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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs116965022
log Bayes Factor = 11.9178
Chromosome 17   position 15,764,366  (GRCh37) Explore rs116965022 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter VII Diseases of the eye and adnexa
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.997 0.003 0.000
M20-M25 Other joint disorders
0.995 0.005 0.000
E65-E68 Obesity and other hyperalimentation
0.995 0.005 0.000
E66 Obesity
0.993 0.007 0.000
E66.9 Obesity, unspecified
0.992 0.008 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.986 0.014 0.000
Chapter I Certain infectious and parasitic diseases
0.982 0.018 0.000
S00-S09 Injuries to the head
0.980 0.020 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.974 0.026 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.970 0.030 0.000
M45-M49 Spondylopathies
0.969 0.031 0.000
Chapter IX Diseases of the circulatory system
0.966 0.034 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.961 0.039 0.000
H52 Disorders of refraction and accommodation
0.957 0.043 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.953 0.047 0.000
H55-H59 Other disorders of eye and adnexa
0.953 0.047 0.000
M20 Acquired deformities of fingers and toes
0.944 0.056 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.939 0.061 0.000
M48 Other spondylopathies
0.939 0.061 0.000
Chapter XI Diseases of the digestive system
0.936 0.064 0.000
S01 Open wound of head
0.935 0.065 0.000
S80-S89 Injuries to the knee and lower leg
0.932 0.068 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.930 0.070 0.000
Chapter VI Diseases of the nervous system
0.929 0.071 0.000
B35-B49 Mycoses
0.925 0.075 0.000
I74 Arterial embolism and thrombosis
0.924 0.076 0.000
I80 Phlebitis and thrombophlebitis
0.924 0.076 0.000
S50-S59 Injuries to the elbow and forearm
0.922 0.078 0.000
K70-K77 Diseases of liver
0.920 0.080 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.912 0.088 0.000
M48.0 Spinal stenosis
0.911 0.089 0.000
M20.4 Other hammer toe(s) (acquired)
0.907 0.093 0.000
M22 Disorders of patella
0.905 0.095 0.000
H25-H28 Disorders of lens
0.903 0.097 0.000
H52.1 Myopia
0.900 0.100 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.899 0.101 0.000
T84.0 Mechanical complication of internal joint prosthesis
0.893 0.107 0.000
M25 Other joint disorders, not elsewhere classified
0.891 0.109 0.000
K11 Diseases of salivary glands
0.890 0.110 0.000
S40-S49 Injuries to the shoulder and upper arm
0.888 0.112 0.000
H04 Disorders of lachrymal system
0.886 0.114 0.000
S60-S69 Injuries to the wrist and hand
0.884 0.116 0.000
M23 Internal derangement of knee
0.879 0.121 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.877 0.123 0.000
M86-M90 Other osteopathies
0.873 0.127 0.000
K70 Alcoholic liver disease
0.869 0.131 0.000
A00-A09 Intestinal infectious diseases
0.869 0.131 0.000
K20-K31 Diseases of oesophagus, stomach and duodenum
0.869 0.131 0.000
M70-M79 Other soft tissue disorders
0.865 0.135 0.000
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities
0.863 0.137 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.863 0.137 0.000
B95-B98 Bacterial, viral and other infectious agents
0.862 0.138 0.000
S82 Fracture of lower leg, including ankle
0.862 0.138 0.000
B37 Candidiasis
0.860 0.140 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.859 0.141 0.000
K29 Gastritis and duodenitis
0.858 0.142 0.000
H01 Other inflammation of eyelid
0.858 0.142 0.000
I77 Other disorders of arteries and arterioles
0.857 0.143 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.854 0.146 0.000
