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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs116571774
log Bayes Factor = 18.8021
Chromosome 6   position 32,594,612  (GRCh37) Explore rs116571774 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
J45.9 Asthma, unspecified
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.001 0.999
E00-E07 Disorders of thyroid gland
0.000 0.001 0.999
J45 Asthma
0.000 0.002 0.998
J40-J47 Chronic lower respiratory diseases
0.000 0.003 0.997
M06.9 Rheumatoid arthritis, unspecified
0.000 0.003 0.997
# Top node
0.000 0.003 0.996
K90 Intestinal malabsorption
0.000 0.004 0.996
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.004 0.996
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.004 0.996
Chapter X Diseases of the respiratory system
0.000 0.004 0.996
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.004 0.996
K90-K93 Other diseases of the digestive system
0.000 0.005 0.995
Chapter XI Diseases of the digestive system
0.000 0.005 0.995
Chapter II Neoplasms
0.000 0.006 0.994
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.000 0.009 0.991
C43-C44 Melanoma and other malignant neoplasms of skin
0.000 0.011 0.989
C44 Other malignant neoplasms of skin
0.000 0.011 0.989
K20-K31 Diseases of oesophagus, stomach and duodenum
0.000 0.018 0.982
C44.3 Skin of other and unspecified parts of face
0.000 0.019 0.981
D60-D64 Aplastic and other anaemias
0.000 0.022 0.978
K29 Gastritis and duodenitis
0.000 0.026 0.974
D64 Other anaemias
0.000 0.030 0.970
K29.8 Duodenitis
0.000 0.031 0.969
J44 Other chronic obstructive pulmonary disease
0.000 0.032 0.968
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.000 0.035 0.965
D64.9 Anaemia, unspecified
0.000 0.036 0.964
C44.7 Skin of lower limb, including hip
0.000 0.037 0.963
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.058 0.942
K20 Oesophagitis
0.000 0.070 0.930
J00-J06 Acute upper respiratory infections
0.000 0.072 0.928
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.000 0.101 0.899
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.000 0.103 0.896
J20-J22 Other acute lower respiratory infections
0.000 0.107 0.893
J44.8 Other specified chronic obstructive pulmonary disease
0.000 0.110 0.890
E05.9 Thyrotoxicosis, unspecified
0.000 0.110 0.890
J46 Status asthmaticus
0.000 0.114 0.886
M06 Other rheumatoid arthritis
0.018 0.117 0.865
K22 Other diseases of oesophagus
0.000 0.118 0.882
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.125 0.875
D00-D09 In situ neoplasms
0.000 0.126 0.874
D37-D48 Neoplasms of uncertain or unknown behaviour
0.000 0.127 0.873
K29.4 Chronic atrophic gastritis
0.000 0.133 0.867
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.000 0.134 0.866
J02 Acute pharyngitis
0.000 0.139 0.861
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.000 0.142 0.858
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.000 0.143 0.857
C44.0 Skin of lip
0.000 0.144 0.856
E10-E14 Diabetes mellitus
0.000 0.151 0.849
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.000 0.152 0.848
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.155 0.845
D06 Carcinoma in situ of cervix uteri
0.000 0.159 0.841
J22 Unspecified acute lower respiratory infection
0.000 0.172 0.828
C51-C58 Malignant neoplasms of female genital organs
0.000 0.172 0.828
E50-E64 Other nutritional deficiencies
0.000 0.175 0.825
K22.2 Oesophageal obstruction
0.000 0.175 0.825
E06 Thyroiditis
0.000 0.176 0.824
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.176 0.824
D06.9 Cervix, unspecified
0.000 0.182 0.818
M05-M14 Inflammatory polyarthropathies
0.046 0.186 0.769
J44.9 Chronic obstructive pulmonary disease, unspecified
