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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs11644694
log Bayes Factor = 7.27682
Chromosome 16   position 58,557,342  (GRCh37) Explore rs11644694 on Ensembl!
Variant rs11644694 is part of Cluster X0111

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter V Mental and behavioural disorders
0.997 0.003 0.000
M20-M25 Other joint disorders
0.996 0.004 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.996 0.004 0.000
M25 Other joint disorders, not elsewhere classified
0.993 0.007 0.000
Chapter XX External causes of morbidity and mortality
0.991 0.009 0.000
F30-F39 Mood [affective] disorders
0.988 0.012 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.986 0.014 0.000
E65-E68 Obesity and other hyperalimentation
0.984 0.016 0.000
M25.5 Pain in joint
0.982 0.018 0.000
Chapter VI Diseases of the nervous system
0.977 0.023 0.000
Chapter VII Diseases of the eye and adnexa
0.973 0.027 0.000
T92 Sequelae of injuries of upper limb
0.972 0.028 0.000
E66 Obesity
0.971 0.029 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.967 0.033 0.000
M50-M54 Other dorsopathies
0.967 0.033 0.000
F32 Depressive episode
0.962 0.038 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.962 0.038 0.000
M54 Dorsalgia
0.957 0.043 0.000
E66.9 Obesity, unspecified
0.950 0.050 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.947 0.053 0.000
M25.55 Pain in joint (Pelvic region and thigh)
0.944 0.056 0.000
T51 Toxic effect of alcohol
0.943 0.057 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.938 0.062 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.937 0.063 0.000
M70-M79 Other soft tissue disorders
0.928 0.072 0.000
M40-M43 Deforming dorsopathies
0.924 0.076 0.000
T92.1 Sequelae of fracture of arm
0.922 0.078 0.000
M54.9 Dorsalgia, unspecified
0.917 0.083 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.913 0.087 0.000
S90-S99 Injuries to the ankle and foot
0.913 0.087 0.000
T51.0 Ethanol
0.912 0.088 0.000
E10-E14 Diabetes mellitus
0.906 0.094 0.000
M25.8 Other specified joint disorders
0.904 0.096 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.903 0.097 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.903 0.097 0.000
M54.99 Dorsalgia, unspecified (Site unspecified)
0.900 0.100 0.000
Y40 Systemic antibiotics
0.892 0.108 0.000
F32.2 Severe depressive episode without psychotic symptoms
0.891 0.109 0.000
G35 Multiple sclerosis
0.889 0.111 0.000
E14 Unspecified diabetes mellitus
0.888 0.112 0.000
M41 Scoliosis
0.883 0.117 0.000
M54.2 Cervicalgia
0.881 0.119 0.000
H30-H36 Disorders of choroid and retina
0.880 0.120 0.000
M25.7 Osteophyte
0.878 0.122 0.000
S20-S29 Injuries to the thorax
0.876 0.124 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.872 0.128 0.000
E14.9 Without complications
0.860 0.140 0.000
F43 Reaction to severe stress, and adjustment disorders
0.860 0.140 0.000
M91-M94 Chondropathies
0.858 0.142 0.000
M31 Other necrotising vasculopathies
0.857 0.143 0.000
M41.9 Scoliosis, unspecified
0.854 0.146 0.000
M25.51 Pain in joint (Shoulder region)
0.853 0.147 0.000
F33 Recurrent depressive disorder
0.850 0.150 0.000
M34 Systemic sclerosis
0.848 0.152 0.000
M25.54 Pain in joint (Hand)
0.847 0.153 0.000
M45-M49 Spondylopathies
0.846 0.154 0.000
E66.8 Other obesity
0.845 0.155 0.000
M54.6 Pain in thoracic spine
0.844 0.156 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.843 0.157 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.840 0.160 0.000
H25-H28 Disorders of lens
0.839 0.161 0.000
E00-E07 Disorders of thyroid gland
0.838 0.162 0.000
T92.5 Sequelae of injury of muscle and tendon of upper limb
0.835 0.165 0.000
M54.22 Cervicalgia (Cervical region)
0.834 0.166 0.000
T79-T79 Certain early complications of trauma
0.828 0.172 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.828 0.172 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.825 0.175 0.000
M25.58 Pain in joint (Other)
0.823 0.177 0.000
W50-W64 Exposure to animate mechanical forces
0.822 0.178 0.000
Y40.0 Penicillins
0.821 0.179 0.000
S10-S19 Injuries to the neck
0.819 0.181 0.000
F43.2 Adjustment disorders
0.817 0.183 0.000
E65 Localised adiposity
0.817 0.183 0.000
M25.84 Other specified joint disorders (Hand)
0.816 0.184 0.000
G81 Hemiplegia
0.815 0.185 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.814 0.186 0.000
G30-G32 Other degenerative diseases of the nervous system
0.813 0.187 0.000
T90 Sequelae of injuries of head
0.812 0.188 0.000
F60-F69 Disorders of adult personality and behaviour
0.810 0.190 0.000
M54.1 Radiculopathy
0.810 0.190 0.000
V80-V89 Other land transport accidents
0.807 0.193 0.000
G40-G47 Episodic and paroxysmal disorders
0.806 0.194 0.000
M25.3 Other instability of joint
0.806 0.194 0.000
T92.2 Sequelae of fracture at wrist and hand level
0.804 0.195 0.000
M25.76 Osteophyte (Lower leg)
0.802 0.198 0.000
Chapter X Diseases of the respiratory system
0.802 0.198 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.800 0.200 0.000
F41 Other anxiety disorders
0.800 0.200 0.000
H21 Other disorders of iris and ciliary body
0.799 0.201 0.000
T51.9 Alcohol, unspecified
0.797 0.202 0.000
H43-H45 Disorders of vitreous body and globe
0.797 0.203 0.000
J09-J18 Influenza and pneumonia
0.796 0.204 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.795 0.205 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.794 0.206 0.000
F34 Persistent mood [affective] disorders
0.793 0.207 0.000
F32.9 Depressive episode, unspecified
0.792 0.208 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.791 0.209 0.000
S32 Fracture of lumbar spine and pelvis
0.790 0.210 0.000
F32.3 Severe depressive episode with psychotic symptoms
0.789 0.211 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.789 0.211 0.000
T66-T78 Other and unspecified effects of external causes
0.788 0.212 0.000
M75 Shoulder lesions
0.788 0.212 0.000
M41.99 Scoliosis, unspecified (Site unspecified)
0.788 0.212 0.000
H35 Other retinal disorders
0.787 0.213 0.000
G37 Other demyelinating diseases of central nervous system
0.787 0.213 0.000
G83 Other paralytic syndromes
0.783 0.217 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.782 0.218 0.000
F31 Bipolar affective disorder
0.782 0.218 0.000
F32.1 Moderate depressive episode
0.782 0.218 0.000
T91 Sequelae of injuries of neck and trunk
0.780 0.220 0.000
M72 Fibroblastic disorders
0.779 0.221 0.000
S99 Other and unspecified injuries of ankle and foot
0.777 0.223 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.777 0.223 0.000
M25.87 Other specified joint disorders (Ankle and foot)
0.777 0.223 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.774 0.226 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.772 0.228 0.000
H55-H59 Other disorders of eye and adnexa
0.772 0.228 0.000
M53 Other dorsopathies, not elsewhere classified
0.771 0.229 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.770 0.230 0.000
T92.9 Sequelae of unspecified injury of upper limb
0.769 0.231 0.000
W00-W19 Falls
0.768 0.232 0.000
M00-M03 Infectious arthropathies
0.766 0.234 0.000
M41.96 Scoliosis, unspecified (Lumbar region)
0.766 0.234 0.000
F32.8 Other depressive episodes
0.765 0.235 0.000
M54.64 Pain in thoracic spine (Thoracic region)
0.764 0.236 0.000
H33 Retinal detachments and breaks
0.763 0.237 0.000
M22 Disorders of patella
0.763 0.237 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.761 0.239 0.000
E50-E64 Other nutritional deficiencies
0.759 0.241 0.000
T40.6 Other and unspecified narcotics
0.759 0.241 0.000
V01-V09 Pedestrian injured in transport accident
0.758 0.242 0.000
F80-F89 Disorders of psychological development
0.757 0.243 0.000
S91 Open wound of ankle and foot
0.756 0.244 0.000
Y40.9 Systemic antibiotic, unspecified
0.755 0.245 0.000
M25.53 Pain in joint (Forearm)
0.755 0.245 0.000
F40 Phobic anxiety disorders
0.754 0.246 0.000
Y48 Anaesthetics and therapeutic gases
0.753 0.247 0.000
E20-E35 Disorders of other endocrine glands
0.752 0.248 0.000
G81.9 Hemiplegia, unspecified
0.751 0.249 0.000
M21 Other acquired deformities of limbs
0.749 0.251 0.000
M23 Internal derangement of knee
0.748 0.252 0.000
T92.0 Sequelae of open wound of upper limb
0.746 0.254 0.000
J10 Influenza due to identified influenza virus
0.745 0.255 0.000
H16 Keratitis
0.745 0.255 0.000
H17 Corneal scars and opacities
0.745 0.255 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.743 0.257 0.000
X10-X19 Contact with heat and hot substances
0.743 0.257 0.000
M33 Dermatopolymyositis
0.743 0.257 0.000
H26 Other cataract
0.743 0.257 0.000
T40.2 Other opioids
0.742 0.258 0.000
M65-M68 Disorders of synovium and tendon
0.741 0.259 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.741 0.259 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.740 0.260 0.000
M54.3 Sciatica
0.740 0.260 0.000
Chapter XXII Codes for special purposes
0.740 0.260 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.739 0.261 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.739 0.261 0.000
E40-E46 Malnutrition
0.738 0.262 0.000
S22.0 Fracture of thoracic vertebra
0.736 0.264 0.000
F48 Other neurotic disorders
0.734 0.266 0.000
H31 Other disorders of choroid
0.733 0.267 0.000
M94 Other disorders of cartilage
0.732 0.268 0.000
J95-J99 Other diseases of the respiratory system
0.731 0.269 0.000
F99-F99 Unspecified mental disorder
0.730 0.270 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.728 0.272 0.000
S92 Fracture of foot, except ankle
0.727 0.272 0.000
T63 Toxic effect of contact with venomous animals
0.726 0.273 0.000
T00-T07 Injuries involving multiple body regions
0.726 0.274 0.000
M60-M63 Disorders of muscles
0.725 0.274 0.000
G70-G73 Diseases of myoneural junction and muscle
0.724 0.276 0.000
E14.3 With ophthalmic complications
0.724 0.276 0.000
H35.3 Degeneration of macula and posterior pole
0.724 0.276 0.000
X60-X84 Intentional self-harm
0.723 0.277 0.000
E05.9 Thyrotoxicosis, unspecified
0.723 0.277 0.000
Y52 Agents primarily affecting the cardiovascular system
0.722 0.278 0.000
T36 Poisoning by systemic antibiotics
0.721 0.279 0.000
X20-X29 Contact with venomous animals and plants
0.719 0.281 0.000
M25.50 Pain in joint (Multiple sites)
0.718 0.282 0.000
M31.3 Wegener's granulomatosis
0.718 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.715 0.285 0.000
F70-F79 Mental retardation
0.715 0.285 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.714 0.286 0.000
M32 Systemic lupus erythematosus
0.714 0.286 0.000
M30 Polyarteritis nodosa and related conditions
0.714 0.286 0.000
F05 Delirium, not induced by alcohol and other psychoactive substances
0.713 0.287 0.000
E14.4 With neurological complications
0.712 0.287 0.000
M25.2 Flail joint
0.712 0.288 0.000
M25.1 Fistula of joint
0.712 0.288 0.000
M34.8 Other forms of systemic sclerosis
0.712 0.288 0.000
Y00-Y09 Assault
0.712 0.288 0.000
Y86 Sequelae of other accidents
0.711 0.289 0.000
Y35-Y36 Legal intervention and operations of war
0.711 0.289 0.000
Y10-Y34 Event of undetermined intent
0.711 0.289 0.000
X85-X99 Assault
0.711 0.289 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.711 0.289 0.000
X30-X39 Exposure to forces of nature
0.711 0.289 0.000
X00-X09 Exposure to smoke, fire and flames
0.711 0.289 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.711 0.289 0.000
W75-W84 Other accidental threats to breathing
0.711 0.289 0.000
W65-W74 Accidental drowning and submersion
0.711 0.289 0.000
V98-V99 Other and unspecified transport accidents
0.711 0.289 0.000
V95-V97 Air and space transport accidents
0.711 0.289 0.000
V90-V94 Water transport accidents
0.711 0.289 0.000
V70-V79 Bus occupant injured in transport accident
0.711 0.289 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.711 0.289 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.711 0.289 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.711 0.289 0.000
F38 Other mood [affective] disorders
0.708 0.291 0.000
F30 Manic episode
0.708 0.291 0.000
F39 Unspecified mood [affective] disorder
0.708 0.291 0.000
V10-V19 Pedal cyclist injured in transport accident
0.707 0.292 0.000
M79.2 Neuralgia and neuritis, unspecified
0.707 0.293 0.000
T95 Sequelae of burns, corrosions and frostbite
0.707 0.293 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.707 0.293 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.707 0.293 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.706 0.294 0.000
E67 Other hyperalimentation
0.706 0.294 0.000
E68 Sequelae of hyperalimentation
0.706 0.294 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.706 0.294 0.000
X50-X57 Overexertion, travel and privation
0.705 0.295 0.000
M86-M90 Other osteopathies
0.705 0.295 0.000
J18 Pneumonia, organism unspecified
0.702 0.298 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.702 0.298 0.000
M25.59 Pain in joint (Site unspecified)
0.701 0.299 0.000
G40 Epilepsy
0.701 0.299 0.000
F41.2 Mixed anxiety and depressive disorder
0.701 0.299 0.000
M75.4 Impingement syndrome of shoulder
0.700 0.300 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.699 0.301 0.000
M25.77 Osteophyte (Ankle and foot)
0.699 0.301 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.698 0.302 0.000
S80-S89 Injuries to the knee and lower leg
0.698 0.302 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.698 0.302 0.000
M25.0 Haemarthrosis
0.697 0.303 0.000
V40-V49 Car occupant injured in transport accident
0.697 0.303 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.697 0.303 0.000
T92.8 Sequelae of other specified injuries of upper limb
0.697 0.303 0.000
T92.6 Sequelae of crushing injury and traumatic amputation of upper limb
0.697 0.303 0.000
T92.4 Sequelae of injury of nerve of upper limb
0.697 0.303 0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere
0.697 0.303 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.696 0.304 0.000
E66.2 Extreme obesity with alveolar hypoventilation
0.696 0.304 0.000
E66.1 Drug-induced obesity
0.696 0.304 0.000
E66.0 Obesity due to excess calories
0.696 0.304 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.696 0.304 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.696 0.304 0.000
S22.00 Fracture of thoracic vertebra (closed)
0.694 0.306 0.000
M91 Juvenile osteochondrosis of hip and pelvis
0.694 0.306 0.000
T65 Toxic effect of other and unspecified substances
0.693 0.306 0.000
T62 Toxic effect of other noxious substances eaten as food
0.693 0.306 0.000
T61 Toxic effect of noxious substances eaten as seafood
0.693 0.306 0.000
T60 Toxic effect of pesticides
0.693 0.306 0.000
T57 Toxic effect of other inorganic substances
0.693 0.306 0.000
T56 Toxic effect of metals
0.693 0.306 0.000
T54 Toxic effect of corrosive substances
0.693 0.306 0.000
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone
0.693 0.306 0.000
T52 Toxic effect of organic solvents
0.693 0.306 0.000
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants
0.693 0.306 0.000
T58 Toxic effect of carbon monoxide
0.693 0.306 0.000
T55 Toxic effect of soaps and detergents
0.693 0.306 0.000
M79.1 Myalgia
0.694 0.306 0.000
M80-M85 Disorders of bone density and structure
0.692 0.308 0.000
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms
0.690 0.310 0.000
W20-W49 Exposure to inanimate mechanical forces
0.690 0.310 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.690 0.310 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.690 0.310 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.690 0.310 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.690 0.310 0.000
F31.9 Bipolar affective disorder, unspecified
0.689 0.311 0.000
S50-S59 Injuries to the elbow and forearm
0.689 0.311 0.000
H10-H13 Disorders of conjunctiva
0.687 0.313 0.000
M54.8 Other dorsalgia
0.686 0.314 0.000
M54.0 Panniculitis affecting regions of neck and back
0.686 0.314 0.000
M46 Other inflammatory spondylopathies
0.685 0.315 0.000
J10.1 Influenza with other respiratory manifestations, influenza virus identified
0.682 0.318 0.000
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms
0.680 0.320 0.000
Y40.8 Other systemic antibiotics
0.680 0.320 0.000
S99.9 Unspecified injury of ankle and foot
0.679 0.320 0.000
G37.9 Demyelinating disease of central nervous system, unspecified
0.679 0.321 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.679 0.321 0.000
F44 Dissociative [conversion] disorders
0.679 0.321 0.000
G83.4 Cauda equina syndrome
0.678 0.322 0.000
M25.85 Other specified joint disorders (Pelvic region and thigh)
0.678 0.322 0.000
T92.3 Sequelae of dislocation, sprain and strain of upper limb
0.677 0.323 0.000
T51.8 Other alcohols
0.676 0.324 0.000
T51.3 Fusel oil
0.676 0.324 0.000
T51.2 2-Propanol
0.676 0.324 0.000
T51.1 Methanol
0.676 0.324 0.000
F60 Specific personality disorders
0.676 0.324 0.000
Y89 Sequelae of other external causes
0.676 0.324 0.000
T90.4 Sequelae of injury of eye and orbit
0.676 0.324 0.000
F33.0 Recurrent depressive disorder, current episode mild
0.675 0.324 0.000
M25.72 Osteophyte (Upper arm)
0.675 0.325 0.000
V89 Motor- or nonmotor-vehicle accident, type of vehicle unspecified
0.674 0.326 0.000
M25.57 Pain in joint (Ankle and foot)
0.673 0.327 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.673 0.327 0.000
G36 Other acute disseminated demyelination
0.672 0.328 0.000
Y59 Other and unspecified vaccines and biological substances
0.672 0.328 0.000
Y58 Bacterial vaccines
0.672 0.328 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.672 0.328 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.672 0.328 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.672 0.328 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.672 0.328 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.672 0.328 0.000
M54.90 Dorsalgia, unspecified (Multiple sites in spine)
0.672 0.328 0.000
W10 Fall on and from stairs and steps
0.671 0.329 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.670 0.330 0.000
M54.17 Radiculopathy (Lumbosacral region)
0.668 0.331 0.000
F42 Obsessive-compulsive disorder
0.668 0.332 0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica
0.668 0.332 0.000
M72.0 Palmar fascial fibromatosis [Dupuytren]
0.667 0.333 0.000
T59 Toxic effect of other gases, fumes and vapours
0.666 0.334 0.000
Y57 Other and unspecified drugs and medicaments
0.666 0.334 0.000
J99 Respiratory disorders in diseases classified elsewhere
0.666 0.334 0.000
W55 Bitten or struck by other mammals
0.666 0.334 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.665 0.334 0.000
H43 Disorders of vitreous body
0.665 0.335 0.000
G20-G26 Extrapyramidal and movement disorders
0.665 0.335 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.664 0.336 0.000
H21.0 Hyphaema
0.664 0.336 0.000
M25.74 Osteophyte (Hand)
0.664 0.336 0.000
J17 Pneumonia in diseases classified elsewhere
0.664 0.336 0.000
T98 Sequelae of other and unspecified effects of external causes
0.663 0.337 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.663 0.337 0.000
M42 Spinal osteochondrosis
0.663 0.337 0.000
M40 Kyphosis and lordosis
0.663 0.337 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.662 0.338 0.000
M25.52 Pain in joint (Upper arm)
0.661 0.339 0.000
M34.9 Systemic sclerosis, unspecified
0.660 0.340 0.000
H35.6 Retinal haemorrhage
0.660 0.340 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.660 0.340 0.000
M25.4 Effusion of joint
0.659 0.340 0.000
Q80-Q89 Other congenital malformations
0.659 0.341 0.000
M76 Enthesopathies of lower limb, excluding foot
0.658 0.341 0.000
M54.98 Dorsalgia, unspecified (Sacral and sacrococcygeal region)
0.658 0.342 0.000
M54.97 Dorsalgia, unspecified (Lumbosacral region)
0.658 0.342 0.000
M54.95 Dorsalgia, unspecified (Thoracolumbar region)
0.658 0.342 0.000
M54.93 Dorsalgia, unspecified (Cervicothoracic region)
0.658 0.342 0.000
M54.92 Dorsalgia, unspecified (Cervical region)
0.658 0.342 0.000
M54.91 Dorsalgia, unspecified (Occipito-atlanto-axial region)
0.658 0.342 0.000
H00 Hordeolum and chalazion
0.657 0.343 0.000
S22.2 Fracture of sternum
0.656 0.344 0.000
M47 Spondylosis
0.656 0.344 0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere
0.655 0.345 0.000
H15 Disorders of sclera
0.655 0.345 0.000
S29 Other and unspecified injuries of thorax
0.655 0.345 0.000
S98 Traumatic amputation of ankle and foot
0.654 0.345 0.000
S97 Crushing injury of ankle and foot
0.654 0.345 0.000
S96 Injury of muscle and tendon at ankle and foot level
0.654 0.345 0.000
S95 Injury of blood vessels at ankle and foot level
0.654 0.345 0.000
S94 Injury of nerves at ankle and foot level
0.654 0.345 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.654 0.345 0.000
S32.0 Fracture of lumbar vertebra
0.654 0.346 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.653 0.347 0.000
F34.1 Dysthymia
0.653 0.347 0.000
S30.1 Contusion of abdominal wall
0.652 0.347 0.000
H57 Other disorders of eye and adnexa
0.652 0.348 0.000
H21.8 Other specified disorders of iris and ciliary body
0.652 0.348 0.000
M25.37 Other instability of joint (Ankle and foot)
0.652 0.348 0.000
H35.5 Hereditary retinal dystrophy
0.651 0.349 0.000
M75.9 Shoulder lesion, unspecified
0.650 0.349 0.000
E12 Malnutrition-related diabetes mellitus
0.650 0.350 0.000
H18 Other disorders of cornea
0.649 0.351 0.000
M25.89 Other specified joint disorders (Site unspecified)
0.648 0.351 0.000
M25.88 Other specified joint disorders (Other)
0.648 0.351 0.000
M25.83 Other specified joint disorders (Forearm)
0.648 0.351 0.000
M25.82 Other specified joint disorders (Upper arm)
0.648 0.351 0.000
M25.81 Other specified joint disorders (Shoulder region)
0.648 0.351 0.000
M25.80 Other specified joint disorders (Multiple sites)
0.648 0.351 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.648 0.352 0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis
0.648 0.352 0.000
S37 Injury of urinary and pelvic organs
0.648 0.352 0.000
S36 Injury of intra-abdominal organs
0.648 0.352 0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level
0.648 0.352 0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level
0.648 0.352 0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis
0.648 0.352 0.000
S31 Open wound of abdomen, lower back and pelvis
0.648 0.352 0.000
G80 Infantile cerebral palsy
0.647 0.352 0.000
H20 Iridocyclitis
0.647 0.353 0.000
S81 Open wound of lower leg
0.647 0.353 0.000
H26.2 Complicated cataract
0.647 0.353 0.000
M24 Other specific joint derangements
0.646 0.353 0.000
Y40.1 Cefalosporins and other -lactam antibiotics
0.646 0.354 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.646 0.354 0.000
M49 Spondylopathies in diseases classified elsewhere
0.646 0.354 0.000
M25.78 Osteophyte (Other)
0.646 0.354 0.000
Y44 Agents primarily affecting blood constituents
0.645 0.355 0.000
Y87 Sequelae of intentional self-harm, assault and events of undetermined intent
0.645 0.355 0.000
S91.3 Open wound of other parts of foot
0.643 0.357 0.000
F33.1 Recurrent depressive disorder, current episode moderate
0.643 0.357 0.000
W50 Hit, struck, kicked, twisted, bitten or scratched by another person
0.643 0.357 0.000
M23.8 Other internal derangements of knee
0.643 0.357 0.000
F01 Vascular dementia
0.642 0.357 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.641 0.358 0.000
M79.6 Pain in limb
0.641 0.359 0.000
M41.94 Scoliosis, unspecified (Thoracic region)
0.641 0.359 0.000
S90 Superficial injury of ankle and foot
0.641 0.359 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.640 0.360 0.000
Y40.7 Antifungal antibiotics, systemically used
0.640 0.360 0.000
Y40.6 Rifamycins
0.640 0.360 0.000
Y40.5 Aminoglycosides
0.640 0.360 0.000
Y40.4 Tetracyclines
0.640 0.360 0.000
Y40.3 Macrolides
0.640 0.360 0.000
Y40.2 Chloramphenicol group
0.640 0.360 0.000
S32.5 Fracture of pubis
0.640 0.360 0.000
M25.9 Joint disorder, unspecified
0.639 0.361 0.000
V20-V29 Motorcycle rider injured in transport accident
0.638 0.362 0.000
J18.1 Lobar pneumonia, unspecified
0.637 0.363 0.000
M22.4 Chondromalacia patellae
0.637 0.363 0.000
E14.8 With unspecified complications
0.637 0.363 0.000
E14.7 With multiple complications
0.637 0.363 0.000
E14.6 With other specified complications
0.637 0.363 0.000
E14.5 With peripheral circulatory complications
0.637 0.363 0.000
E14.2 Withrenal complications
0.637 0.363 0.000
E14.1 With ketoacidosis
0.637 0.363 0.000
E14.0 With coma
0.637 0.363 0.000
S10 Superficial injury of neck
0.637 0.363 0.000
E13 Other specified diabetes mellitus
0.637 0.363 0.000
M31.6 Other giant cell arteritis
0.636 0.364 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.635 0.364 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.635 0.365 0.000
M94.9 Disorder of cartilage, unspecified
0.634 0.366 0.000
M41.8 Other forms of scoliosis
0.633 0.367 0.000
M41.5 Other secondary scoliosis
0.633 0.367 0.000
M41.4 Neuromuscular scoliosis
0.633 0.367 0.000
M41.3 Thoracogenic scoliosis
0.633 0.367 0.000
M41.2 Other idiopathic scoliosis
0.633 0.367 0.000
M41.1 Juvenile idiopathic scoliosis
0.633 0.367 0.000
M41.0 Infantile idiopathic scoliosis
0.633 0.367 0.000
Y43 Primarily systemic agents
0.632 0.368 0.000
M54.28 Cervicalgia-Sacral/sacrococ
0.632 0.368 0.000
M54.27 Cervicalgia-Lumbosacral
0.632 0.368 0.000
M54.26 Cervicalgia-Lumbar
0.632 0.368 0.000
M54.25 Cervicalgia-Thoracolumbar
0.632 0.368 0.000
M54.24 Cervicalgia-Thoracic
0.632 0.368 0.000
M54.23 Cervicalgia (Cervicothoracic region)
0.632 0.368 0.000
M54.21 Cervicalgia (Occipito-atlanto-axial region)
0.632 0.368 0.000
M54.20 Cervicalgia-Mult site
0.632 0.368 0.000
M54.16 Radiculopathy (Lumbar region)
0.631 0.368 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.631 0.369 0.000
H30 Chorioretinal inflammation
0.631 0.369 0.000
M53.3 Sacrococcygeal disorders, not elsewhere classified
0.630 0.370 0.000
S11 Open wound of neck
0.630 0.370 0.000
M25.79 Osteophyte (Site unspecified)
0.629 0.371 0.000
M25.73 Osteophyte (Forearm)
0.629 0.371 0.000
M25.70 Osteophyte (Multiple sites)
0.629 0.371 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.628 0.372 0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax
0.628 0.372 0.000
S26 Injury of heart
0.628 0.372 0.000
S25 Injury of blood vessels of thorax
0.628 0.372 0.000
S24 Injury of nerves and spinal cord at thorax level
0.628 0.372 0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax
0.628 0.372 0.000
S21 Open wound of thorax
0.628 0.372 0.000
H25 Senile cataract
0.628 0.372 0.000
T23 Burn and corrosion of wrist and hand
0.627 0.372 0.000
H31.0 Chorioretinal scars
0.627 0.373 0.000
J10.0 Influenza with pneumonia, influenza virus identified
0.626 0.374 0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]
0.625 0.375 0.000
T40.8 Lysergide [LSD]
0.625 0.375 0.000
T40.7 Cannabis (derivatives)
0.625 0.375 0.000
T40.5 Cocaine
0.625 0.375 0.000
T40.3 Methadone
0.625 0.375 0.000
T40.1 Heroin
0.625 0.375 0.000
T40.0 Opium
0.625 0.375 0.000
S30.0 Contusion of lower back and pelvis
0.625 0.375 0.000
Y95 Nosocomial condition
0.625 0.375 0.000
H16.0 Corneal ulcer
0.625 0.375 0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level
0.625 0.375 0.000
Chapter VIII Diseases of the ear and mastoid process
0.625 0.375 0.000
H17.9 Corneal scar and opacity, unspecified
0.625 0.375 0.000
M71 Other bursopathies
0.624 0.376 0.000
F03 Unspecified dementia
0.624 0.376 0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes
0.624 0.376 0.000
F41.1 Generalised anxiety disorder
0.623 0.377 0.000
M79.0 Rheumatism, unspecified
0.622 0.378 0.000
M23.29 Derangement of meniscus due to old tear or injury (Unspecified ligament or Unspecified meniscus)
0.622 0.378 0.000
Y48.3 Local anaesthetics
0.620 0.379 0.000
H26.1 Traumatic cataract
0.620 0.380 0.000
W08 Fall involving other furniture
0.619 0.381 0.000
M47.9 Spondylosis, unspecified
0.619 0.381 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.619 0.381 0.000
M54.94 Dorsalgia, unspecified (Thoracic region)
0.618 0.382 0.000
T47.1 Other antacids and anti-gastric-secretion drugs
0.618 0.382 0.000
F43.9 Reaction to severe stress, unspecified
0.617 0.383 0.000
F43.8 Other reactions to severe stress
0.617 0.383 0.000
H47 Other disorders of optic [2nd] nerve and visual pathways
0.616 0.384 0.000
F40.2 Specific (isolated) phobias
0.616 0.384 0.000
E16 Other disorders of pancreatic internal secretion
0.615 0.385 0.000
M92 Other juvenile osteochondrosis
0.615 0.385 0.000
M31.9 Necrotising vasculopathy, unspecified
0.615 0.385 0.000
M31.8 Other specified necrotising vasculopathies
0.615 0.385 0.000
M31.7 Microscopic polyangiitis
0.615 0.385 0.000
M31.4 Aortic arch syndrome [Takayasu]
0.615 0.385 0.000
M31.2 Lethal midline granuloma
0.615 0.385 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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