TreeWAS – Variant ID: rs11622475

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
C78.0 Secondary malignant neoplasm of lung	0.000	0.835	0.165
C78 Secondary malignant neoplasm of respiratory and digestive organs	0.000	0.838	0.162
C78.7 Secondary malignant neoplasm of liver	0.000	0.843	0.157
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs	0.000	0.848	0.152
C79 Secondary malignant neoplasm of other sites	0.000	0.850	0.150
C79.3 Secondary malignant neoplasm of brain and cerebral meninges	0.000	0.851	0.149
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.000	0.854	0.146
C79.8 Secondary malignant neoplasm of other specified sites	0.000	0.856	0.144
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.000	0.870	0.130
C79.0 Secondary malignant neoplasm of kidney and renal pelvis	0.000	0.870	0.130
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs	0.000	0.870	0.130
T43.2 Other and unspecified antidepressants	0.000	0.871	0.129
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system	0.000	0.875	0.125
Z49.1 Extracorporeal dialysis	0.125	0.875	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.000	0.875	0.125
T43.5 Other and unspecified antipsychotics and neuroleptics	0.000	0.884	0.116
C80 Malignant neoplasm without specification of site	0.000	0.885	0.115
T43.6 Psychostimulants with abuse potential	0.000	0.885	0.115
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs	0.000	0.888	0.112
C78.4 Secondary malignant neoplasm of small intestine	0.000	0.893	0.107
Z49 Care involving dialysis	0.106	0.894	0.000
C78.1 Secondary malignant neoplasm of mediastinum	0.000	0.898	0.102
C79.2 Secondary malignant neoplasm of skin	0.000	0.899	0.101
C76 Malignant neoplasm of other and ill-defined sites	0.000	0.900	0.100
C79.9 Secondary malignant neoplasm, unspecified site	0.000	0.900	0.100
T43.3 Phenothiazine antipsychotics and neuroleptics	0.000	0.900	0.100
T43.4 Butyrophenone and thioxanthene neuroleptics	0.000	0.901	0.099
Z49.0 Preparatory care for dialysis	0.098	0.902	0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum	0.000	0.906	0.094
T43.9 Psychotropic drug, unspecified	0.000	0.906	0.094
T43.8 Other psychotropic drugs, not elsewhere classified	0.000	0.906	0.094
Z49.2 Other dialysis	0.094	0.906	0.000
C80.0 Malignant neoplasm, primary site unknown, so stated	0.000	0.910	0.090
C78.5 Secondary malignant neoplasm of large intestine and rectum	0.000	0.911	0.089
C80.9 Malignant neoplasm, unspecified	0.000	0.913	0.087
C79.7 Secondary malignant neoplasm of adrenal gland	0.000	0.913	0.087
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.000	0.916	0.084
C76.0 Head, face and neck	0.000	0.919	0.081
T36-T50 Poisoning by drugs, medicaments and biological substances	0.000	0.921	0.079
C76.8 Overlapping lesion of other and ill-defined sites	0.000	0.928	0.072
C76.7 Other ill-defined sites	0.000	0.928	0.072
C76.5 Lower limb	0.000	0.928	0.072
C76.4 Upper limb	0.000	0.928	0.072
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.000	0.929	0.071
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.000	0.930	0.070
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.000	0.931	0.069
C78.2 Secondary malignant neoplasm of pleura	0.000	0.932	0.068
C76.3 Pelvis	0.000	0.932	0.068
T39.0 Salicylates	0.000	0.933	0.067
C76.2 Abdomen	0.000	0.933	0.067
T46 Poisoning by agents primarily affecting the cardiovascular system	0.000	0.934	0.066
C76.1 Thorax	0.000	0.934	0.065
C79.6 Secondary malignant neoplasm of ovary	0.000	0.936	0.064
T47.1 Other antacids and anti-gastric-secretion drugs	0.000	0.936	0.064
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.000	0.940	0.060
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.000	0.941	0.059
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.000	0.942	0.058
T42.1 Iminostilbenes	0.000	0.942	0.058
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.000	0.943	0.057
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.000	0.943	0.057
T41 Poisoning by anaesthetics and therapeutic gases	0.000	0.943	0.057
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.000	0.944	0.056
T42.4 Benzodiazepines	0.000	0.945	0.055
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.000	0.946	0.053
J03.9 Acute tonsillitis, unspecified	0.051	0.949	0.000
T39.4 Antirheumatics, not elsewhere classified	0.000	0.949	0.051
T39.2 Pyrazolone derivatives	0.000	0.949	0.051
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.000	0.950	0.050
T47.8 Other agents primarily affecting the gastro-intestinal system	0.000	0.950	0.050
T47.7 Emetics	0.000	0.950	0.050
T47.6 Antidiarrhoeal drugs	0.000	0.950	0.050
T47.5 Digestants	0.000	0.950	0.050
T47.4 Other laxatives	0.000	0.950	0.050
T47.3 Saline and osmotic laxatives	0.000	0.950	0.050
T47.2 Stimulant laxatives	0.000	0.950	0.050
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.000	0.950	0.050
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.000	0.950	0.050
T42.5 Mixed antiepileptics, not elsewhere classified	0.000	0.950	0.050
T42.3 Barbiturates	0.000	0.950	0.050
T42.2 Succinimides and oxazolidinediones	0.000	0.950	0.050
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.000	0.952	0.048
T47.0 Histamine H(2)-receptor antagonists	0.000	0.952	0.048
T36 Poisoning by systemic antibiotics	0.000	0.952	0.048
T46.3 Coronary vasodilators, not elsewhere classified	0.000	0.952	0.047
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.000	0.953	0.047
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.000	0.953	0.047
T46.8 Antivaricose drugs, including sclerosing agents	0.000	0.953	0.047
T46.7 Peripheral vasodilators	0.000	0.953	0.047
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.000	0.953	0.047
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.000	0.953	0.047
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.000	0.953	0.047
T46.4 Angiotensin-converting-enzyme inhibitors	0.000	0.954	0.046
T46.1 Calcium-channel blockers	0.000	0.954	0.046
T46.5 Other antihypertensive drugs, not elsewhere classified	0.000	0.955	0.045
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.000	0.956	0.044
T42.0 Hydantoin derivatives	0.000	0.957	0.043
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.958	0.042
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.000	0.959	0.041
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.000	0.959	0.041
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.959	0.041
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.000	0.959	0.041
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.000	0.959	0.041
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.000	0.959	0.041
T44.1 Other parasympathomimetics [cholinergics]	0.000	0.959	0.041
T44.0 Anticholinesterase agents	0.000	0.959	0.041
T41.5 Therapeutic gases	0.000	0.959	0.041
T41.4 Anaesthetic, unspecified	0.000	0.959	0.041
T41.3 Local anaesthetics	0.000	0.959	0.041
T41.2 Other and unspecified general anaesthetics	0.000	0.959	0.041
T41.1 Intravenous anaesthetics	0.000	0.959	0.041
T41.0 Inhaled anaesthetics	0.000	0.959	0.041
T49.9 Topical agent, unspecified	0.000	0.959	0.041
T49.8 Other topical agents	0.000	0.959	0.041
T49.7 Dental drugs, topically applied	0.000	0.959	0.041
T49.6 Otorhinolaryngological drugs and preparations	0.000	0.959	0.041
T49.5 Ophthalmological drugs and preparations	0.000	0.959	0.041
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.000	0.959	0.041
T49.3 Emollients, demulcents and protectants	0.000	0.959	0.041
T49.2 Local astringents and local detergents	0.000	0.959	0.041
T49.1 Antipruritics	0.000	0.959	0.041
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.000	0.959	0.041
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.000	0.959	0.041
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.000	0.959	0.041
