TreeWAS – Variant ID: rs11655550

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Showing all nodes without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.000	0.860	0.140
I74 Arterial embolism and thrombosis	0.000	0.868	0.132
I70-I79 Diseases of arteries, arterioles and capillaries	0.000	0.876	0.124
I77 Other disorders of arteries and arterioles	0.000	0.882	0.118
I77.1 Stricture of artery	0.000	0.886	0.114
I72 Other aneurysm	0.000	0.888	0.112
I27 Other pulmonary heart diseases	0.000	0.895	0.105
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.000	0.896	0.104
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.000	0.896	0.104
I07.1 Tricuspid insufficiency	0.000	0.898	0.102
I74.9 Embolism and thrombosis of unspecified artery	0.000	0.899	0.101
I72.4 Aneurysm of artery of lower extremity	0.000	0.900	0.100
I27.2 Other secondary pulmonary hypertension	0.000	0.900	0.100
I60-I69 Cerebrovascular diseases	0.000	0.900	0.100
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.000	0.900	0.099
I07 Rheumatic tricuspid valve diseases	0.000	0.901	0.099
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.000	0.901	0.099
Chapter IX Diseases of the circulatory system	0.000	0.901	0.099
I05-I09 Chronic rheumatic heart diseases	0.000	0.902	0.098
I27.8 Other specified pulmonary heart diseases	0.000	0.903	0.097
I60 Subarachnoid haemorrhage	0.000	0.903	0.097
I77.0 Arteriovenous fistula, acquired	0.000	0.905	0.095
I27.9 Pulmonary heart disease, unspecified	0.000	0.905	0.095
I64 Stroke, not specified as haemorrhage or infarction	0.000	0.906	0.094
I74.0 Embolism and thrombosis of abdominal aorta	0.000	0.907	0.093
I60.3 Subarachnoid haemorrhage from posterior communicating artery	0.000	0.907	0.093
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.000	0.907	0.092
I69 Sequelae of cerebrovascular disease	0.000	0.908	0.092
I78 Diseases of capillaries	0.000	0.909	0.090
I60.1 Subarachnoid haemorrhage from middle cerebral artery	0.000	0.910	0.090
I74.8 Embolism and thrombosis of other arteries	0.000	0.910	0.090
I72.3 Aneurysm of iliac artery	0.000	0.910	0.090
I77.2 Rupture of artery	0.000	0.911	0.089
I77.9 Disorder of arteries and arterioles, unspecified	0.000	0.912	0.088
I69.0 Sequelae of subarachnoid haemorrhage	0.000	0.913	0.087
I73 Other peripheral vascular diseases	0.000	0.914	0.086
I74.5 Embolism and thrombosis of iliac artery	0.000	0.915	0.085
I72.2 Aneurysm of renal artery	0.000	0.915	0.085
I77.5 Necrosis of artery	0.000	0.915	0.084
I77.4 Coeliac artery compression syndrome	0.000	0.915	0.084
I77.3 Arterial fibromuscular dysplasia	0.000	0.915	0.084
I69.1 Sequelae of intracerebral haemorrhage	0.000	0.917	0.083
I72.9 Aneurysm of unspecified site	0.000	0.918	0.082
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.000	0.919	0.081
I72.6 Aneurysm and dissection of vertebral artery	0.000	0.920	0.080
I72.5 Aneurysm and dissection of other precerebral arteries	0.000	0.920	0.080
I72.1 Aneurysm of artery of upper extremity	0.000	0.920	0.080
I09 Other rheumatic heart diseases	0.000	0.920	0.080
I72.0 Aneurysm of carotid artery	0.000	0.923	0.077
I72.8 Aneurysm of other specified arteries	0.000	0.923	0.077
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.000	0.923	0.077
I77.6 Arteritis, unspecified	0.000	0.923	0.077
I73.8 Other specified peripheral vascular diseases	0.000	0.923	0.077
I27.0 Primary pulmonary hypertension	0.000	0.924	0.076
I27.1 Kyphoscoliotic heart disease	0.000	0.924	0.075
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified	0.000	0.925	0.075
I78.0 Hereditary haemorrhagic telangiectasia	0.000	0.925	0.075
I28 Other diseases of pulmonary vessels	0.000	0.926	0.074
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.000	0.927	0.073
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.000	0.928	0.071
I07.9 Tricuspid valve disease, unspecified	0.000	0.929	0.071
I07.8 Other tricuspid valve diseases	0.000	0.929	0.071
I07.2 Tricuspid stenosis with insufficiency	0.000	0.929	0.071
I07.0 Tricuspid stenosis	0.000	0.929	0.071
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.000	0.929	0.071
I79.1 Aortitis in diseases classified elsewhere	0.000	0.929	0.071
I79.0 Aneurysm of aorta in diseases classified elsewhere	0.000	0.929	0.071
I60.2 Subarachnoid haemorrhage from anterior communicating artery	0.000	0.930	0.070
I60.5 Subarachnoid haemorrhage from vertebral artery	0.000	0.930	0.070
I60.9 Subarachnoid haemorrhage, unspecified	0.000	0.931	0.069
I65.2 Occlusion and stenosis of carotid artery	0.000	0.931	0.069
I00-I02 Acute rheumatic fever	0.000	0.931	0.069
I60.6 Subarachnoid haemorrhage from other intracranial arteries	0.000	0.932	0.068
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation	0.000	0.932	0.068
I09.9 Rheumatic heart disease, unspecified	0.000	0.933	0.067
I73.9 Peripheral vascular disease, unspecified	0.000	0.934	0.066
I78.8 Other diseases of capillaries	0.000	0.934	0.066
I08 Multiple valve diseases	0.000	0.934	0.066
I68 Cerebrovascular disorders in diseases classified elsewhere	0.000	0.934	0.066
I06 Rheumatic aortic valve diseases	0.000	0.935	0.065
I78.9 Disease of capillaries, unspecified	0.000	0.935	0.065
I77.8 Other specified disorders of arteries and arterioles	0.000	0.937	0.063
I05 Rheumatic mitral valve diseases	0.000	0.938	0.062
I08.0 Disorders of both mitral and aortic valves	0.000	0.940	0.060
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.000	0.941	0.059
I60.4 Subarachnoid haemorrhage from basilar artery	0.000	0.941	0.059
I09.8 Other specified rheumatic heart diseases	0.000	0.942	0.057
I09.2 Chronic rheumatic pericarditis	0.000	0.942	0.057
I09.1 Rheumatic diseases of endocardium, valve unspecified	0.000	0.942	0.057
I09.0 Rheumatic myocarditis	0.000	0.942	0.057
I63 Cerebral infarction	0.000	0.943	0.057
I61 Intracerebral haemorrhage	0.000	0.943	0.057
I62 Other nontraumatic intracranial haemorrhage	0.000	0.943	0.057
I73.1 Thromboangiitis obliterans [Buerger]	0.000	0.944	0.056
I28.8 Other specified diseases of pulmonary vessels	0.000	0.944	0.056
I65.9 Occlusion and stenosis of unspecified precerebral artery	0.000	0.945	0.055
I65.8 Occlusion and stenosis of other precerebral artery	0.000	0.945	0.055
I05.9 Mitral valve disease, unspecified	0.000	0.946	0.054
I70 Atherosclerosis	0.000	0.946	0.053
I66.9 Occlusion and stenosis of unspecified cerebral artery	0.000	0.947	0.053
I28.9 Disease of pulmonary vessels, unspecified	0.000	0.947	0.053
I28.1 Aneurysm of pulmonary artery	0.000	0.947	0.053
I28.0 Arteriovenous fistula of pulmonary vessels	0.000	0.947	0.053
S92.00 Fracture of calcaneus (closed)	0.000	0.947	0.053
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries	0.000	0.947	0.052
I60.8 Other subarachnoid haemorrhage	0.000	0.947	0.052
I66.8 Occlusion and stenosis of other cerebral artery	0.000	0.948	0.052
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries	0.000	0.948	0.052
I66.3 Occlusion and stenosis of cerebellar arteries	0.000	0.948	0.052
I66.2 Occlusion and stenosis of posterior cerebral artery	0.000	0.948	0.052
I66.1 Occlusion and stenosis of anterior cerebral artery	0.000	0.948	0.052
I66.0 Occlusion and stenosis of middle cerebral artery	0.000	0.948	0.052
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.000	0.948	0.052
I69.3 Sequelae of cerebral infarction	0.000	0.950	0.050
I78.1 Naevus, nonneoplastic	0.000	0.950	0.050
I02 Rheumatic chorea	0.000	0.950	0.050
I01 Rheumatic fever with heart involvement	0.000	0.950	0.050
S92.0 Fracture of calcaneus	0.000	0.951	0.049
I67 Other cerebrovascular diseases	0.000	0.952	0.048
I65.1 Occlusion and stenosis of basilar artery	0.000	0.952	0.048
I65.0 Occlusion and stenosis of vertebral artery	0.000	0.952	0.047
I00 Rheumatic fever without mention of heart involvement	0.000	0.952	0.047
I08.9 Multiple valve disease, unspecified	0.000	0.953	0.047
I68.8 Other cerebrovascular disorders in diseases classified elsewhere	0.000	0.953	0.047
I68.2 Cerebral arteritis in other diseases classified elsewhere	0.000	0.953	0.047
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere	0.000	0.953	0.047
I61.8 Other intracerebral haemorrhage	0.000	0.953	0.047
I06.9 Rheumatic aortic valve disease, unspecified	0.000	0.953	0.047
I06.8 Other rheumatic aortic valve diseases	0.000	0.953	0.047
I06.2 Rheumatic aortic stenosis with insufficiency	0.000	0.953	0.047
I06.1 Rheumatic aortic insufficiency	0.000	0.953	0.047
I61.2 Intracerebral haemorrhage in hemisphere, unspecified	0.000	0.953	0.047
S92 Fracture of foot, except ankle	0.000	0.953	0.047
I71 Aortic aneurysm and dissection	0.000	0.953	0.046
I61.0 Intracerebral haemorrhage in hemisphere, subcortical	0.000	0.955	0.045
I05.8 Other mitral valve diseases	0.000	0.955	0.045
I08.8 Other multiple valve diseases	0.000	0.955	0.045
I26 Pulmonary embolism	0.000	0.957	0.043
I63.0 Cerebral infarction due to thrombosis of precerebral arteries	0.000	0.957	0.043
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.000	0.957	0.043
I67.2 Cerebral atherosclerosis	0.000	0.957	0.043
I08.2 Disorders of both aortic and tricuspid valves	0.000	0.958	0.042
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.000	0.958	0.042
I06.0 Rheumatic aortic stenosis	0.000	0.958	0.042
I61.4 Intracerebral haemorrhage in cerebellum	0.000	0.958	0.042
Q80-Q89 Other congenital malformations	0.042	0.958	0.000
I68.0 Cerebral amyloid angiopathy	0.000	0.958	0.041
S92.4 Fracture of great toe	0.000	0.958	0.041
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic	0.000	0.959	0.041
I63.1 Cerebral infarction due to embolism of precerebral arteries	0.000	0.959	0.041
I63.8 Other cerebral infarction	0.000	0.959	0.041
I62.1 Nontraumatic extradural haemorrhage	0.000	0.959	0.041
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.040	0.960	0.000
Q60-Q64 Congenital malformations of the urinary system	0.040	0.960	0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.000	0.961	0.039
Q61 Cystic kidney disease	0.039	0.961	0.000
Q87 Other specified congenital malformation syndromes affecting multiple systems	0.039	0.961	0.000
Q61.2 Polycystic kidney, adult type	0.039	0.961	0.000
S92.5 Fracture of other toe	0.000	0.961	0.039
I61.3 Intracerebral haemorrhage in brain stem	0.000	0.961	0.039
S92.2 Fracture of other tarsal bone(s)	0.000	0.961	0.039
I70.9 Generalised and unspecified atherosclerosis	0.000	0.961	0.038
I70.8 Atherosclerosis of other arteries	0.000	0.961	0.038
I61.6 Intracerebral haemorrhage, multiple localised	0.000	0.961	0.038
S90-S99 Injuries to the ankle and foot	0.000	0.962	0.038
S92.7 Multiple fractures of foot	0.000	0.962	0.038
I05.2 Mitral stenosis with insufficiency	0.000	0.962	0.038
Q89 Other congenital malformations, not elsewhere classified	0.037	0.963	0.000
I05.1 Rheumatic mitral insufficiency	0.000	0.963	0.037
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.037	0.963	0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.000	0.963	0.037
S91 Open wound of ankle and foot	0.000	0.964	0.036
I01.9 Acute rheumatic heart disease, unspecified	0.000	0.964	0.036
I01.8 Other acute rheumatic heart disease	0.000	0.964	0.036
I01.2 Acute rheumatic myocarditis	0.000	0.964	0.036
I01.1 Acute rheumatic endocarditis	0.000	0.964	0.036
I01.0 Acute rheumatic pericarditis	0.000	0.964	0.036
I02.9 Rheumatic chorea without heart involvement	0.000	0.964	0.036
I02.0 Rheumatic chorea with heart involvement	0.000	0.964	0.036
Q38-Q45 Other congenital malformations of the digestive system	0.036	0.964	0.000
S92.40 Fracture of great toe (closed)	0.000	0.964	0.036
S92.01 Fracture of calcaneus (open)	0.000	0.964	0.036
I05.0 Mitral stenosis	0.000	0.964	0.035
I62.0 Subdural haemorrhage (acute) (nontraumatic)	0.000	0.965	0.035
Q85 Phakomatoses, not elsewhere classified	0.035	0.965	0.000
I67.7 Cerebral arteritis, not elsewhere classified	0.000	0.965	0.035
I67.6 Nonpyogenic thrombosis of intracranial venous system	0.000	0.965	0.035
I67.5 Moyamoya disease	0.000	0.965	0.035
I67.4 Hypertensive encephalopathy	0.000	0.965	0.035
I67.3 Progressive vascular leukoencephalopathy	0.000	0.965	0.035
I61.1 Intracerebral haemorrhage in hemisphere, cortical	0.000	0.965	0.035
I71.3 Abdominal aortic aneurysm, ruptured	0.000	0.965	0.035
I63.4 Cerebral infarction due to embolism of cerebral arteries	0.000	0.965	0.034
Q87.8 Other specified congenital malformation syndromes, not elsewhere classified	0.034	0.966	0.000
I71.0 Dissection of aorta [any part]	0.000	0.966	0.034
Q89.2 Congenital malformations of other endocrine glands	0.034	0.966	0.000
I67.9 Cerebrovascular disease, unspecified	0.000	0.966	0.034
S92.9 Fracture of foot, unspecified	0.000	0.966	0.034
Q63 Other congenital malformations of kidney	0.034	0.966	0.000
Q61.3 Polycystic kidney, unspecified	0.034	0.966	0.000
I62.9 Intracranial haemorrhage (nontraumatic), unspecified	0.000	0.966	0.034
I71.8 Aortic aneurysm of unspecified site, ruptured	0.000	0.966	0.033
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.000	0.966	0.033
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.000	0.966	0.033
I71.1 Thoracic aortic aneurysm, ruptured	0.000	0.966	0.033
S91.1 Open wound of toe(s) without damage to nail	0.000	0.966	0.033
S92.41 Fracture of great toe (open)	0.000	0.967	0.033
S92.50 Fracture of other toe (closed)	0.000	0.967	0.033
Q87.4 Marfan's syndrome	0.033	0.967	0.000
S92.20 Fracture of other tarsal bone(s) (closed)	0.000	0.967	0.033
I70.0 Atherosclerosis of aorta	0.000	0.967	0.032
Q00-Q07 Congenital malformations of the nervous system	0.033	0.967	0.000
Q85.0 Neurofibromatosis (nonmalignant)	0.033	0.967	0.000
I08.1 Disorders of both mitral and tricuspid valves	0.000	0.968	0.032
I70.2 Atherosclerosis of arteries of the extremities	0.000	0.968	0.032
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.000	0.968	0.032
Q66 Congenital deformities of feet	0.032	0.968	0.000
S92.70 Multiple fractures of foot (closed)	0.000	0.969	0.031
Q87.2 Congenital malformation syndromes predominantly involving limbs	0.031	0.969	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.031	0.969	0.000
I61.5 Intracerebral haemorrhage, intraventricular	0.000	0.969	0.031
I67.0 Dissection of cerebral arteries, nonruptured	0.000	0.969	0.031
Q82 Other congenital malformations of skin	0.031	0.969	0.000
Q35-Q37 Cleft lip and cleft palate	0.031	0.969	0.000
S92.1 Fracture of talus	0.000	0.969	0.030
I26.0 Pulmonary embolism with mention of acute cor pulmonale	0.000	0.970	0.030
S91.3 Open wound of other parts of foot	0.000	0.970	0.030
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.030	0.970	0.000
Q60 Renal agenesis and other reduction defects of kidney	0.030	0.970	0.000
Q83 Congenital malformations of breast	0.030	0.970	0.000
Q86 Congenital malformation syndromes due to known exogenous causes, not elsewhere classified	0.030	0.970	0.000
Q84 Other congenital malformations of integument	0.030	0.970	0.000
Q81 Epidermolysis bullosa	0.030	0.970	0.000
Q80 Congenital ichthyosis	0.030	0.970	0.000
Q39 Congenital malformations of oesophagus	0.030	0.970	0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter	0.030	0.970	0.000
Q40 Other congenital malformations of upper alimentary tract	0.029	0.971	0.000
Q63.0 Accessory kidney	0.029	0.971	0.000
Q87.0 Congenital malformation syndromes predominantly affecting facial appearance	0.029	0.971	0.000
S90 Superficial injury of ankle and foot	0.000	0.971	0.029
Q30-Q34 Congenital malformations of the respiratory system	0.029	0.971	0.000
I70.1 Atherosclerosis of renal artery	0.001	0.971	0.028
Q07 Other congenital malformations of nervous system	0.029	0.971	0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver	0.028	0.971	0.000
Q61.9 Cystic kidney disease, unspecified	0.028	0.971	0.000
Q61.8 Other cystic kidney diseases	0.028	0.971	0.000
Q61.4 Renal dysplasia	0.028	0.971	0.000
Q61.1 Polycystic kidney, infantile type	0.028	0.971	0.000
Q87.5 Other congenital malformation syndromes with other skeletal changes	0.028	0.971	0.000
Q87.3 Congenital malformation syndromes involving early overgrowth	0.028	0.971	0.000
Q87.1 Congenital malformation syndromes predominantly associated with short stature	0.028	0.971	0.000
Q45 Other congenital malformations of digestive system	0.028	0.972	0.000
S96 Injury of muscle and tendon at ankle and foot level	0.000	0.972	0.028
S92.51 Fracture of other toe (open)	0.000	0.972	0.028
S92.21 Fracture of other tarsal bone(s) (open)	0.000	0.972	0.028
I70.81 Atherosclerosis of other arteries (with gangrene)	0.000	0.972	0.028
I70.80 Atherosclerosis of other arteries (without gangrene)	0.000	0.972	0.028
I70.91 Generalized and unspecified atherosclerosis (with gangrene)	0.000	0.972	0.028
I70.90 Generalized and unspecified atherosclerosis (without gangrene)	0.000	0.972	0.028
Q74 Other congenital malformations of limb(s)	0.028	0.972	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.028	0.972	0.000
Q76 Congenital malformations of spine and bony thorax	0.028	0.972	0.000
S98 Traumatic amputation of ankle and foot	0.000	0.972	0.027
S97 Crushing injury of ankle and foot	0.000	0.972	0.027
S95 Injury of blood vessels at ankle and foot level	0.000	0.972	0.027
S94 Injury of nerves at ankle and foot level	0.000	0.972	0.027
Q78 Other osteochondrodysplasias	0.027	0.972	0.000
S92.71 Multiple fractures of foot (open)	0.000	0.973	0.027
I63.3 Cerebral infarction due to thrombosis of cerebral arteries	0.000	0.973	0.027
Q61.5 Medullary cystic kidney	0.027	0.973	0.000
Q89.9 Congenital malformation, unspecified	0.027	0.973	0.000
Q89.8 Other specified congenital malformations	0.027	0.973	0.000
Q89.7 Multiple congenital malformations, not elsewhere classified	0.027	0.973	0.000
Q89.4 Conjoined twins	0.027	0.973	0.000
Q89.3 Situs inversus	0.027	0.973	0.000
Q89.1 Congenital malformations of adrenal gland	0.027	0.973	0.000
Q89.0 Congenital malformations of spleen	0.027	0.973	0.000
Q66.8 Other congenital deformities of feet	0.027	0.973	0.000
S92.3 Fracture of metatarsal bone	0.000	0.973	0.027
Q63.1 Lobulated, fused and horseshoe kidney	0.027	0.973	0.000
S90.9 Superficial injury of ankle and foot, unspecified	0.000	0.973	0.027
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine	0.026	0.973	0.000
Q75 Other congenital malformations of skull and face bones	0.026	0.973	0.000
Q73 Reduction defects of unspecified limb	0.026	0.973	0.000
Q72 Reduction defects of lower limb	0.026	0.973	0.000
Q71 Reduction defects of upper limb	0.026	0.973	0.000
Q70 Syndactyly	0.026	0.973	0.000
Q69 Polydactyly	0.026	0.973	0.000
Q68 Other congenital musculoskeletal deformities	0.026	0.973	0.000
S91.0 Open wound of ankle	0.000	0.974	0.026
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified	0.026	0.974	0.000
Q10 Congenital malformations of eyelid, lachrymal apparatus and orbit	0.026	0.974	0.000
S91.7 Multiple open wounds of ankle and foot	0.000	0.974	0.026
S91.2 Open wound of toe(s) with damage to nail	0.000	0.974	0.026
Q42 Congenital absence, atresia and stenosis of large intestine	0.026	0.974	0.000
Q41 Congenital absence, atresia and stenosis of small intestine	0.026	0.974	0.000
Q07.0 Arnold-Chiari syndrome	0.026	0.974	0.000
Q67.5 Congenital deformity of spine	0.026	0.974	0.000
Q04 Other congenital malformations of brain	0.025	0.974	0.000
Q85.1 Tuberous sclerosis	0.025	0.975	0.000
S93.0 Dislocation of ankle joint	0.000	0.975	0.025
S93.1 Dislocation of toe(s)	0.000	0.975	0.025
I10-I15 Hypertensive diseases	0.000	0.975	0.025
Q64 Other congenital malformations of urinary system	0.025	0.975	0.000
Q39.6 Diverticulum of oesophagus	0.025	0.975	0.000
Q40.3 Congenital malformation of stomach, unspecified	0.025	0.975	0.000
S92.91 Fracture of foot, unspecified (open)	0.000	0.975	0.024
S92.90 Fracture of foot, unspecified (closed)	0.000	0.975	0.024
Q63.9 Congenital malformation of kidney, unspecified	0.024	0.975	0.000
Q63.8 Other specified congenital malformations of kidney	0.024	0.975	0.000
Q63.3 Hyperplastic and giant kidney	0.024	0.975	0.000
Q65 Congenital deformities of hip	0.025	0.975	0.000
S93.3 Dislocation of other and unspecified parts of foot	0.000	0.975	0.025
Q82.5 Congenital nonneoplastic naevus	0.024	0.975	0.000
Q43 Other congenital malformations of intestine	0.024	0.975	0.000
I67.1 Cerebral aneurysm, nonruptured	0.000	0.976	0.024
Q66.3 Other congenital varus deformities of feet	0.024	0.976	0.000
Q60.2 Renal agenesis, unspecified	0.024	0.976	0.000
Q61.0 Congenital single renal cyst	0.024	0.976	0.000
Q37 Cleft palate with cleft lip	0.024	0.976	0.000
Q85.9 Phakomatosis, unspecified	0.024	0.976	0.000
I70.01 Atherosclerosis of aorta (with gangrene)	0.000	0.976	0.023
I63.9 Cerebral infarction, unspecified	0.000	0.976	0.024
Q39.4 Oesophageal web	0.024	0.976	0.000
Q06 Other congenital malformations of spinal cord	0.023	0.976	0.000
Q03 Congenital hydrocephalus	0.023	0.976	0.000
Q01 Encephalocele	0.023	0.976	0.000
Q00 Anencephaly and similar malformations	0.023	0.976	0.000
Q02 Microcephaly	0.023	0.976	0.000
Q66.7 Pes cavus	0.023	0.977	0.000
S96.1 Injury of muscle and tendon of long extensor muscle of toe at ankle and foot level	0.000	0.977	0.023
Q12 Congenital lens malformations	0.023	0.977	0.000
Q44.6 Cystic disease of liver	0.023	0.977	0.000
Q63.2 Ectopic kidney	0.023	0.977	0.000
S93.4 Sprain and strain of ankle	0.000	0.977	0.023
S93.6 Sprain and strain of other and unspecified parts of foot	0.000	0.977	0.023
S93.5 Sprain and strain of toe(s)	0.000	0.977	0.023
S93.2 Rupture of ligaments at ankle and foot level	0.000	0.977	0.023
Q38 Other congenital malformations of tongue, mouth and pharynx	0.023	0.977	0.000
Q45.3 Other congenital malformations of pancreas and pancreatic duct	0.023	0.977	0.000
Q66.9 Congenital deformity of feet, unspecified	0.023	0.977	0.000
Q66.6 Other congenital valgus deformities of feet	0.023	0.977	0.000
Q66.5 Congenital pes planus	0.023	0.977	0.000
Q66.4 Talipes calcaneovalgus	0.023	0.977	0.000
Q66.2 Metatarsus varus	0.023	0.977	0.000
Q66.1 Talipes calcaneovarus	0.023	0.977	0.000
Q66.0 Talipes equinovarus	0.023	0.977	0.000
Q10.0 Congenital ptosis	0.023	0.977	0.000
Q16 Congenital malformations of ear causing impairment of hearing	0.023	0.977	0.000
Q15 Other congenital malformations of eye	0.023	0.977	0.000
Q14 Congenital malformations of posterior segment of eye	0.023	0.977	0.000
Q13 Congenital malformations of anterior segment of eye	0.023	0.977	0.000
Q11 Anophthalmos, microphthalmos and macrophthalmos	0.023	0.977	0.000
Q76.5 Cervical rib	0.023	0.977	0.000
Q74.0 Other congenital malformations of upper limb(s), including shoulder girdle	0.022	0.977	0.000
Q82.9 Congenital malformation of skin, unspecified	0.022	0.977	0.000
Q82.4 Ectodermal dysplasia (anhidrotic)	0.022	0.977	0.000
Q82.3 Incontinentia pigmenti	0.022	0.977	0.000
Q82.2 Mastocytosis	0.022	0.977	0.000
Q82.1 Xeroderma pigmentosum	0.022	0.977	0.000
Q82.0 Hereditary lymphoedema	0.022	0.977	0.000
Q62.5 Duplication of ureter	0.022	0.977	0.000
Q36 Cleft lip	0.022	0.978	0.000
Q35 Cleft palate	0.022	0.978	0.000
S92.11 Fracture of talus (open)	0.000	0.978	0.022
S90.8 Other superficial injuries of ankle and foot	0.000	0.978	0.022
I11 Hypertensive heart disease	0.000	0.978	0.022
Q67.6 Pectus excavatum	0.022	0.978	0.000
Q67.8 Other congenital deformities of chest	0.022	0.978	0.000
Q67.7 Pectus carinatum	0.022	0.978	0.000
Q67.4 Other congenital deformities of skull, face and jaw	0.022	0.978	0.000
Q67.3 Plagiocephaly	0.022	0.978	0.000
Q67.2 Dolichocephaly	0.022	0.978	0.000
Q67.1 Compression facies	0.022	0.978	0.000
Q67.0 Facial asymmetry	0.022	0.978	0.000
Q60.6 Potter's syndrome	0.022	0.978	0.000
Q60.5 Renal hypoplasia, unspecified	0.022	0.978	0.000
Q60.4 Renal hypoplasia, bilateral	0.022	0.978	0.000
Q60.3 Renal hypoplasia, unilateral	0.022	0.978	0.000
Q60.1 Renal agenesis, bilateral	0.022	0.978	0.000
Q83.8 Other congenital malformations of breast	0.022	0.978	0.000
Q83.9 Congenital malformation of breast, unspecified	0.022	0.978	0.000
Q83.3 Accessory nipple	0.022	0.978	0.000
Q83.2 Absent nipple	0.022	0.978	0.000
Q83.1 Accessory breast	0.022	0.978	0.000
Q83.0 Congenital absence of breast with absent nipple	0.022	0.978	0.000
Q17 Other congenital malformations of ear	0.022	0.978	0.000
Q80.9 Congenital ichthyosis, unspecified	0.022	0.978	0.000
Q80.8 Other congenital ichthyosis	0.022	0.978	0.000
Q80.4 Harlequin foetus	0.022	0.978	0.000
Q80.3 Congenital bullous ichthyosiform erythroderma	0.022	0.978	0.000
Q80.2 Lamellar ichthyosis	0.022	0.978	0.000
Q80.1 X-linked ichthyosis	0.022	0.978	0.000
Q80.0 Ichthyosis vulgaris	0.022	0.978	0.000
Q81.9 Epidermolysis bullosa, unspecified	0.022	0.978	0.000
Q81.8 Other epidermolysis bullosa	0.022	0.978	0.000
Q81.2 Epidermolysis bullosa dystrophica	0.022	0.978	0.000
Q81.1 Epidermolysis bullosa letalis	0.022	0.978	0.000
Q81.0 Epidermolysis bullosa simplex	0.022	0.978	0.000
Q84.9 Congenital malformation of integument, unspecified	0.022	0.978	0.000
Q84.8 Other specified congenital malformations of integument	0.022	0.978	0.000
Q84.6 Other congenital malformations of nails	0.022	0.978	0.000
Q84.5 Enlarged and hypertrophic nails	0.022	0.978	0.000
Q84.4 Congenital leukonychia	0.022	0.978	0.000
Q84.3 Anonychia	0.022	0.978	0.000
Q84.2 Other congenital malformations of hair	0.022	0.978	0.000
Q84.1 Congenital morphological disturbances of hair, not elsewhere classified	0.022	0.978	0.000
Q84.0 Congenital alopecia	0.022	0.978	0.000
Q86.8 Other congenital malformation syndromes due to known exogenous causes	0.022	0.978	0.000
Q86.2 Dysmorphism due to warfarin	0.022	0.978	0.000
Q86.1 Foetal hydantoin syndrome	0.022	0.978	0.000
Q86.0 Foetal alcohol syndrome (dysmorphic)	0.022	0.978	0.000
Q39.9 Congenital malformation of oesophagus, unspecified	0.022	0.978	0.000
Q39.8 Other congenital malformations of oesophagus	0.022	0.978	0.000
Q39.5 Congenital dilatation of oesophagus	0.022	0.978	0.000
Q39.3 Congenital stenosis and stricture of oesophagus	0.022	0.978	0.000
Q39.2 Congenital tracheooesophageal fistula without atresia	0.022	0.978	0.000
Q39.1 Atresia of oesophagus with tracheooesophageal fistula	0.022	0.978	0.000
Q39.0 Atresia of oesophagus without fistula	0.022	0.978	0.000
S99 Other and unspecified injuries of ankle and foot	0.000	0.978	0.021
Q76.4 Other congenital malformations of spine, not associated with scoliosis	0.022	0.978	0.000
Q62.8 Other congenital malformations of ureter	0.021	0.978	0.000
Q62.7 Congenital vesico-uretero-renal reflux	0.021	0.978	0.000
Q62.6 Malposition of ureter	0.021	0.978	0.000
Q62.4 Agenesis of ureter	0.021	0.978	0.000
Q62.3 Other obstructive defects of renal pelvis and ureter	0.021	0.978	0.000
Q62.2 Congenital megaloureter	0.021	0.978	0.000
Q62.1 Atresia and stenosis of ureter	0.021	0.978	0.000
Q62.0 Congenital hydronephrosis	0.021	0.978	0.000
Q79.8 Other congenital malformations of musculoskeletal system	0.021	0.979	0.000
Q40.9 Congenital malformation of upper alimentary tract, unspecified	0.021	0.979	0.000
Q40.8 Other specified congenital malformations of upper alimentary tract	0.021	0.979	0.000
Q40.1 Congenital hiatus hernia	0.021	0.979	0.000
Q40.0 Congenital hypertrophic pyloric stenosis	0.021	0.979	0.000
Q40.2 Other specified congenital malformations of stomach	0.021	0.979	0.000
S90.7 Multiple superficial injuries of ankle and foot	0.000	0.979	0.021
S90.2 Contusion of toe(s) with damage to nail	0.000	0.979	0.021
S90.1 Contusion of toe(s) without damage to nail	0.000	0.979	0.021
Q34 Other congenital malformations of respiratory system	0.021	0.979	0.000
Q33 Congenital malformations of lung	0.021	0.979	0.000
Q32 Congenital malformations of trachea and bronchus	0.021	0.979	0.000
Q31 Congenital malformations of larynx	0.021	0.979	0.000
Q30 Congenital malformations of nose	0.021	0.979	0.000
Q85.8 Other phakomatoses, not elsewhere classified	0.021	0.979	0.000
I70.11 Atherosclerosis of renal artery (with gangrene)	0.001	0.979	0.020
Q82.8 Other specified congenital malformations of skin	0.021	0.979	0.000
Q78.0 Osteogenesis imperfecta	0.021	0.979	0.000
Q07.9 Congenital malformation of nervous system, unspecified	0.021	0.979	0.000
Q07.8 Other specified congenital malformations of nervous system	0.021	0.979	0.000
Q44.7 Other congenital malformations of liver	0.021	0.979	0.000
Q44.5 Other congenital malformations of bile ducts	0.021	0.979	0.000
Q44.4 Choledochal cyst	0.021	0.979	0.000
Q44.3 Congenital stenosis and stricture of bile ducts	0.021	0.979	0.000
Q44.2 Atresia of bile ducts	0.021	0.979	0.000
Q44.1 Other congenital malformations of gallbladder	0.021	0.979	0.000
Q44.0 Agenesis, aplasia and hypoplasia of gallbladder	0.021	0.979	0.000
Q74.2 Other congenital malformations of lower limb(s), including pelvic girdle	0.021	0.979	0.000
Q45.9 Congenital malformation of digestive system, unspecified	0.020	0.979	0.000
Q45.2 Congenital pancreatic cyst	0.020	0.979	0.000
Q45.1 Annular pancreas	0.020	0.979	0.000
Q45.0 Agenesis, aplasia and hypoplasia of pancreas	0.020	0.979	0.000
Q04.6 Congenital cerebral cysts	0.020	0.979	0.000
Q60.0 Renal agenesis, unilateral	0.020	0.979	0.000
S96.7 Injury of multiple muscles and tendons at ankle and foot level	0.000	0.979	0.020
S96.2 Injury of intrinsic muscle and tendon at ankle and foot level	0.000	0.979	0.020
S96.0 Injury of muscle and tendon of long flexor muscle of toe at ankle and foot level	0.000	0.979	0.020
Q45.8 Other specified congenital malformations of digestive system	0.020	0.980	0.000
Z98.0 Intestinal bypass and anastomosis status	0.000	0.980	0.020
Q18 Other congenital malformations of face and neck	0.020	0.980	0.000
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.000	0.980	0.020
S96.9 Injury of unspecified muscle and tendon at ankle and foot level	0.000	0.980	0.020
Q74.9 Unspecified congenital malformation of limb(s)	0.020	0.980	0.000
Q74.8 Other specified congenital malformations of limb(s)	0.020	0.980	0.000
Q74.3 Arthrogryposis multiplex congenita	0.020	0.980	0.000
Q99 Other chromosome abnormalities, not elsewhere classified	0.020	0.980	0.000
Q97 Other sex chromosome abnormalities, female phenotype, not elsewhere classified	0.020	0.980	0.000
Q95 Balanced rearrangements and structural markers, not elsewhere classified	0.020	0.980	0.000
Q93 Monosomies and deletions from the autosomes, not elsewhere classified	0.020	0.980	0.000
Q92 Other trisomies and partial trisomies of the autosomes, not elsewhere classified	0.020	0.980	0.000
Q91 Edwards' syndrome and Patau's syndrome	0.020	0.980	0.000
Q90 Down's syndrome	0.020	0.980	0.000
Q76.9 Congenital malformation of bony thorax, unspecified	0.020	0.980	0.000
Q76.8 Other congenital malformations of bony thorax	0.020	0.980	0.000
Q76.7 Congenital malformation of sternum	0.020	0.980	0.000
Q76.6 Other congenital malformations of ribs	0.020	0.980	0.000
Q76.3 Congenital scoliosis due to congenital bony malformation	0.020	0.980	0.000
Q76.2 Congenital spondylolisthesis	0.020	0.980	0.000
Q76.1 Klippel-Feil syndrome	0.020	0.980	0.000
I70.21 Atherosclerosis of arteries of extremities (with gangrene)	0.000	0.980	0.020
I73.0 Raynaud's syndrome	0.000	0.980	0.020
Q98 Other sex chromosome abnormalities, male phenotype, not elsewhere classified	0.020	0.980	0.000
S94.9 Injury of unspecified nerve at ankle and foot level	0.000	0.980	0.020
S94.8 Injury of other nerves at ankle and foot level	0.000	0.980	0.020
S94.7 Injury of multiple nerves at ankle and foot level	0.000	0.980	0.020
S94.3 Injury of cutaneous sensory nerve at ankle and foot level	0.000	0.980	0.020
S94.2 Injury of deep peroneal nerve at ankle and foot level	0.000	0.980	0.020
S94.1 Injury of medial plantar nerve	0.000	0.980	0.020
S94.0 Injury of lateral plantar nerve	0.000	0.980	0.020
S95.9 Injury of unspecified blood vessel at ankle and foot level	0.000	0.980	0.020
S95.8 Injury of other blood vessels at ankle and foot level	0.000	0.980	0.020

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations