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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs116578934
log Bayes Factor = 13.215
Chromosome 1   position 85,581,898  (GRCh37) Explore rs116578934 on Ensembl!
Variant rs116578934 is part of Cluster X0083

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
M20-M25 Other joint disorders
0.998 0.002 0.000
S60-S69 Injuries to the wrist and hand
0.998 0.002 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.995 0.005 0.000
Chapter VII Diseases of the eye and adnexa
0.993 0.007 0.000
M23 Internal derangement of knee
0.993 0.007 0.000
I60-I69 Cerebrovascular diseases
0.991 0.009 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.990 0.010 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.990 0.010 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.987 0.013 0.000
Chapter VI Diseases of the nervous system
0.987 0.013 0.000
I30-I52 Other forms of heart disease
0.985 0.015 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.985 0.015 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.985 0.015 0.000
M23.23 Derangement of meniscus due to old tear or injury (Medial collateral ligament or Other and unspecified medial meniscus)
0.981 0.019 0.000
S00-S09 Injuries to the head
0.977 0.023 0.000
I73 Other peripheral vascular diseases
0.975 0.025 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.971 0.029 0.000
I42 Cardiomyopathy
0.970 0.030 0.000
M50-M54 Other dorsopathies
0.953 0.047 0.000
G62 Other polyneuropathies
0.952 0.048 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.949 0.051 0.000
M65-M68 Disorders of synovium and tendon
0.948 0.052 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.948 0.052 0.000
I73.9 Peripheral vascular disease, unspecified
0.947 0.053 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.945 0.055 0.000
S01 Open wound of head
0.945 0.055 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.939 0.061 0.000
S61 Open wound of wrist and hand
0.936 0.064 0.000
O60-O75 Complications of labour and delivery
0.930 0.070 0.000
H53-H54 Visual disturbances and blindness
0.923 0.077 0.000
I74 Arterial embolism and thrombosis
0.922 0.078 0.000
M65 Synovitis and tenosynovitis
0.922 0.078 0.000
T84.1 Mechanical complication of internal fixation device of bones of limb
0.917 0.083 0.000
H02 Other disorders of eyelid
0.917 0.083 0.000
M25 Other joint disorders, not elsewhere classified
0.915 0.085 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.912 0.088 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.912 0.088 0.000
I63 Cerebral infarction
0.912 0.088 0.000
G62.9 Polyneuropathy, unspecified
0.910 0.090 0.000
H55-H59 Other disorders of eye and adnexa
0.909 0.091 0.000
S62 Fracture at wrist and hand level
0.900 0.100 0.000
T66-T78 Other and unspecified effects of external causes
0.892 0.108 0.000
Chapter VIII Diseases of the ear and mastoid process
0.891 0.109 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.890 0.110 0.000
H02.8 Other specified disorders of eyelid
0.889 0.111 0.000
M65.3 Trigger finger
0.887 0.113 0.000
S50-S59 Injuries to the elbow and forearm
0.884 0.116 0.000
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)
0.882 0.118 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.882 0.118 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.879 0.121 0.000
S64 Injury of nerves at wrist and hand level
0.878 0.122 0.000
I42.1 Obstructive hypertrophic cardiomyopathy
0.877 0.123 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.871 0.129 0.000
M23.21 Derangement of meniscus due to old tear or injury (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.869 0.131 0.000
I73.0 Raynaud's syndrome
