in diseases classified elsewhere
0.684 0.316 0.000
K73 Chronic hepatitis, not elsewhere classified
0.684 0.316 0.000
K71 Toxic liver disease
0.684 0.316 0.000
R26.2 Difficulty in walking, not elsewhere classified
0.684 0.316 0.000
M76 Enthesopathies of lower limb, excluding foot
0.683 0.317 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.683 0.317 0.000
N85.2 Hypertrophy of uterus
0.683 0.317 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.683 0.317 0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.683 0.317 0.000
E10 Insulin-dependent diabetes mellitus
0.682 0.318 0.000
R04 Haemorrhage from respiratory passages
0.682 0.318 0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft
0.681 0.318 0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis
0.681 0.318 0.000
T82.4 Mechanical complication of vascular dialysis catheter
0.681 0.318 0.000
T82.3 Mechanical complication of other vascular grafts
0.681 0.318 0.000
T82.0 Mechanical complication of heart valve prosthesis
0.681 0.318 0.000
M79.9 Soft tissue disorder, unspecified
0.681 0.319 0.000
M79.5 Residual foreign body in soft tissue
0.681 0.319 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.681 0.319 0.000
M79.3 Panniculitis, unspecified
0.681 0.319 0.000
M79.1 Myalgia
0.681 0.319 0.000
N62 Hypertrophy of breast
0.680 0.320 0.000
N36 Other disorders of urethra
0.678 0.321 0.000
A49 Bacterial infection of unspecified site
0.678 0.322 0.000
K35-K38 Diseases of appendix
0.677 0.323 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.676 0.323 0.000
T82.1 Mechanical complication of cardiac electronic device
0.676 0.324 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.676 0.324 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.676 0.324 0.000
E85 Amyloidosis
0.675 0.325 0.000
E84 Cystic fibrosis
0.675 0.325 0.000
E79 Disorders of purine and pyrimidine metabolism
0.675 0.325 0.000
E77 Disorders of glycoprotein metabolism
0.675 0.325 0.000
E76 Disorders of glycosaminoglycan metabolism
0.675 0.325 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.675 0.325 0.000
E74 Other disorders of carbohydrate metabolism
0.675 0.325 0.000
E73 Lactose intolerance
0.675 0.325 0.000
E72 Other disorders of amino-acid metabolism
0.675 0.325 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.675 0.325 0.000
E70 Disorders of aromatic amino-acid metabolism
0.675 0.325 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.675 0.325 0.000
T66-T78 Other and unspecified effects of external causes
0.675 0.325 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.675 0.325 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.674 0.326 0.000
J00 Acute nasopharyngitis [common cold]
0.674 0.326 0.000
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified
0.674 0.326 0.000
T18 Foreign body in alimentary tract
0.674 0.326 0.000
K70.2 Alcoholic fibrosis and sclerosis of liver
0.673 0.327 0.000
K70.1 Alcoholic hepatitis
0.673 0.327 0.000
K70.0 Alcoholic fatty liver
0.673 0.327 0.000
M93 Other osteochondropathies
0.673 0.327 0.000
T88.7 Unspecified adverse effect of drug or medicament
0.673 0.327 0.000
C15 Malignant neoplasm of oesophagus
0.672 0.327 0.000
N32.9 Bladder disorder, unspecified
0.672 0.328 0.000
F48 Other neurotic disorders
0.672 0.328 0.000
F44 Dissociative [conversion] disorders
0.672 0.328 0.000
J47 Bronchiectasis
0.672 0.328 0.000
G30-G32 Other degenerative diseases of the nervous system
0.671 0.329 0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.671 0.329 0.000
L08 Other local infections of skin and subcutaneous tissue