H26 Other cataract
0.852 0.148 0.000
M20.5 Other deformities of toe(s) (acquired)
0.850 0.150 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.849 0.151 0.000
E10-E14 Diabetes mellitus
0.847 0.153 0.000
H55 Nystagmus and other irregular eye movements
0.845 0.155 0.000
K29.5 Chronic gastritis, unspecified
0.845 0.155 0.000
H52.2 Astigmatism
0.843 0.157 0.000
K11.2 Sialoadenitis
0.840 0.160 0.000
I74.5 Embolism and thrombosis of iliac artery
0.838 0.162 0.000
K72 Hepatic failure, not elsewhere classified
0.838 0.162 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.837 0.163 0.000
T84.1 Mechanical complication of internal fixation device of bones of limb
0.832 0.168 0.000
H26.8 Other specified cataract
0.831 0.169 0.000
M45 Ankylosing spondylitis
0.829 0.171 0.000
S82.3 Fracture of lower end of tibia
0.829 0.171 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.828 0.172 0.000
K70.9 Alcoholic liver disease, unspecified
0.826 0.174 0.000
H04.2 Epiphora
0.824 0.176 0.000
M48.06 Spinal stenosis (Lumbar region)
0.822 0.178 0.000
H02 Other disorders of eyelid
0.818 0.182 0.000
H57 Other disorders of eye and adnexa
0.817 0.183 0.000
M48.07 Spinal stenosis (Lumbosacral region)
0.817 0.183 0.000
G70-G73 Diseases of myoneural junction and muscle
0.815 0.185 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.815 0.185 0.000
S52 Fracture of forearm
0.814 0.186 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.813 0.187 0.000
S02 Fracture of skull and facial bones
0.813 0.187 0.000
Chapter XX External causes of morbidity and mortality
0.812 0.188 0.000
E70-E90 Metabolic disorders
0.809 0.191 0.000
K29.8 Duodenitis
0.807 0.193 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.807 0.193 0.000
B37.8 Candidiasis of other sites
0.806 0.194 0.000
S82.30 Fracture of lower end of tibia (closed)
0.806 0.194 0.000
K29.1 Other acute gastritis
0.806 0.194 0.000
H10-H13 Disorders of conjunctiva
0.805 0.194 0.000
S01.9 Open wound of head, part unspecified
0.805 0.195 0.000
M50-M54 Other dorsopathies
0.803 0.197 0.000
I89.0 Lymphoedema, not elsewhere classified
0.802 0.198 0.000
S05 Injury of eye and orbit
0.801 0.199 0.000
H53-H54 Visual disturbances and blindness
0.800 0.200 0.000
H49 Paralytic strabismus
0.799 0.201 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.799 0.201 0.000
M34 Systemic sclerosis
0.798 0.202 0.000
H05 Disorders of orbit
0.796 0.204 0.000
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities
0.796 0.204 0.000
I80.1 Phlebitis and thrombophlebitis of femoral vein
0.795 0.205 0.000
S01.4 Open wound of cheek and temporomandibular area
0.791 0.209 0.000
M24 Other specific joint derangements
0.790 0.210 0.000
M23.8 Other internal derangements of knee
0.790 0.210 0.000
K25 Gastric ulcer
0.790 0.210 0.000
M20.0 Deformity of finger(s)
0.789 0.211 0.000
I73 Other peripheral vascular diseases
0.788 0.212 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.786 0.214 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.785 0.215 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.784 0.215 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.784 0.216 0.000
S00 Superficial injury of head
0.784 0.216 0.000
M23.3 Other meniscus derangements
0.782 0.218 0.000
I86 Varicose veins of other sites
0.778 0.222 0.000
B50-B64 Protozoal diseases
0.777 0.223 0.000
H01.0 Blepharitis
0.777 0.223 0.000
S01.2 Open wound of nose
0.775 0.225 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.774 0.226 0.000
S01.7 Multiple open wounds of head
0.774 0.226 0.000
S51 Open wound of forearm
0.773 0.227 0.000
M54 Dorsalgia
0.773 0.227 0.000
T82.1 Mechanical complication of cardiac electronic device
0.771 0.229 0.000
Chapter XXII Codes for special purposes
0.770 0.230 0.000
S81 Open wound of lower leg
0.769 0.231 0.000
T92 Sequelae of injuries of upper limb
0.769 0.231 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.769 0.231 0.000
S06 Intracranial injury
0.768 0.232 0.000
G30-G32 Other degenerative diseases of the nervous system
0.767 0.233 0.000
M89 Other disorders of bone
0.766 0.234 0.000
H52.0 Hypermetropia
0.764 0.236 0.000
H52.3 Anisometropia and aniseikonia
0.764 0.236 0.000
K12 Stomatitis and related lesions
0.764 0.236 0.000
K31 Other diseases of stomach and duodenum
0.764 0.236 0.000
G90-G99 Other disorders of the nervous system
0.763 0.237 0.000
G35 Multiple sclerosis
0.762 0.238 0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft
0.762 0.238 0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts
0.759 0.241 0.000
M25.7 Osteophyte
0.758 0.242 0.000
S52.5 Fracture of lower end of radius
0.758 0.242 0.000
S10-S19 Injuries to the neck
0.756 0.244 0.000
A09 Diarrhoea and gastro-enteritis of presumed infectious origin
0.756 0.244 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.754 0.246 0.000
I87 Other disorders of veins
0.753 0.247 0.000
K11.6 Mucocele of salivary gland
0.753 0.247 0.000
T87 Complications peculiar to reattachment and amputation
0.753 0.247 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.752 0.248 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.752 0.248 0.000
S62 Fracture at wrist and hand level
0.752 0.248 0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts
0.750 0.250 0.000
T81 Complications of procedures, not elsewhere classified
0.747 0.253 0.000
S89 Other and unspecified injuries of lower leg
0.747 0.253 0.000
M72 Fibroblastic disorders
0.746 0.253 0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts
0.746 0.254 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.745 0.255 0.000
M23.9 Internal derangement of knee, unspecified
0.745 0.255 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.744 0.256 0.000
T79-T79 Certain early complications of trauma
0.741 0.259 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.740 0.259 0.000
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified
0.740 0.260 0.000
M22.4 Chondromalacia patellae
0.740 0.260 0.000
K01 Embedded and impacted teeth
0.739 0.261 0.000
I73.9 Peripheral vascular disease, unspecified
0.738 0.262 0.000
M48.00 Spinal stenosis (Multiple sites in spine)
0.738 0.262 0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.738 0.262 0.000
H58 Other disorders of eye and adnexa in diseases classified elsewhere
0.738 0.262 0.000
B65-B83 Helminthiases
0.737 0.263 0.000
M46 Other inflammatory spondylopathies
0.737 0.263 0.000
M48.09 Spinal stenosis (Site unspecified)
0.737 0.263 0.000
B15-B19 Viral hepatitis
0.736 0.264 0.000
K26 Duodenal ulcer
0.735 0.265 0.000
S42 Fracture of shoulder and upper arm
0.735 0.265 0.000
B49 Unspecified mycosis
0.733 0.267 0.000
B44 Aspergillosis
0.732 0.268 0.000
M22.3 Other derangements of patella
0.732 0.268 0.000
H57.9 Disorder of eye and adnexa, unspecified
0.732 0.268 0.000
B37.0 Candidal stomatitis
0.732 0.268 0.000
Chapter X Diseases of the respiratory system
0.732 0.268 0.000
H02.1 Ectropion of eyelid
0.731 0.269 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.730 0.270 0.000
Q60-Q64 Congenital malformations of the urinary system
0.730 0.270 0.000
I72 Other aneurysm
0.730 0.270 0.000
T81.4 Infection following a procedure, not elsewhere classified
0.730 0.270 0.000
A80-A89 Viral infections of the central nervous system
0.728 0.272 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.727 0.273 0.000
M48.5 Collapsed vertebra, not elsewhere classified
0.727 0.273 0.000
G70 Myasthenia gravis and other myoneural disorders
0.727 0.273 0.000
M54.1 Radiculopathy
0.726 0.273 0.000
K72.9 Hepatic failure, unspecified
0.726 0.274 0.000
S01.0 Open wound of scalp
0.726 0.274 0.000
S82.1 Fracture of upper end of tibia
0.726 0.274 0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters
0.724 0.276 0.000
K09 Cysts of oral region, not elsewhere classified
0.724 0.276 0.000
H02.5 Other disorders affecting eyelid function
0.720 0.280 0.000
I80.9 Phlebitis and thrombophlebitis of unspecified site
0.718 0.282 0.000
S40 Superficial injury of shoulder and upper arm
0.718 0.282 0.000
S52.50 Fracture of lower end of radius (closed)
0.717 0.283 0.000
H20 Iridocyclitis
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
E20-E35 Disorders of other endocrine glands
0.717 0.283 0.000
M22.2 Patellofemoral disorders
0.717 0.283 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.717 0.283 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.717 0.283 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.716 0.284 0.000
T86 Failure and rejection of transplanted organs and tissues
0.714 0.286 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.713 0.286 0.000
S63.4 Traumatic rupture of ligament of finger at metacarpophalangeal and interphalangeal joint(s)
0.714 0.286 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.713 0.286 0.000
M33 Dermatopolymyositis
0.713 0.286 0.000
M32 Systemic lupus erythematosus
0.713 0.286 0.000
M30 Polyarteritis nodosa and related conditions
0.713 0.286 0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]
0.713 0.286 0.000
K72.0 Acute and subacute hepatic failure
0.713 0.287 0.000
E67 Other hyperalimentation
0.713 0.287 0.000
E68 Sequelae of hyperalimentation
0.713 0.287 0.000
E65 Localised adiposity
0.713 0.287 0.000
S90-S99 Injuries to the ankle and foot
0.713 0.287 0.000
G37 Other demyelinating diseases of central nervous system
0.713 0.287 0.000
M00-M03 Infectious arthropathies
0.712 0.288 0.000
M65-M68 Disorders of synovium and tendon
0.712 0.288 0.000
E66.2 Extreme obesity with alveolar hypoventilation
0.712 0.288 0.000
E66.1 Drug-induced obesity
0.712 0.288 0.000
E66.0 Obesity due to excess calories
0.712 0.288 0.000
T82.0 Mechanical complication of heart valve prosthesis
0.711 0.288 0.000
K73 Chronic hepatitis, not elsewhere classified
0.711 0.289 0.000
M79.6 Pain in limb
0.711 0.289 0.000
K06 Other disorders of gingiva and edentulous alveolar ridge
0.710 0.290 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.710 0.290 0.000
M80-M85 Disorders of bone density and structure
0.709 0.291 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.709 0.291 0.000
K25.4 Chronic or unspecified with haemorrhage
0.708 0.292 0.000
I05-I09 Chronic rheumatic heart diseases
0.707 0.293 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.705 0.295 0.000
M22.8 Other disorders of patella
0.705 0.295 0.000
E14 Unspecified diabetes mellitus
0.705 0.295 0.000
M79.1 Myalgia
0.705 0.295 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.705 0.295 0.000
B99-B99 Other infectious diseases
0.704 0.296 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.704 0.296 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.704 0.296 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.704 0.296 0.000
A75-A79 Rickettsioses
0.704 0.296 0.000
A70-A74 Other diseases caused by chlamydiae
0.704 0.296 0.000
A65-A69 Other spirochaetal diseases
0.704 0.296 0.000
A20-A28 Certain zoonotic bacterial diseases
0.704 0.296 0.000
A15-A19 Tuberculosis
0.704 0.296 0.000
I85 Oesophageal varices
0.704 0.296 0.000
K11.8 Other diseases of salivary glands
0.703 0.297 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.702 0.297 0.000
A09.9 Gastroenteritis and colitis of unspecified origin
0.703 0.297 0.000
S08 Traumatic amputation of part of head
0.702 0.297 0.000
S07 Crushing injury of head
0.702 0.297 0.000
S04 Injury of cranial nerves
0.702 0.297 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.702 0.297 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.702 0.298 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.702 0.298 0.000
K76 Other diseases of liver
0.701 0.299 0.000
H51 Other disorders of binocular movement
0.699 0.301 0.000
M91-M94 Chondropathies
0.698 0.301 0.000
T84.3 Mechanical complication of other bone devices, implants and grafts
0.698 0.302 0.000
M45.X9 Ankylosing spondylitis (Site unspecified)
0.697 0.303 0.000
E00-E07 Disorders of thyroid gland
0.697 0.303 0.000
K05 Gingivitis and periodontal diseases
0.696 0.304 0.000
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level
0.696 0.304 0.000
H02.2 Lagophthalmos
0.696 0.304 0.000
H03 Disorders of eyelid in diseases classified elsewhere
0.695 0.304 0.000
M49 Spondylopathies in diseases classified elsewhere
0.695 0.305 0.000
H53 Visual disturbances
0.694 0.306 0.000
K74 Fibrosis and cirrhosis of liver
0.694 0.306 0.000
K07 Dentofacial anomalies [including malocclusion]
0.694 0.306 0.000
I70 Atherosclerosis
0.693 0.307 0.000
I00-I02 Acute rheumatic fever
0.693 0.307 0.000
B25-B34 Other viral diseases
0.693 0.307 0.000
A02 Other Salmonella infections
0.692 0.308 0.000
K02 Dental caries
0.692 0.308 0.000
E66.8 Other obesity
0.691 0.309 0.000
I77.8 Other specified disorders of arteries and arterioles
0.691 0.309 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.690 0.310 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.690 0.310 0.000
S50 Superficial injury of forearm
0.689 0.311 0.000
H21 Other disorders of iris and ciliary body
0.688 0.311 0.000
M05-M14 Inflammatory polyarthropathies
0.688 0.312 0.000
K25.9 Unspecified as acute or chronic, without haemorrhage or perforation
0.688 0.312 0.000
V20-V29 Motorcycle rider injured in transport accident
0.687 0.313 0.000
H52.7 Disorder of refraction, unspecified
0.686 0.314 0.000
H52.6 Other disorders of refraction
0.686 0.314 0.000
H52.5 Disorders of accommodation
0.686 0.314 0.000
H52.4 Presbyopia
0.686 0.314 0.000
H04.1 Other disorders of lachrymal gland
0.686 0.314 0.000
I77.0 Arteriovenous fistula, acquired
0.686 0.314 0.000
K11.1 Hypertrophy of salivary gland
0.685 0.315 0.000
T92.5 Sequelae of injury of muscle and tendon of upper limb
0.685 0.315 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.685 0.315 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.685 0.315 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.684 0.316 0.000
E40-E46 Malnutrition
0.684 0.316 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.683 0.317 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.683 0.317 0.000
H26.4 After-cataract
0.680 0.320 0.000
M25.5 Pain in joint
0.679 0.321 0.000
H04.3 Acute and unspecified inflammation of lachrymal passages
0.678 0.322 0.000
K35-K38 Diseases of appendix
0.678 0.322 0.000
H11 Other disorders of conjunctiva
0.678 0.322 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.677 0.323 0.000
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level
0.677 0.323 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.676 0.324 0.000
H16 Keratitis
0.675 0.325 0.000
H02.9 Disorder of eyelid, unspecified
0.675 0.325 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.674 0.326 0.000
I88 Nonspecific lymphadenitis
0.673 0.326 0.000
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified
0.673 0.327 0.000
M48.9 Spondylopathy, unspecified
0.673 0.327 0.000
M48.8 Other specified spondylopathies
0.673 0.327 0.000
M48.4 Fatigue fracture of vertebra
0.673 0.327 0.000
M48.3 Traumatic spondylopathy
0.673 0.327 0.000
M48.2 Kissing spine
0.673 0.327 0.000
M48.1 Ankylosing hyperostosis [Forestier]
0.673 0.327 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.673 0.327 0.000
S68 Traumatic amputation of wrist and hand
0.672 0.328 0.000
M79.65 Pain in limb (Pelvic region and thigh)
0.671 0.329 0.000
M87 Osteonecrosis
0.671 0.329 0.000
H49.1 Fourth [trochlear] nerve palsy
0.671 0.329 0.000
I80.8 Phlebitis and thrombophlebitis of other sites
0.670 0.330 0.000
H02.6 Xanthelasma of eyelid
0.670 0.330 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.669 0.330 0.000
K70.3 Alcoholic cirrhosis of liver
0.669 0.331 0.000
S88 Traumatic amputation of lower leg
0.668 0.332 0.000
S87 Crushing injury of lower leg
0.668 0.332 0.000
S86 Injury of muscle and tendon at lower leg level
0.668 0.332 0.000
S85 Injury of blood vessels at lower leg level
0.668 0.332 0.000
S84 Injury of nerves at lower leg level
0.668 0.332 0.000
M79.0 Rheumatism, unspecified
0.667 0.333 0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft
0.667 0.333 0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis
0.667 0.333 0.000
T82.4 Mechanical complication of vascular dialysis catheter
0.667 0.333 0.000
T82.3 Mechanical complication of other vascular grafts
0.667 0.333 0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts
0.667 0.333 0.000
E13 Other specified diabetes mellitus
0.666 0.334 0.000
K29.2 Alcoholic gastritis
0.665 0.335 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.665 0.335 0.000
M40-M43 Deforming dorsopathies
0.664 0.335 0.000
M31 Other necrotising vasculopathies
0.664 0.336 0.000
M23.30 Other meniscus derangements (Multiple sites)
0.664 0.336 0.000
B48 Other mycoses, not elsewhere classified
0.663 0.336 0.000
B47 Mycetoma
0.663 0.336 0.000
B46 Zygomycosis
0.663 0.336 0.000
B45 Cryptococcosis
0.663 0.336 0.000
B43 Chromomycosis and phaeomycotic abscess
0.663 0.336 0.000
B42 Sporotrichosis
0.663 0.336 0.000
B41 Paracoccidioidomycosis
0.663 0.336 0.000
B40 Blastomycosis
0.663 0.336 0.000
B39 Histoplasmosis
0.663 0.336 0.000
B38 Coccidioidomycosis
0.663 0.336 0.000
B36 Other superficial mycoses
0.663 0.336 0.000
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters
0.663 0.337 0.000
G70.0 Myasthenia gravis
0.663 0.337 0.000
I74.9 Embolism and thrombosis of unspecified artery
0.663 0.337 0.000
I74.8 Embolism and thrombosis of other arteries
0.663 0.337 0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.663 0.337 0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.663 0.337 0.000
I74.0 Embolism and thrombosis of abdominal aorta
0.663 0.337 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.663 0.337 0.000
G95 Other diseases of spinal cord
0.662 0.338 0.000
M89.9 Disorder of bone, unspecified
0.662 0.338 0.000
M23.81 Other internal derangements of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.662 0.338 0.000
S59 Other and unspecified injuries of forearm
0.661 0.339 0.000
S58 Traumatic amputation of forearm
0.661 0.339 0.000
S57 Crushing injury of forearm
0.661 0.339 0.000
S56 Injury of muscle and tendon at forearm level
0.661 0.339 0.000
S55 Injury of blood vessels at forearm level
0.661 0.339 0.000
S54 Injury of nerves at forearm level
0.661 0.339 0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow
0.661 0.339 0.000
T90 Sequelae of injuries of head
0.661 0.339 0.000
M72.0 Palmar fascial fibromatosis [Dupuytren]
0.660 0.340 0.000
K77 Liver disorders in diseases classified elsewhere
0.659 0.341 0.000
K71 Toxic liver disease
0.659 0.341 0.000
K29.0 Acute haemorrhagic gastritis
0.659 0.341 0.000
M76 Enthesopathies of lower limb, excluding foot
0.659 0.341 0.000
S05.0 Injury of conjunctiva and corneal abrasion without mention of foreign body
0.659 0.341 0.000
S20-S29 Injuries to the thorax
0.657 0.343 0.000
S01.1 Open wound of eyelid and periocular area
0.657 0.343 0.000
H18 Other disorders of cornea
0.656 0.344 0.000
K90-K93 Other diseases of the digestive system
0.656 0.344 0.000
E87.2 Acidosis
0.656 0.344 0.000
I89.8 Other specified non-infective disorders of lymphatic vessels and lymph nodes
0.656 0.344 0.000
S01.5 Open wound of lip and oral cavity
0.655 0.345 0.000
S00.0 Superficial injury of scalp
0.655 0.345 0.000
K03 Other diseases of hard tissues of teeth
0.654 0.346 0.000
M48.08 Spinal stenosis (Sacral and sacrococcygeal region)
0.653 0.346 0.000
M48.05 Spinal stenosis (Thoracolumbar region)
0.653 0.346 0.000
M48.04 Spinal stenosis (Thoracic region)
0.653 0.346 0.000
M48.03 Spinal stenosis (Cervicothoracic region)
0.653 0.346 0.000
M48.01 Spinal stenosis (Occipito-atlanto-axial region)
0.653 0.346 0.000
I10-I15 Hypertensive diseases
0.653 0.347 0.000
Q50-Q56 Congenital malformations of genital organs
0.652 0.348 0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.651 0.348 0.000
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.651 0.349 0.000
M25.76 Osteophyte (Lower leg)
0.651 0.349 0.000
S62.6 Fracture of other finger
0.651 0.349 0.000
I77.6 Arteritis, unspecified
0.650 0.350 0.000
M22.1 Recurrent subluxation of patella
0.649 0.351 0.000
M22.9 Disorder of patella, unspecified
0.649 0.351 0.000
M22.0 Recurrent dislocation of patella
0.649 0.351 0.000
K10 Other diseases of jaws
0.649 0.351 0.000
M23.99 Internal derangement of knee, unspecified (Unspecified ligament or Unspecified meniscus)
0.649 0.351 0.000
K12.2 Cellulitis and abscess of mouth
0.648 0.352 0.000
H28 Cataract and other disorders of lens in diseases classified elsewhere
0.648 0.352 0.000
Q18 Other congenital malformations of face and neck
0.647 0.353 0.000
H40-H42 Glaucoma
0.646 0.353 0.000
E88 Other metabolic disorders
0.646 0.354 0.000
I81 Portal vein thrombosis
0.646 0.354 0.000
M34.8 Other forms of systemic sclerosis
0.645 0.355 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.645 0.355 0.000
Q80-Q89 Other congenital malformations
0.645 0.355 0.000
Q35-Q37 Cleft lip and cleft palate
0.645 0.355 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.645 0.355 0.000
H27 Other disorders of lens
0.644 0.356 0.000
S82.4 Fracture of fibula alone
0.643 0.357 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.643 0.357 0.000
S67 Crushing injury of wrist and hand
0.641 0.358 0.000
E11 Non-insulin-dependent diabetes mellitus
0.640 0.360 0.000
K11.9 Disease of salivary gland, unspecified
0.640 0.360 0.000
M25.4 Effusion of joint
0.640 0.360 0.000
M23.5 Chronic instability of knee
0.639 0.361 0.000
K08 Other disorders of teeth and supporting structures
0.639 0.361 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.639 0.361 0.000
M88 Paget's disease of bone [osteitis deformans]
0.639 0.361 0.000
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters
0.639 0.361 0.000
K27 Peptic ulcer, site unspecified
0.639 0.361 0.000
M25.9 Joint disorder, unspecified
0.639 0.361 0.000
M25.3 Other instability of joint
0.639 0.361 0.000
M25.2 Flail joint
0.639 0.361 0.000
M25.1 Fistula of joint
0.639 0.361 0.000
M25.0 Haemarthrosis
0.639 0.361 0.000
H05.8 Other disorders of orbit
0.639 0.361 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.638 0.361 0.000
S02.3 Fracture of orbital floor
0.638 0.362 0.000
K11.7 Disturbances of salivary secretion
0.638 0.362 0.000
K11.4 Fistula of salivary gland
0.638 0.362 0.000
K11.3 Abscess of salivary gland
0.638 0.362 0.000
K11.0 Atrophy of salivary gland
0.638 0.362 0.000
K11.5 Sialolithiasis
0.638 0.362 0.000
J30-J39 Other diseases of upper respiratory tract
0.637 0.363 0.000
J09-J18 Influenza and pneumonia
0.637 0.363 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.636 0.363 0.000
S48 Traumatic amputation of shoulder and upper arm
0.636 0.363 0.000
S45 Injury of blood vessels at shoulder and upper arm level
0.636 0.363 0.000
S44 Injury of nerves at shoulder and upper arm level
0.636 0.363 0.000
S41 Open wound of shoulder and upper arm
0.636 0.363 0.000
S47 Crushing injury of shoulder and upper arm
0.636 0.363 0.000
K26.4 Chronic or unspecified with haemorrhage
0.636 0.364 0.000
K12.0 Recurrent oral aphthae
0.636 0.364 0.000
W00-W19 Falls
0.635 0.365 0.000
H04.9 Disorder of lachrymal system, unspecified
0.635 0.365 0.000
H04.8 Other disorders of lachrymal system
0.635 0.365 0.000
H04.6 Other changes in lachrymal passages
0.635 0.365 0.000
H04.4 Chronic inflammation of lachrymal passages
0.635 0.365 0.000
H04.0 Dacryoadenitis
0.635 0.365 0.000
S70-S79 Injuries to the hip and thigh
0.635 0.365 0.000
S65 Injury of blood vessels at wrist and hand level
0.634 0.366 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.634 0.366 0.000
M23.80 Other internal derangements of knee (Multiple sites)
0.633 0.366 0.000
M54.19 Radiculopathy (Site unspecified)
0.633 0.367 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.632 0.368 0.000
M23.89 Other internal derangements of knee (Unspecified ligament or Unspecified meniscus)
0.631 0.369 0.000
K00 Disorders of tooth development and eruption
0.631 0.369 0.000
Chapter V Mental and behavioural disorders
0.631 0.369 0.000
S01.3 Open wound of ear
0.630 0.370 0.000
K31.7 Polyp of stomach and duodenum
0.630 0.370 0.000
M23.1 Discoid meniscus (congenital)
0.630 0.370 0.000
M23.0 Cystic meniscus
0.630 0.370 0.000
M54.5 Low back pain
0.630 0.370 0.000
B50 Plasmodium falciparum malaria
0.630 0.370 0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot
0.630 0.370 0.000
K01.0 Embedded teeth
0.629 0.371 0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere
0.629 0.371 0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere
0.629 0.371 0.000
H17 Corneal scars and opacities
0.629 0.371 0.000
H15 Disorders of sclera
0.629 0.371 0.000
S82.10 Fracture of upper end of tibia (closed)
0.628 0.372 0.000
I86.4 Gastric varices
0.627 0.373 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.627 0.373 0.000
I82 Other venous embolism and thrombosis
0.626 0.373 0.000
M25.66 Stiffness of joint, not elsewhere classified (Lower leg)
0.626 0.374 0.000
I99 Other and unspecified disorders of circulatory system
0.626 0.374 0.000
M90 Osteopathies in diseases classified elsewhere
0.626 0.374 0.000
K70.4 Alcoholic hepatic failure
0.626 0.374 0.000
S52.0 Fracture of upper end of ulna
0.626 0.374 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.626 0.374 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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