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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs116518618
log Bayes Factor = 85.1896
Chromosome 6   position 32,594,998  (GRCh37) Explore rs116518618 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
J45.9 Asthma, unspecified
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
# Top node
0.000 0.000 1.000
Chapter X Diseases of the respiratory system
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.000 0.000 1.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.000 1.000
G35 Multiple sclerosis
0.000 0.001 0.999
J45 Asthma
0.000 0.001 0.999
J40-J47 Chronic lower respiratory diseases
0.000 0.001 0.999
G35-G37 Demyelinating diseases of the central nervous system
0.000 0.001 0.999
E05.9 Thyrotoxicosis, unspecified
0.000 0.002 0.998
D60-D64 Aplastic and other anaemias
0.000 0.002 0.998
Chapter VI Diseases of the nervous system
0.000 0.002 0.998
D64 Other anaemias
0.000 0.004 0.996
D64.9 Anaemia, unspecified
0.000 0.004 0.996
Chapter II Neoplasms
0.000 0.004 0.996
D06.9 Cervix, unspecified
0.000 0.005 0.995
E11 Non-insulin-dependent diabetes mellitus
0.000 0.005 0.995
D06 Carcinoma in situ of cervix uteri
0.000 0.005 0.995
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.000 0.005 0.995
D00-D09 In situ neoplasms
0.000 0.006 0.994
J33.9 Nasal polyp, unspecified
0.000 0.009 0.991
M06 Other rheumatoid arthritis
0.000 0.009 0.991
J33 Nasal polyp
0.000 0.009 0.991
Chapter I Certain infectious and parasitic diseases
0.000 0.010 0.990
E10.3 With ophthalmic complications
0.000 0.010 0.990
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.000 0.011 0.989
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.000 0.014 0.986
J30-J39 Other diseases of upper respiratory tract
0.000 0.019 0.981
J33.0 Polyp of nasal cavity
0.000 0.022 0.978
E11.3 With ophthalmic complications
0.000 0.022 0.978
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.000 0.026 0.974
D50-D53 Nutritional anaemias
0.000 0.026 0.974
M05-M14 Inflammatory polyarthropathies
0.000 0.028 0.972
M05 Seropositive rheumatoid arthritis
0.000 0.032 0.968
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.035 0.965
D51 Vitamin B12 deficiency anaemia
0.000 0.037 0.963
A50-A64 Infections with a predominantly sexual mode of transmission
0.000 0.039 0.961
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.044 0.956
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.000 0.046 0.954
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.046 0.954
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.000 0.052 0.948
A63 Other predominantly sexually transmitted diseases, not elsewhere classified
0.000 0.059 0.941
G70-G73 Diseases of myoneural junction and muscle
0.000 0.060 0.940
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.066 0.934
C09 Malignant neoplasm of tonsil
0.000 0.068 0.932
B35-B49 Mycoses
0.000 0.069 0.931
A63.0 Anogenital (venereal) warts
0.000 0.073 0.927
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.074 0.926
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.075 0.925
J95-J99 Other diseases of the respiratory system
0.000 0.089 0.911
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.090 0.910
C83 Diffuse non-Hodgkin's lymphoma
0.000 0.093 0.907
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.000 0.094 0.906
C09.9 Tonsil, unspecified
0.000 0.098 0.902
E10.4 With neurological complications
0.000 0.101 0.899
B37 Candidiasis
0.000 0.110 0.890
K90 Intestinal malabsorption