0.670 0.330 0.000
K65 Peritonitis
0.670 0.330 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.669 0.331 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.669 0.331 0.000
O48 Prolonged pregnancy
0.669 0.331 0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts
0.669 0.331 0.000
E46 Unspecified protein-energy malnutrition
0.669 0.331 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.668 0.332 0.000
K86 Other diseases of pancreas
0.668 0.332 0.000
M43 Other deforming dorsopathies
0.666 0.333 0.000
A41.8 Other specified septicaemia
0.666 0.334 0.000
A41.4 Septicaemia due to anaerobes
0.666 0.334 0.000
A41.3 Septicaemia due to Haemophilus influenzae
0.666 0.334 0.000
A41.2 Septicaemia due to unspecified staphylococcus
0.666 0.334 0.000
A41.1 Septicaemia due to other specified staphylococcus
0.666 0.334 0.000
J17 Pneumonia in diseases classified elsewhere
0.665 0.335 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.665 0.335 0.000
J12 Viral pneumonia, not elsewhere classified
0.665 0.335 0.000
J11 Influenza, virus not identified
0.665 0.335 0.000
J10 Influenza due to identified influenza virus
0.665 0.335 0.000
J14 Pneumonia due to Haemophilus influenzae
0.665 0.335 0.000
J09 Influenza due to certain identified influenza virus
0.665 0.335 0.000
K82 Other diseases of gallbladder
0.665 0.335 0.000
N37 Urethral disorders in diseases classified elsewhere
0.665 0.335 0.000
N34 Urethritis and urethral syndrome
0.665 0.335 0.000
N33 Bladder disorders in diseases classified elsewhere
0.665 0.335 0.000
Chapter XX External causes of morbidity and mortality
0.665 0.335 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.664 0.335 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.664 0.335 0.000
M79.89 Other specified soft tissue disorders (Site unspecified)
0.664 0.336 0.000
M18.9 Arthrosis of first carpometacarpal joint, unspecified
0.662 0.338 0.000
N18.0 End-stage renal disease
0.662 0.338 0.000
M79.68 Pain in limb (Other)
0.661 0.338 0.000
M79.64 Pain in limb (Hand)
0.661 0.338 0.000
M79.63 Pain in limb (Forearm)
0.661 0.338 0.000
M79.61 Pain in limb (Shoulder region)
0.661 0.338 0.000
J32.4 Chronic pansinusitis
0.661 0.339 0.000
J32.3 Chronic sphenoidal sinusitis
0.661 0.339 0.000
J32.1 Chronic frontal sinusitis
0.661 0.339 0.000
O32.1 Maternal care for breech presentation
0.661 0.339 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.661 0.339 0.000
O36.8 Maternal care for other specified foetal problems
0.660 0.340 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.660 0.340 0.000
T39.4 Antirheumatics, not elsewhere classified
0.660 0.340 0.000
T39.2 Pyrazolone derivatives
0.660 0.340 0.000
N88 Other noninflammatory disorders of cervix uteri
0.660 0.340 0.000
E65-E68 Obesity and other hyperalimentation
0.660 0.340 0.000
F41.1 Generalised anxiety disorder
0.659 0.340 0.000
N64.8 Other specified disorders of breast
0.659 0.341 0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]
0.659 0.341 0.000
T40.8 Lysergide [LSD]
0.659 0.341 0.000
T40.7 Cannabis (derivatives)
0.659 0.341 0.000
T40.6 Other and unspecified narcotics
0.659 0.341 0.000
T40.5 Cocaine
0.659 0.341 0.000
T40.4 Other synthetic narcotics
0.659 0.341 0.000
T40.3 Methadone
0.659 0.341 0.000
T40.1 Heroin
0.659 0.341 0.000
T40.0 Opium
0.659 0.341 0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.659 0.341 0.000
M77 Other enthesopathies
0.659 0.341 0.000
N80.1 Endometriosis of ovary
0.658 0.342 0.000
N04 Nephrotic syndrome
0.658 0.342 0.000
D06 Carcinoma in situ of cervix uteri
0.656 0.344 0.000
A09 Diarrhoea and gastro-enteritis of presumed infectious origin
0.655 0.345 0.000
M79.88 Other specified soft tissue disorders (Other)
0.654 0.346 0.000
M79.85 Other specified soft tissue disorders (Pelvic region and thigh)
0.654 0.346 0.000
M79.84 Other specified soft tissue disorders (Hand)
0.654 0.346 0.000
M79.83 Other specified soft tissue disorders (Forearm)
0.654 0.346 0.000
M79.82 Other specified soft tissue disorders (Upper arm)
0.654 0.346 0.000
M79.81 Other specified soft tissue disorders (Shoulder region)
0.654 0.346 0.000
M79.80 Other specified soft tissue disorders (Multiple sites)
0.654 0.346 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.653 0.347 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.652 0.348 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.652 0.348 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.652 0.348 0.000
M80-M85 Disorders of bone density and structure
0.651 0.349 0.000
Chapter IX Diseases of the circulatory system
0.651 0.349 0.000
L50-L54 Urticaria and erythema
0.651 0.349 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.651 0.349 0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts
0.651 0.349 0.000
E78.5 Hyperlipidaemia, unspecified
0.651 0.349 0.000
Z60 Problems related to social environment
0.651 0.349 0.000
N17 Acute renal failure
0.651 0.349 0.000
K66 Other disorders of peritoneum
0.650 0.350 0.000
N85.1 Endometrial adenomatous hyperplasia
0.650 0.350 0.000
B37 Candidiasis
0.650 0.350 0.000
N80.2 Endometriosis of Fallopian tube
0.650 0.350 0.000
R47-R49 Symptoms and signs involving speech and voice
0.649 0.351 0.000
S62 Fracture at wrist and hand level
0.649 0.351 0.000
L05 Pilonidal cyst
0.648 0.352 0.000
K50-K52 Noninfective enteritis and colitis
0.648 0.352 0.000
N35.8 Other urethral stricture
0.647 0.353 0.000
N35.1 Postinfective urethral stricture, not elsewhere classified
0.647 0.353 0.000
N35.0 Posttraumatic urethral stricture
0.647 0.353 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.647 0.353 0.000
N97 Female infertility
0.647 0.353 0.000
E80.4 Gilbert's syndrome
0.647 0.353 0.000
N05 Unspecified nephritic syndrome
0.647 0.353 0.000
S32 Fracture of lumbar spine and pelvis
0.646 0.354 0.000
O32.5 Maternal care for multiple gestation with malpresentation of one foetus or more
0.646 0.354 0.000
E87.3 Alkalosis
0.646 0.354 0.000
T65 Toxic effect of other and unspecified substances
0.645 0.355 0.000
T63 Toxic effect of contact with venomous animals
0.645 0.355 0.000
T62 Toxic effect of other noxious substances eaten as food
0.645 0.355 0.000
T61 Toxic effect of noxious substances eaten as seafood
0.645 0.355 0.000
T60 Toxic effect of pesticides
0.645 0.355 0.000
T59 Toxic effect of other gases, fumes and vapours
0.645 0.355 0.000
T57 Toxic effect of other inorganic substances
0.645 0.355 0.000
T56 Toxic effect of metals
0.645 0.355 0.000
T54 Toxic effect of corrosive substances
0.645 0.355 0.000
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone
0.645 0.355 0.000
T52 Toxic effect of organic solvents
0.645 0.355 0.000
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants
0.645 0.355 0.000
T58 Toxic effect of carbon monoxide
0.645 0.355 0.000
T55 Toxic effect of soaps and detergents
0.645 0.355 0.000
Z57 Occupational exposure to risk-factors
0.644 0.355 0.000
N80.8 Other endometriosis
0.643 0.356 0.000
C18.9 Colon, unspecified
0.643 0.356 0.000
J43.8 Other emphysema
0.643 0.357 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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