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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs116044577
log Bayes Factor = 12.8773
Chromosome 3   position 173,023,621  (GRCh37) Explore rs116044577 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XV Pregnancy, childbirth and the puerperium
1.000 0.000 0.000
Chapter VI Diseases of the nervous system
0.998 0.002 0.000
M20-M25 Other joint disorders
0.998 0.002 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.998 0.002 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.997 0.003 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.989 0.011 0.000
O60-O75 Complications of labour and delivery
0.989 0.011 0.000
S00-S09 Injuries to the head
0.979 0.021 0.000
M45-M49 Spondylopathies
0.978 0.022 0.000
G55.1 Nerve root and plexus compressions in intervertebral disk disorders
0.977 0.023 0.000
M23 Internal derangement of knee
0.974 0.026 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.963 0.037 0.000
Chapter XIV Diseases of the genitourinary system
0.960 0.040 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.957 0.043 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.950 0.050 0.000
N17-N19 Renal failure
0.949 0.051 0.000
G57 Mononeuropathies of lower limb
0.945 0.055 0.000
Chapter XXI Factors influencing health status and contact with health services
0.943 0.057 0.000
M48 Other spondylopathies
0.940 0.060 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.935 0.065 0.000
S01 Open wound of head
0.933 0.067 0.000
N17 Acute renal failure
0.928 0.072 0.000
Z60 Problems related to social environment
0.927 0.073 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.926 0.074 0.000
Z60.2 Living alone
0.922 0.078 0.000
T39.1 4-Aminophenol derivatives
0.919 0.081 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.916 0.084 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.915 0.085 0.000
M22 Disorders of patella
0.914 0.086 0.000
N17.9 Acute renal failure, unspecified
0.913 0.087 0.000
M48.0 Spinal stenosis
0.912 0.088 0.000
M05-M14 Inflammatory polyarthropathies
0.911 0.089 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.910 0.090 0.000
S00 Superficial injury of head
0.910 0.090 0.000
S60-S69 Injuries to the wrist and hand
0.908 0.092 0.000
G57.6 Lesion of plantar nerve
0.907 0.093 0.000
M24 Other specific joint derangements
0.906 0.094 0.000
O42 Premature rupture of membranes
0.903 0.097 0.000
N60-N64 Disorders of breast
0.902 0.098 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.900 0.100 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.900 0.100 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.898 0.102 0.000
O16 Unspecified maternal hypertension
0.894 0.106 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.894 0.106 0.000
Chapter V Mental and behavioural disorders
0.892 0.108 0.000
N18 Chronic renal failure
0.890 0.110 0.000
M50-M54 Other dorsopathies
0.890 0.110 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.882 0.118 0.000
Chapter XI Diseases of the digestive system
0.881 0.119 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.881 0.119 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.878 0.122 0.000
M23.3 Other meniscus derangements
0.876 0.124 0.000
O72 Postpartum haemorrhage
0.874 0.126 0.000
M40-M43 Deforming dorsopathies
0.872 0.128 0.000
K80 Cholelithiasis
0.868 0.132 0.000
M47 Spondylosis
0.866 0.134 0.000
N18.3 Chronic kidney disease, stage 3
0.863 0.137 0.000
S80-S89 Injuries to the knee and lower leg
0.860 0.140 0.000
S32 Fracture of lumbar spine and pelvis
0.859 0.141 0.000
K80.1 Calculus of gallbladder with other cholecystitis
0.855 0.145 0.000
G90-G99 Other disorders of the nervous system
0.854 0.146 0.000
M80-M85 Disorders of bone density and structure
0.852 0.148 0.000
M25 Other joint disorders, not elsewhere classified
0.851 0.149 0.000
K82 Other diseases of gallbladder
0.847 0.153 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.842 0.158 0.000
O80-O84 Delivery
0.840 0.160 0.000
M48.06 Spinal stenosis (Lumbar region)
0.839 0.161 0.000
S20-S29 Injuries to the thorax
0.839 0.161 0.000
K50-K52 Noninfective enteritis and colitis
0.835 0.165 0.000
O66 Other obstructed labour
0.834 0.166 0.000
N64 Other disorders of breast
0.829 0.171 0.000
M06 Other rheumatoid arthritis
0.829 0.171 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.828 0.171 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.828 0.172 0.000
M23.23 Derangement of meniscus due to old tear or injury (Medial collateral ligament or Other and unspecified medial meniscus)
0.828 0.172 0.000
T39.0 Salicylates
0.827 0.173 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.826 0.174 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.826 0.174 0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria
0.825 0.175 0.000
M48.07 Spinal stenosis (Lumbosacral region)
0.825 0.175 0.000
M21 Other acquired deformities of limbs
0.824 0.176 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.824 0.176 0.000
Z35 Supervision of high-risk pregnancy
0.824 0.176 0.000
Z37 Outcome of delivery
0.823 0.177 0.000
S01.5 Open wound of lip and oral cavity
0.820 0.180 0.000
O70 Perineal laceration during delivery
0.818 0.182 0.000
Z63 Other problems related to primary support group, including family circumstances
0.818 0.182 0.000
N93 Other abnormal uterine and vaginal bleeding
0.816 0.184 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.815 0.185 0.000
G55.3 Nerve root and plexus compressions in other dorsopathies
0.813 0.187 0.000
Q80-Q89 Other congenital malformations
0.812 0.187 0.000
M23.8 Other internal derangements of knee
0.812 0.188 0.000
K82.8 Other specified diseases of gallbladder
0.812 0.188 0.000
N93.8 Other specified abnormal uterine and vaginal bleeding
0.809 0.191 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.808 0.192 0.000
K51 Ulcerative colitis
0.806 0.194 0.000
O42.9 Premature rupture of membranes, unspecified
0.804 0.196 0.000
S01.0 Open wound of scalp
0.803 0.197 0.000
M54 Dorsalgia
0.801 0.199 0.000
O75.8 Other specified complications of labour and delivery
0.798 0.202 0.000
K80.4 Calculus of bile duct with cholecystitis
0.794 0.206 0.000
F30-F39 Mood [affective] disorders
0.794 0.206 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.794 0.206 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.792 0.208 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.791 0.208 0.000
T51 Toxic effect of alcohol
0.791 0.209 0.000
Chapter VIII Diseases of the ear and mastoid process
0.790 0.210 0.000
Chapter XX External causes of morbidity and mortality
0.789 0.211 0.000
O47 False labour
0.788 0.212 0.000
M24.1 Other articular cartilage disorders
0.788 0.212 0.000
M22.4 Chondromalacia patellae
0.787 0.213 0.000
S50-S59 Injuries to the elbow and forearm
0.786 0.214 0.000
Chapter XXII Codes for special purposes
0.786 0.214 0.000
G63.2 Diabetic polyneuropathy
0.786 0.214 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.785 0.215 0.000
T66-T78 Other and unspecified effects of external causes
0.784 0.216 0.000
M86-M90 Other osteopathies
0.782 0.218 0.000
M84 Disorders of continuity of bone
0.782 0.218 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.777 0.223 0.000
G55.2 Nerve root and plexus compressions in spondylosis
0.777 0.223 0.000
N64.9 Disorder of breast, unspecified
0.777 0.223 0.000
T43.2 Other and unspecified antidepressants
0.776 0.224 0.000
S90-S99 Injuries to the ankle and foot
0.771 0.229 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.769 0.231 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.766 0.234 0.000
M47.2 Other spondylosis with radiculopathy
0.765 0.235 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.764 0.236 0.000
Z37.0 Single live birth
0.764 0.236 0.000
M22.8 Other disorders of patella
0.763 0.237 0.000
O42.0 Premature rupture of membranes, onset of labour within 24 hours
0.760 0.240 0.000
M60-M63 Disorders of muscles
0.759 0.241 0.000
M06.9 Rheumatoid arthritis, unspecified
0.758 0.242 0.000
S01.9 Open wound of head, part unspecified
0.757 0.243 0.000
O63 Long labour
0.756 0.244 0.000
S00.1 Contusion of eyelid and periocular area
0.755 0.244 0.000
M23.22 Derangement of meniscus due to old tear or injury (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.753 0.247 0.000
N20-N23 Urolithiasis
0.753 0.247 0.000
M34 Systemic sclerosis
0.752 0.248 0.000
S00.0 Superficial injury of scalp
0.751 0.249 0.000
N63 Unspecified lump in breast
0.751 0.249 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.748 0.252 0.000
G54 Nerve root and plexus disorders
0.748 0.252 0.000
M91-M94 Chondropathies
0.748 0.252 0.000
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.747 0.253 0.000
T93 Sequelae of injuries of lower limb
0.747 0.253 0.000
O42.1 Premature rupture of membranes, onset of labour after 24 hours
0.746 0.254 0.000
M48.00 Spinal stenosis (Multiple sites in spine)
0.746 0.254 0.000
M25.3 Other instability of joint
0.744 0.256 0.000
G50 Disorders of trigeminal nerve
0.741 0.259 0.000
S70-S79 Injuries to the hip and thigh
0.740 0.259 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.739 0.261 0.000
G93 Other disorders of brain
0.738 0.261 0.000
M50 Cervical disk disorders
0.738 0.262 0.000
M45 Ankylosing spondylitis
0.738 0.262 0.000
S62 Fracture at wrist and hand level
0.738 0.262 0.000
Z34 Supervision of normal pregnancy
0.737 0.263 0.000
O72.1 Other immediate postpartum haemorrhage
0.736 0.264 0.000
S60 Superficial injury of wrist and hand
0.736 0.264 0.000
T56 Toxic effect of metals
0.735 0.265 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.733 0.267 0.000
S05 Injury of eye and orbit
0.732 0.268 0.000
M43 Other deforming dorsopathies
0.730 0.270 0.000
S64 Injury of nerves at wrist and hand level
0.729 0.271 0.000
M15-M19 Arthrosis
0.729 0.271 0.000
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium
0.728 0.272 0.000
F31 Bipolar affective disorder
0.728 0.272 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.727 0.273 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.726 0.274 0.000
O62 Abnormalities of forces of labour
0.726 0.274 0.000
G20-G26 Extrapyramidal and movement disorders
0.726 0.274 0.000
O82 Single delivery by Caesarean section
0.726 0.274 0.000
T59 Toxic effect of other gases, fumes and vapours
0.725 0.275 0.000
M24.2 Disorder of ligament
0.725 0.275 0.000
O75.7 Vaginal delivery following previous Caesarean section
0.724 0.276 0.000
O66.5 Failed application of vacuum extractor and forceps, unspecified
0.723 0.276 0.000
O72.0 Third-stage haemorrhage
0.723 0.277 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.722 0.277 0.000
O70.1 Second degree perineal laceration during delivery
0.722 0.278 0.000
S02 Fracture of skull and facial bones
0.722 0.278 0.000
K51.2 Ulcerative (chronic) proctitis
0.721 0.279 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.721 0.279 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.721 0.279 0.000
S40-S49 Injuries to the shoulder and upper arm
0.719 0.281 0.000
G58 Other mononeuropathies
0.718 0.282 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
S10-S19 Injuries to the neck
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
O85-O92 Complications predominantly related to the puerperium
0.717 0.283 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.717 0.283 0.000
O36 Maternal care for other known or suspected foetal problems
0.717 0.283 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.716 0.284 0.000
N60 Benign mammary dysplasia
0.716 0.284 0.000
M24.0 Loose body in joint
0.716 0.284 0.000
G70-G73 Diseases of myoneural junction and muscle
0.716 0.284 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.716 0.284 0.000
M33 Dermatopolymyositis
0.716 0.284 0.000
M32 Systemic lupus erythematosus
0.716 0.284 0.000
M30 Polyarteritis nodosa and related conditions
0.716 0.284 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.715 0.284 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.715 0.284 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.715 0.284 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.715 0.284 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.715 0.284 0.000
T36 Poisoning by systemic antibiotics
0.715 0.284 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.714 0.285 0.000
G52 Disorders of other cranial nerves
0.714 0.285 0.000
M23.39 Other meniscus derangements (Unspecified ligament or Unspecified meniscus)
0.714 0.286 0.000
M35 Other systemic involvement of connective tissue
0.714 0.286 0.000
M11 Other crystal arthropathies
0.714 0.286 0.000
N94 Pain and other conditions associated with female genital organs and menstrual cycle
0.714 0.286 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.714 0.286 0.000
Z35.1 Supervision of pregnancy with history of abortive outcome
0.713 0.287 0.000
M41 Scoliosis
0.713 0.287 0.000
G55.0 Nerve root and plexus compressions in neoplastic disease
0.712 0.287 0.000
S81 Open wound of lower leg
0.712 0.288 0.000
S00.8 Superficial injury of other parts of head
0.712 0.288 0.000
M54.2 Cervicalgia
0.712 0.288 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.711 0.289 0.000
K51.9 Ulcerative colitis, unspecified
0.710 0.290 0.000
S01.2 Open wound of nose
0.710 0.290 0.000
G55.8 Nerve root and plexus compressions in other diseases classified elsewhere
0.709 0.291 0.000
O74 Complications of anaesthesia during labour and delivery
0.709 0.291 0.000
O71 Other obstetric trauma
0.709 0.291 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.709 0.291 0.000
O61 Failed induction of labour
0.709 0.291 0.000
O60 Preterm delivery
0.709 0.291 0.000
S32.8 Fracture of other and unspecified parts of lumbar spine and pelvis
0.709 0.291 0.000
M25.8 Other specified joint disorders
0.709 0.291 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.709 0.291 0.000
T47.1 Other antacids and anti-gastric-secretion drugs
0.707 0.293 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.706 0.294 0.000
M22.2 Patellofemoral disorders
0.704 0.296 0.000
Q85 Phakomatoses, not elsewhere classified
0.703 0.297 0.000
M24.16 Other articular cartilage disorders (Lower leg)
0.703 0.297 0.000
S08 Traumatic amputation of part of head
0.702 0.298 0.000
S07 Crushing injury of head
0.702 0.298 0.000
S04 Injury of cranial nerves
0.702 0.298 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.702 0.298 0.000
S00.3 Superficial injury of nose
0.702 0.298 0.000
S80 Superficial injury of lower leg
0.702 0.298 0.000
M49 Spondylopathies in diseases classified elsewhere
0.701 0.298 0.000
T51.0 Ethanol
0.701 0.299 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.701 0.299 0.000
Q50-Q56 Congenital malformations of genital organs
0.700 0.300 0.000
N88 Other noninflammatory disorders of cervix uteri
0.699 0.301 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.699 0.301 0.000
M23.9 Internal derangement of knee, unspecified
0.698 0.302 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.698 0.302 0.000
M23.5 Chronic instability of knee
0.698 0.302 0.000
M23.1 Discoid meniscus (congenital)
0.698 0.302 0.000
M23.0 Cystic meniscus
0.698 0.302 0.000
O30 Multiple gestation
0.696 0.304 0.000
Z36 Antenatal screening
0.696 0.304 0.000
S00.9 Superficial injury of head, part unspecified
0.694 0.306 0.000
M10 Gout
0.693 0.307 0.000
O43 Placental disorders
0.693 0.307 0.000
T46.4 Angiotensin-converting-enzyme inhibitors
0.692 0.308 0.000
G30-G32 Other degenerative diseases of the nervous system
0.691 0.309 0.000
Chapter I Certain infectious and parasitic diseases
0.691 0.309 0.000
K70-K77 Diseases of liver
0.691 0.309 0.000
Z63.0 Problems in relationship with spouse or partner
0.691 0.309 0.000
M23.4 Loose body in knee
0.691 0.309 0.000
Z35.5 Supervision of elderly primigravida
0.691 0.309 0.000
O73 Retained placenta and membranes, without haemorrhage
0.691 0.309 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.690 0.310 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.690 0.310 0.000
T39.4 Antirheumatics, not elsewhere classified
0.690 0.310 0.000
T39.2 Pyrazolone derivatives
0.690 0.310 0.000
G57.8 Other mononeuropathies of lower limb
0.690 0.310 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.688 0.311 0.000
N25-N29 Other disorders of kidney and ureter
0.688 0.311 0.000
G56 Mononeuropathies of upper limb
0.688 0.312 0.000
S32.7 Multiple fractures of lumbar spine and pelvis
0.687 0.313 0.000
K86 Other diseases of pancreas
0.687 0.313 0.000
S01.4 Open wound of cheek and temporomandibular area
0.686 0.314 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.686 0.314 0.000
N18.0 End-stage renal disease
0.686 0.314 0.000
O15 Eclampsia
0.686 0.314 0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria
0.686 0.314 0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension
0.686 0.314 0.000
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium
0.686 0.314 0.000
O11 Pre-existing hypertensive disorder with superimposed proteinuria
0.686 0.314 0.000
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium
0.685 0.315 0.000
M65-M68 Disorders of synovium and tendon
0.684 0.316 0.000
T79-T79 Certain early complications of trauma
0.683 0.317 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.683 0.317 0.000
K35-K38 Diseases of appendix
0.682 0.318 0.000
T91 Sequelae of injuries of neck and trunk
0.682 0.318 0.000
O45 Premature separation of placenta [abruptio placentae]
0.681 0.319 0.000
O44 Placenta praevia
0.681 0.319 0.000
O33 Maternal care for known or suspected disproportion
0.681 0.319 0.000
O31 Complications specific to multiple gestation
0.681 0.319 0.000
O40 Polyhydramnios
0.681 0.319 0.000
M47.8 Other spondylosis
0.681 0.319 0.000
M23.21 Derangement of meniscus due to old tear or injury (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.681 0.319 0.000
K80.8 Other cholelithiasis
0.680 0.320 0.000
O75.2 Pyrexia during labour, not elsewhere classified
0.680 0.320 0.000
S01.1 Open wound of eyelid and periocular area
0.679 0.321 0.000
M47.22 Other spondylosis with radiculopathy (Cervical region)
0.679 0.321 0.000
Q60-Q64 Congenital malformations of the urinary system
0.679 0.321 0.000
O69.2 Labour and delivery complicated by other cord entanglement
0.679 0.321 0.000
G57.9 Mononeuropathy of lower limb, unspecified
0.678 0.322 0.000
G57.5 Tarsal tunnel syndrome
0.678 0.322 0.000
G57.4 Lesion of medial popliteal nerve
0.678 0.322 0.000
G57.3 Lesion of lateral popliteal nerve
0.678 0.322 0.000
G57.2 Lesion of femoral nerve
0.678 0.322 0.000
G57.1 Meralgia paraesthetica
0.678 0.322 0.000
G57.0 Lesion of sciatic nerve
0.678 0.322 0.000
Chapter VII Diseases of the eye and adnexa
0.677 0.323 0.000
S06 Intracranial injury
0.677 0.323 0.000
T92 Sequelae of injuries of upper limb
0.677 0.323 0.000
K82.4 Cholesterolosis of gallbladder
0.676 0.324 0.000
S32.1 Fracture of sacrum
0.675 0.325 0.000
O41 Other disorders of amniotic fluid and membranes
0.675 0.325 0.000
N18.5 Chronic kidney disease, stage 5
0.674 0.326 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.674 0.326 0.000
M19 Other arthrosis
0.674 0.326 0.000
M48.9 Spondylopathy, unspecified
0.674 0.326 0.000
M48.8 Other specified spondylopathies
0.674 0.326 0.000
M48.5 Collapsed vertebra, not elsewhere classified
0.674 0.326 0.000
M48.4 Fatigue fracture of vertebra
0.674 0.326 0.000
M48.3 Traumatic spondylopathy
0.674 0.326 0.000
M48.2 Kissing spine
0.674 0.326 0.000
M48.1 Ankylosing hyperostosis [Forestier]
0.674 0.326 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.673 0.327 0.000
H60-H62 Diseases of external ear
0.671 0.329 0.000
Z65 Problems related to other psychosocial circumstances
0.671 0.329 0.000
Z64 Problems related to certain psychosocial circumstances
0.671 0.329 0.000
Z62 Other problems related to upbringing
0.671 0.329 0.000
Z61 Problems related to negative life events in childhood
0.671 0.329 0.000
Z59 Problems related to housing and economic circumstances
0.671 0.329 0.000
Z58 Problems related to physical environment
0.671 0.329 0.000
Z56 Problems related to employment and unemployment
0.671 0.329 0.000
Z55 Problems related to education and literacy
0.671 0.329 0.000
K80.0 Calculus of gallbladder with acute cholecystitis
0.671 0.329 0.000
T63 Toxic effect of contact with venomous animals
0.670 0.330 0.000
M31 Other necrotising vasculopathies
0.670 0.330 0.000
F31.9 Bipolar affective disorder, unspecified
0.670 0.330 0.000
M46 Other inflammatory spondylopathies
0.669 0.331 0.000
M54.3 Sciatica
0.669 0.331 0.000
S01.7 Multiple open wounds of head
0.669 0.331 0.000
S01.3 Open wound of ear
0.669 0.331 0.000
S32.0 Fracture of lumbar vertebra
0.668 0.332 0.000
N20 Calculus of kidney and ureter
0.668 0.332 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.667 0.333 0.000
Q89 Other congenital malformations, not elsewhere classified
0.666 0.334 0.000
N17.8 Other acute renal failure
0.665 0.335 0.000
N17.2 Acute renal failure with medullary necrosis
0.665 0.335 0.000
N17.1 Acute renal failure with acute cortical necrosis
0.665 0.335 0.000
N17.0 Acute renal failure with tubular necrosis
0.665 0.335 0.000
M23.24 Derangement of meniscus due to old tear or injury (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.665 0.335 0.000
Z60.9 Problem related to social environment, unspecified
0.665 0.335 0.000
Z60.8 Other problems related to social environment
0.665 0.335 0.000
Z60.5 Target of perceived adverse discrimination and persecution
0.665 0.335 0.000
Z60.4 Social exclusion and rejection
0.665 0.335 0.000
Z60.3 Acculturation difficulty
0.665 0.335 0.000
Z60.1 Atypical parenting situation
0.665 0.335 0.000
Z60.0 Problems of adjustment to life-cycle transitions
0.665 0.335 0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.664 0.336 0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis
0.664 0.336 0.000
S37 Injury of urinary and pelvic organs
0.664 0.336 0.000
S36 Injury of intra-abdominal organs
0.664 0.336 0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level
0.664 0.336 0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level
0.664 0.336 0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis
0.664 0.336 0.000
S31 Open wound of abdomen, lower back and pelvis
0.664 0.336 0.000
Z63.4 Disappearance and death of family member
0.663 0.337 0.000
M23.83 Other internal derangements of knee (Medial collateral ligament or Other and unspecified medial meniscus)
0.663 0.337 0.000
M07 Psoriatic and enteropathic arthropathies
0.661 0.339 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.660 0.340 0.000
S32.5 Fracture of pubis
0.658 0.342 0.000
N61 Inflammatory disorders of breast
0.658 0.342 0.000
S27 Injury of other and unspecified intrathoracic organs
0.657 0.343 0.000
T65 Toxic effect of other and unspecified substances
0.656 0.343 0.000
T62 Toxic effect of other noxious substances eaten as food
0.656 0.343 0.000
T61 Toxic effect of noxious substances eaten as seafood
0.656 0.343 0.000
T60 Toxic effect of pesticides
0.656 0.343 0.000
T57 Toxic effect of other inorganic substances
0.656 0.343 0.000
T54 Toxic effect of corrosive substances
0.656 0.343 0.000
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone
0.656 0.343 0.000
T52 Toxic effect of organic solvents
0.656 0.343 0.000
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants
0.656 0.343 0.000
T58 Toxic effect of carbon monoxide
0.656 0.343 0.000
T55 Toxic effect of soaps and detergents
0.656 0.343 0.000
N81 Female genital prolapse
0.656 0.344 0.000
T43.9 Psychotropic drug, unspecified
0.656 0.344 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.656 0.344 0.000
T43.6 Psychostimulants with abuse potential
0.656 0.344 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.656 0.344 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.656 0.344 0.000
M22.1 Recurrent subluxation of patella
0.655 0.345 0.000
M22.9 Disorder of patella, unspecified
0.655 0.345 0.000
M22.3 Other derangements of patella
0.655 0.345 0.000
M22.0 Recurrent dislocation of patella
0.655 0.345 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.655 0.345 0.000
S50 Superficial injury of forearm
0.655 0.345 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.654 0.346 0.000
M48.08 Spinal stenosis (Sacral and sacrococcygeal region)
0.654 0.346 0.000
M48.05 Spinal stenosis (Thoracolumbar region)
0.654 0.346 0.000
M48.04 Spinal stenosis (Thoracic region)
0.654 0.346 0.000
M48.03 Spinal stenosis (Cervicothoracic region)
0.654 0.346 0.000
M48.01 Spinal stenosis (Occipito-atlanto-axial region)
0.654 0.346 0.000
S82 Fracture of lower leg, including ankle
0.654 0.346 0.000
M14 Arthropathies in other diseases classified elsewhere
0.653 0.347 0.000
M12 Other specific arthropathies
0.653 0.347 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.653 0.347 0.000
M08 Juvenile arthritis
0.653 0.347 0.000
Z35.8 Supervision of other high-risk pregnancies
0.653 0.347 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.653 0.347 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.653 0.347 0.000
Q35-Q37 Cleft lip and cleft palate
0.653 0.347 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.653 0.347 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.653 0.347 0.000
Q00-Q07 Congenital malformations of the nervous system
0.653 0.347 0.000
S00.7 Multiple superficial injuries of head
0.652 0.347 0.000
S00.5 Superficial injury of lip and oral cavity
0.652 0.347 0.000
S00.4 Superficial injury of ear
0.652 0.347 0.000
S00.2 Other superficial injuries of eyelid and periocular area
0.652 0.347 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.652 0.348 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.652 0.348 0.000
S67 Crushing injury of wrist and hand
0.652 0.348 0.000
S65 Injury of blood vessels at wrist and hand level
0.651 0.349 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.650 0.350 0.000
M21.2 Flexion deformity
0.650 0.350 0.000
M24.9 Joint derangement, unspecified
0.650 0.350 0.000
M24.8 Other specific joint derangements, not elsewhere classified
0.650 0.350 0.000
M24.7 Protrusio acetabuli
0.650 0.350 0.000
M24.6 Ankylosis of joint
0.650 0.350 0.000
M24.5 Contracture of joint
0.650 0.350 0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified
0.650 0.350 0.000
S89 Other and unspecified injuries of lower leg
0.650 0.350 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.648 0.352 0.000
M54.22 Cervicalgia (Cervical region)
0.648 0.352 0.000
Z39 Postpartum care and examination
0.648 0.352 0.000
O42.2 Premature rupture of membranes, labour delayed by therapy
0.647 0.353 0.000
M05 Seropositive rheumatoid arthritis
0.647 0.353 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.647 0.353 0.000
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)
0.647 0.353 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.646 0.354 0.000
G59.0 Diabetic mononeuropathy
0.646 0.354 0.000
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.645 0.355 0.000
O97 Death from sequelae of direct obstetric causes
0.645 0.355 0.000
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery
0.645 0.355 0.000
O95 Obstetric death of unspecified cause
0.645 0.355 0.000
O94 Sequelae of complication of pregnancy, childbirth and the puerperium
0.645 0.355 0.000
Z38 Liveborn infants according to place of birth
0.645 0.355 0.000
Z32 Pregnancy examination and test
0.645 0.355 0.000
Z31 Procreative management
0.645 0.355 0.000
O36.9 Maternal care for foetal problem, unspecified
0.644 0.356 0.000
O75.9 Complication of labour and delivery, unspecified
0.644 0.356 0.000
O75.5 Delayed delivery after artificial rupture of membranes
0.644 0.356 0.000
O75.4 Other complications of obstetric surgery and procedures
0.644 0.356 0.000
O75.3 Other infection during labour
0.644 0.356 0.000
O75.1 Shock during or following labour and delivery
0.644 0.356 0.000
O75.0 Maternal distress during labour and delivery
0.644 0.356 0.000
T45.0 Antiallergic and antiemetic drugs
0.644 0.356 0.000
M23.20 Derangement of meniscus due to old tear or injury (Multiple sites)
0.643 0.357 0.000
S68 Traumatic amputation of wrist and hand
0.642 0.358 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.641 0.359 0.000
M19.9 Arthrosis, unspecified
0.641 0.359 0.000
S32.4 Fracture of acetabulum
0.641 0.359 0.000
M23.27 Derangement of meniscus due to old tear or injury-Capsular
0.641 0.359 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.640 0.360 0.000
F80-F89 Disorders of psychological development
0.640 0.360 0.000
F70-F79 Mental retardation
0.640 0.360 0.000
M23.30 Other meniscus derangements (Multiple sites)
0.640 0.360 0.000
N18.8 Other chronic renal failure
0.638 0.362 0.000
N18.1 Chronic kidney disease, stage 1
0.638 0.362 0.000
S61 Open wound of wrist and hand
0.638 0.362 0.000
F10.0 Acute intoxication
0.638 0.362 0.000
F10.2 Dependence syndrome
0.637 0.363 0.000
M23.34 Other meniscus derangements (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.637 0.363 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.636 0.364 0.000
T90 Sequelae of injuries of head
0.636 0.364 0.000
M70-M79 Other soft tissue disorders
0.635 0.365 0.000
K82.1 Hydrops of gallbladder
0.634 0.366 0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.634 0.366 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.634 0.366 0.000
O47.1 False labour at or after 37 completed weeks of gestation
0.634 0.366 0.000
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)
0.633 0.367 0.000
M48.09 Spinal stenosis (Site unspecified)
0.633 0.367 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.633 0.367 0.000
M23.81 Other internal derangements of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.633 0.367 0.000
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)
0.633 0.367 0.000
M06.0 Seronegative rheumatoid arthritis
0.633 0.367 0.000
Y86 Sequelae of other accidents
0.633 0.367 0.000
O99.6 Diseases of the digestive system complicating pregnancy, childbirth and the puerperium
0.632 0.368 0.000
G61 Inflammatory polyneuropathy
0.632 0.368 0.000
G60 Hereditary and idiopathic neuropathy
0.632 0.368 0.000
G64 Other disorders of peripheral nervous system
0.632 0.368 0.000
T98 Sequelae of other and unspecified effects of external causes
0.631 0.369 0.000
T95 Sequelae of burns, corrosions and frostbite
0.631 0.369 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.631 0.369 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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