TreeWAS – Variant ID: rs1168029

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E78.0 Pure hypercholesterolaemia	1.000	0.000	0.000
E78.5 Hyperlipidaemia, unspecified	1.000	0.000	0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias	1.000	0.000	0.000
E78.1 Pure hyperglyceridaemia	0.869	0.131	0.000
E78.6 Lipoprotein deficiency	0.732	0.268	0.000
E78.3 Hyperchylomicronaemia	0.718	0.282	0.000
E78.8 Other disorders of lipoprotein metabolism	0.711	0.289	0.000
E78.4 Other hyperlipidaemia	0.681	0.319	0.000
E89.0 Postprocedural hypothyroidism	0.533	0.467	0.000
E78.2 Mixed hyperlipidaemia	0.528	0.472	0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.522	0.478	0.000
E70-E90 Metabolic disorders	0.522	0.478	0.000
E78.9 Disorder of lipoprotein metabolism, unspecified	0.478	0.522	0.000
E80 Disorders of porphyrin and bilirubin metabolism	0.406	0.594	0.000
E79 Disorders of purine and pyrimidine metabolism	0.405	0.595	0.000
E89.8 Other postprocedural endocrine and metabolic disorders	0.395	0.605	0.000
E84 Cystic fibrosis	0.384	0.616	0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.379	0.620	0.000
E89.3 Postprocedural hypopituitarism	0.378	0.622	0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.374	0.625	0.000
E89.5 Postprocedural testicular hypofunction	0.374	0.625	0.000
E77 Disorders of glycoprotein metabolism	0.374	0.625	0.000
E76 Disorders of glycosaminoglycan metabolism	0.374	0.625	0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.374	0.625	0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.374	0.625	0.000
E72 Other disorders of amino-acid metabolism	0.373	0.627	0.000
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.363	0.637	0.000
E85 Amyloidosis	0.350	0.650	0.000
E89.1 Postprocedural hypoinsulinaemia	0.340	0.660	0.000
E73 Lactose intolerance	0.337	0.663	0.000
E74 Other disorders of carbohydrate metabolism	0.327	0.673	0.000
E89.2 Postprocedural hypoparathyroidism	0.325	0.675	0.000
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease	0.322	0.678	0.000
E80.1 Porphyria cutanea tarda	0.319	0.681	0.000
E80.4 Gilbert's syndrome	0.319	0.681	0.000
E70 Disorders of aromatic amino-acid metabolism	0.304	0.695	0.000
E89.4 Postprocedural ovarian failure	0.298	0.702	0.000
E87 Other disorders of fluid, electrolyte and acid-base balance	0.297	0.703	0.000
E75.5 Other lipid storage disorders	0.295	0.705	0.000
E80.2 Other porphyria	0.293	0.707	0.000
E80.5 Crigler-Najjar syndrome	0.291	0.708	0.000
E80.3 Defects of catalase and peroxydase	0.291	0.708	0.000
E80.0 Hereditary erythropoietic porphyria	0.291	0.708	0.000
E79.9 Disorder of purine and pyrimidine metabolism, unspecified	0.291	0.709	0.000
E79.8 Other disorders of purine and pyrimidine metabolism	0.291	0.709	0.000
E79.1 Lesch-Nyhan syndrome	0.291	0.709	0.000
E87.6 Hypokalaemia	0.289	0.711	0.000
E84.9 Cystic fibrosis, unspecified	0.285	0.715	0.000
E80.6 Other disorders of bilirubin metabolism	0.278	0.722	0.000
E80.7 Disorder of bilirubin metabolism, unspecified	0.276	0.724	0.000
E72.1 Disorders of sulphur-bearing amino-acid metabolism	0.276	0.724	0.000
E84.8 Cystic fibrosis with other manifestations	0.275	0.725	0.000
E84.1 Cystic fibrosis with intestinal manifestations	0.275	0.725	0.000
E84.0 Cystic fibrosis with pulmonary manifestations	0.275	0.725	0.000
E75.6 Lipid storage disorder, unspecified	0.272	0.728	0.000
E75.4 Neuronal ceroid lipofuscinosis	0.272	0.728	0.000
E75.3 Sphingolipidosis, unspecified	0.272	0.728	0.000
E75.1 Other gangliosidosis	0.272	0.728	0.000
E75.0 GM2 gangliosidosis	0.272	0.728	0.000
E71.3 Disorders of fatty-acid metabolism	0.269	0.731	0.000
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified	0.269	0.731	0.000
E71.1 Other disorders of branched-chain amino-acid metabolism	0.269	0.731	0.000
E71.0 Maple-syrup-urine disease	0.269	0.731	0.000
E76.9 Disorder of glucosaminoglycan metabolism, unspecified	0.269	0.731	0.000
E76.8 Other disorders of glucosaminoglycan metabolism	0.269	0.731	0.000
E76.3 Mucopolysaccharidosis, unspecified	0.269	0.731	0.000
E76.2 Other mucopolysaccharidoses	0.269	0.731	0.000
E76.1 Mucopolysaccharidosis, type II	0.269	0.731	0.000
E76.0 Mucopolysaccharidosis, type I	0.269	0.731	0.000
E77.9 Disorder of glycoprotein metabolism, unspecified	0.269	0.731	0.000
E77.8 Other disorders of glycoprotein metabolism	0.269	0.731	0.000
E77.1 Defects in glycoprotein degradation	0.269	0.731	0.000
E77.0 Defects in posttranslational modification of lysosomal enzymes	0.269	0.731	0.000
E88 Other metabolic disorders	0.268	0.732	0.000
E72.9 Disorder of amino-acid metabolism, unspecified	0.268	0.732	0.000
E72.8 Other specified disorders of amino-acid metabolism	0.268	0.732	0.000
E72.5 Disorders of glycine metabolism	0.268	0.732	0.000
E72.4 Disorders of ornithine metabolism	0.268	0.732	0.000
E72.3 Disorders of lysine and hydroxylysine metabolism	0.268	0.732	0.000
E72.2 Disorders of urea cycle metabolism	0.268	0.732	0.000
E85.3 Secondary systemic amyloidosis	0.266	0.733	0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified	0.261	0.739	0.000
E72.0 Disorders of amino-acid transport	0.258	0.742	0.000
E85.2 Heredofamilial amyloidosis, unspecified	0.251	0.749	0.000
E85.1 Neuropathic heredofamilial amyloidosis	0.251	0.749	0.000
E85.0 Nonneuropathic heredofamilial amyloidosis	0.251	0.749	0.000
E87.5 Hyperkalaemia	0.251	0.749	0.000
E75.2 Other sphingolipidosis	0.250	0.750	0.000
E85.8 Other amyloidosis	0.249	0.751	0.000
E73.8 Other lactose intolerance	0.242	0.758	0.000
E73.1 Secondary lactase deficiency	0.242	0.758	0.000
E73.0 Congenital lactase deficiency	0.242	0.758	0.000
E85.9 Amyloidosis, unspecified	0.241	0.758	0.000
E74.9 Disorder of carbohydrate metabolism, unspecified	0.235	0.765	0.000
E74.8 Other specified disorders of carbohydrate metabolism	0.235	0.765	0.000
E74.4 Disorders of pyruvate metabolism and gluconeogenesis	0.235	0.765	0.000
E74.2 Disorders of galactose metabolism	0.235	0.765	0.000
E74.1 Disorders of fructose metabolism	0.235	0.765	0.000
E74.0 Glycogen storage disease	0.235	0.765	0.000
E88.1 Lipodystrophy, not elsewhere classified	0.225	0.775	0.000
E85.4 Organ-limited amyloidosis	0.221	0.779	0.000
E70.9 Disorder of aromatic amino-acid metabolism, unspecified	0.218	0.781	0.000
E70.8 Other disorders of aromatic amino-acid metabolism	0.218	0.781	0.000
E70.2 Disorders of tyrosine metabolism	0.218	0.781	0.000
E70.1 Other hyperphenylalaninaemias	0.218	0.781	0.000
E70.0 Classical phenylketonuria	0.218	0.781	0.000
E87.4 Mixed disorder of acid-base balance	0.213	0.787	0.000
E73.9 Lactose intolerance, unspecified	0.205	0.795	0.000
E88.3 Tumour lysis syndrome	0.192	0.808	0.000
E74.3 Other disorders of intestinal carbohydrate absorption	0.188	0.812	0.000
E88.8 Other specified metabolic disorders	0.183	0.817	0.000
E88.9 Metabolic disorder, unspecified	0.180	0.819	0.000
E10.3 With ophthalmic complications	0.164	0.836	0.000
E10 Insulin-dependent diabetes mellitus	0.164	0.836	0.000
E10.6 With other specified complications	0.150	0.850	0.000
E70.3 Albinism	0.148	0.851	0.001
E10.0 With coma	0.147	0.853	0.000
E10.9 Without complications	0.146	0.854	0.000
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.144	0.855	0.000
E87.0 Hyperosmolality and hypernatraemia	0.140	0.860	0.000
E83 Disorders of mineral metabolism	0.137	0.863	0.000
E10.4 With neurological complications	0.131	0.869	0.000
E10-E14 Diabetes mellitus	0.131	0.869	0.000
E87.7 Fluid overload	0.130	0.870	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.127	0.873	0.000
E10.7 With multiple complications	0.124	0.876	0.000
E87.3 Alkalosis	0.123	0.877	0.000
E10.1 With ketoacidosis	0.122	0.878	0.000
E88.2 Lipomatosis, not elsewhere classified	0.118	0.881	0.001
E10.5 With peripheral circulatory complications	0.112	0.888	0.000
E83.9 Disorder of mineral metabolism, unspecified	0.107	0.893	0.000
E83.5 Disorders of calcium metabolism	0.099	0.901	0.000
E83.8 Other disorders of mineral metabolism	0.099	0.901	0.000
E83.2 Disorders of zinc metabolism	0.099	0.901	0.000
E83.0 Disorders of copper metabolism	0.099	0.901	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.096	0.904	0.000
E12 Malnutrition-related diabetes mellitus	0.094	0.906	0.000
E10.8 With unspecified complications	0.093	0.907	0.000
E13 Other specified diabetes mellitus	0.091	0.909	0.000
E10.2 With renal complications	0.086	0.914	0.000
E83.4 Disorders of magnesium metabolism	0.086	0.914	0.000
E40-E46 Malnutrition	0.078	0.922	0.000
E16 Other disorders of pancreatic internal secretion	0.074	0.926	0.000
E14 Unspecified diabetes mellitus	0.074	0.926	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.070	0.930	0.000
E15 Nondiabetic hypoglycaemic coma	0.069	0.931	0.000
E12.9 Without complications	0.067	0.932	0.000
E12.8 With unspecified complications	0.067	0.932	0.000
E12.7 With multiple complications	0.067	0.932	0.000
E12.6 With other specified complications	0.067	0.932	0.000
E12.5 With peripheral circulatory complications	0.067	0.932	0.000
E12.4 With neurological complications	0.067	0.932	0.000
E12.3 With ophthalmic complications	0.067	0.932	0.000
E12.2 With renal complications	0.067	0.932	0.000
E12.1 With ketoacidosis	0.067	0.932	0.000
E12.0 With coma	0.067	0.932	0.000
E13.3 With ophthalmic complications	0.066	0.934	0.000
E13.8 With unspecified complications	0.065	0.934	0.000
E13.7 With multiple complications	0.065	0.934	0.000
E13.6 With other specified complications	0.065	0.934	0.000
E13.5 With peripheral circulatory complications	0.065	0.934	0.000
E13.4 With neurological complications	0.065	0.934	0.000
E13.2 With renal complications	0.065	0.934	0.000
E13.1 With ketoacidosis	0.065	0.934	0.000
E13.0 With coma	0.065	0.934	0.000
E14.3 With ophthalmic complications	0.064	0.936	0.000
E65-E68 Obesity and other hyperalimentation	0.062	0.938	0.000
E13.9 Without complications	0.062	0.938	0.000
E14.0 With coma	0.059	0.941	0.000
E14.2 Withrenal complications	0.057	0.943	0.000
E44 Protein-energy malnutrition of moderate and mild degree	0.056	0.944	0.000
E45 Retarded development following protein-energy malnutrition	0.056	0.944	0.000
E43 Unspecified severe protein-energy malnutrition	0.056	0.944	0.000
E42 Marasmic kwashiorkor	0.056	0.944	0.000
E41 Nutritional marasmus	0.056	0.944	0.000
E40 Kwashiorkor	0.056	0.944	0.000
E14.6 With other specified complications	0.055	0.945	0.000
E16.9 Disorder of pancreatic internal secretion, unspecified	0.053	0.946	0.000
E16.8 Other specified disorders of pancreatic internal secretion	0.053	0.946	0.000
E16.4 Abnormal secretion of gastrin	0.053	0.946	0.000
E16.3 Increased secretion of glucagon	0.053	0.946	0.000
E14.7 With multiple complications	0.053	0.946	0.000
E86 Volume depletion	0.053	0.947	0.000
E14.4 With neurological complications	0.053	0.947	0.000
E14.5 With peripheral circulatory complications	0.052	0.948	0.000
E16.1 Other hypoglycaemia	0.051	0.948	0.000
E14.8 With unspecified complications	0.051	0.949	0.000
E83.3 Disorders of phosphorus metabolism	0.050	0.950	0.000
E65 Localised adiposity	0.047	0.953	0.000
E67 Other hyperalimentation	0.045	0.955	0.000
E68 Sequelae of hyperalimentation	0.045	0.955	0.000
E87.1 Hypo-osmolality and hyponatraemia	0.044	0.956	0.000
E46 Unspecified protein-energy malnutrition	0.042	0.958	0.000
E44.1 Mild protein-energy malnutrition	0.040	0.960	0.000
E44.0 Moderate protein-energy malnutrition	0.040	0.960	0.000
E14.1 With ketoacidosis	0.038	0.962	0.000
E87.2 Acidosis	0.037	0.963	0.000
E50-E64 Other nutritional deficiencies	0.035	0.965	0.000
E67.8 Other specified hyperalimentation	0.032	0.967	0.000
E67.3 Hypervitaminosis D	0.032	0.967	0.000
E67.2 Megavitamin-B6 syndrome	0.032	0.967	0.000
E67.1 Hypercarotenaemia	0.032	0.967	0.000
E67.0 Hypervitaminosis A	0.032	0.967	0.000
E56 Other vitamin deficiencies	0.027	0.973	0.000
E54 Ascorbic acid deficiency	0.026	0.974	0.000
E64 Sequelae of malnutrition and other nutritional deficiencies	0.025	0.974	0.000
E50 Vitamin A deficiency	0.025	0.974	0.000
E60 Dietary zinc deficiency	0.025	0.974	0.000
E59 Dietary selenium deficiency	0.025	0.974	0.000
E52 Niacin deficiency [pellagra]	0.025	0.974	0.000
G45.9 Transient cerebral ischaemic attack, unspecified	0.000	0.974	0.026
E63 Other nutritional deficiencies	0.025	0.975	0.000
E58 Dietary calcium deficiency	0.024	0.976	0.000
G56.2 Lesion of ulnar nerve	0.000	0.977	0.023
G56.8 Other mononeuropathies of upper limb	0.000	0.977	0.023
E51 Thiamine deficiency	0.022	0.978	0.000
G56 Mononeuropathies of upper limb	0.000	0.979	0.021
E56.1 Deficiency of vitamin K	0.021	0.979	0.000
G56.3 Lesion of radial nerve	0.000	0.979	0.021
E61 Deficiency of other nutrient elements	0.020	0.980	0.000
E55 Vitamin D deficiency	0.020	0.980	0.000
E83.1 Disorders of iron metabolism	0.020	0.980	0.000
E56.9 Vitamin deficiency, unspecified	0.019	0.980	0.000
E56.8 Deficiency of other vitamins	0.019	0.980	0.000
E56.0 Deficiency of vitamin E	0.019	0.980	0.000
E50.9 Vitamin A deficiency, unspecified	0.018	0.981	0.000
E50.8 Other manifestations of vitamin A deficiency	0.018	0.981	0.000
E50.7 Other ocular manifestations of vitamin A deficiency	0.018	0.981	0.000
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.018	0.981	0.000
E50.5 Vitamin A deficiency with night blindness	0.018	0.981	0.000
E50.4 Vitamin A deficiency with keratomalacia	0.018	0.981	0.000
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.018	0.981	0.000
E50.2 Vitamin A deficiency with corneal xerosis	0.018	0.981	0.000
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.018	0.981	0.000
E50.0 Vitamin A deficiency with conjunctival xerosis	0.018	0.981	0.000
E64.9 Sequelae of unspecified nutritional deficiency	0.018	0.981	0.000
E64.8 Sequelae of other nutritional deficiencies	0.018	0.981	0.000
E64.3 Sequelae of rickets	0.018	0.981	0.000
E64.2 Sequelae of vitamin C deficiency	0.018	0.981	0.000
E64.1 Sequelae of vitamin A deficiency	0.018	0.981	0.000
E64.0 Sequelae of protein-energy malnutrition	0.018	0.981	0.000
E63.8 Other specified nutritional deficiencies	0.018	0.982	0.000
E63.1 Imbalance of constituents of food intake	0.018	0.982	0.000
E63.0 Essential fatty acid [EFA] deficiency	0.018	0.982	0.000
E63.9 Nutritional deficiency, unspecified	0.017	0.983	0.000
E53 Deficiency of other B group vitamins	0.017	0.983	0.000
E51.9 Thiamine deficiency, unspecified	0.016	0.984	0.000
E51.8 Other manifestations of thiamine deficiency	0.016	0.984	0.000
E51.1 Beriberi	0.016	0.984	0.000
G56.1 Other lesions of median nerve	0.000	0.984	0.016
E61.9 Deficiency of nutrient element, unspecified	0.015	0.985	0.000
E61.8 Deficiency of other specified nutrient elements	0.015	0.985	0.000
E61.7 Deficiency of multiple nutrient elements	0.015	0.985	0.000
E61.6 Vanadium deficiency	0.015	0.985	0.000
E61.5 Molybdenum deficiency	0.015	0.985	0.000
E61.4 Chromium deficiency	0.015	0.985	0.000
E61.3 Manganese deficiency	0.015	0.985	0.000
E61.0 Copper deficiency	0.015	0.985	0.000
G56.4 Causalgia	0.000	0.985	0.015
E55.0 Rickets, active	0.014	0.986	0.000
E11 Non-insulin-dependent diabetes mellitus	0.014	0.986	0.000
E61.1 Iron deficiency	0.014	0.986	0.000
E11.8 With unspecified complications	0.013	0.987	0.000
E51.2 Wernicke's encephalopathy	0.012	0.987	0.000
G56.9 Mononeuropathy of upper limb, unspecified	0.000	0.987	0.012
E53.1 Pyridoxine deficiency	0.012	0.987	0.000
E53.0 Riboflavin deficiency	0.012	0.987	0.000
E53.9 Vitamin B deficiency, unspecified	0.012	0.988	0.000
M35.0 Sicca syndrome [Sjogren]	0.000	0.988	0.012
E61.2 Magnesium deficiency	0.011	0.988	0.000
E11.3 With ophthalmic complications	0.011	0.989	0.000
M80.98 Unspecified osteoporosis with pathological fracture (Other)	0.000	0.989	0.011
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)	0.011	0.989	0.000
E00-E07 Disorders of thyroid gland	0.010	0.989	0.000
E11.7 With multiple complications	0.010	0.990	0.000
Z75.1 Person awaiting admission to adequate facility elsewhere	0.000	0.990	0.010
E11.6 With other specified complications	0.010	0.990	0.000
G45 Transient cerebral ischaemic attacks and related syndromes	0.000	0.990	0.010
M07.30 Other psoriatic arthropathies (Multiple sites)	0.000	0.990	0.010
H90.5 Sensorineural hearing loss, unspecified	0.010	0.990	0.000
M80.9 Unspecified osteoporosis with pathological fracture	0.000	0.990	0.010
H90 Conductive and sensorineural hearing loss	0.009	0.991	0.000
H90.0 Conductive hearing loss, bilateral	0.009	0.991	0.000
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)	0.000	0.991	0.009
E03 Other hypothyroidism	0.009	0.991	0.000
G43.9 Migraine, unspecified	0.000	0.991	0.009
E16.2 Hypoglycaemia, unspecified	0.009	0.991	0.000
H90.6 Mixed conductive and sensorineural hearing loss, bilateral	0.009	0.991	0.000
H90.2 Conductive hearing loss, unspecified	0.009	0.991	0.000
G40.9 Epilepsy, unspecified	0.000	0.991	0.009
H90.8 Mixed conductive and sensorineural hearing loss, unspecified	0.009	0.991	0.000
S06.6 Traumatic subarachnoid haemorrhage	0.008	0.992	0.000
E55.9 Vitamin D deficiency, unspecified	0.008	0.992	0.000
H90.3 Sensorineural hearing loss, bilateral	0.008	0.992	0.000
E03.9 Hypothyroidism, unspecified	0.008	0.992	0.000
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)	0.008	0.992	0.000
G43 Migraine	0.000	0.992	0.008
E11.4 With neurological complications	0.008	0.992	0.000
M80.99 Unspecified osteoporosis with pathological fracture (Site unspecified)	0.000	0.992	0.008
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.007	0.992	0.000
E00 Congenital iodine-deficiency syndrome	0.007	0.992	0.000
Q60.0 Renal agenesis, unilateral	0.000	0.992	0.008
M80.10 Postoophorectomy osteoporosis with pathological fracture (Multiple sites)	0.000	0.992	0.008
G45.0 Vertebro-basilar artery syndrome	0.000	0.992	0.008
M07.39 Other psoriatic arthropathies (Site unspecified)	0.000	0.992	0.008
E66 Obesity	0.008	0.992	0.000
E03.1 Congenital hypothyroidism without goitre	0.007	0.992	0.000
E11.0 With coma	0.007	0.993	0.000
G45.2 Multiple and bilateral precerebral artery syndromes	0.000	0.993	0.007
S22.40 Multiple fractures of ribs (closed)	0.007	0.993	0.000
M07.3 Other psoriatic arthropathies	0.000	0.993	0.007
G43.8 Other migraine	0.000	0.993	0.007
S06.5 Traumatic subdural haemorrhage	0.007	0.993	0.000
E11.1 With ketoacidosis	0.007	0.993	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.007	0.993	0.000
M80.97 Unspecified osteoporosis with pathological fracture (Ankle and foot)	0.000	0.993	0.007
M80.96 Unspecified osteoporosis with pathological fracture (Lower leg)	0.000	0.993	0.007
M80.94 Unspecified osteoporosis with pathological fracture (Hand)	0.000	0.993	0.007
M80.93 Unspecified osteoporosis with pathological fracture (Forearm)	0.000	0.993	0.007
M80.92 Unspecified osteoporosis with pathological fracture (Upper arm)	0.000	0.993	0.007
M80.91 Unspecified osteoporosis with pathological fracture (Shoulder region)	0.000	0.993	0.007
H90.7 Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.007	0.993	0.000
M80.1 Postoophorectomy osteoporosis with pathological fracture	0.000	0.993	0.007
G45.8 Other transient cerebral ischaemic attacks and related syndromes	0.000	0.993	0.007
E02 Subclinical iodine-deficiency hypothyroidism	0.007	0.993	0.000
G40 Epilepsy	0.000	0.993	0.007
G40-G47 Episodic and paroxysmal disorders	0.000	0.993	0.007
G40.6 Grand mal seizures, unspecified (with or without petit mal)	0.000	0.993	0.007
S06 Intracranial injury	0.007	0.993	0.000
M80 Osteoporosis with pathological fracture	0.000	0.993	0.007
E03.5 Myxoedema coma	0.006	0.993	0.000
E03.4 Atrophy of thyroid (acquired)	0.006	0.993	0.000
E03.3 Postinfectious hypothyroidism	0.006	0.993	0.000
E20-E35 Disorders of other endocrine glands	0.006	0.993	0.000
E11.2 With renal complications	0.006	0.994	0.000
S06.61 Traumatic subarachnoid haemorrhage (with open intracranial wound)	0.006	0.994	0.000
G45.1 Carotid artery syndrome (hemispheric)	0.000	0.994	0.006
M80.95 Unspecified osteoporosis with pathological fracture (Pelvic region and thigh)	0.000	0.994	0.006
C22.0 Liver cell carcinoma	0.000	0.994	0.006
G43.2 Status migrainosus	0.000	0.994	0.006
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.005	0.994	0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.005	0.994	0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.005	0.994	0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.005	0.994	0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.005	0.994	0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.005	0.994	0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.005	0.994	0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.005	0.994	0.000
M07.31 Other psoriatic arthropathies (Shoulder region)	0.000	0.994	0.006
G45.4 Transient global amnesia	0.000	0.994	0.006
E11.5 With peripheral circulatory complications	0.006	0.994	0.000
M07.34 Other psoriatic arthropathies (Hand)	0.000	0.994	0.006
E66.1 Drug-induced obesity	0.006	0.994	0.000
G43.0 Migraine without aura [common migraine]	0.000	0.994	0.006
C44.5 Skin of trunk	0.000	0.994	0.006
S06.8 Other intracranial injuries	0.005	0.994	0.000
M07.33 Other psoriatic arthropathies (Forearm)	0.000	0.994	0.005
M07.32 Other psoriatic arthropathies (Upper arm)	0.000	0.994	0.005
M07.38 Other psoriatic arthropathies (Other)	0.000	0.994	0.005
E23 Hypofunction and other disorders of pituitary gland	0.006	0.994	0.000
G43.3 Complicated migraine	0.000	0.994	0.005
G40.4 Other generalised epilepsy and epileptic syndromes	0.000	0.995	0.005
S06.1 Traumatic cerebral oedema	0.005	0.995	0.000
E03.0 Congenital hypothyroidism with diffuse goitre	0.005	0.995	0.000
S06.51 Traumatic subdural haemorrhage (with open intracranial wound)	0.005	0.995	0.000
E25 Adrenogenital disorders	0.005	0.995	0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)	0.000	0.995	0.005
M80.19 Postoophorectomy osteoporosis with pathological fracture (Site unspecified)	0.000	0.995	0.005
M80.18 Postoophorectomy osteoporosis with pathological fracture (Other)	0.000	0.995	0.005
M80.17 Postoophorectomy osteoporosis with pathological fracture (Ankle and foot)	0.000	0.995	0.005
M80.16 Postoophorectomy osteoporosis with pathological fracture (Lower leg)	0.000	0.995	0.005
M80.15 Postoophorectomy osteoporosis with pathological fracture (Pelvic region and thigh)	0.000	0.995	0.005
M80.14 Postoophorectomy osteoporosis with pathological fracture (Hand)	0.000	0.995	0.005
M80.13 Postoophorectomy osteoporosis with pathological fracture (Forearm)	0.000	0.995	0.005
M80.12 Postoophorectomy osteoporosis with pathological fracture (Upper arm)	0.000	0.995	0.005
M80.11 Postoophorectomy osteoporosis with pathological fracture (Shoulder region)	0.000	0.995	0.005
E66.0 Obesity due to excess calories	0.005	0.995	0.000
E04.2 Non-toxic multinodular goitre	0.000	0.995	0.005
E14.9 Without complications	0.005	0.995	0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes	0.000	0.995	0.005
G43.1 Migraine with aura [classical migraine]	0.000	0.995	0.005
Z87.0 Personal history of diseases of the respiratory system	0.005	0.995	0.000
S06.3 Focal brain injury	0.005	0.995	0.000
L20.9 Atopic dermatitis, unspecified	0.005	0.995	0.000
R09.8 Other specified symptoms and signs involving the circulatory and respiratory systems	0.000	0.995	0.005
G45.3 Amaurosis fugax	0.000	0.995	0.005
M80.5 Idiopathic osteoporosis with pathological fracture	0.000	0.995	0.005
S06.7 Intracranial injury with prolonged coma	0.005	0.995	0.000
M80.4 Drug-induced osteoporosis with pathological fracture	0.000	0.995	0.005
M80.3 Postsurgical malabsorption osteoporosis with pathological fracture	0.000	0.995	0.005
M80.2 Osteoporosis of disuse with pathological fracture	0.000	0.995	0.005
S06.4 Epidural haemorrhage	0.005	0.995	0.000
G40.8 Other epilepsy	0.000	0.995	0.005
R21 Rash and other nonspecific skin eruption	0.005	0.995	0.000
E31 Polyglandular dysfunction	0.005	0.995	0.000
E03.8 Other specified hypothyroidism	0.005	0.995	0.000
E23.6 Other disorders of pituitary gland	0.005	0.995	0.000
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset	0.000	0.995	0.005
M80.8 Other osteoporosis with pathological fracture	0.000	0.995	0.005
N60.2 Fibroadenosis of breast	0.000	0.995	0.005
E35 Disorders of endocrine glands in diseases classified elsewhere	0.005	0.995	0.000
E30 Disorders of puberty, not elsewhere classified	0.005	0.995	0.000
G44 Other headache syndromes	0.000	0.995	0.005
S82.20 Fracture of shaft of tibia (closed)	0.000	0.995	0.005
S06.9 Intracranial injury, unspecified	0.005	0.995	0.000
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures	0.000	0.995	0.005
K31.1 Adult hypertrophic pyloric stenosis	0.000	0.995	0.005
E05 Thyrotoxicosis [hyperthyroidism]	0.005	0.995	0.000
C84.4 Peripheral T-cell lymphoma	0.005	0.995	0.000
E32 Diseases of thymus	0.005	0.995	0.000
E29 Testicular dysfunction	0.005	0.995	0.000
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side	0.005	0.995	0.000
S06.80 Other intracranial injuries (without open intracranial wound)	0.005	0.995	0.000
E20 Hypoparathyroidism	0.005	0.995	0.000
S06.2 Diffuse brain injury	0.005	0.995	0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.004	0.995	0.000
M07.36 Other psoriatic arthropathies (Lower leg)	0.000	0.995	0.004
H21.8 Other specified disorders of iris and ciliary body	0.005	0.995	0.000
S06.10 Traumatic cerebral oedema (without open intracranial wound)	0.004	0.995	0.000
G44.0 Cluster headache syndrome	0.000	0.995	0.004
E26 Hyperaldosteronism	0.004	0.995	0.000
E66.2 Extreme obesity with alveolar hypoventilation	0.004	0.995	0.000
M80.52 Idiopathic osteoporosis with pathological fracture (Upper arm)	0.000	0.996	0.004
E05.8 Other thyrotoxicosis	0.004	0.996	0.000
E23.0 Hypopituitarism	0.004	0.996	0.000
Y88.3 Sequelae of surgical and medical procedures as the cause of abnormal reaction of the patient or of later complication, without mention of misadventure at the time of the procedure	0.004	0.996	0.000
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.000	0.996	0.004
S06.0 Concussion	0.004	0.996	0.000
G46 Vascular syndromes of brain in cerebrovascular diseases	0.000	0.996	0.004
S06.81 Other intracranial injuries (with open intracranial wound)	0.004	0.996	0.000
I34.1 Mitral (valve) prolapse	0.004	0.996	0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.004	0.996	0.000
E23.1 Drug-induced hypopituitarism	0.004	0.996	0.000
R09.2 Respiratory arrest	0.000	0.996	0.004
G41 Status epilepticus	0.000	0.996	0.004
S06.11 Traumatic cerebral oedema (with open intracranial wound)	0.004	0.996	0.000
H90.4 Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.004	0.996	0.000
S02.10 Fracture of base of skull (closed)	0.004	0.996	0.000
M80.81 Other osteoporosis with pathological fracture (Shoulder region)	0.000	0.996	0.004
E25.9 Adrenogenital disorder, unspecified	0.004	0.996	0.000
E25.8 Other adrenogenital disorders	0.004	0.996	0.000
G44.1 Vascular headache, not elsewhere classified	0.000	0.996	0.004
G40.5 Special epileptic syndromes	0.000	0.996	0.004
R09 Other symptoms and signs involving the circulatory and respiratory systems	0.000	0.996	0.004
E23.2 Diabetes insipidus	0.004	0.996	0.000
H36.0 Diabetic retinopathy	0.004	0.996	0.000
S06.30 Focal brain injury (without open intracranial wound)	0.004	0.996	0.000
Z75 Problems related to medical facilities and other health care	0.000	0.996	0.004
M70.65 Trochanteric bursitis-Pelvic/Thigh	0.004	0.996	0.000
E34 Other endocrine disorders	0.004	0.996	0.000
S22.4 Multiple fractures of ribs	0.004	0.996	0.000
S06.31 Focal brain injury (with open intracranial wound)	0.004	0.996	0.000
E31.0 Autoimmune polyglandular failure	0.004	0.996	0.000
E07 Other disorders of thyroid	0.004	0.996	0.000
G40.7 Petit mal, unspecified, without grand mal seizures	0.000	0.996	0.004
M80.29 Osteoporosis of disuse with pathological fracture (Site unspecified)	0.000	0.996	0.004
M80.28 Osteoporosis of disuse with pathological fracture (Other)	0.000	0.996	0.004
M80.27 Osteoporosis of disuse with pathological fracture (Ankle and foot)	0.000	0.996	0.004
M80.26 Osteoporosis of disuse with pathological fracture (Lower leg)	0.000	0.996	0.004
M80.25 Osteoporosis of disuse with pathological fracture (Pelvic region and thigh)	0.000	0.996	0.004
M80.24 Osteoporosis of disuse with pathological fracture (Hand)	0.000	0.996	0.004
M80.23 Osteoporosis of disuse with pathological fracture (Forearm)	0.000	0.996	0.004
M80.22 Osteoporosis of disuse with pathological fracture (Upper arm)	0.000	0.996	0.004
M80.21 Osteoporosis of disuse with pathological fracture (Shoulder region)	0.000	0.996	0.004
M80.20 Osteoporosis of disuse with pathological fracture (Multiple sites)	0.000	0.996	0.004
M80.39 Postsurgical malabsorption osteoporosis with pathological fracture (Site unspecified)	0.000	0.996	0.004
M80.38 Postsurgical malabsorption osteoporosis with pathological fracture (Other)	0.000	0.996	0.004
M80.37 Postsurgical malabsorption osteoporosis with pathological fracture (Ankle and foot)	0.000	0.996	0.004
M80.36 Postsurgical malabsorption osteoporosis with pathological fracture (Lower leg)	0.000	0.996	0.004
M80.35 Postsurgical malabsorption osteoporosis with pathological fracture (Pelvic region and thigh)	0.000	0.996	0.004
M80.34 Postsurgical malabsorption osteoporosis with pathological fracture (Hand)	0.000	0.996	0.004
M80.33 Postsurgical malabsorption osteoporosis with pathological fracture (Forearm)	0.000	0.996	0.004
M80.32 Postsurgical malabsorption osteoporosis with pathological fracture (Upper arm)	0.000	0.996	0.004
M80.31 Postsurgical malabsorption osteoporosis with pathological fracture (Shoulder region)	0.000	0.996	0.004
M80.30 Postsurgical malabsorption osteoporosis with pathological fracture (Multiple sites)	0.000	0.996	0.004
M80.49 Drug-induced osteoporosis with pathological fracture (Site unspecified)	0.000	0.996	0.004
M80.48 Drug-induced osteoporosis with pathological fracture (Other)	0.000	0.996	0.004
M80.47 Drug-induced osteoporosis with pathological fracture (Ankle and foot)	0.000	0.996	0.004
M80.46 Drug-induced osteoporosis with pathological fracture (Lower leg)	0.000	0.996	0.004
M80.45 Drug-induced osteoporosis with pathological fracture (Pelvic region and thigh)	0.000	0.996	0.004
M80.44 Drug-induced osteoporosis with pathological fracture (Hand)	0.000	0.996	0.004
M80.43 Drug-induced osteoporosis with pathological fracture (Forearm)	0.000	0.996	0.004
M80.42 Drug-induced osteoporosis with pathological fracture (Upper arm)	0.000	0.996	0.004
M80.41 Drug-induced osteoporosis with pathological fracture (Shoulder region)	0.000	0.996	0.004
M80.40 Drug-induced osteoporosis with pathological fracture (Multiple sites)	0.000	0.996	0.004
M80.59 Idiopathic osteoporosis with pathological fracture (Site unspecified)	0.000	0.996	0.004
M80.58 Idiopathic osteoporosis with pathological fracture (Other)	0.000	0.996	0.004
M80.57 Idiopathic osteoporosis with pathological fracture (Ankle and foot)	0.000	0.996	0.004
M80.56 Idiopathic osteoporosis with pathological fracture (Lower leg)	0.000	0.996	0.004
M80.55 Idiopathic osteoporosis with pathological fracture (Pelvic region and thigh)	0.000	0.996	0.004
M80.54 Idiopathic osteoporosis with pathological fracture (Hand)	0.000	0.996	0.004
M80.53 Idiopathic osteoporosis with pathological fracture (Forearm)	0.000	0.996	0.004
M80.51 Idiopathic osteoporosis with pathological fracture (Shoulder region)	0.000	0.996	0.004
S06.41 Epidural haemorrhage (with open intracranial wound)	0.004	0.996	0.000
S06.71 Intracranial injury with prolonged coma (with open intracranial wound)	0.004	0.996	0.000
S06.70 Intracranial injury with prolonged coma (without open intracranial wound)	0.004	0.996	0.000
E23.7 Disorder of pituitary gland, unspecified	0.004	0.996	0.000
Z75.3 Unavailability and inaccessibility of health-care facilities	0.000	0.996	0.004
C84 Peripheral and cutaneous T-cell lymphomas	0.004	0.996	0.000
S06.40 Epidural haemorrhage (without open intracranial wound)	0.004	0.996	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations