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Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs115380428
log Bayes Factor = 16.4549
Chromosome 5   position 18,099,592  (GRCh37) Explore rs115380428 on Ensembl!
Variant rs115380428 is part of Cluster X0232

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter XI Diseases of the digestive system
1.000 0.000 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.999 0.001 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.999 0.001 0.000
Chapter X Diseases of the respiratory system
0.998 0.002 0.000
T81 Complications of procedures, not elsewhere classified
0.997 0.003 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.995 0.005 0.000
K70-K77 Diseases of liver
0.995 0.005 0.000
R50-R69 General symptoms and signs
0.995 0.005 0.000
Chapter XIV Diseases of the genitourinary system
0.994 0.006 0.000
R69 Unknown and unspecified causes of morbidity
0.993 0.007 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.992 0.008 0.000
J30-J39 Other diseases of upper respiratory tract
0.989 0.011 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.987 0.013 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.976 0.024 0.000
Chapter I Certain infectious and parasitic diseases
0.969 0.031 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.966 0.034 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.964 0.036 0.000
Chapter V Mental and behavioural disorders
0.958 0.042 0.000
T81.8 Other complications of procedures, not elsewhere classified
0.957 0.043 0.000
N20-N23 Urolithiasis
0.957 0.043 0.000
Chapter VIII Diseases of the ear and mastoid process
0.953 0.047 0.000
K40-K46 Hernia
0.952 0.048 0.000
K90-K93 Other diseases of the digestive system
0.951 0.049 0.000
T81.4 Infection following a procedure, not elsewhere classified
0.950 0.050 0.000
J95-J99 Other diseases of the respiratory system
0.950 0.050 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.940 0.060 0.000
J32 Chronic sinusitis
0.939 0.061 0.000
T81.3 Disruption of operation wound, not elsewhere classified
0.938 0.062 0.000
E70-E90 Metabolic disorders
0.932 0.068 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.931 0.069 0.000
K43 Ventral hernia
0.930 0.070 0.000
N20 Calculus of kidney and ureter
0.925 0.075 0.000
K75 Other inflammatory liver diseases
0.920 0.080 0.000
Chapter XXII Codes for special purposes
0.916 0.084 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.915 0.085 0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.913 0.087 0.000
N10-N16 Renal tubulo-interstitial diseases
0.912 0.088 0.000
K43.9 Ventral hernia without obstruction or gangrene
0.910 0.090 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.909 0.091 0.000
L20-L30 Dermatitis and eczema
0.906 0.094 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.903 0.097 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.901 0.098 0.000
N60-N64 Disorders of breast
0.901 0.099 0.000
H65-H75 Diseases of middle ear and mastoid
0.900 0.100 0.000
K70 Alcoholic liver disease
0.899 0.101 0.000
Chapter VI Diseases of the nervous system
0.899 0.101 0.000
N20.0 Calculus of kidney
0.899 0.101 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.897 0.103 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.896 0.104 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.895 0.105 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.893 0.107 0.000
N30-N39 Other diseases of urinary system
0.892 0.108 0.000
O60-O75 Complications of labour and delivery
0.888 0.112 0.000
B95-B98 Bacterial, viral and other infectious agents
0.886 0.114 0.000
O36 Maternal care for other known or suspected foetal problems
0.885 0.115 0.000
F30-F39 Mood [affective] disorders
0.883 0.117 0.000
K35-K38 Diseases of appendix
0.879 0.121 0.000
N39 Other disorders of urinary system
0.877 0.123 0.000
N63 Unspecified lump in breast
0.876 0.124 0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.876 0.124 0.000
J98 Other respiratory disorders
0.876 0.124 0.000
N39.0 Urinary tract infection, site not specified
0.875 0.125 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.874 0.126 0.000
K91.4 Colostomy and enterostomy malfunction
0.871 0.129 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.867 0.133 0.000
K74 Fibrosis and cirrhosis of liver
0.866 0.134 0.000
O42 Premature rupture of membranes
0.866 0.134 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.865 0.135 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.862 0.138 0.000
J30 Vasomotor and allergic rhinitis
0.855 0.145 0.000
K72 Hepatic failure, not elsewhere classified
0.855 0.145 0.000
R55 Syncope and collapse
0.853 0.147 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.853 0.147 0.000
E87.5 Hyperkalaemia
0.853 0.147 0.000
O40 Polyhydramnios
0.853 0.147 0.000
R93.3 Abnormal findings on diagnostic imaging of other parts of digestive tract
0.851 0.149 0.000
A30-A49 Other bacterial diseases
0.851 0.149 0.000
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified
0.850 0.150 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.849 0.151 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.848 0.152 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.848 0.152 0.000
N40-N51 Diseases of male genital organs
0.848 0.152 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.846 0.154 0.000
J32.9 Chronic sinusitis, unspecified
0.844 0.156 0.000
J36 Peritonsillar abscess
0.842 0.158 0.000
L50-L54 Urticaria and erythema
0.839 0.161 0.000
F32 Depressive episode
0.836 0.164 0.000
K50-K52 Noninfective enteritis and colitis
0.835 0.165 0.000
L30 Other dermatitis
0.833 0.167 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.831 0.169 0.000
R47-R49 Symptoms and signs involving speech and voice
0.830 0.170 0.000
G30-G32 Other degenerative diseases of the nervous system
0.829 0.171 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.829 0.171 0.000
K76 Other diseases of liver
0.826 0.174 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.825 0.175 0.000
E87.6 Hypokalaemia
0.823 0.177 0.000
J90-J94 Other diseases of pleura
0.821 0.179 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.819 0.181 0.000
R41.0 Disorientation, unspecified
0.819 0.181 0.000
R68 Other general symptoms and signs
0.817 0.183 0.000
B35-B49 Mycoses
0.816 0.183 0.000
T66-T78 Other and unspecified effects of external causes
0.815 0.185 0.000
R93.2 Abnormal findings on diagnostic imaging of liver and biliary tract
0.813 0.187 0.000
U80 Agent resistant to penicillin and related antibiotics
0.809 0.191 0.000
R53 Malaise and fatigue
0.808 0.192 0.000
L92 Granulomatous disorders of skin and subcutaneous tissue
0.806 0.194 0.000
T40.2 Other opioids
0.804 0.196 0.000
F32.9 Depressive episode, unspecified
0.801 0.199 0.000
R93.8 Abnormal findings on diagnostic imaging of other specified body structures
0.801 0.199 0.000
O80-O84 Delivery
0.797 0.203 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.797 0.203 0.000
S20-S29 Injuries to the thorax
0.796 0.203 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.796 0.203 0.000
J32.8 Other chronic sinusitis
0.795 0.204 0.000
J38.3 Other diseases of vocal cords
0.795 0.205 0.000
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified
0.795 0.205 0.000
H65 Nonsuppurative otitis media
0.794 0.206 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.793 0.207 0.000
K75.9 Inflammatory liver disease, unspecified
0.792 0.208 0.000
E20-E35 Disorders of other endocrine glands
0.790 0.210 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.788 0.212 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.788 0.212 0.000
E65-E68 Obesity and other hyperalimentation
0.787 0.213 0.000
R60 Oedema, not elsewhere classified
0.787 0.213 0.000
H90-H95 Other disorders of ear
0.787 0.213 0.000
N99-N99 Other disorders of the genitourinary system
0.785 0.214 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.785 0.215 0.000
L30.9 Dermatitis, unspecified
0.782 0.218 0.000
R91 Abnormal findings on diagnostic imaging of lung
0.779 0.221 0.000
K74.6 Other and unspecified cirrhosis of liver
0.779 0.221 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.778 0.222 0.000
J38.1 Polyp of vocal cord and larynx
0.776 0.224 0.000
K91.3 Postoperative intestinal obstruction
0.775 0.225 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.774 0.226 0.000
K70.3 Alcoholic cirrhosis of liver
0.772 0.228 0.000
J81 Pulmonary oedema
0.771 0.229 0.000
J98.4 Other disorders of lung
0.771 0.229 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.770 0.230 0.000
K90 Intestinal malabsorption
0.769 0.231 0.000
R93.4 Abnormal findings on diagnostic imaging of urinary organs
0.768 0.232 0.000
N39.4 Other specified urinary incontinence
0.767 0.233 0.000
F10.1 Harmful use
0.767 0.233 0.000
K07 Dentofacial anomalies [including malocclusion]
0.765 0.235 0.000
T39.1 4-Aminophenol derivatives
0.764 0.236 0.000
E83 Disorders of mineral metabolism
0.764 0.236 0.000
S60-S69 Injuries to the wrist and hand
0.764 0.236 0.000
N10 Acute tubulo-interstitial nephritis
0.764 0.236 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.764 0.236 0.000
J98.1 Pulmonary collapse
0.763 0.237 0.000
K35 Acute appendicitis
0.763 0.237 0.000
A41 Other septicaemia
0.762 0.238 0.000
K70.9 Alcoholic liver disease, unspecified
0.762 0.238 0.000
O26 Maternal care for other conditions predominantly related to pregnancy
0.760 0.240 0.000
J32.2 Chronic ethmoidal sinusitis
0.760 0.240 0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.759 0.241 0.000
K12 Stomatitis and related lesions
0.757 0.242 0.000
J31.0 Chronic rhinitis
0.757 0.243 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.757 0.243 0.000
J80 Adult respiratory distress syndrome
0.757 0.243 0.000
J30.1 Allergic rhinitis due to pollen
0.756 0.244 0.000
R57 Shock, not elsewhere classified
0.755 0.244 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.755 0.244 0.000
S70-S79 Injuries to the hip and thigh
0.755 0.245 0.000
O70 Perineal laceration during delivery
0.752 0.248 0.000
K40 Inguinal hernia
0.752 0.248 0.000
K14 Diseases of tongue
0.752 0.248 0.000
R52 Pain, not elsewhere classified
0.751 0.249 0.000
T42.4 Benzodiazepines
0.751 0.249 0.000
S90-S99 Injuries to the ankle and foot
0.750 0.250 0.000
J39 Other diseases of upper respiratory tract
0.749 0.251 0.000
L82 Seborrhoeic keratosis
0.748 0.252 0.000
E50-E64 Other nutritional deficiencies
0.748 0.252 0.000
L90 Atrophic disorders of skin
0.747 0.252 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.745 0.255 0.000
R40 Somnolence, stupor and coma
0.744 0.256 0.000
K75.4 Autoimmune hepatitis
0.743 0.257 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.743 0.257 0.000
H60-H62 Diseases of external ear
0.741 0.258 0.000
J60-J70 Lung diseases due to external agents
0.741 0.259 0.000
O20 Haemorrhage in early pregnancy
0.741 0.259 0.000
L05 Pilonidal cyst
0.740 0.259 0.000
G20-G26 Extrapyramidal and movement disorders
0.738 0.262 0.000
N21 Calculus of lower urinary tract
0.737 0.263 0.000
O36.6 Maternal care for excessive foetal growth
0.736 0.264 0.000
H71 Cholesteatoma of middle ear
0.735 0.265 0.000
J95.8 Other postprocedural respiratory disorders
0.735 0.265 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.734 0.266 0.000
L93 Lupus erythematosus
0.734 0.266 0.000
S00-S09 Injuries to the head
0.733 0.266 0.000
L28 Lichen simplex chronicus and prurigo
0.733 0.266 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.732 0.268 0.000
K50 Crohn's disease [regional enteritis]
0.732 0.268 0.000
K76.6 Portal hypertension
0.732 0.268 0.000
E40-E46 Malnutrition
0.732 0.268 0.000
D75 Other diseases of blood and blood-forming organs
0.731 0.269 0.000
R50 Fever of unknown origin
0.731 0.269 0.000
Chapter XX External causes of morbidity and mortality
0.731 0.269 0.000
H66 Suppurative and unspecified otitis media
0.730 0.269 0.000
N47 Redundant prepuce, phimosis and paraphimosis
0.730 0.270 0.000
F80-F89 Disorders of psychological development
0.730 0.270 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.729 0.271 0.000
L50 Urticaria
0.729 0.271 0.000
E86 Volume depletion
0.727 0.273 0.000
U80.1 Methicillin resistant agent
0.726 0.274 0.000
K75.0 Abscess of liver
0.726 0.274 0.000
E87.0 Hyperosmolality and hypernatraemia
0.726 0.274 0.000
K43.0 Ventral hernia with obstruction, without gangrene
0.725 0.275 0.000
K72.9 Hepatic failure, unspecified
0.724 0.276 0.000
O71 Other obstetric trauma
0.723 0.277 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.722 0.277 0.000
E87.7 Fluid overload
0.722 0.277 0.000
N36 Other disorders of urethra
0.722 0.278 0.000
S40-S49 Injuries to the shoulder and upper arm
0.720 0.280 0.000
G30 Alzheimer's disease
0.719 0.281 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.718 0.281 0.000
O36.8 Maternal care for other specified foetal problems
0.717 0.283 0.000
T79-T79 Certain early complications of trauma
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
S10-S19 Injuries to the neck
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T87 Complications peculiar to reattachment and amputation
0.716 0.283 0.000
T86 Failure and rejection of transplanted organs and tissues
0.716 0.283 0.000
O24 Diabetes mellitus in pregnancy
0.716 0.284 0.000
F99-F99 Unspecified mental disorder
0.716 0.284 0.000
O72 Postpartum haemorrhage
0.716 0.284 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.716 0.284 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.715 0.285 0.000
G90-G99 Other disorders of the nervous system
0.715 0.285 0.000
T81.9 Unspecified complication of procedure
0.715 0.285 0.000
T81.7 Vascular complications following a procedure, not elsewhere classified
0.715 0.285 0.000
T81.6 Acute reaction to foreign substance accidentally left during a procedure
0.715 0.285 0.000
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure
0.715 0.285 0.000
T81.1 Shock during or resulting from a procedure, not elsewhere classified
0.715 0.285 0.000
O47 False labour
0.715 0.285 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.715 0.285 0.000
B25-B34 Other viral diseases
0.713 0.286 0.000
O85-O92 Complications predominantly related to the puerperium
0.713 0.286 0.000
K77 Liver disorders in diseases classified elsewhere
0.713 0.287 0.000
K73 Chronic hepatitis, not elsewhere classified
0.713 0.287 0.000
K71 Toxic liver disease
0.713 0.287 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.713 0.287 0.000
R62 Lack of expected normal physiological development
0.713 0.287 0.000
R64 Cachexia
0.713 0.287 0.000
R58 Haemorrhage, not elsewhere classified
0.713 0.287 0.000
J00-J06 Acute upper respiratory infections
0.713 0.287 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.711 0.289 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.711 0.289 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.711 0.289 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.711 0.289 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.711 0.289 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.711 0.289 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.711 0.289 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.711 0.289 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.711 0.289 0.000
T36 Poisoning by systemic antibiotics
0.711 0.289 0.000
L98.8 Other specified disorders of skin and subcutaneous tissue
0.711 0.289 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.711 0.289 0.000
L98.9 Disorder of skin and subcutaneous tissue, unspecified
0.710 0.290 0.000
K07.6 Temporomandibular joint disorders
0.710 0.290 0.000
H65.3 Chronic mucoid otitis media
0.710 0.290 0.000
J37 Chronic laryngitis and laryngotracheitis
0.709 0.291 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.709 0.291 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.708 0.292 0.000
L10-L14 Bullous disorders
0.708 0.292 0.000
O42.1 Premature rupture of membranes, onset of labour after 24 hours
0.708 0.292 0.000
T40.4 Other synthetic narcotics
0.707 0.293 0.000
J31.2 Chronic pharyngitis
0.707 0.293 0.000
K75.8 Other specified inflammatory liver diseases
0.706 0.294 0.000
J93 Pneumothorax
0.706 0.294 0.000
N48 Other disorders of penis
0.706 0.294 0.000
L85 Other epidermal thickening
0.705 0.295 0.000
K35.9 Acute appendicitis, unspecified
0.705 0.295 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.705 0.295 0.000
R93.0 Abnormal findings on diagnostic imaging of skull and head, not elsewhere classified
0.704 0.296 0.000
L60-L75 Disorders of skin appendages
0.701 0.299 0.000
O45 Premature separation of placenta [abruptio placentae]
0.700 0.300 0.000
O44 Placenta praevia
0.700 0.300 0.000
O43 Placental disorders
0.700 0.300 0.000
O41 Other disorders of amniotic fluid and membranes
0.700 0.300 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.700 0.300 0.000
O33 Maternal care for known or suspected disproportion
0.700 0.300 0.000
O31 Complications specific to multiple gestation
0.700 0.300 0.000
O30 Multiple gestation
0.700 0.300 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.700 0.300 0.000
H73 Other disorders of tympanic membrane
0.699 0.301 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.699 0.301 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.699 0.301 0.000
R49 Voice disturbances
0.698 0.302 0.000
K46 Unspecified abdominal hernia
0.697 0.303 0.000
G70-G73 Diseases of myoneural junction and muscle
0.697 0.303 0.000
B99-B99 Other infectious diseases
0.695 0.305 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.695 0.305 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.695 0.305 0.000
B65-B83 Helminthiases
0.695 0.305 0.000
B50-B64 Protozoal diseases
0.695 0.305 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.695 0.305 0.000
B15-B19 Viral hepatitis
0.695 0.305 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.695 0.305 0.000
A80-A89 Viral infections of the central nervous system
0.695 0.305 0.000
A75-A79 Rickettsioses
0.695 0.305 0.000
A70-A74 Other diseases caused by chlamydiae
0.695 0.305 0.000
A65-A69 Other spirochaetal diseases
0.695 0.305 0.000
A20-A28 Certain zoonotic bacterial diseases
0.695 0.305 0.000
A15-A19 Tuberculosis
0.695 0.305 0.000
O42.0 Premature rupture of membranes, onset of labour within 24 hours
0.694 0.306 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.694 0.306 0.000
N13 Obstructive and reflux uropathy
0.693 0.307 0.000
L90.0 Lichen sclerosus et atrophicus
0.693 0.307 0.000
T43.2 Other and unspecified antidepressants
0.693 0.307 0.000
L03 Cellulitis
0.692 0.308 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.692 0.308 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.692 0.308 0.000
K40.2 Bilateral inguinal hernia, without obstruction or gangrene
0.692 0.308 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.692 0.308 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.691 0.309 0.000
R92 Abnormal findings on diagnostic imaging of breast
0.691 0.309 0.000
D70 Agranulocytosis
0.691 0.309 0.000
K38 Other diseases of appendix
0.690 0.310 0.000
R68.8 Other specified general symptoms and signs
0.690 0.310 0.000
O42.9 Premature rupture of membranes, unspecified
0.689 0.310 0.000
U80.8 Agent resistant to other penicillin-related antibiotic
0.689 0.311 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.688 0.312 0.000
N20.1 Calculus of ureter
0.688 0.312 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.687 0.313 0.000
F70-F79 Mental retardation
0.687 0.313 0.000
F60-F69 Disorders of adult personality and behaviour
0.687 0.313 0.000
H92 Otalgia and effusion of ear
0.686 0.314 0.000
N22 Calculus of urinary tract in diseases classified elsewhere
0.686 0.314 0.000
F10.2 Dependence syndrome
0.686 0.314 0.000
T68 Hypothermia
0.685 0.315 0.000
J38.2 Nodules of vocal cords
0.684 0.315 0.000
N20.2 Calculus of kidney with calculus of ureter
0.684 0.316 0.000
K45 Other abdominal hernia
0.682 0.318 0.000
O36.5 Maternal care for poor foetal growth
0.682 0.318 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.682 0.318 0.000
O36.0 Maternal care for rhesus isoimmunisation
0.682 0.318 0.000
J99 Respiratory disorders in diseases classified elsewhere
0.681 0.319 0.000
J96 Respiratory failure, not elsewhere classified
0.681 0.319 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.678 0.322 0.000
O63 Long labour
0.678 0.322 0.000
L92.9 Granulomatous disorder of skin and subcutaneous tissue, unspecified
0.678 0.322 0.000
B49 Unspecified mycosis
0.677 0.323 0.000
K12.1 Other forms of stomatitis
0.677 0.323 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.675 0.325 0.000
B02 Zoster [herpes zoster]
0.675 0.325 0.000
Q80-Q89 Other congenital malformations
0.674 0.326 0.000
R93.7 Abnormal findings on diagnostic imaging of other parts of musculoskeletal system
0.674 0.326 0.000
R93.6 Abnormal findings on diagnostic imaging of limbs
0.674 0.326 0.000
K41 Femoral hernia
0.674 0.326 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.674 0.326 0.000
J32.4 Chronic pansinusitis
0.673 0.327 0.000
J32.3 Chronic sphenoidal sinusitis
0.673 0.327 0.000
J32.1 Chronic frontal sinusitis
0.673 0.327 0.000
N40 Hyperplasia of prostate
0.673 0.327 0.000
N23 Unspecified renal colic
0.672 0.328 0.000
K72.0 Acute and subacute hepatic failure
0.670 0.330 0.000
E85 Amyloidosis
0.668 0.332 0.000
E84 Cystic fibrosis
0.668 0.332 0.000
E79 Disorders of purine and pyrimidine metabolism
0.668 0.332 0.000
E77 Disorders of glycoprotein metabolism
0.668 0.332 0.000
E76 Disorders of glycosaminoglycan metabolism
0.668 0.332 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.668 0.332 0.000
E74 Other disorders of carbohydrate metabolism
0.668 0.332 0.000
E73 Lactose intolerance
0.668 0.332 0.000
E72 Other disorders of amino-acid metabolism
0.668 0.332 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.668 0.332 0.000
E70 Disorders of aromatic amino-acid metabolism
0.668 0.332 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.668 0.332 0.000
E88 Other metabolic disorders
0.668 0.332 0.000
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.668 0.332 0.000
L95 Vasculitis limited to skin, not elsewhere classified
0.668 0.332 0.000
L94 Other localised connective tissue disorders
0.668 0.332 0.000
L87 Transepidermal elimination disorders
0.668 0.332 0.000
L88 Pyoderma gangrenosum
0.668 0.332 0.000
L86 Keratoderma in diseases classified elsewhere
0.668 0.332 0.000
L83 Acanthosis nigricans
0.668 0.332 0.000
L80 Vitiligo
0.668 0.332 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.667 0.333 0.000
K43.7 Other and unspecified ventral hernia with gangrene
0.667 0.333 0.000
K43.6 Other and unspecified ventral hernia with obstruction, without gangrene
0.667 0.333 0.000
K43.5 Parastomal hernia without obstruction or gangrene
0.667 0.333 0.000
K43.4 Parastomal hernia with gangrene
0.667 0.333 0.000
K43.3 Parastomal hernia with obstruction, without gangrene
0.667 0.333 0.000
K43.2 Incisional hernia without obstruction or gangrene
0.667 0.333 0.000
K43.1 Ventral hernia with gangrene
0.667 0.333 0.000
K00 Disorders of tooth development and eruption
0.665 0.335 0.000
K51 Ulcerative colitis
0.665 0.335 0.000
J32.0 Chronic maxillary sinusitis
0.664 0.336 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.664 0.336 0.000
N20.9 Urinary calculus, unspecified
0.663 0.336 0.000
L05.9 Pilonidal cyst without abscess
0.663 0.337 0.000
K65-K67 Diseases of peritoneum
0.662 0.337 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.662 0.338 0.000
J84 Other interstitial pulmonary diseases
0.662 0.338 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.661 0.339 0.000
E87.2 Acidosis
0.660 0.340 0.000
D73 Diseases of spleen
0.660 0.340 0.000
K75.3 Granulomatous hepatitis, not elsewhere classified
0.660 0.340 0.000
K75.2 Nonspecific reactive hepatitis
0.660 0.340 0.000
K75.1 Phlebitis of portal vein
0.660 0.340 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.660 0.340 0.000
E66 Obesity
0.660 0.340 0.000
L98.4 Chronic ulcer of skin, not elsewhere classified
0.659 0.341 0.000
S50-S59 Injuries to the elbow and forearm
0.659 0.341 0.000
D55-D59 Haemolytic anaemias
0.659 0.341 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.658 0.342 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.658 0.342 0.000
R93.1 Abnormal findings on diagnostic imaging of heart and coronary circulation
0.657 0.343 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.656 0.343 0.000
F31 Bipolar affective disorder
0.656 0.344 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.656 0.344 0.000
E87.4 Mixed disorder of acid-base balance
0.656 0.344 0.000
E87.3 Alkalosis
0.656 0.344 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.655 0.345 0.000
K91.9 Postprocedural disorder of digestive system, unspecified
0.654 0.345 0.000
K91.5 Postcholecystectomy syndrome
0.654 0.345 0.000
K91.2 Postsurgical malabsorption, not elsewhere classified
0.654 0.345 0.000
K91.1 Postgastric surgery syndromes
0.654 0.345 0.000
K91.0 Vomiting following gastro-intestinal surgery
0.654 0.345 0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere
0.654 0.346 0.000
N15 Other renal tubulo-interstitial diseases
0.654 0.346 0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
0.654 0.346 0.000
N11 Chronic tubulo-interstitial nephritis
0.654 0.346 0.000
A41.1 Septicaemia due to other specified staphylococcus
0.654 0.346 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.653 0.347 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.652 0.348 0.000
R46 Symptoms and signs involving appearance and behaviour
0.652 0.348 0.000
R43 Disturbances of smell and taste
0.652 0.348 0.000
J09-J18 Influenza and pneumonia
0.650 0.350 0.000
L25 Unspecified contact dermatitis
0.649 0.351 0.000
L24 Irritant contact dermatitis
0.649 0.351 0.000
L23 Allergic contact dermatitis
0.649 0.351 0.000
L21 Seborrhoeic dermatitis
0.649 0.351 0.000
L20 Atopic dermatitis
0.649 0.351 0.000
L26 Exfoliative dermatitis
0.649 0.351 0.000
L22 Diaper [napkin] dermatitis
0.649 0.351 0.000
O34.7 Maternal care for abnormality of vulva and perineum
0.649 0.351 0.000
R21 Rash and other nonspecific skin eruption
0.648 0.352 0.000
R45 Symptoms and signs involving emotional state
0.647 0.353 0.000
O29 Complications of anaesthesia during pregnancy
0.647 0.353 0.000
O28 Abnormal findings on antenatal screening of mother
0.647 0.353 0.000
O23 Infections of genito-urinary tract in pregnancy
0.647 0.353 0.000
O22 Venous complications in pregnancy
0.647 0.353 0.000
O21 Excessive vomiting in pregnancy
0.647 0.353 0.000
O25 Malnutrition in pregnancy
0.647 0.353 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.647 0.353 0.000
J38.0 Paralysis of vocal cords and larynx
0.646 0.353 0.000
J82 Pulmonary eosinophilia, not elsewhere classified
0.646 0.354 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.646 0.354 0.000
H74 Other disorders of middle ear and mastoid
0.646 0.354 0.000
H70 Mastoiditis and related conditions
0.646 0.354 0.000
H69 Other disorders of Eustachian tube
0.646 0.354 0.000
H68 Eustachian salpingitis and obstruction
0.646 0.354 0.000
H67 Otitis media in diseases classified elsewhere
0.646 0.354 0.000
L92.3 Foreign body granuloma of skin and subcutaneous tissue
0.645 0.355 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.645 0.355 0.000
O26.9 Pregnancy-related condition, unspecified
0.645 0.355 0.000
K70.4 Alcoholic hepatic failure
0.645 0.355 0.000
K70.2 Alcoholic fibrosis and sclerosis of liver
0.645 0.355 0.000
K70.1 Alcoholic hepatitis
0.645 0.355 0.000
K70.0 Alcoholic fatty liver
0.645 0.355 0.000
N71 Inflammatory disease of uterus, except cervix
0.643 0.357 0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft
0.643 0.357 0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis
0.643 0.357 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.643 0.357 0.000
T82.4 Mechanical complication of vascular dialysis catheter
0.643 0.357 0.000
T82.3 Mechanical complication of other vascular grafts
0.643 0.357 0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts
0.643 0.357 0.000
T82.0 Mechanical complication of heart valve prosthesis
0.643 0.357 0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]
0.642 0.358 0.000
T40.8 Lysergide [LSD]
0.642 0.358 0.000
T40.7 Cannabis (derivatives)
0.642 0.358 0.000
T40.6 Other and unspecified narcotics
0.642 0.358 0.000
T40.5 Cocaine
0.642 0.358 0.000
T40.3 Methadone
0.642 0.358 0.000
T40.1 Heroin
0.642 0.358 0.000
T40.0 Opium
0.642 0.358 0.000
J35 Chronic diseases of tonsils and adenoids
0.642 0.358 0.000
R23 Other skin changes
0.642 0.358 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.642 0.358 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.641 0.358 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.641 0.358 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.641 0.358 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.641 0.358 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.641 0.358 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.641 0.358 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.641 0.358 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.641 0.358 0.000
F11 Mental and behavioural disorders due to use of opioids
0.641 0.358 0.000
K14.0 Glossitis
0.641 0.359 0.000
J94 Other pleural conditions
0.640 0.360 0.000
J38.6 Stenosis of larynx
0.640 0.360 0.000
J38.5 Laryngeal spasm
0.640 0.360 0.000
J38.4 Oedema of larynx
0.640 0.360 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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