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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs115252368
log Bayes Factor = 16.3421
Chromosome 5   position 67,715,716  (GRCh37) Explore rs115252368 on Ensembl!
Variant rs115252368 is part of Cluster X0070

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter I Certain infectious and parasitic diseases
1.000 0.000 0.000
R50-R69 General symptoms and signs
1.000 0.000 0.000
B95-B98 Bacterial, viral and other infectious agents
0.999 0.001 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.998 0.002 0.000
M20-M25 Other joint disorders
0.998 0.002 0.000
M15-M19 Arthrosis
0.993 0.007 0.000
A30-A49 Other bacterial diseases
0.987 0.013 0.000
M25 Other joint disorders, not elsewhere classified
0.981 0.019 0.000
R51 Headache
0.978 0.022 0.000
M17 Gonarthrosis [arthrosis of knee]
0.976 0.024 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.976 0.024 0.000
R50 Fever of unknown origin
0.971 0.029 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.970 0.030 0.000
R56 Convulsions, not elsewhere classified
0.969 0.031 0.000
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters
0.968 0.032 0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters
0.967 0.033 0.000
Chapter V Mental and behavioural disorders
0.967 0.033 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.965 0.035 0.000
Chapter VI Diseases of the nervous system
0.963 0.037 0.000
M17.9 Gonarthrosis, unspecified
0.960 0.040 0.000
A41 Other septicaemia
0.960 0.040 0.000
R63 Symptoms and signs concerning food and fluid intake
0.956 0.044 0.000
R50.9 Fever, unspecified
0.951 0.049 0.000
R47-R49 Symptoms and signs involving speech and voice
0.951 0.049 0.000
Chapter VII Diseases of the eye and adnexa
0.951 0.049 0.000
R56.8 Other and unspecified convulsions
0.948 0.052 0.000
A00-A09 Intestinal infectious diseases
0.941 0.059 0.000
M23 Internal derangement of knee
0.941 0.059 0.000
G40-G47 Episodic and paroxysmal disorders
0.941 0.059 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.939 0.061 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.933 0.067 0.000
G47 Sleep disorders
0.932 0.068 0.000
A41.9 Septicaemia, unspecified
0.930 0.070 0.000
Chapter X Diseases of the respiratory system
0.925 0.075 0.000
M50-M54 Other dorsopathies
0.920 0.080 0.000
T81 Complications of procedures, not elsewhere classified
0.920 0.080 0.000
R05 Cough
0.916 0.084 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.915 0.085 0.000
M65-M68 Disorders of synovium and tendon
0.909 0.091 0.000
Chapter VIII Diseases of the ear and mastoid process
0.905 0.095 0.000
Q60-Q64 Congenital malformations of the urinary system
0.905 0.095 0.000
M16 Coxarthrosis [arthrosis of hip]
0.903 0.097 0.000
R63.0 Anorexia
0.901 0.099 0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters
0.899 0.101 0.000
M25.5 Pain in joint
0.899 0.101 0.000
A04 Other bacterial intestinal infections
0.899 0.101 0.000
R47 Speech disturbances, not elsewhere classified
0.898 0.102 0.000
Chapter XX External causes of morbidity and mortality
0.897 0.103 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.894 0.106 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.891 0.109 0.000
A49 Bacterial infection of unspecified site
0.888 0.112 0.000
R06 Abnormalities of breathing
0.883 0.117 0.000
R53 Malaise and fatigue
0.878 0.122 0.000
Chapter XXII Codes for special purposes
0.876 0.124 0.000
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters
0.875 0.125 0.000
J40-J47 Chronic lower respiratory diseases
0.875 0.125 0.000
M16.9 Coxarthrosis, unspecified
0.873 0.127 0.000
R91 Abnormal findings on diagnostic imaging of lung
