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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs115190431
log Bayes Factor = 20.4755
Chromosome 2   position 42,468,603  (GRCh37) Explore rs115190431 on Ensembl!
Variant rs115190431 is part of Cluster X0194

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Chapter X Diseases of the respiratory system
1.000 0.000 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.999 0.001 0.000
I30-I52 Other forms of heart disease
0.998 0.002 0.000
I20-I25 Ischaemic heart diseases
0.998 0.002 0.000
I25 Chronic ischaemic heart disease
0.995 0.005 0.000
R30-R39 Symptoms and signs involving the urinary system
0.995 0.005 0.000
Chapter XX External causes of morbidity and mortality
0.995 0.005 0.000
J30-J39 Other diseases of upper respiratory tract
0.993 0.007 0.000
I50 Heart failure
0.989 0.011 0.000
Chapter XIV Diseases of the genitourinary system
0.987 0.013 0.000
I25.2 Old myocardial infarction
0.983 0.017 0.000
M50-M54 Other dorsopathies
0.981 0.019 0.000
R18 Ascites
0.980 0.020 0.000
R10 Abdominal and pelvic pain
0.973 0.027 0.000
Chapter VIII Diseases of the ear and mastoid process
0.973 0.027 0.000
Chapter V Mental and behavioural disorders
0.970 0.030 0.000
Chapter I Certain infectious and parasitic diseases
0.969 0.031 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.967 0.033 0.000
M15-M19 Arthrosis
0.967 0.033 0.000
I50.1 Left ventricular failure
0.965 0.035 0.000
M20-M25 Other joint disorders
0.965 0.035 0.000
Chapter VII Diseases of the eye and adnexa
0.960 0.040 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.956 0.044 0.000
J20-J22 Other acute lower respiratory infections
0.955 0.045 0.000
J40-J47 Chronic lower respiratory diseases
0.953 0.047 0.000
R10.3 Pain localised to other parts of lower abdomen
0.949 0.051 0.000
R32 Unspecified urinary incontinence
0.947 0.053 0.000
R35 Polyuria
0.944 0.056 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.944 0.056 0.000
M51 Other intervertebral disk disorders
0.942 0.058 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.939 0.061 0.000
M17 Gonarthrosis [arthrosis of knee]
0.938 0.062 0.000
Chapter VI Diseases of the nervous system
0.937 0.063 0.000
Chapter XXI Factors influencing health status and contact with health services
0.931 0.069 0.000
M45-M49 Spondylopathies
0.930 0.070 0.000
J22 Unspecified acute lower respiratory infection
0.923 0.077 0.000
A00-A09 Intestinal infectious diseases
0.917 0.083 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.916 0.084 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.911 0.089 0.000
M18 Arthrosis of first carpometacarpal joint
0.906 0.094 0.000
M25 Other joint disorders, not elsewhere classified
0.905 0.095 0.000
R21 Rash and other nonspecific skin eruption
0.903 0.097 0.000
F41 Other anxiety disorders
0.903 0.097 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.902 0.098 0.000
M17.9 Gonarthrosis, unspecified
0.896 0.104 0.000
I50.9 Heart failure, unspecified
0.894 0.106 0.000
M23 Internal derangement of knee
0.891 0.109 0.000
N83 Noninflammatory disorders of ovary, Fallopian tube and broad ligament
0.890 0.110 0.000
J34 Other disorders of nose and nasal sinuses
0.887 0.113 0.000
R12 Heartburn
0.885 0.115 0.000
W00-W19 Falls
0.885 0.115 0.000
M05-M14 Inflammatory polyarthropathies
0.884 0.116 0.000
M51.2 Other specified intervertebral disk displacement
0.883 0.117 0.000
J33 Nasal polyp
0.878 0.122 0.000
H65-H75 Diseases of middle ear and mastoid
0.873 0.127 0.000
R14 Flatulence and related conditions
0.871 0.129 0.000
M54 Dorsalgia
0.869 0.131 0.000
