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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs115044935
log Bayes Factor = 24.1643
Chromosome 3   position 175,446,721  (GRCh37) Explore rs115044935 on Ensembl!
Variant rs115044935 is part of Cluster X0059

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter II Neoplasms
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
1.000 0.000 0.000
Chapter I Certain infectious and parasitic diseases
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
C50-C50 Malignant neoplasm of breast
0.999 0.001 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.999 0.001 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.998 0.002 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.998 0.002 0.000
C50 Malignant neoplasm of breast
0.998 0.002 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.997 0.003 0.000
Chapter VI Diseases of the nervous system
0.997 0.003 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.996 0.004 0.000
Chapter XXI Factors influencing health status and contact with health services
0.994 0.006 0.000
E70-E90 Metabolic disorders
0.994 0.006 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.993 0.007 0.000
C77.3 Axillary and upper limb lymph nodes
0.993 0.007 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.991 0.009 0.000
G90-G99 Other disorders of the nervous system
0.989 0.011 0.000
I30-I52 Other forms of heart disease
0.988 0.012 0.000
Z51 Other medical care
0.988 0.012 0.000
Chapter X Diseases of the respiratory system
0.986 0.014 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.986 0.014 0.000
I77 Other disorders of arteries and arterioles
0.986 0.014 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.984 0.016 0.000
A30-A49 Other bacterial diseases
0.982 0.018 0.000
Z51.0 Radiotherapy session
0.982 0.018 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.981 0.019 0.000
J90-J94 Other diseases of pleura
0.981 0.019 0.000
C79 Secondary malignant neoplasm of other sites
0.978 0.022 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.973 0.027 0.000
I49 Other cardiac arrhythmias
0.972 0.028 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.971 0.029 0.000
A41 Other septicaemia
0.971 0.029 0.000
J90 Pleural effusion, not elsewhere classified
0.961 0.039 0.000
C50.4 Upper-outer quadrant of breast
0.960 0.040 0.000
M50-M54 Other dorsopathies
0.954 0.046 0.000
C78.0 Secondary malignant neoplasm of lung
0.951 0.049 0.000
J09-J18 Influenza and pneumonia
0.949 0.051 0.000
I49.9 Cardiac arrhythmia, unspecified
0.937 0.063 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.936 0.064 0.000
E87.7 Fluid overload
0.936 0.064 0.000
M54 Dorsalgia
0.935 0.065 0.000
C50.9 Breast, unspecified
0.931 0.069 0.000
I71 Aortic aneurysm and dissection
0.931 0.069 0.000
D70 Agranulocytosis
0.930 0.070 0.000
Z45 Adjustment and management of implanted device
0.930 0.070 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.929 0.071 0.000
J18 Pneumonia, organism unspecified
0.928 0.072 0.000
E86 Volume depletion
0.927 0.073 0.000
B95-B98 Bacterial, viral and other infectious agents
0.927 0.073 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.926 0.074 0.000
A00-A09 Intestinal infectious diseases
0.925 0.075 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.925 0.075 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.923 0.077 0.000
I77.6 Arteritis, unspecified
0.922 0.078 0.000
S20-S29 Injuries to the thorax
0.921 0.079 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.919 0.081 0.000
M54.5 Low back pain
0.918 0.082 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.915 0.085 0.000
I42 Cardiomyopathy
0.913 0.087 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.911 0.089 0.000
A41.0 Septicaemia due to Staphylococcus aureus
0.911 0.089 0.000
I77.1 Stricture of artery
0.910 0.090 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.909 0.091 0.000
B35-B49 Mycoses
0.909 0.091 0.000
J18.9 Pneumonia, unspecified
0.908 0.092 0.000
R80 Isolated proteinuria
0.908 0.092 0.000
B15-B19 Viral hepatitis
0.907 0.093 0.000
C77.5 Intrapelvic lymph nodes
0.907 0.093 0.000
A41.9 Septicaemia, unspecified
0.906 0.094 0.000
D45 Polycythaemia vera
0.904 0.096 0.000
J91 Pleural effusion in conditions classified elsewhere
0.904 0.096 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.903 0.097 0.000
C50.5 Lower-outer quadrant of breast
0.902 0.098 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.900 0.100 0.000
D50-D53 Nutritional anaemias
0.899 0.101 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.897 0.103 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.894 0.106 0.000
G91 Hydrocephalus
0.893 0.107 0.000
C50.8 Overlapping lesion of breast
0.893 0.107 0.000
M54.59 Low back pain (Site unspecified)
0.887 0.113 0.000
Z51.5 Palliative care
0.886 0.114 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.884 0.116 0.000
E20-E35 Disorders of other endocrine glands
0.882 0.118 0.000
Chapter XXII Codes for special purposes
0.882 0.118 0.000
I49.5 Sick sinus syndrome
0.881 0.119 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.880 0.120 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.880 0.120 0.000
D41.4 Bladder
0.878 0.122 0.000
E10-E14 Diabetes mellitus
0.877 0.123 0.000
J94 Other pleural conditions
0.876 0.124 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.876 0.124 0.000
Z49 Care involving dialysis
0.875 0.125 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.874 0.126 0.000
Z51.8 Other specified medical care
0.871 0.129 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.869 0.131 0.000
I60-I69 Cerebrovascular diseases
0.868 0.132 0.000
Z45.8 Adjustment and management of other implanted devices
0.867 0.133 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.865 0.135 0.000
A04 Other bacterial intestinal infections
0.863 0.137 0.000
L90 Atrophic disorders of skin
0.860 0.140 0.000
D72 Other disorders of white blood cells
0.859 0.141 0.000
D75 Other diseases of blood and blood-forming organs
0.859 0.141 0.000
R73 Elevated blood glucose level
0.858 0.142 0.000
G99.2 Myelopathy in diseases classified elsewhere
0.854 0.146 0.000
R94 Abnormal results of function studies
0.854 0.146 0.000
E87.2 Acidosis
0.853 0.147 0.000
M20-M25 Other joint disorders
0.852 0.148 0.000
E83 Disorders of mineral metabolism
0.852 0.148 0.000
G95 Other diseases of spinal cord
0.851 0.149 0.000
D80-D89 Certain disorders involving the immune mechanism
0.848 0.152 0.000
C50.2 Upper-inner quadrant of breast
0.848 0.152 0.000
D10-D36 Benign neoplasms
0.848 0.152 0.000
S40-S49 Injuries to the shoulder and upper arm
0.847 0.153 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.845 0.155 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.845 0.155 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.843 0.157 0.000
I72 Other aneurysm
0.843 0.157 0.000
M45-M49 Spondylopathies
0.842 0.158 0.000
I47 Paroxysmal tachycardia
0.841 0.159 0.000
I46 Cardiac arrest
0.839 0.161 0.000
E10 Insulin-dependent diabetes mellitus
0.838 0.162 0.000
C77.1 Intrathoracic lymph nodes
0.838 0.162 0.000
S60-S69 Injuries to the wrist and hand
0.836 0.164 0.000
I73 Other peripheral vascular diseases
0.836 0.164 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.834 0.166 0.000
Z50 Care involving use of rehabilitation procedures
0.833 0.167 0.000
L90.5 Scar conditions and fibrosis of skin
0.832 0.168 0.000
Z22 Carrier of infectious disease
0.830 0.170 0.000
C34 Malignant neoplasm of bronchus and lung
0.830 0.170 0.000
L82 Seborrhoeic keratosis
0.829 0.171 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.828 0.172 0.000
D69 Purpura and other haemorrhagic conditions
0.827 0.173 0.000
R73.9 Hyperglycaemia, unspecified
0.827 0.173 0.000
M60-M63 Disorders of muscles
0.827 0.173 0.000
M05-M14 Inflammatory polyarthropathies
0.826 0.174 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.826 0.174 0.000
L89 Decubitus ulcer
0.826 0.174 0.000
M25 Other joint disorders, not elsewhere classified
0.825 0.175 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.825 0.175 0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)
0.823 0.177 0.000
B37 Candidiasis
0.823 0.177 0.000
D51 Vitamin B12 deficiency anaemia
0.821 0.179 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.821 0.179 0.000
C78.2 Secondary malignant neoplasm of pleura
0.820 0.180 0.000
R47-R49 Symptoms and signs involving speech and voice
0.820 0.180 0.000
S10-S19 Injuries to the neck
0.819 0.181 0.000
I71.0 Dissection of aorta [any part]
0.819 0.181 0.000
R20 Disturbances of skin sensation
0.818 0.182 0.000
G91.9 Hydrocephalus, unspecified
0.818 0.182 0.000
E88 Other metabolic disorders
0.816 0.184 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.816 0.184 0.000
I70 Atherosclerosis
0.815 0.185 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.814 0.185 0.000
S70-S79 Injuries to the hip and thigh
0.813 0.187 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.812 0.188 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.812 0.188 0.000
A04.7 Enterocolitis due to Clostridium difficile
0.811 0.189 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.810 0.190 0.000
Z42 Follow-up care involving plastic surgery
0.805 0.195 0.000
M86-M90 Other osteopathies
0.805 0.195 0.000
M25.5 Pain in joint
0.804 0.196 0.000
B18 Chronic viral hepatitis
0.802 0.198 0.000
G96 Other disorders of central nervous system
0.798 0.202 0.000
G30-G32 Other degenerative diseases of the nervous system
0.798 0.202 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.798 0.202 0.000
M80-M85 Disorders of bone density and structure
0.797 0.203 0.000
G03 Meningitis due to other and unspecified causes
0.796 0.203 0.000
I42.1 Obstructive hypertrophic cardiomyopathy
0.792 0.208 0.000
M70-M79 Other soft tissue disorders
0.791 0.209 0.000
S20 Superficial injury of thorax
0.791 0.209 0.000
J94.8 Other specified pleural conditions
0.790 0.210 0.000
M91-M94 Chondropathies
0.788 0.212 0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.788 0.212 0.000
J18.1 Lobar pneumonia, unspecified
0.787 0.213 0.000
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters
0.786 0.214 0.000
I35 Nonrheumatic aortic valve disorders
0.784 0.216 0.000
D46 Myelodysplastic syndromes
0.783 0.217 0.000
R94.3 Abnormal results of cardiovascular function studies
0.782 0.218 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.781 0.219 0.000
Z22.3 Carrier of other specified bacterial diseases
0.779 0.221 0.000
C60-C63 Malignant neoplasms of male genital organs
0.778 0.222 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.777 0.223 0.000
C51-C58 Malignant neoplasms of female genital organs
0.776 0.224 0.000
A41.8 Other specified septicaemia
0.776 0.224 0.000
M25.56 Pain in joint (Lower leg)
0.776 0.224 0.000
G93 Other disorders of brain
0.775 0.224 0.000
C80 Malignant neoplasm without specification of site
0.774 0.226 0.000
B25-B34 Other viral diseases
0.773 0.227 0.000
B37.8 Candidiasis of other sites
0.772 0.228 0.000
I42.0 Dilated cardiomyopathy
0.770 0.230 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.770 0.230 0.000
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters
0.769 0.231 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.768 0.232 0.000
G63.2 Diabetic polyneuropathy
0.768 0.232 0.000
C77.4 Inguinal and lower limb lymph nodes
0.767 0.232 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.766 0.234 0.000
I99 Other and unspecified disorders of circulatory system
0.763 0.237 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.761 0.239 0.000
E83.5 Disorders of calcium metabolism
0.760 0.240 0.000
D13 Benign neoplasm of other and ill-defined parts of digestive system
0.760 0.240 0.000
C77.8 Lymph nodes of multiple regions
0.760 0.240 0.000
Z47 Other orthopaedic follow-up care
0.760 0.240 0.000
E27 Other disorders of adrenal gland
0.758 0.242 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.758 0.242 0.000
M50 Cervical disk disorders
0.756 0.244 0.000
A41.2 Septicaemia due to unspecified staphylococcus
0.756 0.244 0.000
Z52 Donors of organs and tissues
0.755 0.245 0.000
B65-B83 Helminthiases
0.755 0.245 0.000
C50.1 Central portion of breast
0.754 0.246 0.000
Z54 Convalescence
0.753 0.247 0.000
Z49.1 Extracorporeal dialysis
0.753 0.247 0.000
I73.0 Raynaud's syndrome
0.752 0.248 0.000
R49 Voice disturbances
0.752 0.248 0.000
M54.1 Radiculopathy
0.752 0.248 0.000
Z50.1 Other physical therapy
0.751 0.249 0.000
E10.9 Without complications
0.751 0.249 0.000
R20.2 Paraesthesia of skin
0.750 0.250 0.000
D72.8 Other specified disorders of white blood cells
0.750 0.250 0.000
Z48 Other surgical follow-up care
0.749 0.250 0.000
S60 Superficial injury of wrist and hand
0.749 0.251 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.749 0.251 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.748 0.252 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.748 0.252 0.000
G90 Disorders of autonomic nervous system
0.748 0.252 0.000
D47.1 Chronic myeloproliferative disease
0.746 0.254 0.000
Z45.0 Adjustment and management of cardiac pacemaker
0.746 0.254 0.000
B17 Other acute viral hepatitis
0.745 0.255 0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified
0.745 0.255 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.745 0.255 0.000
T79-T79 Certain early complications of trauma
0.743 0.257 0.000
I74 Arterial embolism and thrombosis
0.743 0.257 0.000
Chapter XX External causes of morbidity and mortality
0.743 0.257 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.739 0.261 0.000
I61 Intracerebral haemorrhage
0.738 0.262 0.000
G70-G73 Diseases of myoneural junction and muscle
0.738 0.262 0.000
R30-R39 Symptoms and signs involving the urinary system
0.738 0.262 0.000
I62 Other nontraumatic intracranial haemorrhage
0.737 0.263 0.000
E87.5 Hyperkalaemia
0.736 0.264 0.000
S62 Fracture at wrist and hand level
0.736 0.264 0.000
C77.9 Lymph node, unspecified
0.734 0.266 0.000
D55-D59 Haemolytic anaemias
0.734 0.266 0.000
E29 Testicular dysfunction
0.732 0.268 0.000
C32 Malignant neoplasm of larynx
0.731 0.269 0.000
A41.1 Septicaemia due to other specified staphylococcus
0.731 0.269 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.731 0.269 0.000
E40-E46 Malnutrition
0.730 0.270 0.000
C34.9 Bronchus or lung, unspecified
0.730 0.270 0.000
G08 Intracranial and intraspinal phlebitis and thrombophlebitis
0.730 0.270 0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.729 0.271 0.000
L89.1 Stage II decubitus ulcer
0.729 0.271 0.000
M00-M03 Infectious arthropathies
0.729 0.271 0.000
M24 Other specific joint derangements
0.728 0.272 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.727 0.272 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.726 0.274 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.726 0.274 0.000
I31 Other diseases of pericardium
0.724 0.276 0.000
I77.8 Other specified disorders of arteries and arterioles
0.722 0.278 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.721 0.279 0.000
G99.0 Autonomic neuropathy in endocrine and metabolic diseases
0.720 0.280 0.000
A08 Viral and other specified intestinal infections
0.720 0.280 0.000
D73 Diseases of spleen
0.720 0.280 0.000
I49.3 Ventricular premature depolarisation
0.719 0.281 0.000
I44 Atrioventricular and left bundle-branch block
0.719 0.281 0.000
M22 Disorders of patella
0.718 0.282 0.000
A46 Erysipelas
0.717 0.283 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.717 0.283 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.717 0.283 0.000
B99-B99 Other infectious diseases
0.717 0.283 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.717 0.283 0.000
B50-B64 Protozoal diseases
0.717 0.283 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.717 0.283 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.717 0.283 0.000
A75-A79 Rickettsioses
0.717 0.283 0.000
A70-A74 Other diseases caused by chlamydiae
0.717 0.283 0.000
A65-A69 Other spirochaetal diseases
0.717 0.283 0.000
A20-A28 Certain zoonotic bacterial diseases
0.717 0.283 0.000
A15-A19 Tuberculosis
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
G03.9 Meningitis, unspecified
0.716 0.284 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.716 0.284 0.000
C50.6 Axillary tail of breast
0.715 0.284 0.000
C50.0 Nipple and areola
0.715 0.284 0.000
E87.3 Alkalosis
0.715 0.285 0.000
I49.8 Other specified cardiac arrhythmias
0.714 0.286 0.000
E28 Ovarian dysfunction
0.713 0.287 0.000
E85 Amyloidosis
0.713 0.287 0.000
E84 Cystic fibrosis
0.713 0.287 0.000
E79 Disorders of purine and pyrimidine metabolism
0.713 0.287 0.000
E77 Disorders of glycoprotein metabolism
0.713 0.287 0.000
E76 Disorders of glycosaminoglycan metabolism
0.713 0.287 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.713 0.287 0.000
E74 Other disorders of carbohydrate metabolism
0.713 0.287 0.000
E73 Lactose intolerance
0.713 0.287 0.000
E72 Other disorders of amino-acid metabolism
0.713 0.287 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.713 0.287 0.000
E70 Disorders of aromatic amino-acid metabolism
0.713 0.287 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.713 0.287 0.000
B44 Aspergillosis
0.712 0.287 0.000
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified
0.712 0.288 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.712 0.288 0.000
Z44 Fitting and adjustment of external prosthetic device
0.712 0.288 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.711 0.289 0.000
M54.57 Low back pain (Lumbosacral region)
0.711 0.289 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.710 0.290 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.710 0.290 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.710 0.290 0.000
I47.9 Paroxysmal tachycardia, unspecified
0.709 0.290 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.709 0.291 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.709 0.291 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.709 0.291 0.000
G92 Toxic encephalopathy
0.709 0.291 0.000
M54.4 Lumbago with sciatica
0.709 0.291 0.000
C15-C26 Malignant neoplasms of digestive organs
0.708 0.291 0.000
I52 Other heart disorders in diseases classified elsewhere
0.708 0.292 0.000
I48 Atrial fibrillation and flutter
0.708 0.292 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.708 0.292 0.000
I41 Myocarditis in diseases classified elsewhere
0.708 0.292 0.000
I40 Acute myocarditis
0.708 0.292 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.708 0.292 0.000
I37 Pulmonary valve disorders
0.708 0.292 0.000
I36 Nonrheumatic tricuspid valve disorders
0.708 0.292 0.000
I32 Pericarditis in diseases classified elsewhere
0.708 0.292 0.000
Z51.9 Medical care, unspecified
0.708 0.292 0.000
Z51.6 Desensitisation to allergens
0.708 0.292 0.000
M75 Shoulder lesions
0.708 0.292 0.000
D75.1 Secondary polycythaemia
0.707 0.293 0.000
B18.2 Chronic viral hepatitis C
0.707 0.293 0.000
E87.4 Mixed disorder of acid-base balance
0.707 0.293 0.000
I77.5 Necrosis of artery
0.707 0.293 0.000
I77.4 Coeliac artery compression syndrome
0.707 0.293 0.000
I77.3 Arterial fibromuscular dysplasia
0.707 0.293 0.000
I77.2 Rupture of artery
0.707 0.293 0.000
I77.0 Arteriovenous fistula, acquired
0.707 0.293 0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.706 0.294 0.000
D74 Methaemoglobinaemia
0.706 0.294 0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.706 0.294 0.000
D71 Functional disorders of polymorphonuclear neutrophils
0.706 0.294 0.000
I47.2 Ventricular tachycardia
0.705 0.295 0.000
I30 Acute pericarditis
0.705 0.295 0.000
Z49.0 Preparatory care for dialysis
0.705 0.295 0.000
D75.8 Other specified diseases of blood and blood-forming organs
0.705 0.295 0.000
D25 Leiomyoma of uterus
0.705 0.295 0.000
A80-A89 Viral infections of the central nervous system
0.704 0.296 0.000
I49.0 Ventricular fibrillation and flutter
0.704 0.296 0.000
A48 Other bacterial diseases, not elsewhere classified
0.704 0.296 0.000
A44 Bartonellosis
0.704 0.296 0.000
A43 Nocardiosis
0.704 0.296 0.000
A42 Actinomycosis
0.704 0.296 0.000
A40 Streptococcal septicaemia
0.704 0.296 0.000
A39 Meningococcal infection
0.704 0.296 0.000
A37 Whooping cough
0.704 0.296 0.000
A36 Diphtheria
0.704 0.296 0.000
A32 Listeriosis
0.704 0.296 0.000
A31 Infection due to other mycobacteria
0.704 0.296 0.000
A30 Leprosy [Hansen's disease]
0.704 0.296 0.000
A38 Scarlet fever
0.704 0.296 0.000
A35 Other tetanus
0.704 0.296 0.000
A34 Obstetrical tetanus
0.704 0.296 0.000
A33 Tetanus neonatorum
0.704 0.296 0.000
D69.6 Thrombocytopenia, unspecified
0.704 0.296 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.704 0.296 0.000
R20.8 Other and unspecified disturbances of skin sensation
0.704 0.296 0.000
R49.0 Dysphonia
0.704 0.296 0.000
J93 Pneumothorax
0.703 0.297 0.000
S22.2 Fracture of sternum
0.703 0.297 0.000
E10.3 With ophthalmic complications
0.703 0.297 0.000
D86 Sarcoidosis
0.702 0.298 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.701 0.299 0.000
C79.6 Secondary malignant neoplasm of ovary
0.701 0.299 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.701 0.299 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.701 0.299 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.701 0.299 0.000
G04 Encephalitis, myelitis and encephalomyelitis
0.701 0.299 0.000
L83 Acanthosis nigricans
0.701 0.299 0.000
E16 Other disorders of pancreatic internal secretion
0.701 0.299 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.700 0.300 0.000
I05-I09 Chronic rheumatic heart diseases
0.700 0.300 0.000
O60-O75 Complications of labour and delivery
0.700 0.300 0.000
I72.8 Aneurysm of other specified arteries
0.700 0.300 0.000
Z50.8 Care involving use of rehabilitation procedures
0.700 0.300 0.000
S22.0 Fracture of thoracic vertebra
0.699 0.300 0.000
S50-S59 Injuries to the elbow and forearm
0.699 0.301 0.000
I46.9 Cardiac arrest, unspecified
0.699 0.301 0.000
R94.5 Abnormal results of liver function studies
0.698 0.302 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.698 0.302 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.698 0.302 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.698 0.302 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.698 0.302 0.000
R23 Other skin changes
0.697 0.302 0.000
M07 Psoriatic and enteropathic arthropathies
0.697 0.303 0.000
Z45.2 Adjustment and management of vascular access device
0.697 0.303 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.697 0.303 0.000
I49.2 Junctional premature depolarisation
0.697 0.303 0.000
I49.1 Atrial premature depolarisation
0.697 0.303 0.000
E10.4 With neurological complications
0.697 0.303 0.000
C34.0 Main bronchus
0.696 0.304 0.000
T33-T35 Frostbite
0.696 0.304 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.696 0.304 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.696 0.304 0.000
T00-T07 Injuries involving multiple body regions
0.696 0.304 0.000
A41.4 Septicaemia due to anaerobes
0.696 0.304 0.000
A41.3 Septicaemia due to Haemophilus influenzae
0.696 0.304 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.696 0.304 0.000
I35.1 Aortic (valve) insufficiency
0.694 0.306 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.694 0.306 0.000
G20-G26 Extrapyramidal and movement disorders
0.694 0.306 0.000
S40 Superficial injury of shoulder and upper arm
0.693 0.307 0.000
C05 Malignant neoplasm of palate
0.692 0.308 0.000
D22 Melanocytic naevi
0.691 0.309 0.000
M87 Osteonecrosis
0.691 0.309 0.000
I71.3 Abdominal aortic aneurysm, ruptured
0.690 0.310 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.689 0.311 0.000
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.689 0.311 0.000
Z41 Procedures for purposes other than remedying health state
0.688 0.311 0.000
I38 Endocarditis, valve unspecified
0.688 0.311 0.000
M25.55 Pain in joint (Pelvic region and thigh)
0.688 0.312 0.000
S90-S99 Injuries to the ankle and foot
0.688 0.312 0.000
I95 Hypotension
0.688 0.312 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.687 0.312 0.000
C34.3 Lower lobe, bronchus or lung
0.687 0.313 0.000
D47.2 Monoclonal gammopathy
0.686 0.314 0.000
E83.3 Disorders of phosphorus metabolism
0.686 0.314 0.000
M53 Other dorsopathies, not elsewhere classified
0.684 0.316 0.000
D50 Iron deficiency anaemia
0.684 0.316 0.000
I60 Subarachnoid haemorrhage
0.684 0.316 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.684 0.316 0.000
M48 Other spondylopathies
0.684 0.316 0.000
J00-J06 Acute upper respiratory infections
0.683 0.317 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.682 0.318 0.000
L40-L45 Papulosquamous disorders
0.682 0.318 0.000
I70.2 Atherosclerosis of arteries of the extremities
0.682 0.318 0.000
I42.2 Other hypertrophic cardiomyopathy
0.682 0.318 0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.681 0.319 0.000
R30 Pain associated with micturition
0.681 0.319 0.000
J17 Pneumonia in diseases classified elsewhere
0.680 0.319 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.680 0.319 0.000
J12 Viral pneumonia, not elsewhere classified
0.680 0.319 0.000
J10 Influenza due to identified influenza virus
0.680 0.319 0.000
J14 Pneumonia due to Haemophilus influenzae
0.680 0.319 0.000
J09 Influenza due to certain identified influenza virus
0.680 0.319 0.000
I33 Acute and subacute endocarditis
0.680 0.320 0.000
M30 Polyarteritis nodosa and related conditions
0.680 0.320 0.000
G95.0 Syringomyelia and syringobulbia
0.680 0.320 0.000
J60-J70 Lung diseases due to external agents
0.680 0.320 0.000
I42.9 Cardiomyopathy, unspecified
0.679 0.321 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.679 0.321 0.000
M40-M43 Deforming dorsopathies
0.679 0.321 0.000
L92 Granulomatous disorders of skin and subcutaneous tissue
0.676 0.324 0.000
G95.2 Cord compression, unspecified
0.675 0.324 0.000
D18 Haemangioma and lymphangioma, any site
0.675 0.325 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.675 0.325 0.000
S62.6 Fracture of other finger
0.675 0.325 0.000
S27 Injury of other and unspecified intrathoracic organs
0.674 0.326 0.000
M54.2 Cervicalgia
0.674 0.326 0.000
D69.5 Secondary thrombocytopenia
0.673 0.327 0.000
A04.8 Other specified bacterial intestinal infections
0.673 0.327 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.673 0.327 0.000
T66-T78 Other and unspecified effects of external causes
0.672 0.328 0.000
D68 Other coagulation defects
0.672 0.328 0.000
L50-L54 Urticaria and erythema
0.672 0.328 0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.672 0.328 0.000
S22.4 Multiple fractures of ribs
0.671 0.329 0.000
D69.3 Idiopathic thrombocytopenic purpura
0.671 0.329 0.000
M25.3 Other instability of joint
0.671 0.329 0.000
Z76 Persons encountering health services in other circumstances
0.671 0.329 0.000
Chapter VIII Diseases of the ear and mastoid process
0.670 0.330 0.000
M54.8 Other dorsalgia
0.670 0.330 0.000
M54.0 Panniculitis affecting regions of neck and back
0.670 0.330 0.000
T81 Complications of procedures, not elsewhere classified
0.669 0.331 0.000
U80 Agent resistant to penicillin and related antibiotics
0.669 0.331 0.000
M47 Spondylosis
0.669 0.331 0.000
J20-J22 Other acute lower respiratory infections
0.669 0.331 0.000
I71.8 Aortic aneurysm of unspecified site, ruptured
0.667 0.333 0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.667 0.333 0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.667 0.333 0.000
I71.1 Thoracic aortic aneurysm, ruptured
0.667 0.333 0.000
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified
0.667 0.333 0.000
L20-L30 Dermatitis and eczema
0.667 0.333 0.000
Z45.9 Adjustment and management of unspecified implanted device
0.667 0.333 0.000
Z45.3 Adjustment and management of implanted hearing device
0.667 0.333 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.666 0.334 0.000
C64-C68 Malignant neoplasms of urinary tract
0.666 0.334 0.000
J18.8 Other pneumonia, organism unspecified
0.665 0.335 0.000
J18.2 Hypostatic pneumonia, unspecified
0.665 0.335 0.000
Z42.0 Follow-up care involving plastic surgery of head and neck
0.665 0.335 0.000
M54.17 Radiculopathy (Lumbosacral region)
0.665 0.335 0.000
M62 Other disorders of muscle
0.665 0.335 0.000
R92 Abnormal findings on diagnostic imaging of breast
0.664 0.336 0.000
S70 Superficial injury of hip and thigh
0.664 0.336 0.000
C50.3 Lower-inner quadrant of breast
0.663 0.337 0.000
A07 Other protozoal intestinal diseases
0.663 0.337 0.000
A06 Amoebiasis
0.663 0.337 0.000
A05 Other bacterial foodborne intoxications
0.663 0.337 0.000
A03 Shigellosis
0.663 0.337 0.000
A02 Other Salmonella infections
0.663 0.337 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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