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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs116853542
log Bayes Factor = 17.1118
Chromosome 7   position 18,656,230  (GRCh37) Explore rs116853542 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
1.000 0.000 0.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.999 0.001 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.999 0.001 0.000
Z92 Personal history of medical treatment
0.998 0.002 0.000
E11 Non-insulin-dependent diabetes mellitus
0.997 0.003 0.000
I30-I52 Other forms of heart disease
0.996 0.004 0.000
E11.9 Without complications
0.995 0.005 0.000
E14 Unspecified diabetes mellitus
0.994 0.006 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.991 0.009 0.000
E14.9 Without complications
0.989 0.011 0.000
Z86 Personal history of certain other diseases
0.987 0.013 0.000
O60-O75 Complications of labour and delivery
0.986 0.014 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.984 0.016 0.000
E70-E90 Metabolic disorders
0.983 0.017 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.983 0.017 0.000
Z51 Other medical care
0.980 0.020 0.000
I20-I25 Ischaemic heart diseases
0.980 0.020 0.000
Z92.2 Personal history of long-term (current) use of other medicaments
0.978 0.022 0.000
Chapter XI Diseases of the digestive system
0.975 0.025 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.973 0.027 0.000
I20 Angina pectoris
0.967 0.033 0.000
E78.0 Pure hypercholesterolaemia
0.967 0.033 0.000
Z86.7 Personal history of diseases of the circulatory system
0.965 0.035 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.965 0.035 0.000
Z51.2 Other chemotherapy
0.955 0.045 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.954 0.046 0.000
K35-K38 Diseases of appendix
0.952 0.048 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.950 0.050 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.949 0.051 0.000
I20.0 Unstable angina
0.947 0.053 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.944 0.056 0.000
Chapter XX External causes of morbidity and mortality
0.944 0.056 0.000
C44 Other malignant neoplasms of skin
0.925 0.075 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.923 0.077 0.000
O72 Postpartum haemorrhage
0.923 0.077 0.000
C34 Malignant neoplasm of bronchus and lung
0.922 0.078 0.000
Z51.0 Radiotherapy session
0.922 0.078 0.000
K90-K93 Other diseases of the digestive system
0.920 0.080 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.919 0.081 0.000
M20-M25 Other joint disorders
0.918 0.082 0.000
Z92.3 Personal history of irradiation
0.913 0.087 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.911 0.089 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.908 0.092 0.000
I35 Nonrheumatic aortic valve disorders
0.901 0.099 0.000
I49 Other cardiac arrhythmias
0.901 0.099 0.000
Chapter X Diseases of the respiratory system
0.897 0.103 0.000
K35 Acute appendicitis
0.896 0.104 0.000
I80 Phlebitis and thrombophlebitis
0.895 0.105 0.000
Z92.6 Personal history of chemotherapy for neoplastic disease
0.887 0.113 0.000
Z86.4 Personal history of psychoactive substance abuse
0.885 0.115 0.000
C44.1 Skin of eyelid, including canthus
0.879 0.121 0.000
O36 Maternal care for other known or suspected foetal problems
0.877 0.123 0.000
Z53 Persons encountering health services for specifie procedures, not carried out
0.876 0.124 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.876 0.124 0.000
C78.0 Secondary malignant neoplasm of lung
0.875 0.125 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.867 0.133 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.862 0.138 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.861 0.139 0.000
I42 Cardiomyopathy
0.861 0.139 0.000
Z86.6 Personal history of diseases of the nervous system and sense organs
0.861 0.139 0.000
C64-C68 Malignant neoplasms of urinary tract
0.859 0.140 0.000
O72.1 Other immediate postpartum haemorrhage
0.859 0.141 0.000
K37 Unspecified appendicitis
0.859 0.141 0.000
C34.9 Bronchus or lung, unspecified
0.855 0.145 0.000
K70-K77 Diseases of liver
0.852 0.148 0.000
I05-I09 Chronic rheumatic heart diseases
0.849 0.151 0.000
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities
0.849 0.151 0.000
M05-M14 Inflammatory polyarthropathies
0.848 0.152 0.000
M20 Acquired deformities of fingers and toes
0.848 0.152 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.846 0.154 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.846 0.154 0.000
M45-M49 Spondylopathies
0.846 0.154 0.000
K35.9 Acute appendicitis, unspecified
0.846 0.154 0.000
I34 Nonrheumatic mitral valve disorders
0.844 0.156 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.844 0.156 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.844 0.156 0.000
Z51.5 Palliative care
0.842 0.158 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.841 0.159 0.000
I49.9 Cardiac arrhythmia, unspecified
0.841 0.159 0.000
K92 Other diseases of digestive system
0.839 0.161 0.000
Z92.1 Personal history of long-term (current) use of anticoagulants
0.839 0.161 0.000
I47 Paroxysmal tachycardia
0.838 0.162 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.836 0.164 0.000
C79 Secondary malignant neoplasm of other sites
0.832 0.168 0.000
O70 Perineal laceration during delivery
0.830 0.170 0.000
I51 Complications and ill-defined descriptions of heart disease
0.830 0.170 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.829 0.171 0.000
E88 Other metabolic disorders
0.827 0.173 0.000
Y95 Nosocomial condition
0.827 0.173 0.000
I20.9 Angina pectoris, unspecified
0.825 0.175 0.000
M65-M68 Disorders of synovium and tendon
0.823 0.177 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.822 0.178 0.000
Z51.1 Chemotherapy session for neoplasm
0.821 0.179 0.000
L90 Atrophic disorders of skin
0.820 0.180 0.000
C78.7 Secondary malignant neoplasm of liver
0.815 0.184 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.814 0.186 0.000
J09-J18 Influenza and pneumonia
0.814 0.186 0.000
C51-C58 Malignant neoplasms of female genital organs
0.812 0.188 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.811 0.189 0.000
Z40 Prophylactic surgery
0.808 0.192 0.000
O16 Unspecified maternal hypertension
0.807 0.193 0.000
D70 Agranulocytosis
0.807 0.193 0.000
Z43 Attention to artificial openings
0.805 0.195 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.804 0.196 0.000
C44.4 Skin of scalp and neck
0.802 0.198 0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria
0.801 0.199 0.000
I35.0 Aortic (valve) stenosis
0.799 0.201 0.000
O63 Long labour
0.797 0.203 0.000
Z53.0 Procedure not carried out because of contraindication
0.797 0.203 0.000
C43 Malignant melanoma of skin
0.791 0.208 0.000
O42 Premature rupture of membranes
0.791 0.208 0.000
Chapter XXII Codes for special purposes
0.790 0.210 0.000
L90.5 Scar conditions and fibrosis of skin
0.787 0.213 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.787 0.213 0.000
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities
0.786 0.214 0.000
L03 Cellulitis
0.784 0.216 0.000
Z86.2 Personal history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.782 0.218 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.780 0.220 0.000
E20-E35 Disorders of other endocrine glands
0.780 0.220 0.000
Z92.0 Personal history of contraception
0.780 0.220 0.000
Z95.5 Presence of coronary angioplasty implant and graft
0.778 0.222 0.000
C44.7 Skin of lower limb, including hip
0.778 0.222 0.000
O61 Failed induction of labour
0.777 0.223 0.000
Z93 Artificial opening status
0.777 0.223 0.000
C34.1 Upper lobe, bronchus or lung
0.777 0.223 0.000
J20-J22 Other acute lower respiratory infections
0.776 0.224 0.000
I46 Cardiac arrest
0.774 0.226 0.000
O00-O08 Pregnancy with abortive outcome
0.774 0.226 0.000
I51.7 Cardiomegaly
0.772 0.228 0.000
C44.6 Skin of upper limb, including shoulder
0.771 0.229 0.000
I50 Heart failure
0.770 0.230 0.000
E11.2 With renal complications
0.769 0.231 0.000
M70-M79 Other soft tissue disorders
0.766 0.234 0.000
I20.1 Angina pectoris with documented spasm
0.766 0.234 0.000
L02.4 Cutaneous abscess, furuncle and carbuncle of limb
0.762 0.238 0.000
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified
0.762 0.238 0.000
Z53.9 Procedure not carried out, unspecified reason
0.761 0.239 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.761 0.239 0.000
M35 Other systemic involvement of connective tissue
0.760 0.240 0.000
O36.5 Maternal care for poor foetal growth
0.760 0.240 0.000
Z41 Procedures for purposes other than remedying health state
0.758 0.242 0.000
C80 Malignant neoplasm without specification of site
0.758 0.242 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.758 0.242 0.000
Z89 Acquired absence of limb
0.756 0.244 0.000
I34.0 Mitral (valve) insufficiency
0.756 0.244 0.000
C34.2 Middle lobe, bronchus or lung
0.756 0.244 0.000
C15-C26 Malignant neoplasms of digestive organs
0.754 0.246 0.000
D00-D09 In situ neoplasms
0.754 0.246 0.000
K04 Diseases of pulp and periapical tissues
0.754 0.246 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.753 0.246 0.000
C78.2 Secondary malignant neoplasm of pleura
0.752 0.248 0.000
K92.2 Gastro-intestinal haemorrhage, unspecified
0.751 0.249 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.750 0.250 0.000
M06 Other rheumatoid arthritis
0.750 0.250 0.000
I42.9 Cardiomyopathy, unspecified
0.749 0.251 0.000
O36.8 Maternal care for other specified foetal problems
0.747 0.253 0.000
O73 Retained placenta and membranes, without haemorrhage
0.747 0.253 0.000
Z50 Care involving use of rehabilitation procedures
0.745 0.255 0.000
M47 Spondylosis
0.744 0.256 0.000
K55-K64 Other diseases of intestines
0.744 0.256 0.000
K90 Intestinal malabsorption
0.742 0.258 0.000
I85 Oesophageal varices
0.741 0.259 0.000
I38 Endocarditis, valve unspecified
0.741 0.259 0.000
I35.9 Aortic valve disorder, unspecified
0.741 0.259 0.000
O70.1 Second degree perineal laceration during delivery
0.741 0.259 0.000
Chapter V Mental and behavioural disorders
0.741 0.259 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.739 0.261 0.000
D60-D64 Aplastic and other anaemias
0.738 0.262 0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.737 0.263 0.000
O62 Abnormalities of forces of labour
0.736 0.264 0.000
I21 Acute myocardial infarction
0.736 0.264 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.736 0.264 0.000
O72.2 Delayed and secondary postpartum haemorrhage
0.735 0.265 0.000
E50-E64 Other nutritional deficiencies
0.735 0.265 0.000
K65-K67 Diseases of peritoneum
0.734 0.266 0.000
K38 Other diseases of appendix
0.733 0.267 0.000
C45 Mesothelioma
0.732 0.268 0.000
Z97 Presence of other devices
0.731 0.269 0.000
K35.8 Acute appendicitis, other and unspecified
0.731 0.269 0.000
I31 Other diseases of pericardium
0.731 0.269 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.731 0.269 0.000
E11.5 With peripheral circulatory complications
0.730 0.270 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.729 0.271 0.000
Z42 Follow-up care involving plastic surgery
0.729 0.271 0.000
Z91.0 Personal history of allergy, other than to drugs and biological substances
0.729 0.271 0.000
X60-X84 Intentional self-harm
0.729 0.271 0.000
M50-M54 Other dorsopathies
0.728 0.272 0.000
Z86.3 Personal history of endocrine, nutritional and metabolic diseases
0.728 0.272 0.000
M40-M43 Deforming dorsopathies
0.728 0.272 0.000
J00-J06 Acute upper respiratory infections
0.727 0.273 0.000
K74 Fibrosis and cirrhosis of liver
0.727 0.273 0.000
Z08 Follow-up examination after treatment for malignant neoplasm
0.725 0.275 0.000
E11.4 With neurological complications
0.725 0.275 0.000
O80-O84 Delivery
0.722 0.277 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.722 0.278 0.000
I22 Subsequent myocardial infarction
0.721 0.279 0.000
I49.8 Other specified cardiac arrhythmias
0.721 0.279 0.000
O48 Prolonged pregnancy
0.720 0.280 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.719 0.281 0.000
W00-W19 Falls
0.718 0.282 0.000
E14.3 With ophthalmic complications
0.718 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.717 0.283 0.000
E40-E46 Malnutrition
0.717 0.283 0.000
E13 Other specified diabetes mellitus
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.717 0.283 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.717 0.283 0.000
O85-O92 Complications predominantly related to the puerperium
0.716 0.283 0.000
Z84 Family history of other conditions
0.716 0.284 0.000
Z81 Family history of mental and behavioural disorders
0.716 0.284 0.000
Z04 Examination and observation for other reasons
0.716 0.284 0.000
Z90.7 Acquired absence of genital organ(s)
0.716 0.284 0.000
I60-I69 Cerebrovascular diseases
0.716 0.284 0.000
J90-J94 Other diseases of pleura
0.716 0.284 0.000
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.715 0.284 0.000
Z90.1 Acquired absence of breast(s)
0.715 0.285 0.000
Z92.9 Personal history of medical treatment, unspecified
0.715 0.285 0.000
Z92.8 Personal history of other medical treatment
0.715 0.285 0.000
Z92.5 Personal history of rehabilitation measures
0.715 0.285 0.000
E11.8 With unspecified complications
0.715 0.285 0.000
E11.7 With multiple complications
0.715 0.285 0.000
E11.6 With other specified complications
0.715 0.285 0.000
E11.1 With ketoacidosis
0.715 0.285 0.000
E11.0 With coma
0.715 0.285 0.000
I52 Other heart disorders in diseases classified elsewhere
0.714 0.285 0.000
I48 Atrial fibrillation and flutter
0.714 0.285 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.714 0.285 0.000
I41 Myocarditis in diseases classified elsewhere
0.714 0.285 0.000
I40 Acute myocarditis
0.714 0.285 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.714 0.285 0.000
I37 Pulmonary valve disorders
0.714 0.285 0.000
I36 Nonrheumatic tricuspid valve disorders
0.714 0.285 0.000
I33 Acute and subacute endocarditis
0.714 0.285 0.000
I32 Pericarditis in diseases classified elsewhere
0.714 0.285 0.000
I30 Acute pericarditis
0.714 0.285 0.000
M20.4 Other hammer toe(s) (acquired)
0.713 0.287 0.000
I80.9 Phlebitis and thrombophlebitis of unspecified site
0.713 0.287 0.000
E14.8 With unspecified complications
0.712 0.288 0.000
E14.7 With multiple complications
0.712 0.288 0.000
E14.6 With other specified complications
0.712 0.288 0.000
E14.5 With peripheral circulatory complications
0.712 0.288 0.000
E14.4 With neurological complications
0.712 0.288 0.000
E14.2 Withrenal complications
0.712 0.288 0.000
E14.1 With ketoacidosis
0.712 0.288 0.000
E14.0 With coma
0.712 0.288 0.000
Chapter VIII Diseases of the ear and mastoid process
0.712 0.288 0.000
M20.2 Hallux rigidus
0.712 0.288 0.000
K58 Irritable bowel syndrome
0.711 0.289 0.000
Z54 Convalescence
0.710 0.290 0.000
Z52 Donors of organs and tissues
0.710 0.290 0.000
Z49 Care involving dialysis
0.710 0.290 0.000
Z44 Fitting and adjustment of external prosthetic device
0.710 0.290 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.708 0.292 0.000
O74 Complications of anaesthesia during labour and delivery
0.707 0.293 0.000
O71 Other obstetric trauma
0.707 0.293 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.707 0.293 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.707 0.293 0.000
O66 Other obstructed labour
0.707 0.293 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.707 0.293 0.000
O60 Preterm delivery
0.707 0.293 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.707 0.293 0.000
J95-J99 Other diseases of the respiratory system
0.706 0.294 0.000
L08 Other local infections of skin and subcutaneous tissue
0.706 0.294 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.705 0.295 0.000
I42.2 Other hypertrophic cardiomyopathy
0.705 0.295 0.000
E85 Amyloidosis
0.705 0.295 0.000
E84 Cystic fibrosis
0.705 0.295 0.000
E79 Disorders of purine and pyrimidine metabolism
0.705 0.295 0.000
E77 Disorders of glycoprotein metabolism
0.705 0.295 0.000
E76 Disorders of glycosaminoglycan metabolism
0.705 0.295 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.705 0.295 0.000
E74 Other disorders of carbohydrate metabolism
0.705 0.295 0.000
E73 Lactose intolerance
0.705 0.295 0.000
E72 Other disorders of amino-acid metabolism
0.705 0.295 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.705 0.295 0.000
E70 Disorders of aromatic amino-acid metabolism
0.705 0.295 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.705 0.295 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.704 0.295 0.000
M91-M94 Chondropathies
0.704 0.295 0.000
M86-M90 Other osteopathies
0.704 0.295 0.000
M60-M63 Disorders of muscles
0.704 0.295 0.000
M00-M03 Infectious arthropathies
0.704 0.295 0.000
Z92.4 Personal history of major surgery, not elsewhere classified
0.704 0.296 0.000
Z51.9 Medical care, unspecified
0.703 0.297 0.000
Z51.6 Desensitisation to allergens
0.703 0.297 0.000
I23 Certain current complications following acute myocardial infarction
0.702 0.297 0.000
M67 Other disorders of synovium and tendon
0.701 0.299 0.000
Y43 Primarily systemic agents
0.700 0.300 0.000
Z98 Other postsurgical states
0.699 0.301 0.000
Z47 Other orthopaedic follow-up care
0.699 0.301 0.000
E78.9 Disorder of lipoprotein metabolism, unspecified
0.697 0.302 0.000
E78.8 Other disorders of lipoprotein metabolism
0.697 0.302 0.000
E78.6 Lipoprotein deficiency
0.697 0.302 0.000
E78.4 Other hyperlipidaemia
0.697 0.302 0.000
E78.3 Hyperchylomicronaemia
0.697 0.302 0.000
E78.2 Mixed hyperlipidaemia
0.697 0.302 0.000
E78.1 Pure hyperglyceridaemia
0.697 0.302 0.000
Z94 Transplanted organ and tissue status
0.697 0.303 0.000
J18 Pneumonia, organism unspecified
0.696 0.304 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.696 0.304 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.692 0.307 0.000
C50-C50 Malignant neoplasm of breast
0.692 0.308 0.000
K11 Diseases of salivary glands
0.692 0.308 0.000
M22 Disorders of patella
0.691 0.309 0.000
M80-M85 Disorders of bone density and structure
0.690 0.310 0.000
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk
0.690 0.310 0.000
D80-D89 Certain disorders involving the immune mechanism
0.690 0.310 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.690 0.310 0.000
J22 Unspecified acute lower respiratory infection
0.689 0.311 0.000
M20.6 Acquired deformity of toe(s), unspecified
0.688 0.312 0.000
K58.9 Irritable bowel syndrome without diarrhoea
0.688 0.312 0.000
I08 Multiple valve diseases
0.687 0.313 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.687 0.313 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.684 0.316 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.684 0.316 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.684 0.316 0.000
C32 Malignant neoplasm of larynx
0.684 0.316 0.000
C31 Malignant neoplasm of accessory sinuses
0.684 0.316 0.000
C30 Malignant neoplasm of nasal cavity and middle ear
0.684 0.316 0.000
C37 Malignant neoplasm of thymus
0.684 0.316 0.000
C33 Malignant neoplasm of trachea
0.684 0.316 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.683 0.317 0.000
E87.6 Hypokalaemia
0.683 0.317 0.000
K36 Other appendicitis
0.683 0.317 0.000
O45 Premature separation of placenta [abruptio placentae]
0.681 0.318 0.000
O44 Placenta praevia
0.681 0.318 0.000
O43 Placental disorders
0.681 0.318 0.000
O41 Other disorders of amniotic fluid and membranes
0.681 0.318 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.681 0.318 0.000
O33 Maternal care for known or suspected disproportion
0.681 0.318 0.000
O31 Complications specific to multiple gestation
0.681 0.318 0.000
O30 Multiple gestation
0.681 0.318 0.000
O40 Polyhydramnios
0.681 0.318 0.000
K76 Other diseases of liver
0.681 0.319 0.000
L10-L14 Bullous disorders
0.680 0.320 0.000
Z85 Personal history of malignant neoplasm
0.680 0.320 0.000
M06.9 Rheumatoid arthritis, unspecified
0.679 0.321 0.000
I47.1 Supraventricular tachycardia
0.679 0.321 0.000
Z11 Special screening examination for infectious and parasitic diseases
0.679 0.321 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.678 0.322 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.677 0.323 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.677 0.323 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.677 0.323 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.677 0.323 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.677 0.323 0.000
Y35-Y36 Legal intervention and operations of war
0.677 0.323 0.000
Y10-Y34 Event of undetermined intent
0.677 0.323 0.000
Y00-Y09 Assault
0.677 0.323 0.000
X85-X99 Assault
0.677 0.323 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.677 0.323 0.000
X50-X57 Overexertion, travel and privation
0.677 0.323 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.677 0.323 0.000
X30-X39 Exposure to forces of nature
0.677 0.323 0.000
X20-X29 Contact with venomous animals and plants
0.677 0.323 0.000
X10-X19 Contact with heat and hot substances
0.677 0.323 0.000
X00-X09 Exposure to smoke, fire and flames
0.677 0.323 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.677 0.323 0.000
W75-W84 Other accidental threats to breathing
0.677 0.323 0.000
W65-W74 Accidental drowning and submersion
0.677 0.323 0.000
W50-W64 Exposure to animate mechanical forces
0.677 0.323 0.000
V98-V99 Other and unspecified transport accidents
0.677 0.323 0.000
V95-V97 Air and space transport accidents
0.677 0.323 0.000
V90-V94 Water transport accidents
0.677 0.323 0.000
V80-V89 Other land transport accidents
0.677 0.323 0.000
V70-V79 Bus occupant injured in transport accident
0.677 0.323 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.677 0.323 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.677 0.323 0.000
V40-V49 Car occupant injured in transport accident
0.677 0.323 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.677 0.323 0.000
V20-V29 Motorcycle rider injured in transport accident
0.677 0.323 0.000
V01-V09 Pedestrian injured in transport accident
0.677 0.323 0.000
Z40.0 Prophylactic surgery for risk-factors related to malignant neoplasms
0.676 0.324 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.676 0.324 0.000
M20.0 Deformity of finger(s)
0.675 0.324 0.000
C43.7 Malignant melanoma of lower limb, including hip
0.674 0.326 0.000
M23 Internal derangement of knee
0.674 0.326 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.674 0.326 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.672 0.328 0.000
C79.2 Secondary malignant neoplasm of skin
0.670 0.330 0.000
I47.2 Ventricular tachycardia
0.668 0.332 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.668 0.332 0.000
C44.2 Skin of ear and external auricular canal
0.668 0.332 0.000
Z08.0 Follow-up examination after surgery for malignant neoplasm
0.667 0.333 0.000
M10 Gout
0.667 0.333 0.000
C34.3 Lower lobe, bronchus or lung
0.666 0.334 0.000
I05 Rheumatic mitral valve diseases
0.664 0.335 0.000
K12 Stomatitis and related lesions
0.664 0.336 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.664 0.336 0.000
I49.5 Sick sinus syndrome
0.664 0.336 0.000
Z86.1 Personal history of infectious and parasitic diseases
0.664 0.336 0.000
C44.9 Malignant neoplasm of skin, unspecified
0.663 0.337 0.000
C44.8 Overlapping lesion of skin
0.663 0.337 0.000
O36.0 Maternal care for rhesus isoimmunisation
0.663 0.337 0.000
C67 Malignant neoplasm of bladder
0.662 0.338 0.000
C56 Malignant neoplasm of ovary
0.662 0.338 0.000
O15 Eclampsia
0.662 0.338 0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria
0.662 0.338 0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension
0.662 0.338 0.000
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium
0.662 0.338 0.000
O11 Pre-existing hypertensive disorder with superimposed proteinuria
0.662 0.338 0.000
I35.1 Aortic (valve) insufficiency
0.662 0.338 0.000
O72.3 Postpartum coagulation defects
0.661 0.338 0.000
O72.0 Third-stage haemorrhage
0.661 0.338 0.000
K07 Dentofacial anomalies [including malocclusion]
0.661 0.339 0.000
E78.5 Hyperlipidaemia, unspecified
0.661 0.339 0.000
C34.8 Overlapping lesion of bronchus and lung
0.661 0.339 0.000
C34.0 Main bronchus
0.661 0.339 0.000
I20.8 Other forms of angina pectoris
0.660 0.340 0.000
J60-J70 Lung diseases due to external agents
0.660 0.340 0.000
O47 False labour
0.660 0.340 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.660 0.340 0.000
D55-D59 Haemolytic anaemias
0.659 0.341 0.000
Z95.8 Presence of other cardiac and vascular implants and grafts
0.659 0.341 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.658 0.342 0.000
M34 Systemic sclerosis
0.658 0.342 0.000
M33 Dermatopolymyositis
0.658 0.342 0.000
M32 Systemic lupus erythematosus
0.658 0.342 0.000
M30 Polyarteritis nodosa and related conditions
0.658 0.342 0.000
M21 Other acquired deformities of limbs
0.658 0.342 0.000
K92.1 Melaena
0.658 0.342 0.000
L03.1 Cellulitis of other parts of limb
0.658 0.342 0.000
I46.0 Cardiac arrest with successful resuscitation
0.657 0.343 0.000
I24 Other acute ischaemic heart diseases
0.656 0.344 0.000
M05 Seropositive rheumatoid arthritis
0.656 0.344 0.000
M31 Other necrotising vasculopathies
0.655 0.345 0.000
K75 Other inflammatory liver diseases
0.654 0.346 0.000
L05 Pilonidal cyst
0.653 0.347 0.000
L04 Acute lymphadenitis
0.653 0.347 0.000
L01 Impetigo
0.653 0.347 0.000
L00 Staphylococcal scalded skin syndrome
0.653 0.347 0.000
W20-W49 Exposure to inanimate mechanical forces
0.652 0.348 0.000
V10-V19 Pedal cyclist injured in transport accident
0.651 0.349 0.000
I88 Nonspecific lymphadenitis
0.651 0.349 0.000
I87 Other disorders of veins
0.651 0.349 0.000
I86 Varicose veins of other sites
0.651 0.349 0.000
I82 Other venous embolism and thrombosis
0.651 0.349 0.000
I81 Portal vein thrombosis
0.651 0.349 0.000
I25 Chronic ischaemic heart disease
0.650 0.350 0.000
I27 Other pulmonary heart diseases
0.650 0.350 0.000
I44 Atrioventricular and left bundle-branch block
0.650 0.350 0.000
O63.9 Long labour, unspecified
0.649 0.350 0.000
O75.7 Vaginal delivery following previous Caesarean section
0.649 0.351 0.000
C77.1 Intrathoracic lymph nodes
0.648 0.352 0.000
L50-L54 Urticaria and erythema
0.647 0.353 0.000
Z90.8 Acquired absence of other organs
0.646 0.354 0.000
I35.8 Other aortic valve disorders
0.646 0.354 0.000
I49.4 Other and unspecified premature depolarisation
0.646 0.354 0.000
I49.2 Junctional premature depolarisation
0.646 0.354 0.000
I49.1 Atrial premature depolarisation
0.646 0.354 0.000
D73 Diseases of spleen
0.646 0.354 0.000
E10 Insulin-dependent diabetes mellitus
0.643 0.356 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.643 0.356 0.000
K04.7 Periapical abscess without sinus
0.643 0.357 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.643 0.357 0.000
K35.3 Acute appendicitis with localized peritonitis
0.642 0.358 0.000
K35.2 Acute appendicitis with generalized peritonitis
0.642 0.358 0.000
K35.1 Acute appendicitis with peritoneal abscess
0.642 0.358 0.000
Z13 Special screening examination for other diseases and disorders
0.642 0.358 0.000
D72 Other disorders of white blood cells
0.642 0.358 0.000
I07 Rheumatic tricuspid valve diseases
0.642 0.358 0.000
I80.8 Phlebitis and thrombophlebitis of other sites
0.642 0.358 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.641 0.359 0.000
D62 Acute posthaemorrhagic anaemia
0.641 0.359 0.000
L03.8 Cellulitis of other sites
0.641 0.359 0.000
M48 Other spondylopathies
0.640 0.360 0.000
I50.0 Congestive heart failure
0.638 0.362 0.000
L84 Corns and callosities
0.638 0.362 0.000
Z91.6 Personal history of other physical trauma
0.637 0.363 0.000
Chapter XIV Diseases of the genitourinary system
0.636 0.364 0.000
L03.9 Cellulitis, unspecified
0.636 0.364 0.000
Z95.1 Presence of aortocoronary bypass graft
0.636 0.364 0.000
K74.6 Other and unspecified cirrhosis of liver
0.634 0.366 0.000
O75.6 Delayed delivery after spontaneous or unspecified rupture of membranes
0.634 0.366 0.000
K04.5 Chronic apical periodontitis
0.634 0.366 0.000
C44.5 Skin of trunk
0.634 0.366 0.000
I45 Other conduction disorders
0.632 0.368 0.000
Chapter VI Diseases of the nervous system
0.632 0.368 0.000
K92.9 Disease of digestive system, unspecified
0.631 0.369 0.000
Z93.2 Ileostomy status
0.630 0.370 0.000
J00 Acute nasopharyngitis [common cold]
0.629 0.371 0.000
D75 Other diseases of blood and blood-forming organs
0.629 0.371 0.000
O36.9 Maternal care for foetal problem, unspecified
0.629 0.371 0.000
O36.7 Maternal care for viable foetus in abdominal pregnancy
0.629 0.371 0.000
O36.6 Maternal care for excessive foetal growth
0.629 0.371 0.000
O36.4 Maternal care for intra-uterine death
0.629 0.371 0.000
O36.3 Maternal care for signs of foetal hypoxia
0.629 0.371 0.000
O36.2 Maternal care for hydrops foetalis
0.629 0.371 0.000
O36.1 Maternal care for other isoimmunisation
0.629 0.371 0.000
K02 Dental caries
0.628 0.372 0.000
Z53.1 Procedure not carried out because of patient's decision for reasons of belief or group pressure
0.628 0.372 0.000
Y40 Systemic antibiotics
0.628 0.372 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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