H25-H28 Disorders of lens
0.868 0.132 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.868 0.132 0.000
Y83.4 Other reconstructive surgery
0.867 0.133 0.000
J47 Bronchiectasis
0.866 0.134 0.000
H60-H62 Diseases of external ear
0.865 0.135 0.000
R31 Unspecified haematuria
0.865 0.135 0.000
N60-N64 Disorders of breast
0.864 0.136 0.000
I44 Atrioventricular and left bundle-branch block
0.864 0.136 0.000
R15 Faecal incontinence
0.864 0.136 0.000
J44 Other chronic obstructive pulmonary disease
0.856 0.144 0.000
I47 Paroxysmal tachycardia
0.856 0.144 0.000
G90-G99 Other disorders of the nervous system
0.855 0.145 0.000
F41.2 Mixed anxiety and depressive disorder
0.855 0.145 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.854 0.146 0.000
M65-M68 Disorders of synovium and tendon
0.854 0.146 0.000
Z30 Contraceptive management
0.853 0.147 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.847 0.153 0.000
J32 Chronic sinusitis
0.846 0.154 0.000
R33 Retention of urine
0.843 0.157 0.000
J95-J99 Other diseases of the respiratory system
0.842 0.158 0.000
M47 Spondylosis
0.842 0.158 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.839 0.161 0.000
M86-M90 Other osteopathies
0.837 0.163 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.837 0.163 0.000
I34 Nonrheumatic mitral valve disorders
0.830 0.170 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.829 0.171 0.000
J33.9 Nasal polyp, unspecified
0.829 0.171 0.000
H25 Senile cataract
0.828 0.172 0.000
I24 Other acute ischaemic heart diseases
0.827 0.173 0.000
Z30.2 Sterilisation
0.827 0.173 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.827 0.173 0.000
N10-N16 Renal tubulo-interstitial diseases
0.827 0.173 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.826 0.174 0.000
M18.9 Arthrosis of first carpometacarpal joint, unspecified
0.820 0.180 0.000
M54.5 Low back pain
0.819 0.181 0.000
A04 Other bacterial intestinal infections
0.816 0.184 0.000
A09 Diarrhoea and gastro-enteritis of presumed infectious origin
0.815 0.185 0.000
M25.7 Osteophyte
0.815 0.185 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.813 0.186 0.000
R17 Unspecified jaundice
0.808 0.192 0.000
W19 Unspecified fall
0.806 0.194 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.805 0.195 0.000
J90-J94 Other diseases of pleura
0.803 0.197 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.795 0.205 0.000
H25.8 Other senile cataract
0.793 0.207 0.000
H90-H95 Other disorders of ear
0.793 0.207 0.000
Z30.1 Insertion of (intra-uterine) contraceptive device
0.792 0.208 0.000
M10 Gout
0.792 0.208 0.000
N80 Endometriosis
0.792 0.208 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.790 0.210 0.000
I22 Subsequent myocardial infarction
0.789 0.211 0.000
N83.2 Other and unspecified ovarian cysts
0.789 0.211 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.787 0.213 0.000
Y83.8 Other surgical procedures
0.786 0.214 0.000
I20 Angina pectoris
0.785 0.215 0.000
Y40 Systemic antibiotics
0.784 0.216 0.000
J39 Other diseases of upper respiratory tract
0.781 0.219 0.000
R10.4 Other and unspecified abdominal pain
0.780 0.220 0.000
A30-A49 Other bacterial diseases
0.780 0.220 0.000
N83.8 Other noninflammatory disorders of ovary, Fallopian tube and broad ligament
0.779 0.221 0.000
I38 Endocarditis, valve unspecified
0.779 0.221 0.000
M18.1 Other primary arthrosis of first carpometacarpal joint
0.779 0.221 0.000
R10.2 Pelvic and perineal pain
0.778 0.222 0.000
I44.1 Atrioventricular block, second degree
0.777 0.223 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.776 0.224 0.000
J34.3 Hypertrophy of nasal turbinates
0.774 0.226 0.000
I42 Cardiomyopathy
0.771 0.229 0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.770 0.230 0.000
M47.9 Spondylosis, unspecified
0.770 0.230 0.000
H72 Perforation of tympanic membrane
0.770 0.230 0.000
H80-H83 Diseases of inner ear
0.769 0.231 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.769 0.231 0.000
M51.8 Other specified intervertebral disk disorders
0.768 0.232 0.000
G20-G26 Extrapyramidal and movement disorders
0.768 0.232 0.000
N83.0 Follicular cyst of ovary
0.768 0.232 0.000
M17.0 Primary gonarthrosis, bilateral
0.766 0.234 0.000
N25-N29 Other disorders of kidney and ureter
0.766 0.234 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.765 0.235 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.765 0.235 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.764 0.235 0.000
I50.0 Congestive heart failure
0.764 0.236 0.000
F45 Somatoform disorders
0.763 0.237 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.759 0.241 0.000
H55-H59 Other disorders of eye and adnexa
0.759 0.241 0.000
R23 Other skin changes
0.759 0.241 0.000
N17-N19 Renal failure
0.759 0.241 0.000
M23.23 Derangement of meniscus due to old tear or injury (Medial collateral ligament or Other and unspecified medial meniscus)
0.758 0.242 0.000
I26 Pulmonary embolism
0.758 0.242 0.000
H61 Other disorders of external ear
0.757 0.243 0.000
N64 Other disorders of breast
0.756 0.244 0.000
R10.0 Acute abdomen
0.756 0.244 0.000
I34.0 Mitral (valve) insufficiency
0.755 0.245 0.000
J35 Chronic diseases of tonsils and adenoids
0.755 0.245 0.000
R04 Haemorrhage from respiratory passages
0.754 0.246 0.000
M23.8 Other internal derangements of knee
0.754 0.246 0.000
Y83.2 Surgical operation with anastomosis, bypass or graft
0.754 0.246 0.000
M80-M85 Disorders of bone density and structure
0.751 0.249 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.750 0.250 0.000
N60 Benign mammary dysplasia
0.749 0.251 0.000
M22 Disorders of patella
0.749 0.251 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.748 0.252 0.000
H30-H36 Disorders of choroid and retina
0.748 0.252 0.000
R30 Pain associated with micturition
0.747 0.253 0.000
F42 Obsessive-compulsive disorder
0.747 0.253 0.000
M51.0 Lumbar and other intervertebral disk disorders with myelopathy
0.747 0.253 0.000
Y43 Primarily systemic agents
0.746 0.254 0.000
R05 Cough
0.745 0.255 0.000
F41.9 Anxiety disorder, unspecified
0.744 0.256 0.000
R01 Cardiac murmurs and other cardiac sounds
0.744 0.256 0.000
N99-N99 Other disorders of the genitourinary system
0.744 0.256 0.000
M65 Synovitis and tenosynovitis
0.743 0.257 0.000
A09.9 Gastroenteritis and colitis of unspecified origin
0.743 0.257 0.000
M50 Cervical disk disorders
0.742 0.258 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.741 0.259 0.000
J40 Bronchitis, not specified as acute or chronic
0.740 0.260 0.000
N40-N51 Diseases of male genital organs
0.739 0.261 0.000
W20-W49 Exposure to inanimate mechanical forces
0.739 0.261 0.000
G95 Other diseases of spinal cord
0.738 0.262 0.000
M17.1 Other primary gonarthrosis
0.738 0.262 0.000
E20-E35 Disorders of other endocrine glands
0.736 0.264 0.000
M25.8 Other specified joint disorders
0.736 0.264 0.000
B25-B34 Other viral diseases
0.736 0.264 0.000
I49 Other cardiac arrhythmias
0.734 0.266 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.733 0.267 0.000
J30 Vasomotor and allergic rhinitis
0.733 0.267 0.000
M54.59 Low back pain (Site unspecified)
0.733 0.267 0.000
J36 Peritonsillar abscess
0.733 0.267 0.000
E10-E14 Diabetes mellitus
0.733 0.267 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.732 0.268 0.000
M48 Other spondylopathies
0.732 0.268 0.000
H43-H45 Disorders of vitreous body and globe
0.731 0.269 0.000
Y83.5 Amputation of limb(s)
0.731 0.269 0.000
X60-X84 Intentional self-harm
0.731 0.269 0.000
M46 Other inflammatory spondylopathies
0.730 0.270 0.000
J98 Other respiratory disorders
0.728 0.272 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.728 0.272 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.726 0.274 0.000
M10.9 Gout, unspecified
0.726 0.274 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.725 0.275 0.000
Chapter XI Diseases of the digestive system
0.724 0.276 0.000
N95 Menopausal and other perimenopausal disorders
0.722 0.278 0.000
J60-J70 Lung diseases due to external agents
0.721 0.279 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.721 0.279 0.000
Y44 Agents primarily affecting blood constituents
0.721 0.279 0.000
I46 Cardiac arrest
0.720 0.280 0.000
Y52 Agents primarily affecting the cardiovascular system
0.719 0.281 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.718 0.282 0.000
I44.0 Atrioventricular block, first degree
0.718 0.282 0.000
R04.2 Haemoptysis
0.718 0.282 0.000
N83.3 Acquired atrophy of ovary and Fallopian tube
0.717 0.282 0.000
J00-J06 Acute upper respiratory infections
0.717 0.283 0.000
H71 Cholesteatoma of middle ear
0.717 0.283 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.717 0.283 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
R20 Disturbances of skin sensation
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
M91-M94 Chondropathies
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.717 0.283 0.000
I60-I69 Cerebrovascular diseases
0.716 0.284 0.000
I52 Other heart disorders in diseases classified elsewhere
0.716 0.284 0.000
I48 Atrial fibrillation and flutter
0.716 0.284 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.716 0.284 0.000
I41 Myocarditis in diseases classified elsewhere
0.716 0.284 0.000
I40 Acute myocarditis
0.716 0.284 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.716 0.284 0.000
I37 Pulmonary valve disorders
0.716 0.284 0.000
I36 Nonrheumatic tricuspid valve disorders
0.716 0.284 0.000
I33 Acute and subacute endocarditis
0.716 0.284 0.000
I32 Pericarditis in diseases classified elsewhere
0.716 0.284 0.000
I30 Acute pericarditis
0.716 0.284 0.000
Y86 Sequelae of other accidents
0.716 0.284 0.000
I23 Certain current complications following acute myocardial infarction
0.716 0.284 0.000
N00-N08 Glomerular diseases
0.715 0.285 0.000
Chapter XXII Codes for special purposes
0.715 0.285 0.000
A04.7 Enterocolitis due to Clostridium difficile
0.715 0.285 0.000
M25.76 Osteophyte (Lower leg)
0.715 0.285 0.000
J32.9 Chronic sinusitis, unspecified
0.714 0.286 0.000
I25.6 Silent myocardial ischaemia
0.713 0.287 0.000
I25.5 Ischaemic cardiomyopathy
0.713 0.287 0.000
I25.4 Coronary artery aneurysm
0.713 0.287 0.000
I25.3 Aneurysm of heart
0.713 0.287 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.713 0.287 0.000
R36 Urethral discharge
0.713 0.287 0.000
R34 Anuria and oliguria
0.713 0.287 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.713 0.287 0.000
Y35-Y36 Legal intervention and operations of war
0.713 0.287 0.000
Y10-Y34 Event of undetermined intent
0.713 0.287 0.000
Y00-Y09 Assault
0.713 0.287 0.000
X85-X99 Assault
0.713 0.287 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.713 0.287 0.000
X50-X57 Overexertion, travel and privation
0.713 0.287 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.713 0.287 0.000
X30-X39 Exposure to forces of nature
0.713 0.287 0.000
X20-X29 Contact with venomous animals and plants
0.713 0.287 0.000
X10-X19 Contact with heat and hot substances
0.713 0.287 0.000
X00-X09 Exposure to smoke, fire and flames
0.713 0.287 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.713 0.287 0.000
W75-W84 Other accidental threats to breathing
0.713 0.287 0.000
W65-W74 Accidental drowning and submersion
0.713 0.287 0.000
W50-W64 Exposure to animate mechanical forces
0.713 0.287 0.000
V98-V99 Other and unspecified transport accidents
0.713 0.287 0.000
V95-V97 Air and space transport accidents
0.713 0.287 0.000
V90-V94 Water transport accidents
0.713 0.287 0.000
V80-V89 Other land transport accidents
0.713 0.287 0.000
V70-V79 Bus occupant injured in transport accident
0.713 0.287 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.713 0.287 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.713 0.287 0.000
V40-V49 Car occupant injured in transport accident
0.713 0.287 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.713 0.287 0.000
V20-V29 Motorcycle rider injured in transport accident
0.713 0.287 0.000
V10-V19 Pedal cyclist injured in transport accident
0.713 0.287 0.000
V01-V09 Pedestrian injured in transport accident
0.713 0.287 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.712 0.288 0.000
R16 Hepatomegaly and splenomegaly, not elsewhere classified
0.712 0.288 0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue
0.712 0.288 0.000
J37 Chronic laryngitis and laryngotracheitis
0.712 0.288 0.000
J09-J18 Influenza and pneumonia
0.711 0.289 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.711 0.289 0.000
M54.56 Low back pain (Lumbar region)
0.710 0.290 0.000
B15-B19 Viral hepatitis
0.709 0.291 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.709 0.291 0.000
J34.2 Deviated nasal septum
0.708 0.292 0.000
M25.5 Pain in joint
0.706 0.294 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.705 0.295 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.705 0.295 0.000
M89 Other disorders of bone
0.705 0.295 0.000
N89 Other noninflammatory disorders of vagina
0.705 0.295 0.000
F40 Phobic anxiety disorders
0.704 0.296 0.000
I35 Nonrheumatic aortic valve disorders
0.703 0.297 0.000
M53 Other dorsopathies, not elsewhere classified
0.703 0.297 0.000
B95-B98 Bacterial, viral and other infectious agents
0.703 0.297 0.000
N80.3 Endometriosis of pelvic peritoneum
0.702 0.298 0.000
I47.2 Ventricular tachycardia
0.700 0.300 0.000
F30-F39 Mood [affective] disorders
0.699 0.301 0.000
J42 Unspecified chronic bronchitis
0.699 0.301 0.000
G70-G73 Diseases of myoneural junction and muscle
0.698 0.302 0.000
K20-K31 Diseases of oesophagus, stomach and duodenum
0.698 0.302 0.000
R79 Other abnormal findings of blood chemistry
0.697 0.303 0.000
M40-M43 Deforming dorsopathies
0.697 0.303 0.000
I47.1 Supraventricular tachycardia
0.697 0.303 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.697 0.303 0.000
F99-F99 Unspecified mental disorder
0.695 0.305 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.695 0.305 0.000
F80-F89 Disorders of psychological development
0.695 0.305 0.000
F70-F79 Mental retardation
0.695 0.305 0.000
F60-F69 Disorders of adult personality and behaviour
0.695 0.305 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.695 0.305 0.000
B99-B99 Other infectious diseases
0.695 0.305 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.695 0.305 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.695 0.305 0.000
B65-B83 Helminthiases
0.695 0.305 0.000
B50-B64 Protozoal diseases
0.695 0.305 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.695 0.305 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.695 0.305 0.000
A80-A89 Viral infections of the central nervous system
0.695 0.305 0.000
A75-A79 Rickettsioses
0.695 0.305 0.000
A70-A74 Other diseases caused by chlamydiae
0.695 0.305 0.000
A65-A69 Other spirochaetal diseases
0.695 0.305 0.000
A20-A28 Certain zoonotic bacterial diseases
0.695 0.305 0.000
A15-A19 Tuberculosis
0.695 0.305 0.000
G30-G32 Other degenerative diseases of the nervous system
0.694 0.305 0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.694 0.306 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.694 0.306 0.000
H52 Disorders of refraction and accommodation
0.694 0.306 0.000
M15 Polyarthrosis
0.693 0.307 0.000
B35-B49 Mycoses
0.693 0.307 0.000
N84 Polyp of female genital tract
0.693 0.307 0.000
W19.4 Street and highway
0.692 0.308 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.692 0.308 0.000
M34 Systemic sclerosis
0.692 0.308 0.000
M33 Dermatopolymyositis
0.692 0.308 0.000
M32 Systemic lupus erythematosus
0.692 0.308 0.000
M30 Polyarteritis nodosa and related conditions
0.692 0.308 0.000
M21 Other acquired deformities of limbs
0.692 0.308 0.000
J84 Other interstitial pulmonary diseases
0.690 0.310 0.000
M35 Other systemic involvement of connective tissue
0.690 0.310 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.688 0.312 0.000
H10-H13 Disorders of conjunctiva
0.688 0.312 0.000
H60 Otitis externa
0.688 0.312 0.000
N93 Other abnormal uterine and vaginal bleeding
0.687 0.313 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.686 0.314 0.000
N86 Erosion and ectropion of cervix uteri
0.685 0.315 0.000
J21 Acute bronchiolitis
0.685 0.315 0.000
J20 Acute bronchitis
0.685 0.315 0.000
I45 Other conduction disorders
0.684 0.316 0.000
J41 Simple and mucopurulent chronic bronchitis
0.684 0.316 0.000
J46 Status asthmaticus
0.684 0.316 0.000
M23.25 Derangement of meniscus due to old tear or injury (Posterior horn of lateral meniscus)
0.683 0.316 0.000
W19.9 Unspecified place
0.680 0.320 0.000
N92 Excessive, frequent and irregular menstruation
0.679 0.321 0.000
N64.5 Other signs and symptoms in breast
0.679 0.321 0.000
F48 Other neurotic disorders
0.677 0.323 0.000
F44 Dissociative [conversion] disorders
0.677 0.323 0.000
F43 Reaction to severe stress, and adjustment disorders
0.677 0.323 0.000
M31 Other necrotising vasculopathies
0.677 0.323 0.000
I31 Other diseases of pericardium
0.676 0.323 0.000
H25.9 Senile cataract, unspecified
0.676 0.324 0.000
E11 Non-insulin-dependent diabetes mellitus
0.676 0.324 0.000
M51.3 Other specified intervertebral disk degeneration
0.675 0.325 0.000
M51.1 Lumbar and other intervertebral disk disorders with radiculopathy
0.675 0.325 0.000
M51.9 Intervertebral disk disorder, unspecified
0.675 0.325 0.000
M51.4 Schmorl's nodes
0.675 0.325 0.000
J90 Pleural effusion, not elsewhere classified
0.675 0.325 0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.674 0.326 0.000
M17.5 Other secondary gonarthrosis
0.673 0.327 0.000
M17.4 Other secondary gonarthrosis, bilateral
0.673 0.327 0.000
M17.3 Other posttraumatic gonarthrosis
0.673 0.327 0.000
M17.2 Posttraumatic gonarthrosis, bilateral
0.673 0.327 0.000
I05-I09 Chronic rheumatic heart diseases
0.672 0.327 0.000
J43 Emphysema
0.672 0.327 0.000
M25.4 Effusion of joint
0.672 0.328 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.672 0.328 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.671 0.329 0.000
J32.8 Other chronic sinusitis
0.670 0.330 0.000
M47.96 Spondylosis, unspecified (Lumbar region)
0.668 0.332 0.000
A08 Viral and other specified intestinal infections
0.668 0.332 0.000
H72.9 Perforation of tympanic membrane, unspecified
0.667 0.333 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.667 0.333 0.000
M49 Spondylopathies in diseases classified elsewhere
0.667 0.333 0.000
M45 Ankylosing spondylitis
0.667 0.333 0.000
I51 Complications and ill-defined descriptions of heart disease
0.666 0.334 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.666 0.334 0.000
R01.1 Cardiac murmur, unspecified
0.666 0.334 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.665 0.335 0.000
H25.0 Senile incipient cataract
0.665 0.335 0.000
M13 Other arthritis
0.665 0.335 0.000
N30-N39 Other diseases of urinary system
0.664 0.336 0.000
M47.99 Spondylosis, unspecified (Site unspecified)
0.662 0.337 0.000
H73 Other disorders of tympanic membrane
0.661 0.338 0.000
G93 Other disorders of brain
0.661 0.339 0.000
J38.0 Paralysis of vocal cords and larynx
0.661 0.339 0.000
N42 Other disorders of prostate
0.658 0.342 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.658 0.342 0.000
K29 Gastritis and duodenitis
0.658 0.342 0.000
I42.0 Dilated cardiomyopathy
0.657 0.343 0.000
A07 Other protozoal intestinal diseases
0.657 0.343 0.000
A06 Amoebiasis
0.657 0.343 0.000
A05 Other bacterial foodborne intoxications
0.657 0.343 0.000
A03 Shigellosis
0.657 0.343 0.000
A02 Other Salmonella infections
0.657 0.343 0.000
A01 Typhoid and paratyphoid fevers
0.657 0.343 0.000
A00 Cholera
0.657 0.343 0.000
Y59 Other and unspecified vaccines and biological substances
0.657 0.343 0.000
Y58 Bacterial vaccines
0.657 0.343 0.000
Y57 Other and unspecified drugs and medicaments
0.657 0.343 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.657 0.343 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.657 0.343 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.657 0.343 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.657 0.343 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.657 0.343 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.657 0.343 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.657 0.343 0.000
Y48 Anaesthetics and therapeutic gases
0.657 0.343 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.657 0.343 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.657 0.343 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.657 0.343 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.657 0.343 0.000
J38.7 Other diseases of larynx
0.656 0.344 0.000
M24 Other specific joint derangements
0.655 0.345 0.000
M23.20 Derangement of meniscus due to old tear or injury (Multiple sites)
0.654 0.346 0.000
N95.2 Postmenopausal atrophic vaginitis
0.654 0.346 0.000
J34.8 Other specified disorders of nose and nasal sinuses
0.654 0.346 0.000
N98 Complications associated with artificial fertilisation
0.653 0.347 0.000
N91 Absent, scanty and rare menstruation
0.653 0.347 0.000
N82 Fistulae involving female genital tract
0.653 0.347 0.000
N96 Habitual aborter
0.653 0.347 0.000
D50-D53 Nutritional anaemias
0.653 0.347 0.000
Y40.0 Penicillins
0.652 0.348 0.000
M05 Seropositive rheumatoid arthritis
0.652 0.348 0.000
H00 Hordeolum and chalazion
0.652 0.348 0.000
F41.0 Panic disorder [episodic paroxysmal anxiety]
0.651 0.349 0.000
R06 Abnormalities of breathing
0.651 0.349 0.000
E00-E07 Disorders of thyroid gland
0.650 0.350 0.000
M18.5 Other secondary arthrosis of first carpometacarpal joint
0.650 0.350 0.000
M18.4 Other secondary arthrosis of first carpometacarpal joints, bilateral
0.650 0.350 0.000
M18.3 Other posttraumatic arthrosis of first carpometacarpal joint
0.650 0.350 0.000
M18.2 Posttraumatic arthrosis of first carpometacarpal joints, bilateral
0.650 0.350 0.000
M18.0 Primary arthrosis of first carpometacarpal joints, bilateral
0.650 0.350 0.000
M23.81 Other internal derangements of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.649 0.350 0.000
M25.9 Joint disorder, unspecified
0.649 0.351 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.649 0.351 0.000
M25.3 Other instability of joint
0.649 0.351 0.000
M25.2 Flail joint
0.649 0.351 0.000
M25.1 Fistula of joint
0.649 0.351 0.000
M25.0 Haemarthrosis
0.649 0.351 0.000
H61.0 Perichondritis of external ear
0.649 0.351 0.000
F41.8 Other specified anxiety disorders
0.647 0.353 0.000
F41.3 Other mixed anxiety disorders
0.647 0.353 0.000
F41.1 Generalised anxiety disorder
0.647 0.353 0.000
Y83.9 Surgical procedure, unspecified
0.647 0.353 0.000
Y83.0 Surgical operation with transplant of whole organ
0.647 0.353 0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances
0.644 0.356 0.000
J38.3 Other diseases of vocal cords
0.643 0.357 0.000
K29.6 Other gastritis
0.643 0.357 0.000
N62 Hypertrophy of breast
0.642 0.358 0.000
M10.99 Gout, unspecified (Site unspecified)
0.642 0.358 0.000
M54.4 Lumbago with sciatica
0.641 0.358 0.000
H01 Other inflammation of eyelid
0.641 0.359 0.000
N80.1 Endometriosis of ovary
0.640 0.360 0.000
A04.8 Other specified bacterial intestinal infections
0.639 0.361 0.000
M23.9 Internal derangement of knee, unspecified
0.639 0.361 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.639 0.361 0.000
M23.5 Chronic instability of knee
0.639 0.361 0.000
M23.4 Loose body in knee
0.639 0.361 0.000
M23.1 Discoid meniscus (congenital)
0.639 0.361 0.000
M23.0 Cystic meniscus
0.639 0.361 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.639 0.361 0.000
N83.9 Noninflammatory disorder of ovary, Fallopian tube and broad ligament, unspecified
0.638 0.362 0.000
N83.7 Haematoma of broad ligament
0.638 0.362 0.000
N83.6 Haematosalpinx
0.638 0.362 0.000
N83.5 Torsion of ovary, ovarian pedicle and Fallopian tube
0.638 0.362 0.000
N83.4 Prolapse and hernia of ovary and Fallopian tube
0.638 0.362 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.638 0.362 0.000
K31 Other diseases of stomach and duodenum
0.637 0.363 0.000
K26 Duodenal ulcer
0.636 0.364 0.000
J34.1 Cyst and mucocele of nose and nasal sinus
0.636 0.364 0.000
J34.0 Abscess, furuncle and carbuncle of nose
0.636 0.364 0.000
N20-N23 Urolithiasis
0.636 0.364 0.000
W18 Other fall on same level
0.634 0.366 0.000
W17 Other fall from one level to another
0.634 0.366 0.000
W16 Diving or jumping into water causing injury other than drowning or submersion
0.634 0.366 0.000
W15 Fall from cliff
0.634 0.366 0.000
W14 Fall from tree
0.634 0.366 0.000
W13 Fall from, out of or through building or structure
0.634 0.366 0.000
W12 Fall on and from scaffolding
0.634 0.366 0.000
W11 Fall on and from ladder
0.634 0.366 0.000
W10 Fall on and from stairs and steps
0.634 0.366 0.000
W09 Fall involving playground equipment
0.634 0.366 0.000
W08 Fall involving other furniture
0.634 0.366 0.000
W07 Fall involving chair
0.634 0.366 0.000
W06 Fall involving bed
0.634 0.366 0.000
W05 Fall involving wheelchair
0.634 0.366 0.000
W04 Fall while being carried or supported by other persons
0.634 0.366 0.000
W03 Other fall on same level due to collision with, or pushing by, another person
0.634 0.366 0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards
0.634 0.366 0.000
W01 Fall on same level from slipping, tripping and stumbling
0.634 0.366 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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