0.869 0.131 0.000
M20 Acquired deformities of fingers and toes
0.867 0.133 0.000
M65.34 Trigger finger-Hand
0.863 0.137 0.000
S00 Superficial injury of head
0.861 0.139 0.000
H54 Blindness and low vision
0.858 0.142 0.000
H90-H95 Other disorders of ear
0.857 0.143 0.000
S40-S49 Injuries to the shoulder and upper arm
0.856 0.144 0.000
I69 Sequelae of cerebrovascular disease
0.856 0.144 0.000
I35 Nonrheumatic aortic valve disorders
0.855 0.145 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.855 0.145 0.000
I61 Intracerebral haemorrhage
0.852 0.148 0.000
G81 Hemiplegia
0.852 0.148 0.000
S51 Open wound of forearm
0.852 0.148 0.000
G90-G99 Other disorders of the nervous system
0.850 0.150 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.849 0.150 0.000
I42.0 Dilated cardiomyopathy
0.847 0.153 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.846 0.154 0.000
M50 Cervical disk disorders
0.838 0.162 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.834 0.166 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.834 0.166 0.000
T84.0 Mechanical complication of internal joint prosthesis
0.830 0.170 0.000
G62.8 Other specified polyneuropathies
0.829 0.171 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.828 0.172 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.828 0.172 0.000
S61.0 Open wound of finger(s) without damage to nail
0.828 0.172 0.000
M22 Disorders of patella
0.828 0.172 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.827 0.173 0.000
L03 Cellulitis
0.826 0.174 0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis
0.824 0.176 0.000
I67 Other cerebrovascular diseases
0.822 0.178 0.000
M51 Other intervertebral disk disorders
0.822 0.178 0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts
0.821 0.179 0.000
I20-I25 Ischaemic heart diseases
0.819 0.181 0.000
S62.6 Fracture of other finger
0.819 0.181 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.818 0.182 0.000
H02.6 Xanthelasma of eyelid
0.818 0.182 0.000
S01.5 Open wound of lip and oral cavity
0.817 0.183 0.000
M05-M14 Inflammatory polyarthropathies
0.814 0.186 0.000
T78 Adverse effects, not elsewhere classified
0.814 0.186 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.814 0.186 0.000
G83 Other paralytic syndromes
0.814 0.186 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.814 0.186 0.000
S01.8 Open wound of other parts of head
0.813 0.187 0.000
I42.8 Other cardiomyopathies
0.813 0.187 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.811 0.189 0.000
M25.7 Osteophyte
0.810 0.190 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.809 0.191 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.809 0.191 0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.807 0.193 0.000
H91 Other hearing loss
0.807 0.193 0.000
M65.4 Radial styloid tenosynovitis [de Quervain]
0.805 0.195 0.000
L40-L45 Papulosquamous disorders
0.804 0.196 0.000
S51.0 Open wound of elbow
0.804 0.196 0.000
I36 Nonrheumatic tricuspid valve disorders
0.804 0.196 0.000
H55 Nystagmus and other irregular eye movements
0.801 0.199 0.000
I30 Acute pericarditis
0.801 0.199 0.000
I65.2 Occlusion and stenosis of carotid artery
0.799 0.201 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.795 0.205 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.795 0.205 0.000
M54 Dorsalgia
0.795 0.205 0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]
0.795 0.205 0.000
M70-M79 Other soft tissue disorders
0.792 0.208 0.000
H30-H36 Disorders of choroid and retina
0.791 0.209 0.000
I42.2 Other hypertrophic cardiomyopathy
0.790 0.210 0.000
S60 Superficial injury of wrist and hand
0.787 0.213 0.000
H90 Conductive and sensorineural hearing loss
