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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs115881343
log Bayes Factor = 21.7731
Chromosome 19   position 45,403,216  (GRCh37) Explore rs115881343 on Ensembl!
Variant rs115881343 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E78.0 Pure hypercholesterolaemia
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter V Mental and behavioural disorders
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter VI Diseases of the nervous system
1.000 0.000 0.000
F00-F09 Organic, including symptomatic, mental disorders
1.000 0.000 0.000
G30-G32 Other degenerative diseases of the nervous system
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
0.999 0.001 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.999 0.001 0.000
G30 Alzheimer's disease
0.999 0.001 0.000
G30.9 Alzheimer's disease, unspecified
0.997 0.003 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.996 0.004 0.000
F03 Unspecified dementia
0.996 0.004 0.000
I60-I69 Cerebrovascular diseases
0.994 0.006 0.000
E70-E90 Metabolic disorders
0.993 0.007 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.992 0.008 0.000
G90-G99 Other disorders of the nervous system
0.990 0.010 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.990 0.010 0.000
R41.0 Disorientation, unspecified
0.989 0.011 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.988 0.012 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.988 0.012 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.983 0.017 0.000
L90 Atrophic disorders of skin
0.982 0.018 0.000
M80-M85 Disorders of bone density and structure
0.981 0.019 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.981 0.019 0.000
E78.5 Hyperlipidaemia, unspecified
0.981 0.019 0.000
L90.5 Scar conditions and fibrosis of skin
0.977 0.023 0.000
I69 Sequelae of cerebrovascular disease
0.973 0.027 0.000
I30-I52 Other forms of heart disease
0.973 0.027 0.000
F00 Dementia in Alzheimer's disease
0.970 0.030 0.000
I20-I25 Ischaemic heart diseases
0.962 0.038 0.000
L90.0 Lichen sclerosus et atrophicus
0.958 0.042 0.000
F05 Delirium, not induced by alcohol and other psychoactive substances
0.956 0.044 0.000
M40-M43 Deforming dorsopathies
0.954 0.046 0.000
R41.8 Other and unspecified symptoms and signs involving cognitive functions and awareness
0.954 0.046 0.000
F00.9 Dementia in Alzheimer's disease, unspecified
0.949 0.051 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.943 0.057 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.941 0.059 0.000
I21 Acute myocardial infarction
0.941 0.059 0.000
M81 Osteoporosis without pathological fracture
0.937 0.063 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.933 0.067 0.000
S00-S09 Injuries to the head
0.933 0.067 0.000
S40-S49 Injuries to the shoulder and upper arm
0.933 0.067 0.000
G93 Other disorders of brain
0.933 0.067 0.000
I69.3 Sequelae of cerebral infarction
0.926 0.074 0.000
M65-M68 Disorders of synovium and tendon
0.924 0.076 0.000
I46 Cardiac arrest
0.916 0.084 0.000
S70-S79 Injuries to the hip and thigh
0.915 0.085 0.000
S80-S89 Injuries to the knee and lower leg
0.915 0.085 0.000
G91 Hydrocephalus
0.914 0.086 0.000
F05.9 Delirium, unspecified
0.908 0.092 0.000
M81.9 Osteoporosis, unspecified
0.905 0.095 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.904 0.096 0.000
I49 Other cardiac arrhythmias
0.902 0.098 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.899 0.101 0.000
S42 Fracture of shoulder and upper arm
0.897 0.103 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.896 0.104 0.000
I45 Other conduction disorders
0.896 0.104 0.000
L92 Granulomatous disorders of skin and subcutaneous tissue
0.885 0.115 0.000
M65 Synovitis and tenosynovitis
0.882 0.118 0.000
S20-S29 Injuries to the thorax
0.881 0.119 0.000
G70-G73 Diseases of myoneural junction and muscle
0.875 0.125 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.874 0.126 0.000
M41 Scoliosis
0.874 0.126 0.000
Chapter XXII Codes for special purposes
0.868 0.132 0.000
I46.0 Cardiac arrest with successful resuscitation
0.866 0.134 0.000
S50-S59 Injuries to the elbow and forearm
0.865 0.135 0.000
M84 Disorders of continuity of bone
0.862 0.138 0.000
I62 Other nontraumatic intracranial haemorrhage
0.857 0.143 0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue
0.855 0.145 0.000
S82 Fracture of lower leg, including ankle
0.854 0.146 0.000
I51 Complications and ill-defined descriptions of heart disease
0.851 0.149 0.000
M43 Other deforming dorsopathies
0.851 0.149 0.000
I63 Cerebral infarction
0.848 0.152 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.843 0.157 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.842 0.158 0.000
G31.9 Degenerative disease of nervous system, unspecified
0.840 0.160 0.000
I22 Subsequent myocardial infarction
0.840 0.160 0.000
G30.8 Other Alzheimer's disease
0.840 0.160 0.000
Chapter XIV Diseases of the genitourinary system
0.839 0.161 0.000
G93.3 Postviral fatigue syndrome
0.836 0.164 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.835 0.165 0.000
I49.0 Ventricular fibrillation and flutter
0.835 0.165 0.000
F30-F39 Mood [affective] disorders
0.835 0.165 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.834 0.166 0.000
I21.9 Acute myocardial infarction, unspecified
0.834 0.166 0.000
F01 Vascular dementia
0.832 0.168 0.000
G81 Hemiplegia
0.832 0.168 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.829 0.171 0.000
G30.0 Alzheimer's disease with early onset
0.828 0.172 0.000
M81.99 Osteoporosis, unspecified (Site unspecified)
0.827 0.173 0.000
N60-N64 Disorders of breast
0.820 0.180 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.819 0.181 0.000
S06 Intracranial injury
0.819 0.181 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.819 0.181 0.000
N40-N51 Diseases of male genital organs
0.818 0.182 0.000
S42.0 Fracture of clavicle
0.818 0.182 0.000
R27 Other lack of coordination
0.818 0.182 0.000
S00 Superficial injury of head
0.818 0.182 0.000
R20 Disturbances of skin sensation
0.817 0.183 0.000
M81.90 Osteoporosis, unspecified (Multiple sites)
0.817 0.183 0.000
M41.9 Scoliosis, unspecified
0.817 0.183 0.000
E40-E46 Malnutrition
0.816 0.184 0.000
M80 Osteoporosis with pathological fracture
0.814 0.186 0.000
G91.9 Hydrocephalus, unspecified
0.813 0.187 0.000
M65.9 Synovitis and tenosynovitis, unspecified
0.813 0.187 0.000
I45.1 Other and unspecified right bundle-branch block
0.812 0.188 0.000
M86-M90 Other osteopathies
0.811 0.189 0.000
Chapter XX External causes of morbidity and mortality
0.808 0.192 0.000
S05 Injury of eye and orbit
0.806 0.194 0.000
R22.1 Localised swelling, mass and lump, neck
0.805 0.195 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.803 0.197 0.000
S72 Fracture of femur
0.801 0.199 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.801 0.199 0.000
F02 Dementia in other diseases classified elsewhere
0.799 0.200 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.798 0.202 0.000
G31.0 Circumscribed brain atrophy
0.797 0.203 0.000
N45 Orchitis and epididymitis
0.796 0.204 0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.794 0.206 0.000
G93.8 Other specified disorders of brain
0.793 0.207 0.000
L92.9 Granulomatous disorder of skin and subcutaneous tissue, unspecified
0.793 0.207 0.000
R23 Other skin changes
0.789 0.211 0.000
G81.9 Hemiplegia, unspecified
0.786 0.214 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.781 0.219 0.000
N45.9 Orchitis, epididymitis and epididymo-orchitis without abscess
0.780 0.220 0.000
G40-G47 Episodic and paroxysmal disorders
0.780 0.220 0.000
S32 Fracture of lumbar spine and pelvis
0.780 0.220 0.000
L50-L54 Urticaria and erythema
0.779 0.221 0.000
L85 Other epidermal thickening
0.778 0.222 0.000
M43.1 Spondylolisthesis
0.778 0.222 0.000
F05.8 Other delirium
0.777 0.223 0.000
S42.2 Fracture of upper end of humerus
0.777 0.223 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.777 0.223 0.000
G70 Myasthenia gravis and other myoneural disorders
0.775 0.225 0.000
N50 Other disorders of male genital organs
0.774 0.226 0.000
G91.0 Communicating hydrocephalus
0.773 0.227 0.000
M60-M63 Disorders of muscles
0.771 0.228 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.771 0.229 0.000
R41.2 Retrograde amnesia
0.771 0.229 0.000
I67 Other cerebrovascular diseases
0.771 0.229 0.000
N60 Benign mammary dysplasia
0.771 0.229 0.000
L84 Corns and callosities
0.770 0.230 0.000
R46 Symptoms and signs involving appearance and behaviour
0.767 0.233 0.000
S70 Superficial injury of hip and thigh
0.767 0.233 0.000
R41.3 Other amnesia
0.766 0.234 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.764 0.236 0.000
L20-L30 Dermatitis and eczema
0.764 0.236 0.000
S60-S69 Injuries to the wrist and hand
0.763 0.237 0.000
S42.00 Fracture of clavicle (closed)
0.762 0.238 0.000
S82.2 Fracture of shaft of tibia
0.762 0.238 0.000
S90-S99 Injuries to the ankle and foot
0.761 0.239 0.000
R27.0 Ataxia, unspecified
0.756 0.244 0.000
R22.4 Localised swelling, mass and lump, lower limb
0.755 0.245 0.000
S42.1 Fracture of scapula
0.753 0.247 0.000
S10-S19 Injuries to the neck
0.753 0.247 0.000
M65.4 Radial styloid tenosynovitis [de Quervain]
0.752 0.248 0.000
M91-M94 Chondropathies
0.752 0.248 0.000
E50-E64 Other nutritional deficiencies
0.751 0.249 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.750 0.250 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.748 0.252 0.000
F43 Reaction to severe stress, and adjustment disorders
0.748 0.252 0.000
I47 Paroxysmal tachycardia
0.746 0.254 0.000
I49.8 Other specified cardiac arrhythmias
0.746 0.254 0.000
S20 Superficial injury of thorax
0.746 0.254 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.745 0.255 0.000
R20.2 Paraesthesia of skin
0.744 0.256 0.000
I49.3 Ventricular premature depolarisation
0.743 0.257 0.000
I60 Subarachnoid haemorrhage
0.742 0.258 0.000
R25 Abnormal involuntary movements
0.741 0.259 0.000
G95 Other diseases of spinal cord
0.741 0.259 0.000
I45.5 Other specified heart block
0.741 0.259 0.000
L93 Lupus erythematosus
0.735 0.265 0.000
F33 Recurrent depressive disorder
0.734 0.266 0.000
G31.8 Other specified degenerative diseases of nervous system
0.734 0.266 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.733 0.267 0.000
I63.9 Cerebral infarction, unspecified
0.730 0.270 0.000
I33 Acute and subacute endocarditis
0.729 0.271 0.000
L83 Acanthosis nigricans
0.729 0.271 0.000
R45 Symptoms and signs involving emotional state
0.728 0.272 0.000
I62.9 Intracranial haemorrhage (nontraumatic), unspecified
0.727 0.273 0.000
N41 Inflammatory diseases of prostate
0.726 0.274 0.000
F80-F89 Disorders of psychological development
0.725 0.275 0.000
F99-F99 Unspecified mental disorder
0.724 0.275 0.000
M85 Other disorders of bone density and structure
0.723 0.277 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.723 0.277 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.721 0.279 0.000
T39.1 4-Aminophenol derivatives
0.721 0.279 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.720 0.280 0.000
S00.8 Superficial injury of other parts of head
0.719 0.281 0.000
M65.91 Synovitis and tenosynovitis, unspecified (Shoulder region)
0.718 0.282 0.000
G93.0 Cerebral cysts
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.717 0.283 0.000
F70-F79 Mental retardation
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction
0.717 0.283 0.000
F09 Unspecified organic or symptomatic mental disorder
0.717 0.283 0.000
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances
0.717 0.283 0.000
G32 Other degenerative disorders of nervous system in diseases classified elsewhere
0.717 0.283 0.000
M41.95 Scoliosis, unspecified (Thoracolumbar region)
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
E78.6 Lipoprotein deficiency
0.716 0.283 0.000
E78.4 Other hyperlipidaemia
0.716 0.283 0.000
E78.3 Hyperchylomicronaemia
0.716 0.283 0.000
E78.1 Pure hyperglyceridaemia
0.716 0.283 0.000
G30.1 Alzheimer's disease with late onset
0.716 0.284 0.000
I49.4 Other and unspecified premature depolarisation
0.716 0.284 0.000
S05.8 Other injuries of eye and orbit
0.716 0.284 0.000
G96 Other disorders of central nervous system
0.715 0.285 0.000
I30 Acute pericarditis
0.714 0.285 0.000
M00-M03 Infectious arthropathies
0.714 0.286 0.000
L89 Decubitus ulcer
0.714 0.286 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.714 0.286 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.714 0.286 0.000
S82.1 Fracture of upper end of tibia
0.713 0.287 0.000
I27 Other pulmonary heart diseases
0.712 0.287 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.712 0.288 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.712 0.288 0.000
F01.9 Vascular dementia, unspecified
0.712 0.288 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.712 0.288 0.000
E85 Amyloidosis
0.712 0.288 0.000
E84 Cystic fibrosis
0.712 0.288 0.000
E79 Disorders of purine and pyrimidine metabolism
0.712 0.288 0.000
E77 Disorders of glycoprotein metabolism
0.712 0.288 0.000
E76 Disorders of glycosaminoglycan metabolism
0.712 0.288 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.712 0.288 0.000
E74 Other disorders of carbohydrate metabolism
0.712 0.288 0.000
E73 Lactose intolerance
0.712 0.288 0.000
E72 Other disorders of amino-acid metabolism
0.712 0.288 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.712 0.288 0.000
E70 Disorders of aromatic amino-acid metabolism
0.712 0.288 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.712 0.288 0.000
N61 Inflammatory disorders of breast
0.711 0.289 0.000
N50.8 Other specified disorders of male genital organs
0.711 0.289 0.000
S06.0 Concussion
0.711 0.289 0.000
I25 Chronic ischaemic heart disease
0.711 0.289 0.000
S72.1 Pertrochanteric fracture
0.711 0.289 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.710 0.290 0.000
G90 Disorders of autonomic nervous system
0.710 0.290 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.710 0.290 0.000
G92 Toxic encephalopathy
0.710 0.290 0.000
R41.1 Anterograde amnesia
0.710 0.290 0.000
M43.16 Spondylolisthesis (Lumbar region)
0.710 0.290 0.000
L92.0 Granuloma annulare
0.710 0.290 0.000
I46.9 Cardiac arrest, unspecified
0.709 0.291 0.000
M65.1 Other infective (teno)synovitis
0.708 0.292 0.000
R43 Disturbances of smell and taste
0.708 0.292 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.708 0.292 0.000
S42.9 Fracture of shoulder girdle, part unspecified
0.706 0.294 0.000
S51 Open wound of forearm
0.705 0.295 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.705 0.295 0.000
I69.0 Sequelae of subarachnoid haemorrhage
0.705 0.295 0.000
L10-L14 Bullous disorders
0.705 0.295 0.000
L90.9 Atrophic disorder of skin, unspecified
0.704 0.296 0.000
L90.8 Other atrophic disorders of skin
0.704 0.296 0.000
L90.6 Striae atrophicae
0.704 0.296 0.000
L90.4 Acrodermatitis chronica atrophicans
0.704 0.296 0.000
L90.3 Atrophoderma of Pasini and Pierini
0.704 0.296 0.000
L90.2 Anetoderma of Jadassohn-Pellizzari
0.704 0.296 0.000
L90.1 Anetoderma of Schweninger-Buzzi
0.704 0.296 0.000
G70.0 Myasthenia gravis
0.704 0.296 0.000
M83 Adult osteomalacia
0.704 0.296 0.000
M82 Osteoporosis in diseases classified elsewhere
0.704 0.296 0.000
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.703 0.296 0.000
L95 Vasculitis limited to skin, not elsewhere classified
0.703 0.296 0.000
L94 Other localised connective tissue disorders
0.703 0.296 0.000
L87 Transepidermal elimination disorders
0.703 0.296 0.000
L88 Pyoderma gangrenosum
0.703 0.296 0.000
L86 Keratoderma in diseases classified elsewhere
0.703 0.296 0.000
L80 Vitiligo
0.703 0.296 0.000
T39.0 Salicylates
0.703 0.297 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.702 0.298 0.000
E78.8 Other disorders of lipoprotein metabolism
0.702 0.298 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.701 0.299 0.000
E78.9 Disorder of lipoprotein metabolism, unspecified
0.701 0.299 0.000
F60-F69 Disorders of adult personality and behaviour
0.700 0.300 0.000
G93.1 Anoxic brain damage, not elsewhere classified
0.700 0.300 0.000
N60.0 Solitary cyst of breast
0.699 0.301 0.000
I47.2 Ventricular tachycardia
0.698 0.301 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.698 0.302 0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.697 0.303 0.000
I69.1 Sequelae of intracerebral haemorrhage
0.697 0.303 0.000
I52 Other heart disorders in diseases classified elsewhere
0.697 0.303 0.000
I48 Atrial fibrillation and flutter
0.697 0.303 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.697 0.303 0.000
I41 Myocarditis in diseases classified elsewhere
0.697 0.303 0.000
I40 Acute myocarditis
0.697 0.303 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.697 0.303 0.000
I37 Pulmonary valve disorders
0.697 0.303 0.000
I36 Nonrheumatic tricuspid valve disorders
0.697 0.303 0.000
I32 Pericarditis in diseases classified elsewhere
0.697 0.303 0.000
S80 Superficial injury of lower leg
0.697 0.303 0.000
T79-T79 Certain early complications of trauma
0.697 0.303 0.000
M41.99 Scoliosis, unspecified (Site unspecified)
0.696 0.304 0.000
F00.2 Dementia in Alzheimer's disease, atypical or mixed type
0.696 0.304 0.000
F00.1 Dementia in Alzheimer's disease with late onset
0.696 0.304 0.000
F00.0 Dementia in Alzheimer's disease with early onset
0.696 0.304 0.000
L29 Pruritus
0.695 0.305 0.000
S82.4 Fracture of fibula alone
0.695 0.305 0.000
N10-N16 Renal tubulo-interstitial diseases
0.695 0.305 0.000
G40 Epilepsy
0.695 0.305 0.000
S27 Injury of other and unspecified intrathoracic organs
0.694 0.306 0.000
I51.4 Myocarditis, unspecified
0.694 0.306 0.000
M65.8 Other synovitis and tenosynovitis
0.693 0.307 0.000
I63.8 Other cerebral infarction
0.693 0.307 0.000
N60.2 Fibroadenosis of breast
0.691 0.308 0.000
S42.20 Fracture of upper end of humerus (closed)
0.691 0.309 0.000
I22.1 Subsequent myocardial infarction of inferior wall
0.691 0.309 0.000
T18 Foreign body in alimentary tract
0.690 0.310 0.000
I23 Certain current complications following acute myocardial infarction
0.689 0.310 0.000
E46 Unspecified protein-energy malnutrition
0.689 0.311 0.000
T51 Toxic effect of alcohol
0.689 0.311 0.000
M81.98 Osteoporosis, unspecified (Other)
0.689 0.311 0.000
E88 Other metabolic disorders
0.689 0.311 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.686 0.314 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.686 0.314 0.000
W00-W19 Falls
0.686 0.314 0.000
F05.1 Delirium superimposed on dementia
0.685 0.314 0.000
F05.0 Delirium not superimposed on dementia, so described
0.685 0.314 0.000
S56 Injury of muscle and tendon at forearm level
0.684 0.316 0.000
I05-I09 Chronic rheumatic heart diseases
0.684 0.316 0.000
M42 Spinal osteochondrosis
0.684 0.316 0.000
M40 Kyphosis and lordosis
0.684 0.316 0.000
I51.6 Cardiovascular disease, unspecified
0.682 0.318 0.000
S81 Open wound of lower leg
0.680 0.320 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.679 0.321 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.679 0.321 0.000
F10.3 Withdrawal state
0.679 0.321 0.000
T66-T78 Other and unspecified effects of external causes
0.677 0.322 0.000
L81 Other disorders of pigmentation
0.677 0.323 0.000
S40 Superficial injury of shoulder and upper arm
0.675 0.325 0.000
S79 Other and unspecified injuries of hip and thigh
0.675 0.325 0.000
V20-V29 Motorcycle rider injured in transport accident
0.675 0.325 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.675 0.325 0.000
G31.2 Degeneration of nervous system due to alcohol
0.674 0.325 0.000
G31.1 Senile degeneration of brain, not elsewhere classified
0.674 0.325 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.674 0.325 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.674 0.325 0.000
I62.0 Subdural haemorrhage (acute) (nontraumatic)
0.674 0.326 0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.674 0.326 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.674 0.326 0.000
S52 Fracture of forearm
0.673 0.327 0.000
I44 Atrioventricular and left bundle-branch block
0.673 0.327 0.000
S00.7 Multiple superficial injuries of head
0.672 0.328 0.000
M81.8 Other osteoporosis
0.672 0.328 0.000
M81.6 Localised osteoporosis [Lequesne]
0.672 0.328 0.000
M81.5 Idiopathic osteoporosis
0.672 0.328 0.000
M81.4 Drug-induced osteoporosis
0.672 0.328 0.000
M81.3 Postsurgical malabsorption osteoporosis
0.672 0.328 0.000
M81.2 Osteoporosis of disuse
0.672 0.328 0.000
M81.1 Postoophorectomy osteoporosis
0.672 0.328 0.000
M81.0 Postmenopausal osteoporosis
0.672 0.328 0.000
S89 Other and unspecified injuries of lower leg
0.672 0.328 0.000
M70-M79 Other soft tissue disorders
0.671 0.329 0.000
M65.96 Synovitis and tenosynovitis, unspecified (Lower leg)
0.671 0.329 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.670 0.330 0.000
N62 Hypertrophy of breast
0.670 0.330 0.000
S32.7 Multiple fractures of lumbar spine and pelvis
0.669 0.331 0.000
S08 Traumatic amputation of part of head
0.669 0.331 0.000
S07 Crushing injury of head
0.669 0.331 0.000
S04 Injury of cranial nerves
0.669 0.331 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.669 0.331 0.000
S48 Traumatic amputation of shoulder and upper arm
0.669 0.331 0.000
S45 Injury of blood vessels at shoulder and upper arm level
0.669 0.331 0.000
S44 Injury of nerves at shoulder and upper arm level
0.669 0.331 0.000
S41 Open wound of shoulder and upper arm
0.669 0.331 0.000
S47 Crushing injury of shoulder and upper arm
0.669 0.331 0.000
G93.7 Reye's syndrome
0.669 0.331 0.000
G93.5 Compression of brain
0.669 0.331 0.000
G93.2 Benign intracranial hypertension
0.669 0.331 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.668 0.332 0.000
N99-N99 Other disorders of the genitourinary system
0.667 0.333 0.000
T63 Toxic effect of contact with venomous animals
0.665 0.335 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.665 0.335 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.665 0.335 0.000
S82.21 Fracture of shaft of tibia (open)
0.664 0.336 0.000
M50-M54 Other dorsopathies
0.664 0.336 0.000
E86 Volume depletion
0.663 0.337 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.662 0.338 0.000
M66 Spontaneous rupture of synovium and tendon
0.662 0.338 0.000
S70.9 Superficial injury of hip and thigh, unspecified
0.661 0.339 0.000
I22.0 Subsequent myocardial infarction of anterior wall
0.660 0.339 0.000
G93.4 Encephalopathy, unspecified
0.660 0.340 0.000
G93.6 Cerebral oedema
0.659 0.341 0.000
M65.43 Radial styloid tenosynovitis [de Quervain] (Forearm)
0.659 0.341 0.000
E78.2 Mixed hyperlipidaemia
0.658 0.342 0.000
I46.1 Sudden cardiac death, so described
0.657 0.343 0.000
L85.8 Other specified epidermal thickening
0.657 0.343 0.000
S78 Traumatic amputation of hip and thigh
0.656 0.344 0.000
S77 Crushing injury of hip and thigh
0.656 0.344 0.000
S76 Injury of muscle and tendon at hip and thigh level
0.656 0.344 0.000
S75 Injury of blood vessels at hip and thigh level
0.656 0.344 0.000
S74 Injury of nerves at hip and thigh level
0.656 0.344 0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip
0.656 0.344 0.000
S71 Open wound of hip and thigh
0.656 0.344 0.000
S88 Traumatic amputation of lower leg
0.656 0.344 0.000
S87 Crushing injury of lower leg
0.656 0.344 0.000
S86 Injury of muscle and tendon at lower leg level
0.656 0.344 0.000
S85 Injury of blood vessels at lower leg level
0.656 0.344 0.000
S84 Injury of nerves at lower leg level
0.656 0.344 0.000
F02.0 Dementia in Pick's disease
0.656 0.344 0.000
G80 Infantile cerebral palsy
0.655 0.345 0.000
G91.8 Other hydrocephalus
0.655 0.345 0.000
G91.3 Posttraumatic hydrocephalus, unspecified
0.655 0.345 0.000
G91.2 Normal-pressure hydrocephalus
0.655 0.345 0.000
G91.1 Obstructive hydrocephalus
0.655 0.345 0.000
G99.0 Autonomic neuropathy in endocrine and metabolic diseases
0.655 0.345 0.000
G93.9 Disorder of brain, unspecified
0.655 0.345 0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease
0.652 0.348 0.000
G72 Other myopathies
0.652 0.348 0.000
F52 Sexual dysfunction, not caused by organic disorder or disease
0.651 0.349 0.000
S42.10 Fracture of scapula (closed)
0.650 0.349 0.000
I51.7 Cardiomegaly
0.650 0.350 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.649 0.351 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.649 0.351 0.000
M81.97 Osteoporosis, unspecified (Ankle and foot)
0.649 0.351 0.000
M81.96 Osteoporosis, unspecified (Lower leg)
0.649 0.351 0.000
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)
0.649 0.351 0.000
M81.94 Osteoporosis, unspecified (Hand)
0.649 0.351 0.000
M81.93 Osteoporosis, unspecified (Forearm)
0.649 0.351 0.000
M81.92 Osteoporosis, unspecified (Upper arm)
0.649 0.351 0.000
M81.91 Osteoporosis, unspecified (Shoulder region)
0.649 0.351 0.000
M80.1 Postoophorectomy osteoporosis with pathological fracture
0.649 0.351 0.000
S82.3 Fracture of lower end of tibia
0.648 0.352 0.000
S02 Fracture of skull and facial bones
0.647 0.353 0.000
I49.1 Atrial premature depolarisation
0.647 0.353 0.000
I49.2 Junctional premature depolarisation
0.646 0.354 0.000
S72.10 Pertrochanteric fracture (closed)
0.646 0.354 0.000
S20.2 Contusion of thorax
0.645 0.355 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.644 0.355 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.644 0.355 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.644 0.355 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.644 0.355 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.644 0.355 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.644 0.355 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.644 0.355 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.644 0.355 0.000
T36 Poisoning by systemic antibiotics
0.644 0.355 0.000
S42.8 Fracture of other parts of shoulder and upper arm
0.643 0.357 0.000
S42.7 Multiple fractures of clavicle, scapula and humerus
0.643 0.357 0.000
G83 Other paralytic syndromes
0.643 0.357 0.000
I45.9 Conduction disorder, unspecified
0.642 0.358 0.000
I45.8 Other specified conduction disorders
0.642 0.358 0.000
I45.4 Nonspecific intraventricular block
0.642 0.358 0.000
I45.3 Trifascicular block
0.642 0.358 0.000
I45.2 Bifascicular block
0.642 0.358 0.000
I45.0 Right fascicular block
0.642 0.358 0.000
F50 Eating disorders
0.642 0.358 0.000
I61 Intracerebral haemorrhage
0.641 0.359 0.000
M65.97 Synovitis and tenosynovitis, unspecified (Ankle and foot)
0.640 0.360 0.000
R30-R39 Symptoms and signs involving the urinary system
0.639 0.361 0.000
R22.9 Localised swelling, mass and lump, unspecified
0.639 0.361 0.000
M80.9 Unspecified osteoporosis with pathological fracture
0.638 0.362 0.000
M87 Osteonecrosis
0.638 0.362 0.000
I25.2 Old myocardial infarction
0.637 0.363 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.637 0.363 0.000
N41.1 Chronic prostatitis
0.637 0.363 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.637 0.363 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.637 0.363 0.000
S06.2 Diffuse brain injury
0.636 0.364 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.635 0.365 0.000
I22.8 Subsequent myocardial infarction of other sites
0.635 0.365 0.000
L92.8 Other granulomatous disorders of skin and subcutaneous tissue
0.634 0.366 0.000
L92.2 Granuloma faciale [eosinophilic granuloma of skin]
0.634 0.366 0.000
L92.1 Necrobiosis lipoidica, not elsewhere classified
0.634 0.366 0.000
M41.96 Scoliosis, unspecified (Lumbar region)
0.634 0.366 0.000
R23.8 Other and unspecified skin changes
0.634 0.366 0.000
S06.00 Concussion (without open intracranial wound)
0.633 0.367 0.000
E87.0 Hyperosmolality and hypernatraemia
0.633 0.367 0.000
M65.2 Calcific tendinitis
0.632 0.367 0.000
M65.0 Abscess of tendon sheath
0.632 0.367 0.000
N60.1 Diffuse cystic mastopathy
0.632 0.368 0.000
L60-L75 Disorders of skin appendages
0.632 0.368 0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax
0.631 0.368 0.000
S26 Injury of heart
0.631 0.368 0.000
S25 Injury of blood vessels of thorax
0.631 0.368 0.000
S24 Injury of nerves and spinal cord at thorax level
0.631 0.368 0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax
0.631 0.368 0.000
S21 Open wound of thorax
0.631 0.368 0.000
U51 Admission status on psychiatric patients
0.631 0.369 0.000
M84.0 Malunion of fracture
0.630 0.369 0.000
T40.2 Other opioids
0.630 0.369 0.000
M84.13 Nonunion of fracture [pseudarthrosis] (Forearm)
0.630 0.370 0.000
R23.2 Flushing
0.629 0.371 0.000
I51.9 Heart disease, unspecified
0.627 0.373 0.000
G73 Disorders of myoneural junction and muscle in diseases classified elsewhere
0.627 0.373 0.000
G71 Primary disorders of muscles
0.627 0.373 0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis
0.627 0.373 0.000
S37 Injury of urinary and pelvic organs
0.627 0.373 0.000
S36 Injury of intra-abdominal organs
0.627 0.373 0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level
0.627 0.373 0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level
0.627 0.373 0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis
0.627 0.373 0.000
S31 Open wound of abdomen, lower back and pelvis
0.627 0.373 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.627 0.373 0.000
L29.9 Pruritus, unspecified
0.627 0.373 0.000
M41.8 Other forms of scoliosis
0.626 0.373 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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