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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs116066300
log Bayes Factor = 16.0918
Chromosome 6   position 22,877,032  (GRCh37) Explore rs116066300 on Ensembl!
Variant rs116066300 is part of Cluster X0222

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Chapter XV Pregnancy, childbirth and the puerperium
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.999 0.001 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.999 0.001 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.998 0.002 0.000
I30-I52 Other forms of heart disease
0.998 0.002 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.997 0.003 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.996 0.004 0.000
Chapter XX External causes of morbidity and mortality
0.995 0.005 0.000
E10-E14 Diabetes mellitus
0.995 0.005 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.994 0.006 0.000
E11 Non-insulin-dependent diabetes mellitus
0.993 0.007 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.988 0.012 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.987 0.013 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.974 0.026 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.971 0.029 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.966 0.034 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.963 0.037 0.000
O36 Maternal care for other known or suspected foetal problems
0.959 0.041 0.000
I44 Atrioventricular and left bundle-branch block
0.956 0.044 0.000
Y83.2 Surgical operation with anastomosis, bypass or graft
0.956 0.044 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.949 0.051 0.000
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified
0.946 0.054 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.942 0.058 0.000
M20-M25 Other joint disorders
0.940 0.060 0.000
Chapter XXI Factors influencing health status and contact with health services
0.940 0.060 0.000
M50-M54 Other dorsopathies
0.934 0.066 0.000
M40-M43 Deforming dorsopathies
0.934 0.066 0.000
I44.2 Atrioventricular block, complete
0.932 0.068 0.000
M20 Acquired deformities of fingers and toes
0.931 0.069 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.930 0.070 0.000
I34 Nonrheumatic mitral valve disorders
0.928 0.072 0.000
O26 Maternal care for other conditions predominantly related to pregnancy
0.926 0.074 0.000
I80 Phlebitis and thrombophlebitis
0.922 0.078 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.921 0.079 0.000
I73 Other peripheral vascular diseases
0.918 0.082 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.916 0.084 0.000
E11.2 With renal complications
0.911 0.089 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.908 0.092 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.907 0.093 0.000
E65-E68 Obesity and other hyperalimentation
0.906 0.094 0.000
O30 Multiple gestation
0.906 0.094 0.000
Chapter XXII Codes for special purposes
0.903 0.097 0.000
Z03 Medical observation and evaluation for suspected diseases and conditions
0.902 0.098 0.000
L85 Other epidermal thickening
0.900 0.100 0.000
M43 Other deforming dorsopathies
0.899 0.101 0.000
M65-M68 Disorders of synovium and tendon
0.898 0.102 0.000
O26.8 Other specified pregnancy-related conditions
0.897 0.103 0.000
Z03.8 Observation for other suspected diseases and conditions
0.896 0.104 0.000
L82 Seborrhoeic keratosis
0.894 0.106 0.000
O36.8 Maternal care for other specified foetal problems
0.894 0.106 0.000
Q21 Congenital malformations of cardiac septa
0.893 0.107 0.000
I73.9 Peripheral vascular disease, unspecified
0.892 0.108 0.000
Z37 Outcome of delivery
0.892 0.108 0.000
Y83.6 Removal of other organ (partial) (total)
0.891 0.109 0.000
D68 Other coagulation defects
0.890 0.110 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.887 0.113 0.000
E11.5 With peripheral circulatory complications
0.884 0.116 0.000
I71 Aortic aneurysm and dissection
0.883 0.117 0.000
I74 Arterial embolism and thrombosis
0.881 0.119 0.000
E11.4 With neurological complications
0.881 0.119 0.000
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities
0.879 0.121 0.000
M51 Other intervertebral disk disorders
0.877 0.123 0.000
E11.9 Without complications
0.877 0.123 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.876 0.124 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.875 0.125 0.000
M20.2 Hallux rigidus
0.874 0.126 0.000
I45 Other conduction disorders
0.873 0.127 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.871 0.129 0.000
I50 Heart failure
0.870 0.130 0.000
S00-S09 Injuries to the head
0.870 0.130 0.000
I26 Pulmonary embolism
0.869 0.130 0.000
O60-O75 Complications of labour and delivery
0.868 0.132 0.000
Q21.1 Atrial septal defect
0.867 0.133 0.000
E20-E35 Disorders of other endocrine glands
0.864 0.136 0.000
Y83.3 Surgical operation with formation of external stoma
0.862 0.138 0.000
M43.1 Spondylolisthesis
0.861 0.139 0.000
D73 Diseases of spleen
0.860 0.140 0.000
Z37.0 Single live birth
0.860 0.140 0.000
I85 Oesophageal varices
0.860 0.140 0.000
Chapter VIII Diseases of the ear and mastoid process
0.858 0.142 0.000
I46 Cardiac arrest
0.858 0.142 0.000
Z36 Antenatal screening
0.851 0.149 0.000
M20.1 Hallux valgus (acquired)
0.846 0.154 0.000
T66-T78 Other and unspecified effects of external causes
0.844 0.156 0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.843 0.157 0.000
M65 Synovitis and tenosynovitis
0.842 0.158 0.000
D73.0 Hyposplenism
0.841 0.159 0.000
O30.0 Twin pregnancy
0.840 0.160 0.000
E66 Obesity
0.839 0.161 0.000
I34.0 Mitral (valve) insufficiency
0.839 0.161 0.000
E11.3 With ophthalmic complications
0.839 0.161 0.000
I70 Atherosclerosis
0.838 0.162 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.836 0.164 0.000
M43.16 Spondylolisthesis (Lumbar region)
0.836 0.164 0.000
E70-E90 Metabolic disorders
0.833 0.167 0.000
I44.0 Atrioventricular block, first degree
0.833 0.167 0.000
I05-I09 Chronic rheumatic heart diseases
0.832 0.168 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.832 0.168 0.000
L85.9 Epidermal thickening, unspecified
0.824 0.176 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.822 0.178 0.000
L98.9 Disorder of skin and subcutaneous tissue, unspecified
0.816 0.184 0.000
I86 Varicose veins of other sites
0.816 0.184 0.000
I50.1 Left ventricular failure
0.813 0.187 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.812 0.188 0.000
M51.2 Other specified intervertebral disk displacement
0.810 0.190 0.000
M20.5 Other deformities of toe(s) (acquired)
0.808 0.192 0.000
O36.6 Maternal care for excessive foetal growth
0.808 0.192 0.000
L98.8 Other specified disorders of skin and subcutaneous tissue
0.805 0.195 0.000
E11.0 With coma
0.805 0.195 0.000
Y84.6 Urinary catheterisation
0.804 0.196 0.000
O23 Infections of genito-urinary tract in pregnancy
0.804 0.196 0.000
L98.0 Pyogenic granuloma
0.803 0.197 0.000
O72 Postpartum haemorrhage
0.803 0.197 0.000
Chapter XI Diseases of the digestive system
0.802 0.198 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.800 0.200 0.000
Z04 Examination and observation for other reasons
0.800 0.200 0.000
L89 Decubitus ulcer
0.800 0.200 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.798 0.202 0.000
I49 Other cardiac arrhythmias
0.797 0.203 0.000
L20-L30 Dermatitis and eczema
0.797 0.203 0.000
L80 Vitiligo
0.796 0.203 0.000
M50 Cervical disk disorders
0.793 0.207 0.000
M23 Internal derangement of knee
0.792 0.208 0.000
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care
0.790 0.210 0.000
E66.9 Obesity, unspecified
0.789 0.211 0.000
I38 Endocarditis, valve unspecified
0.786 0.214 0.000
H65-H75 Diseases of middle ear and mastoid
0.786 0.214 0.000
I85.9 Oesophageal varices without bleeding
0.783 0.217 0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants
0.783 0.217 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.782 0.218 0.000
O20 Haemorrhage in early pregnancy
0.782 0.218 0.000
I72 Other aneurysm
0.781 0.218 0.000
X50-X57 Overexertion, travel and privation
0.781 0.219 0.000
O44 Placenta praevia
0.781 0.219 0.000
O85-O92 Complications predominantly related to the puerperium
0.780 0.220 0.000
E83 Disorders of mineral metabolism
0.780 0.220 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.779 0.221 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.777 0.223 0.000
I77 Other disorders of arteries and arterioles
0.776 0.224 0.000
X60-X84 Intentional self-harm
0.776 0.224 0.000
M65.9 Synovitis and tenosynovitis, unspecified
0.774 0.226 0.000
I33 Acute and subacute endocarditis
0.774 0.226 0.000
K70-K77 Diseases of liver
0.773 0.227 0.000
D69 Purpura and other haemorrhagic conditions
0.772 0.228 0.000
O48 Prolonged pregnancy
0.772 0.228 0.000
D50-D53 Nutritional anaemias
0.772 0.228 0.000
L50-L54 Urticaria and erythema
0.771 0.229 0.000
Q60-Q64 Congenital malformations of the urinary system
0.769 0.231 0.000
E11.1 With ketoacidosis
0.768 0.232 0.000
O36.4 Maternal care for intra-uterine death
0.768 0.232 0.000
D60-D64 Aplastic and other anaemias
0.766 0.234 0.000
I82 Other venous embolism and thrombosis
0.764 0.236 0.000
I34.2 Nonrheumatic mitral (valve) stenosis
0.763 0.237 0.000
Chapter I Certain infectious and parasitic diseases
0.763 0.237 0.000
E14 Unspecified diabetes mellitus
0.762 0.238 0.000
Z03.9 Observation for suspected disease or condition, unspecified
0.761 0.239 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.761 0.239 0.000
L84 Corns and callosities
0.760 0.240 0.000
M15-M19 Arthrosis
0.760 0.240 0.000
M60-M63 Disorders of muscles
0.759 0.241 0.000
I37 Pulmonary valve disorders
0.758 0.241 0.000
M24 Other specific joint derangements
0.757 0.243 0.000
I45.9 Conduction disorder, unspecified
0.755 0.244 0.000
E40-E46 Malnutrition
0.753 0.247 0.000
Y84.2 Radiological procedure and radiotherapy
0.753 0.247 0.000
O36.0 Maternal care for rhesus isoimmunisation
0.752 0.248 0.000
M20.3 Other deformity of hallux (acquired)
0.750 0.250 0.000
M05-M14 Inflammatory polyarthropathies
0.748 0.252 0.000
Z34 Supervision of normal pregnancy
0.748 0.252 0.000
I44.3 Other and unspecified atrioventricular block
0.747 0.253 0.000
Chapter V Mental and behavioural disorders
0.747 0.253 0.000
Z35 Supervision of high-risk pregnancy
0.746 0.253 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.745 0.255 0.000
T78 Adverse effects, not elsewhere classified
0.744 0.256 0.000
D80-D89 Certain disorders involving the immune mechanism
0.744 0.256 0.000
I80.9 Phlebitis and thrombophlebitis of unspecified site
0.743 0.257 0.000
L91 Hypertrophic disorders of skin
0.743 0.257 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.742 0.257 0.000
I08 Multiple valve diseases
0.739 0.261 0.000
X20-X29 Contact with venomous animals and plants
0.739 0.261 0.000
V20-V29 Motorcycle rider injured in transport accident
0.739 0.261 0.000
Q50-Q56 Congenital malformations of genital organs
0.738 0.262 0.000
O80-O84 Delivery
0.737 0.263 0.000
D68.0 Von Willebrand's disease
0.737 0.263 0.000
I36 Nonrheumatic tricuspid valve disorders
0.736 0.264 0.000
L40-L45 Papulosquamous disorders
0.734 0.266 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.734 0.266 0.000
I46.0 Cardiac arrest with successful resuscitation
0.732 0.268 0.000
S90-S99 Injuries to the ankle and foot
0.731 0.269 0.000
M43.0 Spondylolysis
0.730 0.270 0.000
O24 Diabetes mellitus in pregnancy
0.730 0.270 0.000
L81 Other disorders of pigmentation
0.730 0.270 0.000
M70-M79 Other soft tissue disorders
0.730 0.270 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.729 0.271 0.000
Z37.2 Twins, both liveborn
0.729 0.271 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.728 0.272 0.000
Y60.0 During surgical operation
0.728 0.272 0.000
Z04.3 Examination and observation following other accident
0.728 0.272 0.000
Q28 Other congenital malformations of circulatory system
0.727 0.273 0.000
L92 Granulomatous disorders of skin and subcutaneous tissue
0.726 0.274 0.000
M53 Other dorsopathies, not elsewhere classified
0.725 0.275 0.000
O43 Placental disorders
0.722 0.278 0.000
Y84.8 Other medical procedures
0.721 0.279 0.000
E34 Other endocrine disorders
0.720 0.280 0.000
O32.1 Maternal care for breech presentation
0.720 0.280 0.000
Y43 Primarily systemic agents
0.719 0.281 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.718 0.282 0.000
I70.2 Atherosclerosis of arteries of the extremities
0.718 0.282 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.716 0.284 0.000
L10-L14 Bullous disorders
0.716 0.284 0.000
I52 Other heart disorders in diseases classified elsewhere
0.716 0.284 0.000
I48 Atrial fibrillation and flutter
0.716 0.284 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.716 0.284 0.000
I41 Myocarditis in diseases classified elsewhere
0.716 0.284 0.000
I40 Acute myocarditis
0.716 0.284 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.716 0.284 0.000
I32 Pericarditis in diseases classified elsewhere
0.716 0.284 0.000
I30 Acute pericarditis
0.716 0.284 0.000
I45.6 Preexcitation syndrome
0.715 0.285 0.000
Z36.9 Antenatal screening, unspecified
0.715 0.285 0.000
S00 Superficial injury of head
0.715 0.285 0.000
D68.6 Other Thrombophilia
0.715 0.285 0.000
O45 Premature separation of placenta [abruptio placentae]
0.715 0.285 0.000
O41 Other disorders of amniotic fluid and membranes
0.715 0.285 0.000
O33 Maternal care for known or suspected disproportion
0.715 0.285 0.000
O31 Complications specific to multiple gestation
0.715 0.285 0.000
O40 Polyhydramnios
0.715 0.285 0.000
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.714 0.286 0.000
L95 Vasculitis limited to skin, not elsewhere classified
0.714 0.286 0.000
L94 Other localised connective tissue disorders
0.714 0.286 0.000
L93 Lupus erythematosus
0.714 0.286 0.000
L87 Transepidermal elimination disorders
0.714 0.286 0.000
L88 Pyoderma gangrenosum
0.714 0.286 0.000
L86 Keratoderma in diseases classified elsewhere
0.714 0.286 0.000
L83 Acanthosis nigricans
0.714 0.286 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.714 0.286 0.000
Y35-Y36 Legal intervention and operations of war
0.714 0.286 0.000
Y10-Y34 Event of undetermined intent
0.714 0.286 0.000
Y00-Y09 Assault
0.714 0.286 0.000
X85-X99 Assault
0.714 0.286 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.714 0.286 0.000
X30-X39 Exposure to forces of nature
0.714 0.286 0.000
X10-X19 Contact with heat and hot substances
0.714 0.286 0.000
X00-X09 Exposure to smoke, fire and flames
0.714 0.286 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.714 0.286 0.000
W75-W84 Other accidental threats to breathing
0.714 0.286 0.000
W65-W74 Accidental drowning and submersion
0.714 0.286 0.000
W50-W64 Exposure to animate mechanical forces
0.714 0.286 0.000
V98-V99 Other and unspecified transport accidents
0.714 0.286 0.000
V95-V97 Air and space transport accidents
0.714 0.286 0.000
V90-V94 Water transport accidents
0.714 0.286 0.000
V80-V89 Other land transport accidents
0.714 0.286 0.000
V70-V79 Bus occupant injured in transport accident
0.714 0.286 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.714 0.286 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.714 0.286 0.000
V40-V49 Car occupant injured in transport accident
0.714 0.286 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.714 0.286 0.000
V01-V09 Pedestrian injured in transport accident
0.714 0.286 0.000
M20.6 Acquired deformity of toe(s), unspecified
0.714 0.286 0.000
E13 Other specified diabetes mellitus
0.713 0.286 0.000
E12 Malnutrition-related diabetes mellitus
0.713 0.286 0.000
O35.1 Maternal care for (suspected) chromosomal abnormality in foetus
0.713 0.287 0.000
Z32 Pregnancy examination and test
0.713 0.287 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.713 0.287 0.000
M91-M94 Chondropathies
0.712 0.288 0.000
E11.8 With unspecified complications
0.712 0.288 0.000
E11.7 With multiple complications
0.712 0.288 0.000
E11.6 With other specified complications
0.712 0.288 0.000
O72.1 Other immediate postpartum haemorrhage
0.712 0.288 0.000
Y84.1 Kidney dialysis
0.709 0.291 0.000
K70 Alcoholic liver disease
0.709 0.291 0.000
D55-D59 Haemolytic anaemias
0.708 0.292 0.000
S09 Other and unspecified injuries of head
0.708 0.292 0.000
M86-M90 Other osteopathies
0.705 0.295 0.000
S05 Injury of eye and orbit
0.705 0.295 0.000
O32.5 Maternal care for multiple gestation with malpresentation of one foetus or more
0.704 0.296 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.704 0.296 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.703 0.296 0.000
I71.0 Dissection of aorta [any part]
0.703 0.297 0.000
M65.3 Trigger finger
0.703 0.297 0.000
M20.0 Deformity of finger(s)
0.703 0.297 0.000
O00-O08 Pregnancy with abortive outcome
0.702 0.298 0.000
O21 Excessive vomiting in pregnancy
0.701 0.299 0.000
I87 Other disorders of veins
0.699 0.301 0.000
O29 Complications of anaesthesia during pregnancy
0.698 0.301 0.000
O28 Abnormal findings on antenatal screening of mother
0.698 0.301 0.000
O22 Venous complications in pregnancy
0.698 0.301 0.000
O25 Malnutrition in pregnancy
0.698 0.301 0.000
D68.9 Coagulation defect, unspecified
0.698 0.302 0.000
I51 Complications and ill-defined descriptions of heart disease
0.698 0.302 0.000
D69.6 Thrombocytopenia, unspecified
0.698 0.302 0.000
D68.8 Other specified coagulation defects
0.697 0.303 0.000
T93 Sequelae of injuries of lower limb
0.697 0.303 0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis
0.697 0.303 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.696 0.304 0.000
Q80-Q89 Other congenital malformations
0.696 0.304 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.696 0.304 0.000
Q35-Q37 Cleft lip and cleft palate
0.696 0.304 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.696 0.304 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.696 0.304 0.000
Q00-Q07 Congenital malformations of the nervous system
0.696 0.304 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.695 0.305 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.693 0.307 0.000
I88 Nonspecific lymphadenitis
0.693 0.307 0.000
I81 Portal vein thrombosis
0.693 0.307 0.000
M51.0 Lumbar and other intervertebral disk disorders with myelopathy
0.692 0.308 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.691 0.309 0.000
Z36.8 Other antenatal screening
0.691 0.309 0.000
Y83.5 Amputation of limb(s)
0.690 0.310 0.000
Y83.0 Surgical operation with transplant of whole organ
0.690 0.310 0.000
M80-M85 Disorders of bone density and structure
0.689 0.310 0.000
O72.0 Third-stage haemorrhage
0.689 0.311 0.000
M18 Arthrosis of first carpometacarpal joint
0.689 0.311 0.000
I34.1 Mitral (valve) prolapse
0.689 0.311 0.000
L60-L75 Disorders of skin appendages
0.688 0.312 0.000
O36.7 Maternal care for viable foetus in abdominal pregnancy
0.688 0.312 0.000
O36.3 Maternal care for signs of foetal hypoxia
0.688 0.312 0.000
O36.2 Maternal care for hydrops foetalis
0.688 0.312 0.000
O36.1 Maternal care for other isoimmunisation
0.688 0.312 0.000
I50.0 Congestive heart failure
0.687 0.313 0.000
D51 Vitamin B12 deficiency anaemia
0.687 0.313 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.686 0.314 0.000
I44.6 Other and unspecified fascicular block
0.685 0.314 0.000
I44.5 Left posterior fascicular block
0.685 0.314 0.000
I44.4 Left anterior fascicular block
0.685 0.314 0.000
H65 Nonsuppurative otitis media
0.685 0.315 0.000
L29 Pruritus
0.685 0.315 0.000
E83.1 Disorders of iron metabolism
0.685 0.315 0.000
E83.5 Disorders of calcium metabolism
0.684 0.316 0.000
I49.0 Ventricular fibrillation and flutter
0.684 0.316 0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.683 0.316 0.000
K65-K67 Diseases of peritoneum
0.683 0.317 0.000
O23.4 Unspecified infection of urinary tract in pregnancy
0.682 0.318 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.682 0.318 0.000
Z03.1 Observation for suspected malignant neoplasm
0.681 0.318 0.000
M65.91 Synovitis and tenosynovitis, unspecified (Shoulder region)
0.681 0.319 0.000
Z36.2 Other antenatal screening based on amniocentesis
0.681 0.319 0.000
S60-S69 Injuries to the wrist and hand
0.681 0.319 0.000
E23 Hypofunction and other disorders of pituitary gland
0.680 0.320 0.000
T33-T35 Frostbite
0.680 0.320 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.680 0.320 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.680 0.320 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.680 0.320 0.000
T00-T07 Injuries involving multiple body regions
0.680 0.320 0.000
S10-S19 Injuries to the neck
0.680 0.320 0.000
I77.1 Stricture of artery
0.679 0.321 0.000
E27 Other disorders of adrenal gland
0.679 0.321 0.000
I78 Diseases of capillaries
0.679 0.321 0.000
I10-I15 Hypertensive diseases
0.679 0.321 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.678 0.322 0.000
L98.7 Excessive and redundant skin and subcutaneous tissue
0.678 0.322 0.000
L98.6 Other infiltrative disorders of skin and subcutaneous tissue
0.678 0.322 0.000
L98.5 Mucinosis of skin
0.678 0.322 0.000
L98.4 Chronic ulcer of skin, not elsewhere classified
0.678 0.322 0.000
L98.3 Eosinophilic cellulitis [Wells]
0.678 0.322 0.000
L98.2 Febrile neutrophilic dermatosis [Sweet]
0.678 0.322 0.000
L98.1 Factitial dermatitis
0.678 0.322 0.000
I80.8 Phlebitis and thrombophlebitis of other sites
0.678 0.322 0.000
U88 Agent resistant to multiple antibiotics
0.678 0.322 0.000
S06 Intracranial injury
0.677 0.323 0.000
D67 Hereditary factor IX deficiency
0.675 0.325 0.000
D66 Hereditary factor VIII deficiency
0.675 0.325 0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.675 0.325 0.000
M51.8 Other specified intervertebral disk disorders
0.675 0.325 0.000
O47 False labour
0.675 0.325 0.000
Z03.5 Observation for other suspected cardiovascular diseases
0.675 0.325 0.000
T79-T79 Certain early complications of trauma
0.675 0.325 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.674 0.326 0.000
M34 Systemic sclerosis
0.674 0.326 0.000
M33 Dermatopolymyositis
0.674 0.326 0.000
M32 Systemic lupus erythematosus
0.674 0.326 0.000
M30 Polyarteritis nodosa and related conditions
0.674 0.326 0.000
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities
0.673 0.327 0.000
L85.8 Other specified epidermal thickening
0.673 0.327 0.000
I49.3 Ventricular premature depolarisation
0.672 0.328 0.000
Z03.6 Observation for suspected toxic effect from ingested substance
0.672 0.328 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.672 0.328 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.671 0.329 0.000
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified
0.671 0.329 0.000
O32.8 Maternal care for other malpresentation of foetus
0.671 0.329 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.670 0.330 0.000
M42 Spinal osteochondrosis
0.670 0.330 0.000
M40 Kyphosis and lordosis
0.670 0.330 0.000
M50.1 Cervical disk disorder with radiculopathy
0.670 0.330 0.000
I08.0 Disorders of both mitral and aortic valves
0.670 0.330 0.000
W20-W49 Exposure to inanimate mechanical forces
0.669 0.330 0.000
S40-S49 Injuries to the shoulder and upper arm
0.669 0.331 0.000
E50-E64 Other nutritional deficiencies
0.668 0.332 0.000
Q27 Other congenital malformations of peripheral vascular system
0.666 0.333 0.000
Q26 Congenital malformations of great veins
0.666 0.333 0.000
Q25 Congenital malformations of great arteries
0.666 0.333 0.000
Q24 Other congenital malformations of heart
0.666 0.333 0.000
Q22 Congenital malformations of pulmonary and tricuspid valves
0.666 0.333 0.000
Q20 Congenital malformations of cardiac chambers and connexions
0.666 0.333 0.000
L89.2 Stage III decubitus ulcer
0.666 0.334 0.000
O63 Long labour
0.665 0.335 0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.665 0.335 0.000
I34.8 Other nonrheumatic mitral valve disorders
0.665 0.335 0.000
D64 Other anaemias
0.665 0.335 0.000
T68 Hypothermia
0.665 0.335 0.000
M65.94 Synovitis and tenosynovitis, unspecified (Hand)
0.665 0.335 0.000
I46.9 Cardiac arrest, unspecified
0.664 0.336 0.000
O26.7 Subluxation of symphysis (pubis) in pregnancy, childbirth and the puerperium
0.664 0.336 0.000
O26.6 Liver disorders in pregnancy, childbirth and the puerperium
0.664 0.336 0.000
O26.5 Maternal hypotension syndrome
0.664 0.336 0.000
O26.4 Herpes gestationis
0.664 0.336 0.000
O26.3 Retained intra-uterine contraceptive device in pregnancy
0.664 0.336 0.000
O26.2 Pregnancy care of habitual aborter
0.664 0.336 0.000
O26.1 Low weight gain in pregnancy
0.664 0.336 0.000
O26.0 Excessive weight gain in pregnancy
0.664 0.336 0.000
M65.93 Synovitis and tenosynovitis, unspecified (Forearm)
0.662 0.337 0.000
Z36.3 Antenatal screening for malformations using ultrasound and other physical methods
0.662 0.338 0.000
T90 Sequelae of injuries of head
0.661 0.338 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.661 0.339 0.000
Z38 Liveborn infants according to place of birth
0.660 0.340 0.000
Z31 Procreative management
0.660 0.340 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.660 0.340 0.000
Y52 Agents primarily affecting the cardiovascular system
0.659 0.341 0.000
O36.5 Maternal care for poor foetal growth
0.659 0.341 0.000
I86.4 Gastric varices
0.659 0.341 0.000
H60-H62 Diseases of external ear
0.658 0.342 0.000
I73.8 Other specified peripheral vascular diseases
0.658 0.342 0.000
I73.1 Thromboangiitis obliterans [Buerger]
0.658 0.342 0.000
Y84.9 Medical procedure, unspecified
0.657 0.343 0.000
Y84.7 Blood-sampling
0.657 0.343 0.000
Y84.5 Insertion of gastric or duodenal sound
0.657 0.343 0.000
Y84.4 Aspiration of fluid
0.657 0.343 0.000
Y84.3 Shock therapy
0.657 0.343 0.000
I86.1 Scrotal varices
0.657 0.343 0.000
Q23 Congenital malformations of aortic and mitral valves
0.655 0.344 0.000
O46.9 Antepartum haemorrhage, unspecified
0.655 0.345 0.000
M50.3 Other cervical disk degeneration
0.653 0.347 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.651 0.349 0.000
I42 Cardiomyopathy
0.651 0.349 0.000
Z10 Routine general health check-up of defined subpopulation
0.651 0.349 0.000
I31 Other diseases of pericardium
0.651 0.349 0.000
O61 Failed induction of labour
0.650 0.350 0.000
I28 Other diseases of pulmonary vessels
0.650 0.350 0.000
Z34.8 Supervision of other normal pregnancy
0.650 0.350 0.000
E67 Other hyperalimentation
0.650 0.350 0.000
E68 Sequelae of hyperalimentation
0.650 0.350 0.000
E65 Localised adiposity
0.650 0.350 0.000
O30.9 Multiple gestation, unspecified
0.649 0.351 0.000
O30.8 Other multiple gestation
0.649 0.351 0.000
O30.2 Quadruplet pregnancy
0.649 0.351 0.000
O30.1 Triplet pregnancy
0.649 0.351 0.000
Chapter VI Diseases of the nervous system
0.649 0.351 0.000
Z03.2 Observation for suspected mental and behavioural disorders
0.647 0.353 0.000
Z03.0 Observation for suspected tuberculosis
0.647 0.353 0.000
Z35.2 Supervision of pregnancy with other poor reproductive or obstetric history
0.646 0.354 0.000
L85.3 Xerosis cutis
0.645 0.354 0.000
L85.2 Keratosis punctata (palmaris et plantaris)
0.645 0.354 0.000
L85.1 Acquired keratosis [keratoderma] palmaris et plantaris
0.645 0.354 0.000
L85.0 Acquired ichthyosis
0.645 0.354 0.000
Z09 Follow-up examination after treatment for conditions other than malignant neoplasms
0.645 0.355 0.000
M43.9 Deforming dorsopathy, unspecified
0.645 0.355 0.000
M43.8 Other specified deforming dorsopathies
0.645 0.355 0.000
M43.6 Torticollis
0.645 0.355 0.000
M43.5 Other recurrent vertebral subluxation
0.645 0.355 0.000
M43.4 Other recurrent atlantoaxial subluxation
0.645 0.355 0.000
M43.3 Recurrent atlantoaxial subluxation with myelopathy
0.645 0.355 0.000
M43.2 Other fusion of spine
0.645 0.355 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.644 0.356 0.000
M66 Spontaneous rupture of synovium and tendon
0.644 0.356 0.000
U80 Agent resistant to penicillin and related antibiotics
0.644 0.356 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.643 0.357 0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria
0.642 0.358 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.641 0.358 0.000
Q21.9 Congenital malformation of cardiac septum, unspecified
0.640 0.359 0.000
Q21.8 Other congenital malformations of cardiac septa
0.640 0.359 0.000
Q21.4 Aortopulmonary septal defect
0.640 0.359 0.000
Q21.3 Tetralogy of Fallot
0.640 0.359 0.000
Q21.2 Atrioventricular septal defect
0.640 0.359 0.000
Q21.0 Ventricular septal defect
0.640 0.359 0.000
E88 Other metabolic disorders
0.640 0.360 0.000
Z37.9 Outcome of delivery unspecified
0.639 0.361 0.000
Z37.7 Other multiple births, all stillborn
0.639 0.361 0.000
Z37.6 Other multiple births, some liveborn
0.639 0.361 0.000
Z37.5 Other multiple births, all liveborn
0.639 0.361 0.000
Z37.4 Twins, both stillborn
0.639 0.361 0.000
Z37.3 Twins, one liveborn and one stillborn
0.639 0.361 0.000
Z37.1 Single stillbirth
0.639 0.361 0.000
F10.1 Harmful use
0.639 0.361 0.000
D68.5 Primary Thrombophilia
0.638 0.362 0.000
D68.4 Acquired coagulation factor deficiency
0.638 0.362 0.000
D68.1 Hereditary factor XI deficiency
0.638 0.362 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.636 0.364 0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.636 0.364 0.000
D74 Methaemoglobinaemia
0.636 0.364 0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.636 0.364 0.000
D71 Functional disorders of polymorphonuclear neutrophils
0.636 0.364 0.000
S50-S59 Injuries to the elbow and forearm
0.635 0.365 0.000
Y40 Systemic antibiotics
0.635 0.365 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.635 0.365 0.000
O20.9 Haemorrhage in early pregnancy, unspecified
0.634 0.366 0.000
L29.0 Pruritus ani
0.633 0.367 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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