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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs116843064
log Bayes Factor = 18.2988
Chromosome 19   position 8,429,323  (GRCh37) Explore rs116843064 on Ensembl!
Variant rs116843064 is listed in the   GWAS Catalog   ⇪
Variant rs116843064 is part of Cluster X0034

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I25 Chronic ischaemic heart disease
0.000 0.000 1.000
I20-I25 Ischaemic heart diseases
0.000 0.000 1.000
I25.1 Atherosclerotic heart disease
0.000 0.000 1.000
I20 Angina pectoris
0.000 0.000 1.000
I20.9 Angina pectoris, unspecified
0.000 0.000 1.000
I25.2 Old myocardial infarction
0.000 0.000 1.000
E78.0 Pure hypercholesterolaemia
0.000 0.002 0.998
I21 Acute myocardial infarction
0.000 0.002 0.998
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.004 0.996
I21.0 Acute transmural myocardial infarction of anterior wall
0.000 0.017 0.983
Chapter IX Diseases of the circulatory system
0.000 0.019 0.981
Z95.5 Presence of coronary angioplasty implant and graft
0.000 0.020 0.980
Z95 Presence of cardiac and vascular implants and grafts
0.000 0.021 0.979
Z95.1 Presence of aortocoronary bypass graft
0.000 0.027 0.973
I25.9 Chronic ischaemic heart disease, unspecified
0.000 0.027 0.973
I20.0 Unstable angina
0.000 0.036 0.964
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.043 0.957
I21.9 Acute myocardial infarction, unspecified
0.000 0.063 0.937
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.066 0.934
Z95.0 Presence of cardiac pacemaker
0.000 0.097 0.903
I10-I15 Hypertensive diseases
0.000 0.102 0.898
E78.5 Hyperlipidaemia, unspecified
0.000 0.117 0.883
E70-E90 Metabolic disorders
0.000 0.128 0.872
I73 Other peripheral vascular diseases
0.000 0.128 0.872
I21.4 Acute subendocardial myocardial infarction
0.000 0.130 0.870
E11 Non-insulin-dependent diabetes mellitus
0.000 0.139 0.861
I60-I69 Cerebrovascular diseases
0.000 0.140 0.860
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.140 0.860
E10-E14 Diabetes mellitus
0.000 0.141 0.859
E11.9 Without complications
0.000 0.143 0.857
I73.9 Peripheral vascular disease, unspecified
0.000 0.181 0.819
I10 Essential (primary) hypertension
0.000 0.192 0.808
Z95.8 Presence of other cardiac and vascular implants and grafts
0.000 0.199 0.801
E11.3 With ophthalmic complications
0.000 0.202 0.798
I67 Other cerebrovascular diseases
0.000 0.215 0.785
I77 Other disorders of arteries and arterioles
0.000 0.217 0.783
I30-I52 Other forms of heart disease
0.000 0.217 0.783
I95-I99 Other and unspecified disorders of the circulatory system
0.000 0.231 0.769
I20.1 Angina pectoris with documented spasm
0.000 0.242 0.758
I21.2 Acute transmural myocardial infarction of other sites
0.000 0.243 0.757
I12 Hypertensive renal disease
0.000 0.247 0.753
Z95.3 Presence of xenogenic heart valve
0.000 0.256 0.744
I05-I09 Chronic rheumatic heart diseases
0.000 0.259 0.741
I74 Arterial embolism and thrombosis
0.000 0.264 0.736
I22 Subsequent myocardial infarction
0.000 0.268 0.732
I25.5 Ischaemic cardiomyopathy
0.000 0.270 0.730
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.000 0.270 0.730
Z95.4 Presence of other heart-valve replacement
0.000 0.273 0.727
I25.6 Silent myocardial ischaemia
0.000 0.283 0.717
I25.4 Coronary artery aneurysm
0.000 0.283 0.717
I25.3 Aneurysm of heart
0.000 0.283 0.717
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.283 0.717
I23 Certain current complications following acute myocardial infarction
0.000 0.283 0.717
I35 Nonrheumatic aortic valve disorders
0.000 0.284 0.716
I77.1 Stricture of artery
0.000 0.284 0.716
I21.X Presumed acute myicardial infaction (unconfirmed)
0.000 0.284 0.715
I21.3 Acute transmural myocardial infarction of unspecified site
0.000 0.284 0.715
E00-E07 Disorders of thyroid gland
0.000 0.285 0.715
Z95.2 Presence of prosthetic heart valve
0.000 0.286 0.714
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.000 0.293 0.707
I00-I02 Acute rheumatic fever
0.000 0.297 0.703
I64 Stroke, not specified as haemorrhage or infarction
0.000 0.298 0.702
I78 Diseases of capillaries
0.000 0.311 0.689
E78.8 Other disorders of lipoprotein metabolism
0.000 0.314 0.686
E78.6 Lipoprotein deficiency
0.000 0.314 0.686
E78.4 Other hyperlipidaemia
0.000 0.314 0.686
E78.3 Hyperchylomicronaemia
0.000 0.314 0.686
E78.2 Mixed hyperlipidaemia
0.000 0.314 0.686
E78.1 Pure hyperglyceridaemia
0.000 0.314 0.686
I70 Atherosclerosis
0.000 0.314 0.686
I67.9 Cerebrovascular disease, unspecified
0.000 0.319 0.681
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.330 0.670
I72 Other aneurysm
0.000 0.330 0.670
I21.1 Acute transmural myocardial infarction of inferior wall
0.000 0.335 0.665
I12.0 Hypertensive renal disease with renal failure
0.000 0.336 0.664
I73.0 Raynaud's syndrome
0.000 0.339 0.661
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.341 0.659
E03 Other hypothyroidism
0.000 0.341 0.659
I20.8 Other forms of angina pectoris
0.000 0.343 0.657
E11.4 With neurological complications
0.000 0.346 0.654
I60 Subarachnoid haemorrhage
0.000 0.347 0.653
I15 Secondary hypertension
0.000 0.356 0.644
I13 Hypertensive heart and renal disease
0.000 0.356 0.644
E10 Insulin-dependent diabetes mellitus
0.000 0.356 0.644
I42 Cardiomyopathy
0.000 0.358 0.642
I47 Paroxysmal tachycardia
0.000 0.358 0.642
I67.8 Other specified cerebrovascular diseases
0.000 0.363 0.637
I61 Intracerebral haemorrhage
0.000 0.368 0.632
E88 Other metabolic disorders
0.000 0.368 0.632
E85 Amyloidosis
0.000 0.375 0.625
E84 Cystic fibrosis
0.000 0.375 0.625
E79 Disorders of purine and pyrimidine metabolism
0.000 0.375 0.625
E77 Disorders of glycoprotein metabolism
0.000 0.375 0.625
E76 Disorders of glycosaminoglycan metabolism
0.000 0.375 0.625
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.375 0.625
E74 Other disorders of carbohydrate metabolism
0.000 0.375 0.625
E73 Lactose intolerance
0.000 0.375 0.625
E72 Other disorders of amino-acid metabolism
0.000 0.375 0.625
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.375 0.625
E70 Disorders of aromatic amino-acid metabolism
0.000 0.375 0.625
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.375 0.625
I73.8 Other specified peripheral vascular diseases
0.000 0.375 0.625
I73.1 Thromboangiitis obliterans [Buerger]
0.000 0.375 0.625
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.375 0.624
E03.9 Hypothyroidism, unspecified
0.000 0.381 0.619
E11.8 With unspecified complications
0.000 0.383 0.617
E11.7 With multiple complications
0.000 0.383 0.617
E11.6 With other specified complications
0.000 0.383 0.617
E11.1 With ketoacidosis
0.000 0.383 0.617
E11.0 With coma
0.000 0.383 0.617
I68 Cerebrovascular disorders in diseases classified elsewhere
0.000 0.383 0.617
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.000 0.383 0.617
E40-E46 Malnutrition
0.000 0.383 0.616
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.384 0.616
E13 Other specified diabetes mellitus
0.000 0.384 0.616
E12 Malnutrition-related diabetes mellitus
0.000 0.384 0.616
I35.2 Aortic (valve) stenosis with insufficiency
0.000 0.387 0.613
I95 Hypotension
0.000 0.388 0.612
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system
0.000 0.388 0.612
I35.1 Aortic (valve) insufficiency
0.000 0.390 0.610
I51 Complications and ill-defined descriptions of heart disease
0.000 0.392 0.608
I34 Nonrheumatic mitral valve disorders
0.000 0.392 0.607
I67.2 Cerebral atherosclerosis
0.000 0.393 0.606
I24 Other acute ischaemic heart diseases
0.000 0.393 0.606
I38 Endocarditis, valve unspecified
0.000 0.395 0.605
I11 Hypertensive heart disease
0.000 0.395 0.605
E11.5 With peripheral circulatory complications
0.000 0.396 0.604
E11.2 With renal complications
0.000 0.404 0.596
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.000 0.405 0.595
I08 Multiple valve diseases
0.000 0.410 0.590
I45 Other conduction disorders
0.000 0.412 0.588
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.000 0.413 0.587
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.000 0.414 0.586
E50-E64 Other nutritional deficiencies
0.000 0.414 0.586
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.000 0.417 0.583
I27 Other pulmonary heart diseases
0.000 0.424 0.576
Z93 Artificial opening status
0.000 0.426 0.574
I67.1 Cerebral aneurysm, nonruptured
0.000 0.430 0.570
I62 Other nontraumatic intracranial haemorrhage
0.000 0.431 0.569
I63 Cerebral infarction
0.000 0.431 0.569
I47.2 Ventricular tachycardia
0.000 0.436 0.563
I67.7 Cerebral arteritis, not elsewhere classified
0.000 0.437 0.563
I67.6 Nonpyogenic thrombosis of intracranial venous system
0.000 0.437 0.563
I67.5 Moyamoya disease
0.000 0.437 0.563
I67.4 Hypertensive encephalopathy
0.000 0.437 0.563
I67.3 Progressive vascular leukoencephalopathy
0.000 0.437 0.563
I67.0 Dissection of cerebral arteries, nonruptured
0.000 0.437 0.563
I77.8 Other specified disorders of arteries and arterioles
0.000 0.438 0.562
I77.6 Arteritis, unspecified
0.000 0.438 0.562
I77.5 Necrosis of artery
0.000 0.438 0.562
I77.4 Coeliac artery compression syndrome
0.000 0.438 0.562
I77.3 Arterial fibromuscular dysplasia
0.000 0.438 0.562
I77.2 Rupture of artery
0.000 0.438 0.562
I77.0 Arteriovenous fistula, acquired
0.000 0.438 0.562
I52 Other heart disorders in diseases classified elsewhere
0.000 0.439 0.561
I48 Atrial fibrillation and flutter
0.000 0.439 0.561
I43 Cardiomyopathy in diseases classified elsewhere
0.000 0.439 0.561
I41 Myocarditis in diseases classified elsewhere
0.000 0.439 0.561
I40 Acute myocarditis
0.000 0.439 0.561
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.000 0.439 0.561
I37 Pulmonary valve disorders
0.000 0.439 0.561
I36 Nonrheumatic tricuspid valve disorders
0.000 0.439 0.561
I33 Acute and subacute endocarditis
0.000 0.439 0.561
I32 Pericarditis in diseases classified elsewhere
0.000 0.439 0.561
I98 Other disorders of circulatory system in diseases classified elsewhere
0.000 0.441 0.559
Z93.2 Ileostomy status
0.000 0.444 0.556
I95.9 Hypotension, unspecified
0.000 0.445 0.555
I71 Aortic aneurysm and dissection
0.000 0.445 0.555
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.448 0.551
I99 Other and unspecified disorders of circulatory system
0.000 0.448 0.551
E14 Unspecified diabetes mellitus
0.000 0.452 0.548
I51.8 Other ill-defined heart diseases
0.000 0.454 0.546
E86 Volume depletion
0.000 0.457 0.543
E07 Other disorders of thyroid
0.000 0.460 0.540
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.460 0.540
I74.5 Embolism and thrombosis of iliac artery
0.000 0.462 0.538
I35.0 Aortic (valve) stenosis
0.000 0.462 0.538
I30 Acute pericarditis
0.000 0.463 0.537
I42.9 Cardiomyopathy, unspecified
0.000 0.466 0.534
I09 Other rheumatic heart diseases
0.000 0.469 0.531
I06 Rheumatic aortic valve diseases
0.000 0.469 0.531
I05 Rheumatic mitral valve diseases
0.000 0.469 0.531
E83 Disorders of mineral metabolism
0.000 0.472 0.528
I74.9 Embolism and thrombosis of unspecified artery
0.000 0.472 0.528
I74.8 Embolism and thrombosis of other arteries
0.000 0.472 0.528
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.000 0.472 0.528
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.000 0.472 0.528
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.000 0.472 0.528
I74.0 Embolism and thrombosis of abdominal aorta
0.000 0.472 0.528
