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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs116375727
log Bayes Factor = 13.6047
Chromosome 2   position 2,807,724  (GRCh37) Explore rs116375727 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XIV Diseases of the genitourinary system
1.000 0.000 0.000
Chapter VIII Diseases of the ear and mastoid process
0.999 0.001 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.999 0.001 0.000
N40-N51 Diseases of male genital organs
0.998 0.002 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.997 0.003 0.000
N40 Hyperplasia of prostate
0.996 0.004 0.000
H65-H75 Diseases of middle ear and mastoid
0.990 0.010 0.000
Chapter X Diseases of the respiratory system
0.990 0.010 0.000
Chapter VI Diseases of the nervous system
0.984 0.016 0.000
G40-G47 Episodic and paroxysmal disorders
0.981 0.019 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.973 0.027 0.000
G47 Sleep disorders
0.968 0.032 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.967 0.033 0.000
N17-N19 Renal failure
0.967 0.033 0.000
H90-H95 Other disorders of ear
0.963 0.037 0.000
Chapter VII Diseases of the eye and adnexa
0.962 0.038 0.000
N10-N16 Renal tubulo-interstitial diseases
0.957 0.043 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.951 0.049 0.000
G47.3 Sleep apnoea
0.950 0.050 0.000
N50 Other disorders of male genital organs
0.948 0.052 0.000
H65 Nonsuppurative otitis media
0.945 0.055 0.000
E10-E14 Diabetes mellitus
0.934 0.066 0.000
H90 Conductive and sensorineural hearing loss
0.931 0.069 0.000
J09-J18 Influenza and pneumonia
0.930 0.070 0.000
S60-S69 Injuries to the wrist and hand
0.930 0.070 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.929 0.071 0.000
J95-J99 Other diseases of the respiratory system
0.920 0.080 0.000
N19 Unspecified renal failure
0.919 0.081 0.000
H25-H28 Disorders of lens
0.919 0.081 0.000
Chapter XX External causes of morbidity and mortality
0.913 0.087 0.000
H65.3 Chronic mucoid otitis media
0.905 0.095 0.000
N50.8 Other specified disorders of male genital organs
0.903 0.097 0.000
H72 Perforation of tympanic membrane
0.902 0.098 0.000
T81 Complications of procedures, not elsewhere classified
0.896 0.104 0.000
M05-M14 Inflammatory polyarthropathies
0.895 0.105 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.895 0.105 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.893 0.107 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.891 0.109 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.888 0.112 0.000
H60-H62 Diseases of external ear
0.886 0.114 0.000
R30-R39 Symptoms and signs involving the urinary system
0.884 0.116 0.000
M50-M54 Other dorsopathies
0.883 0.117 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.883 0.117 0.000
E11 Non-insulin-dependent diabetes mellitus
0.880 0.120 0.000
N18 Chronic renal failure
0.879 0.121 0.000
J30-J39 Other diseases of upper respiratory tract
0.877 0.123 0.000
M80-M85 Disorders of bone density and structure
0.876 0.124 0.000
N13 Obstructive and reflux uropathy
0.873 0.127 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.871 0.129 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.870 0.130 0.000
H25 Senile cataract
0.865 0.135 0.000
H02 Other disorders of eyelid
0.864 0.136 0.000
J40-J47 Chronic lower respiratory diseases
0.862 0.138 0.000
N00-N08 Glomerular diseases
0.861 0.139 0.000
H25.0 Senile incipient cataract
0.855 0.145 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.851 0.149 0.000
J18 Pneumonia, organism unspecified
0.850 0.150 0.000
J98 Other respiratory disorders
0.849 0.151 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.848 0.152 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.848 0.152 0.000
G43 Migraine
0.842 0.158 0.000
G40 Epilepsy
0.841 0.159 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.841 0.159 0.000
H02.8 Other specified disorders of eyelid
0.838 0.162 0.000
E16 Other disorders of pancreatic internal secretion
0.835 0.165 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.831 0.169 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.830 0.170 0.000
S50-S59 Injuries to the elbow and forearm
0.826 0.174 0.000
G47.9 Sleep disorder, unspecified
0.824 0.176 0.000
S40-S49 Injuries to the shoulder and upper arm
0.823 0.177 0.000
S64 Injury of nerves at wrist and hand level
0.822 0.178 0.000
Chapter XXII Codes for special purposes
0.820 0.180 0.000
M13 Other arthritis
0.819 0.181 0.000
S90-S99 Injuries to the ankle and foot
0.818 0.182 0.000
H90.5 Sensorineural hearing loss, unspecified
0.816 0.184 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.815 0.185 0.000
H61 Other disorders of external ear
0.812 0.187 0.000
J98.4 Other disorders of lung
0.806 0.194 0.000
J18.1 Lobar pneumonia, unspecified
0.805 0.195 0.000
J33 Nasal polyp
0.804 0.196 0.000
R50-R69 General symptoms and signs
0.804 0.196 0.000
S20-S29 Injuries to the thorax
0.804 0.196 0.000
R18 Ascites
0.802 0.198 0.000
R40 Somnolence, stupor and coma
0.799 0.201 0.000
H69 Other disorders of Eustachian tube
0.798 0.201 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.797 0.203 0.000
R63 Symptoms and signs concerning food and fluid intake
0.796 0.204 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.795 0.205 0.000
M54 Dorsalgia
0.794 0.206 0.000
E16.2 Hypoglycaemia, unspecified
0.793 0.207 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.793 0.207 0.000
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified
0.792 0.208 0.000
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified
0.792 0.208 0.000
Q60-Q64 Congenital malformations of the urinary system
0.790 0.210 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.790 0.210 0.000
T79-T79 Certain early complications of trauma
0.789 0.211 0.000
S80-S89 Injuries to the knee and lower leg
0.788 0.212 0.000
H80-H83 Diseases of inner ear
0.787 0.213 0.000
H66 Suppurative and unspecified otitis media
0.785 0.215 0.000
E20-E35 Disorders of other endocrine glands
0.784 0.216 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.779 0.221 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.779 0.221 0.000
R23 Other skin changes
0.778 0.222 0.000
E11.3 With ophthalmic complications
0.778 0.222 0.000
S70-S79 Injuries to the hip and thigh
0.778 0.222 0.000
J33.9 Nasal polyp, unspecified
0.777 0.223 0.000
H90.2 Conductive hearing loss, unspecified
0.777 0.223 0.000
M51 Other intervertebral disk disorders
0.776 0.224 0.000
H90.3 Sensorineural hearing loss, bilateral
0.776 0.224 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.776 0.224 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.775 0.225 0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction
0.775 0.225 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.773 0.227 0.000
J32 Chronic sinusitis
0.771 0.229 0.000
G44 Other headache syndromes
0.769 0.231 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.769 0.231 0.000
Chapter II Neoplasms
0.768 0.232 0.000
G41 Status epilepticus
0.767 0.232 0.000
N25-N29 Other disorders of kidney and ureter
0.766 0.234 0.000
E10 Insulin-dependent diabetes mellitus
0.766 0.234 0.000
M13.9 Arthritis, unspecified
0.765 0.235 0.000
H27 Other disorders of lens
0.764 0.236 0.000
M86-M90 Other osteopathies
0.764 0.236 0.000
R32 Unspecified urinary incontinence
0.764 0.236 0.000
T81.8 Other complications of procedures, not elsewhere classified
0.763 0.237 0.000
M85 Other disorders of bone density and structure
0.761 0.239 0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes
0.761 0.239 0.000
M84 Disorders of continuity of bone
0.761 0.239 0.000
N18.0 End-stage renal disease
0.760 0.240 0.000
R63.0 Anorexia
0.760 0.240 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.759 0.241 0.000
G70-G73 Diseases of myoneural junction and muscle
0.758 0.242 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.758 0.242 0.000
M13.99 Arthritis, unspecified (Site unspecified)
0.758 0.242 0.000
H91 Other hearing loss
0.757 0.243 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.756 0.244 0.000
R63.4 Abnormal weight loss
0.755 0.245 0.000
H72.9 Perforation of tympanic membrane, unspecified
0.752 0.248 0.000
M91-M94 Chondropathies
0.751 0.248 0.000
M60-M63 Disorders of muscles
0.751 0.249 0.000
J60-J70 Lung diseases due to external agents
0.751 0.249 0.000
Chapter I Certain infectious and parasitic diseases
0.751 0.249 0.000
M54.9 Dorsalgia, unspecified
0.751 0.249 0.000
H90.0 Conductive hearing loss, bilateral
0.750 0.249 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.750 0.250 0.000
N18.9 Chronic renal failure, unspecified
0.749 0.251 0.000
E50-E64 Other nutritional deficiencies
0.749 0.251 0.000
S61 Open wound of wrist and hand
0.747 0.253 0.000
J47 Bronchiectasis
0.746 0.254 0.000
R14 Flatulence and related conditions
0.746 0.254 0.000
N41 Inflammatory diseases of prostate
0.744 0.255 0.000
R93.4 Abnormal findings on diagnostic imaging of urinary organs
0.743 0.257 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.742 0.258 0.000
H72.8 Other perforations of tympanic membrane
0.741 0.258 0.000
N05 Unspecified nephritic syndrome
0.741 0.259 0.000
R17 Unspecified jaundice
0.741 0.259 0.000
H71 Cholesteatoma of middle ear
0.740 0.260 0.000
N18.5 Chronic kidney disease, stage 5
0.740 0.260 0.000
J44 Other chronic obstructive pulmonary disease
0.739 0.261 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.739 0.261 0.000
N50.1 Vascular disorders of male genital organs
0.738 0.262 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.735 0.265 0.000
E11.4 With neurological complications
0.734 0.266 0.000
H65.9 Nonsuppurative otitis media, unspecified
0.734 0.266 0.000
M07 Psoriatic and enteropathic arthropathies
0.732 0.268 0.000
E11.5 With peripheral circulatory complications
0.732 0.268 0.000
R93.2 Abnormal findings on diagnostic imaging of liver and biliary tract
0.731 0.269 0.000
N47 Redundant prepuce, phimosis and paraphimosis
0.731 0.269 0.000
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.731 0.269 0.000
R44.1 Visual hallucinations
0.730 0.270 0.000
H72.0 Central perforation of tympanic membrane
0.730 0.270 0.000
Chapter IX Diseases of the circulatory system
0.729 0.271 0.000
H10-H13 Disorders of conjunctiva
0.728 0.272 0.000
R45 Symptoms and signs involving emotional state
0.728 0.272 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.727 0.273 0.000
V20-V29 Motorcycle rider injured in transport accident
0.727 0.273 0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.727 0.273 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.726 0.274 0.000
X60-X84 Intentional self-harm
0.723 0.276 0.000
R34 Anuria and oliguria
0.721 0.278 0.000
M45-M49 Spondylopathies
0.720 0.280 0.000
S51 Open wound of forearm
0.720 0.280 0.000
E14 Unspecified diabetes mellitus
0.719 0.281 0.000
S67 Crushing injury of wrist and hand
0.718 0.282 0.000
R93.3 Abnormal findings on diagnostic imaging of other parts of digestive tract
0.718 0.282 0.000
S42 Fracture of shoulder and upper arm
0.718 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
C64-C68 Malignant neoplasms of urinary tract
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
S10-S19 Injuries to the neck
0.717 0.283 0.000
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side
0.717 0.283 0.000
N13.3 Other and unspecified hydronephrosis
0.716 0.284 0.000
N51 Disorders of male genital organs in diseases classified elsewhere
0.716 0.284 0.000
N46 Male infertility
0.716 0.284 0.000
N44 Torsion of testis
0.716 0.284 0.000
Q61 Cystic kidney disease
0.716 0.284 0.000
N99-N99 Other disorders of the genitourinary system
0.715 0.284 0.000
R20 Disturbances of skin sensation
0.715 0.285 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.715 0.285 0.000
Y95 Nosocomial condition
0.714 0.286 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.714 0.286 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.712 0.288 0.000
R30 Pain associated with micturition
0.711 0.289 0.000
H61.2 Impacted cerumen
0.710 0.290 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.710 0.290 0.000
H74 Other disorders of middle ear and mastoid
0.710 0.290 0.000
H70 Mastoiditis and related conditions
0.710 0.290 0.000
H68 Eustachian salpingitis and obstruction
0.710 0.290 0.000
H67 Otitis media in diseases classified elsewhere
0.710 0.290 0.000
M00-M03 Infectious arthropathies
0.709 0.290 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.708 0.292 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.707 0.293 0.000
N72 Inflammatory disease of cervix uteri
0.707 0.293 0.000
T81.9 Unspecified complication of procedure
0.707 0.293 0.000
T81.3 Disruption of operation wound, not elsewhere classified
0.707 0.293 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.706 0.294 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.705 0.295 0.000
V40-V49 Car occupant injured in transport accident
0.705 0.295 0.000
R41.8 Other and unspecified symptoms and signs involving cognitive functions and awareness
0.705 0.295 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.705 0.295 0.000
S68 Traumatic amputation of wrist and hand
0.705 0.295 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.704 0.296 0.000
T86 Failure and rejection of transplanted organs and tissues
0.704 0.296 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.703 0.297 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.703 0.297 0.000
H92 Otalgia and effusion of ear
0.701 0.299 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.701 0.299 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.701 0.299 0.000
C15-C26 Malignant neoplasms of digestive organs
0.698 0.302 0.000
E40-E46 Malnutrition
0.698 0.302 0.000
N20-N23 Urolithiasis
0.697 0.303 0.000
M54.99 Dorsalgia, unspecified (Site unspecified)
0.697 0.303 0.000
R29.6 Tendency to fall, not elsewhere classified
0.696 0.304 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.696 0.304 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.696 0.304 0.000
R51 Headache
0.695 0.305 0.000
H61.0 Perichondritis of external ear
0.695 0.305 0.000
G47.8 Other sleep disorders
0.694 0.306 0.000
G47.4 Narcolepsy and cataplexy
0.694 0.306 0.000
G47.2 Disorders of the sleep-wake schedule
0.694 0.306 0.000
G47.1 Disorders of excessive somnolence [hypersomnias]
0.694 0.306 0.000
G47.0 Disorders of initiating and maintaining sleep [insomnias]
0.694 0.306 0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified
0.690 0.310 0.000
H94 Other disorders of ear in diseases classified elsewhere
0.690 0.310 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.689 0.311 0.000
H02.0 Entropion and trichiasis of eyelid
0.689 0.311 0.000
M11 Other crystal arthropathies
0.689 0.311 0.000
T39.1 4-Aminophenol derivatives
0.686 0.314 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.686 0.314 0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere
0.686 0.314 0.000
N15 Other renal tubulo-interstitial diseases
0.686 0.314 0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
0.686 0.314 0.000
N11 Chronic tubulo-interstitial nephritis
0.686 0.314 0.000
R44.8 Other and unspecified symptoms and signs involving general sensations and perceptions
0.684 0.316 0.000
H73 Other disorders of tympanic membrane
0.683 0.317 0.000
R46 Symptoms and signs involving appearance and behaviour
0.682 0.318 0.000
R43 Disturbances of smell and taste
0.682 0.318 0.000
R93.0 Abnormal findings on diagnostic imaging of skull and head, not elsewhere classified
0.681 0.319 0.000
G43.8 Other migraine
0.680 0.319 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.680 0.320 0.000
N50.9 Disorder of male genital organs, unspecified
0.680 0.320 0.000
N50.0 Atrophy of testis
0.680 0.320 0.000
M80 Osteoporosis with pathological fracture
0.679 0.321 0.000
L03 Cellulitis
0.679 0.321 0.000
I77 Other disorders of arteries and arterioles
0.679 0.321 0.000
G43.9 Migraine, unspecified
0.678 0.322 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.678 0.322 0.000
H65.4 Other chronic nonsuppurative otitis media
0.678 0.322 0.000
H65.2 Chronic serous otitis media
0.678 0.322 0.000
H65.1 Other acute nonsuppurative otitis media
0.678 0.322 0.000
H65.0 Acute serous otitis media
0.678 0.322 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.677 0.323 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.676 0.324 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.676 0.324 0.000
J98.8 Other specified respiratory disorders
0.675 0.325 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.675 0.325 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.675 0.325 0.000
S60 Superficial injury of wrist and hand
0.674 0.326 0.000
S64.3 Injury of digital nerve of thumb
0.672 0.328 0.000
G30-G32 Other degenerative diseases of the nervous system
0.672 0.328 0.000
Y86 Sequelae of other accidents
0.672 0.328 0.000
C67 Malignant neoplasm of bladder
0.671 0.329 0.000
S32 Fracture of lumbar spine and pelvis
0.670 0.330 0.000
R31 Unspecified haematuria
0.670 0.330 0.000
E12 Malnutrition-related diabetes mellitus
0.670 0.330 0.000
E13 Other specified diabetes mellitus
0.669 0.331 0.000
H26 Other cataract
0.668 0.332 0.000
H90.8 Mixed conductive and sensorineural hearing loss, unspecified
0.668 0.332 0.000
H90.7 Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
0.668 0.332 0.000
H90.6 Mixed conductive and sensorineural hearing loss, bilateral
0.668 0.332 0.000
H90.4 Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
0.668 0.332 0.000
N76 Other inflammation of vagina and vulva
0.668 0.332 0.000
S62 Fracture at wrist and hand level
0.667 0.333 0.000
J17 Pneumonia in diseases classified elsewhere
0.667 0.333 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.667 0.333 0.000
J12 Viral pneumonia, not elsewhere classified
0.667 0.333 0.000
J11 Influenza, virus not identified
0.667 0.333 0.000
J10 Influenza due to identified influenza virus
0.667 0.333 0.000
J14 Pneumonia due to Haemophilus influenzae
0.667 0.333 0.000
J09 Influenza due to certain identified influenza virus
0.667 0.333 0.000
H53-H54 Visual disturbances and blindness
0.667 0.333 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.667 0.333 0.000
S69 Other and unspecified injuries of wrist and hand
0.666 0.333 0.000
S65 Injury of blood vessels at wrist and hand level
0.666 0.333 0.000
J42 Unspecified chronic bronchitis
0.666 0.334 0.000
T87 Complications peculiar to reattachment and amputation
0.666 0.334 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.666 0.334 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.666 0.334 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.666 0.334 0.000
T93 Sequelae of injuries of lower limb
0.665 0.335 0.000
G20-G26 Extrapyramidal and movement disorders
0.663 0.336 0.000
R23.1 Pallor
0.663 0.337 0.000
N45 Orchitis and epididymitis
0.663 0.337 0.000
J18.9 Pneumonia, unspecified
0.663 0.337 0.000
R57 Shock, not elsewhere classified
0.663 0.337 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.663 0.337 0.000
M85.8 Other specified disorders of bone density and structure
0.662 0.338 0.000
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
0.662 0.338 0.000
E70-E90 Metabolic disorders
0.662 0.338 0.000
H69.9 Eustachian tube disorder, unspecified
0.661 0.339 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.661 0.339 0.000
R35 Polyuria
0.661 0.339 0.000
S64.2 Injury of radial nerve at wrist and hand level
0.660 0.340 0.000
E11.2 With renal complications
0.660 0.340 0.000
J99 Respiratory disorders in diseases classified elsewhere
0.660 0.340 0.000
J96 Respiratory failure, not elsewhere classified
0.660 0.340 0.000
R27 Other lack of coordination
0.660 0.340 0.000
H28 Cataract and other disorders of lens in diseases classified elsewhere
0.659 0.341 0.000
R60 Oedema, not elsewhere classified
0.657 0.343 0.000
S50 Superficial injury of forearm
0.657 0.343 0.000
M53 Other dorsopathies, not elsewhere classified
0.656 0.344 0.000
E10.4 With neurological complications
0.656 0.344 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.655 0.345 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.655 0.345 0.000
Y35-Y36 Legal intervention and operations of war
0.655 0.345 0.000
Y10-Y34 Event of undetermined intent
0.655 0.345 0.000
Y00-Y09 Assault
0.655 0.345 0.000
X85-X99 Assault
0.655 0.345 0.000
X50-X57 Overexertion, travel and privation
0.655 0.345 0.000
X30-X39 Exposure to forces of nature
0.655 0.345 0.000
X20-X29 Contact with venomous animals and plants
0.655 0.345 0.000
X10-X19 Contact with heat and hot substances
0.655 0.345 0.000
X00-X09 Exposure to smoke, fire and flames
0.655 0.345 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.655 0.345 0.000
W75-W84 Other accidental threats to breathing
0.655 0.345 0.000
W65-W74 Accidental drowning and submersion
0.655 0.345 0.000
W50-W64 Exposure to animate mechanical forces
0.655 0.345 0.000
V98-V99 Other and unspecified transport accidents
0.655 0.345 0.000
V95-V97 Air and space transport accidents
0.655 0.345 0.000
V90-V94 Water transport accidents
0.655 0.345 0.000
V80-V89 Other land transport accidents
0.655 0.345 0.000
V70-V79 Bus occupant injured in transport accident
0.655 0.345 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.655 0.345 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.655 0.345 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.655 0.345 0.000
V01-V09 Pedestrian injured in transport accident
0.655 0.345 0.000
H55-H59 Other disorders of eye and adnexa
0.655 0.345 0.000
H27.0 Aphakia
0.653 0.346 0.000
M51.2 Other specified intervertebral disk displacement
0.652 0.348 0.000
R40.2 Coma, unspecified
0.652 0.348 0.000
H04 Disorders of lachrymal system
0.652 0.348 0.000
O00-O08 Pregnancy with abortive outcome
0.652 0.348 0.000
L03.1 Cellulitis of other parts of limb
0.650 0.350 0.000
S80 Superficial injury of lower leg
0.650 0.350 0.000
R26 Abnormalities of gait and mobility
0.650 0.350 0.000
J36 Peritonsillar abscess
0.650 0.350 0.000
G90-G99 Other disorders of the nervous system
0.650 0.350 0.000
M65-M68 Disorders of synovium and tendon
0.649 0.350 0.000
M13.96 Arthritis, unspecified (Lower leg)
0.649 0.351 0.000
S64.4 Injury of digital nerve of other finger
0.649 0.351 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.648 0.352 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.648 0.352 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.647 0.352 0.000
S99 Other and unspecified injuries of ankle and foot
0.647 0.353 0.000
M06 Other rheumatoid arthritis
0.647 0.353 0.000
H72.2 Other marginal perforations of tympanic membrane
0.646 0.353 0.000
H72.1 Attic perforation of tympanic membrane
0.646 0.353 0.000
I77.1 Stricture of artery
0.646 0.354 0.000
S27 Injury of other and unspecified intrathoracic organs
0.646 0.354 0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction
0.646 0.354 0.000
J20-J22 Other acute lower respiratory infections
0.646 0.354 0.000
H93 Other disorders of ear, not elsewhere classified
0.645 0.355 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.645 0.355 0.000
N10 Acute tubulo-interstitial nephritis
0.645 0.355 0.000
N13.8 Other obstructive and reflux uropathy
0.644 0.356 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.644 0.356 0.000
T66-T78 Other and unspecified effects of external causes
0.644 0.356 0.000
R42 Dizziness and giddiness
0.643 0.357 0.000
T81.7 Vascular complications following a procedure, not elsewhere classified
0.642 0.358 0.000
T81.6 Acute reaction to foreign substance accidentally left during a procedure
0.642 0.358 0.000
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure
0.642 0.358 0.000
T81.1 Shock during or resulting from a procedure, not elsewhere classified
0.642 0.358 0.000
S90 Superficial injury of ankle and foot
0.642 0.358 0.000
M14 Arthropathies in other diseases classified elsewhere
0.642 0.358 0.000
M12 Other specific arthropathies
0.642 0.358 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.642 0.358 0.000
M08 Juvenile arthritis
0.642 0.358 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.642 0.358 0.000
Q80-Q89 Other congenital malformations
0.642 0.358 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.642 0.358 0.000
Q50-Q56 Congenital malformations of genital organs
0.642 0.358 0.000
Q35-Q37 Cleft lip and cleft palate
0.642 0.358 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.642 0.358 0.000
Q00-Q07 Congenital malformations of the nervous system
0.642 0.358 0.000
I71 Aortic aneurysm and dissection
0.641 0.359 0.000
H02.1 Ectropion of eyelid
0.641 0.359 0.000
M51.8 Other specified intervertebral disk disorders
0.640 0.360 0.000
E15 Nondiabetic hypoglycaemic coma
0.640 0.360 0.000
H02.9 Disorder of eyelid, unspecified
0.640 0.360 0.000
N30-N39 Other diseases of urinary system
0.640 0.360 0.000
I20-I25 Ischaemic heart diseases
0.639 0.361 0.000
S51.9 Open wound of forearm, part unspecified
0.639 0.361 0.000
M47 Spondylosis
0.639 0.361 0.000
R92 Abnormal findings on diagnostic imaging of breast
0.639 0.361 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.638 0.362 0.000
Q61.3 Polycystic kidney, unspecified
0.637 0.363 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.637 0.363 0.000
H05 Disorders of orbit
0.637 0.363 0.000
H03 Disorders of eyelid in diseases classified elsewhere
0.637 0.363 0.000
R47-R49 Symptoms and signs involving speech and voice
0.636 0.364 0.000
H02.6 Xanthelasma of eyelid
0.636 0.364 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.635 0.364 0.000
H25.1 Senile nuclear cataract
0.635 0.365 0.000
H62 Disorders of external ear in diseases classified elsewhere
0.635 0.365 0.000
C15 Malignant neoplasm of oesophagus
0.635 0.365 0.000
I21 Acute myocardial infarction
0.634 0.366 0.000
R36 Urethral discharge
0.634 0.366 0.000
J32.9 Chronic sinusitis, unspecified
0.634 0.366 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.633 0.367 0.000
M54.97 Dorsalgia, unspecified (Lumbosacral region)
0.633 0.367 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.633 0.367 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.633 0.367 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.633 0.367 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.633 0.367 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.633 0.367 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.633 0.367 0.000
T36 Poisoning by systemic antibiotics
0.633 0.367 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.633 0.367 0.000
R94 Abnormal results of function studies
0.633 0.367 0.000
R20.8 Other and unspecified disturbances of skin sensation
0.633 0.367 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.632 0.367 0.000
H02.3 Blepharochalasis
0.632 0.368 0.000
E11.8 With unspecified complications
0.631 0.369 0.000
E11.7 With multiple complications
0.631 0.369 0.000
E11.6 With other specified complications
0.631 0.369 0.000
E11.1 With ketoacidosis
0.631 0.369 0.000
E11.0 With coma
0.631 0.369 0.000
R93.1 Abnormal findings on diagnostic imaging of heart and coronary circulation
0.631 0.369 0.000
R44.3 Hallucinations, unspecified
0.631 0.369 0.000
N18.4 Chronic kidney disease, stage 4
0.630 0.370 0.000
N18.8 Other chronic renal failure
0.630 0.370 0.000
N18.1 Chronic kidney disease, stage 1
0.630 0.370 0.000
R40.0 Somnolence
0.630 0.370 0.000
N73 Other female pelvic inflammatory diseases
0.630 0.370 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.629 0.371 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.629 0.371 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.629 0.371 0.000
J37 Chronic laryngitis and laryngotracheitis
0.629 0.371 0.000
M40-M43 Deforming dorsopathies
0.628 0.371 0.000
H83 Other diseases of inner ear
0.628 0.372 0.000
M83 Adult osteomalacia
0.628 0.372 0.000
M82 Osteoporosis in diseases classified elsewhere
0.628 0.372 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.628 0.372 0.000
R23.8 Other and unspecified skin changes
0.627 0.373 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.627 0.373 0.000
S70 Superficial injury of hip and thigh
0.627 0.373 0.000
J32.2 Chronic ethmoidal sinusitis
0.627 0.373 0.000
S42.0 Fracture of clavicle
0.627 0.373 0.000
H66.3 Other chronic suppurative otitis media
0.627 0.373 0.000
G43.1 Migraine with aura [classical migraine]
0.626 0.374 0.000
N13.7 Vesicoureteral-reflux-associated uropathy
0.626 0.374 0.000
N13.6 Pyonephrosis
0.626 0.374 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.626 0.374 0.000
N13.5 Kinking and stricture of ureter without hydronephrosis
0.625 0.375 0.000
C67.9 Bladder, unspecified
0.624 0.376 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.624 0.376 0.000
M51.9 Intervertebral disk disorder, unspecified
0.624 0.376 0.000
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified
0.623 0.377 0.000
H40-H42 Glaucoma
0.623 0.377 0.000
C51-C58 Malignant neoplasms of female genital organs
0.622 0.378 0.000
T51 Toxic effect of alcohol
0.621 0.379 0.000
H25.2 Senile cataract, morgagnian type
0.620 0.379 0.000
N42 Other disorders of prostate
0.620 0.380 0.000
H02.7 Other degenerative disorders of eyelid and periocular area
0.619 0.380 0.000
H02.2 Lagophthalmos
0.619 0.380 0.000
J31.0 Chronic rhinitis
0.619 0.381 0.000
N04 Nephrotic syndrome
0.619 0.381 0.000
J41 Simple and mucopurulent chronic bronchitis
0.618 0.382 0.000
J46 Status asthmaticus
0.618 0.382 0.000
S40 Superficial injury of shoulder and upper arm
0.618 0.382 0.000
I21.9 Acute myocardial infarction, unspecified
0.618 0.382 0.000
G44.2 Tension-type headache
0.617 0.383 0.000
N07 Hereditary nephropathy, not elsewhere classified
0.617 0.383 0.000
N06 Isolated proteinuria with specified morphological lesion
0.617 0.383 0.000
N01 Rapidly progressive nephritic syndrome
0.617 0.383 0.000
N00 Acute nephritic syndrome
0.617 0.383 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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