0.000 0.121 0.879
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.000 0.121 0.879
G37 Other demyelinating diseases of central nervous system
0.000 0.123 0.877
J95 Postprocedural respiratory disorders, not elsewhere classified
0.000 0.128 0.872
G70 Myasthenia gravis and other myoneural disorders
0.000 0.129 0.871
E10.5 With peripheral circulatory complications
0.000 0.132 0.868
M06.0 Seronegative rheumatoid arthritis
0.000 0.137 0.863
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.138 0.862
C83.3 Large cell (diffuse)
0.000 0.138 0.862
E06 Thyroiditis
0.000 0.140 0.860
J95.8 Other postprocedural respiratory disorders
0.000 0.146 0.854
E10.2 With renal complications
0.000 0.150 0.850
D63 Anaemia in chronic diseases classified elsewhere
0.000 0.151 0.849
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.152 0.848
B37.0 Candidal stomatitis
0.000 0.161 0.839
E11.9 Without complications
0.000 0.161 0.839
J47 Bronchiectasis
0.000 0.164 0.836
B95-B98 Bacterial, viral and other infectious agents
0.000 0.164 0.836
C02 Malignant neoplasm of other and unspecified parts of tongue
0.000 0.165 0.835
K90-K93 Other diseases of the digestive system
0.000 0.165 0.835
E50-E64 Other nutritional deficiencies
0.000 0.167 0.833
Chapter XXII Codes for special purposes
0.000 0.167 0.833
E11.5 With peripheral circulatory complications
0.000 0.168 0.832
J80-J84 Other respiratory diseases principally affecting the interstitium
0.000 0.170 0.830
G80-G83 Cerebral palsy and other paralytic syndromes
0.000 0.171 0.829
C85.1 B-cell lymphoma, unspecified
0.000 0.172 0.828
Chapter XI Diseases of the digestive system
0.000 0.173 0.827
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.000 0.174 0.826
G70.0 Myasthenia gravis
0.000 0.178 0.822
B07 Viral warts
0.000 0.181 0.819
D70-D77 Other diseases of blood and blood-forming organs
0.000 0.181 0.819
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.000 0.181 0.819
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.182 0.818
E14 Unspecified diabetes mellitus
0.000 0.184 0.815
E11.4 With neurological complications
0.000 0.185 0.815
J46 Status asthmaticus
0.000 0.189 0.811
E11.0 With coma
0.000 0.191 0.809
A80-A89 Viral infections of the central nervous system
0.000 0.192 0.808
J00-J06 Acute upper respiratory infections
0.000 0.195 0.805
E10.1 With ketoacidosis
0.000 0.198 0.802
C43-C44 Melanoma and other malignant neoplasms of skin
0.000 0.200 0.800
K35-K38 Diseases of appendix
0.000 0.205 0.795
E07 Other disorders of thyroid
0.000 0.207 0.793
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.214 0.786
G37.9 Demyelinating disease of central nervous system, unspecified
0.000 0.219 0.781
G72 Other myopathies
0.000 0.219 0.781
J84 Other interstitial pulmonary diseases
0.000 0.222 0.778
E06.3 Autoimmune thyroiditis
0.000 0.225 0.775
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.226 0.774
E14.3 With ophthalmic complications
0.000 0.229 0.771
B20-B24 Human immunodeficiency virus [HIV] disease
0.000 0.230 0.770
B44 Aspergillosis
0.000 0.235 0.765
E53 Deficiency of other B group vitamins
0.000 0.235 0.765
J02 Acute pharyngitis
0.000 0.237 0.763
B97 Viral agents as the cause of diseases classified to other chapters
0.000 0.237 0.763
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.000 0.240 0.760
C07 Malignant neoplasm of parotid gland
0.000 0.240 0.760
M06.3 Rheumatoid nodule
0.000 0.245 0.755
C01 Malignant neoplasm of base of tongue
0.000 0.245 0.755
D63.0 Anaemia in neoplastic disease
0.000 0.247 0.752
J32 Chronic sinusitis
0.000 0.248 0.752
D52 Folate deficiency anaemia
0.000 0.251 0.749
E13 Other specified diabetes mellitus
0.000 0.251 0.749
J84.1 Other interstitial pulmonary diseases with fibrosis
0.000 0.252 0.748
K35 Acute appendicitis
0.000 0.253 0.747
D04 Carcinoma in situ of skin
0.000 0.253 0.747
A30-A49 Other bacterial diseases
0.000 0.255 0.745
G81 Hemiplegia
0.000 0.256 0.744
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.257 0.743
C10 Malignant neoplasm of oropharynx
0.000 0.258 0.742
M11 Other crystal arthropathies
0.000 0.258 0.742
M06.4 Inflammatory polyarthropathy
0.000 0.259 0.741
B37.3 Candidiasis of vulva and vagina
0.000 0.260 0.740
E16 Other disorders of pancreatic internal secretion
0.000 0.261 0.739
G63 Polyneuropathy in diseases classified elsewhere
0.000 0.266 0.734
C44 Other malignant neoplasms of skin
0.000 0.266 0.734
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.267 0.733
J02.9 Acute pharyngitis, unspecified
0.000 0.268 0.732
J33.8 Other polyp of sinus
0.000 0.268 0.732
J99 Respiratory disorders in diseases classified elsewhere
0.000 0.269 0.731
C44.3 Skin of other and unspecified parts of face
0.000 0.273 0.727
B37.8 Candidiasis of other sites
0.000 0.274 0.726
M10 Gout
0.000 0.274 0.726
J60-J70 Lung diseases due to external agents
0.000 0.281 0.719
E11.8 With unspecified complications
0.000 0.283 0.717
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.000 0.283 0.717
M14 Arthropathies in other diseases classified elsewhere
0.000 0.283 0.717
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.283 0.717
E10.6 With other specified complications
0.000 0.283 0.717
E10.0 With coma
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.1 Congenital hypothyroidism without goitre
0.000 0.283 0.717
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.717
E05.8 Other thyrotoxicosis
0.000 0.283 0.717
E05.5 Thyroid crisis or storm
0.000 0.283 0.717
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.717
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.283 0.717
J45.8 Mixed asthma
0.000 0.283 0.716
J45.1 Nonallergic asthma
0.000 0.283 0.716
C02.9 Tongue, unspecified
0.000 0.284 0.716
J41 Simple and mucopurulent chronic bronchitis
0.000 0.284 0.716
E53.8 Deficiency of other specified B group vitamins
0.000 0.284 0.716
G36 Other acute disseminated demyelination
0.000 0.284 0.716
B95.4 Other streptococcus as the cause of diseases classified to other chapters
0.000 0.284 0.716
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.000 0.285 0.715
D05 Carcinoma in situ of breast
0.000 0.285 0.715
D64.4 Congenital dyserythropoietic anaemia
0.000 0.286 0.714
D64.3 Other sideroblastic anaemias
0.000 0.286 0.714
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.000 0.286 0.714
D64.1 Secondary sideroblastic anaemia due to disease
0.000 0.286 0.714
D64.0 Hereditary sideroblastic anaemia
0.000 0.286 0.714
C40-C41 Malignant neoplasms of bone and articular cartilage
0.000 0.286 0.714
E11.7 With multiple complications
0.000 0.287 0.713
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.000 0.287 0.713
D06.7 Other parts of cervix
0.000 0.287 0.713
D06.1 Exocervix
0.000 0.287 0.713
D06.0 Endocervix
0.000 0.287 0.713
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.000 0.287 0.713
C95 Leukaemia of unspecified cell type
0.000 0.287 0.713
C94 Other leukaemias of specified cell type
0.000 0.287 0.713
C93 Monocytic leukaemia
0.000 0.287 0.713
C86 Other specified types of T/NK-cell lymphoma
0.000 0.287 0.713
D01 Carcinoma in situ of other and unspecified digestive organs
0.000 0.287 0.713
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.000 0.287 0.713
B97.7 Papillomavirus as the cause of diseases classified to other chapters
0.000 0.287 0.713
M06.8 Other specified rheumatoid arthritis
0.000 0.289 0.710
M06.2 Rheumatoid bursitis
0.000 0.289 0.710
M06.1 Adult-onset Still's disease
0.000 0.289 0.710
B85-B89 Pediculosis, acariasis and other infestations
0.000 0.290 0.710
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.000 0.290 0.710
A75-A79 Rickettsioses
0.000 0.290 0.710
A70-A74 Other diseases caused by chlamydiae
0.000 0.290 0.710
A20-A28 Certain zoonotic bacterial diseases
0.000 0.290 0.710
C82.7 Other types of follicular non-Hodgkin's lymphoma
0.000 0.291 0.709
C82.6 Cutaneous follicle centre lymphoma
0.000 0.291 0.709
C82.5 Diffuse follicle centre lymphoma
0.000 0.291 0.709
C82.4 Follicular lymphoma grade IIIb
0.000 0.291 0.709
C82.3 Follicular lymphoma grade IIIa
0.000 0.291 0.709
C82.2 Large cell, follicular
0.000 0.291 0.709
C82.1 Mixed small cleaved and large cell, follicular
0.000 0.291 0.709
C82.0 Small cleaved cell, follicular
0.000 0.291 0.709
A15-A19 Tuberculosis
0.000 0.294 0.706
C92 Myeloid leukaemia
0.000 0.294 0.706
B00 Herpesviral [herpes simplex] infections
0.000 0.299 0.701
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.000 0.301 0.699
C13 Malignant neoplasm of hypopharynx
0.000 0.301 0.699
C11 Malignant neoplasm of nasopharynx
0.000 0.301 0.699
C08 Malignant neoplasm of other and unspecified major salivary glands
0.000 0.301 0.699
C06 Malignant neoplasm of other and unspecified parts of mouth
0.000 0.301 0.699
C04 Malignant neoplasm of floor of mouth
0.000 0.301 0.699
C03 Malignant neoplasm of gum
0.000 0.301 0.699
C00 Malignant neoplasm of lip
0.000 0.301 0.699
C12 Malignant neoplasm of pyriform sinus
0.000 0.301 0.699
D07 Carcinoma in situ of other and unspecified genital organs
0.000 0.302 0.698
D53 Other nutritional anaemias
0.000 0.302 0.698
E07.9 Disorder of thyroid, unspecified
0.000 0.302 0.698
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.303 0.697
M08 Juvenile arthritis
0.000 0.303 0.697
E11.6 With other specified complications
0.000 0.303 0.696
A87 Viral meningitis
0.000 0.304 0.696
M05.8 Other seropositive rheumatoid arthritis
0.000 0.306 0.694
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.306 0.694
M05.2 Rheumatoid vasculitis
0.000 0.306 0.694
M05.1 Rheumatoid lung disease
0.000 0.306 0.694
M05.0 Felty's syndrome
0.000 0.306 0.694
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.308 0.692
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.308 0.692
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.308 0.692
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.308 0.692
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.308 0.692
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.308 0.692
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.308 0.692
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.308 0.692
J45.0 Predominantly allergic asthma
0.000 0.308 0.692
D51.8 Other vitamin B12 deficiency anaemias
0.000 0.309 0.690
D51.3 Other dietary vitamin B12 deficiency anaemia
0.000 0.309 0.690
D51.2 Transcobalamin II deficiency
0.000 0.309 0.690
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria
0.000 0.309 0.690
B90-B94 Sequelae of infectious and parasitic diseases
0.000 0.309 0.691
A60 Anogenital herpesviral [herpes simplex] infections
0.000 0.311 0.689
A59 Trichomoniasis
0.000 0.311 0.689
A56 Other sexually transmitted chlamydial diseases
0.000 0.311 0.689
A54 Gonococcal infection
0.000 0.311 0.689
A53 Other and unspecified syphilis
0.000 0.311 0.689
A52 Late syphilis
0.000 0.311 0.689
A51 Early syphilis
0.000 0.311 0.689
A50 Congenital syphilis
0.000 0.311 0.689
A64 Unspecified sexually transmitted disease
0.000 0.311 0.689
A58 Granuloma inguinale
0.000 0.311 0.689
A57 Chancroid
0.000 0.311 0.689
A55 Chlamydial lymphogranuloma (venereum)
0.000 0.311 0.689
B25-B34 Other viral diseases
0.000 0.311 0.689
C84 Peripheral and cutaneous T-cell lymphomas
0.000 0.312 0.688
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.000 0.316 0.684
C85.0 Lymphosarcoma
0.000 0.316 0.684
G81.9 Hemiplegia, unspecified
0.000 0.317 0.683
C88 Malignant immunoproliferative diseases
0.000 0.318 0.682
K36 Other appendicitis
0.000 0.318 0.682
D72 Other disorders of white blood cells
0.000 0.318 0.682
D61 Other aplastic anaemias
0.000 0.318 0.682
B99-B99 Other infectious diseases
0.000 0.319 0.681
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.000 0.320 0.680
D70 Agranulocytosis
0.000 0.321 0.679
J37 Chronic laryngitis and laryngotracheitis
0.000 0.323 0.676
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.324 0.676
A63.8 Other specified predominantly sexually transmitted diseases
0.000 0.325 0.675
G63.2 Diabetic polyneuropathy
0.000 0.326 0.674
G73 Disorders of myoneural junction and muscle in diseases classified elsewhere
0.000 0.326 0.674
G71 Primary disorders of muscles
0.000 0.326 0.674
D02 Carcinoma in situ of middle ear and respiratory system
0.000 0.327 0.673
E10.8 With unspecified complications
0.000 0.328 0.672
C44.0 Skin of lip
0.000 0.328 0.672
B37.4 Candidiasis of other urogenital sites
0.000 0.331 0.669
C09.8 Overlapping lesion of tonsil
0.000 0.332 0.668
C09.1 Tonsillar pillar (anterior) (posterior)
0.000 0.332 0.668
C09.0 Tonsillar fossa
0.000 0.332 0.668
B48 Other mycoses, not elsewhere classified
0.000 0.332 0.667
B47 Mycetoma
0.000 0.332 0.667
B46 Zygomycosis
0.000 0.332 0.667
B45 Cryptococcosis
0.000 0.332 0.667
B43 Chromomycosis and phaeomycotic abscess
0.000 0.332 0.667
B42 Sporotrichosis
0.000 0.332 0.667
B41 Paracoccidioidomycosis
0.000 0.332 0.667
B40 Blastomycosis
0.000 0.332 0.667
B39 Histoplasmosis
0.000 0.332 0.667
B38 Coccidioidomycosis
0.000 0.332 0.667
C83.8 Other types of diffuse non-Hodgkin's lymphoma
0.000 0.333 0.667
G72.9 Myopathy, unspecified
0.000 0.333 0.667
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.334 0.666
J20-J22 Other acute lower respiratory infections
0.000 0.335 0.665
J32.9 Chronic sinusitis, unspecified
0.000 0.336 0.664
D09 Carcinoma in situ of other and unspecified sites
0.000 0.337 0.663
M12 Other specific arthropathies
0.000 0.337 0.663
K35.3 Acute appendicitis with localized peritonitis
0.000 0.338 0.662
E16.2 Hypoglycaemia, unspecified
0.000 0.339 0.661
K35.0 Acute appendicitis with generalised peritonitis
0.000 0.340 0.660
C83.0 Small cell (diffuse)
0.000 0.342 0.658
D64.8 Other specified anaemias
0.000 0.342 0.657
G60 Hereditary and idiopathic neuropathy
0.000 0.345 0.655
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx
0.000 0.346 0.654
J96 Respiratory failure, not elsewhere classified
0.000 0.347 0.653
B36 Other superficial mycoses
0.000 0.349 0.651
E11.1 With ketoacidosis
0.000 0.350 0.650
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified
0.000 0.350 0.650
C83.6 Undifferentiated (diffuse)
0.000 0.350 0.650
C83.5 Lymphoblastic (diffuse)
0.000 0.350 0.650
C83.4 Immunoblastic (diffuse)
0.000 0.350 0.650
C83.2 Mixed small and large cell (diffuse)
0.000 0.350 0.650
B44.1 Other pulmonary aspergillosis
0.000 0.351 0.649
J82 Pulmonary eosinophilia, not elsewhere classified
0.000 0.351 0.649
B08 Other viral infections characterised by skin and mucous membrane lesions, not elsewhere classified
0.000 0.352 0.648
C05 Malignant neoplasm of palate
0.000 0.353 0.647
C83.1 Small cleaved cell (diffuse)
0.000 0.354 0.646
J44 Other chronic obstructive pulmonary disease
0.000 0.354 0.646
B01 Varicella [chickenpox]
0.000 0.355 0.645
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.000 0.358 0.641
C81 Hodgkin's disease
0.000 0.359 0.640
B37.7 Candidal septicaemia
0.000 0.362 0.638
B37.6 Candidal endocarditis
0.000 0.362 0.638
B37.5 Candidal meningitis
0.000 0.362 0.638
B37.2 Candidiasis of skin and nail
0.000 0.362 0.638
E11.2 With renal complications
0.000 0.362 0.638
C02.1 Border of tongue
0.000 0.362 0.638
A65-A69 Other spirochaetal diseases
0.000 0.363 0.637
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters
0.000 0.364 0.636
K35.1 Acute appendicitis with peritoneal abscess
0.000 0.364 0.636
C91 Lymphoid leukaemia
0.000 0.366 0.634
A49 Bacterial infection of unspecified site
0.000 0.369 0.631
K90.8 Other intestinal malabsorption
0.000 0.369 0.630
K90.3 Pancreatic steatorrhoea
0.000 0.369 0.630
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.369 0.630
K90.1 Tropical sprue
0.000 0.369 0.630
B06 Rubella [German measles]
0.000 0.370 0.630
B05 Measles
0.000 0.370 0.630
B09 Unspecified viral infection characterised by skin and mucous membrane lesions
0.000 0.370 0.630
B04 Monkeypox
0.000 0.370 0.630
B03 Smallpox
0.000 0.370 0.630
G37.5 Concentric sclerosis [Balo]
0.000 0.371 0.629
G37.4 Subacute necrotising myelitis
0.000 0.371 0.629
G37.2 Central pontine myelinolysis
0.000 0.371 0.629
G37.1 Central demyelination of corpus callosum
0.000 0.371 0.629
G37.0 Diffuse sclerosis
0.000 0.371 0.629
B65-B83 Helminthiases
0.000 0.373 0.627
J05 Acute obstructive laryngitis [croup] and epiglottitis
0.000 0.373 0.627
J95.9 Postprocedural respiratory disorder, unspecified
0.000 0.375 0.625
J95.5 Postprocedural subglottic stenosis
0.000 0.375 0.625
J95.4 Mendelson's syndrome
0.000 0.375 0.625
J95.3 Chronic pulmonary insufficiency following surgery
0.000 0.375 0.625
J95.2 Acute pulmonary insufficiency following nonthoracic surgery
0.000 0.375 0.625
J95.1 Acute pulmonary insufficiency following thoracic surgery
0.000 0.375 0.625
G70.9 Myoneural disorder, unspecified
0.000 0.375 0.625
G70.8 Other specified myoneural disorders
0.000 0.375 0.625
G70.2 Congenital and developmental myasthenia
0.000 0.375 0.625
G70.1 Toxic myoneural disorders
0.000 0.375 0.625
C44.7 Skin of lower limb, including hip
0.000 0.376 0.624
J84.9 Interstitial pulmonary disease, unspecified
0.000 0.380 0.619
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.381 0.618
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.381 0.618
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.000 0.381 0.618
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.381 0.618
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.381 0.618
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.381 0.618
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.381 0.618
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.381 0.618
E06.5 Other chronic thyroiditis
0.000 0.383 0.617
E06.4 Drug-induced thyroiditis
0.000 0.383 0.617
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.383 0.617
E06.1 Subacute thyroiditis
0.000 0.383 0.617
E06.0 Acute thyroiditis
0.000 0.383 0.617
A87.9 Viral meningitis, unspecified
0.000 0.384 0.616
J99.8 Respiratory disorders in other diseases classified elsewhere
0.000 0.385 0.615
G83 Other paralytic syndromes
0.000 0.385 0.615
B35 Dermatophytosis
0.000 0.386 0.614
K35.8 Acute appendicitis, other and unspecified
0.000 0.387 0.613
E40-E46 Malnutrition
0.000 0.388 0.612
B24 Unspecified human immunodeficiency virus [HIV] disease
0.000 0.388 0.612
J36 Peritonsillar abscess
0.000 0.390 0.610
D63.1 Anaemia in other chronic diseases classified elsewhere
0.000 0.391 0.609
E15 Nondiabetic hypoglycaemic coma
0.000 0.392 0.608
E03.8 Other specified hypothyroidism
0.000 0.394 0.606
G80 Infantile cerebral palsy
0.000 0.394 0.606
C85.7 Other specified types of non-Hodgkin's lymphoma
0.000 0.395 0.605
U80 Agent resistant to penicillin and related antibiotics
0.000 0.396 0.604
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.000 0.396 0.604
D55-D59 Haemolytic anaemias
0.000 0.396 0.604
C02.8 Overlapping lesion of tongue
0.000 0.401 0.599
C02.4 Lingual tonsil
0.000 0.401 0.599
C02.3 Anterior two-thirds of tongue, part unspecified
0.000 0.401 0.599
C02.2 Ventral surface of tongue
0.000 0.401 0.599
C02.0 Dorsal surface of tongue
0.000 0.401 0.599
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.401 0.599
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.403 0.597
E63 Other nutritional deficiencies
0.000 0.403 0.597
E56 Other vitamin deficiencies
0.000 0.403 0.597
E51 Thiamine deficiency
0.000 0.403 0.597
E50 Vitamin A deficiency
0.000 0.403 0.597
E60 Dietary zinc deficiency
0.000 0.403 0.597
E59 Dietary selenium deficiency
0.000 0.403 0.597
E58 Dietary calcium deficiency
0.000 0.403 0.597
E54 Ascorbic acid deficiency
0.000 0.403 0.597
E52 Niacin deficiency [pellagra]
0.000 0.403 0.597
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.000 0.404 0.596
B49 Unspecified mycosis
0.000 0.408 0.592
D05.1 Intraductal carcinoma in situ
0.000 0.409 0.591
G37.8 Other specified demyelinating diseases of central nervous system
0.000 0.411 0.589
K37 Unspecified appendicitis
0.000 0.411 0.589
J69 Pneumonitis due to solids and liquids
0.000 0.411 0.589
D52.9 Folate deficiency anaemia, unspecified
0.000 0.411 0.588
D04.5 Skin of trunk
0.000 0.412 0.587
J44.8 Other specified chronic obstructive pulmonary disease
0.000 0.413 0.587
D74 Methaemoglobinaemia
0.000 0.413 0.587
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.000 0.413 0.587
D71 Functional disorders of polymorphonuclear neutrophils
0.000 0.413 0.587
G64 Other disorders of peripheral nervous system
0.000 0.413 0.587
G00-G09 Inflammatory diseases of the central nervous system
0.000 0.413 0.586
M06.34 Rheumatoid nodule (Hand)
0.000 0.414 0.586
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters
0.000 0.415 0.585
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.000 0.415 0.585
E14.8 With unspecified complications
0.000 0.415 0.585
E14.7 With multiple complications
0.000 0.415 0.585
E14.6 With other specified complications
0.000 0.415 0.585
E14.5 With peripheral circulatory complications
0.000 0.415 0.585
E14.4 With neurological complications
0.000 0.415 0.585
E14.2 Withrenal complications
0.000 0.415 0.585
E14.1 With ketoacidosis
0.000 0.415 0.585
E14.0 With coma
0.000 0.415 0.585
D63.8 Anaemia in other chronic diseases classified elsewhere
0.000 0.415 0.584
D05.0 Lobular carcinoma in situ
0.000 0.416 0.584
J33.1 Polypoid sinus degeneration
0.000 0.417 0.583
B00.9 Herpesviral infection, unspecified
0.000 0.418 0.582
D62 Acute posthaemorrhagic anaemia
0.000 0.420 0.580
A88 Other viral infections of central nervous system, not elsewhere classified
0.000 0.421 0.579
A85 Other viral encephalitis, not elsewhere classified
0.000 0.421 0.579
A84 Tick-borne viral encephalitis
0.000 0.421 0.579
A83 Mosquito-borne viral encephalitis
0.000 0.421 0.579
A82 Rabies
0.000 0.421 0.579
A81 Atypical virus infections of central nervous system
0.000 0.421 0.579
A80 Acute poliomyelitis
0.000 0.421 0.579
A91 Dengue haemorrhagic fever
0.000 0.421 0.579
A90 Dengue fever [classical dengue]
0.000 0.421 0.579
A89 Unspecified viral infection of central nervous system
0.000 0.421 0.579
A48 Other bacterial diseases, not elsewhere classified
0.000 0.423 0.577
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters
0.000 0.423 0.577
M11.2 Other chondrocalcinosis
0.000 0.423 0.577
C10.9 Oropharynx, unspecified
0.000 0.424 0.576
E06.9 Thyroiditis, unspecified
0.000 0.426 0.574
D75 Other diseases of blood and blood-forming organs
0.000 0.426 0.574
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.428 0.571
M07 Psoriatic and enteropathic arthropathies
0.000 0.429 0.571
B37.9 Candidiasis, unspecified
0.000 0.429 0.571
J09-J18 Influenza and pneumonia
0.000 0.429 0.571
A40 Streptococcal septicaemia
0.000 0.429 0.570
E55 Vitamin D deficiency
0.000 0.430 0.570
C92.0 Acute myeloid leukaemia
0.000 0.430 0.570
E13.9 Without complications
0.000 0.431 0.569
E07.1 Dyshormogenetic goitre
0.000 0.431 0.569
E07.0 Hypersecretion of calcitonin
0.000 0.431 0.569
K38 Other diseases of appendix
0.000 0.434 0.566
D04.3 Skin of other and unspecified parts of face
0.000 0.437 0.563
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.000 0.438 0.562
G72.8 Other specified myopathies
0.000 0.440 0.560
G72.4 Inflammatory myopathy, not elsewhere classified
0.000 0.440 0.560
G72.3 Periodic paralysis
0.000 0.440 0.560
G72.2 Myopathy due to other toxic agents
0.000 0.440 0.560
G72.1 Alcoholic myopathy
0.000 0.440 0.560
G72.0 Drug-induced myopathy
0.000 0.440 0.560
J32.4 Chronic pansinusitis
0.000 0.440 0.560
B37.1 Pulmonary candidiasis
0.000 0.441 0.559
C51-C58 Malignant neoplasms of female genital organs
0.000 0.441 0.559
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters
0.000 0.441 0.559
J84.0 Alveolar and parietoalveolar conditions
0.000 0.442 0.558
B50-B64 Protozoal diseases
0.001 0.443 0.557
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.000 0.446 0.554
B23 Human immunodeficiency virus [HIV] disease resulting in other conditions
0.000 0.448 0.552
B22 Human immunodeficiency virus [HIV] disease resulting in other specified diseases
0.000 0.448 0.552
B21 Human immunodeficiency virus [HIV] disease resulting in malignant neoplasms
0.000 0.448 0.552
B20 Human immunodeficiency virus [HIV] disease resulting in infectious and parasitic diseases
0.000 0.448 0.552
C60-C63 Malignant neoplasms of male genital organs
0.000 0.449 0.551
J30 Vasomotor and allergic rhinitis
0.000 0.449 0.551
M10.9 Gout, unspecified
0.000 0.451 0.549
B44.8 Other forms of aspergillosis
0.000 0.451 0.549
B44.7 Disseminated aspergillosis
0.000 0.451 0.549
B44.2 Tonsillar aspergillosis
0.000 0.451 0.549
B44.0 Invasive pulmonary aspergillosis
0.000 0.451 0.549

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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