TreeWAS – Variant ID: rs115070742

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E03.9 Hypothyroidism, unspecified	0.000	0.000	1.000
J45.9 Asthma, unspecified	0.000	0.000	1.000
# Top node	0.000	0.000	1.000
K90.0 Coeliac disease	0.000	0.000	1.000
Chapter XI Diseases of the digestive system	0.000	0.000	1.000
E03 Other hypothyroidism	0.000	0.000	1.000
E00-E07 Disorders of thyroid gland	0.000	0.000	1.000
J45 Asthma	0.000	0.001	0.999
Chapter IV Endocrine, nutritional and metabolic diseases	0.000	0.001	0.999
K90 Intestinal malabsorption	0.000	0.001	0.999
Chapter X Diseases of the respiratory system	0.000	0.001	0.999
K90-K93 Other diseases of the digestive system	0.000	0.001	0.999
J40-J47 Chronic lower respiratory diseases	0.000	0.001	0.999
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.000	0.001	0.999
Chapter II Neoplasms	0.000	0.001	0.999
M06.9 Rheumatoid arthritis, unspecified	0.000	0.002	0.998
C43-C44 Melanoma and other malignant neoplasms of skin	0.000	0.003	0.997
C44 Other malignant neoplasms of skin	0.000	0.003	0.997
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.000	0.003	0.997
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.000	0.004	0.996
K20-K31 Diseases of oesophagus, stomach and duodenum	0.000	0.004	0.996
D60-D64 Aplastic and other anaemias	0.000	0.004	0.996
C44.3 Skin of other and unspecified parts of face	0.000	0.005	0.995
D64 Other anaemias	0.000	0.007	0.993
D64.9 Anaemia, unspecified	0.000	0.008	0.992
K29 Gastritis and duodenitis	0.000	0.011	0.989
K29.8 Duodenitis	0.000	0.014	0.986
K20 Oesophagitis	0.000	0.046	0.954
C44.7 Skin of lower limb, including hip	0.000	0.053	0.947
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.000	0.054	0.946
E05 Thyrotoxicosis [hyperthyroidism]	0.000	0.055	0.945
M06 Other rheumatoid arthritis	0.002	0.058	0.940
J44 Other chronic obstructive pulmonary disease	0.000	0.059	0.941
J00-J06 Acute upper respiratory infections	0.000	0.060	0.940
Chapter I Certain infectious and parasitic diseases	0.000	0.078	0.922
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.000	0.087	0.913
E05.9 Thyrotoxicosis, unspecified	0.000	0.103	0.897
B35-B49 Mycoses	0.000	0.104	0.896
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.000	0.118	0.882
B37 Candidiasis	0.000	0.121	0.879
J20-J22 Other acute lower respiratory infections	0.000	0.122	0.878
J46 Status asthmaticus	0.000	0.124	0.876
D37-D48 Neoplasms of uncertain or unknown behaviour	0.000	0.126	0.874
J44.8 Other specified chronic obstructive pulmonary disease	0.000	0.130	0.870
M05-M14 Inflammatory polyarthropathies	0.010	0.131	0.858
K29.4 Chronic atrophic gastritis	0.000	0.134	0.866
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.000	0.134	0.866
K22 Other diseases of oesophagus	0.000	0.136	0.864
C44.0 Skin of lip	0.000	0.137	0.863
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.000	0.140	0.860
J02 Acute pharyngitis	0.000	0.145	0.855
D00-D09 In situ neoplasms	0.000	0.146	0.854
B37.8 Candidiasis of other sites	0.000	0.146	0.854
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.000	0.148	0.852
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.000	0.158	0.842
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.023	0.160	0.816
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection	0.000	0.170	0.830
D70-D77 Other diseases of blood and blood-forming organs	0.000	0.177	0.823
K26 Duodenal ulcer	0.000	0.178	0.822
D69 Purpura and other haemorrhagic conditions	0.000	0.182	0.818
E20-E35 Disorders of other endocrine glands	0.000	0.183	0.817
E06 Thyroiditis	0.000	0.187	0.813
D06 Carcinoma in situ of cervix uteri	0.000	0.187	0.813
E50-E64 Other nutritional deficiencies	0.000	0.188	0.812
C44.4 Skin of scalp and neck	0.000	0.188	0.812
K70-K77 Diseases of liver	0.000	0.189	0.811
K22.2 Oesophageal obstruction	0.000	0.189	0.811
J90-J94 Other diseases of pleura	0.000	0.189	0.811
C82.9 Follicular non-Hodgkin's lymphoma, unspecified	0.000	0.192	0.808
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.000	0.192	0.808
J22 Unspecified acute lower respiratory infection	0.000	0.197	0.803
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.000	0.197	0.802
C51-C58 Malignant neoplasms of female genital organs	0.000	0.198	0.802
M06.0 Seronegative rheumatoid arthritis	0.001	0.198	0.801
K27 Peptic ulcer, site unspecified	0.000	0.201	0.799
B07 Viral warts	0.000	0.203	0.797
J02.9 Acute pharyngitis, unspecified	0.000	0.205	0.795
D62 Acute posthaemorrhagic anaemia	0.000	0.206	0.794
D06.9 Cervix, unspecified	0.000	0.216	0.784
D45 Polycythaemia vera	0.000	0.217	0.783
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.000	0.221	0.779
A50-A64 Infections with a predominantly sexual mode of transmission	0.000	0.222	0.778
D69.6 Thrombocytopenia, unspecified	0.000	0.226	0.774
K22.1 Ulcer of oesophagus	0.000	0.230	0.770
J90 Pleural effusion, not elsewhere classified	0.000	0.234	0.766
C73 Malignant neoplasm of thyroid gland	0.000	0.238	0.762
Chapter XII Diseases of the skin and subcutaneous tissue	0.000	0.239	0.761
J03 Acute tonsillitis	0.000	0.244	0.756
M80-M85 Disorders of bone density and structure	0.018	0.244	0.738
K29.5 Chronic gastritis, unspecified	0.000	0.247	0.753
K35-K38 Diseases of appendix	0.000	0.248	0.752
K29.1 Other acute gastritis	0.000	0.250	0.750
D80-D89 Certain disorders involving the immune mechanism	0.000	0.252	0.748
Z85.8 Personal history of malignant neoplasms of other organs and systems	0.000	0.252	0.748
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.000	0.252	0.748
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.253	0.747
D68 Other coagulation defects	0.000	0.256	0.744
E10-E14 Diabetes mellitus	0.000	0.262	0.738
C44.5 Skin of trunk	0.000	0.264	0.736
J44.9 Chronic obstructive pulmonary disease, unspecified	0.000	0.265	0.735
C81 Hodgkin's disease	0.000	0.265	0.735
K70 Alcoholic liver disease	0.000	0.266	0.734
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.000	0.268	0.732
D63 Anaemia in chronic diseases classified elsewhere	0.000	0.271	0.729
Chapter XXII Codes for special purposes	0.000	0.274	0.726
M81 Osteoporosis without pathological fracture	0.010	0.274	0.716
B37.0 Candidal stomatitis	0.000	0.275	0.725
C44.1 Skin of eyelid, including canthus	0.000	0.276	0.724
K50-K52 Noninfective enteritis and colitis	0.010	0.276	0.715
E07 Other disorders of thyroid	0.000	0.277	0.723
D75 Other diseases of blood and blood-forming organs	0.000	0.277	0.723
M05 Seropositive rheumatoid arthritis	0.006	0.279	0.715
K92 Other diseases of digestive system	0.000	0.280	0.720
C64-C68 Malignant neoplasms of urinary tract	0.000	0.281	0.719
Z85 Personal history of malignant neoplasm	0.000	0.281	0.719
C44.9 Malignant neoplasm of skin, unspecified	0.000	0.282	0.718
Chapter XVI Certain conditions originating in the perinatal period	0.000	0.283	0.717
E03.5 Myxoedema coma	0.000	0.283	0.717
E03.4 Atrophy of thyroid (acquired)	0.000	0.283	0.717
E03.3 Postinfectious hypothyroidism	0.000	0.283	0.717
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.000	0.283	0.717
E03.1 Congenital hypothyroidism without goitre	0.000	0.283	0.717
E03.0 Congenital hypothyroidism with diffuse goitre	0.000	0.283	0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.283	0.717
E00 Congenital iodine-deficiency syndrome	0.000	0.283	0.717
E02 Subclinical iodine-deficiency hypothyroidism	0.000	0.283	0.717
J45.8 Mixed asthma	0.000	0.283	0.717
J45.1 Nonallergic asthma	0.000	0.283	0.717
K90.8 Other intestinal malabsorption	0.000	0.283	0.716
K90.3 Pancreatic steatorrhoea	0.000	0.283	0.716
K90.2 Blind loop syndrome, not elsewhere classified	0.000	0.283	0.716
K90.1 Tropical sprue	0.000	0.283	0.716
K93 Disorders of other digestive organs in diseases classified elsewhere	0.000	0.283	0.716
J41 Simple and mucopurulent chronic bronchitis	0.000	0.284	0.716
J04 Acute laryngitis and tracheitis	0.000	0.284	0.716
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.000	0.284	0.716
C40-C41 Malignant neoplasms of bone and articular cartilage	0.000	0.284	0.716
M06.98 Rheumatoid arthritis, unspecified (Other)	0.000	0.284	0.716
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.000	0.284	0.716
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.000	0.284	0.716
C44.8 Overlapping lesion of skin	0.000	0.285	0.715
C85.9 Non-Hodgkin's lymphoma, unspecified type	0.000	0.285	0.715
K28 Gastrojejunal ulcer	0.000	0.286	0.714
K23 Disorders of oesophagus in diseases classified elsewhere	0.000	0.286	0.714
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.000	0.286	0.714
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.000	0.286	0.713
D64.8 Other specified anaemias	0.000	0.288	0.712
D64.4 Congenital dyserythropoietic anaemia	0.000	0.288	0.712
D64.3 Other sideroblastic anaemias	0.000	0.288	0.712
D64.2 Secondary sideroblastic anaemia due to drugs and toxins	0.000	0.288	0.712
D64.1 Secondary sideroblastic anaemia due to disease	0.000	0.288	0.712
D64.0 Hereditary sideroblastic anaemia	0.000	0.288	0.712
C53 Malignant neoplasm of cervix uteri	0.000	0.288	0.712
K26.9 Unspecified as acute or chronic, without haemorrhage or perforation	0.000	0.290	0.710
K29.9 Gastroduodenitis, unspecified	0.000	0.291	0.709
K29.2 Alcoholic gastritis	0.000	0.291	0.709
Z85.7 Personal history of other malignant neoplasms of lymphoid, haematopoietic and related tissues	0.000	0.291	0.709
D55-D59 Haemolytic anaemias	0.000	0.292	0.708
J01 Acute sinusitis	0.000	0.294	0.706
M81.9 Osteoporosis, unspecified	0.004	0.294	0.703
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.000	0.298	0.702
C90 Multiple myeloma and malignant plasma cell neoplasms	0.000	0.298	0.702
B90-B94 Sequelae of infectious and parasitic diseases	0.000	0.304	0.696
E55 Vitamin D deficiency	0.000	0.304	0.696
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.001	0.304	0.695
M81.99 Osteoporosis, unspecified (Site unspecified)	0.000	0.304	0.695
C91 Lymphoid leukaemia	0.000	0.308	0.692
J06 Acute upper respiratory infections of multiple and unspecified sites	0.000	0.311	0.689
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.000	0.313	0.687
K26.4 Chronic or unspecified with haemorrhage	0.000	0.314	0.686
J95-J99 Other diseases of the respiratory system	0.000	0.317	0.683
J45.0 Predominantly allergic asthma	0.000	0.319	0.681
L40-L45 Papulosquamous disorders	0.000	0.320	0.680
E11 Non-insulin-dependent diabetes mellitus	0.000	0.320	0.680
E06.3 Autoimmune thyroiditis	0.000	0.320	0.680
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.000	0.322	0.678
C95 Leukaemia of unspecified cell type	0.000	0.322	0.678
C94 Other leukaemias of specified cell type	0.000	0.322	0.678
C93 Monocytic leukaemia	0.000	0.322	0.678
C86 Other specified types of T/NK-cell lymphoma	0.000	0.322	0.678
C84 Peripheral and cutaneous T-cell lymphomas	0.000	0.322	0.678
E05.8 Other thyrotoxicosis	0.000	0.323	0.677
E05.5 Thyroid crisis or storm	0.000	0.323	0.677
E05.4 Thyrotoxicosis factitia	0.000	0.323	0.677
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.000	0.323	0.677