0.000 0.186 0.814
K22.1 Ulcer of oesophagus
0.000 0.187 0.813
J02.9 Acute pharyngitis, unspecified
0.000 0.188 0.812
E11 Non-insulin-dependent diabetes mellitus
0.000 0.198 0.802
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.072 0.199 0.729
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.000 0.204 0.796
D70-D77 Other diseases of blood and blood-forming organs
0.000 0.205 0.795
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.208 0.792
D80-D89 Certain disorders involving the immune mechanism
0.000 0.211 0.789
D69 Purpura and other haemorrhagic conditions
0.000 0.212 0.788
E11.3 With ophthalmic complications
0.000 0.216 0.784
D45 Polycythaemia vera
0.000 0.217 0.783
K70-K77 Diseases of liver
0.000 0.217 0.783
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.000 0.217 0.783
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.000 0.235 0.765
K35-K38 Diseases of appendix
0.000 0.239 0.761
K29.5 Chronic gastritis, unspecified
0.000 0.239 0.761
C73 Malignant neoplasm of thyroid gland
0.000 0.241 0.759
C81 Hodgkin's disease
0.000 0.242 0.758
D62 Acute posthaemorrhagic anaemia
0.000 0.249 0.751
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.249 0.751
L40-L45 Papulosquamous disorders
0.000 0.254 0.746
K29.1 Other acute gastritis
0.000 0.254 0.746
D69.6 Thrombocytopenia, unspecified
0.000 0.258 0.742
D63 Anaemia in chronic diseases classified elsewhere
0.000 0.259 0.741
K29.2 Alcoholic gastritis
0.000 0.261 0.739
J90-J94 Other diseases of pleura
0.000 0.262 0.738
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.000 0.264 0.736
K92 Other diseases of digestive system
0.000 0.265 0.735
C53 Malignant neoplasm of cervix uteri
0.000 0.268 0.731
M80-M85 Disorders of bone density and structure
0.060 0.274 0.665
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.000 0.278 0.722
E55 Vitamin D deficiency
0.000 0.278 0.722
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.279 0.721
C83 Diffuse non-Hodgkin's lymphoma
0.000 0.281 0.719
C44.9 Malignant neoplasm of skin, unspecified
0.000 0.281 0.719
K22.9 Disease of oesophagus, unspecified
0.000 0.282 0.718
E03.5 Myxoedema coma
0.000 0.284 0.716
E03.4 Atrophy of thyroid (acquired)
0.000 0.284 0.716
E03.3 Postinfectious hypothyroidism
0.000 0.284 0.716
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.284 0.716
E03.1 Congenital hypothyroidism without goitre
0.000 0.284 0.716
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.284 0.716
Chapter I Certain infectious and parasitic diseases
0.000 0.284 0.716
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.284 0.716
E00 Congenital iodine-deficiency syndrome
0.000 0.284 0.716
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.284 0.716
J45.8 Mixed asthma
0.000 0.284 0.716
J45.1 Nonallergic asthma
0.000 0.284 0.716
J41 Simple and mucopurulent chronic bronchitis
0.000 0.285 0.715
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.285 0.715
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.285 0.715
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.285 0.715
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.285 0.714
K90.8 Other intestinal malabsorption
0.000 0.286 0.714
K90.3 Pancreatic steatorrhoea
0.000 0.286 0.714
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.286 0.714
K90.1 Tropical sprue
0.000 0.286 0.714
K70 Alcoholic liver disease
0.000 0.286 0.713
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.287 0.713
C40-C41 Malignant neoplasms of bone and articular cartilage
0.000 0.288 0.712
C44.4 Skin of scalp and neck
0.000 0.288 0.712
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.000 0.290 0.710
K27 Peptic ulcer, site unspecified
0.000 0.290 0.710
Chapter XXII Codes for special purposes
0.000 0.290 0.709
C44.8 Overlapping lesion of skin
0.000 0.291 0.709
C54 Malignant neoplasm of corpus uteri
0.000 0.292 0.708
E07 Other disorders of thyroid
0.000 0.293 0.706
D55-D59 Haemolytic anaemias
0.000 0.294 0.706
J01 Acute sinusitis
0.000 0.296 0.704
K28 Gastrojejunal ulcer
0.000 0.296 0.704
K23 Disorders of oesophagus in diseases classified elsewhere
0.000 0.296 0.704
J03 Acute tonsillitis
0.000 0.298 0.702
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.000 0.299 0.701
C90 Multiple myeloma and malignant plasma cell neoplasms
0.000 0.299 0.701
D75 Other diseases of blood and blood-forming organs
0.000 0.300 0.700
C92 Myeloid leukaemia
0.000 0.300 0.700
E06.3 Autoimmune thyroiditis
0.000 0.301 0.699
K29.9 Gastroduodenitis, unspecified
0.000 0.302 0.698
J45.0 Predominantly allergic asthma
0.000 0.302 0.698
E20-E35 Disorders of other endocrine glands
0.000 0.302 0.698
E11.4 With neurological complications
0.000 0.303 0.697
K26 Duodenal ulcer
0.000 0.304 0.696
D64.8 Other specified anaemias
0.000 0.305 0.695
D64.4 Congenital dyserythropoietic anaemia
0.000 0.305 0.695
D64.3 Other sideroblastic anaemias
0.000 0.305 0.695
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.000 0.305 0.695
D64.1 Secondary sideroblastic anaemia due to disease
0.000 0.305 0.695
D64.0 Hereditary sideroblastic anaemia
0.000 0.305 0.695
L40 Psoriasis
0.000 0.305 0.695
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.000 0.308 0.692
C95 Leukaemia of unspecified cell type
0.000 0.308 0.692
C94 Other leukaemias of specified cell type
0.000 0.308 0.692
C93 Monocytic leukaemia
0.000 0.308 0.692
C86 Other specified types of T/NK-cell lymphoma
0.000 0.308 0.692
C84 Peripheral and cutaneous T-cell lymphomas
0.000 0.308 0.692
C64-C68 Malignant neoplasms of urinary tract
0.000 0.309 0.691
K50-K52 Noninfective enteritis and colitis
0.028 0.318 0.655
J95-J99 Other diseases of the respiratory system
0.000 0.318 0.682
M81 Osteoporosis without pathological fracture
0.032 0.318 0.650
C91 Lymphoid leukaemia
0.000 0.319 0.681
K29.3 Chronic superficial gastritis
0.000 0.320 0.680
B35-B49 Mycoses
0.000 0.321 0.679
J90 Pleural effusion, not elsewhere classified
0.000 0.323 0.677
J04 Acute laryngitis and tracheitis
0.000 0.323 0.677
E05.8 Other thyrotoxicosis
0.000 0.325 0.675
E05.5 Thyroid crisis or storm
0.000 0.325 0.675
E05.4 Thyrotoxicosis factitia
0.000 0.325 0.675
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.325 0.675
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.325 0.675
C85.1 B-cell lymphoma, unspecified
0.000 0.326 0.674
L57 Skin changes due to chronic exposure to nonionising radiation
0.000 0.327 0.673
K90.9 Intestinal malabsorption, unspecified
0.000 0.329 0.671
M05 Seropositive rheumatoid arthritis
0.027 0.329 0.644
J06 Acute upper respiratory infections of multiple and unspecified sites
0.000 0.330 0.670
D68 Other coagulation defects
0.000 0.334 0.666
J05 Acute obstructive laryngitis [croup] and epiglottitis
0.000 0.334 0.665
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.000 0.335 0.665
K92.0 Haematemesis
0.000 0.335 0.665
E03.8 Other specified hypothyroidism
0.000 0.336 0.664
C44.5 Skin of trunk
0.000 0.337 0.663
C09 Malignant neoplasm of tonsil
0.000 0.337 0.663
C53.9 Cervix uteri, unspecified
0.000 0.338 0.662
D47.2 Monoclonal gammopathy
0.000 0.338 0.662
C44.1 Skin of eyelid, including canthus
0.000 0.339 0.661
L80-L99 Other disorders of the skin and subcutaneous tissue
0.000 0.345 0.655
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.345 0.655
B37 Candidiasis
0.000 0.346 0.654
J00 Acute nasopharyngitis [common cold]
0.000 0.346 0.654
K70.9 Alcoholic liver disease, unspecified
0.000 0.347 0.653
M81.9 Osteoporosis, unspecified
0.011 0.348 0.642
C88 Malignant immunoproliferative diseases
0.000 0.350 0.650
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.350 0.650
D86 Sarcoidosis
0.000 0.350 0.650
E55.9 Vitamin D deficiency, unspecified
0.000 0.352 0.648
L57.0 Actinic keratosis
0.000 0.353 0.647
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.353 0.647
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.000 0.354 0.646
C60-C63 Malignant neoplasms of male genital organs
0.000 0.355 0.645
L40.9 Psoriasis, unspecified
0.000 0.356 0.644
C82.7 Other types of follicular non-Hodgkin's lymphoma
0.000 0.357 0.643
C82.6 Cutaneous follicle centre lymphoma
0.000 0.357 0.643
C82.5 Diffuse follicle centre lymphoma
0.000 0.357 0.643
C82.4 Follicular lymphoma grade IIIb
0.000 0.357 0.643
C82.3 Follicular lymphoma grade IIIa
0.000 0.357 0.643
C82.2 Large cell, follicular
0.000 0.357 0.643
C82.1 Mixed small cleaved and large cell, follicular
0.000 0.357 0.643
C82.0 Small cleaved cell, follicular
0.000 0.357 0.643
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.358 0.642
D46 Myelodysplastic syndromes
0.000 0.359 0.641
J21 Acute bronchiolitis
0.000 0.359 0.640
L82 Seborrhoeic keratosis
0.000 0.362 0.638
M81.99 Osteoporosis, unspecified (Site unspecified)
0.000 0.362 0.637
M06.8 Other specified rheumatoid arthritis
0.013 0.367 0.620
M06.4 Inflammatory polyarthropathy
0.013 0.367 0.620
M06.3 Rheumatoid nodule
0.013 0.367 0.620
M06.2 Rheumatoid bursitis
0.013 0.367 0.620
M06.1 Adult-onset Still's disease
0.013 0.367 0.620
M06.0 Seronegative rheumatoid arthritis
0.012 0.367 0.621
K22.3 Perforation of oesophagus
0.000 0.367 0.633
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.000 0.371 0.629
K22.4 Dyskinesia of oesophagus
0.000 0.371 0.629
D02 Carcinoma in situ of middle ear and respiratory system
0.000 0.373 0.627
D01 Carcinoma in situ of other and unspecified digestive organs
0.000 0.373 0.627
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.000 0.373 0.627
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.000 0.374 0.626
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.000 0.374 0.626
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.000 0.374 0.626
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.000 0.374 0.626
D75.1 Secondary polycythaemia
0.000 0.378 0.622
C54.1 Endometrium
0.000 0.379 0.621
D67 Hereditary factor IX deficiency
0.000 0.379 0.621
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.000 0.379 0.621
Z85.8 Personal history of malignant neoplasms of other organs and systems
0.000 0.379 0.621
D47.3 Essential (haemorrhagic) thrombocythaemia
0.000 0.380 0.620
K51 Ulcerative colitis
0.011 0.381 0.609
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.000 0.382 0.618
J02.8 Acute pharyngitis due to other specified organisms
0.000 0.383 0.617
J02.0 Streptococcal pharyngitis
0.000 0.383 0.617
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.383 0.616
D07 Carcinoma in situ of other and unspecified genital organs
0.000 0.384 0.616
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.000 0.385 0.615
C85.0 Lymphosarcoma
0.000 0.385 0.615
K72 Hepatic failure, not elsewhere classified
0.000 0.385 0.615
C75 Malignant neoplasm of other endocrine glands and related structures
0.000 0.385 0.614
C74 Malignant neoplasm of adrenal gland
0.000 0.385 0.614
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.000 0.386 0.614
D05 Carcinoma in situ of breast
0.000 0.386 0.613
E53 Deficiency of other B group vitamins
0.000 0.387 0.613
B37.8 Candidiasis of other sites
0.000 0.387 0.613
A50-A64 Infections with a predominantly sexual mode of transmission
0.000 0.389 0.610
C81.9 Hodgkin's disease, unspecified
0.000 0.390 0.610
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.000 0.390 0.610
E12 Malnutrition-related diabetes mellitus
0.000 0.391 0.609
E11.5 With peripheral circulatory complications
0.000 0.391 0.609
E04 Other non-toxic goitre
0.000 0.392 0.608
Z85 Personal history of malignant neoplasm
0.000 0.393 0.607
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.000 0.394 0.606
J20 Acute bronchitis
0.000 0.394 0.606
K22.8 Other specified diseases of oesophagus
0.000 0.396 0.604
D06.7 Other parts of cervix
0.000 0.397 0.603
D06.1 Exocervix
0.000 0.397 0.603
D06.0 Endocervix
0.000 0.397 0.603
D50-D53 Nutritional anaemias
0.000 0.397 0.603
C67 Malignant neoplasm of bladder
0.000 0.398 0.602
Z85.7 Personal history of other malignant neoplasms of lymphoid, haematopoietic and related tissues
0.000 0.400 0.600
D68.9 Coagulation defect, unspecified
0.000 0.401 0.599
C51 Malignant neoplasm of vulva
0.000 0.401 0.598
C02 Malignant neoplasm of other and unspecified parts of tongue
0.000 0.404 0.596
D69.3 Idiopathic thrombocytopenic purpura
0.000 0.404 0.596
C57 Malignant neoplasm of other and unspecified female genital organs
0.000 0.406 0.594
C58 Malignant neoplasm of placenta
0.000 0.406 0.594
C55 Malignant neoplasm of uterus, part unspecified
0.000 0.406 0.594
C52 Malignant neoplasm of vagina
0.000 0.406 0.594
C83.3 Large cell (diffuse)
0.000 0.407 0.593
K22.0 Achalasia of cardia
0.000 0.408 0.592
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.408 0.592
E63 Other nutritional deficiencies
0.000 0.408 0.592
E56 Other vitamin deficiencies
0.000 0.408 0.592
E51 Thiamine deficiency
0.000 0.408 0.592
E50 Vitamin A deficiency
0.000 0.408 0.592
E60 Dietary zinc deficiency
0.000 0.408 0.592
E59 Dietary selenium deficiency
0.000 0.408 0.592
E58 Dietary calcium deficiency
0.000 0.408 0.592
E54 Ascorbic acid deficiency
0.000 0.408 0.592
E52 Niacin deficiency [pellagra]
0.000 0.408 0.592
E06.9 Thyroiditis, unspecified
0.000 0.409 0.591
E06.5 Other chronic thyroiditis
0.000 0.409 0.591
E06.4 Drug-induced thyroiditis
0.000 0.409 0.591
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.409 0.591
E06.1 Subacute thyroiditis
0.000 0.409 0.591
E06.0 Acute thyroiditis
0.000 0.409 0.591
L10-L14 Bullous disorders
0.000 0.409 0.591
K65-K67 Diseases of peritoneum
0.000 0.410 0.590
K92.1 Melaena
0.000 0.410 0.590
M07 Psoriatic and enteropathic arthropathies
0.030 0.411 0.558
K29.0 Acute haemorrhagic gastritis
0.000 0.414 0.586
M14 Arthropathies in other diseases classified elsewhere
0.033 0.416 0.551
M12 Other specific arthropathies
0.033 0.416 0.551
M09 Juvenile arthritis in diseases classified elsewhere
0.033 0.416 0.551
M08 Juvenile arthritis
0.033 0.416 0.551
M91-M94 Chondropathies
0.048 0.419 0.533
E40-E46 Malnutrition
0.000 0.419 0.580
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.000 0.420 0.580
K37 Unspecified appendicitis
0.000 0.421 0.579
E11.6 With other specified complications
0.000 0.421 0.579
K35 Acute appendicitis
0.000 0.421 0.579
D09 Carcinoma in situ of other and unspecified sites
0.000 0.422 0.578
J95 Postprocedural respiratory disorders, not elsewhere classified
0.000 0.422 0.578
K51.9 Ulcerative colitis, unspecified
0.001 0.422 0.577
E11.8 With unspecified complications
0.000 0.425 0.575
E11.7 With multiple complications
0.000 0.425 0.575
B07 Viral warts
0.000 0.426 0.574
D72 Other disorders of white blood cells
0.000 0.428 0.572
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx
0.000 0.429 0.570
C13 Malignant neoplasm of hypopharynx
0.000 0.429 0.570
C11 Malignant neoplasm of nasopharynx
0.000 0.429 0.570
C10 Malignant neoplasm of oropharynx
0.000 0.429 0.570
C08 Malignant neoplasm of other and unspecified major salivary glands
0.000 0.429 0.570
C06 Malignant neoplasm of other and unspecified parts of mouth
0.000 0.429 0.570
C05 Malignant neoplasm of palate
0.000 0.429 0.570
C04 Malignant neoplasm of floor of mouth
0.000 0.429 0.570
C03 Malignant neoplasm of gum
0.000 0.429 0.570
C00 Malignant neoplasm of lip
0.000 0.429 0.570
C12 Malignant neoplasm of pyriform sinus
0.000 0.429 0.570
C07 Malignant neoplasm of parotid gland
0.000 0.429 0.570
K31 Other diseases of stomach and duodenum
0.000 0.430 0.570
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.000 0.430 0.570
D74 Methaemoglobinaemia
0.000 0.430 0.570
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.000 0.430 0.570
D71 Functional disorders of polymorphonuclear neutrophils
0.000 0.430 0.570
L00-L08 Infections of the skin and subcutaneous tissue
0.000 0.431 0.569
M05.9 Seropositive rheumatoid arthritis, unspecified
0.013 0.432 0.555
C09.9 Tonsil, unspecified
0.000 0.433 0.567
C44.2 Skin of ear and external auricular canal
0.000 0.433 0.567
E13 Other specified diabetes mellitus
0.000 0.433 0.566
D04 Carcinoma in situ of skin
0.000 0.434 0.566
D84 Other immunodeficiencies
0.000 0.434 0.566
D83 Common variable immunodeficiency
0.000 0.434 0.566
D82 Immunodeficiency associated with other major defects
0.000 0.434 0.566
D81 Combined immunodeficiencies
0.000 0.434 0.566
D80 Immunodeficiency with predominantly antibody defects
0.000 0.434 0.566
D69.9 Haemorrhagic condition, unspecified
0.000 0.435 0.565
D69.8 Other specified haemorrhagic conditions
0.000 0.435 0.565
D69.4 Other primary thrombocytopenia
0.000 0.435 0.565
D69.2 Other nonthrombocytopenic purpura
0.000 0.435 0.565
D69.1 Qualitative platelet defects
0.000 0.435 0.565
D69.0 Allergic purpura
0.000 0.435 0.565
K77 Liver disorders in diseases classified elsewhere
0.000 0.438 0.561
K73 Chronic hepatitis, not elsewhere classified
0.000 0.438 0.561
K71 Toxic liver disease
0.000 0.438 0.561
C90.0 Multiple myeloma
0.000 0.439 0.561
C44.6 Skin of upper limb, including shoulder
0.000 0.440 0.560
C92.0 Acute myeloid leukaemia
0.000 0.441 0.559
Z85.1 Personal history of malignant neoplasm of trachea, bronchus and lung
0.000 0.442 0.558
E21.0 Primary hyperparathyroidism
0.000 0.442 0.558
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.000 0.443 0.556
C67.9 Bladder, unspecified
0.000 0.444 0.556
D63.0 Anaemia in neoplastic disease
0.000 0.446 0.553
D63.8 Anaemia in other chronic diseases classified elsewhere
0.000 0.448 0.551
L40.5 Arthropathic psoriasis
0.000 0.449 0.551
M00-M03 Infectious arthropathies
0.054 0.449 0.497
E11.0 With coma
0.000 0.449 0.551
M11 Other crystal arthropathies
0.033 0.449 0.518
D61 Other aplastic anaemias
0.000 0.451 0.549
D47.9 Neoplasm of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue, unspecified
0.000 0.451 0.549
D47.7 Other specified neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.000 0.451 0.549
D47.5 Chronic eosinophilic leukaemia [hypereosinophilic syndrome]
0.000 0.451 0.549
D47.4 Osteomyelofibrosis
0.000 0.451 0.549
D47.0 Histiocytic and mast cell tumours of uncertain and unknown behaviour
0.000 0.451 0.549
J60-J70 Lung diseases due to external agents
0.000 0.451 0.549
K26.9 Unspecified as acute or chronic, without haemorrhage or perforation
0.000 0.451 0.549
D75.8 Other specified diseases of blood and blood-forming organs
0.000 0.451 0.548
D70 Agranulocytosis
0.000 0.452 0.548
L97 Ulcer of lower limb, not elsewhere classified
0.000 0.453 0.547
B37.0 Candidal stomatitis
0.000 0.453 0.547
K36 Other appendicitis
0.000 0.454 0.546
B90-B94 Sequelae of infectious and parasitic diseases
0.000 0.455 0.545
M60-M63 Disorders of muscles
0.055 0.455 0.491
E14 Unspecified diabetes mellitus
0.000 0.456 0.544
J01.9 Acute sinusitis, unspecified
0.000 0.456 0.544
C81.7 Other Hodgkin's disease
0.000 0.456 0.544
C81.4 Lymphocyte-rich classical Hodgkin lymphoma
0.000 0.456 0.544
C81.3 Lymphocytic depletion
0.000 0.456 0.544
C81.2 Mixed cellularity
0.000 0.456 0.544
C81.1 Nodular sclerosis
0.000 0.456 0.544
C81.0 Lymphocytic predominance
0.000 0.456 0.544
K22.5 Diverticulum of oesophagus, acquired
0.000 0.457 0.543
E29 Testicular dysfunction
0.000 0.458 0.542
K51.2 Ulcerative (chronic) proctitis
0.004 0.458 0.538
D86.0 Sarcoidosis of lung
0.000 0.459 0.541
K70.4 Alcoholic hepatic failure
0.000 0.459 0.540
J03.9 Acute tonsillitis, unspecified
0.000 0.460 0.540
D48.5 Skin
0.000 0.462 0.538
J94 Other pleural conditions
0.000 0.462 0.538
E07.9 Disorder of thyroid, unspecified
0.000 0.463 0.537
L44 Other papulosquamous disorders
0.000 0.465 0.535
L41 Parapsoriasis
0.000 0.465 0.535
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.465 0.535
L42 Pityriasis rosea
0.000 0.465 0.535
A63 Other predominantly sexually transmitted diseases, not elsewhere classified
0.000 0.465 0.535
K70.3 Alcoholic cirrhosis of liver
0.000 0.466 0.534
C85.7 Other specified types of non-Hodgkin's lymphoma
0.000 0.468 0.532
C50-C50 Malignant neoplasm of breast
0.000 0.468 0.532
D63.1 Anaemia in other chronic diseases classified elsewhere
0.000 0.468 0.531
K38 Other diseases of appendix
0.000 0.471 0.529
C97 Malignant neoplasms of independent (primary) multiple sites
0.000 0.472 0.528
L59 Other disorders of skin and subcutaneous tissue related to radiation
0.000 0.472 0.528
L58 Radiodermatitis
0.000 0.472 0.528
L56 Other acute skin changes due to ultraviolet radiation
0.000 0.472 0.528
L55 Sunburn
0.000 0.472 0.528
K92.8 Other specified diseases of digestive system
0.000 0.473 0.527
K26.4 Chronic or unspecified with haemorrhage
0.000 0.473 0.526
D66 Hereditary factor VIII deficiency
0.000 0.475 0.525
C53.8 Overlapping lesion of cervix uteri
0.000 0.475 0.524
C53.1 Exocervix
0.000 0.475 0.524
C53.0 Endocervix
0.000 0.475 0.524
D47.1 Chronic myeloproliferative disease
0.000 0.476 0.524
C01 Malignant neoplasm of base of tongue
0.000 0.476 0.524
B25-B34 Other viral diseases
0.000 0.478 0.521
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.000 0.479 0.520
M83 Adult osteomalacia
0.043 0.480 0.477
M82 Osteoporosis in diseases classified elsewhere
0.043 0.480 0.477
K51.8 Other ulcerative colitis
0.005 0.480 0.515
E61 Deficiency of other nutrient elements
0.000 0.480 0.520
M81.98 Osteoporosis, unspecified (Other)
0.006 0.481 0.514
B20-B24 Human immunodeficiency virus [HIV] disease
0.000 0.482 0.518
E55.0 Rickets, active
0.000 0.482 0.517
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified
0.000 0.484 0.515
C83.8 Other types of diffuse non-Hodgkin's lymphoma
0.000 0.484 0.515
C83.7 Burkitt's tumour
0.000 0.484 0.515
C83.6 Undifferentiated (diffuse)
0.000 0.484 0.515
C83.5 Lymphoblastic (diffuse)
0.000 0.484 0.515
C83.4 Immunoblastic (diffuse)
0.000 0.484 0.515
C83.2 Mixed small and large cell (diffuse)
0.000 0.484 0.515
C83.1 Small cleaved cell (diffuse)
0.000 0.484 0.515
K27.9 Unspecified as acute or chronic, without haemorrhage or perforation
0.000 0.485 0.515
B99-B99 Other infectious diseases
0.000 0.486 0.513
B85-B89 Pediculosis, acariasis and other infestations
0.000 0.486 0.513
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.000 0.486 0.513
A75-A79 Rickettsioses
0.000 0.486 0.513
A70-A74 Other diseases caused by chlamydiae
0.000 0.486 0.513
A65-A69 Other spirochaetal diseases
0.000 0.486 0.513
A20-A28 Certain zoonotic bacterial diseases
0.000 0.486 0.513
A15-A19 Tuberculosis
0.000 0.486 0.513
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.487 0.513
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.487 0.513
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.487 0.513
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.487 0.513
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.487 0.513
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.487 0.513
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.487 0.513
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.487 0.513
L43 Lichen planus
0.000 0.487 0.513
J41.8 Mixed simple and mucopurulent chronic bronchitis
0.000 0.487 0.513
J41.1 Mucopurulent chronic bronchitis
0.000 0.487 0.513
J41.0 Simple chronic bronchitis
0.000 0.487 0.513
P90-P96 Other disorders originating in the perinatal period
0.000 0.488 0.512
P80-P83 Conditions involving the integument and temperature regulation of fetus and newborn
0.000 0.488 0.512
P75-P78 Digestive system disorders of fetus and newborn
0.000 0.488 0.512
P70-P74 Transitory endocrine and metabolic disorders specific to fetus and newborn
0.000 0.488 0.512
P50-P61 Haemorrhagic and haematological disorders of fetus and newborn
0.000 0.488 0.512
P35-P39 Infections specific to the perinatal period
0.000 0.488 0.512
P20-P29 Respiratory and cardiovascular disorders specific to the perinatal period
0.000 0.488 0.512
P10-P15 Birth trauma
0.000 0.488 0.512
P05-P08 Disorders related to length of gestation and fetal growth
0.000 0.488 0.512
P00-P04 Fetus and newborn affected by maternal factors and by complications of pregnancy, labour and delivery
0.000 0.488 0.512
M10 Gout
0.027 0.488 0.485
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.052 0.488 0.460
K70.2 Alcoholic fibrosis and sclerosis of liver
0.000 0.488 0.512
K70.0 Alcoholic fatty liver
0.000 0.488 0.512
J47 Bronchiectasis
0.000 0.488 0.512
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.000 0.488 0.511
K93.1 Megacolon in Chagas' disease
0.000 0.488 0.511
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.000 0.488 0.511
J95.8 Other postprocedural respiratory disorders
0.000 0.489 0.511
C42 hematopoietic and reticuloendothelial systems (ICD-O-3 specific)
0.000 0.489 0.511
C41 Malignant neoplasm of bone and articular cartilage of other and unspecified sites
0.000 0.489 0.511
C40 Malignant neoplasm of bone and articular cartilage of limbs
0.000 0.489 0.511
B35 Dermatophytosis
0.000 0.490 0.510
M40-M43 Deforming dorsopathies
0.047 0.490 0.463
J85 Abscess of lung and mediastinum
0.000 0.491 0.509
L08 Other local infections of skin and subcutaneous tissue
0.000 0.491 0.509
K27.7 Chronic without haemorrhage or perforation
0.000 0.491 0.509
K27.6 Chronic or unspecified with both haemorrhage and perforation
0.000 0.491 0.509
K27.5 Chronic or unspecified with perforation
0.000 0.491 0.509
K27.4 Chronic or unspecified with haemorrhage
0.000 0.491 0.509
K27.3 Acute without haemorrhage or perforation
0.000 0.491 0.509
K27.2 Acute with both haemorrhage and perforation
0.000 0.491 0.509
K27.1 Acute with perforation
0.000 0.491 0.509
K27.0 Acute with haemorrhage
0.000 0.491 0.509
D86.9 Sarcoidosis, unspecified
0.000 0.492 0.508
K75 Other inflammatory liver diseases
0.000 0.492 0.508
E11.1 With ketoacidosis
0.000 0.492 0.507
C54.9 Corpus uteri, unspecified
0.000 0.493 0.507
C54.8 Overlapping lesion of corpus uteri
0.000 0.493 0.507
C54.3 Fundus uteri
0.000 0.493 0.507
C54.2 Myometrium
0.000 0.493 0.507

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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