TreeWAS – Variant ID: rs114733011

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E03.9 Hypothyroidism, unspecified	1.000	0.000	0.000
K51.9 Ulcerative colitis, unspecified	1.000	0.000	0.000
K50-K52 Noninfective enteritis and colitis	1.000	0.000	0.000
Chapter XI Diseases of the digestive system	1.000	0.000	0.000
# Top node	1.000	0.000	0.000
K51 Ulcerative colitis	1.000	0.000	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	1.000	0.000	0.000
K55-K64 Other diseases of intestines	1.000	0.000	0.000
E00-E07 Disorders of thyroid gland	1.000	0.000	0.000
E03 Other hypothyroidism	1.000	0.000	0.000
Chapter X Diseases of the respiratory system	1.000	0.000	0.000
K50 Crohn's disease [regional enteritis]	1.000	0.000	0.000
Z93.2 Ileostomy status	0.999	0.001	0.000
Chapter XIV Diseases of the genitourinary system	0.999	0.001	0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	0.999	0.001	0.000
R30-R39 Symptoms and signs involving the urinary system	0.999	0.001	0.000
Chapter VIII Diseases of the ear and mastoid process	0.999	0.001	0.000
R31 Unspecified haematuria	0.998	0.002	0.000
K20-K31 Diseases of oesophagus, stomach and duodenum	0.997	0.003	0.000
J30-J39 Other diseases of upper respiratory tract	0.997	0.003	0.000
H65-H75 Diseases of middle ear and mastoid	0.995	0.005	0.000
E70-E90 Metabolic disorders	0.994	0.006	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.994	0.006	0.000
K50.9 Crohn's disease, unspecified	0.993	0.007	0.000
K90.0 Coeliac disease	0.000	0.007	0.993
K62 Other diseases of anus and rectum	0.993	0.007	0.000
J20-J22 Other acute lower respiratory infections	0.992	0.008	0.000
R33 Retention of urine	0.991	0.009	0.000
K62.8 Other specified diseases of anus and rectum	0.991	0.009	0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.991	0.009	0.000
K30 Dyspepsia	0.989	0.011	0.000
K52 Other non-infective gastro-enteritis and colitis	0.988	0.012	0.000
J22 Unspecified acute lower respiratory infection	0.986	0.014	0.000
K60 Fissure and fistula of anal and rectal regions	0.986	0.014	0.000
K20 Oesophagitis	0.982	0.018	0.000
N20-N23 Urolithiasis	0.982	0.018	0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis	0.980	0.020	0.000
E78.0 Pure hypercholesterolaemia	0.979	0.021	0.000
K61 Abscess of anal and rectal regions	0.978	0.022	0.000
R05 Cough	0.978	0.022	0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems	0.977	0.023	0.000
N20 Calculus of kidney and ureter	0.974	0.026	0.000
K50.1 Crohn's disease of large intestine	0.973	0.027	0.000
K52.9 Non-infective gastro-enteritis and colitis, unspecified	0.966	0.034	0.000
K60.3 Anal fistula	0.965	0.035	0.000
N99-N99 Other disorders of the genitourinary system	0.964	0.036	0.000
K63 Other diseases of intestine	0.964	0.036	0.000
J31.0 Chronic rhinitis	0.963	0.037	0.000
N20.0 Calculus of kidney	0.963	0.037	0.000
J32 Chronic sinusitis	0.962	0.038	0.000
K61.0 Anal abscess	0.958	0.042	0.000
N60-N64 Disorders of breast	0.945	0.055	0.000
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified	0.940	0.060	0.000
E78.5 Hyperlipidaemia, unspecified	0.939	0.061	0.000
J34 Other disorders of nose and nasal sinuses	0.936	0.064	0.000
K63.8 Other specified diseases of intestine	0.935	0.065	0.000
H72 Perforation of tympanic membrane	0.935	0.065	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.934	0.066	0.000
H60-H62 Diseases of external ear	0.933	0.067	0.000
J32.9 Chronic sinusitis, unspecified	0.925	0.075	0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws	0.924	0.076	0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems	0.909	0.091	0.000
H71 Cholesteatoma of middle ear	0.907	0.093	0.000