I69 Sequelae of cerebrovascular disease
0.000 0.474 0.526
I22.8 Subsequent myocardial infarction of other sites
0.000 0.475 0.525
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.475 0.525
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.475 0.525
E10.9 Without complications
0.000 0.476 0.524
E16 Other disorders of pancreatic internal secretion
0.000 0.485 0.515
I42.0 Dilated cardiomyopathy
0.000 0.485 0.515
I45.1 Other and unspecified right bundle-branch block
0.000 0.486 0.514
I23.8 Other current complications following acute myocardial infarction
0.000 0.486 0.514
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.000 0.486 0.514
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.000 0.486 0.514
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.000 0.486 0.514
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.000 0.486 0.514
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.000 0.486 0.514
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.000 0.486 0.514
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.000 0.486 0.514
I35.9 Aortic valve disorder, unspecified
0.000 0.486 0.513
I35.8 Other aortic valve disorders
0.000 0.486 0.513
I78.1 Naevus, nonneoplastic
0.000 0.486 0.513
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.487 0.513
E00 Congenital iodine-deficiency syndrome
0.000 0.487 0.513
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.487 0.513
I70.2 Atherosclerosis of arteries of the extremities
0.000 0.492 0.508
I28 Other diseases of pulmonary vessels
0.000 0.493 0.507
I12.9 Hypertensive renal disease without renal failure
0.000 0.494 0.506
I60.9 Subarachnoid haemorrhage, unspecified
0.000 0.496 0.504
I02 Rheumatic chorea
0.000 0.496 0.504
I01 Rheumatic fever with heart involvement
0.000 0.496 0.504
I00 Rheumatic fever without mention of heart involvement
0.000 0.496 0.504
I07 Rheumatic tricuspid valve diseases
0.000 0.498 0.501
E04 Other non-toxic goitre
0.000 0.499 0.501
E06 Thyroiditis
0.000 0.499 0.501
Z93.3 Colostomy status
0.000 0.499 0.501
I27.2 Other secondary pulmonary hypertension
0.000 0.502 0.498
I84.9 Unspecified haemorrhoids without complication
0.495 0.505 0.000
I78.9 Disease of capillaries, unspecified
0.000 0.506 0.494
I78.8 Other diseases of capillaries
0.000 0.506 0.494
I78.0 Hereditary haemorrhagic telangiectasia
0.000 0.506 0.494
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.459 0.508 0.034
I70.9 Generalised and unspecified atherosclerosis
0.000 0.508 0.492
I70.8 Atherosclerosis of other arteries
0.000 0.508 0.492
I70.1 Atherosclerosis of renal artery
0.000 0.508 0.492
I70.0 Atherosclerosis of aorta
0.000 0.508 0.492
E10.1 With ketoacidosis
0.000 0.511 0.489
Z98 Other postsurgical states
0.000 0.514 0.486
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.000 0.515 0.485
E87 Other disorders of fluid, electrolyte and acid-base balance
0.000 0.518 0.482
I31 Other diseases of pericardium
0.000 0.518 0.482
I84 Haemorrhoids
0.481 0.519 0.001
I72.9 Aneurysm of unspecified site
0.000 0.520 0.480
I72.8 Aneurysm of other specified arteries
0.000 0.520 0.480
I72.6 Aneurysm and dissection of vertebral artery
0.000 0.520 0.480
I72.5 Aneurysm and dissection of other precerebral arteries
0.000 0.520 0.480
I72.4 Aneurysm of artery of lower extremity
0.000 0.520 0.480
I72.3 Aneurysm of iliac artery
0.000 0.520 0.480
I72.2 Aneurysm of renal artery
0.000 0.520 0.480
I72.1 Aneurysm of artery of upper extremity
0.000 0.520 0.480
I72.0 Aneurysm of carotid artery
0.000 0.520 0.480
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.520 0.480
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.000 0.520 0.480
I79.1 Aortitis in diseases classified elsewhere
0.000 0.520 0.480
I79.0 Aneurysm of aorta in diseases classified elsewhere
0.000 0.520 0.480
E65-E68 Obesity and other hyperalimentation
0.000 0.523 0.477
Z97 Presence of other devices
0.000 0.524 0.476
I34.0 Mitral (valve) insufficiency
0.000 0.526 0.474
E15 Nondiabetic hypoglycaemic coma
0.000 0.527 0.472
E03.8 Other specified hypothyroidism
0.000 0.527 0.472
E03.5 Myxoedema coma
0.000 0.527 0.472
E03.4 Atrophy of thyroid (acquired)
0.000 0.527 0.472
E03.3 Postinfectious hypothyroidism
0.000 0.527 0.472
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.527 0.472
E03.1 Congenital hypothyroidism without goitre
0.000 0.527 0.472
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.527 0.472
I61.9 Intracerebral haemorrhage, unspecified
0.000 0.531 0.469
I60.8 Other subarachnoid haemorrhage
0.000 0.532 0.468
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified
0.000 0.532 0.468
I60.6 Subarachnoid haemorrhage from other intracranial arteries
0.000 0.532 0.468
I60.5 Subarachnoid haemorrhage from vertebral artery
0.000 0.532 0.468
I60.4 Subarachnoid haemorrhage from basilar artery
0.000 0.532 0.468
I60.3 Subarachnoid haemorrhage from posterior communicating artery
0.000 0.532 0.468
I60.2 Subarachnoid haemorrhage from anterior communicating artery
0.000 0.532 0.468
I60.1 Subarachnoid haemorrhage from middle cerebral artery
0.000 0.532 0.468
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation
0.000 0.532 0.468
Z82.3 Family history of stroke
0.000 0.533 0.466
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.538 0.462
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.000 0.538 0.462
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.538 0.462
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.538 0.462
I15.9 Seconday hypertension, unspecified
0.000 0.538 0.462
I15.8 Other secondary hypertension
0.000 0.538 0.462
I15.2 Hypertension secondary to endocrine disorders
0.000 0.538 0.462
I15.1 Hypertension secondary to other renal disorders
0.000 0.538 0.462
I15.0 Renovascular hypertension
0.000 0.538 0.462
E10.8 With unspecified complications
0.000 0.538 0.462
E10.7 With multiple complications
0.000 0.538 0.462
E10.6 With other specified complications
0.000 0.538 0.462
E10.5 With peripheral circulatory complications
0.000 0.538 0.462
E10.2 With renal complications
0.000 0.538 0.462
E10.0 With coma
0.000 0.538 0.462
I42.8 Other cardiomyopathies
0.000 0.540 0.460
I42.7 Cardiomyopathy due to drugs and other external agents
0.000 0.540 0.460
I42.6 Alcoholic cardiomyopathy
0.000 0.540 0.460
I42.5 Other restrictive cardiomyopathy
0.000 0.540 0.460
I42.4 Endocardial fibroelastosis
0.000 0.540 0.460
I42.3 Endomyocardial (eosinophilic) disease
0.000 0.540 0.460
I42.1 Obstructive hypertrophic cardiomyopathy
0.000 0.540 0.460
I47.0 Reentry ventricular arrhythmia
0.000 0.540 0.460
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.540 0.460
I84.5 External haemorrhoids without complication
0.458 0.542 0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.543 0.457
Z87 Personal history of other diseases and conditions
0.000 0.544 0.456
I46 Cardiac arrest
0.000 0.544 0.456
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.544 0.455
I61.8 Other intracerebral haemorrhage
0.000 0.547 0.453
I61.6 Intracerebral haemorrhage, multiple localised
0.000 0.547 0.453
I61.5 Intracerebral haemorrhage, intraventricular
0.000 0.547 0.453
I61.4 Intracerebral haemorrhage in cerebellum
0.000 0.547 0.453
I61.3 Intracerebral haemorrhage in brain stem
0.000 0.547 0.453
I61.2 Intracerebral haemorrhage in hemisphere, unspecified
0.000 0.547 0.453
I61.1 Intracerebral haemorrhage in hemisphere, cortical
0.000 0.547 0.453
I61.0 Intracerebral haemorrhage in hemisphere, subcortical
0.000 0.547 0.453
E88.9 Metabolic disorder, unspecified
0.000 0.547 0.453
E88.8 Other specified metabolic disorders
0.000 0.547 0.453
E88.3 Tumour lysis syndrome
0.000 0.547 0.453
E88.2 Lipomatosis, not elsewhere classified
0.000 0.547 0.453
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.547 0.453
I08.0 Disorders of both mitral and aortic valves
0.000 0.548 0.452
I50 Heart failure
0.000 0.549 0.451
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.552 0.448
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.552 0.448
E70.3 Albinism
0.000 0.552 0.448
E70.2 Disorders of tyrosine metabolism
0.000 0.552 0.448
E70.1 Other hyperphenylalaninaemias
0.000 0.552 0.448
E70.0 Classical phenylketonuria
0.000 0.552 0.448
E71.3 Disorders of fatty-acid metabolism
0.000 0.552 0.448
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.552 0.448
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.552 0.448
E71.0 Maple-syrup-urine disease
0.000 0.552 0.448
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.552 0.448
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.552 0.448
E72.5 Disorders of glycine metabolism
0.000 0.552 0.448
E72.4 Disorders of ornithine metabolism
0.000 0.552 0.448
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.552 0.448
E72.2 Disorders of urea cycle metabolism
0.000 0.552 0.448
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.552 0.448
E72.0 Disorders of amino-acid transport
0.000 0.552 0.448
E73.9 Lactose intolerance, unspecified
0.000 0.552 0.448
E73.8 Other lactose intolerance
0.000 0.552 0.448
E73.1 Secondary lactase deficiency
0.000 0.552 0.448
E73.0 Congenital lactase deficiency
0.000 0.552 0.448
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.552 0.448
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.552 0.448
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.552 0.448
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.552 0.448
E74.2 Disorders of galactose metabolism
0.000 0.552 0.448
E74.1 Disorders of fructose metabolism
0.000 0.552 0.448
E74.0 Glycogen storage disease
0.000 0.552 0.448
E75.6 Lipid storage disorder, unspecified
0.000 0.552 0.448
E75.5 Other lipid storage disorders
0.000 0.552 0.448
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.552 0.448
E75.3 Sphingolipidosis, unspecified
0.000 0.552 0.448
E75.2 Other sphingolipidosis
0.000 0.552 0.448
E75.1 Other gangliosidosis
0.000 0.552 0.448
E75.0 GM2 gangliosidosis
0.000 0.552 0.448
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.552 0.448
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.552 0.448
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.552 0.448
E76.2 Other mucopolysaccharidoses
0.000 0.552 0.448
E76.1 Mucopolysaccharidosis, type II
0.000 0.552 0.448
E76.0 Mucopolysaccharidosis, type I
0.000 0.552 0.448
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.552 0.448
E77.8 Other disorders of glycoprotein metabolism
0.000 0.552 0.448
E77.1 Defects in glycoprotein degradation
0.000 0.552 0.448
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.552 0.448
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.552 0.448
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.552 0.448
E79.1 Lesch-Nyhan syndrome
0.000 0.552 0.448
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.552 0.448
E84.9 Cystic fibrosis, unspecified
0.000 0.552 0.448
E84.8 Cystic fibrosis with other manifestations
0.000 0.552 0.448
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.552 0.448
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.552 0.448
E85.9 Amyloidosis, unspecified
0.000 0.552 0.448
E85.8 Other amyloidosis
0.000 0.552 0.448
E85.4 Organ-limited amyloidosis
0.000 0.552 0.448
E85.3 Secondary systemic amyloidosis
0.000 0.552 0.448
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.552 0.448
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.552 0.448
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.552 0.448
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.552 0.448
E80.6 Other disorders of bilirubin metabolism
0.000 0.552 0.448
E80.5 Crigler-Najjar syndrome
0.000 0.552 0.448
E80.3 Defects of catalase and peroxydase
0.000 0.552 0.448
E80.2 Other porphyria
0.000 0.552 0.448
E80.1 Porphyria cutanea tarda
0.000 0.552 0.448
E80.0 Hereditary erythropoietic porphyria
0.000 0.552 0.448
E80.4 Gilbert's syndrome
0.000 0.553 0.447
I47.1 Supraventricular tachycardia
0.000 0.553 0.447
I34.1 Mitral (valve) prolapse
0.000 0.554 0.446
I95.2 Hypotension due to drugs
0.000 0.554 0.446
I66.9 Occlusion and stenosis of unspecified cerebral artery
0.000 0.558 0.442
I66.8 Occlusion and stenosis of other cerebral artery
0.000 0.558 0.442
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries
0.000 0.558 0.442
I66.3 Occlusion and stenosis of cerebellar arteries
0.000 0.558 0.442
I66.2 Occlusion and stenosis of posterior cerebral artery
0.000 0.558 0.442
I66.1 Occlusion and stenosis of anterior cerebral artery
0.000 0.558 0.442
I66.0 Occlusion and stenosis of middle cerebral artery
0.000 0.558 0.442
I68.8 Other cerebrovascular disorders in diseases classified elsewhere
0.000 0.558 0.442
I68.2 Cerebral arteritis in other diseases classified elsewhere
0.000 0.558 0.442
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere
0.000 0.558 0.442
I68.0 Cerebral amyloid angiopathy
0.000 0.558 0.442
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.558 0.442
E46 Unspecified protein-energy malnutrition
0.000 0.558 0.442
E45 Retarded development following protein-energy malnutrition
0.000 0.558 0.442
E43 Unspecified severe protein-energy malnutrition
0.000 0.558 0.442
E42 Marasmic kwashiorkor
0.000 0.558 0.442
E41 Nutritional marasmus
0.000 0.558 0.442
E40 Kwashiorkor
0.000 0.558 0.442
E12.9 Without complications
0.000 0.558 0.442
E12.8 With unspecified complications
0.000 0.558 0.442
E12.7 With multiple complications
0.000 0.558 0.442
E12.6 With other specified complications
0.000 0.558 0.442
E12.5 With peripheral circulatory complications
0.000 0.558 0.442
E12.4 With neurological complications
0.000 0.558 0.442
E12.3 With ophthalmic complications
0.000 0.558 0.442
E12.2 With renal complications
0.000 0.558 0.442
E12.1 With ketoacidosis
0.000 0.558 0.442
E12.0 With coma
0.000 0.558 0.442
E13.9 Without complications
0.000 0.558 0.442
E13.8 With unspecified complications
0.000 0.558 0.442
E13.7 With multiple complications
0.000 0.558 0.442
E13.6 With other specified complications
0.000 0.558 0.442
E13.5 With peripheral circulatory complications
0.000 0.558 0.442
E13.4 With neurological complications
0.000 0.558 0.442
E13.3 With ophthalmic complications
0.000 0.558 0.442
E13.2 With renal complications
0.000 0.558 0.442
E13.1 With ketoacidosis
0.000 0.558 0.442
E13.0 With coma
0.000 0.558 0.442
I83 Varicose veins of lower extremities
0.432 0.561 0.007
I95.8 Other hypotension
0.000 0.561 0.439
I95.0 Idiopathic hypotension
0.000 0.561 0.439
E10.4 With neurological complications
0.000 0.562 0.438
Z98.1 Arthrodesis status
0.000 0.562 0.438
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.564 0.436
I51.6 Cardiovascular disease, unspecified
0.000 0.564 0.436
I51.5 Myocardial degeneration
0.000 0.564 0.436
I51.4 Myocarditis, unspecified
0.000 0.564 0.436
I51.3 Intracardiac thrombosis, not elsewhere classified
0.000 0.564 0.436
I51.2 Rupture of papillary muscle, not elsewhere classified
0.000 0.564 0.436
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.000 0.564 0.436
I51.0 Cardiac septal defect, acquired
0.000 0.564 0.436
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.000 0.564 0.436
I34.8 Other nonrheumatic mitral valve disorders
0.000 0.564 0.436
I34.2 Nonrheumatic mitral (valve) stenosis
0.000 0.564 0.436
I24.1 Dressler's syndrome
0.000 0.565 0.435
I84.4 External haemorrhoids with other complications
0.434 0.566 0.000
I11.0 Hypertensive heart disease with (congestive) heart failure
0.000 0.566 0.434
I51.9 Heart disease, unspecified
0.000 0.567 0.433
I77.9 Disorder of arteries and arterioles, unspecified
0.000 0.572 0.427
Z93.1 Gastrostomy status
0.000 0.572 0.428
Z82.8 Family history of other disabilities and chronic diseases leading to disablement, not elsewhere classified
0.000 0.573 0.426
Z82.7 Family history of congenital malformations, deformations and chromosomal abnormalities
0.000 0.573 0.426
Z82.6 Family history of arthritis and other diseases of the musculoskeletal system and connective tissue
0.000 0.573 0.426
Z82.5 Family history of asthma and other chronic lower respiratory diseases
0.000 0.573 0.426
Z82.2 Family history of deafness and hearing loss
0.000 0.573 0.426
Z82.1 Family history of blindness and visual loss
0.000 0.573 0.426
E20-E35 Disorders of other endocrine glands
0.001 0.574 0.426
Z94 Transplanted organ and tissue status
0.000 0.575 0.425
I47.9 Paroxysmal tachycardia, unspecified
0.000 0.576 0.423
E61 Deficiency of other nutrient elements
0.000 0.577 0.423
I08.9 Multiple valve disease, unspecified
0.000 0.577 0.423
I08.8 Other multiple valve diseases
0.000 0.577 0.423
I08.2 Disorders of both aortic and tricuspid valves
0.000 0.577 0.423
I45.9 Conduction disorder, unspecified
0.000 0.578 0.421
I45.8 Other specified conduction disorders
0.000 0.578 0.421
I45.4 Nonspecific intraventricular block
0.000 0.578 0.421
I45.3 Trifascicular block
0.000 0.578 0.421
I45.2 Bifascicular block
0.000 0.578 0.421
I45.0 Right fascicular block
0.000 0.578 0.421
Z84 Family history of other conditions
0.000 0.580 0.420
Z81 Family history of mental and behavioural disorders
0.000 0.580 0.420
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.580 0.420
E63 Other nutritional deficiencies
0.000 0.580 0.420
E56 Other vitamin deficiencies
0.000 0.580 0.420
E51 Thiamine deficiency
0.000 0.580 0.420
E50 Vitamin A deficiency
0.000 0.580 0.420
E60 Dietary zinc deficiency
0.000 0.580 0.420
E59 Dietary selenium deficiency
0.000 0.580 0.420
E58 Dietary calcium deficiency
0.000 0.580 0.420
E54 Ascorbic acid deficiency
0.000 0.580 0.420
E52 Niacin deficiency [pellagra]
0.000 0.580 0.420
I65.9 Occlusion and stenosis of unspecified precerebral artery
0.000 0.582 0.418
I65.8 Occlusion and stenosis of other precerebral artery
0.000 0.582 0.418
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries
0.000 0.582 0.418
I65.1 Occlusion and stenosis of basilar artery
0.000 0.582 0.418
I65.0 Occlusion and stenosis of vertebral artery
0.000 0.582 0.418
Z83 Family history of other specific disorders
0.000 0.583 0.417
Z93.0 Tracheostomy status
0.000 0.583 0.417
E07.9 Disorder of thyroid, unspecified
0.000 0.585 0.415
Z87.1 Personal history of diseases of the digestive system
0.000 0.586 0.414
I27.8 Other specified pulmonary heart diseases
0.000 0.587 0.413
I27.1 Kyphoscoliotic heart disease
0.000 0.587 0.413
E16.2 Hypoglycaemia, unspecified
0.000 0.588 0.412
Z93.9 Artificial opening status, unspecified
0.000 0.588 0.412
Z93.8 Other artificial opening status
0.000 0.588 0.412
Z93.5 Cystostomy status
0.000 0.588 0.412
Z93.4 Other artificial openings of gastro-intestinal tract status
0.000 0.588 0.412
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.000 0.589 0.411
E55 Vitamin D deficiency
0.000 0.590 0.410
I63.9 Cerebral infarction, unspecified
0.000 0.591 0.409
I98.2 Oesophageal varices in diseases classified elsewhere
0.000 0.591 0.409

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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