0.787 0.213 0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts
0.785 0.215 0.000
I62 Other nontraumatic intracranial haemorrhage
0.785 0.215 0.000
H43-H45 Disorders of vitreous body and globe
0.784 0.216 0.000
I42.9 Cardiomyopathy, unspecified
0.784 0.216 0.000
G81.9 Hemiplegia, unspecified
0.782 0.218 0.000
I31 Other diseases of pericardium
0.778 0.221 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.778 0.222 0.000
S20-S29 Injuries to the thorax
0.776 0.224 0.000
S61.8 Open wound of other parts of wrist and hand
0.775 0.225 0.000
L81 Other disorders of pigmentation
0.775 0.225 0.000
I72 Other aneurysm
0.773 0.227 0.000
T84.2 Mechanical complication of internal fixation device of other bones
0.772 0.228 0.000
H91.9 Hearing loss, unspecified
0.771 0.229 0.000
I46 Cardiac arrest
0.771 0.229 0.000
S62.60 Fracture of other finger (closed)
0.771 0.229 0.000
O85-O92 Complications predominantly related to the puerperium
0.770 0.230 0.000
L05 Pilonidal cyst
0.769 0.231 0.000
S02 Fracture of skull and facial bones
0.768 0.232 0.000
O20 Haemorrhage in early pregnancy
0.766 0.234 0.000
S10-S19 Injuries to the neck
0.761 0.239 0.000
M20.1 Hallux valgus (acquired)
0.761 0.239 0.000
G70-G73 Diseases of myoneural junction and muscle
0.761 0.239 0.000
H54.7 Unspecified visual loss
0.760 0.240 0.000
S70-S79 Injuries to the hip and thigh
0.759 0.241 0.000
L89 Decubitus ulcer
0.759 0.241 0.000
H05 Disorders of orbit
0.758 0.242 0.000
G80 Infantile cerebral palsy
0.757 0.243 0.000
I63.8 Other cerebral infarction
0.757 0.243 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.757 0.243 0.000
G62.0 Drug-induced polyneuropathy
0.757 0.243 0.000
I25 Chronic ischaemic heart disease
0.756 0.244 0.000
S01.2 Open wound of nose
0.755 0.245 0.000
I38 Endocarditis, valve unspecified
0.754 0.246 0.000
M31 Other necrotising vasculopathies
0.753 0.247 0.000
S01.3 Open wound of ear
0.753 0.247 0.000
M54.9 Dorsalgia, unspecified
0.752 0.248 0.000
S67 Crushing injury of wrist and hand
0.751 0.249 0.000
L60-L75 Disorders of skin appendages
0.750 0.250 0.000
L95 Vasculitis limited to skin, not elsewhere classified
0.749 0.251 0.000
L20-L30 Dermatitis and eczema
0.748 0.252 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.747 0.253 0.000
T78.3 Angioneurotic oedema
0.747 0.253 0.000
M20.0 Deformity of finger(s)
0.746 0.254 0.000
M51.2 Other specified intervertebral disk displacement
0.746 0.254 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.746 0.254 0.000
O72 Postpartum haemorrhage
0.745 0.255 0.000
I35.0 Aortic (valve) stenosis
0.744 0.256 0.000
M23.29 Derangement of meniscus due to old tear or injury (Unspecified ligament or Unspecified meniscus)
0.744 0.256 0.000
Chapter XXII Codes for special purposes
0.743 0.256 0.000
S90-S99 Injuries to the ankle and foot
0.742 0.258 0.000
H54.0 Blindness, both eyes
0.742 0.258 0.000
G82 Paraplegia and tetraplegia
0.742 0.258 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.741 0.259 0.000
M25.76 Osteophyte (Lower leg)
0.740 0.260 0.000
L94 Other localised connective tissue disorders
0.739 0.261 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.739 0.261 0.000
O62 Abnormalities of forces of labour
0.738 0.262 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.738 0.262 0.000
S66.0 Injury of long flexor muscle and tendon of thumb at wrist and hand level
0.738 0.262 0.000
S61.1 Open wound of finger(s) with damage to nail
0.737 0.263 0.000
G30-G32 Other degenerative diseases of the nervous system
0.736 0.264 0.000
I05-I09 Chronic rheumatic heart diseases
0.733 0.267 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.731 0.269 0.000
S64.4 Injury of digital nerve of other finger
0.728 0.272 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.728 0.272 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.728 0.272 0.000
S01.1 Open wound of eyelid and periocular area
0.727 0.272 0.000
M91-M94 Chondropathies
0.727 0.273 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.726 0.274 0.000
H02.5 Other disorders affecting eyelid function
0.726 0.274 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.725 0.275 0.000
S01.0 Open wound of scalp
0.724 0.276 0.000
G60 Hereditary and idiopathic neuropathy
0.723 0.277 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.723 0.277 0.000
H53 Visual disturbances
0.723 0.277 0.000
S00.9 Superficial injury of head, part unspecified
0.723 0.277 0.000
M23.5 Chronic instability of knee
0.722 0.278 0.000
H10-H13 Disorders of conjunctiva
0.722 0.278 0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.722 0.278 0.000
T92 Sequelae of injuries of upper limb
0.722 0.278 0.000
M54.99 Dorsalgia, unspecified (Site unspecified)
0.721 0.279 0.000
I20 Angina pectoris
0.720 0.280 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.720 0.280 0.000
H01 Other inflammation of eyelid
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
G83.4 Cauda equina syndrome
0.717 0.283 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.716 0.284 0.000
M34 Systemic sclerosis
0.716 0.284 0.000
M33 Dermatopolymyositis
0.716 0.284 0.000
M32 Systemic lupus erythematosus
0.716 0.284 0.000
M30 Polyarteritis nodosa and related conditions
0.716 0.284 0.000
S65 Injury of blood vessels at wrist and hand level
0.715 0.285 0.000
M72 Fibroblastic disorders
0.715 0.285 0.000
I35.8 Other aortic valve disorders
0.715 0.285 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.715 0.285 0.000
T87 Complications peculiar to reattachment and amputation
0.713 0.287 0.000
M23.4 Loose body in knee
0.713 0.287 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.712 0.288 0.000
H33 Retinal detachments and breaks
0.712 0.288 0.000
M23.9 Internal derangement of knee, unspecified
0.712 0.288 0.000
M23.1 Discoid meniscus (congenital)
0.712 0.288 0.000
M23.0 Cystic meniscus
0.712 0.288 0.000
M86-M90 Other osteopathies
0.711 0.289 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.711 0.289 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.711 0.289 0.000
O66 Other obstructed labour
0.710 0.289 0.000
M23.20 Derangement of meniscus due to old tear or injury (Multiple sites)
0.710 0.289 0.000
M25.78 Osteophyte (Other)
0.710 0.290 0.000
H57 Other disorders of eye and adnexa
0.710 0.290 0.000
M23.27 Derangement of meniscus due to old tear or injury-Capsular
0.710 0.290 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.709 0.290 0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft
0.708 0.292 0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts
0.708 0.292 0.000
T84.3 Mechanical complication of other bone devices, implants and grafts
0.708 0.292 0.000
I74.5 Embolism and thrombosis of iliac artery
0.707 0.292 0.000
L84 Corns and callosities
0.706 0.294 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.706 0.294 0.000
I52 Other heart disorders in diseases classified elsewhere
0.706 0.294 0.000
I48 Atrial fibrillation and flutter
0.706 0.294 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.706 0.294 0.000
I41 Myocarditis in diseases classified elsewhere
0.706 0.294 0.000
I40 Acute myocarditis
0.706 0.294 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.706 0.294 0.000
I37 Pulmonary valve disorders
0.706 0.294 0.000
I32 Pericarditis in diseases classified elsewhere
0.706 0.294 0.000
L10-L14 Bullous disorders
0.706 0.294 0.000
M24 Other specific joint derangements
0.706 0.294 0.000
S00.1 Contusion of eyelid and periocular area
0.705 0.295 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.705 0.295 0.000
G95 Other diseases of spinal cord
0.704 0.296 0.000
I63.9 Cerebral infarction, unspecified
0.704 0.296 0.000
T42.4 Benzodiazepines
0.704 0.296 0.000
T79-T79 Certain early complications of trauma
0.702 0.297 0.000
T85.2 Mechanical complication of intraocular lens
0.702 0.298 0.000
S08 Traumatic amputation of part of head
0.701 0.299 0.000
S07 Crushing injury of head
0.701 0.299 0.000
S05 Injury of eye and orbit
0.701 0.299 0.000
S04 Injury of cranial nerves
0.701 0.299 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.701 0.299 0.000
S62.4 Multiple fractures of metacarpal bones
0.700 0.299 0.000
T86 Failure and rejection of transplanted organs and tissues
0.700 0.300 0.000
I51 Complications and ill-defined descriptions of heart disease
0.700 0.300 0.000
T43.2 Other and unspecified antidepressants
0.700 0.300 0.000
I73.8 Other specified peripheral vascular diseases
0.699 0.301 0.000
I73.1 Thromboangiitis obliterans [Buerger]
0.699 0.301 0.000
I61.4 Intracerebral haemorrhage in cerebellum
0.698 0.302 0.000
S61.9 Open wound of wrist and hand, part unspecified
0.697 0.303 0.000
O42 Premature rupture of membranes
0.697 0.303 0.000
H90.5 Sensorineural hearing loss, unspecified
0.697 0.303 0.000
G64 Other disorders of peripheral nervous system
0.696 0.304 0.000
I61.9 Intracerebral haemorrhage, unspecified
0.696 0.304 0.000
I42.7 Cardiomyopathy due to drugs and other external agents
0.696 0.304 0.000
I42.6 Alcoholic cardiomyopathy
0.696 0.304 0.000
I42.5 Other restrictive cardiomyopathy
0.696 0.304 0.000
I42.4 Endocardial fibroelastosis
0.696 0.304 0.000
I42.3 Endomyocardial (eosinophilic) disease
0.696 0.304 0.000
L83 Acanthosis nigricans
0.695 0.305 0.000
M25.4 Effusion of joint
0.695 0.305 0.000
I60 Subarachnoid haemorrhage
0.695 0.305 0.000
S51.8 Open wound of other parts of forearm
0.694 0.306 0.000
S06 Intracranial injury
0.694 0.306 0.000
S63.4 Traumatic rupture of ligament of finger at metacarpophalangeal and interphalangeal joint(s)
0.694 0.306 0.000
S68 Traumatic amputation of wrist and hand
0.694 0.306 0.000
O75.8 Other specified complications of labour and delivery
0.694 0.306 0.000
I33 Acute and subacute endocarditis
0.693 0.307 0.000
M23.22 Derangement of meniscus due to old tear or injury (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.693 0.307 0.000
S64.3 Injury of digital nerve of thumb
0.693 0.307 0.000
O61 Failed induction of labour
0.692 0.308 0.000
M50.0 Cervical disk disorder with myelopathy
0.692 0.308 0.000
H58 Other disorders of eye and adnexa in diseases classified elsewhere
0.692 0.308 0.000
T85.4 Mechanical complication of breast prosthesis and implant
0.692 0.308 0.000
M65.44 Radial styloid tenosynovitis [de Quervain] (Hand)
0.691 0.309 0.000
H02.3 Blepharochalasis
0.691 0.309 0.000
L03.1 Cellulitis of other parts of limb
0.690 0.310 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.690 0.310 0.000
I70 Atherosclerosis
0.689 0.311 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.689 0.311 0.000
E10-E14 Diabetes mellitus
0.688 0.312 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.687 0.312 0.000
S64.2 Injury of radial nerve at wrist and hand level
0.687 0.313 0.000
L40 Psoriasis
0.687 0.313 0.000
L03.8 Cellulitis of other sites
0.687 0.313 0.000
H16 Keratitis
0.687 0.313 0.000
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level
0.687 0.313 0.000
M23.24 Derangement of meniscus due to old tear or injury (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.686 0.314 0.000
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified
0.685 0.314 0.000
S63.6 Sprain and strain of finger(s)
0.685 0.314 0.000
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts
0.685 0.315 0.000
S00.7 Multiple superficial injuries of head
0.685 0.315 0.000
L93 Lupus erythematosus
0.685 0.315 0.000
H02.1 Ectropion of eyelid
0.684 0.316 0.000
M53 Other dorsopathies, not elsewhere classified
0.683 0.316 0.000
M21 Other acquired deformities of limbs
0.683 0.317 0.000
O24 Diabetes mellitus in pregnancy
0.682 0.318 0.000
G62.2 Polyneuropathy due to other toxic agents
0.682 0.318 0.000
G62.1 Alcoholic polyneuropathy
0.682 0.318 0.000
I47 Paroxysmal tachycardia
0.682 0.318 0.000
M23.61 Other spontaneous disruption of ligament(s) of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.681 0.319 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.681 0.319 0.000
O63 Long labour
0.681 0.319 0.000
G61 Inflammatory polyneuropathy
0.681 0.319 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.680 0.319 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.680 0.320 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.680 0.320 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.680 0.320 0.000
M66 Spontaneous rupture of synovium and tendon
0.680 0.320 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.680 0.320 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.679 0.320 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.679 0.320 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.679 0.320 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.679 0.320 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.679 0.320 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.679 0.320 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.679 0.320 0.000
T36 Poisoning by systemic antibiotics
0.679 0.320 0.000
I45 Other conduction disorders
0.679 0.321 0.000
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level
0.679 0.321 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.678 0.322 0.000
M23.8 Other internal derangements of knee
0.677 0.322 0.000
H03 Disorders of eyelid in diseases classified elsewhere
0.677 0.323 0.000
S01.7 Multiple open wounds of head
0.677 0.323 0.000
S01.4 Open wound of cheek and temporomandibular area
0.677 0.323 0.000
S69 Other and unspecified injuries of wrist and hand
0.677 0.323 0.000
T83.1 Mechanical complication of other urinary devices and implants
0.676 0.324 0.000
Chapter I Certain infectious and parasitic diseases
0.676 0.324 0.000
I36.1 Nonrheumatic tricuspid (valve) insufficiency
0.674 0.326 0.000
M20.4 Other hammer toe(s) (acquired)
0.674 0.326 0.000
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.673 0.327 0.000
L87 Transepidermal elimination disorders
0.673 0.327 0.000
L88 Pyoderma gangrenosum
0.673 0.327 0.000
L86 Keratoderma in diseases classified elsewhere
0.673 0.327 0.000
L80 Vitiligo
0.673 0.327 0.000
I67.1 Cerebral aneurysm, nonruptured
0.672 0.328 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.672 0.328 0.000
Chapter V Mental and behavioural disorders
0.672 0.328 0.000
S51.9 Open wound of forearm, part unspecified
0.671 0.329 0.000
E00-E07 Disorders of thyroid gland
0.671 0.329 0.000
S61.7 Multiple open wounds of wrist and hand
0.671 0.329 0.000
G63.2 Diabetic polyneuropathy
0.670 0.330 0.000
H54.4 Blindness, one eye
0.669 0.331 0.000
I67.9 Cerebrovascular disease, unspecified
0.669 0.331 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.669 0.331 0.000
I69.0 Sequelae of subarachnoid haemorrhage
0.668 0.332 0.000
M20.3 Other deformity of hallux (acquired)
0.668 0.332 0.000
M10 Gout
0.667 0.333 0.000
S62.5 Fracture of thumb
0.667 0.333 0.000
S40 Superficial injury of shoulder and upper arm
0.667 0.333 0.000
O74 Complications of anaesthesia during labour and delivery
0.667 0.333 0.000
O73 Retained placenta and membranes, without haemorrhage
0.667 0.333 0.000
O71 Other obstetric trauma
0.667 0.333 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.667 0.333 0.000
O60 Preterm delivery
0.667 0.333 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.667 0.333 0.000
L05.9 Pilonidal cyst without abscess
0.667 0.333 0.000
Q50-Q56 Congenital malformations of genital organs
0.666 0.334 0.000
I30.1 Infective pericarditis
0.666 0.334 0.000
M22.4 Chondromalacia patellae
0.664 0.336 0.000
M72.0 Palmar fascial fibromatosis [Dupuytren]
0.663 0.337 0.000
S60.9 Superficial injury of wrist and hand, unspecified
0.662 0.338 0.000
I74.9 Embolism and thrombosis of unspecified artery
0.661 0.339 0.000
I74.8 Embolism and thrombosis of other arteries
0.661 0.339 0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.661 0.339 0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.661 0.339 0.000
I74.0 Embolism and thrombosis of abdominal aorta
0.661 0.339 0.000
M65.8 Other synovitis and tenosynovitis
0.661 0.339 0.000
M65.2 Calcific tendinitis
0.661 0.339 0.000
M65.1 Other infective (teno)synovitis
0.661 0.339 0.000
M65.0 Abscess of tendon sheath
0.661 0.339 0.000
M25.5 Pain in joint
0.661 0.339 0.000
H00 Hordeolum and chalazion
0.660 0.340 0.000
O75.6 Delayed delivery after spontaneous or unspecified rupture of membranes
0.660 0.340 0.000
I31.3 Pericardial effusion (noninflammatory)
0.659 0.340 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.659 0.341 0.000
S00.3 Superficial injury of nose
0.659 0.341 0.000
L81.4 Other melanin hyperpigmentation
0.658 0.342 0.000
H02.7 Other degenerative disorders of eyelid and periocular area
0.658 0.342 0.000
H02.2 Lagophthalmos
0.658 0.342 0.000
T59 Toxic effect of other gases, fumes and vapours
0.656 0.344 0.000
M25.9 Joint disorder, unspecified
0.656 0.344 0.000
M25.8 Other specified joint disorders
0.656 0.344 0.000
M25.3 Other instability of joint
0.656 0.344 0.000
M25.2 Flail joint
0.656 0.344 0.000
M25.1 Fistula of joint
0.656 0.344 0.000
M25.0 Haemarthrosis
0.656 0.344 0.000
H18 Other disorders of cornea
0.656 0.344 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.655 0.345 0.000
L04 Acute lymphadenitis
0.654 0.346 0.000
L01 Impetigo
0.654 0.346 0.000
L00 Staphylococcal scalded skin syndrome
0.654 0.346 0.000
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.654 0.346 0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.654 0.346 0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.654 0.346 0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.654 0.346 0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.654 0.346 0.000
I20.9 Angina pectoris, unspecified
0.654 0.346 0.000
S43.0 Dislocation of shoulder joint
0.654 0.346 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.653 0.347 0.000
L50-L54 Urticaria and erythema
0.653 0.347 0.000
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level
0.653 0.347 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.652 0.348 0.000
I71 Aortic aneurysm and dissection
0.652 0.348 0.000
S01.9 Open wound of head, part unspecified
0.652 0.348 0.000
O44 Placenta praevia
0.651 0.349 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.650 0.350 0.000
T78.4 Allergy, unspecified
0.649 0.350 0.000
Chapter XX External causes of morbidity and mortality
0.648 0.352 0.000
M50.2 Other cervical disk displacement
0.646 0.354 0.000
S62.8 Fracture of other and unspecified parts of wrist and hand
0.645 0.354 0.000
S62.7 Multiple fractures of fingers
0.645 0.354 0.000
S62.2 Fracture of first metacarpal bone
0.645 0.354 0.000
S62.1 Fracture of other carpal bone(s)
0.645 0.354 0.000
S62.0 Fracture of navicular [scaphoid] bone of hand
0.645 0.354 0.000
O36 Maternal care for other known or suspected foetal problems
0.645 0.355 0.000
M50.1 Cervical disk disorder with radiculopathy
0.645 0.355 0.000
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side
0.644 0.355 0.000
L03.2 Cellulitis of face
0.644 0.356 0.000
L92 Granulomatous disorders of skin and subcutaneous tissue
0.644 0.356 0.000
H90.3 Sensorineural hearing loss, bilateral
0.642 0.358 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.642 0.358 0.000
M22.8 Other disorders of patella
0.642 0.358 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.641 0.359 0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts
0.640 0.360 0.000
T75 Effects of other external causes
0.639 0.361 0.000
T74 Maltreatment syndromes
0.639 0.361 0.000
T73 Effects of other deprivation
0.639 0.361 0.000
T70 Effects of air pressure and water pressure
0.639 0.361 0.000
T69 Other effects of reduced temperature
0.639 0.361 0.000
T67 Effects of heat and light
0.639 0.361 0.000
T71 Asphyxiation
0.639 0.361 0.000
T68 Hypothermia
0.639 0.361 0.000
T66 Unspecified effects of radiation
0.639 0.361 0.000
M65.43 Radial styloid tenosynovitis [de Quervain] (Forearm)
0.639 0.361 0.000
L89.1 Stage II decubitus ulcer
0.639 0.361 0.000
O21 Excessive vomiting in pregnancy
0.638 0.362 0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft
0.638 0.362 0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis
0.638 0.362 0.000
T82.4 Mechanical complication of vascular dialysis catheter
0.638 0.362 0.000
T82.3 Mechanical complication of other vascular grafts
0.638 0.362 0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts
0.638 0.362 0.000
T82.0 Mechanical complication of heart valve prosthesis
0.638 0.362 0.000
T90 Sequelae of injuries of head
0.638 0.362 0.000
S00.2 Other superficial injuries of eyelid and periocular area
0.637 0.363 0.000
M65.39 Trigger finger-Site unspec
0.636 0.364 0.000
M65.38 Trigger finger-Other
0.636 0.364 0.000
M65.37 Trigger finger-Ankle/foot
0.636 0.364 0.000
M65.36 Trigger finger-Lower leg
0.636 0.364 0.000
M65.35 Trigger finger-Pelvic/thigh
0.636 0.364 0.000
M65.33 Trigger finger-Forearm
0.636 0.364 0.000
M65.32 Trigger finger-Upper arm
0.636 0.364 0.000
M65.31 Trigger finger-Shldr region
0.636 0.364 0.000
M65.30 Trigger finger-Mult sites
0.636 0.364 0.000
A30-A49 Other bacterial diseases
0.636 0.364 0.000
H43 Disorders of vitreous body
0.634 0.366 0.000
O41 Other disorders of amniotic fluid and membranes
0.634 0.366 0.000
S59 Other and unspecified injuries of forearm
0.634 0.366 0.000
S58 Traumatic amputation of forearm
0.634 0.366 0.000
S57 Crushing injury of forearm
0.634 0.366 0.000
S56 Injury of muscle and tendon at forearm level
0.634 0.366 0.000
S55 Injury of blood vessels at forearm level
0.634 0.366 0.000
S54 Injury of nerves at forearm level
0.634 0.366 0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow
0.634 0.366 0.000
Q60-Q64 Congenital malformations of the urinary system
0.634 0.366 0.000
M50.3 Other cervical disk degeneration
0.633 0.367 0.000
O20.8 Other haemorrhage in early pregnancy
0.633 0.367 0.000
M06 Other rheumatoid arthritis
0.633 0.367 0.000
O80-O84 Delivery
0.633 0.367 0.000
S66.9 Injury of unspecified muscle and tendon at wrist and hand level
0.632 0.368 0.000
S66.8 Injury of other muscles and tendons at wrist and hand level
0.632 0.368 0.000
S66.7 Injury of multiple extensor muscles and tendons at wrist and hand level
0.632 0.368 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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