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.000	0.323	0.677
K70.9 Alcoholic liver disease, unspecified	0.000	0.323	0.677
M06.8 Other specified rheumatoid arthritis	0.002	0.325	0.674
M06.4 Inflammatory polyarthropathy	0.002	0.325	0.674
M06.3 Rheumatoid nodule	0.002	0.325	0.674
M06.2 Rheumatoid bursitis	0.002	0.325	0.674
M06.1 Adult-onset Still's disease	0.002	0.325	0.674
C92 Myeloid leukaemia	0.000	0.325	0.675
A63 Other predominantly sexually transmitted diseases, not elsewhere classified	0.000	0.326	0.674
J05 Acute obstructive laryngitis [croup] and epiglottitis	0.000	0.326	0.674
Z85.1 Personal history of malignant neoplasm of trachea, bronchus and lung	0.000	0.329	0.671
K29.3 Chronic superficial gastritis	0.000	0.331	0.669
E11.3 With ophthalmic complications	0.000	0.333	0.667
E21.0 Primary hyperparathyroidism	0.000	0.333	0.667
B35 Dermatophytosis	0.000	0.334	0.666
D46 Myelodysplastic syndromes	0.000	0.337	0.663
B20-B24 Human immunodeficiency virus [HIV] disease	0.000	0.337	0.662
D68.9 Coagulation defect, unspecified	0.000	0.338	0.662
B99-B99 Other infectious diseases	0.000	0.339	0.661
B85-B89 Pediculosis, acariasis and other infestations	0.000	0.339	0.661
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.000	0.339	0.661
A75-A79 Rickettsioses	0.000	0.339	0.661
A70-A74 Other diseases caused by chlamydiae	0.000	0.339	0.661
A65-A69 Other spirochaetal diseases	0.000	0.339	0.661
A20-A28 Certain zoonotic bacterial diseases	0.000	0.339	0.661
A15-A19 Tuberculosis	0.000	0.339	0.661
B37.9 Candidiasis, unspecified	0.000	0.340	0.660
E03.8 Other specified hypothyroidism	0.000	0.342	0.658
K51 Ulcerative colitis	0.004	0.343	0.653
K27.9 Unspecified as acute or chronic, without haemorrhage or perforation	0.000	0.343	0.657
J00 Acute nasopharyngitis [common cold]	0.000	0.344	0.656
B37.3 Candidiasis of vulva and vagina	0.000	0.344	0.656
D67 Hereditary factor IX deficiency	0.000	0.346	0.654
D66 Hereditary factor VIII deficiency	0.000	0.346	0.654
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.000	0.346	0.654
D05 Carcinoma in situ of breast	0.000	0.349	0.651
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.000	0.350	0.650
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.000	0.351	0.649
C53.9 Cervix uteri, unspecified	0.000	0.352	0.648
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.000	0.353	0.647
K22.8 Other specified diseases of oesophagus	0.000	0.353	0.647
K92.0 Haematemesis	0.000	0.354	0.646
D75.1 Secondary polycythaemia	0.000	0.355	0.645
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.000	0.355	0.644
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.000	0.355	0.644
E29 Testicular dysfunction	0.000	0.356	0.644
B48 Other mycoses, not elsewhere classified	0.000	0.357	0.643
B47 Mycetoma	0.000	0.357	0.643
B46 Zygomycosis	0.000	0.357	0.643
B45 Cryptococcosis	0.000	0.357	0.643
B43 Chromomycosis and phaeomycotic abscess	0.000	0.357	0.643
B42 Sporotrichosis	0.000	0.357	0.643
B41 Paracoccidioidomycosis	0.000	0.357	0.643
B40 Blastomycosis	0.000	0.357	0.643
B39 Histoplasmosis	0.000	0.357	0.643
B38 Coccidioidomycosis	0.000	0.357	0.643
B36 Other superficial mycoses	0.000	0.357	0.643
B49 Unspecified mycosis	0.000	0.357	0.643
C54 Malignant neoplasm of corpus uteri	0.000	0.358	0.642
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.000	0.359	0.641
C60-C63 Malignant neoplasms of male genital organs	0.000	0.359	0.641
C09 Malignant neoplasm of tonsil	0.000	0.360	0.640
C67 Malignant neoplasm of bladder	0.000	0.361	0.639
D47.2 Monoclonal gammopathy	0.000	0.361	0.639
M07 Psoriatic and enteropathic arthropathies	0.007	0.362	0.631
C83 Diffuse non-Hodgkin's lymphoma	0.000	0.363	0.637
D39 Neoplasm of uncertain or unknown behaviour of female genital organs	0.000	0.364	0.636
L57 Skin changes due to chronic exposure to nonionising radiation	0.000	0.365	0.635
C88 Malignant immunoproliferative diseases	0.000	0.366	0.633
K25 Gastric ulcer	0.000	0.367	0.633
C85.1 B-cell lymphoma, unspecified	0.000	0.369	0.631
B37.7 Candidal septicaemia	0.000	0.370	0.630
B37.6 Candidal endocarditis	0.000	0.370	0.630
B37.5 Candidal meningitis	0.000	0.370	0.630
B37.4 Candidiasis of other urogenital sites	0.000	0.370	0.630
B37.2 Candidiasis of skin and nail	0.000	0.370	0.630
B37.1 Pulmonary candidiasis	0.000	0.370	0.630
A80-A89 Viral infections of the central nervous system	0.000	0.370	0.630
J21 Acute bronchiolitis	0.000	0.370	0.630
L40 Psoriasis	0.000	0.371	0.629
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.000	0.371	0.628
K22.9 Disease of oesophagus, unspecified	0.000	0.372	0.628
K90.9 Intestinal malabsorption, unspecified	0.000	0.373	0.627
K31 Other diseases of stomach and duodenum	0.000	0.373	0.627
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands	0.000	0.373	0.626
D42 Neoplasm of uncertain or unknown behaviour of meninges	0.000	0.373	0.626
D40 Neoplasm of uncertain or unknown behaviour of male genital organs	0.000	0.373	0.626
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs	0.000	0.373	0.626
J03.9 Acute tonsillitis, unspecified	0.000	0.375	0.625
M14 Arthropathies in other diseases classified elsewhere	0.008	0.377	0.615
M12 Other specific arthropathies	0.008	0.377	0.615
M09 Juvenile arthritis in diseases classified elsewhere	0.008	0.377	0.615
M08 Juvenile arthritis	0.008	0.377	0.615
M91-M94 Chondropathies	0.015	0.378	0.607
D70 Agranulocytosis	0.000	0.378	0.622
C82.7 Other types of follicular non-Hodgkin's lymphoma	0.000	0.379	0.621
C82.6 Cutaneous follicle centre lymphoma	0.000	0.379	0.621
C82.5 Diffuse follicle centre lymphoma	0.000	0.379	0.621
C82.4 Follicular lymphoma grade IIIb	0.000	0.379	0.621
C82.3 Follicular lymphoma grade IIIa	0.000	0.379	0.621
C82.2 Large cell, follicular	0.000	0.379	0.621
C82.1 Mixed small cleaved and large cell, follicular	0.000	0.379	0.621
C82.0 Small cleaved cell, follicular	0.000	0.379	0.621
K22.3 Perforation of oesophagus	0.000	0.380	0.620
B25-B34 Other viral diseases	0.000	0.380	0.620
K51.9 Ulcerative colitis, unspecified	0.000	0.382	0.618
C75 Malignant neoplasm of other endocrine glands and related structures	0.000	0.383	0.617
C74 Malignant neoplasm of adrenal gland	0.000	0.383	0.617
B65-B83 Helminthiases	0.000	0.383	0.616
M05.9 Seropositive rheumatoid arthritis, unspecified	0.003	0.385	0.612
K29.0 Acute haemorrhagic gastritis	0.000	0.386	0.614
J02.8 Acute pharyngitis due to other specified organisms	0.000	0.387	0.613
J02.0 Streptococcal pharyngitis	0.000	0.387	0.613
L57.0 Actinic keratosis	0.000	0.387	0.613
E55.9 Vitamin D deficiency, unspecified	0.000	0.387	0.612
D02 Carcinoma in situ of middle ear and respiratory system	0.000	0.388	0.612
D01 Carcinoma in situ of other and unspecified digestive organs	0.000	0.388	0.612
D00 Carcinoma in situ of oral cavity, oesophagus and stomach	0.000	0.388	0.612
K65-K67 Diseases of peritoneum	0.000	0.389	0.611
E27 Other disorders of adrenal gland	0.000	0.392	0.608
M11 Other crystal arthropathies	0.007	0.392	0.601
K72 Hepatic failure, not elsewhere classified	0.000	0.392	0.607
B08 Other viral infections characterised by skin and mucous membrane lesions, not elsewhere classified	0.000	0.396	0.603
B06 Rubella [German measles]	0.000	0.396	0.603
B05 Measles	0.000	0.396	0.603
B01 Varicella [chickenpox]	0.000	0.396	0.603
B09 Unspecified viral infection characterised by skin and mucous membrane lesions	0.000	0.396	0.603
B04 Monkeypox	0.000	0.396	0.603
B03 Smallpox	0.000	0.396	0.603
B50-B64 Protozoal diseases	0.000	0.397	0.603
A63.0 Anogenital (venereal) warts	0.000	0.400	0.600
K22.4 Dyskinesia of oesophagus	0.000	0.401	0.599
D47.3 Essential (haemorrhagic) thrombocythaemia	0.000	0.403	0.597
C44.2 Skin of ear and external auricular canal	0.000	0.403	0.597
B44 Aspergillosis	0.000	0.405	0.595
D61 Other aplastic anaemias	0.000	0.405	0.595
D72 Other disorders of white blood cells	0.000	0.405	0.595
D41 Neoplasm of uncertain or unknown behaviour of urinary organs	0.000	0.406	0.594
K92.1 Melaena	0.000	0.406	0.594
D86 Sarcoidosis	0.000	0.407	0.593
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.000	0.407	0.593
B00 Herpesviral [herpes simplex] infections	0.000	0.409	0.591
D50-D53 Nutritional anaemias	0.000	0.409	0.590
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system	0.000	0.410	0.590
D74 Methaemoglobinaemia	0.000	0.410	0.590
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere	0.000	0.410	0.590
D71 Functional disorders of polymorphonuclear neutrophils	0.000	0.410	0.590
J20 Acute bronchitis	0.000	0.410	0.590
E23 Hypofunction and other disorders of pituitary gland	0.000	0.410	0.590
K26.6 Chronic or unspecified with both haemorrhage and perforation	0.000	0.411	0.589
K26.2 Acute with both haemorrhage and perforation	0.000	0.411	0.589
K26.1 Acute with perforation	0.000	0.411	0.589
K26.0 Acute with haemorrhage	0.000	0.411	0.589
D07 Carcinoma in situ of other and unspecified genital organs	0.000	0.412	0.588
K40-K46 Hernia	0.000	0.413	0.587
E21.3 Hyperparathyroidism, unspecified	0.000	0.413	0.587
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.001	0.413	0.586
D69.9 Haemorrhagic condition, unspecified	0.000	0.414	0.586
D69.8 Other specified haemorrhagic conditions	0.000	0.414	0.586
D69.4 Other primary thrombocytopenia	0.000	0.414	0.586
D69.2 Other nonthrombocytopenic purpura	0.000	0.414	0.586
D69.1 Qualitative platelet defects	0.000	0.414	0.586
D69.0 Allergic purpura	0.000	0.414	0.586
E35 Disorders of endocrine glands in diseases classified elsewhere	0.000	0.414	0.586
E32 Diseases of thymus	0.000	0.414	0.586
E31 Polyglandular dysfunction	0.000	0.414	0.586
E30 Disorders of puberty, not elsewhere classified	0.000	0.414	0.586
E26 Hyperaldosteronism	0.000	0.414	0.586
E25 Adrenogenital disorders	0.000	0.414	0.586
E20 Hypoparathyroidism	0.000	0.414	0.586
C67.9 Bladder, unspecified	0.000	0.415	0.585
E53 Deficiency of other B group vitamins	0.000	0.416	0.584
C81.9 Hodgkin's disease, unspecified	0.000	0.416	0.584
E06.9 Thyroiditis, unspecified	0.000	0.417	0.583
E06.5 Other chronic thyroiditis	0.000	0.417	0.583
E06.4 Drug-induced thyroiditis	0.000	0.417	0.583
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.000	0.417	0.583
E06.1 Subacute thyroiditis	0.000	0.417	0.583
E06.0 Acute thyroiditis	0.000	0.417	0.583
D06.7 Other parts of cervix	0.000	0.417	0.583
D06.1 Exocervix	0.000	0.417	0.583
D06.0 Endocervix	0.000	0.417	0.583
E64 Sequelae of malnutrition and other nutritional deficiencies	0.000	0.418	0.582
E63 Other nutritional deficiencies	0.000	0.418	0.582
E56 Other vitamin deficiencies	0.000	0.418	0.582
E51 Thiamine deficiency	0.000	0.418	0.582
E50 Vitamin A deficiency	0.000	0.418	0.582
E60 Dietary zinc deficiency	0.000	0.418	0.582
E59 Dietary selenium deficiency	0.000	0.418	0.582
E58 Dietary calcium deficiency	0.000	0.418	0.582
E54 Ascorbic acid deficiency	0.000	0.418	0.582
E52 Niacin deficiency [pellagra]	0.000	0.418	0.582
K77 Liver disorders in diseases classified elsewhere	0.000	0.418	0.582
K73 Chronic hepatitis, not elsewhere classified	0.000	0.418	0.582
K71 Toxic liver disease	0.000	0.418	0.582
J94 Other pleural conditions	0.000	0.419	0.581
J95 Postprocedural respiratory disorders, not elsewhere classified	0.000	0.419	0.581
L40.9 Psoriasis, unspecified	0.000	0.420	0.580
C85.2 Mediastinal (thymic) large B-cell lymphoma	0.000	0.421	0.579
C85.0 Lymphosarcoma	0.000	0.421	0.579
C02 Malignant neoplasm of other and unspecified parts of tongue	0.000	0.421	0.579
K51.2 Ulcerative (chronic) proctitis	0.002	0.423	0.576
E40-E46 Malnutrition	0.000	0.423	0.576
C57 Malignant neoplasm of other and unspecified female genital organs	0.000	0.425	0.575
C58 Malignant neoplasm of placenta	0.000	0.425	0.575
C55 Malignant neoplasm of uterus, part unspecified	0.000	0.425	0.575
C52 Malignant neoplasm of vagina	0.000	0.425	0.575
M06.08 Seronegative rheumatoid arthritis (Other)	0.001	0.425	0.574
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.001	0.425	0.574
M06.06 Seronegative rheumatoid arthritis (Lower leg)	0.001	0.425	0.574
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.001	0.425	0.574
M06.04 Seronegative rheumatoid arthritis (Hand)	0.001	0.425	0.574
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.001	0.425	0.574
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.001	0.425	0.574
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.001	0.425	0.574
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system	0.000	0.425	0.574
C51 Malignant neoplasm of vulva	0.000	0.426	0.574
M00-M03 Infectious arthropathies	0.018	0.427	0.555
K27.7 Chronic without haemorrhage or perforation	0.000	0.427	0.573
K27.6 Chronic or unspecified with both haemorrhage and perforation	0.000	0.427	0.573
K27.5 Chronic or unspecified with perforation	0.000	0.427	0.573
K27.4 Chronic or unspecified with haemorrhage	0.000	0.427	0.573
K27.3 Acute without haemorrhage or perforation	0.000	0.427	0.573
K27.2 Acute with both haemorrhage and perforation	0.000	0.427	0.573
K27.1 Acute with perforation	0.000	0.427	0.573
K27.0 Acute with haemorrhage	0.000	0.427	0.573
E11.4 With neurological complications	0.000	0.428	0.572
D09 Carcinoma in situ of other and unspecified sites	0.000	0.429	0.571
D69.3 Idiopathic thrombocytopenic purpura	0.000	0.429	0.571
A30-A49 Other bacterial diseases	0.000	0.433	0.567
K22.5 Diverticulum of oesophagus, acquired	0.000	0.434	0.566
M60-M63 Disorders of muscles	0.018	0.434	0.548
K37 Unspecified appendicitis	0.000	0.435	0.565
E07.9 Disorder of thyroid, unspecified	0.000	0.435	0.565
C90.0 Multiple myeloma	0.000	0.435	0.565
K44 Diaphragmatic hernia	0.000	0.435	0.565
M81.98 Osteoporosis, unspecified (Other)	0.002	0.435	0.563
E34 Other endocrine disorders	0.000	0.437	0.563
M10 Gout	0.006	0.437	0.557
J60-J70 Lung diseases due to external agents	0.000	0.438	0.562
D75.8 Other specified diseases of blood and blood-forming organs	0.000	0.440	0.559
L80-L99 Other disorders of the skin and subcutaneous tissue	0.000	0.441	0.559
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx	0.000	0.441	0.558
C13 Malignant neoplasm of hypopharynx	0.000	0.441	0.558
C11 Malignant neoplasm of nasopharynx	0.000	0.441	0.558
C10 Malignant neoplasm of oropharynx	0.000	0.441	0.558
C08 Malignant neoplasm of other and unspecified major salivary glands	0.000	0.441	0.558
C06 Malignant neoplasm of other and unspecified parts of mouth	0.000	0.441	0.558
C05 Malignant neoplasm of palate	0.000	0.441	0.558
C04 Malignant neoplasm of floor of mouth	0.000	0.441	0.558
C03 Malignant neoplasm of gum	0.000	0.441	0.558
C00 Malignant neoplasm of lip	0.000	0.441	0.558
C12 Malignant neoplasm of pyriform sinus	0.000	0.441	0.558
C07 Malignant neoplasm of parotid gland	0.000	0.441	0.558
K35 Acute appendicitis	0.000	0.442	0.558
A60 Anogenital herpesviral [herpes simplex] infections	0.000	0.442	0.558
A59 Trichomoniasis	0.000	0.442	0.558
A56 Other sexually transmitted chlamydial diseases	0.000	0.442	0.558
A54 Gonococcal infection	0.000	0.442	0.558
A53 Other and unspecified syphilis	0.000	0.442	0.558
A52 Late syphilis	0.000	0.442	0.558
A51 Early syphilis	0.000	0.442	0.558
A50 Congenital syphilis	0.000	0.442	0.558
A64 Unspecified sexually transmitted disease	0.000	0.442	0.558
A58 Granuloma inguinale	0.000	0.442	0.558
A57 Chancroid	0.000	0.442	0.558
A55 Chlamydial lymphogranuloma (venereum)	0.000	0.442	0.558
J04.0 Acute laryngitis	0.000	0.444	0.556
K75 Other inflammatory liver diseases	0.000	0.447	0.553
K26.5 Chronic or unspecified with perforation	0.000	0.449	0.551
K70.4 Alcoholic hepatic failure	0.000	0.449	0.551
K44.9 Diaphragmatic hernia without obstruction or gangrene	0.000	0.451	0.549
B02 Zoster [herpes zoster]	0.000	0.452	0.548
Z85.4 Personal history of malignant neoplasm of genital organs	0.000	0.454	0.546
L10-L14 Bullous disorders	0.000	0.455	0.545
K51.8 Other ulcerative colitis	0.002	0.456	0.542
E61 Deficiency of other nutrient elements	0.000	0.456	0.544
K25.9 Unspecified as acute or chronic, without haemorrhage or perforation	0.000	0.457	0.543
E24 Cushing's syndrome	0.000	0.457	0.543
K22.0 Achalasia of cardia	0.000	0.457	0.543
J03.8 Acute tonsillitis due to other specified organisms	0.000	0.458	0.542
J03.0 Streptococcal tonsillitis	0.000	0.458	0.542
D63.8 Anaemia in other chronic diseases classified elsewhere	0.000	0.458	0.542
M83 Adult osteomalacia	0.013	0.458	0.529
M82 Osteoporosis in diseases classified elsewhere	0.013	0.458	0.529
C09.9 Tonsil, unspecified	0.000	0.460	0.540
J91 Pleural effusion in conditions classified elsewhere	0.000	0.460	0.540
D68.5 Primary Thrombophilia	0.000	0.460	0.540
J01.9 Acute sinusitis, unspecified	0.000	0.461	0.539
K36 Other appendicitis	0.000	0.461	0.539
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.000	0.462	0.538
D84 Other immunodeficiencies	0.000	0.463	0.537
D83 Common variable immunodeficiency	0.000	0.463	0.537
D82 Immunodeficiency associated with other major defects	0.000	0.463	0.537
D81 Combined immunodeficiencies	0.000	0.463	0.537
D80 Immunodeficiency with predominantly antibody defects	0.000	0.463	0.537
K22.6 Gastro-oesophageal laceration-haemorrhage syndrome	0.000	0.464	0.536
D47.9 Neoplasm of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue, unspecified	0.000	0.464	0.536
D47.7 Other specified neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.000	0.464	0.536
D47.5 Chronic eosinophilic leukaemia [hypereosinophilic syndrome]	0.000	0.464	0.536
D47.4 Osteomyelofibrosis	0.000	0.464	0.536
D47.0 Histiocytic and mast cell tumours of uncertain and unknown behaviour	0.000	0.464	0.536
D68.6 Other Thrombophilia	0.000	0.466	0.533
D68.4 Acquired coagulation factor deficiency	0.000	0.466	0.533
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.000	0.466	0.533
D68.1 Hereditary factor XI deficiency	0.000	0.466	0.533
D68.0 Von Willebrand's disease	0.000	0.466	0.533
B91 Sequelae of poliomyelitis	0.000	0.467	0.533
E22 Hyperfunction of pituitary gland	0.000	0.467	0.533
B15-B19 Viral hepatitis	0.000	0.468	0.532
K70.3 Alcoholic cirrhosis of liver	0.000	0.468	0.532
L82 Seborrhoeic keratosis	0.000	0.468	0.532
K91 Postprocedural disorders of digestive system, not elsewhere classified	0.000	0.469	0.531
K38 Other diseases of appendix	0.000	0.470	0.530
E12 Malnutrition-related diabetes mellitus	0.000	0.470	0.529

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations