TreeWAS – Variant ID: rs115400054

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I25.1 Atherosclerotic heart disease	1.000	0.000	0.000
I25 Chronic ischaemic heart disease	1.000	0.000	0.000
I21 Acute myocardial infarction	1.000	0.000	0.000
I20-I25 Ischaemic heart diseases	1.000	0.000	0.000
I21.9 Acute myocardial infarction, unspecified	1.000	0.000	0.000
I25.2 Old myocardial infarction	0.999	0.001	0.000
I20 Angina pectoris	0.998	0.002	0.000
Z95.5 Presence of coronary angioplasty implant and graft	0.996	0.004	0.000
I20.9 Angina pectoris, unspecified	0.993	0.007	0.000
I21.0 Acute transmural myocardial infarction of anterior wall	0.991	0.009	0.000
I25.8 Other forms of chronic ischaemic heart disease	0.990	0.010	0.000
I20.0 Unstable angina	0.980	0.020	0.000
I25.9 Chronic ischaemic heart disease, unspecified	0.923	0.077	0.000
I22 Subsequent myocardial infarction	0.922	0.078	0.000
I24 Other acute ischaemic heart diseases	0.878	0.122	0.000
I21.3 Acute transmural myocardial infarction of unspecified site	0.841	0.159	0.000
I24.9 Acute ischaemic heart disease, unspecified	0.826	0.174	0.000
I22.0 Subsequent myocardial infarction of anterior wall	0.811	0.189	0.000
I25.4 Coronary artery aneurysm	0.808	0.192	0.000
I22.1 Subsequent myocardial infarction of inferior wall	0.803	0.197	0.000
M19.9 Arthrosis, unspecified	0.000	0.244	0.756
M19 Other arthrosis	0.000	0.247	0.753
M19.94 Arthrosis, unspecified (Hand)	0.000	0.249	0.751
M15-M19 Arthrosis	0.000	0.262	0.738
I23 Certain current complications following acute myocardial infarction	0.737	0.263	0.000
M18 Arthrosis of first carpometacarpal joint	0.000	0.266	0.734
M19.0 Primary arthrosis of other joints	0.000	0.277	0.723
M18.9 Arthrosis of first carpometacarpal joint, unspecified	0.000	0.281	0.719
I21.X Presumed acute myicardial infaction (unconfirmed)	0.717	0.283	0.000
I25.6 Silent myocardial ischaemia	0.717	0.283	0.000
I22.8 Subsequent myocardial infarction of other sites	0.710	0.290	0.000
M17 Gonarthrosis [arthrosis of knee]	0.000	0.292	0.708
M17.9 Gonarthrosis, unspecified	0.000	0.295	0.705
M19.99 Arthrosis, unspecified (Site unspecified)	0.000	0.307	0.693
M19.01 Primary arthrosis of other joints (Shoulder region)	0.000	0.309	0.691
M18.1 Other primary arthrosis of first carpometacarpal joint	0.000	0.312	0.688
I25.3 Aneurysm of heart	0.672	0.328	0.000
I21.1 Acute transmural myocardial infarction of inferior wall	0.661	0.339	0.000
I21.4 Acute subendocardial myocardial infarction	0.656	0.344	0.000
I21.2 Acute transmural myocardial infarction of other sites	0.654	0.346	0.000
I25.5 Ischaemic cardiomyopathy	0.648	0.352	0.000
M19.07 Primary arthrosis of other joints (Ankle and foot)	0.000	0.376	0.624
M19.93 Arthrosis, unspecified (Forearm)	0.000	0.376	0.624
M19.91 Arthrosis, unspecified (Shoulder region)	0.000	0.383	0.617
I24.1 Dressler's syndrome	0.609	0.391	0.000
M19.92 Arthrosis, unspecified (Upper arm)	0.000	0.402	0.598
I25.0 Atherosclerotic cardiovascular disease, so described	0.596	0.403	0.000
I67 Other cerebrovascular diseases	0.000	0.408	0.592
I24.8 Other forms of acute ischaemic heart disease	0.581	0.419	0.000
I60-I69 Cerebrovascular diseases	0.000	0.422	0.578
M19.90 Arthrosis, unspecified (Multiple sites)	0.000	0.425	0.575
I22.9 Subsequent myocardial infarction of unspecified site	0.569	0.431	0.000
I67.8 Other specified cerebrovascular diseases	0.000	0.434	0.566
M19.02 Primary arthrosis of other joints (Upper arm)	0.000	0.440	0.560
M19.2 Other secondary arthrosis	0.000	0.443	0.557
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.555	0.445	0.000
I69 Sequelae of cerebrovascular disease	0.000	0.450	0.550
I67.1 Cerebral aneurysm, nonruptured	0.000	0.450	0.550
I23.8 Other current complications following acute myocardial infarction	0.549	0.451	0.000
I67.9 Cerebrovascular disease, unspecified	0.000	0.454	0.546
I20.1 Angina pectoris with documented spasm	0.543	0.457	0.000
M19.8 Other specified arthrosis	0.000	0.460	0.540
I61 Intracerebral haemorrhage	0.000	0.460	0.540
I67.2 Cerebral atherosclerosis	0.000	0.467	0.533
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction	0.529	0.471	0.000
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction	0.529	0.471	0.000
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction	0.529	0.471	0.000
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction	0.529	0.471	0.000
I23.2 Ventricular septal defect as current complication following acute myocardial infarction	0.529	0.471	0.000
I23.1 Atrial septal defect as current complication following acute myocardial infarction	0.529	0.471	0.000
I23.0 Haemopericardium as current complication following acute myocardial infarction	0.529	0.471	0.000
M18.5 Other secondary arthrosis of first carpometacarpal joint	0.000	0.474	0.526
M18.4 Other secondary arthrosis of first carpometacarpal joints, bilateral	0.000	0.474	0.526
M18.3 Other posttraumatic arthrosis of first carpometacarpal joint	0.000	0.474	0.526
M18.2 Posttraumatic arthrosis of first carpometacarpal joints, bilateral	0.000	0.474	0.526
M19.96 Arthrosis, unspecified-Lower leg	0.000	0.479	0.521
M15 Polyarthrosis	0.000	0.480	0.520
M19.08 Primary arthrosis of other joints (Other)	0.000	0.482	0.518
M19.05 Primary arthrosis of other joints (Pelvic region and thigh)	0.000	0.482	0.518
M19.00 Primary arthrosis of other joints (Multiple sites)	0.000	0.482	0.518
M19.04 Primary arthrosis of other joints (Hand)	0.000	0.489	0.511
I64 Stroke, not specified as haemorrhage or infarction	0.000	0.491	0.509
I61.9 Intracerebral haemorrhage, unspecified	0.000	0.492	0.508
M17.4 Other secondary gonarthrosis, bilateral	0.000	0.493	0.507
M17.2 Posttraumatic gonarthrosis, bilateral	0.000	0.493	0.507
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.000	0.493	0.507
M19.98 Arthrosis, unspecified (Other)	0.000	0.495	0.505
M19.95 Arthrosis, unspecified (Pelvic region and thigh)	0.000	0.496	0.504
I63 Cerebral infarction	0.000	0.502	0.498
M17.3 Other posttraumatic gonarthrosis	0.000	0.504	0.496
M19.06 Primary arthrosis of other joints-Lower leg	0.000	0.505	0.495
I61.5 Intracerebral haemorrhage, intraventricular	0.000	0.508	0.492
M19.09 Primary arthrosis of other joints (Site unspecified)	0.000	0.509	0.491
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.000	0.518	0.481
M17.1 Other primary gonarthrosis	0.000	0.524	0.476
M18.0 Primary arthrosis of first carpometacarpal joints, bilateral	0.000	0.527	0.473
M19.03 Primary arthrosis of other joints (Forearm)	0.000	0.558	0.442
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.000	0.562	0.438
M17.5 Other secondary gonarthrosis	0.000	0.574	0.425
I67.7 Cerebral arteritis, not elsewhere classified	0.000	0.576	0.424
I67.6 Nonpyogenic thrombosis of intracranial venous system	0.000	0.576	0.424
I67.5 Moyamoya disease	0.000	0.576	0.424
I67.4 Hypertensive encephalopathy	0.000	0.576	0.424
I67.3 Progressive vascular leukoencephalopathy	0.000	0.576	0.424
I67.0 Dissection of cerebral arteries, nonruptured	0.000	0.578	0.422
I63.4 Cerebral infarction due to embolism of cerebral arteries	0.000	0.579	0.421
I69.1 Sequelae of intracerebral haemorrhage	0.000	0.580	0.420
M19.27 Other secondary arthrosis (Ankle and foot)	0.000	0.584	0.416
I69.0 Sequelae of subarachnoid haemorrhage	0.000	0.585	0.415
I68 Cerebrovascular disorders in diseases classified elsewhere	0.000	0.586	0.414
M19.1 Posttraumatic arthrosis of other joints	0.000	0.590	0.410
I71 Aortic aneurysm and dissection	0.000	0.593	0.407
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.000	0.598	0.402
M19.29 Other secondary arthrosis (Site unspecified)	0.000	0.600	0.399
M19.28 Other secondary arthrosis (Other)	0.000	0.600	0.399
M19.26 Other secondary arthrosis of other joints-Lower leg	0.000	0.600	0.399
M19.25 Other secondary arthrosis (Pelvic region and thigh)	0.000	0.600	0.399
M19.24 Other secondary arthrosis (Hand)	0.000	0.600	0.399
M19.23 Other secondary arthrosis (Forearm)	0.000	0.600	0.399
M19.22 Other secondary arthrosis (Upper arm)	0.000	0.600	0.399
M19.21 Other secondary arthrosis (Shoulder region)	0.000	0.600	0.399
M19.20 Other secondary arthrosis (Multiple sites)	0.000	0.600	0.399
I63.9 Cerebral infarction, unspecified	0.000	0.606	0.394
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.000	0.607	0.393
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.000	0.608	0.392
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.000	0.609	0.391
M19.89 Other specified arthrosis (Site unspecified)	0.000	0.612	0.387
M19.88 Other specified arthrosis (Other)	0.000	0.612	0.387
M19.87 Other specified arthrosis (Ankle and foot)	0.000	0.612	0.387
M19.86 Other specified arthrosis (Lower leg)	0.000	0.612	0.387
M19.85 Other specified arthrosis (Pelvic region and thigh)	0.000	0.612	0.387
M19.84 Other specified arthrosis (Hand)	0.000	0.612	0.387
M19.83 Other specified arthrosis (Forearm)	0.000	0.612	0.387
M19.82 Other specified arthrosis (Upper arm)	0.000	0.612	0.387
M19.81 Other specified arthrosis (Shoulder region)	0.000	0.612	0.387
M19.80 Other specified arthrosis (Multiple sites)	0.000	0.612	0.387
I61.6 Intracerebral haemorrhage, multiple localised	0.000	0.613	0.387
I61.3 Intracerebral haemorrhage in brain stem	0.000	0.613	0.387
I61.2 Intracerebral haemorrhage in hemisphere, unspecified	0.000	0.613	0.387
I61.0 Intracerebral haemorrhage in hemisphere, subcortical	0.000	0.613	0.387
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.000	0.621	0.379
M15.9 Polyarthrosis, unspecified	0.000	0.627	0.373
M15.0 Primary generalised (osteo)arthrosis	0.000	0.627	0.373
M15.4 Erosive (osteo)arthrosis	0.000	0.627	0.373
M15.3 Secondary multiple arthrosis	0.000	0.627	0.373
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.000	0.628	0.372
M15.8 Other polyarthrosis	0.000	0.628	0.371
M15.1 Heberden's nodes (with arthropathy)	0.000	0.629	0.371
M15.2 Bouchard's nodes (with arthropathy)	0.000	0.632	0.368
I71.0 Dissection of aorta [any part]	0.000	0.635	0.365
I62 Other nontraumatic intracranial haemorrhage	0.000	0.636	0.364
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.000	0.638	0.362
I69.3 Sequelae of cerebral infarction	0.000	0.640	0.360
I61.8 Other intracerebral haemorrhage	0.000	0.642	0.358
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic	0.000	0.643	0.357
I63.1 Cerebral infarction due to embolism of precerebral arteries	0.000	0.643	0.357
I63.8 Other cerebral infarction	0.000	0.669	0.331
I20.8 Other forms of angina pectoris	0.330	0.670	0.000
I60 Subarachnoid haemorrhage	0.000	0.676	0.324
I61.4 Intracerebral haemorrhage in cerebellum	0.000	0.680	0.319
I71.3 Abdominal aortic aneurysm, ruptured	0.000	0.685	0.315
M19.97 Arthrosis, unspecified (Ankle and foot)	0.000	0.692	0.308
I61.1 Intracerebral haemorrhage in hemisphere, cortical	0.000	0.692	0.308
I63.0 Cerebral infarction due to thrombosis of precerebral arteries	0.000	0.693	0.307
M19.13 Post-traumatic arthrosis of other joints (Forearm)	0.000	0.694	0.306
Z95.1 Presence of aortocoronary bypass graft	0.304	0.696	0.000
Z95 Presence of cardiac and vascular implants and grafts	0.301	0.699	0.000
I68.8 Other cerebrovascular disorders in diseases classified elsewhere	0.000	0.703	0.297
I68.2 Cerebral arteritis in other diseases classified elsewhere	0.000	0.703	0.297
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere	0.000	0.703	0.297
I68.0 Cerebral amyloid angiopathy	0.000	0.703	0.297
I62.9 Intracranial haemorrhage (nontraumatic), unspecified	0.000	0.703	0.296
M19.19 Post-traumatic arthrosis of other joints (Site unspecified)	0.000	0.705	0.294
M19.18 Post-traumatic arthrosis of other joints (Other)	0.000	0.705	0.294
M19.16 Post-traumatic arthrosis of other joints-Lower leg	0.000	0.705	0.294
M19.15 Post-traumatic arthrosis of other joints (Pelvic region and thigh)	0.000	0.705	0.294
M19.14 Post-traumatic arthrosis of other joints (Hand)	0.000	0.705	0.294
M19.12 Post-traumatic arthrosis of other joints (Upper arm)	0.000	0.705	0.294
M19.10 Post-traumatic arthrosis of other joints (Multiple sites)	0.000	0.705	0.294
I71.8 Aortic aneurysm of unspecified site, ruptured	0.000	0.708	0.292
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.000	0.708	0.292
I71.1 Thoracic aortic aneurysm, ruptured	0.000	0.708	0.292
M19.11 Post-traumatic arthrosis of other joints (Shoulder region)	0.000	0.716	0.284
I66.8 Occlusion and stenosis of other cerebral artery	0.000	0.719	0.281
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries	0.000	0.719	0.281
I66.3 Occlusion and stenosis of cerebellar arteries	0.000	0.719	0.281
I66.2 Occlusion and stenosis of posterior cerebral artery	0.000	0.719	0.281
I66.1 Occlusion and stenosis of anterior cerebral artery	0.000	0.719	0.281
I66.0 Occlusion and stenosis of middle cerebral artery	0.000	0.719	0.281
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.000	0.730	0.270
M15.00 Primary generalized (osteo)arthrosis, Multiple sites	0.000	0.732	0.268
M15.99 Polyosteoarthritis, unspecified	0.000	0.732	0.268
I62.1 Nontraumatic extradural haemorrhage	0.000	0.739	0.261
I65.9 Occlusion and stenosis of unspecified precerebral artery	0.000	0.740	0.259
I65.8 Occlusion and stenosis of other precerebral artery	0.000	0.740	0.259
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries	0.000	0.740	0.259
I65.1 Occlusion and stenosis of basilar artery	0.000	0.740	0.259
I66.9 Occlusion and stenosis of unspecified cerebral artery	0.000	0.742	0.258
I65.2 Occlusion and stenosis of carotid artery	0.000	0.744	0.256
I63.3 Cerebral infarction due to thrombosis of cerebral arteries	0.000	0.750	0.250
I60.3 Subarachnoid haemorrhage from posterior communicating artery	0.000	0.751	0.248
I60.2 Subarachnoid haemorrhage from anterior communicating artery	0.000	0.756	0.244
I60.1 Subarachnoid haemorrhage from middle cerebral artery	0.000	0.760	0.240
I60.6 Subarachnoid haemorrhage from other intracranial arteries	0.000	0.768	0.232
I60.5 Subarachnoid haemorrhage from vertebral artery	0.000	0.768	0.232
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation	0.000	0.768	0.232
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified	0.000	0.768	0.232
I60.4 Subarachnoid haemorrhage from basilar artery	0.000	0.772	0.227
I60.8 Other subarachnoid haemorrhage	0.000	0.779	0.221
I65.0 Occlusion and stenosis of vertebral artery	0.000	0.788	0.212
M17.0 Primary gonarthrosis, bilateral	0.000	0.815	0.185
Z95.3 Presence of xenogenic heart valve	0.162	0.837	0.000
M19.17 Post-traumatic arthrosis of other joints (Ankle and foot)	0.001	0.840	0.159
Z95.9 Presence of cardiac and vascular implant and graft, unspecified	0.157	0.842	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.000	0.844	0.156
Z95.4 Presence of other heart-valve replacement	0.145	0.855	0.000
Chapter IX Diseases of the circulatory system	0.004	0.864	0.132
Z95.0 Presence of cardiac pacemaker	0.132	0.868	0.000
I62.0 Subdural haemorrhage (acute) (nontraumatic)	0.001	0.871	0.129
I77 Other disorders of arteries and arterioles	0.000	0.873	0.127
I78 Diseases of capillaries	0.000	0.886	0.114
I72 Other aneurysm	0.000	0.887	0.113
I77.9 Disorder of arteries and arterioles, unspecified	0.000	0.892	0.108
I77.8 Other specified disorders of arteries and arterioles	0.000	0.894	0.106
I77.0 Arteriovenous fistula, acquired	0.000	0.898	0.102
I78.1 Naevus, nonneoplastic	0.000	0.901	0.099
I70 Atherosclerosis	0.000	0.902	0.098
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.000	0.902	0.097
I00-I02 Acute rheumatic fever	0.003	0.908	0.089
I77.5 Necrosis of artery	0.000	0.909	0.091
I77.4 Coeliac artery compression syndrome	0.000	0.909	0.091
I77.3 Arterial fibromuscular dysplasia	0.000	0.909	0.091
I77.2 Rupture of artery	0.000	0.909	0.091
I72.4 Aneurysm of artery of lower extremity	0.000	0.909	0.091
I60.9 Subarachnoid haemorrhage, unspecified	0.000	0.910	0.090
Z95.8 Presence of other cardiac and vascular implants and grafts	0.086	0.914	0.000
I72.9 Aneurysm of unspecified site	0.000	0.915	0.085
I72.2 Aneurysm of renal artery	0.000	0.917	0.083
T39.1 4-Aminophenol derivatives	0.000	0.918	0.082
I78.9 Disease of capillaries, unspecified	0.000	0.918	0.082
I72.3 Aneurysm of iliac artery	0.000	0.918	0.082
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.000	0.918	0.082
I72.6 Aneurysm and dissection of vertebral artery	0.000	0.919	0.081
I72.5 Aneurysm and dissection of other precerebral arteries	0.000	0.919	0.081
I72.1 Aneurysm of artery of upper extremity	0.000	0.919	0.081
T36-T50 Poisoning by drugs, medicaments and biological substances	0.000	0.919	0.081
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.000	0.920	0.080
T42.4 Benzodiazepines	0.000	0.921	0.079
I77.1 Stricture of artery	0.000	0.923	0.077
I78.0 Hereditary haemorrhagic telangiectasia	0.000	0.924	0.076
I70.2 Atherosclerosis of arteries of the extremities	0.000	0.927	0.073
I72.8 Aneurysm of other specified arteries	0.000	0.927	0.073
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.000	0.928	0.072
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.000	0.929	0.071
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.000	0.929	0.071
I70.9 Generalised and unspecified atherosclerosis	0.000	0.929	0.070
I70.8 Atherosclerosis of other arteries	0.000	0.929	0.070
T43.2 Other and unspecified antidepressants	0.000	0.929	0.071
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.000	0.930	0.070
I79.1 Aortitis in diseases classified elsewhere	0.000	0.930	0.070
I79.0 Aneurysm of aorta in diseases classified elsewhere	0.000	0.930	0.070
I72.0 Aneurysm of carotid artery	0.000	0.932	0.068
K57.3 Diverticular disease of large intestine without perforation or abscess	0.000	0.932	0.068
I02 Rheumatic chorea	0.002	0.934	0.064
I01 Rheumatic fever with heart involvement	0.002	0.934	0.064
K57 Diverticular disease of intestine	0.000	0.934	0.066
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.000	0.934	0.066
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified	0.000	0.934	0.066
J44 Other chronic obstructive pulmonary disease	0.000	0.934	0.066
I05-I09 Chronic rheumatic heart diseases	0.003	0.934	0.062
Z95.2 Presence of prosthetic heart valve	0.064	0.935	0.000
I70.1 Atherosclerosis of renal artery	0.000	0.936	0.063
K57.2 Diverticular disease of large intestine with perforation and abscess	0.000	0.937	0.063
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection	0.000	0.937	0.063
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.000	0.937	0.063
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.000	0.937	0.063
I70.0 Atherosclerosis of aorta	0.000	0.938	0.062
I78.8 Other diseases of capillaries	0.000	0.938	0.062
T40.6 Other and unspecified narcotics	0.000	0.939	0.061
I00 Rheumatic fever without mention of heart involvement	0.003	0.939	0.058
K57.1 Diverticular disease of small intestine without perforation or abscess	0.000	0.940	0.060
T36 Poisoning by systemic antibiotics	0.000	0.940	0.060
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.000	0.940	0.060
T40.4 Other synthetic narcotics	0.000	0.941	0.059
I77.6 Arteritis, unspecified	0.000	0.941	0.059
K57.9 Diverticular disease of intestine, part unspecified, without perforation or abscess	0.000	0.941	0.059
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.000	0.941	0.059
T39.4 Antirheumatics, not elsewhere classified	0.000	0.941	0.059
T39.2 Pyrazolone derivatives	0.000	0.941	0.059
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.003	0.941	0.056
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.000	0.941	0.058
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.000	0.942	0.058
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.000	0.942	0.058
T41 Poisoning by anaesthetics and therapeutic gases	0.000	0.942	0.058
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.000	0.942	0.057
T42.5 Mixed antiepileptics, not elsewhere classified	0.000	0.942	0.057
T42.3 Barbiturates	0.000	0.942	0.057
T42.2 Succinimides and oxazolidinediones	0.000	0.942	0.057
T42.1 Iminostilbenes	0.000	0.942	0.057
T42.0 Hydantoin derivatives	0.000	0.942	0.057
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.000	0.943	0.057
J40-J47 Chronic lower respiratory diseases	0.000	0.943	0.057
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.000	0.943	0.057
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.000	0.944	0.056
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.000	0.944	0.056
T45.0 Antiallergic and antiemetic drugs	0.000	0.944	0.056
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.000	0.945	0.055
T46 Poisoning by agents primarily affecting the cardiovascular system	0.000	0.945	0.055
J44.8 Other specified chronic obstructive pulmonary disease	0.000	0.945	0.055
J45 Asthma	0.000	0.946	0.054
I74 Arterial embolism and thrombosis	0.000	0.948	0.052
T43.9 Psychotropic drug, unspecified	0.000	0.949	0.051
T43.8 Other psychotropic drugs, not elsewhere classified	0.000	0.949	0.051
T43.6 Psychostimulants with abuse potential	0.000	0.949	0.051
T43.4 Butyrophenone and thioxanthene neuroleptics	0.000	0.949	0.051
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.000	0.949	0.051
J40 Bronchitis, not specified as acute or chronic	0.000	0.949	0.051
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.000	0.949	0.051
T40.8 Lysergide [LSD]	0.000	0.949	0.051
T40.7 Cannabis (derivatives)	0.000	0.949	0.051
T40.5 Cocaine	0.000	0.949	0.051
T40.3 Methadone	0.000	0.949	0.051
T40.1 Heroin	0.000	0.949	0.051
T40.0 Opium	0.000	0.949	0.051
I70.81 Atherosclerosis of other arteries (with gangrene)	0.000	0.949	0.051
I70.80 Atherosclerosis of other arteries (without gangrene)	0.000	0.949	0.051
I70.91 Generalized and unspecified atherosclerosis (with gangrene)	0.000	0.949	0.051
I70.90 Generalized and unspecified atherosclerosis (without gangrene)	0.000	0.949	0.051
K57.0 Diverticular disease of small intestine with perforation and abscess	0.000	0.949	0.051
T45.1 Antineoplastic and immunosuppressive drugs	0.000	0.949	0.051
K57.5 Diverticular disease of both small and large intestine without perforation or abscess	0.000	0.950	0.050
J45.0 Predominantly allergic asthma	0.000	0.950	0.050
T47.1 Other antacids and anti-gastric-secretion drugs	0.000	0.950	0.050
I95-I99 Other and unspecified disorders of the circulatory system	0.003	0.951	0.047
I08 Multiple valve diseases	0.001	0.952	0.048
T39.0 Salicylates	0.000	0.952	0.048
I01.9 Acute rheumatic heart disease, unspecified	0.002	0.952	0.046
I01.8 Other acute rheumatic heart disease	0.002	0.952	0.046
I01.2 Acute rheumatic myocarditis	0.002	0.952	0.046
I01.1 Acute rheumatic endocarditis	0.002	0.952	0.046
I01.0 Acute rheumatic pericarditis	0.002	0.952	0.046
I02.9 Rheumatic chorea without heart involvement	0.002	0.952	0.046
I02.0 Rheumatic chorea with heart involvement	0.002	0.952	0.046
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.000	0.952	0.047
T45.9 Primarily systemic and haematological agent, unspecified	0.000	0.953	0.047
T45.8 Other primarily systemic and haematological agents	0.000	0.953	0.047
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.000	0.953	0.047
T45.6 Fibrinolysis-affecting drugs	0.000	0.953	0.047
T45.4 Iron and its compounds	0.000	0.953	0.047
T45.3 Enzymes, not elsewhere classified	0.000	0.953	0.047
I70.21 Atherosclerosis of arteries of extremities (with gangrene)	0.000	0.953	0.047
I06 Rheumatic aortic valve diseases	0.002	0.953	0.045
T45.5 Anticoagulants	0.000	0.953	0.047
I09 Other rheumatic heart diseases	0.002	0.953	0.044
T40.2 Other opioids	0.000	0.953	0.046
K44.9 Diaphragmatic hernia without obstruction or gangrene	0.000	0.954	0.046
I70.11 Atherosclerosis of renal artery (with gangrene)	0.000	0.954	0.046
J45.9 Asthma, unspecified	0.000	0.954	0.046
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.000	0.955	0.045
T47.8 Other agents primarily affecting the gastro-intestinal system	0.000	0.955	0.045
T47.7 Emetics	0.000	0.955	0.045
T47.6 Antidiarrhoeal drugs	0.000	0.955	0.045
T47.5 Digestants	0.000	0.955	0.045
T47.4 Other laxatives	0.000	0.955	0.045
T47.3 Saline and osmotic laxatives	0.000	0.955	0.045
T47.2 Stimulant laxatives	0.000	0.955	0.045
T47.0 Histamine H(2)-receptor antagonists	0.000	0.955	0.045
K57.8 Diverticular disease of intestine, part unspecified, with perforation and abscess	0.000	0.955	0.045
I08.0 Disorders of both mitral and aortic valves	0.000	0.955	0.045
I70.01 Atherosclerosis of aorta (with gangrene)	0.000	0.955	0.045
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.000	0.956	0.044
T36.0 Penicillins	0.000	0.956	0.044
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.956	0.044
T43.5 Other and unspecified antipsychotics and neuroleptics	0.000	0.956	0.043
T36.9 Systemic antibiotic, unspecified	0.000	0.957	0.043
T36.8 Other systemic antibiotics	0.000	0.957	0.043
T36.7 Antifungal antibiotics, systemically used	0.000	0.957	0.043
T36.6 Rifamycins	0.000	0.957	0.043
T36.5 Aminoglycosides	0.000	0.957	0.043
T36.4 Tetracyclines	0.000	0.957	0.043
T36.3 Macrolides	0.000	0.957	0.043
T36.2 Chloramphenicol group	0.000	0.957	0.043
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.000	0.957	0.043
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.000	0.957	0.043
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.000	0.957	0.043
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.957	0.043
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.000	0.957	0.043
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.000	0.957	0.043
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.000	0.957	0.043
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.000	0.957	0.043
T44.1 Other parasympathomimetics [cholinergics]	0.000	0.957	0.043
T44.0 Anticholinesterase agents	0.000	0.957	0.043
T43.0 Tricyclic and tetracyclic antidepressants	0.000	0.958	0.042
T46.1 Calcium-channel blockers	0.000	0.958	0.042
T41.5 Therapeutic gases	0.000	0.958	0.042
T41.4 Anaesthetic, unspecified	0.000	0.958	0.042
T41.3 Local anaesthetics	0.000	0.958	0.042
T41.2 Other and unspecified general anaesthetics	0.000	0.958	0.042
T41.1 Intravenous anaesthetics	0.000	0.958	0.042
T41.0 Inhaled anaesthetics	0.000	0.958	0.042
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.000	0.958	0.042
T48.6 Antiasthmatics, not elsewhere classified	0.000	0.958	0.042
T48.5 Anti-common-cold drugs	0.000	0.958	0.042
T48.4 Expectorants	0.000	0.958	0.042
T48.3 Antitussives	0.000	0.958	0.042
T48.2 Other and unspecified agents primarily acting on muscles	0.000	0.958	0.042
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.000	0.958	0.042
T48.0 Oxytocic drugs	0.000	0.958	0.042
T49.9 Topical agent, unspecified	0.000	0.958	0.042
T49.8 Other topical agents	0.000	0.958	0.042
T49.7 Dental drugs, topically applied	0.000	0.958	0.042
T49.6 Otorhinolaryngological drugs and preparations	0.000	0.958	0.042
T49.5 Ophthalmological drugs and preparations	0.000	0.958	0.042
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.000	0.958	0.042
T49.3 Emollients, demulcents and protectants	0.000	0.958	0.042
T49.2 Local astringents and local detergents	0.000	0.958	0.042
T49.1 Antipruritics	0.000	0.958	0.042
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.000	0.958	0.042
I07 Rheumatic tricuspid valve diseases	0.002	0.958	0.040
J44.9 Chronic obstructive pulmonary disease, unspecified	0.000	0.958	0.042
J42 Unspecified chronic bronchitis	0.000	0.958	0.042
T45.2 Vitamins, not elsewhere classified	0.000	0.958	0.041
I74.9 Embolism and thrombosis of unspecified artery	0.000	0.958	0.041
T46.4 Angiotensin-converting-enzyme inhibitors	0.000	0.959	0.041
J41 Simple and mucopurulent chronic bronchitis	0.000	0.959	0.041
T38.9 Other and unspecified hormone antagonists	0.000	0.959	0.041
T38.8 Other and unspecified hormones and their synthetic substitutes	0.000	0.959	0.041
T38.7 Androgens and anabolic congeners	0.000	0.959	0.041
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.000	0.959	0.041
T38.5 Other oestrogens and progestogens	0.000	0.959	0.041
T38.4 Oral contraceptives	0.000	0.959	0.041
T38.2 Antithyroid drugs	0.000	0.959	0.041
T38.0 Glucocorticoids and synthetic analogues	0.000	0.959	0.041
I28 Other diseases of pulmonary vessels	0.002	0.959	0.039
K57.4 Diverticular disease of both small and large intestine with perforation and abscess	0.000	0.960	0.040
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.000	0.960	0.040
T37.5 Antiviral drugs	0.000	0.960	0.040
T37.4 Anthelminthics	0.000	0.960	0.040
T37.3 Other antiprotozoal drugs	0.000	0.960	0.040
T37.2 Antimalarials and drugs acting on other blood protozoa	0.000	0.960	0.040
T37.1 Antimycobacterial drugs	0.000	0.960	0.040
T37.0 Sulphonamides	0.000	0.960	0.040
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.000	0.960	0.040
T46.8 Antivaricose drugs, including sclerosing agents	0.000	0.960	0.040
T46.7 Peripheral vasodilators	0.000	0.960	0.040
T46.5 Other antihypertensive drugs, not elsewhere classified	0.000	0.960	0.040
T46.3 Coronary vasodilators, not elsewhere classified	0.000	0.960	0.040
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.000	0.960	0.040
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.000	0.960	0.040
J09-J18 Influenza and pneumonia	0.000	0.960	0.040
Chapter X Diseases of the respiratory system	0.000	0.960	0.040
J45.8 Mixed asthma	0.000	0.961	0.039
J45.1 Nonallergic asthma	0.000	0.961	0.039
I70.10 Atherosclerosis of renal artery (without gangrene)	0.001	0.961	0.038
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.000	0.961	0.039
J80-J84 Other respiratory diseases principally affecting the interstitium	0.000	0.962	0.038
I74.5 Embolism and thrombosis of iliac artery	0.000	0.962	0.038
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.000	0.962	0.037
I74.0 Embolism and thrombosis of abdominal aorta	0.000	0.962	0.037
T43.3 Phenothiazine antipsychotics and neuroleptics	0.000	0.962	0.038
J43 Emphysema	0.000	0.962	0.038
J60-J70 Lung diseases due to external agents	0.000	0.963	0.037
T37.8 Other specified systemic anti-infectives and antiparasitics	0.000	0.963	0.037
J15 Bacterial pneumonia, not elsewhere classified	0.000	0.963	0.037
J69 Pneumonitis due to solids and liquids	0.000	0.964	0.036
I70.00 Atherosclerosis of aorta (without gangrene)	0.000	0.964	0.036
J69.0 Pneumonitis due to food and vomit	0.000	0.964	0.036
J18 Pneumonia, organism unspecified	0.000	0.964	0.036
J80 Adult respiratory distress syndrome	0.000	0.964	0.036
J18.1 Lobar pneumonia, unspecified	0.000	0.964	0.036
I99 Other and unspecified disorders of circulatory system	0.002	0.965	0.033
I08.9 Multiple valve disease, unspecified	0.001	0.965	0.034
J17 Pneumonia in diseases classified elsewhere	0.000	0.965	0.034
I27 Other pulmonary heart diseases	0.001	0.966	0.033
T38.1 Thyroid hormones and substitutes	0.000	0.966	0.034
T50.8 Diagnostic agents	0.000	0.966	0.034
T50.7 Analeptics and opioid receptor antagonists	0.000	0.966	0.034
T50.5 Appetite depressants	0.000	0.966	0.034
T50.4 Drugs affecting uric acid metabolism	0.000	0.966	0.034
T50.3 Electrolytic, caloric and water-balance agents	0.000	0.966	0.034
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.000	0.966	0.034
T50.1 Loop [high-ceiling] diuretics	0.000	0.966	0.034
T50.0 Mineralocorticoids and their antagonists	0.000	0.966	0.034
I06.9 Rheumatic aortic valve disease, unspecified	0.002	0.966	0.032
I06.8 Other rheumatic aortic valve diseases	0.002	0.966	0.032
I06.2 Rheumatic aortic stenosis with insufficiency	0.002	0.966	0.032
I06.1 Rheumatic aortic insufficiency	0.002	0.966	0.032
I06.0 Rheumatic aortic stenosis	0.002	0.966	0.032
I09.8 Other specified rheumatic heart diseases	0.002	0.966	0.032
I09.2 Chronic rheumatic pericarditis	0.002	0.966	0.032
I09.1 Rheumatic diseases of endocardium, valve unspecified	0.002	0.966	0.032
I09.0 Rheumatic myocarditis	0.002	0.966	0.032
S62 Fracture at wrist and hand level	0.000	0.966	0.034
S60-S69 Injuries to the wrist and hand	0.000	0.967	0.033
I09.9 Rheumatic heart disease, unspecified	0.002	0.967	0.031
J82 Pulmonary eosinophilia, not elsewhere classified	0.000	0.967	0.033
I08.8 Other multiple valve diseases	0.001	0.968	0.032
T50.9 Other and unspecified drugs, medicaments and biological substances	0.000	0.968	0.032
J10 Influenza due to identified influenza virus	0.000	0.968	0.032
I74.8 Embolism and thrombosis of other arteries	0.000	0.968	0.031

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations