TreeWAS – Variant ID: rs116369005

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M06.9 Rheumatoid arthritis, unspecified	1.000	0.000	0.000
J33 Nasal polyp	1.000	0.000	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	1.000	0.000	0.000
# Top node	1.000	0.000	0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	1.000	0.000	0.000
M05-M14 Inflammatory polyarthropathies	1.000	0.000	0.000
J33.9 Nasal polyp, unspecified	1.000	0.000	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	1.000	0.000	0.000
M06 Other rheumatoid arthritis	1.000	0.000	0.000
Chapter X Diseases of the respiratory system	1.000	0.000	0.000
M35.3 Polymyalgia rheumatica	1.000	0.000	0.000
J30-J39 Other diseases of upper respiratory tract	1.000	0.000	0.000
M20-M25 Other joint disorders	1.000	0.000	0.000
M35 Other systemic involvement of connective tissue	1.000	0.000	0.000
E00-E07 Disorders of thyroid gland	0.999	0.001	0.000
E03 Other hypothyroidism	0.999	0.001	0.000
K50-K52 Noninfective enteritis and colitis	0.000	0.002	0.998
K51 Ulcerative colitis	0.000	0.002	0.998
E03.9 Hypothyroidism, unspecified	0.998	0.002	0.000
Chapter XI Diseases of the digestive system	0.000	0.002	0.998
K55-K64 Other diseases of intestines	0.000	0.003	0.997
K51.9 Ulcerative colitis, unspecified	0.000	0.003	0.997
J45.9 Asthma, unspecified	0.996	0.004	0.000
J40-J47 Chronic lower respiratory diseases	0.996	0.004	0.000
J45 Asthma	0.996	0.004	0.000
J33.0 Polyp of nasal cavity	0.995	0.005	0.000
M05 Seropositive rheumatoid arthritis	0.995	0.005	0.000
K90-K93 Other diseases of the digestive system	0.000	0.006	0.994
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.994	0.006	0.000
K90 Intestinal malabsorption	0.000	0.007	0.993
K90.0 Coeliac disease	0.000	0.008	0.992
M05.9 Seropositive rheumatoid arthritis, unspecified	0.991	0.009	0.000
K62 Other diseases of anus and rectum	0.000	0.010	0.990
E10-E14 Diabetes mellitus	0.989	0.011	0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.982	0.018	0.000
K63 Other diseases of intestine	0.000	0.019	0.981
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.979	0.021	0.000
Z95 Presence of cardiac and vascular implants and grafts	0.978	0.022	0.000
Chapter XXI Factors influencing health status and contact with health services	0.977	0.023	0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status	0.975	0.025	0.000
K63.5 Polyp of colon	0.000	0.032	0.968
Chapter VIII Diseases of the ear and mastoid process	0.966	0.034	0.000
E10 Insulin-dependent diabetes mellitus	0.966	0.034	0.000
K58 Irritable bowel syndrome	0.000	0.035	0.965
K62.5 Haemorrhage of anus and rectum	0.000	0.043	0.957
M80-M85 Disorders of bone density and structure	0.953	0.047	0.000
K58.9 Irritable bowel syndrome without diarrhoea	0.000	0.048	0.952
Chapter XII Diseases of the skin and subcutaneous tissue	0.951	0.049	0.000
Z95.8 Presence of other cardiac and vascular implants and grafts	0.948	0.052	0.000
Z86 Personal history of certain other diseases	0.947	0.053	0.000
E14 Unspecified diabetes mellitus	0.946	0.054	0.000
M31 Other necrotising vasculopathies	0.945	0.055	0.000
E10.9 Without complications	0.940	0.060	0.000
Z95.0 Presence of cardiac pacemaker	0.934	0.066	0.000
K50 Crohn's disease [regional enteritis]	0.000	0.075	0.925
E14.9 Without complications	0.925	0.075	0.000
S80-S89 Injuries to the knee and lower leg	0.923	0.077	0.000
K62.0 Anal polyp	0.000	0.079	0.921
M65-M68 Disorders of synovium and tendon	0.918	0.082	0.000
L60-L75 Disorders of skin appendages	0.918	0.082	0.000
K62.8 Other specified diseases of anus and rectum	0.000	0.084	0.916
K63.9 Disease of intestine, unspecified	0.000	0.084	0.916
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.914	0.086	0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.908	0.092	0.000
Z86.6 Personal history of diseases of the nervous system and sense organs	0.907	0.093	0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.907	0.093	0.000
M81 Osteoporosis without pathological fracture	0.903	0.097	0.000
Z86.1 Personal history of infectious and parasitic diseases	0.902	0.098	0.000
K60 Fissure and fistula of anal and rectal regions	0.000	0.100	0.900
Z95.2 Presence of prosthetic heart valve	0.896	0.104	0.000
Z86.7 Personal history of diseases of the circulatory system	0.895	0.105	0.000
K51.2 Ulcerative (chronic) proctitis	0.000	0.110	0.890
M31.6 Other giant cell arteritis	0.887	0.113	0.000
L80-L99 Other disorders of the skin and subcutaneous tissue	0.887	0.113	0.000
J33.8 Other polyp of sinus	0.884	0.116	0.000
J32 Chronic sinusitis	0.878	0.122	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.872	0.128	0.000
M81.9 Osteoporosis, unspecified	0.860	0.140	0.000
H90-H95 Other disorders of ear	0.858	0.142	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.854	0.146	0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified	0.852	0.148	0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.843	0.157	0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.841	0.159	0.000
M65 Synovitis and tenosynovitis	0.841	0.159	0.000
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified	0.838	0.162	0.000
L72 Follicular cysts of skin and subcutaneous tissue	0.836	0.164	0.000
H60-H62 Diseases of external ear	0.834	0.166	0.000
E07 Other disorders of thyroid	0.832	0.167	0.000
S70-S79 Injuries to the hip and thigh	0.832	0.168	0.000
Chapter XV Pregnancy, childbirth and the puerperium	0.830	0.170	0.000
Chapter XX External causes of morbidity and mortality	0.829	0.171	0.000
H65-H75 Diseases of middle ear and mastoid	0.828	0.172	0.000
K51.8 Other ulcerative colitis	0.000	0.173	0.827
K50.9 Crohn's disease, unspecified	0.000	0.175	0.825
L60 Nail disorders	0.824	0.176	0.000
S82 Fracture of lower leg, including ankle	0.824	0.176	0.000
S81 Open wound of lower leg	0.820	0.180	0.000
K60.3 Anal fistula	0.000	0.180	0.820
Z99.1 Dependence on respirator	0.813	0.187	0.000
Z95.4 Presence of other heart-valve replacement	0.813	0.187	0.000
L72.0 Epidermal cyst	0.809	0.191	0.000
E10.5 With peripheral circulatory complications	0.809	0.191	0.000
M21 Other acquired deformities of limbs	0.808	0.192	0.000
Z97 Presence of other devices	0.807	0.193	0.000
Z95.1 Presence of aortocoronary bypass graft	0.806	0.194	0.000
L98.8 Other specified disorders of skin and subcutaneous tissue	0.805	0.195	0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases	0.805	0.195	0.000
J45.0 Predominantly allergic asthma	0.801	0.199	0.000
K51.3 Ulcerative (chronic) rectosigmoiditis	0.000	0.201	0.799
M65.9 Synovitis and tenosynovitis, unspecified	0.797	0.203	0.000
Z92 Personal history of medical treatment	0.797	0.203	0.000
Z95.5 Presence of coronary angioplasty implant and graft	0.797	0.203	0.000
K63.3 Ulcer of intestine	0.000	0.203	0.797
E50-E64 Other nutritional deficiencies	0.796	0.204	0.000
E06 Thyroiditis	0.795	0.204	0.000
Z86.5 Personal history of other mental and behavioural disorders	0.795	0.205	0.000
K60.2 Anal fissure, unspecified	0.000	0.207	0.793
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.788	0.212	0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction	0.788	0.212	0.000
M30 Polyarteritis nodosa and related conditions	0.787	0.213	0.000
S50-S59 Injuries to the elbow and forearm	0.787	0.213	0.000
M24 Other specific joint derangements	0.786	0.214	0.000
W00-W19 Falls	0.781	0.219	0.000
M60-M63 Disorders of muscles	0.780	0.220	0.000
K62.1 Rectal polyp	0.000	0.220	0.780
E03.8 Other specified hypothyroidism	0.777	0.223	0.000
Z92.1 Personal history of long-term (current) use of anticoagulants	0.775	0.225	0.000
Z95.3 Presence of xenogenic heart valve	0.773	0.227	0.000
K50.1 Crohn's disease of large intestine	0.000	0.229	0.771
Z84 Family history of other conditions	0.771	0.229	0.000
S00-S09 Injuries to the head	0.771	0.229	0.000
E20-E35 Disorders of other endocrine glands	0.771	0.229	0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica	0.767	0.233	0.000
Z96 Presence of other functional implants	0.767	0.233	0.000
J32.9 Chronic sinusitis, unspecified	0.766	0.234	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.765	0.235	0.000
M86-M90 Other osteopathies	0.764	0.236	0.000
S90-S99 Injuries to the ankle and foot	0.764	0.236	0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.760	0.240	0.000
J34 Other disorders of nose and nasal sinuses	0.756	0.244	0.000
E10.1 With ketoacidosis	0.756	0.244	0.000
M81.90 Osteoporosis, unspecified (Multiple sites)	0.751	0.249	0.000
J35 Chronic diseases of tonsils and adenoids	0.750	0.250	0.000
K52 Other non-infective gastro-enteritis and colitis	0.000	0.252	0.748
M84 Disorders of continuity of bone	0.746	0.254	0.000
E05 Thyrotoxicosis [hyperthyroidism]	0.745	0.255	0.000
H91 Other hearing loss	0.744	0.256	0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.740	0.260	0.000
Chapter II Neoplasms	0.739	0.261	0.000
K50.0 Crohn's disease of small intestine	0.000	0.263	0.737
K90.9 Intestinal malabsorption, unspecified	0.000	0.264	0.736
M81.99 Osteoporosis, unspecified (Site unspecified)	0.734	0.266	0.000
K35-K38 Diseases of appendix	0.000	0.266	0.734
M91-M94 Chondropathies	0.730	0.270	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.730	0.270	0.000
M81.98 Osteoporosis, unspecified (Other)	0.727	0.272	0.000
Z89 Acquired absence of limb	0.727	0.273	0.000
M00-M03 Infectious arthropathies	0.726	0.273	0.000
L71 Rosacea	0.724	0.276	0.000
S89 Other and unspecified injuries of lower leg	0.724	0.276	0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.724	0.276	0.000
J44 Other chronic obstructive pulmonary disease	0.722	0.278	0.000
K62.6 Ulcer of anus and rectum	0.000	0.278	0.722
K00-K14 Diseases of oral cavity, salivary glands and jaws	0.000	0.279	0.721
H80-H83 Diseases of inner ear	0.719	0.281	0.000
M67 Other disorders of synovium and tendon	0.719	0.281	0.000
T91 Sequelae of injuries of neck and trunk	0.719	0.281	0.000
J39 Other diseases of upper respiratory tract	0.718	0.282	0.000
M06.98 Rheumatoid arthritis, unspecified (Other)	0.717	0.283	0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.717	0.283	0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.717	0.283	0.000
J33.1 Polypoid sinus degeneration	0.717	0.283	0.000
M14 Arthropathies in other diseases classified elsewhere	0.717	0.283	0.000
M12 Other specific arthropathies	0.717	0.283	0.000
M09 Juvenile arthritis in diseases classified elsewhere	0.717	0.283	0.000
M08 Juvenile arthritis	0.717	0.283	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283	0.000
M06.8 Other specified rheumatoid arthritis	0.717	0.283	0.000
M06.4 Inflammatory polyarthropathy	0.717	0.283	0.000
M06.3 Rheumatoid nodule	0.717	0.283	0.000
M06.2 Rheumatoid bursitis	0.717	0.283	0.000
M06.1 Adult-onset Still's disease	0.717	0.283	0.000
J37 Chronic laryngitis and laryngotracheitis	0.717	0.283	0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.717	0.283	0.000
M33 Dermatopolymyositis	0.717	0.283	0.000
M32 Systemic lupus erythematosus	0.717	0.283	0.000
M35.9 Systemic involvement of connective tissue, unspecified	0.717	0.283	0.000
M35.8 Other specified systemic involvement of connective tissue	0.717	0.283	0.000
M35.7 Hypermobility syndrome	0.717	0.283	0.000
M35.6 Relapsing panniculitis [Weber-Christian]	0.717	0.283	0.000
M35.5 Multifocal fibrosclerosis	0.717	0.283	0.000
M35.4 Diffuse (eosinophilic) fasciitis	0.717	0.283	0.000
M35.2 Behcet's disease	0.717	0.283	0.000
M35.1 Other overlap syndromes	0.717	0.283	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.716	0.284	0.000
E00 Congenital iodine-deficiency syndrome	0.716	0.284	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.716	0.284	0.000
E03.5 Myxoedema coma	0.716	0.284	0.000
E03.4 Atrophy of thyroid (acquired)	0.716	0.284	0.000
E03.3 Postinfectious hypothyroidism	0.716	0.284	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.716	0.284	0.000
E03.1 Congenital hypothyroidism without goitre	0.716	0.284	0.000
E03.0 Congenital hypothyroidism with diffuse goitre	0.716	0.284	0.000
C15-C26 Malignant neoplasms of digestive organs	0.716	0.284	0.000
K51.5 Mucosal proctocolitis	0.000	0.284	0.716
K51.4 Pseudopolyposis of colon	0.000	0.284	0.716
K51.1 Ulcerative (chronic) ileocolitis	0.000	0.284	0.716
K51.0 Ulcerative (chronic) enterocolitis	0.000	0.284	0.716
K64 Haemorrhoids and perianal venous thrombosis	0.000	0.285	0.715
L91 Hypertrophic disorders of skin	0.715	0.285	0.000
J40 Bronchitis, not specified as acute or chronic	0.714	0.285	0.000
J41 Simple and mucopurulent chronic bronchitis	0.714	0.286	0.000
J45.8 Mixed asthma	0.714	0.286	0.000
J45.1 Nonallergic asthma	0.714	0.286	0.000
M05.8 Other seropositive rheumatoid arthritis	0.713	0.287	0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.713	0.287	0.000
M05.2 Rheumatoid vasculitis	0.713	0.287	0.000
M05.1 Rheumatoid lung disease	0.713	0.287	0.000
M05.0 Felty's syndrome	0.713	0.287	0.000
S81.8 Open wound of other parts of lower leg	0.713	0.287	0.000
E07.9 Disorder of thyroid, unspecified	0.713	0.287	0.000
K93 Disorders of other digestive organs in diseases classified elsewhere	0.000	0.287	0.713
T79-T79 Certain early complications of trauma	0.713	0.287	0.000
T15-T19 Effects of foreign body entering through natural orifice	0.712	0.288	0.000
K90.8 Other intestinal malabsorption	0.000	0.288	0.712
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.000	0.288	0.712
K90.3 Pancreatic steatorrhoea	0.000	0.288	0.712
K90.2 Blind loop syndrome, not elsewhere classified	0.000	0.288	0.712
K90.1 Tropical sprue	0.000	0.288	0.712
J20-J22 Other acute lower respiratory infections	0.712	0.288	0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.711	0.289	0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.710	0.289	0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.710	0.289	0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.710	0.289	0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.710	0.289	0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.710	0.289	0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.710	0.289	0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.710	0.289	0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.710	0.289	0.000
K62.2 Anal prolapse	0.000	0.290	0.710
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.709	0.291	0.000
E12 Malnutrition-related diabetes mellitus	0.709	0.291	0.000
Z97.5 Presence of (intra-uterine) contraceptive device	0.707	0.293	0.000
H69 Other disorders of Eustachian tube	0.706	0.294	0.000
T98 Sequelae of other and unspecified effects of external causes	0.706	0.294	0.000
T51 Toxic effect of alcohol	0.706	0.294	0.000
Chapter VII Diseases of the eye and adnexa	0.705	0.295	0.000
K63.4 Enteroptosis	0.000	0.296	0.704
K63.0 Abscess of intestine	0.000	0.296	0.704
T33-T35 Frostbite	0.702	0.298	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.702	0.298	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.702	0.298	0.000
T00-T07 Injuries involving multiple body regions	0.702	0.298	0.000
M34 Systemic sclerosis	0.702	0.298	0.000
S10-S19 Injuries to the neck	0.700	0.299	0.000
M85 Other disorders of bone density and structure	0.699	0.300	0.000
Z81 Family history of mental and behavioural disorders	0.699	0.301	0.000
S82.8 Fractures of other parts of lower leg	0.699	0.301	0.000
M80 Osteoporosis with pathological fracture	0.699	0.301	0.000
L20-L30 Dermatitis and eczema	0.698	0.301	0.000
E13 Other specified diabetes mellitus	0.698	0.302	0.000
Z36 Antenatal screening	0.698	0.302	0.000
Z35 Supervision of high-risk pregnancy	0.698	0.302	0.000
Chapter XXII Codes for special purposes	0.697	0.303	0.000
Z96.1 Presence of intraocular lens	0.697	0.303	0.000
W07 Fall involving chair	0.696	0.304	0.000
Z29 Need for other prophylactic measures	0.696	0.304	0.000
L89 Decubitus ulcer	0.694	0.306	0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis	0.694	0.306	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.694	0.306	0.000
E10.8 With unspecified complications	0.693	0.307	0.000
E10.7 With multiple complications	0.693	0.307	0.000
E10.6 With other specified complications	0.693	0.307	0.000
E10.2 With renal complications	0.693	0.307	0.000
E10.0 With coma	0.693	0.307	0.000
L60.0 Ingrowing nail	0.691	0.309	0.000
K62.4 Stenosis of anus and rectum	0.000	0.309	0.690
M81.4 Drug-induced osteoporosis	0.689	0.311	0.000
L50-L54 Urticaria and erythema	0.688	0.312	0.000
H61 Other disorders of external ear	0.688	0.312	0.000
M65.91 Synovitis and tenosynovitis, unspecified (Shoulder region)	0.687	0.313	0.000
L90 Atrophic disorders of skin	0.687	0.313	0.000
V20-V29 Motorcycle rider injured in transport accident	0.685	0.315	0.000
M83 Adult osteomalacia	0.683	0.317	0.000
M82 Osteoporosis in diseases classified elsewhere	0.683	0.317	0.000
C19 Malignant neoplasm of rectosigmoid junction	0.682	0.318	0.000
L10-L14 Bullous disorders	0.681	0.318	0.000
K65-K67 Diseases of peritoneum	0.000	0.319	0.681
H60 Otitis externa	0.681	0.319	0.000
J32.0 Chronic maxillary sinusitis	0.679	0.321	0.000
S20-S29 Injuries to the thorax	0.678	0.322	0.000
J42 Unspecified chronic bronchitis	0.678	0.322	0.000
M11 Other crystal arthropathies	0.678	0.322	0.000
E14.8 With unspecified complications	0.678	0.322	0.000
E14.7 With multiple complications	0.678	0.322	0.000
E14.6 With other specified complications	0.678	0.322	0.000
E14.5 With peripheral circulatory complications	0.678	0.322	0.000
E14.4 With neurological complications	0.678	0.322	0.000
E14.2 Withrenal complications	0.678	0.322	0.000
E14.1 With ketoacidosis	0.678	0.322	0.000
E14.0 With coma	0.678	0.322	0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.678	0.322	0.000
M31.9 Necrotising vasculopathy, unspecified	0.678	0.322	0.000
M31.8 Other specified necrotising vasculopathies	0.678	0.322	0.000
M31.7 Microscopic polyangiitis	0.678	0.322	0.000
M31.4 Aortic arch syndrome [Takayasu]	0.678	0.322	0.000
M31.2 Lethal midline granuloma	0.678	0.322	0.000
M31.1 Thrombotic microangiopathy	0.678	0.322	0.000
M31.0 Hypersensitivity angiitis	0.678	0.322	0.000
Q50-Q56 Congenital malformations of genital organs	0.678	0.322	0.000
S60-S69 Injuries to the wrist and hand	0.676	0.324	0.000
Chapter V Mental and behavioural disorders	0.676	0.324	0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified	0.676	0.324	0.000
M31.3 Wegener's granulomatosis	0.676	0.324	0.000
E40-E46 Malnutrition	0.675	0.324	0.000
Z92.8 Personal history of other medical treatment	0.676	0.324	0.000
W10 Fall on and from stairs and steps	0.675	0.325	0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.675	0.325	0.000
H74 Other disorders of middle ear and mastoid	0.674	0.326	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.674	0.326	0.000
J34.2 Deviated nasal septum	0.674	0.326	0.000
E27 Other disorders of adrenal gland	0.673	0.327	0.000
T56 Toxic effect of metals	0.673	0.327	0.000
O85-O92 Complications predominantly related to the puerperium	0.672	0.328	0.000
L92 Granulomatous disorders of skin and subcutaneous tissue	0.671	0.329	0.000
K92 Other diseases of digestive system	0.000	0.331	0.669
T66-T78 Other and unspecified effects of external causes	0.668	0.332	0.000
H93 Other disorders of ear, not elsewhere classified	0.667	0.332	0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.667	0.333	0.000
L72.9 Follicular cyst of skin and subcutaneous tissue, unspecified	0.667	0.333	0.000
Z92.0 Personal history of contraception	0.666	0.334	0.000
L97 Ulcer of lower limb, not elsewhere classified	0.664	0.336	0.000
H92 Otalgia and effusion of ear	0.664	0.336	0.000
S70 Superficial injury of hip and thigh	0.663	0.337	0.000
S81.9 Open wound of lower leg, part unspecified	0.663	0.337	0.000
H91.9 Hearing loss, unspecified	0.663	0.337	0.000
L60.2 Onychogryphosis	0.663	0.337	0.000
J46 Status asthmaticus	0.662	0.338	0.000
S88 Traumatic amputation of lower leg	0.661	0.338	0.000
S87 Crushing injury of lower leg	0.661	0.338	0.000
S86 Injury of muscle and tendon at lower leg level	0.661	0.338	0.000
S85 Injury of blood vessels at lower leg level	0.661	0.338	0.000
S84 Injury of nerves at lower leg level	0.661	0.338	0.000
K02 Dental caries	0.000	0.339	0.661
Z80 Family history of malignant neoplasm	0.660	0.340	0.000
Q80-Q89 Other congenital malformations	0.660	0.340	0.000
M06.0 Seronegative rheumatoid arthritis	0.659	0.341	0.000
L98.9 Disorder of skin and subcutaneous tissue, unspecified	0.658	0.342	0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere	0.658	0.342	0.000
M66 Spontaneous rupture of synovium and tendon	0.658	0.342	0.000
L75 Apocrine sweat disorders	0.658	0.342	0.000
L74 Eccrine sweat disorders	0.658	0.342	0.000
L70 Acne	0.658	0.342	0.000
L68 Hypertrichosis	0.658	0.342	0.000
L67 Hair colour and hair shaft abnormalities	0.658	0.342	0.000
L66 Cicatricial alopecia [scarring hair loss]	0.658	0.342	0.000
L65 Other nonscarring hair loss	0.658	0.342	0.000
L64 Androgenic alopecia	0.658	0.342	0.000
L63 Alopecia areata	0.658	0.342	0.000
L62 Nail disorders in diseases classified elsewhere	0.658	0.342	0.000
Q60-Q64 Congenital malformations of the urinary system	0.657	0.343	0.000
M07 Psoriatic and enteropathic arthropathies	0.655	0.345	0.000
L60.8 Other nail disorders	0.654	0.346	0.000
S82.4 Fracture of fibula alone	0.653	0.347	0.000
M21.0 Valgus deformity, not elsewhere classified	0.653	0.347	0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.652	0.348	0.000
E53 Deficiency of other B group vitamins	0.652	0.348	0.000
S00 Superficial injury of head	0.652	0.348	0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances	0.651	0.349	0.000
E06.3 Autoimmune thyroiditis	0.649	0.350	0.000
Z33 Pregnant state, incidental	0.649	0.351	0.000
V10-V19 Pedal cyclist injured in transport accident	0.649	0.351	0.000
E10.4 With neurological complications	0.648	0.351	0.000
S82.5 Fracture of medial malleolus	0.648	0.352	0.000
D37-D48 Neoplasms of uncertain or unknown behaviour	0.648	0.352	0.000
M65.97 Synovitis and tenosynovitis, unspecified (Ankle and foot)	0.648	0.352	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.647	0.353	0.000
M81.8 Other osteoporosis	0.647	0.353	0.000
M81.6 Localised osteoporosis [Lequesne]	0.647	0.353	0.000
M81.5 Idiopathic osteoporosis	0.647	0.353	0.000
M81.3 Postsurgical malabsorption osteoporosis	0.647	0.353	0.000
M81.2 Osteoporosis of disuse	0.647	0.353	0.000
M81.1 Postoophorectomy osteoporosis	0.647	0.353	0.000
M81.0 Postmenopausal osteoporosis	0.647	0.353	0.000
M13 Other arthritis	0.647	0.353	0.000
K60.5 Anorectal fistula	0.000	0.354	0.645
K60.4 Rectal fistula	0.000	0.354	0.645
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.645	0.355	0.000
K14 Diseases of tongue	0.000	0.357	0.643
S71 Open wound of hip and thigh	0.643	0.357	0.000
M65.96 Synovitis and tenosynovitis, unspecified (Lower leg)	0.643	0.357	0.000
O47 False labour	0.642	0.358	0.000
E10.3 With ophthalmic complications	0.640	0.360	0.000
J32.4 Chronic pansinusitis	0.639	0.361	0.000
M65.93 Synovitis and tenosynovitis, unspecified (Forearm)	0.638	0.362	0.000
H53-H54 Visual disturbances and blindness	0.638	0.362	0.000
M24.5 Contracture of joint	0.636	0.363	0.000
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere	0.636	0.364	0.000
L95 Vasculitis limited to skin, not elsewhere classified	0.636	0.364	0.000
L94 Other localised connective tissue disorders	0.636	0.364	0.000
L93 Lupus erythematosus	0.636	0.364	0.000
L87 Transepidermal elimination disorders	0.636	0.364	0.000
L88 Pyoderma gangrenosum	0.636	0.364	0.000
L86 Keratoderma in diseases classified elsewhere	0.636	0.364	0.000
L83 Acanthosis nigricans	0.636	0.364	0.000
L80 Vitiligo	0.636	0.364	0.000
L73 Other follicular disorders	0.636	0.364	0.000
M30.1 Polyarteritis with lung involvement [Churg-Strauss]	0.635	0.365	0.000
S51 Open wound of forearm	0.635	0.365	0.000
K59 Other functional intestinal disorders	0.000	0.365	0.635
C73 Malignant neoplasm of thyroid gland	0.635	0.365	0.000
K52.8 Other specified non-infective gastro-enteritis and colitis	0.000	0.366	0.634
K62.3 Rectal prolapse	0.000	0.367	0.633
T90 Sequelae of injuries of head	0.632	0.368	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.632	0.368	0.000
S72 Fracture of femur	0.630	0.370	0.000
J32.8 Other chronic sinusitis	0.630	0.370	0.000
J32.3 Chronic sphenoidal sinusitis	0.630	0.370	0.000
J32.1 Chronic frontal sinusitis	0.630	0.370	0.000
W13 Fall from, out of or through building or structure	0.629	0.371	0.000
J32.2 Chronic ethmoidal sinusitis	0.629	0.371	0.000
H66 Suppurative and unspecified otitis media	0.626	0.374	0.000
X60-X84 Intentional self-harm	0.626	0.374	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.625	0.374	0.000
Q35-Q37 Cleft lip and cleft palate	0.625	0.374	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.625	0.374	0.000
K02.9 Dental caries, unspecified	0.000	0.375	0.625
Z84.8 Family history of other specified conditions	0.624	0.376	0.000
K62.7 Radiation proctitis	0.000	0.376	0.624
M22 Disorders of patella	0.623	0.377	0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue	0.623	0.377	0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.623	0.377	0.000
M62 Other disorders of muscle	0.623	0.377	0.000
K63.1 Perforation of intestine (nontraumatic)	0.000	0.377	0.622
T51.0 Ethanol	0.622	0.378	0.000
S82.6 Fracture of lateral malleolus	0.620	0.380	0.000
Z91 Personal history of risk-factors, not elsewhere classified	0.619	0.381	0.000
W07.0 Home	0.619	0.381	0.000
S79 Other and unspecified injuries of hip and thigh	0.618	0.381	0.000
H69.9 Eustachian tube disorder, unspecified	0.618	0.382	0.000
Z36.9 Antenatal screening, unspecified	0.617	0.383	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.617	0.383	0.000
M81.97 Osteoporosis, unspecified (Ankle and foot)	0.617	0.383	0.000
M81.96 Osteoporosis, unspecified (Lower leg)	0.617	0.383	0.000
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)	0.617	0.383	0.000
M81.94 Osteoporosis, unspecified (Hand)	0.617	0.383	0.000
M81.93 Osteoporosis, unspecified (Forearm)	0.617	0.383	0.000
M81.92 Osteoporosis, unspecified (Upper arm)	0.617	0.383	0.000
M81.91 Osteoporosis, unspecified (Shoulder region)	0.617	0.383	0.000
S82.1 Fracture of upper end of tibia	0.616	0.384	0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified	0.615	0.385	0.000
H94 Other disorders of ear in diseases classified elsewhere	0.615	0.385	0.000
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot	0.615	0.385	0.000
S82.0 Fracture of patella	0.614	0.386	0.000
E55 Vitamin D deficiency	0.614	0.386	0.000
T95 Sequelae of burns, corrosions and frostbite	0.612	0.388	0.000
T94 Sequelae of injuries involving multiple and unspecified body regions	0.612	0.388	0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.612	0.388	0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.612	0.388	0.000
C20 Malignant neoplasm of rectum	0.611	0.389	0.000
O80-O84 Delivery	0.611	0.389	0.000
C21 Malignant neoplasm of anus and anal canal	0.611	0.389	0.000
T92 Sequelae of injuries of upper limb	0.611	0.389	0.000
Z99.9 Dependence on unspecified enabling machine and device	0.611	0.389	0.000
Z99.4 Dependence on artificial heart	0.611	0.389	0.000
Z99.0 Dependence on aspirator	0.611	0.389	0.000
T14 Injury of unspecified body region	0.611	0.389	0.000
S82.80 Fractures of other parts of lower leg (closed)	0.610	0.390	0.000
L30 Other dermatitis	0.608	0.392	0.000
Q00-Q07 Congenital malformations of the nervous system	0.607	0.392	0.000
H52 Disorders of refraction and accommodation	0.607	0.393	0.000
J00-J06 Acute upper respiratory infections	0.607	0.393	0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension	0.607	0.393	0.000
M21.3 Wrist or foot drop (acquired)	0.607	0.393	0.000
M24.0 Loose body in joint	0.607	0.393	0.000
S52 Fracture of forearm	0.607	0.393	0.000
Z99.2 Dependence on renal dialysis	0.607	0.393	0.000
L84 Corns and callosities	0.606	0.394	0.000
K50.8 Other Crohn's disease	0.000	0.395	0.605
W06 Fall involving bed	0.605	0.395	0.000
T65 Toxic effect of other and unspecified substances	0.604	0.396	0.000
T63 Toxic effect of contact with venomous animals	0.604	0.396	0.000
T62 Toxic effect of other noxious substances eaten as food	0.604	0.396	0.000
T61 Toxic effect of noxious substances eaten as seafood	0.604	0.396	0.000
T60 Toxic effect of pesticides	0.604	0.396	0.000
T59 Toxic effect of other gases, fumes and vapours	0.604	0.396	0.000
T57 Toxic effect of other inorganic substances	0.604	0.396	0.000
T54 Toxic effect of corrosive substances	0.604	0.396	0.000
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone	0.604	0.396	0.000
T52 Toxic effect of organic solvents	0.604	0.396	0.000
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants	0.604	0.396	0.000
T58 Toxic effect of carbon monoxide	0.604	0.396	0.000
T55 Toxic effect of soaps and detergents	0.604	0.396	0.000
L90.0 Lichen sclerosus et atrophicus	0.604	0.396	0.000
J44.9 Chronic obstructive pulmonary disease, unspecified	0.603	0.397	0.000
M65.8 Other synovitis and tenosynovitis	0.603	0.397	0.000
M65.2 Calcific tendinitis	0.603	0.397	0.000
M65.1 Other infective (teno)synovitis	0.603	0.397	0.000
M65.0 Abscess of tendon sheath	0.603	0.397	0.000
L98.7 Excessive and redundant skin and subcutaneous tissue	0.601	0.399	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations