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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs116894699
log Bayes Factor = 14.9995
Chromosome 7   position 117,002,834  (GRCh37) Explore rs116894699 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XIV Diseases of the genitourinary system
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
N20-N23 Urolithiasis
0.999 0.001 0.000
N20 Calculus of kidney and ureter
0.999 0.001 0.000
N40-N51 Diseases of male genital organs
0.996 0.004 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.994 0.006 0.000
Chapter V Mental and behavioural disorders
0.994 0.006 0.000
N20.0 Calculus of kidney
0.990 0.010 0.000
Chapter XXI Factors influencing health status and contact with health services
0.986 0.014 0.000
N42 Other disorders of prostate
0.984 0.016 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.981 0.019 0.000
I30-I52 Other forms of heart disease
0.979 0.021 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.978 0.022 0.000
S70-S79 Injuries to the hip and thigh
0.974 0.026 0.000
I60-I69 Cerebrovascular diseases
0.970 0.030 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.969 0.031 0.000
N20.1 Calculus of ureter
0.968 0.032 0.000
F41 Other anxiety disorders
0.967 0.033 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.961 0.039 0.000
F41.9 Anxiety disorder, unspecified
0.960 0.040 0.000
Chapter VI Diseases of the nervous system
0.959 0.041 0.000
Z50 Care involving use of rehabilitation procedures
0.958 0.042 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.955 0.045 0.000
N10-N16 Renal tubulo-interstitial diseases
0.954 0.046 0.000
F30-F39 Mood [affective] disorders
0.948 0.052 0.000
N42.9 Disorder of prostate, unspecified
0.946 0.054 0.000
N20.2 Calculus of kidney with calculus of ureter
0.936 0.064 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.935 0.065 0.000
I45 Other conduction disorders
0.933 0.067 0.000
I63 Cerebral infarction
0.932 0.068 0.000
G20-G26 Extrapyramidal and movement disorders
0.929 0.071 0.000
N13 Obstructive and reflux uropathy
0.928 0.072 0.000
N41 Inflammatory diseases of prostate
0.925 0.075 0.000
Chapter XX External causes of morbidity and mortality
0.924 0.076 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.924 0.076 0.000
N48 Other disorders of penis
0.923 0.077 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.923 0.077 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.920 0.080 0.000
S72 Fracture of femur
0.920 0.080 0.000
Z08 Follow-up examination after treatment for malignant neoplasm
0.913 0.087 0.000
Z50.9 Care involving use of rehabilitation procedure, unspecified
0.912 0.088 0.000
N42.8 Other specified disorders of prostate
0.912 0.088 0.000
S90-S99 Injuries to the ankle and foot
0.910 0.090 0.000
Chapter VIII Diseases of the ear and mastoid process
0.908 0.092 0.000
I77 Other disorders of arteries and arterioles
0.905 0.095 0.000
Z08.0 Follow-up examination after surgery for malignant neoplasm
0.900 0.100 0.000
N00-N08 Glomerular diseases
0.898 0.102 0.000
Z43 Attention to artificial openings
0.895 0.105 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.895 0.105 0.000
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified
0.895 0.105 0.000
N99-N99 Other disorders of the genitourinary system
0.895 0.105 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.892 0.108 0.000
T43.2 Other and unspecified antidepressants
0.892 0.108 0.000
T51 Toxic effect of alcohol
0.889 0.111 0.000
G20 Parkinson's disease
0.887 0.113 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.884 0.116 0.000
N41.1 Chronic prostatitis
0.880 0.120 0.000
M80-M85 Disorders of bone density and structure
0.872 0.128 0.000
S50-S59 Injuries to the elbow and forearm
0.872 0.128 0.000
I72 Other aneurysm
0.869 0.131 0.000
Z40 Prophylactic surgery
0.866 0.134 0.000
I63.9 Cerebral infarction, unspecified
0.862 0.138 0.000
T66-T78 Other and unspecified effects of external causes
0.861 0.139 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.857 0.143 0.000
I10-I15 Hypertensive diseases
0.857 0.143 0.000
I60 Subarachnoid haemorrhage
0.854 0.146 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.854 0.146 0.000
R29.6 Tendency to fall, not elsewhere classified
0.853 0.147 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.853 0.147 0.000
Chapter VII Diseases of the eye and adnexa
0.851 0.149 0.000
S10-S19 Injuries to the neck
0.847 0.153 0.000
H90-H95 Other disorders of ear
0.846 0.154 0.000
S72.0 Fracture of neck of femur
0.845 0.155 0.000
Z50.5 Speech therapy
0.844 0.156 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.843 0.157 0.000
Z12 Special screening examination for neoplasms
0.843 0.157 0.000
S92 Fracture of foot, except ankle
0.842 0.158 0.000
Z43.2 Attention to ileostomy
0.838 0.162 0.000
I51 Complications and ill-defined descriptions of heart disease
0.835 0.165 0.000
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
0.834 0.166 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.831 0.169 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.830 0.170 0.000
I45.9 Conduction disorder, unspecified
0.830 0.170 0.000
I47 Paroxysmal tachycardia
0.827 0.173 0.000
S76 Injury of muscle and tendon at hip and thigh level
0.827 0.173 0.000
I45.1 Other and unspecified right bundle-branch block
0.824 0.176 0.000
M05-M14 Inflammatory polyarthropathies
0.823 0.177 0.000
I71 Aortic aneurysm and dissection
0.821 0.179 0.000
M86-M90 Other osteopathies
0.820 0.180 0.000
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified
0.819 0.181 0.000
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified
0.819 0.181 0.000
F32 Depressive episode
0.814 0.186 0.000
Chapter II Neoplasms
0.813 0.187 0.000
I20-I25 Ischaemic heart diseases
0.813 0.187 0.000
H25-H28 Disorders of lens
0.813 0.187 0.000
S80-S89 Injuries to the knee and lower leg
0.812 0.188 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.810 0.190 0.000
F31 Bipolar affective disorder
0.810 0.190 0.000
N13.3 Other and unspecified hydronephrosis
0.810 0.190 0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.808 0.192 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.807 0.193 0.000
G25 Other extrapyramidal and movement disorders
0.804 0.196 0.000
I46 Cardiac arrest
0.804 0.196 0.000
N02 Recurrent and persistent haematuria
0.803 0.197 0.000
N42.2 Atrophy of prostate
0.801 0.199 0.000
T51.0 Ethanol
0.800 0.200 0.000
Z02 Examination and encounter for administrative purposes
0.800 0.200 0.000
F33 Recurrent depressive disorder
0.799 0.201 0.000
R26 Abnormalities of gait and mobility
0.798 0.202 0.000
N48.6 Balanitis xerotica obliterans
0.798 0.202 0.000
Z40.0 Prophylactic surgery for risk-factors related to malignant neoplasms
0.798 0.202 0.000
I38 Endocarditis, valve unspecified
0.796 0.204 0.000
S30.8 Other superficial injuries of abdomen, lower back and pelvis
0.796 0.204 0.000
T51.9 Alcohol, unspecified
0.795 0.205 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.794 0.206 0.000
Z95.8 Presence of other cardiac and vascular implants and grafts
0.794 0.206 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.793 0.207 0.000
S72.00 Fracture of neck of femur (closed)
0.792 0.208 0.000
M40-M43 Deforming dorsopathies
0.791 0.209 0.000
I69 Sequelae of cerebrovascular disease
0.791 0.209 0.000
N48.1 Balanoposthitis
0.790 0.210 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.789 0.211 0.000
H90 Conductive and sensorineural hearing loss
0.787 0.213 0.000
Z48 Other surgical follow-up care
0.785 0.215 0.000
Chapter X Diseases of the respiratory system
0.784 0.216 0.000
I73 Other peripheral vascular diseases
0.781 0.219 0.000
S70 Superficial injury of hip and thigh
0.781 0.219 0.000
Z95.5 Presence of coronary angioplasty implant and graft
0.781 0.219 0.000
G90-G99 Other disorders of the nervous system
0.777 0.223 0.000
I25 Chronic ischaemic heart disease
0.776 0.224 0.000
I51.8 Other ill-defined heart diseases
0.775 0.225 0.000
F43 Reaction to severe stress, and adjustment disorders
0.775 0.225 0.000
M45-M49 Spondylopathies
0.774 0.226 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.771 0.229 0.000
Z50.2 Alcohol rehabilitation
0.770 0.229 0.000
W20-W49 Exposure to inanimate mechanical forces
0.770 0.230 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.769 0.231 0.000
M20-M25 Other joint disorders
0.769 0.231 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.769 0.231 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.769 0.231 0.000
Z12.1 Special screening examination for neoplasm of intestinal tract
0.767 0.233 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.766 0.234 0.000
S20-S29 Injuries to the thorax
0.764 0.236 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.764 0.236 0.000
I36 Nonrheumatic tricuspid valve disorders
0.763 0.237 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.763 0.237 0.000
C64-C68 Malignant neoplasms of urinary tract
0.761 0.239 0.000
T78 Adverse effects, not elsewhere classified
0.761 0.239 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.759 0.241 0.000
M91-M94 Chondropathies
0.758 0.242 0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.758 0.242 0.000
Z43.6 Attention to other artificial openings of urinary tract
0.758 0.242 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.758 0.242 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.757 0.243 0.000
T79-T79 Certain early complications of trauma
0.755 0.245 0.000
Z08.9 Follow-up examination after unspecified treatment for malignant neoplasm
0.755 0.245 0.000
I77.1 Stricture of artery
0.755 0.245 0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip
0.754 0.246 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.754 0.246 0.000
I65.2 Occlusion and stenosis of carotid artery
0.752 0.248 0.000
I11 Hypertensive heart disease
0.752 0.248 0.000
N30-N39 Other diseases of urinary system
0.751 0.249 0.000
F41.1 Generalised anxiety disorder
0.750 0.249 0.000
Z54 Convalescence
0.749 0.251 0.000
S32 Fracture of lumbar spine and pelvis
0.749 0.251 0.000
H55-H59 Other disorders of eye and adnexa
0.747 0.253 0.000
F60-F69 Disorders of adult personality and behaviour
0.747 0.253 0.000
M13 Other arthritis
0.746 0.254 0.000
N45 Orchitis and epididymitis
0.745 0.255 0.000
Z50.1 Other physical therapy
0.744 0.256 0.000
I44 Atrioventricular and left bundle-branch block
0.743 0.257 0.000
H90.3 Sensorineural hearing loss, bilateral
0.743 0.257 0.000
S92.3 Fracture of metatarsal bone
0.739 0.261 0.000
N11 Chronic tubulo-interstitial nephritis
0.739 0.261 0.000
H65-H75 Diseases of middle ear and mastoid
0.738 0.262 0.000
I72.3 Aneurysm of iliac artery
0.738 0.262 0.000
S72.1 Pertrochanteric fracture
0.737 0.263 0.000
N02.9 Unspecified
0.736 0.264 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.736 0.264 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.733 0.267 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.733 0.267 0.000
I60.9 Subarachnoid haemorrhage, unspecified
0.733 0.267 0.000
F20 Schizophrenia
0.732 0.268 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.732 0.268 0.000
M65-M68 Disorders of synovium and tendon
0.731 0.269 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.731 0.269 0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction
0.731 0.269 0.000
V80-V89 Other land transport accidents
0.731 0.269 0.000
H26 Other cataract
0.731 0.269 0.000
I45.6 Preexcitation syndrome
0.730 0.270 0.000
S92.0 Fracture of calcaneus
0.729 0.271 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.728 0.272 0.000
H91 Other hearing loss
0.728 0.272 0.000
F45 Somatoform disorders
0.728 0.272 0.000
V20-V29 Motorcycle rider injured in transport accident
0.726 0.274 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.726 0.274 0.000
S60-S69 Injuries to the wrist and hand
0.725 0.274 0.000
N99.8 Other postprocedural disorders of genito-urinary system
0.725 0.275 0.000
N48.0 Leukoplakia of penis
0.724 0.276 0.000
M60-M63 Disorders of muscles
0.724 0.276 0.000
N13.5 Kinking and stricture of ureter without hydronephrosis
0.724 0.276 0.000
I47.2 Ventricular tachycardia
0.723 0.277 0.000
N36 Other disorders of urethra
0.723 0.277 0.000
J30-J39 Other diseases of upper respiratory tract
0.723 0.277 0.000
Z50.4 Psychotherapy, not elsewhere classified
0.723 0.277 0.000
F30 Manic episode
0.722 0.278 0.000
S76.4 Injury of other and unspecified muscles and tendons at thigh level
0.721 0.279 0.000
C67 Malignant neoplasm of bladder
0.721 0.279 0.000
H25 Senile cataract
0.720 0.280 0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis
0.719 0.280 0.000
M84 Disorders of continuity of bone
0.719 0.281 0.000
M81 Osteoporosis without pathological fracture
0.718 0.282 0.000
I70 Atherosclerosis
0.717 0.283 0.000
I31 Other diseases of pericardium
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
N22 Calculus of urinary tract in diseases classified elsewhere
0.716 0.284 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.716 0.284 0.000
V10-V19 Pedal cyclist injured in transport accident
0.715 0.285 0.000
N17-N19 Renal failure
0.715 0.285 0.000
S82 Fracture of lower leg, including ankle
0.715 0.285 0.000
T42.4 Benzodiazepines
0.715 0.285 0.000
R26.8 Other and unspecified abnormalities of gait and mobility
0.715 0.285 0.000
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.714 0.286 0.000
N51 Disorders of male genital organs in diseases classified elsewhere
0.714 0.286 0.000
N46 Male infertility
0.714 0.286 0.000
N44 Torsion of testis
0.714 0.286 0.000
F42 Obsessive-compulsive disorder
0.713 0.287 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.713 0.287 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.713 0.287 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.713 0.287 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.713 0.287 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.713 0.287 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.713 0.287 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.713 0.287 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.713 0.287 0.000
T36 Poisoning by systemic antibiotics
0.713 0.287 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.712 0.287 0.000
F70-F79 Mental retardation
0.712 0.287 0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified
0.712 0.288 0.000
Z02.8 Other examinations for administrative purposes
0.711 0.289 0.000
N47 Redundant prepuce, phimosis and paraphimosis
0.710 0.290 0.000
N13.8 Other obstructive and reflux uropathy
0.709 0.291 0.000
S56 Injury of muscle and tendon at forearm level
0.709 0.291 0.000
V40-V49 Car occupant injured in transport accident
0.709 0.291 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.708 0.292 0.000
Z50.0 Cardiac rehabilitation
0.708 0.292 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.708 0.292 0.000
F80-F89 Disorders of psychological development
0.708 0.292 0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction
0.708 0.292 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.708 0.292 0.000
N13.6 Pyonephrosis
0.707 0.293 0.000
T92 Sequelae of injuries of upper limb
0.707 0.293 0.000
S90 Superficial injury of ankle and foot
0.706 0.294 0.000
N42.3 Dysplasia of prostate
0.706 0.294 0.000
N42.0 Calculus of prostate
0.706 0.294 0.000
I77.6 Arteritis, unspecified
0.706 0.294 0.000
I35 Nonrheumatic aortic valve disorders
0.705 0.295 0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.704 0.296 0.000
F48 Other neurotic disorders
0.703 0.297 0.000
F44 Dissociative [conversion] disorders
0.703 0.297 0.000
X20-X29 Contact with venomous animals and plants
0.703 0.297 0.000
J09-J18 Influenza and pneumonia
0.702 0.298 0.000
M41 Scoliosis
0.702 0.298 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.702 0.298 0.000
I52 Other heart disorders in diseases classified elsewhere
0.702 0.298 0.000
I48 Atrial fibrillation and flutter
0.702 0.298 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.702 0.298 0.000
I41 Myocarditis in diseases classified elsewhere
0.702 0.298 0.000
I40 Acute myocarditis
0.702 0.298 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.702 0.298 0.000
I37 Pulmonary valve disorders
0.702 0.298 0.000
I32 Pericarditis in diseases classified elsewhere
0.702 0.298 0.000
I30 Acute pericarditis
0.702 0.298 0.000
H43-H45 Disorders of vitreous body and globe
0.702 0.298 0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.702 0.298 0.000
S72.4 Fracture of lower end of femur
0.701 0.299 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.701 0.299 0.000
I60.3 Subarachnoid haemorrhage from posterior communicating artery
0.701 0.299 0.000
N48.4 Impotence of organic origin
0.701 0.299 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.700 0.300 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.699 0.301 0.000
G70-G73 Diseases of myoneural junction and muscle
0.699 0.301 0.000
S78 Traumatic amputation of hip and thigh
0.698 0.301 0.000
S77 Crushing injury of hip and thigh
0.698 0.301 0.000
S75 Injury of blood vessels at hip and thigh level
0.698 0.301 0.000
S74 Injury of nerves at hip and thigh level
0.698 0.301 0.000
S71 Open wound of hip and thigh
0.698 0.301 0.000
Z46 Fitting and adjustment of other devices
0.698 0.302 0.000
G04 Encephalitis, myelitis and encephalomyelitis
0.697 0.302 0.000
I25.2 Old myocardial infarction
0.697 0.303 0.000
I72.4 Aneurysm of artery of lower extremity
0.697 0.303 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.696 0.304 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.696 0.304 0.000
N20.9 Urinary calculus, unspecified
0.695 0.304 0.000
I77.8 Other specified disorders of arteries and arterioles
0.695 0.305 0.000
M00-M03 Infectious arthropathies
0.695 0.305 0.000
F41.8 Other specified anxiety disorders
0.693 0.306 0.000
F41.3 Other mixed anxiety disorders
0.693 0.306 0.000
N05 Unspecified nephritic syndrome
0.692 0.307 0.000
S50 Superficial injury of forearm
0.692 0.308 0.000
F33.9 Recurrent depressive disorder, unspecified
0.692 0.308 0.000
I62 Other nontraumatic intracranial haemorrhage
0.691 0.308 0.000
M13.9 Arthritis, unspecified
0.691 0.309 0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.690 0.310 0.000
X60-X84 Intentional self-harm
0.690 0.310 0.000
S52 Fracture of forearm
0.690 0.310 0.000
C67.9 Bladder, unspecified
0.689 0.311 0.000
Z44 Fitting and adjustment of external prosthetic device
0.689 0.311 0.000
S72.2 Subtrochanteric fracture
0.689 0.311 0.000
I46.0 Cardiac arrest with successful resuscitation
0.688 0.312 0.000
S81 Open wound of lower leg
0.688 0.312 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.688 0.312 0.000
Z50.6 Orthoptic training
0.687 0.313 0.000
Z50.3 Drug rehabilitation
0.687 0.313 0.000
C50-C50 Malignant neoplasm of breast
0.685 0.315 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.685 0.315 0.000
T43.9 Psychotropic drug, unspecified
0.685 0.315 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.685 0.315 0.000
T43.6 Psychostimulants with abuse potential
0.685 0.315 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.685 0.315 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.685 0.315 0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere
0.684 0.316 0.000
N15 Other renal tubulo-interstitial diseases
0.684 0.316 0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
0.684 0.316 0.000
N10 Acute tubulo-interstitial nephritis
0.684 0.316 0.000
F32.1 Moderate depressive episode
0.683 0.317 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.683 0.317 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.683 0.317 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.683 0.317 0.000
R30-R39 Symptoms and signs involving the urinary system
0.682 0.318 0.000
F40 Phobic anxiety disorders
0.682 0.318 0.000
N41.0 Acute prostatitis
0.681 0.319 0.000
J33 Nasal polyp
0.680 0.320 0.000
F38 Other mood [affective] disorders
0.680 0.320 0.000
F34 Persistent mood [affective] disorders
0.680 0.320 0.000
F39 Unspecified mood [affective] disorder
0.680 0.320 0.000
M82 Osteoporosis in diseases classified elsewhere
0.679 0.321 0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.679 0.321 0.000
N36.8 Other specified disorders of urethra
0.679 0.321 0.000
I74 Arterial embolism and thrombosis
0.678 0.322 0.000
Z95.4 Presence of other heart-valve replacement
0.678 0.322 0.000
I11.9 Hypertensive heart disease without (congestive) heart failure
0.677 0.323 0.000
S19 Other and unspecified injuries of neck
0.676 0.324 0.000
N99.0 Postprocedural renal failure
0.675 0.325 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.675 0.325 0.000
R33 Retention of urine
0.674 0.326 0.000
M87 Osteonecrosis
0.673 0.326 0.000
I49 Other cardiac arrhythmias
0.673 0.327 0.000
Z08.7 Follow-up examination after combined treatment for malignant neoplasm
0.672 0.328 0.000
M70-M79 Other soft tissue disorders
0.672 0.328 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.672 0.328 0.000
S40-S49 Injuries to the shoulder and upper arm
0.671 0.329 0.000
I27 Other pulmonary heart diseases
0.671 0.329 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.671 0.329 0.000
T65 Toxic effect of other and unspecified substances
0.671 0.329 0.000
T63 Toxic effect of contact with venomous animals
0.671 0.329 0.000
T62 Toxic effect of other noxious substances eaten as food
0.671 0.329 0.000
T61 Toxic effect of noxious substances eaten as seafood
0.671 0.329 0.000
T60 Toxic effect of pesticides
0.671 0.329 0.000
T59 Toxic effect of other gases, fumes and vapours
0.671 0.329 0.000
T57 Toxic effect of other inorganic substances
0.671 0.329 0.000
T56 Toxic effect of metals
0.671 0.329 0.000
T54 Toxic effect of corrosive substances
0.671 0.329 0.000
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone
0.671 0.329 0.000
T52 Toxic effect of organic solvents
0.671 0.329 0.000
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants
0.671 0.329 0.000
T58 Toxic effect of carbon monoxide
0.671 0.329 0.000
T55 Toxic effect of soaps and detergents
0.671 0.329 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.670 0.330 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.670 0.330 0.000
I25.3 Aneurysm of heart
0.669 0.331 0.000
I45.8 Other specified conduction disorders
0.669 0.331 0.000
I45.5 Other specified heart block
0.669 0.331 0.000
I45.4 Nonspecific intraventricular block
0.669 0.331 0.000
I45.3 Trifascicular block
0.669 0.331 0.000
I45.2 Bifascicular block
0.669 0.331 0.000
I45.0 Right fascicular block
0.669 0.331 0.000
H26.4 After-cataract
0.668 0.332 0.000
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.668 0.332 0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.668 0.332 0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.668 0.332 0.000
Z95.0 Presence of cardiac pacemaker
0.668 0.332 0.000
F41.2 Mixed anxiety and depressive disorder
0.668 0.332 0.000
Z08.8 Follow-up examination after other treatment for malignant neoplasm
0.667 0.332 0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression
0.667 0.333 0.000
G23 Other degenerative diseases of basal ganglia
0.666 0.334 0.000
G21 Secondary Parkinsonism
0.666 0.334 0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere
0.666 0.334 0.000
G22 Parkinsonism in diseases classified elsewhere
0.666 0.334 0.000
S92.30 Fracture of metatarsal bone (closed)
0.665 0.335 0.000
N13.7 Vesicoureteral-reflux-associated uropathy
0.665 0.335 0.000
N04 Nephrotic syndrome
0.665 0.335 0.000
F29 Unspecified nonorganic psychosis
0.665 0.335 0.000
G25.0 Essential tremor
0.664 0.336 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.663 0.336 0.000
M80 Osteoporosis with pathological fracture
0.663 0.336 0.000
N41.8 Other inflammatory diseases of prostate
0.663 0.337 0.000
N41.3 Prostatocystitis
0.663 0.337 0.000
N41.2 Abscess of prostate
0.663 0.337 0.000
Y35-Y36 Legal intervention and operations of war
0.663 0.337 0.000
Y10-Y34 Event of undetermined intent
0.663 0.337 0.000
Y00-Y09 Assault
0.663 0.337 0.000
X85-X99 Assault
0.663 0.337 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.663 0.337 0.000
X50-X57 Overexertion, travel and privation
0.663 0.337 0.000
X30-X39 Exposure to forces of nature
0.663 0.337 0.000
X10-X19 Contact with heat and hot substances
0.663 0.337 0.000
X00-X09 Exposure to smoke, fire and flames
0.663 0.337 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.663 0.337 0.000
W75-W84 Other accidental threats to breathing
0.663 0.337 0.000
W65-W74 Accidental drowning and submersion
0.663 0.337 0.000
W50-W64 Exposure to animate mechanical forces
0.663 0.337 0.000
V98-V99 Other and unspecified transport accidents
0.663 0.337 0.000
V95-V97 Air and space transport accidents
0.663 0.337 0.000
V90-V94 Water transport accidents
0.663 0.337 0.000
V70-V79 Bus occupant injured in transport accident
0.663 0.337 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.663 0.337 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.663 0.337 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.663 0.337 0.000
V01-V09 Pedestrian injured in transport accident
0.663 0.337 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.663 0.337 0.000
Z10 Routine general health check-up of defined subpopulation
0.662 0.338 0.000
N48.9 Disorder of penis, unspecified
0.662 0.338 0.000
N48.5 Ulcer of penis
0.662 0.338 0.000
N48.3 Priapism
0.662 0.338 0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis
0.662 0.338 0.000
S37 Injury of urinary and pelvic organs
0.662 0.338 0.000
S36 Injury of intra-abdominal organs
0.662 0.338 0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level
0.662 0.338 0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level
0.662 0.338 0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis
0.662 0.338 0.000
S31 Open wound of abdomen, lower back and pelvis
0.662 0.338 0.000
S79 Other and unspecified injuries of hip and thigh
0.662 0.338 0.000
W29 Contact with other powered hand tools and household machinery
0.662 0.338 0.000
I72.8 Aneurysm of other specified arteries
0.661 0.339 0.000
R27 Other lack of coordination
0.661 0.339 0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.659 0.340 0.000
T42.5 Mixed antiepileptics, not elsewhere classified
0.659 0.340 0.000
T42.3 Barbiturates
0.659 0.340 0.000
T42.2 Succinimides and oxazolidinediones
0.659 0.340 0.000
T42.1 Iminostilbenes
0.659 0.340 0.000
T42.0 Hydantoin derivatives
0.659 0.340 0.000
S72.9 Fracture of femur, part unspecified
0.659 0.341 0.000
S72.8 Fractures of other parts of femur
0.659 0.341 0.000
S72.7 Multiple fractures of femur
0.659 0.341 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.659 0.341 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.659 0.341 0.000
I33 Acute and subacute endocarditis
0.659 0.341 0.000
D69 Purpura and other haemorrhagic conditions
0.659 0.341 0.000
S72.3 Fracture of shaft of femur
0.658 0.342 0.000
H80-H83 Diseases of inner ear
0.658 0.342 0.000
Z48.8 Other specified surgical follow-up care
0.658 0.342 0.000
G06 Intracranial and intraspinal abscess and granuloma
0.657 0.343 0.000
I44.3 Other and unspecified atrioventricular block
0.657 0.343 0.000
F32.9 Depressive episode, unspecified
0.657 0.343 0.000
Z95.2 Presence of prosthetic heart valve
0.655 0.345 0.000
Z08.1 Follow-up examination after radiotherapy for malignant neoplasm
0.655 0.345 0.000
N30 Cystitis
0.655 0.345 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.654 0.346 0.000
N13.9 Obstructive and reflux uropathy, unspecified
0.653 0.347 0.000
N48.2 Other inflammatory disorders of penis
0.653 0.347 0.000
G30-G32 Other degenerative diseases of the nervous system
0.652 0.347 0.000
I10 Essential (primary) hypertension
0.652 0.348 0.000
S99 Other and unspecified injuries of ankle and foot
0.652 0.348 0.000
S98 Traumatic amputation of ankle and foot
0.652 0.348 0.000
S97 Crushing injury of ankle and foot
0.652 0.348 0.000
S96 Injury of muscle and tendon at ankle and foot level
0.652 0.348 0.000
S95 Injury of blood vessels at ankle and foot level
0.652 0.348 0.000
S94 Injury of nerves at ankle and foot level
0.652 0.348 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.652 0.348 0.000
M89 Other disorders of bone
0.651 0.349 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.650 0.350 0.000
G24 Dystonia
0.650 0.350 0.000
S10 Superficial injury of neck
0.650 0.350 0.000
Z08.2 Follow-up examination after chemotherapy for malignant neoplasm
0.650 0.350 0.000
E50-E64 Other nutritional deficiencies
0.650 0.350 0.000
Z49 Care involving dialysis
0.650 0.350 0.000
F32.0 Mild depressive episode
0.650 0.350 0.000
I25.5 Ischaemic cardiomyopathy
0.649 0.351 0.000
M22 Disorders of patella
0.649 0.351 0.000
I77.5 Necrosis of artery
0.649 0.351 0.000
I77.4 Coeliac artery compression syndrome
0.649 0.351 0.000
I77.3 Arterial fibromuscular dysplasia
0.649 0.351 0.000
I77.2 Rupture of artery
0.649 0.351 0.000
I77.0 Arteriovenous fistula, acquired
0.649 0.351 0.000
H47 Other disorders of optic [2nd] nerve and visual pathways
0.649 0.351 0.000
I05-I09 Chronic rheumatic heart diseases
0.649 0.351 0.000
N50 Other disorders of male genital organs
0.649 0.351 0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level
0.648 0.352 0.000
I61 Intracerebral haemorrhage
0.648 0.352 0.000
Z73 Problems related to life-management difficulty
0.648 0.352 0.000
S92.00 Fracture of calcaneus (closed)
0.648 0.352 0.000
Z12.8 Special screening examination for neoplasm of other sites
0.645 0.355 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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