0.872 0.128 0.000
A04.8 Other specified bacterial intestinal infections
0.871 0.129 0.000
G47.9 Sleep disorder, unspecified
0.868 0.132 0.000
G47.3 Sleep apnoea
0.863 0.137 0.000
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified
0.860 0.140 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.858 0.142 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.855 0.145 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.855 0.145 0.000
Q61 Cystic kidney disease
0.850 0.150 0.000
S20-S29 Injuries to the thorax
0.848 0.152 0.000
R47.0 Dysphasia and aphasia
0.841 0.159 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.840 0.160 0.000
R06.5 Mouth breathing
0.840 0.160 0.000
M25.7 Osteophyte
0.839 0.161 0.000
T79-T79 Certain early complications of trauma
0.838 0.162 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.836 0.164 0.000
R63.4 Abnormal weight loss
0.836 0.164 0.000
T66-T78 Other and unspecified effects of external causes
0.832 0.167 0.000
M19 Other arthrosis
0.831 0.169 0.000
T81.3 Disruption of operation wound, not elsewhere classified
0.831 0.169 0.000
M65 Synovitis and tenosynovitis
0.830 0.170 0.000
M22 Disorders of patella
0.829 0.171 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.828 0.172 0.000
R12 Heartburn
0.826 0.174 0.000
M25.4 Effusion of joint
0.825 0.175 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.825 0.175 0.000
G47.8 Other sleep disorders
0.823 0.176 0.000
R26 Abnormalities of gait and mobility
0.820 0.180 0.000
H30-H36 Disorders of choroid and retina
0.818 0.182 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.817 0.183 0.000
H02 Other disorders of eyelid
0.816 0.184 0.000
B15-B19 Viral hepatitis
0.814 0.186 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.813 0.187 0.000
R07 Pain in throat and chest
0.810 0.190 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.810 0.190 0.000
J95-J99 Other diseases of the respiratory system
0.809 0.191 0.000
G81 Hemiplegia
0.808 0.192 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.808 0.192 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.806 0.194 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.803 0.197 0.000
M50 Cervical disk disorders
0.803 0.197 0.000
M25.0 Haemarthrosis
0.803 0.197 0.000
M25.56 Pain in joint (Lower leg)
0.802 0.198 0.000
R52 Pain, not elsewhere classified
0.797 0.203 0.000
R03 Abnormal blood-pressure reading, without diagnosis
0.796 0.204 0.000
H50 Other strabismus
0.791 0.209 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.790 0.210 0.000
M23.20 Derangement of meniscus due to old tear or injury (Multiple sites)
0.786 0.214 0.000
R50.8 Other specified fever
0.785 0.215 0.000
M86-M90 Other osteopathies
0.782 0.218 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.780 0.220 0.000
G40 Epilepsy
0.779 0.221 0.000
M35 Other systemic involvement of connective tissue
0.779 0.221 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.777 0.223 0.000
A49.0 Staphylococcal infection, unspecified
0.777 0.223 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.774 0.226 0.000
M24 Other specific joint derangements
0.774 0.226 0.000
M91-M94 Chondropathies
0.774 0.226 0.000
J44 Other chronic obstructive pulmonary disease
0.774 0.226 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.773 0.227 0.000
R49 Voice disturbances
0.773 0.227 0.000
F30-F39 Mood [affective] disorders
0.771 0.229 0.000
M23.9 Internal derangement of knee, unspecified
0.770 0.230 0.000
M54 Dorsalgia
0.770 0.230 0.000
M17.0 Primary gonarthrosis, bilateral
0.769 0.231 0.000
A41.1 Septicaemia due to other specified staphylococcus
0.768 0.232 0.000
J47 Bronchiectasis
0.768 0.232 0.000
Q00-Q07 Congenital malformations of the nervous system
0.767 0.233 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.767 0.233 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.767 0.233 0.000
F05 Delirium, not induced by alcohol and other psychoactive substances
0.765 0.235 0.000
M23.3 Other meniscus derangements
0.765 0.235 0.000
M00-M03 Infectious arthropathies
0.763 0.237 0.000
R68 Other general symptoms and signs
0.760 0.240 0.000
S60-S69 Injuries to the wrist and hand
0.759 0.241 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.759 0.241 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.758 0.242 0.000
R07.3 Other chest pain
0.758 0.242 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.757 0.243 0.000
A41.5 Septicaemia due to other Gram-negative organisms
0.756 0.244 0.000
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure
0.755 0.245 0.000
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified
0.753 0.247 0.000
J86 Pyothorax
0.752 0.248 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.751 0.249 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.750 0.250 0.000
H80-H83 Diseases of inner ear
0.747 0.253 0.000
F45 Somatoform disorders
0.747 0.253 0.000
G81.9 Hemiplegia, unspecified
0.747 0.253 0.000
G82 Paraplegia and tetraplegia
0.747 0.253 0.000
Q61.2 Polycystic kidney, adult type
0.746 0.254 0.000
H60-H62 Diseases of external ear
0.746 0.254 0.000
R72 Abnormality of white blood cells, not elsewhere classified
0.742 0.258 0.000
F01 Vascular dementia
0.741 0.259 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.740 0.260 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.740 0.260 0.000
M25.54 Pain in joint (Hand)
0.738 0.262 0.000
A08 Viral and other specified intestinal infections
0.738 0.262 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.738 0.262 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.736 0.263 0.000
R26.8 Other and unspecified abnormalities of gait and mobility
0.736 0.264 0.000
R60 Oedema, not elsewhere classified
0.735 0.265 0.000
R03.0 Elevated blood-pressure reading, without diagnosis of hypertension
0.733 0.267 0.000
M40-M43 Deforming dorsopathies
0.732 0.268 0.000
T78 Adverse effects, not elsewhere classified
0.730 0.270 0.000
A49.9 Bacterial infection, unspecified
0.729 0.271 0.000
J42 Unspecified chronic bronchitis
0.729 0.271 0.000
G30-G32 Other degenerative diseases of the nervous system
0.728 0.272 0.000
J46 Status asthmaticus
0.727 0.273 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.726 0.274 0.000
M25.57 Pain in joint (Ankle and foot)
0.725 0.275 0.000
Q61.0 Congenital single renal cyst
0.724 0.276 0.000
H50.1 Divergent concomitant strabismus
0.722 0.278 0.000
S40-S49 Injuries to the shoulder and upper arm
0.722 0.278 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.721 0.279 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.721 0.279 0.000
M65.3 Trigger finger
0.720 0.280 0.000
R16 Hepatomegaly and splenomegaly, not elsewhere classified
0.720 0.280 0.000
W20-W49 Exposure to inanimate mechanical forces
0.720 0.280 0.000
T81.7 Vascular complications following a procedure, not elsewhere classified
0.720 0.280 0.000
Chapter IX Diseases of the circulatory system
0.719 0.281 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.719 0.281 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.719 0.281 0.000
H55-H59 Other disorders of eye and adnexa
0.718 0.282 0.000
B99-B99 Other infectious diseases
0.717 0.283 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.717 0.283 0.000
B65-B83 Helminthiases
0.717 0.283 0.000
B50-B64 Protozoal diseases
0.717 0.283 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.717 0.283 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.717 0.283 0.000
A80-A89 Viral infections of the central nervous system
0.717 0.283 0.000
A75-A79 Rickettsioses
0.717 0.283 0.000
A70-A74 Other diseases caused by chlamydiae
0.717 0.283 0.000
A65-A69 Other spirochaetal diseases
0.717 0.283 0.000
A20-A28 Certain zoonotic bacterial diseases
0.717 0.283 0.000
A15-A19 Tuberculosis
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
R06.2 Wheezing
0.717 0.283 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.717 0.283 0.000
R62 Lack of expected normal physiological development
0.717 0.283 0.000
R57 Shock, not elsewhere classified
0.717 0.283 0.000
R64 Cachexia
0.717 0.283 0.000
R58 Haemorrhage, not elsewhere classified
0.717 0.283 0.000
H53-H54 Visual disturbances and blindness
0.717 0.283 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.717 0.283 0.000
B96.7 Clostridium perfringens [C. perfringens] as the cause of diseases classified to other chapters
0.715 0.284 0.000
B96.6 Bacillus fragilis [B. fragilis] as the cause of diseases classified to other chapters
0.715 0.284 0.000
B96.0 Mycoplasma pneumoniae [M. pneumoniae] as the cause of diseases classified to other chapters
0.715 0.284 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.715 0.285 0.000
M34 Systemic sclerosis
0.715 0.285 0.000
M33 Dermatopolymyositis
0.715 0.285 0.000
M32 Systemic lupus erythematosus
0.715 0.285 0.000
M30 Polyarteritis nodosa and related conditions
0.715 0.285 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.715 0.285 0.000
R47.1 Dysarthria and anarthria
0.715 0.285 0.000
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters
0.715 0.285 0.000
T81.8 Other complications of procedures, not elsewhere classified
0.714 0.286 0.000
H02.8 Other specified disorders of eyelid
0.714 0.286 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.712 0.288 0.000
M15 Polyarthrosis
0.712 0.288 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.711 0.289 0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease
0.711 0.289 0.000
J09-J18 Influenza and pneumonia
0.710 0.289 0.000
A48 Other bacterial diseases, not elsewhere classified
0.707 0.292 0.000
A44 Bartonellosis
0.707 0.292 0.000
A43 Nocardiosis
0.707 0.292 0.000
A42 Actinomycosis
0.707 0.292 0.000
A40 Streptococcal septicaemia
0.707 0.292 0.000
A39 Meningococcal infection
0.707 0.292 0.000
A37 Whooping cough
0.707 0.292 0.000
A36 Diphtheria
0.707 0.292 0.000
A32 Listeriosis
0.707 0.292 0.000
A31 Infection due to other mycobacteria
0.707 0.292 0.000
A30 Leprosy [Hansen's disease]
0.707 0.292 0.000
A46 Erysipelas
0.707 0.292 0.000
A38 Scarlet fever
0.707 0.292 0.000
A35 Other tetanus
0.707 0.292 0.000
A34 Obstetrical tetanus
0.707 0.292 0.000
A33 Tetanus neonatorum
0.707 0.292 0.000
H90-H95 Other disorders of ear
0.707 0.293 0.000
F99-F99 Unspecified mental disorder
0.707 0.293 0.000
S80-S89 Injuries to the knee and lower leg
0.707 0.293 0.000
H02.1 Ectropion of eyelid
0.704 0.296 0.000
M25.9 Joint disorder, unspecified
0.703 0.297 0.000
M25.8 Other specified joint disorders
0.703 0.297 0.000
M25.3 Other instability of joint
0.703 0.297 0.000
M25.2 Flail joint
0.703 0.297 0.000
M25.1 Fistula of joint
0.703 0.297 0.000
Q60 Renal agenesis and other reduction defects of kidney
0.703 0.297 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.702 0.298 0.000
M31 Other necrotising vasculopathies
0.702 0.298 0.000
J86.9 Pyothorax without fistula
0.701 0.299 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.700 0.300 0.000
M17.5 Other secondary gonarthrosis
0.700 0.300 0.000
M17.4 Other secondary gonarthrosis, bilateral
0.700 0.300 0.000
M17.3 Other posttraumatic gonarthrosis
0.700 0.300 0.000
M17.2 Posttraumatic gonarthrosis, bilateral
0.700 0.300 0.000
F40 Phobic anxiety disorders
0.700 0.300 0.000
T33-T35 Frostbite
0.699 0.300 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.699 0.300 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.699 0.300 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.699 0.300 0.000
T00-T07 Injuries involving multiple body regions
0.699 0.300 0.000
S10-S19 Injuries to the neck
0.699 0.300 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.699 0.301 0.000
M51 Other intervertebral disk disorders
0.699 0.301 0.000
M19.9 Arthrosis, unspecified
0.698 0.302 0.000
M21 Other acquired deformities of limbs
0.698 0.302 0.000
J90-J94 Other diseases of pleura
0.698 0.302 0.000
R50.2 Drug-induced fever
0.696 0.303 0.000
R50.1 Persistent fever
0.696 0.303 0.000
R11 Nausea and vomiting
0.696 0.304 0.000
M67 Other disorders of synovium and tendon
0.695 0.305 0.000
R56.0 Febrile convulsions
0.695 0.305 0.000
R29.6 Tendency to fall, not elsewhere classified
0.695 0.305 0.000
F80-F89 Disorders of psychological development
0.694 0.306 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.694 0.306 0.000
G44 Other headache syndromes
0.693 0.306 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.693 0.307 0.000
F70-F79 Mental retardation
0.693 0.307 0.000
F60-F69 Disorders of adult personality and behaviour
0.693 0.307 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.693 0.307 0.000
R01 Cardiac murmurs and other cardiac sounds
0.693 0.307 0.000
H02.4 Ptosis of eyelid
0.693 0.307 0.000
S90-S99 Injuries to the ankle and foot
0.692 0.308 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.692 0.308 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.692 0.308 0.000
Q80-Q89 Other congenital malformations
0.692 0.308 0.000
Q50-Q56 Congenital malformations of genital organs
0.692 0.308 0.000
Q35-Q37 Cleft lip and cleft palate
0.692 0.308 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.692 0.308 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.692 0.308 0.000
R06.4 Hyperventilation
0.692 0.308 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.692 0.308 0.000
M16.7 Other secondary coxarthrosis
0.691 0.309 0.000
J60-J70 Lung diseases due to external agents
0.691 0.309 0.000
M23.24 Derangement of meniscus due to old tear or injury (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.691 0.309 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.691 0.309 0.000
M22.4 Chondromalacia patellae
0.690 0.310 0.000
G47.0 Disorders of initiating and maintaining sleep [insomnias]
0.689 0.311 0.000
M25.75 Osteophyte (Pelvic region and thigh)
0.689 0.311 0.000
U80 Agent resistant to penicillin and related antibiotics
0.688 0.311 0.000
A41.4 Septicaemia due to anaerobes
0.688 0.312 0.000
A41.3 Septicaemia due to Haemophilus influenzae
0.688 0.312 0.000
A41.2 Septicaemia due to unspecified staphylococcus
0.688 0.312 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.688 0.312 0.000
M23.8 Other internal derangements of knee
0.688 0.312 0.000
G70-G73 Diseases of myoneural junction and muscle
0.688 0.312 0.000
M25.46 Effusion of joint (Lower leg)
0.686 0.313 0.000
R63.6 Insufficient intake of food and water due to self neglect
0.685 0.315 0.000
R63.5 Abnormal weight gain
0.685 0.315 0.000
R63.3 Feeding difficulties and mismanagement
0.685 0.315 0.000
R63.2 Polyphagia
0.685 0.315 0.000
R63.1 Polydipsia
0.685 0.315 0.000
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters
0.683 0.317 0.000
A04.7 Enterocolitis due to Clostridium difficile
0.682 0.318 0.000
R48 Dyslexia and other symbolic dysfunctions, not elsewhere classified
0.682 0.318 0.000
S70-S79 Injuries to the hip and thigh
0.681 0.319 0.000
B18 Chronic viral hepatitis
0.681 0.319 0.000
M54.9 Dorsalgia, unspecified
0.681 0.319 0.000
Y40 Systemic antibiotics
0.680 0.320 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.680 0.320 0.000
T86 Failure and rejection of transplanted organs and tissues
0.680 0.320 0.000
B02 Zoster [herpes zoster]
0.679 0.321 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.679 0.321 0.000
R06.1 Stridor
0.678 0.321 0.000
B91 Sequelae of poliomyelitis
0.678 0.322 0.000
M25.59 Pain in joint (Site unspecified)
0.678 0.322 0.000
E00-E07 Disorders of thyroid gland
0.678 0.322 0.000
Q61.3 Polycystic kidney, unspecified
0.678 0.322 0.000
M19.1 Posttraumatic arthrosis of other joints
0.677 0.323 0.000
M17.1 Other primary gonarthrosis
0.677 0.323 0.000
H00 Hordeolum and chalazion
0.676 0.324 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.676 0.324 0.000
M25.06 Haemarthrosis (Lower leg)
0.675 0.325 0.000
H02.3 Blepharochalasis
0.675 0.325 0.000
H65-H75 Diseases of middle ear and mastoid
0.675 0.325 0.000
A07 Other protozoal intestinal diseases
0.675 0.325 0.000
A06 Amoebiasis
0.675 0.325 0.000
A05 Other bacterial foodborne intoxications
0.675 0.325 0.000
A03 Shigellosis
0.675 0.325 0.000
A02 Other Salmonella infections
0.675 0.325 0.000
A01 Typhoid and paratyphoid fevers
0.675 0.325 0.000
A00 Cholera
0.675 0.325 0.000
H10-H13 Disorders of conjunctiva
0.675 0.325 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.675 0.325 0.000
M23.5 Chronic instability of knee
0.675 0.325 0.000
M23.4 Loose body in knee
0.675 0.325 0.000
M23.1 Discoid meniscus (congenital)
0.675 0.325 0.000
M23.0 Cystic meniscus
0.675 0.325 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.674 0.326 0.000
G41 Status epilepticus
0.674 0.326 0.000
F05.9 Delirium, unspecified
0.674 0.326 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.674 0.326 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.673 0.326 0.000
T87 Complications peculiar to reattachment and amputation
0.673 0.327 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.673 0.327 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.673 0.327 0.000
V20-V29 Motorcycle rider injured in transport accident
0.673 0.327 0.000
H35 Other retinal disorders
0.672 0.328 0.000
S29 Other and unspecified injuries of thorax
0.671 0.329 0.000
M23.29 Derangement of meniscus due to old tear or injury (Unspecified ligament or Unspecified meniscus)
0.670 0.330 0.000
A41.8 Other specified septicaemia
0.670 0.330 0.000
H33 Retinal detachments and breaks
0.670 0.330 0.000
R92 Abnormal findings on diagnostic imaging of breast
0.669 0.331 0.000
M25.50 Pain in joint (Multiple sites)
0.669 0.331 0.000
G20-G26 Extrapyramidal and movement disorders
0.668 0.331 0.000
G47.4 Narcolepsy and cataplexy
0.668 0.332 0.000
G47.2 Disorders of the sleep-wake schedule
0.668 0.332 0.000
G47.1 Disorders of excessive somnolence [hypersomnias]
0.668 0.332 0.000
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters
0.668 0.332 0.000
M65.9 Synovitis and tenosynovitis, unspecified
0.668 0.332 0.000
F45.8 Other somatoform disorders
0.668 0.332 0.000
M05-M14 Inflammatory polyarthropathies
0.668 0.332 0.000
F42 Obsessive-compulsive disorder
0.667 0.333 0.000
M20 Acquired deformities of fingers and toes
0.667 0.333 0.000
H43-H45 Disorders of vitreous body and globe
0.666 0.334 0.000
M50.2 Other cervical disk displacement
0.666 0.334 0.000
M80-M85 Disorders of bone density and structure
0.665 0.335 0.000
M50.1 Cervical disk disorder with radiculopathy
0.664 0.336 0.000
R47.8 Other and unspecified speech disturbances
0.664 0.336 0.000
R61 Hyperhidrosis
0.662 0.338 0.000
M23.25 Derangement of meniscus due to old tear or injury (Posterior horn of lateral meniscus)
0.662 0.338 0.000
R52.2 Other chronic pain
0.661 0.339 0.000
M35.3 Polymyalgia rheumatica
0.661 0.339 0.000
M53 Other dorsopathies, not elsewhere classified
0.660 0.340 0.000
T81.9 Unspecified complication of procedure
0.659 0.340 0.000
T81.6 Acute reaction to foreign substance accidentally left during a procedure
0.659 0.340 0.000
T81.1 Shock during or resulting from a procedure, not elsewhere classified
0.659 0.340 0.000
J40 Bronchitis, not specified as acute or chronic
0.658 0.342 0.000
A41.0 Septicaemia due to Staphylococcus aureus
0.656 0.344 0.000
M25.77 Osteophyte (Ankle and foot)
0.656 0.344 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.655 0.345 0.000
M65.4 Radial styloid tenosynovitis [de Quervain]
0.653 0.347 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.652 0.348 0.000
M54.1 Radiculopathy
0.652 0.348 0.000
G40.9 Epilepsy, unspecified
0.652 0.348 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.651 0.349 0.000
M66 Spontaneous rupture of synovium and tendon
0.651 0.349 0.000
T85.2 Mechanical complication of intraocular lens
0.651 0.349 0.000
J98 Other respiratory disorders
0.650 0.349 0.000
F31 Bipolar affective disorder
0.650 0.350 0.000
M25.71 Osteophyte (Shoulder region)
0.649 0.351 0.000
T85.9 Unspecified complication of internal prosthetic device, implant and graft
0.649 0.351 0.000
Q64 Other congenital malformations of urinary system
0.649 0.351 0.000
Q63 Other congenital malformations of kidney
0.649 0.351 0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter
0.649 0.351 0.000
E50-E64 Other nutritional deficiencies
0.649 0.351 0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.648 0.352 0.000
M23.99 Internal derangement of knee, unspecified (Unspecified ligament or Unspecified meniscus)
0.648 0.352 0.000
M16.6 Other secondary coxarthrosis, bilateral
0.648 0.352 0.000
M16.5 Other posttraumatic coxarthrosis
0.648 0.352 0.000
M16.4 Posttraumatic coxarthrosis, bilateral
0.648 0.352 0.000
M16.3 Other dysplastic coxarthrosis
0.648 0.352 0.000
M16.2 Coxarthrosis resulting from dysplasia, bilateral
0.648 0.352 0.000
R07.1 Chest pain on breathing
0.647 0.353 0.000
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
0.647 0.353 0.000
M45-M49 Spondylopathies
0.647 0.353 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.645 0.355 0.000
M22.2 Patellofemoral disorders
0.645 0.355 0.000
R49.0 Dysphonia
0.645 0.355 0.000
F03 Unspecified dementia
0.645 0.355 0.000
X60-X84 Intentional self-harm
0.644 0.355 0.000
M25.58 Pain in joint (Other)
0.644 0.356 0.000
M25.52 Pain in joint (Upper arm)
0.644 0.356 0.000
A04.9 Bacterial intestinal infection, unspecified
0.644 0.356 0.000
A04.6 Enteritis due to Yersinia enterocolitica
0.644 0.356 0.000
A04.4 Other intestinal Escherichia coli infections
0.644 0.356 0.000
A04.3 Enterohaemorrhagic Escherichia coli infection
0.644 0.356 0.000
A04.2 Enteroinvasive Escherichia coli infection
0.644 0.356 0.000
A04.1 Enterotoxigenic Escherichia coli infection
0.644 0.356 0.000
A04.0 Enteropathogenic Escherichia coli infection
0.644 0.356 0.000
M35.1 Other overlap syndromes
0.644 0.356 0.000
R40 Somnolence, stupor and coma
0.644 0.356 0.000
E04 Other non-toxic goitre
0.643 0.357 0.000
B00 Herpesviral [herpes simplex] infections
0.643 0.357 0.000
Y35-Y36 Legal intervention and operations of war
0.643 0.357 0.000
Y10-Y34 Event of undetermined intent
0.643 0.357 0.000
Y00-Y09 Assault
0.643 0.357 0.000
X85-X99 Assault
0.643 0.357 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.643 0.357 0.000
X50-X57 Overexertion, travel and privation
0.643 0.357 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.643 0.357 0.000
X30-X39 Exposure to forces of nature
0.643 0.357 0.000
X20-X29 Contact with venomous animals and plants
0.643 0.357 0.000
X10-X19 Contact with heat and hot substances
0.643 0.357 0.000
X00-X09 Exposure to smoke, fire and flames
0.643 0.357 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.643 0.357 0.000
W75-W84 Other accidental threats to breathing
0.643 0.357 0.000
W65-W74 Accidental drowning and submersion
0.643 0.357 0.000
W50-W64 Exposure to animate mechanical forces
0.643 0.357 0.000
V98-V99 Other and unspecified transport accidents
0.643 0.357 0.000
V95-V97 Air and space transport accidents
0.643 0.357 0.000
V90-V94 Water transport accidents
0.643 0.357 0.000
V80-V89 Other land transport accidents
0.643 0.357 0.000
V70-V79 Bus occupant injured in transport accident
0.643 0.357 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.643 0.357 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.643 0.357 0.000
V40-V49 Car occupant injured in transport accident
0.643 0.357 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.643 0.357 0.000
V01-V09 Pedestrian injured in transport accident
0.643 0.357 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.642 0.358 0.000
R07.0 Pain in throat
0.642 0.358 0.000
H50.9 Strabismus, unspecified
0.642 0.358 0.000
M65.34 Trigger finger-Hand
0.642 0.358 0.000
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)
0.641 0.359 0.000
G82.2 Paraplegia, unspecified
0.641 0.359 0.000
G83 Other paralytic syndromes
0.641 0.359 0.000
G80 Infantile cerebral palsy
0.641 0.359 0.000
G90-G99 Other disorders of the nervous system
0.640 0.360 0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts
0.640 0.360 0.000
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction
0.639 0.361 0.000
F02 Dementia in other diseases classified elsewhere
0.639 0.361 0.000
F09 Unspecified organic or symptomatic mental disorder
0.639 0.361 0.000
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances
0.639 0.361 0.000
T79.3 Post-traumatic wound infection, not elsewhere classified
0.638 0.362 0.000
A49.3 Mycoplasma infection, unspecified
0.636 0.363 0.000
A49.2 Haemophilus influenzae infection, unspecified
0.636 0.363 0.000
A49.1 Streptococcal infection, unspecified
0.636 0.363 0.000
R00 Abnormalities of heart beat
0.637 0.363 0.000
M25.47 Effusion of joint (Ankle and foot)
0.636 0.363 0.000
T78.2 Anaphylactic shock, unspecified
0.635 0.365 0.000
S50-S59 Injuries to the elbow and forearm
0.635 0.365 0.000
T31 Burns classified according to extent of body surface involved
0.635 0.365 0.000
A49.8 Other bacterial infections of unspecified site
0.634 0.365 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.634 0.366 0.000
F00 Dementia in Alzheimer's disease
0.634 0.366 0.000
H02.6 Xanthelasma of eyelid
0.634 0.366 0.000
R06.7 Sneezing
0.633 0.367 0.000
R06.6 Hiccough
0.633 0.367 0.000
R06.3 Periodic breathing
0.633 0.367 0.000
L82 Seborrhoeic keratosis
0.633 0.367 0.000
F01.9 Vascular dementia, unspecified
0.633 0.367 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.633 0.367 0.000
S64 Injury of nerves at wrist and hand level
0.632 0.368 0.000
R54 Senility
0.631 0.368 0.000
S27 Injury of other and unspecified intrathoracic organs
0.631 0.369 0.000
H61 Other disorders of external ear
0.631 0.369 0.000
T85.4 Mechanical complication of breast prosthesis and implant
0.630 0.369 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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