E06 Thyroiditis	0.907	0.093	0.000
N64 Other disorders of breast	0.905	0.095	0.000
K62.1 Rectal polyp	0.903	0.097	0.000
Chapter VII Diseases of the eye and adnexa	0.902	0.098	0.000
N10-N16 Renal tubulo-interstitial diseases	0.900	0.100	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.900	0.100	0.000
K22 Other diseases of oesophagus	0.895	0.105	0.000
N99.8 Other postprocedural disorders of genito-urinary system	0.894	0.106	0.000
K52.1 Toxic gastro-enteritis and colitis	0.893	0.107	0.000
K51.4 Pseudopolyposis of colon	0.892	0.108	0.000
S00-S09 Injuries to the head	0.887	0.113	0.000
Chapter VI Diseases of the nervous system	0.887	0.113	0.000
N40-N51 Diseases of male genital organs	0.885	0.115	0.000
K59 Other functional intestinal disorders	0.884	0.116	0.000
K90-K93 Other diseases of the digestive system	0.837	0.116	0.047
J40-J47 Chronic lower respiratory diseases	0.883	0.117	0.000
H61 Other disorders of external ear	0.881	0.119	0.000
S40-S49 Injuries to the shoulder and upper arm	0.878	0.122	0.000
H65 Nonsuppurative otitis media	0.874	0.126	0.000
K12 Stomatitis and related lesions	0.873	0.127	0.000
Chapter II Neoplasms	0.873	0.127	0.000
Chapter V Mental and behavioural disorders	0.873	0.127	0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.866	0.134	0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems	0.864	0.136	0.000
J60-J70 Lung diseases due to external agents	0.862	0.138	0.000
K22.7 Barrett's oesophagus	0.860	0.140	0.000
C43-C44 Melanoma and other malignant neoplasms of skin	0.859	0.141	0.000
H73 Other disorders of tympanic membrane	0.854	0.146	0.000
E87 Other disorders of fluid, electrolyte and acid-base balance	0.853	0.147	0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.852	0.148	0.000
N50 Other disorders of male genital organs	0.849	0.151	0.000
N61 Inflammatory disorders of breast	0.847	0.153	0.000
K62.6 Ulcer of anus and rectum	0.847	0.153	0.000
F30-F39 Mood [affective] disorders	0.847	0.153	0.000
K50.0 Crohn's disease of small intestine	0.846	0.154	0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.845	0.155	0.000
K60.2 Anal fissure, unspecified	0.844	0.156	0.000
C44 Other malignant neoplasms of skin	0.843	0.157	0.000
S02 Fracture of skull and facial bones	0.842	0.158	0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified	0.842	0.158	0.000
T79-T79 Certain early complications of trauma	0.842	0.158	0.000
Chapter IX Diseases of the circulatory system	0.841	0.159	0.000
H72.9 Perforation of tympanic membrane, unspecified	0.841	0.159	0.000
E06.3 Autoimmune thyroiditis	0.840	0.160	0.000
J34.3 Hypertrophy of nasal turbinates	0.839	0.161	0.000
N64.9 Disorder of breast, unspecified	0.834	0.166	0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified	0.810	0.168	0.022
H74 Other disorders of middle ear and mastoid	0.830	0.170	0.000
J47 Bronchiectasis	0.828	0.172	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.823	0.177	0.000
H90-H95 Other disorders of ear	0.821	0.179	0.000
H61.2 Impacted cerumen	0.818	0.182	0.000
T66-T78 Other and unspecified effects of external causes	0.816	0.184	0.000
Z93 Artificial opening status	0.814	0.186	0.000
C44.3 Skin of other and unspecified parts of face	0.813	0.187	0.000
S20-S29 Injuries to the thorax	0.813	0.187	0.000
K27 Peptic ulcer, site unspecified	0.812	0.188	0.000
H72.0 Central perforation of tympanic membrane	0.811	0.189	0.000
K51.8 Other ulcerative colitis	0.810	0.190	0.000
N20.2 Calculus of kidney with calculus of ureter	0.809	0.191	0.000
R25 Abnormal involuntary movements	0.807	0.193	0.000
K12.1 Other forms of stomatitis	0.807	0.193	0.000
N50.1 Vascular disorders of male genital organs	0.806	0.194	0.000
N30-N39 Other diseases of urinary system	0.806	0.194	0.000
K51.2 Ulcerative (chronic) proctitis	0.806	0.194	0.000
R04 Haemorrhage from respiratory passages	0.805	0.195	0.000
H53-H54 Visual disturbances and blindness	0.803	0.197	0.000
T15-T19 Effects of foreign body entering through natural orifice	0.802	0.198	0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic	0.802	0.198	0.000
G50-G59 Nerve, nerve root and plexus disorders	0.801	0.199	0.000
I05-I09 Chronic rheumatic heart diseases	0.800	0.200	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.799	0.201	0.000
H65.2 Chronic serous otitis media	0.794	0.206	0.000
F33 Recurrent depressive disorder	0.794	0.206	0.000
E07 Other disorders of thyroid	0.793	0.207	0.000
N99.3 Prolapse of vaginal vault after hysterectomy	0.792	0.208	0.000
I20-I25 Ischaemic heart diseases	0.790	0.210	0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.788	0.212	0.000
J35 Chronic diseases of tonsils and adenoids	0.787	0.213	0.000
K62.2 Anal prolapse	0.787	0.213	0.000
N70-N77 Inflammatory diseases of female pelvic organs	0.786	0.214	0.000
E87.2 Acidosis	0.784	0.216	0.000
N64.8 Other specified disorders of breast	0.784	0.216	0.000
K62.7 Radiation proctitis	0.783	0.217	0.000
K91.4 Colostomy and enterostomy malfunction	0.778	0.217	0.005
E50-E64 Other nutritional deficiencies	0.781	0.219	0.000
R26 Abnormalities of gait and mobility	0.780	0.220	0.000
K90 Intestinal malabsorption	0.399	0.221	0.380
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.779	0.221	0.000
G90-G99 Other disorders of the nervous system	0.779	0.221	0.000
C44.7 Skin of lower limb, including hip	0.778	0.222	0.000
N99.0 Postprocedural renal failure	0.777	0.223	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.775	0.225	0.000
K63.5 Polyp of colon	0.775	0.225	0.000
J69 Pneumonitis due to solids and liquids	0.774	0.226	0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.774	0.226	0.000
K51.5 Mucosal proctocolitis	0.773	0.227	0.000
I08 Multiple valve diseases	0.773	0.227	0.000
S10-S19 Injuries to the neck	0.773	0.227	0.000
J34.2 Deviated nasal septum	0.772	0.228	0.000
K40-K46 Hernia	0.770	0.230	0.000
J31.2 Chronic pharyngitis	0.770	0.230	0.000
K61.3 Ischiorectal abscess	0.769	0.231	0.000
J40 Bronchitis, not specified as acute or chronic	0.767	0.233	0.000
R34 Anuria and oliguria	0.767	0.233	0.000
Q50-Q56 Congenital malformations of genital organs	0.764	0.236	0.000
E40-E46 Malnutrition	0.763	0.237	0.000
K59.0 Constipation	0.763	0.237	0.000
E88 Other metabolic disorders	0.763	0.237	0.000
J32.8 Other chronic sinusitis	0.762	0.238	0.000
K51.3 Ulcerative (chronic) rectosigmoiditis	0.760	0.240	0.000
F30 Manic episode	0.758	0.242	0.000
N30 Cystitis	0.758	0.242	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.757	0.243	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.756	0.244	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.755	0.245	0.000
K50.8 Other Crohn's disease	0.754	0.246	0.000
H55-H59 Other disorders of eye and adnexa	0.753	0.247	0.000
H73.8 Other specified disorders of tympanic membrane	0.753	0.247	0.000
K10 Other diseases of jaws	0.752	0.247	0.000
K52.3 Indeterminate colitis	0.752	0.248	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.751	0.249	0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis	0.751	0.249	0.000
S02.2 Fracture of nasal bones	0.750	0.250	0.000
K63.0 Abscess of intestine	0.749	0.251	0.000
C51-C58 Malignant neoplasms of female genital organs	0.749	0.251	0.000
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified	0.741	0.253	0.007
C83 Diffuse non-Hodgkin's lymphoma	0.747	0.253	0.000
J34.8 Other specified disorders of nose and nasal sinuses	0.746	0.254	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.745	0.254	0.000
T42.4 Benzodiazepines	0.745	0.255	0.000
G35-G37 Demyelinating diseases of the central nervous system	0.745	0.255	0.000
E86 Volume depletion	0.744	0.256	0.000
G20-G26 Extrapyramidal and movement disorders	0.744	0.256	0.000
K51.0 Ulcerative (chronic) enterocolitis	0.742	0.258	0.000
K22.8 Other specified diseases of oesophagus	0.742	0.258	0.000
E78.2 Mixed hyperlipidaemia	0.738	0.262	0.000
K05 Gingivitis and periodontal diseases	0.736	0.264	0.000
K14 Diseases of tongue	0.736	0.264	0.000
J32.4 Chronic pansinusitis	0.735	0.265	0.000
R25.8 Other and unspecified abnormal involuntary movements	0.735	0.265	0.000
S42 Fracture of shoulder and upper arm	0.735	0.265	0.000
J86 Pyothorax	0.734	0.265	0.000
I21 Acute myocardial infarction	0.733	0.267	0.000
T79 Certain early complications of trauma, not elsewhere classified	0.733	0.267	0.000
I08.1 Disorders of both mitral and tricuspid valves	0.733	0.267	0.000
N64.4 Mastodynia	0.732	0.268	0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.732	0.268	0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.732	0.268	0.000
K13 Other diseases of lip and oral mucosa	0.732	0.268	0.000
H61.0 Perichondritis of external ear	0.731	0.269	0.000
S50-S59 Injuries to the elbow and forearm	0.729	0.270	0.000
K22.0 Achalasia of cardia	0.728	0.272	0.000
R04.2 Haemoptysis	0.727	0.273	0.000
E10-E14 Diabetes mellitus	0.727	0.273	0.000
K60.1 Chronic anal fissure	0.725	0.275	0.000
K63.9 Disease of intestine, unspecified	0.724	0.276	0.000
Chapter XII Diseases of the skin and subcutaneous tissue	0.724	0.276	0.000
G56 Mononeuropathies of upper limb	0.723	0.277	0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified	0.722	0.278	0.000
K12.0 Recurrent oral aphthae	0.722	0.278	0.000
H54 Blindness and low vision	0.721	0.279	0.000
N10 Acute tubulo-interstitial nephritis	0.721	0.279	0.000
H02 Other disorders of eyelid	0.720	0.280	0.000
N20.1 Calculus of ureter	0.719	0.281	0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.718	0.282	0.000
J44 Other chronic obstructive pulmonary disease	0.718	0.282	0.000
K65-K67 Diseases of peritoneum	0.717	0.283	0.000
K51.1 Ulcerative (chronic) ileocolitis	0.717	0.283	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283	0.000
K64 Haemorrhoids and perianal venous thrombosis	0.717	0.283	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.717	0.283	0.000
E00 Congenital iodine-deficiency syndrome	0.717	0.283	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.717	0.283	0.000
E03.8 Other specified hypothyroidism	0.717	0.283	0.000
E03.5 Myxoedema coma	0.717	0.283	0.000
E03.4 Atrophy of thyroid (acquired)	0.717	0.283	0.000
E03.3 Postinfectious hypothyroidism	0.717	0.283	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.717	0.283	0.000
E03.1 Congenital hypothyroidism without goitre	0.717	0.283	0.000
E03.0 Congenital hypothyroidism with diffuse goitre	0.717	0.283	0.000
K59.8 Other specified functional intestinal disorders	0.716	0.284	0.000
R95-R99 Ill-defined and unknown causes of mortality	0.716	0.284	0.000
R36 Urethral discharge	0.716	0.284	0.000
K28 Gastrojejunal ulcer	0.715	0.285	0.000
K23 Disorders of oesophagus in diseases classified elsewhere	0.715	0.285	0.000
H69 Other disorders of Eustachian tube	0.715	0.285	0.000
J37 Chronic laryngitis and laryngotracheitis	0.715	0.285	0.000
K55 Vascular disorders of intestine	0.714	0.285	0.000
F33.1 Recurrent depressive disorder, current episode moderate	0.714	0.285	0.000
Chapter XXII Codes for special purposes	0.714	0.286	0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.714	0.286	0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.713	0.287	0.000
H70 Mastoiditis and related conditions	0.713	0.287	0.000
H68 Eustachian salpingitis and obstruction	0.713	0.287	0.000
H67 Otitis media in diseases classified elsewhere	0.713	0.287	0.000
S09 Other and unspecified injuries of head	0.713	0.287	0.000
Z93.1 Gastrostomy status	0.713	0.287	0.000
E85 Amyloidosis	0.713	0.287	0.000
E84 Cystic fibrosis	0.713	0.287	0.000
E79 Disorders of purine and pyrimidine metabolism	0.713	0.287	0.000
E77 Disorders of glycoprotein metabolism	0.713	0.287	0.000
E76 Disorders of glycosaminoglycan metabolism	0.713	0.287	0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.713	0.287	0.000
E74 Other disorders of carbohydrate metabolism	0.713	0.287	0.000
E73 Lactose intolerance	0.713	0.287	0.000
E72 Other disorders of amino-acid metabolism	0.713	0.287	0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.713	0.287	0.000
E70 Disorders of aromatic amino-acid metabolism	0.713	0.287	0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.713	0.287	0.000
T33-T35 Frostbite	0.712	0.287	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.712	0.287	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.712	0.287	0.000
T00-T07 Injuries involving multiple body regions	0.712	0.287	0.000
J21 Acute bronchiolitis	0.711	0.289	0.000
J69.0 Pneumonitis due to food and vomit	0.711	0.289	0.000
C44.6 Skin of upper limb, including shoulder	0.710	0.290	0.000
E78.8 Other disorders of lipoprotein metabolism	0.710	0.290	0.000
E78.6 Lipoprotein deficiency	0.710	0.290	0.000
E78.4 Other hyperlipidaemia	0.710	0.290	0.000
E78.3 Hyperchylomicronaemia	0.710	0.290	0.000
E78.1 Pure hyperglyceridaemia	0.710	0.290	0.000
K09 Cysts of oral region, not elsewhere classified	0.710	0.290	0.000
K52.2 Allergic and dietetic gastro-enteritis and colitis	0.708	0.292	0.000
K52.0 Gastro-enteritis and colitis due to radiation	0.708	0.292	0.000
K60.5 Anorectal fistula	0.707	0.293	0.000
K60.4 Rectal fistula	0.707	0.293	0.000
K60.0 Acute anal fissure	0.707	0.293	0.000
N50.8 Other specified disorders of male genital organs	0.705	0.295	0.000
N22 Calculus of urinary tract in diseases classified elsewhere	0.704	0.296	0.000
J31.1 Chronic nasopharyngitis	0.702	0.298	0.000
K61.4 Intrasphincteric abscess	0.701	0.298	0.000
K61.2 Anorectal abscess	0.701	0.298	0.000
K61.1 Rectal abscess	0.701	0.298	0.000
R09.3 Abnormal sputum	0.701	0.299	0.000
C43 Malignant melanoma of skin	0.700	0.300	0.000
R09.1 Pleurisy	0.700	0.300	0.000
R27 Other lack of coordination	0.700	0.300	0.000
J30 Vasomotor and allergic rhinitis	0.700	0.300	0.000
H60 Otitis externa	0.699	0.301	0.000
E87.6 Hypokalaemia	0.699	0.301	0.000
N20.9 Urinary calculus, unspecified	0.698	0.302	0.000
J20 Acute bronchitis	0.697	0.303	0.000
N43 Hydrocele and spermatocele	0.696	0.304	0.000
K22.9 Disease of oesophagus, unspecified	0.696	0.304	0.000
H20 Iridocyclitis	0.696	0.304	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.695	0.305	0.000
J32.2 Chronic ethmoidal sinusitis	0.694	0.305	0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.694	0.306	0.000
H66 Suppurative and unspecified otitis media	0.693	0.307	0.000
G56.2 Lesion of ulnar nerve	0.693	0.307	0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.692	0.308	0.000
K63.4 Enteroptosis	0.691	0.309	0.000
S06 Intracranial injury	0.690	0.310	0.000
J32.3 Chronic sphenoidal sinusitis	0.689	0.310	0.000
J32.1 Chronic frontal sinusitis	0.689	0.310	0.000
K59.3 Megacolon, not elsewhere classified	0.689	0.311	0.000
N40 Hyperplasia of prostate	0.689	0.311	0.000
H02.9 Disorder of eyelid, unspecified	0.687	0.313	0.000
L00-L08 Infections of the skin and subcutaneous tissue	0.685	0.315	0.000
S02.20 Fracture of nasal bones (closed)	0.684	0.316	0.000
K62.4 Stenosis of anus and rectum	0.683	0.316	0.000
S40 Superficial injury of shoulder and upper arm	0.683	0.317	0.000
E87.0 Hyperosmolality and hypernatraemia	0.683	0.317	0.000
F33.9 Recurrent depressive disorder, unspecified	0.681	0.319	0.000
Q80-Q89 Other congenital malformations	0.680	0.320	0.000
K27.9 Unspecified as acute or chronic, without haemorrhage or perforation	0.679	0.321	0.000
I08.0 Disorders of both mitral and aortic valves	0.679	0.321	0.000
I21.9 Acute myocardial infarction, unspecified	0.678	0.322	0.000
G70-G73 Diseases of myoneural junction and muscle	0.678	0.322	0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.677	0.322	0.000
Chapter I Certain infectious and parasitic diseases	0.677	0.323	0.000
J34.1 Cyst and mucocele of nose and nasal sinus	0.677	0.323	0.000
G80-G83 Cerebral palsy and other paralytic syndromes	0.676	0.324	0.000
G58 Other mononeuropathies	0.676	0.324	0.000
N30.9 Cystitis, unspecified	0.675	0.325	0.000
N30.1 Interstitial cystitis (chronic)	0.675	0.325	0.000
H65.9 Nonsuppurative otitis media, unspecified	0.674	0.326	0.000
N99.9 Postprocedural disorder of genito-urinary system, unspecified	0.674	0.326	0.000
N99.5 Malfunction of external stoma of urinary tract	0.674	0.326	0.000
N99.2 Postprocedural adhesions of vagina	0.674	0.326	0.000
N99.1 Postprocedural urethral stricture	0.674	0.326	0.000
K63.3 Ulcer of intestine	0.674	0.326	0.000
H72.8 Other perforations of tympanic membrane	0.673	0.327	0.000
Z93.3 Colostomy status	0.672	0.328	0.000
J35.8 Other chronic diseases of tonsils and adenoids	0.671	0.329	0.000
G57 Mononeuropathies of lower limb	0.671	0.329	0.000
N42 Other disorders of prostate	0.671	0.329	0.000
H74.8 Other specified disorders of middle ear and mastoid	0.671	0.329	0.000
H72.2 Other marginal perforations of tympanic membrane	0.670	0.330	0.000
H72.1 Attic perforation of tympanic membrane	0.670	0.330	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.670	0.330	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.670	0.330	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.670	0.330	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.670	0.330	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.670	0.330	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.670	0.330	0.000
T36 Poisoning by systemic antibiotics	0.670	0.330	0.000
H62 Disorders of external ear in diseases classified elsewhere	0.669	0.331	0.000
H46-H48 Disorders of optic nerve and visual pathways	0.669	0.331	0.000
S42.0 Fracture of clavicle	0.667	0.333	0.000
F30.9 Manic episode, unspecified	0.666	0.334	0.000
T78 Adverse effects, not elsewhere classified	0.666	0.334	0.000
K21 Gastro-oesophageal reflux disease	0.666	0.334	0.000
S02.6 Fracture of mandible	0.665	0.335	0.000
S02.5 Fracture of tooth	0.665	0.335	0.000
K06 Other disorders of gingiva and edentulous alveolar ridge	0.665	0.335	0.000
N23 Unspecified renal colic	0.665	0.335	0.000
K42 Umbilical hernia	0.664	0.336	0.000
N63 Unspecified lump in breast	0.664	0.336	0.000
G95 Other diseases of spinal cord	0.664	0.336	0.000
I27 Other pulmonary heart diseases	0.663	0.337	0.000
C44.0 Skin of lip	0.663	0.337	0.000
J42 Unspecified chronic bronchitis	0.663	0.337	0.000
K03 Other diseases of hard tissues of teeth	0.662	0.337	0.000
K00 Disorders of tooth development and eruption	0.662	0.337	0.000
C83.3 Large cell (diffuse)	0.661	0.339	0.000
H91 Other hearing loss	0.661	0.339	0.000
K26 Duodenal ulcer	0.661	0.339	0.000
Q00-Q07 Congenital malformations of the nervous system	0.660	0.340	0.000
T14 Injury of unspecified body region	0.660	0.340	0.000
N11 Chronic tubulo-interstitial nephritis	0.660	0.340	0.000
K22.1 Ulcer of oesophagus	0.660	0.340	0.000
S02.1 Fracture of base of skull	0.660	0.340	0.000
C44.2 Skin of ear and external auricular canal	0.659	0.341	0.000
R09.8 Other specified symptoms and signs involving the circulatory and respiratory systems	0.659	0.341	0.000
K08 Other disorders of teeth and supporting structures	0.659	0.341	0.000
H93 Other disorders of ear, not elsewhere classified	0.658	0.342	0.000
I95-I99 Other and unspecified disorders of the circulatory system	0.658	0.342	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.657	0.343	0.000
H10-H13 Disorders of conjunctiva	0.657	0.343	0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.656	0.343	0.000
N45 Orchitis and epididymitis	0.656	0.344	0.000
N64.5 Other signs and symptoms in breast	0.656	0.344	0.000
J34.0 Abscess, furuncle and carbuncle of nose	0.656	0.344	0.000
I20 Angina pectoris	0.656	0.344	0.000
J86.9 Pyothorax without fistula	0.655	0.345	0.000
S70-S79 Injuries to the hip and thigh	0.655	0.345	0.000
S90-S99 Injuries to the ankle and foot	0.653	0.347	0.000
N39 Other disorders of urinary system	0.653	0.347	0.000
Q54 Hypospadias	0.653	0.347	0.000
E05 Thyrotoxicosis [hyperthyroidism]	0.653	0.347	0.000
T43.2 Other and unspecified antidepressants	0.652	0.348	0.000
K12.3 Oral mucositis (ulcerative)	0.652	0.348	0.000
F60-F69 Disorders of adult personality and behaviour	0.651	0.349	0.000
N30.3 Trigonitis	0.651	0.349	0.000
E06.9 Thyroiditis, unspecified	0.650	0.350	0.000
E06.5 Other chronic thyroiditis	0.650	0.350	0.000
E06.4 Drug-induced thyroiditis	0.650	0.350	0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.650	0.350	0.000
E06.1 Subacute thyroiditis	0.650	0.350	0.000
E06.0 Acute thyroiditis	0.650	0.350	0.000
N64.3 Galactorrhoea not associated with childbirth	0.649	0.351	0.000
N64.2 Atrophy of breast	0.649	0.351	0.000
N64.0 Fissure and fistula of nipple	0.649	0.351	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.649	0.351	0.000
N71 Inflammatory disease of uterus, except cervix	0.648	0.352	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.648	0.352	0.000
J32.0 Chronic maxillary sinusitis	0.646	0.354	0.000
R25.3 Fasciculation	0.646	0.354	0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere	0.645	0.355	0.000
N15 Other renal tubulo-interstitial diseases	0.645	0.355	0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions	0.645	0.355	0.000
R26.8 Other and unspecified abnormalities of gait and mobility	0.645	0.355	0.000
E07.9 Disorder of thyroid, unspecified	0.645	0.355	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.645	0.355	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.645	0.355	0.000
Q35-Q37 Cleft lip and cleft palate	0.645	0.355	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.645	0.355	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.645	0.355	0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.645	0.355	0.000
R39 Other symptoms and signs involving the urinary system	0.644	0.356	0.000
S22 Fracture of rib(s), sternum and thoracic spine	0.644	0.356	0.000
R09.2 Respiratory arrest	0.643	0.357	0.000
K22.3 Perforation of oesophagus	0.641	0.358	0.000
F31 Bipolar affective disorder	0.641	0.359	0.000
E11 Non-insulin-dependent diabetes mellitus	0.641	0.359	0.000
S02.4 Fracture of malar and maxillary bones	0.640	0.359	0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.640	0.360	0.000
N99.4 Postprocedural pelvic peritoneal adhesions	0.639	0.361	0.000
C44.9 Malignant neoplasm of skin, unspecified	0.639	0.361	0.000
H74.0 Tympanosclerosis	0.638	0.362	0.000
N36 Other disorders of urethra	0.638	0.362	0.000
I05 Rheumatic mitral valve diseases	0.637	0.363	0.000
K10.2 Inflammatory conditions of jaws	0.637	0.363	0.000
S27 Injury of other and unspecified intrathoracic organs	0.636	0.364	0.000
S08 Traumatic amputation of part of head	0.636	0.364	0.000
S07 Crushing injury of head	0.636	0.364	0.000
S05 Injury of eye and orbit	0.636	0.364	0.000
S04 Injury of cranial nerves	0.636	0.364	0.000
S03 Dislocation, sprain and strain of joints and ligaments of head	0.636	0.364	0.000
C56 Malignant neoplasm of ovary	0.636	0.364	0.000
R01 Cardiac murmurs and other cardiac sounds	0.636	0.364	0.000
G93 Other disorders of brain	0.636	0.364	0.000
G00-G09 Inflammatory diseases of the central nervous system	0.636	0.364	0.000
I22 Subsequent myocardial infarction	0.635	0.365	0.000
N51 Disorders of male genital organs in diseases classified elsewhere	0.635	0.365	0.000
N46 Male infertility	0.635	0.365	0.000
N44 Torsion of testis	0.635	0.365	0.000
E55 Vitamin D deficiency	0.634	0.366	0.000
K59.9 Functional intestinal disorder, unspecified	0.634	0.366	0.000
K59.4 Anal spasm	0.634	0.366	0.000
K59.2 Neurogenic bowel, not elsewhere classified	0.634	0.366	0.000
K93 Disorders of other digestive organs in diseases classified elsewhere	0.600	0.366	0.034
K43 Ventral hernia	0.633	0.366	0.000
J41 Simple and mucopurulent chronic bronchitis	0.633	0.367	0.000
H65.4 Other chronic nonsuppurative otitis media	0.632	0.367	0.000
T18 Foreign body in alimentary tract	0.632	0.367	0.000
R82 Other abnormal findings in urine	0.632	0.368	0.000
H61.9 Disorder of external ear, unspecified	0.632	0.368	0.000
H61.8 Other specified disorders of external ear	0.632	0.368	0.000
H61.3 Acquired stenosis of external ear canal	0.632	0.368	0.000
H61.1 Non-infective disorders of pinna	0.632	0.368	0.000
J00-J06 Acute upper respiratory infections	0.631	0.369	0.000
S49 Other and unspecified injuries of shoulder and upper arm	0.629	0.371	0.000
S48 Traumatic amputation of shoulder and upper arm	0.629	0.371	0.000
S46 Injury of muscle and tendon at shoulder and upper arm level	0.629	0.371	0.000
S45 Injury of blood vessels at shoulder and upper arm level	0.629	0.371	0.000
S44 Injury of nerves at shoulder and upper arm level	0.629	0.371	0.000
S41 Open wound of shoulder and upper arm	0.629	0.371	0.000
S47 Crushing injury of shoulder and upper arm	0.629	0.371	0.000
Q25 Congenital malformations of great arteries	0.629	0.371	0.000
I21.1 Acute transmural myocardial infarction of inferior wall	0.628	0.372	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.627	0.373	0.000
H65.1 Other acute nonsuppurative otitis media	0.627	0.373	0.000
H65.0 Acute serous otitis media	0.627	0.373	0.000
K12.2 Cellulitis and abscess of mouth	0.626	0.374	0.000
C40-C41 Malignant neoplasms of bone and articular cartilage	0.626	0.374	0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.626	0.374	0.000
F70-F79 Mental retardation	0.626	0.374	0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified	0.625	0.375	0.000
S30 Superficial injury of abdomen, lower back and pelvis	0.625	0.375	0.000
L02 Cutaneous abscess, furuncle and carbuncle	0.625	0.375	0.000
C92 Myeloid leukaemia	0.625	0.375	0.000
N49 Inflammatory disorders of male genital organs, not elsewhere classified	0.625	0.375	0.000
N21 Calculus of lower urinary tract	0.624	0.376	0.000
R09.0 Asphyxia	0.624	0.376	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations