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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs116078501
log Bayes Factor = 9.50922
Chromosome 2   position 8,698,802  (GRCh37) Explore rs116078501 on Ensembl!
Variant rs116078501 is part of Cluster X0078

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XI Diseases of the digestive system
1.000 0.000 0.000
Chapter II Neoplasms
0.999 0.001 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.999 0.001 0.000
Chapter XX External causes of morbidity and mortality
0.999 0.001 0.000
K55-K64 Other diseases of intestines
0.998 0.002 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.997 0.003 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.996 0.004 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.995 0.005 0.000
K58 Irritable bowel syndrome
0.993 0.007 0.000
Chapter IX Diseases of the circulatory system
0.992 0.008 0.000
I73 Other peripheral vascular diseases
0.990 0.010 0.000
Chapter X Diseases of the respiratory system
0.990 0.010 0.000
D45 Polycythaemia vera
0.990 0.010 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.989 0.011 0.000
K50-K52 Noninfective enteritis and colitis
0.989 0.011 0.000
I73.9 Peripheral vascular disease, unspecified
0.988 0.012 0.000
K51 Ulcerative colitis
0.987 0.013 0.000
K58.9 Irritable bowel syndrome without diarrhoea
0.987 0.013 0.000
K51.9 Ulcerative colitis, unspecified
0.986 0.014 0.000
L60-L75 Disorders of skin appendages
0.982 0.018 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.977 0.023 0.000
K60 Fissure and fistula of anal and rectal regions
0.977 0.023 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.975 0.025 0.000
L72 Follicular cysts of skin and subcutaneous tissue
0.975 0.025 0.000
I71 Aortic aneurysm and dissection
0.974 0.026 0.000
L08 Other local infections of skin and subcutaneous tissue
0.970 0.030 0.000
J40-J47 Chronic lower respiratory diseases
0.968 0.032 0.000
C15-C26 Malignant neoplasms of digestive organs
0.966 0.034 0.000
Y83.6 Removal of other organ (partial) (total)
0.963 0.037 0.000
L72.1 Trichilemmal cyst
0.963 0.037 0.000
L08.9 Local infection of skin and subcutaneous tissue, unspecified
0.961 0.039 0.000
J43 Emphysema
0.956 0.044 0.000
K60.1 Chronic anal fissure
0.956 0.044 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.954 0.046 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.949 0.051 0.000
J43.9 Emphysema, unspecified
0.948 0.052 0.000
C15 Malignant neoplasm of oesophagus
0.947 0.053 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.943 0.057 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.939 0.061 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.938 0.062 0.000
Y83.5 Amputation of limb(s)
0.937 0.063 0.000
L72.0 Epidermal cyst
0.937 0.063 0.000
K70-K77 Diseases of liver
0.932 0.068 0.000
J09-J18 Influenza and pneumonia
0.931 0.069 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.928 0.072 0.000
K70 Alcoholic liver disease
0.905 0.095 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.904 0.096 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.903 0.097 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.898 0.102 0.000
Y40 Systemic antibiotics
0.897 0.103 0.000
D41.4 Bladder
0.896 0.104 0.000
K56 Paralytic ileus and intestinal obstruction without hernia
0.893 0.107 0.000
K57 Diverticular disease of intestine
0.890 0.110 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.890 0.110 0.000
Y83.2 Surgical operation with anastomosis, bypass or graft
0.890 0.110 0.000
I72 Other aneurysm
0.889 0.111 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.884 0.116 0.000
I60-I69 Cerebrovascular diseases
0.880 0.120 0.000
C21 Malignant neoplasm of anus and anal canal
0.878 0.122 0.000
D55-D59 Haemolytic anaemias
0.878 0.122 0.000
K51.8 Other ulcerative colitis
0.876 0.124 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.875 0.125 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.872 0.128 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.872 0.128 0.000
L82 Seborrhoeic keratosis
0.871 0.129 0.000
K07 Dentofacial anomalies [including malocclusion]
0.869 0.131 0.000
I74 Arterial embolism and thrombosis
0.867 0.133 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.865 0.135 0.000
W00-W19 Falls
0.863 0.137 0.000
Y83.4 Other reconstructive surgery
0.862 0.138 0.000
K04 Diseases of pulp and periapical tissues
0.860 0.140 0.000
C15.5 Lower third of oesophagus
0.860 0.140 0.000
J18 Pneumonia, organism unspecified
0.860 0.140 0.000
I60 Subarachnoid haemorrhage
0.858 0.142 0.000
C15.9 Oesophagus, unspecified
0.857 0.143 0.000
J42 Unspecified chronic bronchitis
0.852 0.148 0.000
K08 Other disorders of teeth and supporting structures
0.852 0.148 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.851 0.149 0.000
K58.0 Irritable bowel syndrome with diarrhoea
0.851 0.149 0.000
I70 Atherosclerosis
0.850 0.150 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.844 0.156 0.000
D37.4 Colon
0.843 0.157 0.000
K51.5 Mucosal proctocolitis
0.841 0.159 0.000
J45 Asthma
0.835 0.165 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.833 0.167 0.000
K70.3 Alcoholic cirrhosis of liver
0.831 0.169 0.000
K56.4 Other impaction of intestine
0.829 0.171 0.000
J18.9 Pneumonia, unspecified
0.827 0.173 0.000
J20-J22 Other acute lower respiratory infections
0.827 0.173 0.000
Chapter I Certain infectious and parasitic diseases
0.827 0.173 0.000
K11 Diseases of salivary glands
0.826 0.173 0.000
I60.9 Subarachnoid haemorrhage, unspecified
0.825 0.175 0.000
C15.4 Middle third of oesophagus
0.824 0.176 0.000
D59 Acquired haemolytic anaemia
0.823 0.177 0.000
K10 Other diseases of jaws
0.818 0.182 0.000
Y40.9 Systemic antibiotic, unspecified
0.818 0.182 0.000
C71 Malignant neoplasm of brain
0.817 0.183 0.000
D75 Other diseases of blood and blood-forming organs
0.816 0.184 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.812 0.188 0.000
J90-J94 Other diseases of pleura
0.809 0.191 0.000
L08.8 Other specified local infections of skin and subcutaneous tissue
0.808 0.192 0.000
K57.1 Diverticular disease of small intestine without perforation or abscess
0.803 0.197 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.802 0.198 0.000
D37.3 Appendix
0.801 0.199 0.000
K08.3 Retained dental root
0.801 0.199 0.000
C25 Malignant neoplasm of pancreas
0.800 0.200 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.799 0.201 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.798 0.202 0.000
K11.2 Sialoadenitis
0.796 0.204 0.000
K60.2 Anal fissure, unspecified
0.796 0.204 0.000
Chapter VI Diseases of the nervous system
0.794 0.206 0.000
C64-C68 Malignant neoplasms of urinary tract
0.787 0.213 0.000
Y45.1 Salicylates
0.786 0.214 0.000
L03 Cellulitis
0.786 0.214 0.000
V20-V29 Motorcycle rider injured in transport accident
0.785 0.215 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.784 0.215 0.000
J11 Influenza, virus not identified
0.784 0.216 0.000
K09 Cysts of oral region, not elsewhere classified
0.783 0.217 0.000
Y83.9 Surgical procedure, unspecified
0.782 0.218 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.782 0.218 0.000
K51.4 Pseudopolyposis of colon
0.782 0.218 0.000
K70.1 Alcoholic hepatitis
0.779 0.221 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.779 0.221 0.000
K02 Dental caries
0.777 0.223 0.000
L73 Other follicular disorders
0.776 0.224 0.000
D37.1 Stomach
0.772 0.228 0.000
C21.0 Anus, unspecified
0.771 0.229 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.770 0.230 0.000
K57.3 Diverticular disease of large intestine without perforation or abscess
0.768 0.232 0.000
Y40.8 Other systemic antibiotics
0.766 0.234 0.000
Y84.9 Medical procedure, unspecified
0.766 0.234 0.000
Y00-Y09 Assault
0.765 0.235 0.000
D72 Other disorders of white blood cells
0.765 0.235 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.764 0.236 0.000
D59.1 Other autoimmune haemolytic anaemias
0.763 0.237 0.000
K14 Diseases of tongue
0.762 0.238 0.000
X20-X29 Contact with venomous animals and plants
0.761 0.239 0.000
Y84.1 Kidney dialysis
0.759 0.241 0.000
J93 Pneumothorax
0.758 0.242 0.000
Y65 Other misadventures during surgical and medical care
0.757 0.243 0.000
V10-V19 Pedal cyclist injured in transport accident
0.756 0.244 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.755 0.245 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.752 0.248 0.000
I70.2 Atherosclerosis of arteries of the extremities
0.751 0.249 0.000
J10 Influenza due to identified influenza virus
0.750 0.250 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.750 0.250 0.000
D75.1 Secondary polycythaemia
0.750 0.250 0.000
J45.9 Asthma, unspecified
0.749 0.251 0.000
I78 Diseases of capillaries
0.747 0.253 0.000
C51-C58 Malignant neoplasms of female genital organs
0.747 0.253 0.000
Y43 Primarily systemic agents
0.746 0.254 0.000
J00-J06 Acute upper respiratory infections
0.745 0.255 0.000
K60.0 Acute anal fissure
0.745 0.255 0.000
K04.4 Acute apical periodontitis of pulpal origin
0.744 0.256 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.744 0.256 0.000
Y83.0 Surgical operation with transplant of whole organ
0.743 0.257 0.000
K10.2 Inflammatory conditions of jaws
0.741 0.259 0.000
I72.8 Aneurysm of other specified arteries
0.741 0.259 0.000
I73.8 Other specified peripheral vascular diseases
0.741 0.259 0.000
I71.0 Dissection of aorta [any part]
0.740 0.259 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.739 0.261 0.000
C88 Malignant immunoproliferative diseases
0.738 0.261 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.738 0.262 0.000
K07.3 Anomalies of tooth position
0.737 0.263 0.000
Q43 Other congenital malformations of intestine
0.735 0.265 0.000
C21.1 Anal canal
0.734 0.266 0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.734 0.266 0.000
I62 Other nontraumatic intracranial haemorrhage
0.734 0.266 0.000
K70.9 Alcoholic liver disease, unspecified
0.733 0.267 0.000
I71.3 Abdominal aortic aneurysm, ruptured
0.730 0.270 0.000
C85.7 Other specified types of non-Hodgkin's lymphoma
0.730 0.270 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.730 0.270 0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.730 0.270 0.000
K63 Other diseases of intestine
0.730 0.270 0.000
C85.1 B-cell lymphoma, unspecified
0.729 0.271 0.000
W18 Other fall on same level
0.729 0.271 0.000
K83 Other diseases of biliary tract
0.727 0.273 0.000
Y44 Agents primarily affecting blood constituents
0.727 0.273 0.000
K04.6 Periapical abscess with sinus
0.727 0.273 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.727 0.273 0.000
C49 Malignant neoplasm of other connective and soft tissue
0.724 0.276 0.000
W13 Fall from, out of or through building or structure
0.723 0.277 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.721 0.279 0.000
J46 Status asthmaticus
0.721 0.279 0.000
M40-M43 Deforming dorsopathies
0.720 0.280 0.000
T79-T79 Certain early complications of trauma
0.719 0.281 0.000
Y84.4 Aspiration of fluid
0.718 0.282 0.000
K56.2 Volvulus
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.716 0.284 0.000
Y35-Y36 Legal intervention and operations of war
0.716 0.284 0.000
Y10-Y34 Event of undetermined intent
0.716 0.284 0.000
X85-X99 Assault
0.716 0.284 0.000
X30-X39 Exposure to forces of nature
0.716 0.284 0.000
X10-X19 Contact with heat and hot substances
0.716 0.284 0.000
X00-X09 Exposure to smoke, fire and flames
0.716 0.284 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.716 0.284 0.000
W75-W84 Other accidental threats to breathing
0.716 0.284 0.000
W65-W74 Accidental drowning and submersion
0.716 0.284 0.000
V98-V99 Other and unspecified transport accidents
0.716 0.284 0.000
V95-V97 Air and space transport accidents
0.716 0.284 0.000
V90-V94 Water transport accidents
0.716 0.284 0.000
V70-V79 Bus occupant injured in transport accident
0.716 0.284 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.716 0.284 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.716 0.284 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.716 0.284 0.000
V01-V09 Pedestrian injured in transport accident
0.716 0.284 0.000
L70 Acne
0.716 0.284 0.000
K64 Haemorrhoids and perianal venous thrombosis
0.716 0.284 0.000
L10-L14 Bullous disorders
0.715 0.285 0.000
C23 Malignant neoplasm of gallbladder
0.714 0.286 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.712 0.288 0.000
J17 Pneumonia in diseases classified elsewhere
0.712 0.288 0.000
I60.2 Subarachnoid haemorrhage from anterior communicating artery
0.711 0.289 0.000
I00-I02 Acute rheumatic fever
0.711 0.289 0.000
K60.4 Rectal fistula
0.711 0.289 0.000
L93 Lupus erythematosus
0.710 0.290 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.710 0.290 0.000
I73.1 Thromboangiitis obliterans [Buerger]
0.710 0.290 0.000
K07.1 Anomalies of jaw-cranial base relationship
0.710 0.290 0.000
C95 Leukaemia of unspecified cell type
0.709 0.290 0.000
C71.9 Brain, unspecified
0.709 0.291 0.000
J92 Pleural plaque
0.709 0.291 0.000
C91 Lymphoid leukaemia
0.708 0.292 0.000
I72.3 Aneurysm of iliac artery
0.708 0.292 0.000
K51.1 Ulcerative (chronic) ileocolitis
0.708 0.292 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.708 0.292 0.000
K01 Embedded and impacted teeth
0.707 0.293 0.000
J22 Unspecified acute lower respiratory infection
0.706 0.294 0.000
D37.0 Lip, oral cavity and pharynx
0.706 0.294 0.000
I72.9 Aneurysm of unspecified site
0.705 0.295 0.000
Q38 Other congenital malformations of tongue, mouth and pharynx
0.704 0.296 0.000
L75 Apocrine sweat disorders
0.704 0.296 0.000
L74 Eccrine sweat disorders
0.704 0.296 0.000
L68 Hypertrichosis
0.704 0.296 0.000
L67 Hair colour and hair shaft abnormalities
0.704 0.296 0.000
L66 Cicatricial alopecia [scarring hair loss]
0.704 0.296 0.000
L65 Other nonscarring hair loss
0.704 0.296 0.000
L64 Androgenic alopecia
0.704 0.296 0.000
L63 Alopecia areata
0.704 0.296 0.000
L62 Nail disorders in diseases classified elsewhere
0.704 0.296 0.000
C71.2 Temporal lobe
0.703 0.297 0.000
K07.4 Malocclusion, unspecified
0.703 0.297 0.000
J93.9 Pneumothorax, unspecified
0.703 0.297 0.000
G70-G73 Diseases of myoneural junction and muscle
0.701 0.299 0.000
L04 Acute lymphadenitis
0.700 0.299 0.000
L01 Impetigo
0.700 0.299 0.000
L00 Staphylococcal scalded skin syndrome
0.700 0.299 0.000
K03 Other diseases of hard tissues of teeth
0.699 0.301 0.000
L72.2 Steatocystoma multiplex
0.699 0.301 0.000
I71.8 Aortic aneurysm of unspecified site, ruptured
0.698 0.302 0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.698 0.302 0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.698 0.302 0.000
I71.1 Thoracic aortic aneurysm, ruptured
0.698 0.302 0.000
Chapter V Mental and behavioural disorders
0.697 0.303 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.697 0.303 0.000
K04.8 Radicular cyst
0.696 0.304 0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver
0.696 0.304 0.000
L08.1 Erythrasma
0.695 0.305 0.000
L08.0 Pyoderma
0.695 0.305 0.000
J41 Simple and mucopurulent chronic bronchitis
0.694 0.306 0.000
J44 Other chronic obstructive pulmonary disease
0.694 0.306 0.000
I67 Other cerebrovascular diseases
0.694 0.306 0.000
D47.1 Chronic myeloproliferative disease
0.693 0.307 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.693 0.307 0.000
C17 Malignant neoplasm of small intestine
0.693 0.307 0.000
D72.8 Other specified disorders of white blood cells
0.692 0.308 0.000
L95 Vasculitis limited to skin, not elsewhere classified
0.691 0.309 0.000
B99-B99 Other infectious diseases
0.691 0.309 0.000
K73 Chronic hepatitis, not elsewhere classified
0.691 0.309 0.000
W01 Fall on same level from slipping, tripping and stumbling
0.690 0.310 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.688 0.312 0.000
D47.4 Osteomyelofibrosis
0.688 0.312 0.000
K56.7 Ileus, unspecified
0.688 0.312 0.000
L03.2 Cellulitis of face
0.688 0.312 0.000
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care
0.687 0.313 0.000
J43.8 Other emphysema
0.686 0.314 0.000
J43.2 Centrilobular emphysema
0.686 0.314 0.000
J43.1 Panlobular emphysema
0.686 0.314 0.000
J43.0 MacLeod's syndrome
0.686 0.314 0.000
M60-M63 Disorders of muscles
0.686 0.314 0.000
J84 Other interstitial pulmonary diseases
0.685 0.315 0.000
D46 Myelodysplastic syndromes
0.684 0.316 0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.684 0.316 0.000
X50-X57 Overexertion, travel and privation
0.683 0.317 0.000
K57.5 Diverticular disease of both small and large intestine without perforation or abscess
0.683 0.317 0.000
D73 Diseases of spleen
0.683 0.317 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.683 0.317 0.000
J18.8 Other pneumonia, organism unspecified
0.683 0.317 0.000
K76 Other diseases of liver
0.683 0.317 0.000
L92 Granulomatous disorders of skin and subcutaneous tissue
0.682 0.318 0.000
K70.4 Alcoholic hepatic failure
0.682 0.318 0.000
I70.20 Atherosclerosis of arteries of extremities (without gangrene)
0.681 0.319 0.000
K75 Other inflammatory liver diseases
0.681 0.319 0.000
Y59 Other and unspecified vaccines and biological substances
0.680 0.320 0.000
Y58 Bacterial vaccines
0.680 0.320 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.680 0.320 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.680 0.320 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.680 0.320 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.680 0.320 0.000
I72.4 Aneurysm of artery of lower extremity
0.680 0.320 0.000
K57.8 Diverticular disease of intestine, part unspecified, with perforation and abscess
0.680 0.320 0.000
Y84.6 Urinary catheterisation
0.680 0.320 0.000
L71 Rosacea
0.680 0.320 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.680 0.320 0.000
D37.9 Digestive organ, unspecified
0.679 0.321 0.000
C15.8 Overlapping lesion of oesophagus
0.679 0.321 0.000
C15.3 Upper third of oesophagus
0.679 0.321 0.000
C15.2 Abdominal part of oesophagus
0.679 0.321 0.000
C15.1 Thoracic part of oesophagus
0.679 0.321 0.000
C15.0 Cervical part of oesophagus
0.679 0.321 0.000
J11.1 Influenza with other respiratory manifestations, virus not identified
0.679 0.321 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.678 0.321 0.000
I60.1 Subarachnoid haemorrhage from middle cerebral artery
0.678 0.322 0.000
K86 Other diseases of pancreas
0.677 0.323 0.000
C41 Malignant neoplasm of bone and articular cartilage of other and unspecified sites
0.677 0.323 0.000
D41.0 Kidney
0.677 0.323 0.000
M80-M85 Disorders of bone density and structure
0.676 0.324 0.000
Y83.3 Surgical operation with formation of external stoma
0.675 0.325 0.000
K60.3 Anal fistula
0.675 0.325 0.000
D70 Agranulocytosis
0.674 0.326 0.000
C56 Malignant neoplasm of ovary
0.674 0.326 0.000
M45-M49 Spondylopathies
0.674 0.326 0.000
D41.9 Urinary organ, unspecified
0.673 0.327 0.000
D41.7 Other urinary organs
0.673 0.327 0.000
D41.3 Urethra
0.673 0.327 0.000
D41.2 Ureter
0.673 0.327 0.000
D41.1 Renal pelvis
0.673 0.327 0.000
D37.2 Small intestine
0.673 0.327 0.000
W50-W64 Exposure to animate mechanical forces
0.672 0.328 0.000
K70.0 Alcoholic fatty liver
0.672 0.328 0.000
C25.0 Head of pancreas
0.671 0.329 0.000
D59.9 Acquired haemolytic anaemia, unspecified
0.671 0.329 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.669 0.330 0.000
K90-K93 Other diseases of the digestive system
0.669 0.331 0.000
S40-S49 Injuries to the shoulder and upper arm
0.669 0.331 0.000
D58 Other hereditary haemolytic anaemias
0.669 0.331 0.000
S50-S59 Injuries to the elbow and forearm
0.668 0.332 0.000
K77 Liver disorders in diseases classified elsewhere
0.668 0.332 0.000
K71 Toxic liver disease
0.668 0.332 0.000
D37.6 Liver, gallbladder and bile ducts
0.668 0.332 0.000
Y40.0 Penicillins
0.668 0.332 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.667 0.333 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.667 0.333 0.000
J12 Viral pneumonia, not elsewhere classified
0.667 0.333 0.000
J09 Influenza due to certain identified influenza virus
0.667 0.333 0.000
Q60-Q64 Congenital malformations of the urinary system
0.667 0.333 0.000
M00-M03 Infectious arthropathies
0.667 0.333 0.000
Q80-Q89 Other congenital malformations
0.667 0.333 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.666 0.334 0.000
B02 Zoster [herpes zoster]
0.666 0.334 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.665 0.334 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.665 0.335 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.665 0.335 0.000
C94 Other leukaemias of specified cell type
0.665 0.335 0.000
C93 Monocytic leukaemia
0.665 0.335 0.000
C86 Other specified types of T/NK-cell lymphoma
0.665 0.335 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.665 0.335 0.000
L94 Other localised connective tissue disorders
0.664 0.336 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.663 0.337 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.663 0.337 0.000
I74.5 Embolism and thrombosis of iliac artery
0.662 0.338 0.000
D47.3 Essential (haemorrhagic) thrombocythaemia
0.662 0.338 0.000
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified
0.661 0.338 0.000
I62.0 Subdural haemorrhage (acute) (nontraumatic)
0.660 0.340 0.000
C66 Malignant neoplasm of ureter
0.659 0.341 0.000
K07.2 Anomalies of dental arch relationship
0.657 0.342 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.656 0.343 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.656 0.344 0.000
D75.9 Disease of blood and blood-forming organs, unspecified
0.655 0.345 0.000
C48 Malignant neoplasm of retroperitoneum and peritoneum
0.655 0.345 0.000
W05 Fall involving wheelchair
0.655 0.345 0.000
W17 Other fall from one level to another
0.655 0.345 0.000
B65-B83 Helminthiases
0.655 0.345 0.000
S20-S29 Injuries to the thorax
0.654 0.346 0.000
G30-G32 Other degenerative diseases of the nervous system
0.653 0.347 0.000
Q39 Congenital malformations of oesophagus
0.653 0.347 0.000
C92 Myeloid leukaemia
0.653 0.347 0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.651 0.349 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.651 0.349 0.000
Y48 Anaesthetics and therapeutic gases
0.650 0.350 0.000
C26.0 Intestinal tract, part unspecified
0.650 0.350 0.000
K70.2 Alcoholic fibrosis and sclerosis of liver
0.649 0.351 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.648 0.352 0.000
Q35-Q37 Cleft lip and cleft palate
0.648 0.352 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.648 0.352 0.000
K83.0 Cholangitis
0.648 0.352 0.000
V28 Motorcycle rider injured in noncollision transport accident
0.648 0.352 0.000
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.648 0.352 0.000
L87 Transepidermal elimination disorders
0.648 0.352 0.000
L88 Pyoderma gangrenosum
0.648 0.352 0.000
L86 Keratoderma in diseases classified elsewhere
0.648 0.352 0.000
L80 Vitiligo
0.648 0.352 0.000
K56.0 Paralytic ileus
0.647 0.352 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.646 0.354 0.000
V80-V89 Other land transport accidents
0.646 0.354 0.000
V40-V49 Car occupant injured in transport accident
0.645 0.354 0.000
Q43.9 Congenital malformation of intestine, unspecified
0.645 0.355 0.000
L73.2 Hidradenitis suppurativa
0.645 0.355 0.000
Y65.8 Other specified misadventures during surgical and medical care
0.644 0.356 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.644 0.356 0.000
D74 Methaemoglobinaemia
0.644 0.356 0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.644 0.356 0.000
D71 Functional disorders of polymorphonuclear neutrophils
0.644 0.356 0.000
I61 Intracerebral haemorrhage
0.644 0.356 0.000
B50-B64 Protozoal diseases
0.643 0.356 0.000
Y40.7 Antifungal antibiotics, systemically used
0.643 0.357 0.000
Y40.6 Rifamycins
0.643 0.357 0.000
Y40.5 Aminoglycosides
0.643 0.357 0.000
Y40.4 Tetracyclines
0.643 0.357 0.000
Y40.2 Chloramphenicol group
0.643 0.357 0.000
Y40.1 Cefalosporins and other -lactam antibiotics
0.643 0.357 0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.642 0.358 0.000
Q00-Q07 Congenital malformations of the nervous system
0.642 0.358 0.000
K72 Hepatic failure, not elsewhere classified
0.642 0.358 0.000
W18.3 Sports and athletics area
0.642 0.358 0.000
J00 Acute nasopharyngitis [common cold]
0.641 0.359 0.000
Q50-Q56 Congenital malformations of genital organs
0.640 0.359 0.000
K56.3 Gallstone ileus
0.640 0.360 0.000
S70-S79 Injuries to the hip and thigh
0.640 0.360 0.000
K09.0 Developmental odontogenic cysts
0.640 0.360 0.000
C25.1 Body of pancreas
0.640 0.360 0.000
K57.4 Diverticular disease of both small and large intestine with perforation and abscess
0.638 0.362 0.000
K57.0 Diverticular disease of small intestine with perforation and abscess
0.638 0.362 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.638 0.362 0.000
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system
0.638 0.362 0.000
C70 Malignant neoplasm of meninges
0.638 0.362 0.000
K76.6 Portal hypertension
0.637 0.363 0.000
K63.3 Ulcer of intestine
0.637 0.363 0.000
I72.6 Aneurysm and dissection of vertebral artery
0.637 0.363 0.000
I72.5 Aneurysm and dissection of other precerebral arteries
0.637 0.363 0.000
I72.2 Aneurysm of renal artery
0.637 0.363 0.000
I72.1 Aneurysm of artery of upper extremity
0.637 0.363 0.000
Y40.3 Macrolides
0.637 0.363 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.637 0.363 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.636 0.364 0.000
D47.2 Monoclonal gammopathy
0.636 0.364 0.000
K11.7 Disturbances of salivary secretion
0.636 0.364 0.000
K04.9 Other and unspecified diseases of pulp and periapical tissues
0.635 0.365 0.000
K10.0 Developmental disorders of jaws
0.635 0.365 0.000
K02.9 Dental caries, unspecified
0.634 0.366 0.000
K08.1 Loss of teeth due to accident, extraction or local periodontal disease
0.634 0.366 0.000
I70.1 Atherosclerosis of renal artery
0.633 0.367 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.632 0.367 0.000
M41 Scoliosis
0.632 0.368 0.000
J18.0 Bronchopneumonia, unspecified
0.631 0.369 0.000
Y79 Orthopaedic devices associated with adverse incidents
0.631 0.369 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.631 0.369 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.631 0.369 0.000
K60.5 Anorectal fistula
0.631 0.369 0.000
Y43.3 Other antineoplastic drugs
0.631 0.369 0.000
C21.8 Overlapping lesion of rectum, anus and anal canal
0.630 0.370 0.000
C21.2 Cloacogenic zone
0.630 0.370 0.000
D57 Sickle-cell disorders
0.630 0.370 0.000
D56 Thalassaemia
0.630 0.370 0.000
D55 Anaemia due to enzyme disorders
0.630 0.370 0.000
I85 Oesophageal varices
0.629 0.371 0.000
M62 Other disorders of muscle
0.629 0.371 0.000
J81 Pulmonary oedema
0.629 0.371 0.000
Y64 Contaminated medical or biological substances
0.627 0.373 0.000
Y63 Failure in dosage during surgical and medical care
0.627 0.373 0.000
Y62 Failure of sterile precautions during surgical and medical care
0.627 0.373 0.000
Y61 Foreign object accidentally left in body during surgical and medical care
0.627 0.373 0.000
Y69 Unspecified misadventure during surgical and medical care
0.627 0.373 0.000
Y66 Nonadministration of surgical and medical care
0.627 0.373 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.626 0.374 0.000
W10 Fall on and from stairs and steps
0.626 0.374 0.000
G70 Myasthenia gravis and other myoneural disorders
0.626 0.374 0.000
Y84.7 Blood-sampling
0.625 0.374 0.000
Y84.5 Insertion of gastric or duodenal sound
0.625 0.374 0.000
Y84.3 Shock therapy
0.625 0.374 0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.625 0.375 0.000
C85.0 Lymphosarcoma
0.625 0.375 0.000
K00 Disorders of tooth development and eruption
0.625 0.375 0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.624 0.376 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.624 0.376 0.000
K07.9 Dentofacial anomaly, unspecified
0.623 0.377 0.000
K07.8 Other dentofacial anomalies
0.623 0.377 0.000
K07.5 Dentofacial functional abnormalities
0.623 0.377 0.000
K07.0 Major anomalies of jaw size
0.623 0.377 0.000
W13.9 Unspecified place
0.622 0.378 0.000
L03.1 Cellulitis of other parts of limb
0.622 0.378 0.000
I85.9 Oesophageal varices without bleeding
0.622 0.378 0.000
I74.8 Embolism and thrombosis of other arteries
0.621 0.378 0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.621 0.378 0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.621 0.378 0.000
I74.0 Embolism and thrombosis of abdominal aorta
0.621 0.378 0.000
J10.1 Influenza with other respiratory manifestations, influenza virus identified
0.621 0.379 0.000
D37.7 Other digestive organs
0.620 0.379 0.000
Y57 Other and unspecified drugs and medicaments
0.620 0.379 0.000
D47.9 Neoplasm of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue, unspecified
0.620 0.380 0.000
D47.7 Other specified neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.620 0.380 0.000
D47.5 Chronic eosinophilic leukaemia [hypereosinophilic syndrome]
0.620 0.380 0.000
D47.0 Histiocytic and mast cell tumours of uncertain and unknown behaviour
0.620 0.380 0.000
K56.1 Intussusception
0.620 0.380 0.000
L03.0 Cellulitis of finger and toe
0.620 0.380 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.619 0.381 0.000
W19 Unspecified fall
0.619 0.381 0.000
W16 Diving or jumping into water causing injury other than drowning or submersion
0.619 0.381 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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