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.000	0.959	0.041
T37.5 Antiviral drugs	0.000	0.959	0.041
T37.4 Anthelminthics	0.000	0.959	0.041
T37.3 Other antiprotozoal drugs	0.000	0.959	0.041
T37.2 Antimalarials and drugs acting on other blood protozoa	0.000	0.959	0.041
T37.1 Antimycobacterial drugs	0.000	0.959	0.041
T37.0 Sulphonamides	0.000	0.959	0.041
T37.8 Other specified systemic anti-infectives and antiparasitics	0.000	0.960	0.040
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.000	0.961	0.038
T48.6 Antiasthmatics, not elsewhere classified	0.000	0.961	0.038
T48.4 Expectorants	0.000	0.961	0.038
T48.3 Antitussives	0.000	0.961	0.038
T48.2 Other and unspecified agents primarily acting on muscles	0.000	0.961	0.038
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.000	0.961	0.038
T48.0 Oxytocic drugs	0.000	0.961	0.038
D86.9 Sarcoidosis, unspecified	0.000	0.962	0.038
T45.2 Vitamins, not elsewhere classified	0.000	0.963	0.036
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.000	0.964	0.036
T40.2 Other opioids	0.000	0.965	0.035
T48.5 Anti-common-cold drugs	0.000	0.965	0.035
T36.9 Systemic antibiotic, unspecified	0.000	0.965	0.034
T36.8 Other systemic antibiotics	0.000	0.965	0.034
T36.7 Antifungal antibiotics, systemically used	0.000	0.965	0.034
T36.6 Rifamycins	0.000	0.965	0.034
T36.5 Aminoglycosides	0.000	0.965	0.034
T36.3 Macrolides	0.000	0.965	0.034
T36.2 Chloramphenicol group	0.000	0.965	0.034
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.000	0.965	0.034
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.000	0.965	0.034
I38 Endocarditis, valve unspecified	0.000	0.966	0.034
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.000	0.966	0.034
T40.8 Lysergide [LSD]	0.000	0.966	0.034
T40.7 Cannabis (derivatives)	0.000	0.966	0.034
T40.5 Cocaine	0.000	0.966	0.034
T40.3 Methadone	0.000	0.966	0.034
T40.1 Heroin	0.000	0.966	0.034
T40.0 Opium	0.000	0.966	0.034
T50.7 Analeptics and opioid receptor antagonists	0.000	0.966	0.034
T50.6 Antidotes and chelating agents, not elsewhere classified	0.000	0.966	0.034
T50.5 Appetite depressants	0.000	0.966	0.034
T50.3 Electrolytic, caloric and water-balance agents	0.000	0.966	0.034
T50.1 Loop [high-ceiling] diuretics	0.000	0.966	0.034
T50.0 Mineralocorticoids and their antagonists	0.000	0.966	0.034
T50.8 Diagnostic agents	0.000	0.967	0.033
T50.4 Drugs affecting uric acid metabolism	0.000	0.967	0.033
T40.4 Other synthetic narcotics	0.000	0.967	0.033
T36.0 Penicillins	0.000	0.967	0.033
J03 Acute tonsillitis	0.032	0.968	0.000
T39.1 4-Aminophenol derivatives	0.000	0.968	0.032
T45.9 Primarily systemic and haematological agent, unspecified	0.000	0.968	0.032
T45.8 Other primarily systemic and haematological agents	0.000	0.968	0.032
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.000	0.968	0.032
T45.6 Fibrinolysis-affecting drugs	0.000	0.968	0.032
T45.4 Iron and its compounds	0.000	0.968	0.032
T45.3 Enzymes, not elsewhere classified	0.000	0.968	0.032
T45.0 Antiallergic and antiemetic drugs	0.000	0.969	0.031
T36.4 Tetracyclines	0.000	0.971	0.028
T38.1 Thyroid hormones and substitutes	0.000	0.972	0.028
Z99.3 Dependence on wheelchair	0.027	0.973	0.000
T38.9 Other and unspecified hormone antagonists	0.000	0.974	0.026
T38.7 Androgens and anabolic congeners	0.000	0.974	0.026
T38.5 Other oestrogens and progestogens	0.000	0.974	0.026
T38.4 Oral contraceptives	0.000	0.974	0.026
T38.2 Antithyroid drugs	0.000	0.974	0.026
D86 Sarcoidosis	0.000	0.974	0.026
T38.8 Other and unspecified hormones and their synthetic substitutes	0.000	0.974	0.025
T40.6 Other and unspecified narcotics	0.000	0.976	0.024
T50.9 Other and unspecified drugs, medicaments and biological substances	0.000	0.976	0.024
J03.8 Acute tonsillitis due to other specified organisms	0.023	0.976	0.000
J03.0 Streptococcal tonsillitis	0.023	0.976	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.000	0.977	0.023
D86.8 Sarcoidosis of other and combined sites	0.000	0.977	0.023
T45.5 Anticoagulants	0.000	0.977	0.023
T38.0 Glucocorticoids and synthetic analogues	0.000	0.977	0.022
D86.0 Sarcoidosis of lung	0.000	0.977	0.022
D86.3 Sarcoidosis of skin	0.000	0.980	0.020
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.001	0.980	0.020
M18.9 Arthrosis of first carpometacarpal joint, unspecified	0.020	0.980	0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow	0.000	0.980	0.020
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.000	0.981	0.019
J00-J06 Acute upper respiratory infections	0.019	0.981	0.000
F31.9 Bipolar affective disorder, unspecified	0.000	0.981	0.019
J02 Acute pharyngitis	0.019	0.981	0.000
N48.1 Balanoposthitis	0.018	0.982	0.000
S01.5 Open wound of lip and oral cavity	0.018	0.982	0.000
F31 Bipolar affective disorder	0.000	0.982	0.018
J02.9 Acute pharyngitis, unspecified	0.018	0.982	0.000
J05 Acute obstructive laryngitis [croup] and epiglottitis	0.017	0.983	0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.000	0.983	0.017
F31.0 Bipolar affective disorder, current episode hypomanic	0.000	0.984	0.016
J05.1 Acute epiglottitis	0.016	0.984	0.000
J02.8 Acute pharyngitis due to other specified organisms	0.015	0.985	0.000
D86.1 Sarcoidosis of lymph nodes	0.000	0.985	0.015
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.000	0.985	0.015
J02.0 Streptococcal pharyngitis	0.015	0.985	0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.000	0.985	0.015
F31.6 Bipolar affective disorder, current episode mixed	0.000	0.985	0.015
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.000	0.986	0.014
K40.2 Bilateral inguinal hernia, without obstruction or gangrene	0.014	0.986	0.000
J04 Acute laryngitis and tracheitis	0.013	0.987	0.000
F31.7 Bipolar affective disorder, currently in remission	0.000	0.987	0.013
K43.0 Ventral hernia with obstruction, without gangrene	0.013	0.987	0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.000	0.987	0.013
J32.0 Chronic maxillary sinusitis	0.000	0.987	0.013
K43 Ventral hernia	0.013	0.987	0.000
J05.0 Acute obstructive laryngitis [croup]	0.012	0.988	0.000
F31.8 Other bipolar affective disorders	0.000	0.988	0.012
J01 Acute sinusitis	0.012	0.988	0.000
J32 Chronic sinusitis	0.000	0.988	0.012
J32.9 Chronic sinusitis, unspecified	0.000	0.988	0.012
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms	0.000	0.988	0.012
K46.9 Unspecified abdominal hernia without obstruction or gangrene	0.012	0.988	0.000
K40 Inguinal hernia	0.012	0.988	0.000
S01 Open wound of head	0.012	0.988	0.000
K46 Unspecified abdominal hernia	0.012	0.988	0.000
K40-K46 Hernia	0.011	0.989	0.000
K40.3 Unilateral or unspecified inguinal hernia, with obstruction, without gangrene	0.011	0.989	0.000
J06 Acute upper respiratory infections of multiple and unspecified sites	0.011	0.989	0.000
S01.8 Open wound of other parts of head	0.011	0.989	0.000
S01.2 Open wound of nose	0.011	0.989	0.000
K43.9 Ventral hernia without obstruction or gangrene	0.011	0.989	0.000
J32.4 Chronic pansinusitis	0.000	0.989	0.011
J04.1 Acute tracheitis	0.010	0.990	0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified	0.010	0.990	0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes	0.000	0.990	0.010
S01.4 Open wound of cheek and temporomandibular area	0.010	0.990	0.000
C77.4 Inguinal and lower limb lymph nodes	0.000	0.990	0.010
J04.2 Acute laryngotracheitis	0.010	0.990	0.000
J32.8 Other chronic sinusitis	0.000	0.990	0.010
K45 Other abdominal hernia	0.010	0.990	0.000
J32.3 Chronic sphenoidal sinusitis	0.000	0.990	0.010
J43.9 Emphysema, unspecified	0.000	0.991	0.009
K43.7 Other and unspecified ventral hernia with gangrene	0.009	0.991	0.000
K43.6 Other and unspecified ventral hernia with obstruction, without gangrene	0.009	0.991	0.000
K43.5 Parastomal hernia without obstruction or gangrene	0.009	0.991	0.000
K43.4 Parastomal hernia with gangrene	0.009	0.991	0.000
K43.3 Parastomal hernia with obstruction, without gangrene	0.009	0.991	0.000
K43.2 Incisional hernia without obstruction or gangrene	0.009	0.991	0.000
K43.1 Ventral hernia with gangrene	0.009	0.991	0.000
J32.1 Chronic frontal sinusitis	0.000	0.991	0.009
J01.0 Acute maxillary sinusitis	0.009	0.991	0.000
Z99.2 Dependence on renal dialysis	0.009	0.991	0.000
K46.0 Unspecified abdominal hernia with obstruction, without gangrene	0.009	0.991	0.000
J01.4 Acute pansinusitis	0.009	0.991	0.000
J01.3 Acute sphenoidal sinusitis	0.009	0.991	0.000
J01.2 Acute ethmoidal sinusitis	0.009	0.991	0.000
J01.1 Acute frontal sinusitis	0.009	0.991	0.000
J04.0 Acute laryngitis	0.009	0.991	0.000
Z91.6 Personal history of other physical trauma	0.009	0.991	0.000
K42.0 Umbilical hernia with obstruction, without gangrene	0.009	0.991	0.000
K45.8 Other specified abdominal hernia without obstruction or gangrene	0.009	0.991	0.000
K40.1 Bilateral inguinal hernia, with gangrene	0.009	0.991	0.000
K42 Umbilical hernia	0.009	0.991	0.000
S01.1 Open wound of eyelid and periocular area	0.009	0.991	0.000
K46.1 Unspecified abdominal hernia with gangrene	0.008	0.991	0.000
J01.8 Other acute sinusitis	0.008	0.991	0.000
K40.4 Unilateral or unspecified inguinal hernia, with gangrene	0.008	0.992	0.000
J06.8 Other acute upper respiratory infections of multiple sites	0.008	0.992	0.000
J06.0 Acute laryngopharyngitis	0.008	0.992	0.000
S01.7 Multiple open wounds of head	0.008	0.992	0.000
C77.8 Lymph nodes of multiple regions	0.000	0.992	0.008
Z99.9 Dependence on unspecified enabling machine and device	0.008	0.992	0.000
Z99.4 Dependence on artificial heart	0.008	0.992	0.000
Z99.0 Dependence on aspirator	0.008	0.992	0.000
J01.9 Acute sinusitis, unspecified	0.008	0.992	0.000
M18 Arthrosis of first carpometacarpal joint	0.008	0.992	0.000
K45.0 Other specified abdominal hernia with obstruction, without gangrene	0.007	0.992	0.000
J32.2 Chronic ethmoidal sinusitis	0.000	0.992	0.007
Z99.1 Dependence on respirator	0.007	0.993	0.000
K45.1 Other specified abdominal hernia with gangrene	0.007	0.993	0.000
J33.9 Nasal polyp, unspecified	0.000	0.993	0.007
R85.5 Abnormal microbiological findings	0.007	0.993	0.000
K42.1 Umbilical hernia with gangrene	0.006	0.993	0.000
S01.3 Open wound of ear	0.006	0.993	0.000
K40.0 Bilateral inguinal hernia, with obstruction, without gangrene	0.006	0.994	0.000
S01.9 Open wound of head, part unspecified	0.006	0.994	0.000
C77.2 Intra-abdominal lymph nodes	0.000	0.994	0.006
M18.1 Other primary arthrosis of first carpometacarpal joint	0.006	0.994	0.000
J06.9 Acute upper respiratory infection, unspecified	0.006	0.994	0.000
M18.5 Other secondary arthrosis of first carpometacarpal joint	0.006	0.994	0.000
M18.4 Other secondary arthrosis of first carpometacarpal joints, bilateral	0.006	0.994	0.000
M18.3 Other posttraumatic arthrosis of first carpometacarpal joint	0.006	0.994	0.000
M18.2 Posttraumatic arthrosis of first carpometacarpal joints, bilateral	0.006	0.994	0.000
R93.1 Abnormal findings on diagnostic imaging of heart and coronary circulation	0.000	0.994	0.006
C77.1 Intrathoracic lymph nodes	0.000	0.994	0.006
F17.1 Harmful use	0.000	0.994	0.006
Z43.3 Attention to colostomy	0.006	0.994	0.000
R93.8 Abnormal findings on diagnostic imaging of other specified body structures	0.000	0.995	0.005
U51.1 Previously admitted to a psychiatric hospital of the provider	0.000	0.995	0.005
K41 Femoral hernia	0.005	0.995	0.000
Z99.8 Dependence on other enabling machines and devices	0.005	0.995	0.000
G54.9 Nerve root and plexus disorder, unspecified	0.000	0.995	0.005
N48.2 Other inflammatory disorders of penis	0.005	0.995	0.000
N48 Other disorders of penis	0.005	0.995	0.000
R85 Abnormal findings in specimens from digestive organs and abdominal cavity	0.005	0.995	0.000
M18.0 Primary arthrosis of first carpometacarpal joints, bilateral	0.004	0.995	0.000
Z89.5 Acquired absence of leg at or below knee	0.005	0.995	0.000
L98.8 Other specified disorders of skin and subcutaneous tissue	0.005	0.995	0.000
S01.0 Open wound of scalp	0.004	0.995	0.000
R93 Abnormal findings on diagnostic imaging of other body structures	0.000	0.996	0.004
Y40.0 Penicillins	0.004	0.996	0.000
U51 Admission status on psychiatric patients	0.000	0.996	0.004
N48.9 Disorder of penis, unspecified	0.004	0.996	0.000
N48.3 Priapism	0.004	0.996	0.000
H11.0 Pterygium	0.000	0.996	0.004
K41.4 Unilateral or unspecified femoral hernia, with gangrene	0.004	0.996	0.000
K41.2 Bilateral femoral hernia, without obstruction or gangrene	0.004	0.996	0.000
K41.1 Bilateral femoral hernia, with gangrene	0.004	0.996	0.000
K41.0 Bilateral femoral hernia, with obstruction, without gangrene	0.004	0.996	0.000
U51.0 Not Previously admitted to a psyciatric hospital	0.000	0.996	0.004
R85.7 Abnormal histological findings	0.004	0.996	0.000
R93.2 Abnormal findings on diagnostic imaging of liver and biliary tract	0.000	0.996	0.004
S05.1 Contusion of eyeball and orbital tissues	0.004	0.996	0.000
T92.1 Sequelae of fracture of arm	0.004	0.996	0.000
Y40.3 Macrolides	0.004	0.996	0.000
M62.80 Other specified disorders of muscle (Multiple sites)	0.000	0.996	0.004
K41.3 Unilateral or unspecified femoral hernia, with obstruction, without gangrene	0.004	0.996	0.000
M62.85 Other specified disorders of muscle (Pelvic region and thigh)	0.000	0.996	0.004
D61.9 Aplastic anaemia, unspecified	0.000	0.996	0.004
R93.6 Abnormal findings on diagnostic imaging of limbs	0.000	0.996	0.004
J43 Emphysema	0.000	0.996	0.004
N48.5 Ulcer of penis	0.004	0.996	0.000
C77.9 Lymph node, unspecified	0.000	0.996	0.004
R93.5 Abnormal findings on diagnostic imaging of other abdominal regions, including retroperitoneum	0.000	0.996	0.004
R85.8 Other abnormal findings	0.004	0.996	0.000
M84.07 Malunion of fracture (Ankle and foot)	0.004	0.996	0.000
S05.0 Injury of conjunctiva and corneal abrasion without mention of foreign body	0.004	0.996	0.000
M62.8 Other specified disorders of muscle	0.000	0.996	0.004
I49.9 Cardiac arrhythmia, unspecified	0.000	0.996	0.004
R85.9 Unspecified abnormal finding	0.004	0.996	0.000
Y40 Systemic antibiotics	0.004	0.996	0.000
K44 Diaphragmatic hernia	0.004	0.996	0.000
R85.6 Abnormal cytological findings	0.003	0.996	0.000
R85.4 Abnormal immunological findings	0.003	0.996	0.000
R85.3 Abnormal level of substances chiefly nonmedicinal as to source	0.003	0.996	0.000
R85.2 Abnormal level of other drugs, medicaments and biological substances	0.003	0.996	0.000
R85.1 Abnormal level of hormones	0.003	0.996	0.000
R85.0 Abnormal level of enzymes	0.003	0.996	0.000
D80-D89 Certain disorders involving the immune mechanism	0.000	0.997	0.003
S05 Injury of eye and orbit	0.003	0.997	0.000
M84.0 Malunion of fracture	0.003	0.997	0.000
U51.2 Previously admitted to a psychiatric hospital of another provider	0.000	0.997	0.003
M62.89 Other specified disorders of muscle (Site unspecified)	0.000	0.997	0.003
Y40.7 Antifungal antibiotics, systemically used	0.003	0.997	0.000
M84.01 Malunion of fracture (Shoulder region)	0.003	0.997	0.000
C77.5 Intrapelvic lymph nodes	0.000	0.997	0.003
R93.7 Abnormal findings on diagnostic imaging of other parts of musculoskeletal system	0.000	0.997	0.003
Y40.8 Other systemic antibiotics	0.003	0.997	0.000
M62.88 Other specified disorders of muscle (Other)	0.000	0.997	0.003
J00 Acute nasopharyngitis [common cold]	0.003	0.997	0.000
Z89 Acquired absence of limb	0.003	0.997	0.000
S05.5 Penetrating wound of eyeball with foreign body	0.003	0.997	0.000
M84.06 Malunion of fracture (Lower leg)	0.003	0.997	0.000
U88 Agent resistant to multiple antibiotics	0.003	0.997	0.000
M84.04 Malunion of fracture (Hand)	0.003	0.997	0.000
J43.1 Panlobular emphysema	0.000	0.997	0.003
J43.0 MacLeod's syndrome	0.000	0.997	0.003
J43.2 Centrilobular emphysema	0.000	0.997	0.003
E27.4 Other and unspecified adrenocortical insufficiency	0.003	0.997	0.000
Z89.6 Acquired absence of leg above knee	0.003	0.997	0.000
M62.83 Other specified disorders of muscle (Forearm)	0.000	0.997	0.003
M62.87 Other specified disorders of muscle (Ankle and foot)	0.000	0.997	0.003
N48.4 Impotence of organic origin	0.003	0.997	0.000
H50.9 Strabismus, unspecified	0.000	0.997	0.003
M62.86 Other specified disorders of muscle (Lower leg)	0.000	0.997	0.003
Y40.6 Rifamycins	0.003	0.997	0.000
Y40.4 Tetracyclines	0.003	0.997	0.000
Y40.2 Chloramphenicol group	0.003	0.997	0.000
D83 Common variable immunodeficiency	0.000	0.997	0.003
J33 Nasal polyp	0.000	0.997	0.003
J43.8 Other emphysema	0.000	0.997	0.003
M62.84 Other specified disorders of muscle (Hand)	0.000	0.997	0.003
R93.0 Abnormal findings on diagnostic imaging of skull and head, not elsewhere classified	0.000	0.997	0.003
S05.6 Penetrating wound of eyeball without foreign body	0.003	0.997	0.000
M62.81 Other specified disorders of muscle (Shoulder region)	0.000	0.997	0.003
M84.03 Malunion of fracture (Forearm)	0.003	0.997	0.000
S05.7 Avulsion of eye	0.003	0.997	0.000
S05.4 Penetrating wound of orbit with or without foreign body	0.003	0.997	0.000
S05.3 Ocular laceration without prolapse or loss of intraocular tissue	0.003	0.997	0.000
Y40.5 Aminoglycosides	0.003	0.997	0.000
D81 Combined immunodeficiencies	0.000	0.997	0.003
Y40.9 Systemic antibiotic, unspecified	0.003	0.997	0.000
M84.09 Malunion of fracture (Site unspecified)	0.003	0.997	0.000
M84.08 Malunion of fracture (Other)	0.003	0.997	0.000
M84.00 Malunion of fracture (Multiple sites)	0.003	0.997	0.000
Z88.9 Personal history of allergy to unspecified drugs, medicaments and biological substances	0.000	0.997	0.003
M84.05 Malunion of fracture (Pelvic region and thigh)	0.003	0.997	0.000
J33.8 Other polyp of sinus	0.000	0.997	0.003
R03.1 Nonspecific low blood-pressure reading	0.003	0.997	0.000
Z89.7 Acquired absence of both lower limbs [any level, except toes alone]	0.003	0.997	0.000
M62.82 Other specified disorders of muscle (Upper arm)	0.000	0.997	0.003
D82 Immunodeficiency associated with other major defects	0.000	0.997	0.002
Z89.8 Acquired absence of upper and lower limbs [any level]	0.003	0.997	0.000
S05.2 Ocular laceration and rupture with prolapse or loss of intraocular tissue	0.002	0.997	0.000
Z89.4 Acquired absence of foot and ankle	0.003	0.997	0.000
S42.30 Fracture of shaft of humerus (closed)	0.003	0.997	0.000
C77.3 Axillary and upper limb lymph nodes	0.000	0.997	0.003
K44.0 Diaphragmatic hernia with obstruction, without gangrene	0.002	0.997	0.000
S00-S09 Injuries to the head	0.003	0.997	0.000
Z89.2 Acquired absence of upper limb above wrist	0.002	0.997	0.000
K44.1 Diaphragmatic hernia with gangrene	0.002	0.997	0.000
Z89.9 Acquired absence of limb, unspecified	0.002	0.997	0.000
Z89.3 Acquired absence of both upper limbs [any level]	0.002	0.997	0.000
Z89.1 Acquired absence of hand and wrist	0.002	0.997	0.000
N97.9 Female infertility, unspecified	0.000	0.998	0.002
D83.9 Common variable immunodeficiency, unspecified	0.000	0.998	0.002
J69.0 Pneumonitis due to food and vomit	0.002	0.998	0.000
M34.1 CR(E)ST syndrome	0.000	0.998	0.002
M84.02 Malunion of fracture (Upper arm)	0.002	0.998	0.000
Z43 Attention to artificial openings	0.002	0.998	0.000
R93.4 Abnormal findings on diagnostic imaging of urinary organs	0.000	0.998	0.002
D83.8 Other common variable immunodeficiencies	0.000	0.998	0.002
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells	0.000	0.998	0.002
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders	0.000	0.998	0.002
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function	0.000	0.998	0.002
J33.1 Polypoid sinus degeneration	0.000	0.998	0.002
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.002
Z43.5 Attention to cyctostomy	0.002	0.998	0.000
Z43.1 Attention to gastrostomy	0.002	0.998	0.000
Z43.6 Attention to other artificial openings of urinary tract	0.002	0.998	0.000
C20 Malignant neoplasm of rectum	0.000	0.998	0.002
D17.6 Benign lipomatous neoplasm of spermatic cord	0.000	0.998	0.002
D81.9 Combined immunodeficiency, unspecified	0.000	0.998	0.002
D81.8 Other combined immunodeficiencies	0.000	0.998	0.002
D81.7 Major histocompatibility complex class II deficiency	0.000	0.998	0.002
D81.6 Major histocompatibility complex class I deficiency	0.000	0.998	0.002
D81.5 Purine nucleoside phosphorylase [PNP] deficiency	0.000	0.998	0.002
D81.4 Nezelof's syndrome	0.000	0.998	0.002
D81.3 Adenosine deaminase [ADA] deficiency	0.000	0.998	0.002
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers	0.000	0.998	0.002
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers	0.000	0.998	0.002
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis	0.000	0.998	0.002
N04.9 Unspecified	0.000	0.998	0.002
O61.0 Failed medical induction of labour	0.002	0.998	0.000
N48.8 Other specified disorders of penis	0.002	0.998	0.000
S03 Dislocation, sprain and strain of joints and ligaments of head	0.002	0.998	0.000
D82.9 Immunodeficiency associated with major defect, unspecified	0.000	0.998	0.002
D82.8 Immunodeficiency associated with other specified major defects	0.000	0.998	0.002
D82.4 Hyperimmunoglobulin E [IgE] syndrome	0.000	0.998	0.002
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus	0.000	0.998	0.002
D82.2 Immunodeficiency with short-limbed stature	0.000	0.998	0.002
D82.0 Wiskott-Aldrich syndrome	0.000	0.998	0.002
F17 Mental and behavioural disorders due to use of tobacco	0.000	0.998	0.002
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.000	0.998	0.002
S05.8 Other injuries of eye and orbit	0.002	0.998	0.000
M72.04 Palmar fascial fibromatosis [Dupuytren]-Hand	0.002	0.998	0.000
S62.00 Fracture of navicular [scaphoid] bone of hand (closed)	0.000	0.998	0.002
S05.9 Injury of eye and orbit, part unspecified	0.002	0.998	0.000
S08 Traumatic amputation of part of head	0.002	0.998	0.000
S07 Crushing injury of head	0.002	0.998	0.000
S04 Injury of cranial nerves	0.002	0.998	0.000
D82.1 Di George's syndrome	0.000	0.998	0.002
N48.0 Leukoplakia of penis	0.002	0.998	0.000
D84 Other immunodeficiencies	0.000	0.998	0.002
I06.0 Rheumatic aortic stenosis	0.002	0.998	0.000
D80 Immunodeficiency with predominantly antibody defects	0.000	0.998	0.002
M84 Disorders of continuity of bone	0.002	0.998	0.000
M84.83 Other disorders of continuity of bone (Forearm)	0.002	0.998	0.000
S42.3 Fracture of shaft of humerus	0.002	0.998	0.000
R80 Isolated proteinuria	0.000	0.998	0.002
I87.8 Other specified disorders of veins	0.000	0.998	0.002
M84.8 Other disorders of continuity of bone	0.002	0.998	0.000
Z89.0 Acquired absence of finger(s) [including thumb], unilateral	0.002	0.998	0.000
M25.66 Stiffness of joint, not elsewhere classified (Lower leg)	0.000	0.998	0.002
K25.3 Acute without haemorrhage or perforation	0.002	0.998	0.000
S03.2 Dislocation of tooth	0.002	0.998	0.000
Z43.4 Attention to other artificial openings of digestive tract	0.002	0.998	0.000
Z43.9 Attention to unspecified artificial opening	0.002	0.998	0.000
Z43.7 Attention to artificial vagina	0.002	0.998	0.000
H46 Optic neuritis	0.002	0.998	0.000
U80.1 Methicillin resistant agent	0.000	0.998	0.002
D61 Other aplastic anaemias	0.000	0.998	0.002
S12.70 Multiple fractures of cervical spine (closed)	0.002	0.998	0.000
Y40.1 Cefalosporins and other -lactam antibiotics	0.002	0.998	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.000	0.998	0.002
U80 Agent resistant to penicillin and related antibiotics	0.000	0.998	0.002
F17.2 Dependence syndrome	0.000	0.998	0.002

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations