TreeWAS – Variant ID: rs117023793

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
# Top node	1.000	0.000
Chapter IX Diseases of the circulatory system	1.000	0.000
Chapter VI Diseases of the nervous system	1.000	0.000
Chapter I Certain infectious and parasitic diseases	0.999	0.001
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.997	0.003
I70-I79 Diseases of arteries, arterioles and capillaries	0.997	0.003
Chapter IV Endocrine, nutritional and metabolic diseases	0.997	0.003
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.997	0.003
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	0.994	0.006
B95-B98 Bacterial, viral and other infectious agents	0.993	0.007
G40-G47 Episodic and paroxysmal disorders	0.991	0.009
I30-I52 Other forms of heart disease	0.989	0.011
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters	0.986	0.014
G47 Sleep disorders	0.984	0.016
I73 Other peripheral vascular diseases	0.979	0.021
Chapter X Diseases of the respiratory system	0.979	0.021
G50-G59 Nerve, nerve root and plexus disorders	0.978	0.022
M50-M54 Other dorsopathies	0.978	0.022
R70-R79 Abnormal findings on examination of blood, without diagnosis	0.977	0.023
G47.3 Sleep apnoea	0.975	0.025
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems	0.975	0.025
I60-I69 Cerebrovascular diseases	0.974	0.026
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.970	0.030
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.968	0.032
E70-E90 Metabolic disorders	0.966	0.034
G51 Facial nerve disorders	0.964	0.036
R79 Other abnormal findings of blood chemistry	0.960	0.040
M54 Dorsalgia	0.959	0.041
G51.0 Bell's palsy	0.950	0.050
I35 Nonrheumatic aortic valve disorders	0.942	0.058
I73.0 Raynaud's syndrome	0.942	0.058
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.941	0.059
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters	0.941	0.059
I63 Cerebral infarction	0.941	0.059
E83 Disorders of mineral metabolism	0.938	0.062
I51 Complications and ill-defined descriptions of heart disease	0.933	0.067
E87 Other disorders of fluid, electrolyte and acid-base balance	0.933	0.067
E20-E35 Disorders of other endocrine glands	0.932	0.068
Chapter XX External causes of morbidity and mortality	0.930	0.070
I84 Haemorrhoids	0.923	0.077
R79.8 Other specified abnormal findings of blood chemistry	0.922	0.078
M40-M43 Deforming dorsopathies	0.921	0.079
M54.5 Low back pain	0.920	0.080
T81 Complications of procedures, not elsewhere classified	0.912	0.088
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.912	0.088
I71 Aortic aneurysm and dissection	0.911	0.089
I86 Varicose veins of other sites	0.909	0.091
J95-J99 Other diseases of the respiratory system	0.899	0.101
E83.4 Disorders of magnesium metabolism	0.897	0.103
Chapter XXII Codes for special purposes	0.897	0.103
T81.4 Infection following a procedure, not elsewhere classified	0.895	0.105
R79.0 Abnormal level of blood mineral	0.886	0.113
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour	0.886	0.114
M54.59 Low back pain (Site unspecified)	0.884	0.116
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.882	0.118
I73.9 Peripheral vascular disease, unspecified	0.880	0.120
M80-M85 Disorders of bone density and structure	0.877	0.123
I63.9 Cerebral infarction, unspecified	0.876	0.124
B95.7 Other staphylococcus as the cause of diseases classified to other chapters	0.874	0.126
R27 Other lack of coordination	0.873	0.127
J30-J39 Other diseases of upper respiratory tract	0.872	0.128
T36-T50 Poisoning by drugs, medicaments and biological substances	0.872	0.128
S90-S99 Injuries to the ankle and foot	0.871	0.129
I47 Paroxysmal tachycardia	0.871	0.129
G62 Other polyneuropathies	0.870	0.130
R26 Abnormalities of gait and mobility	0.869	0.131
M20-M25 Other joint disorders	0.868	0.132
I35.0 Aortic (valve) stenosis	0.868	0.132
B95.4 Other streptococcus as the cause of diseases classified to other chapters	0.865	0.135
E40-E46 Malnutrition	0.860	0.140
I84.1 Internal haemorrhoids with other complications	0.858	0.142
M86-M90 Other osteopathies	0.857	0.143
I86.1 Scrotal varices	0.856	0.144
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.856	0.144
T51 Toxic effect of alcohol	0.851	0.149
E10-E14 Diabetes mellitus	0.850	0.150
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.843	0.157
R10-R19 Symptoms and signs involving the digestive system and abdomen	0.843	0.157
J09-J18 Influenza and pneumonia	0.843	0.157
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.842	0.158
R11 Nausea and vomiting	0.841	0.159
I64 Stroke, not specified as haemorrhage or infarction	0.838	0.162
I31 Other diseases of pericardium	0.837	0.162
R42 Dizziness and giddiness	0.837	0.163
I51.7 Cardiomegaly	0.834	0.166
M54.4 Lumbago with sciatica	0.833	0.167
M54.56 Low back pain (Lumbar region)	0.830	0.170
T87 Complications peculiar to reattachment and amputation	0.828	0.172
B35-B49 Mycoses	0.828	0.172
E83.3 Disorders of phosphorus metabolism	0.827	0.173
G62.9 Polyneuropathy, unspecified	0.827	0.173
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.827	0.173
G20-G26 Extrapyramidal and movement disorders	0.825	0.175
I84.4 External haemorrhoids with other complications	0.822	0.178
E87.6 Hypokalaemia	0.822	0.178
R72 Abnormality of white blood cells, not elsewhere classified	0.822	0.178
A30-A49 Other bacterial diseases	0.821	0.179
I50 Heart failure	0.820	0.180
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.820	0.180
R29 Other symptoms and signs involving the nervous and musculoskeletal systems	0.818	0.182
M31 Other necrotising vasculopathies	0.818	0.182
I44 Atrioventricular and left bundle-branch block	0.817	0.183
S30 Superficial injury of abdomen, lower back and pelvis	0.816	0.184
M43 Other deforming dorsopathies	0.815	0.185
G55 Nerve root and plexus compressions in diseases classified elsewhere	0.812	0.188
T66-T78 Other and unspecified effects of external causes	0.810	0.190
I70 Atherosclerosis	0.809	0.191
T79-T79 Certain early complications of trauma	0.809	0.191
E87.7 Fluid overload	0.809	0.191
J60-J70 Lung diseases due to external agents	0.808	0.191
I51.8 Other ill-defined heart diseases	0.808	0.192
W00-W19 Falls	0.807	0.193
I35.1 Aortic (valve) insufficiency	0.805	0.195
E87.3 Alkalosis	0.805	0.195
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.804	0.196
E11 Non-insulin-dependent diabetes mellitus	0.804	0.196
I47.2 Ventricular tachycardia	0.803	0.197
B25-B34 Other viral diseases	0.803	0.197
M51 Other intervertebral disk disorders	0.803	0.197
T51.0 Ethanol	0.802	0.197
I74 Arterial embolism and thrombosis	0.801	0.199
R25 Abnormal involuntary movements	0.798	0.202
E50-E64 Other nutritional deficiencies	0.797	0.203
E27 Other disorders of adrenal gland	0.796	0.204
R80-R82 Abnormal findings on examination of urine, without diagnosis	0.795	0.204
G47.9 Sleep disorder, unspecified	0.795	0.205
E29 Testicular dysfunction	0.794	0.206
J00-J06 Acute upper respiratory infections	0.793	0.207
T81.3 Disruption of operation wound, not elsewhere classified	0.790	0.210
M65-M68 Disorders of synovium and tendon	0.790	0.210
B98 Other specified infectious agents as the cause of diseases classified to other chapters	0.790	0.210
I42 Cardiomyopathy	0.790	0.210
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.789	0.211
R26.8 Other and unspecified abnormalities of gait and mobility	0.789	0.211
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.787	0.213
I72 Other aneurysm	0.786	0.214
M41 Scoliosis	0.786	0.214
Chapter XV Pregnancy, childbirth and the puerperium	0.784	0.216
A00-A09 Intestinal infectious diseases	0.784	0.216
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.784	0.216
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.784	0.216
I84.6 Residual haemorrhoidal skin tags	0.783	0.217
M54.3 Sciatica	0.783	0.217
J98 Other respiratory disorders	0.783	0.217
R27.0 Ataxia, unspecified	0.782	0.218
J34 Other disorders of nose and nasal sinuses	0.782	0.218
I63.3 Cerebral infarction due to thrombosis of cerebral arteries	0.780	0.220
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters	0.777	0.223
I84.7 Unspecified thrombosed haemorrhoids	0.776	0.224
R50-R69 General symptoms and signs	0.775	0.225
M31.6 Other giant cell arteritis	0.775	0.225
S20-S29 Injuries to the thorax	0.774	0.226
J80-J84 Other respiratory diseases principally affecting the interstitium	0.774	0.226
E87.1 Hypo-osmolality and hyponatraemia	0.773	0.227
M54.8 Other dorsalgia	0.771	0.229
G54 Nerve root and plexus disorders	0.771	0.229
G51.9 Disorder of facial nerve, unspecified	0.770	0.230
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.769	0.231
G00-G09 Inflammatory diseases of the central nervous system	0.768	0.232
S70-S79 Injuries to the hip and thigh	0.766	0.234
G59 Mononeuropathy in diseases classified elsewhere	0.764	0.236
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.762	0.238
E46 Unspecified protein-energy malnutrition	0.762	0.238
B02 Zoster [herpes zoster]	0.762	0.238
I35.8 Other aortic valve disorders	0.760	0.240
J38 Diseases of vocal cords and larynx, not elsewhere classified	0.760	0.240
I05-I09 Chronic rheumatic heart diseases	0.758	0.242
G45 Transient cerebral ischaemic attacks and related syndromes	0.757	0.243
O00-O08 Pregnancy with abortive outcome	0.756	0.244
G53 Cranial nerve disorders in diseases classified elsewhere	0.754	0.246
G47.0 Disorders of initiating and maintaining sleep [insomnias]	0.752	0.247
U80 Agent resistant to penicillin and related antibiotics	0.751	0.249
I77 Other disorders of arteries and arterioles	0.750	0.250
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters	0.750	0.250
G41 Status epilepticus	0.750	0.250
T81.7 Vascular complications following a procedure, not elsewhere classified	0.748	0.252
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.748	0.252
I50.0 Congestive heart failure	0.747	0.253
B96 Other bacterial agents as the cause of diseases classified to other chapters	0.746	0.254
M84 Disorders of continuity of bone	0.746	0.254
W20-W49 Exposure to inanimate mechanical forces	0.745	0.255
R29.6 Tendency to fall, not elsewhere classified	0.745	0.255
G55.1 Nerve root and plexus compressions in intervertebral disk disorders	0.744	0.256
G90-G99 Other disorders of the nervous system	0.744	0.256
E73 Lactose intolerance	0.744	0.256
M81 Osteoporosis without pathological fracture	0.743	0.257
B20-B24 Human immunodeficiency virus [HIV] disease	0.741	0.258
J34.3 Hypertrophy of nasal turbinates	0.741	0.259
A50-A64 Infections with a predominantly sexual mode of transmission	0.740	0.260
S99 Other and unspecified injuries of ankle and foot	0.740	0.260
I81 Portal vein thrombosis	0.740	0.260
G40 Epilepsy	0.739	0.261
I85 Oesophageal varices	0.739	0.261
Chapter II Neoplasms	0.739	0.261
G63 Polyneuropathy in diseases classified elsewhere	0.738	0.262
J13 Pneumonia due to Streptococcus pneumoniae	0.738	0.262
I89 Other non-infective disorders of lymphatic vessels and lymph nodes	0.737	0.263
G70-G73 Diseases of myoneural junction and muscle	0.736	0.263
G47.1 Disorders of excessive somnolence [hypersomnias]	0.736	0.264
B90-B94 Sequelae of infectious and parasitic diseases	0.735	0.265
G20 Parkinson's disease	0.734	0.266
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters	0.734	0.266
R70 Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity	0.733	0.267
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.733	0.267
J99 Respiratory disorders in diseases classified elsewhere	0.731	0.269
M43.1 Spondylolisthesis	0.730	0.270
G35-G37 Demyelinating diseases of the central nervous system	0.730	0.270
I84.3 External thrombosed haemorrhoids	0.730	0.270
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.729	0.271
M54.49 Lumbago with sciatica (Site unspecified)	0.729	0.271
T87.4 Infection of amputation stump	0.728	0.272
I71.3 Abdominal aortic aneurysm, ruptured	0.727	0.273
I69 Sequelae of cerebrovascular disease	0.727	0.273
S30.2 Contusion of external genital organs	0.727	0.273
T88 Other complications of surgical and medical care, not elsewhere classified	0.726	0.274
I51.4 Myocarditis, unspecified	0.725	0.275
M25 Other joint disorders, not elsewhere classified	0.723	0.277
E24 Cushing's syndrome	0.723	0.277
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.722	0.278
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters	0.722	0.278
R44 Other symptoms and signs involving general sensations and perceptions	0.721	0.279
I60 Subarachnoid haemorrhage	0.721	0.279
E22 Hyperfunction of pituitary gland	0.721	0.279
A80-A89 Viral infections of the central nervous system	0.720	0.279
R74 Abnormal serum enzyme levels	0.720	0.280
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.719	0.281
V80-V89 Other land transport accidents	0.719	0.281
M54.1 Radiculopathy	0.719	0.281
I00-I02 Acute rheumatic fever	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
M05-M14 Inflammatory polyarthropathies	0.717	0.283
B99-B99 Other infectious diseases	0.716	0.284
B85-B89 Pediculosis, acariasis and other infestations	0.716	0.284
B65-B83 Helminthiases	0.716	0.284
B50-B64 Protozoal diseases	0.716	0.284
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.716	0.284
A75-A79 Rickettsioses	0.716	0.284
A70-A74 Other diseases caused by chlamydiae	0.716	0.284
A65-A69 Other spirochaetal diseases	0.716	0.284
A20-A28 Certain zoonotic bacterial diseases	0.716	0.284
A15-A19 Tuberculosis	0.716	0.284
R15 Faecal incontinence	0.716	0.284
T86 Failure and rejection of transplanted organs and tissues	0.716	0.284
R76 Other abnormal immunological findings in serum	0.716	0.284
J98.0 Diseases of bronchus, not elsewhere classified	0.716	0.284
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue	0.715	0.285
M00-M03 Infectious arthropathies	0.715	0.285
G61 Inflammatory polyneuropathy	0.715	0.285
M91-M94 Chondropathies	0.715	0.285
M60-M63 Disorders of muscles	0.715	0.285
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.715	0.285
M24 Other specific joint derangements	0.715	0.285
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis	0.715	0.285
T33-T35 Frostbite	0.715	0.285
T26-T28 Burns and corrosions confined to eye and internal organs	0.715	0.285
T20-T25 Burns and corrosions of external body surface, specified by site	0.715	0.285
T00-T07 Injuries involving multiple body regions	0.715	0.285
S10-S19 Injuries to the neck	0.715	0.285
G30-G32 Other degenerative diseases of the nervous system	0.714	0.286
J61 Pneumoconiosis due to asbestos and other mineral fibres	0.714	0.286
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.714	0.286
A09 Diarrhoea and gastro-enteritis of presumed infectious origin	0.714	0.286
R95-R99 Ill-defined and unknown causes of mortality	0.713	0.287
T80 Complications following infusion, transfusion and therapeutic injection	0.713	0.287
D10-D36 Benign neoplasms	0.712	0.288
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters	0.712	0.288
G46 Vascular syndromes of brain in cerebrovascular diseases	0.710	0.289
W50-W64 Exposure to animate mechanical forces	0.710	0.290
I62 Other nontraumatic intracranial haemorrhage	0.710	0.290
I52 Other heart disorders in diseases classified elsewhere	0.709	0.291
I48 Atrial fibrillation and flutter	0.709	0.291
I43 Cardiomyopathy in diseases classified elsewhere	0.709	0.291
I41 Myocarditis in diseases classified elsewhere	0.709	0.291
I40 Acute myocarditis	0.709	0.291
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.709	0.291
I37 Pulmonary valve disorders	0.709	0.291
I36 Nonrheumatic tricuspid valve disorders	0.709	0.291
I32 Pericarditis in diseases classified elsewhere	0.709	0.291
J95 Postprocedural respiratory disorders, not elsewhere classified	0.709	0.291
X60-X84 Intentional self-harm	0.706	0.294
G47.8 Other sleep disorders	0.706	0.294
G47.4 Narcolepsy and cataplexy	0.706	0.294
G47.2 Disorders of the sleep-wake schedule	0.706	0.294
R63 Symptoms and signs concerning food and fluid intake	0.705	0.295
Q20-Q28 Congenital malformations of the circulatory system	0.704	0.296
B00 Herpesviral [herpes simplex] infections	0.704	0.296
I95-I99 Other and unspecified disorders of the circulatory system	0.703	0.297
V10-V19 Pedal cyclist injured in transport accident	0.703	0.297
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.703	0.297
M51.2 Other specified intervertebral disk displacement	0.703	0.297
I73.8 Other specified peripheral vascular diseases	0.702	0.298
I73.1 Thromboangiitis obliterans [Buerger]	0.702	0.298
Y51 Drugs primarily affecting the autonomic nervous system	0.702	0.298
G52 Disorders of other cranial nerves	0.701	0.299
M53 Other dorsopathies, not elsewhere classified	0.701	0.299
S90 Superficial injury of ankle and foot	0.700	0.300
R78 Findings of drugs and other substances, not normally found in blood	0.700	0.300
R77 Other abnormalities of plasma proteins	0.700	0.300
R75 Laboratory evidence of human immunodeficiency virus [HIV]	0.700	0.300
R71 Abnormality of red blood cells	0.700	0.300
G58 Other mononeuropathies	0.700	0.300
I86.4 Gastric varices	0.699	0.301
E11.4 With neurological complications	0.699	0.301
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.699	0.301
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.698	0.301
I68 Cerebrovascular disorders in diseases classified elsewhere	0.698	0.302
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.698	0.302
G60 Hereditary and idiopathic neuropathy	0.698	0.302
I44.2 Atrioventricular block, complete	0.697	0.303
M21 Other acquired deformities of limbs	0.697	0.303
E28 Ovarian dysfunction	0.696	0.304
E11.8 With unspecified complications	0.696	0.304
T90 Sequelae of injuries of head	0.696	0.304
E29.1 Testicular hypofunction	0.696	0.304
I88 Nonspecific lymphadenitis	0.695	0.305
E23 Hypofunction and other disorders of pituitary gland	0.695	0.305
J36 Peritonsillar abscess	0.695	0.305
O02 Other abnormal products of conception	0.694	0.306
E16 Other disorders of pancreatic internal secretion	0.693	0.307
E85 Amyloidosis	0.693	0.307
E84 Cystic fibrosis	0.693	0.307
E79 Disorders of purine and pyrimidine metabolism	0.693	0.307
E77 Disorders of glycoprotein metabolism	0.693	0.307
E76 Disorders of glycosaminoglycan metabolism	0.693	0.307
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.693	0.307
E74 Other disorders of carbohydrate metabolism	0.693	0.307
E72 Other disorders of amino-acid metabolism	0.693	0.307
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.693	0.307
E70 Disorders of aromatic amino-acid metabolism	0.693	0.307
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.693	0.307
M54.6 Pain in thoracic spine	0.693	0.307
I84.2 Internal haemorrhoids without complication	0.692	0.308
J02 Acute pharyngitis	0.692	0.308
G51.8 Other disorders of facial nerve	0.691	0.309
G51.4 Facial myokymia	0.691	0.309
G51.3 Clonic hemifacial spasm	0.691	0.309
G51.2 Melkersson's syndrome	0.691	0.309
G51.1 Geniculate ganglionitis	0.691	0.309
M89 Other disorders of bone	0.691	0.309
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.690	0.310
E27.4 Other and unspecified adrenocortical insufficiency	0.690	0.310
I31.3 Pericardial effusion (noninflammatory)	0.690	0.310
M41.9 Scoliosis, unspecified	0.689	0.311
I82 Other venous embolism and thrombosis	0.688	0.311
M54.0 Panniculitis affecting regions of neck and back	0.687	0.312
B95.0 Streptococcus, group A, as the cause of diseases classified to other chapters	0.687	0.313
W19 Unspecified fall	0.686	0.314
I67 Other cerebrovascular diseases	0.685	0.315
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.684	0.315
B15-B19 Viral hepatitis	0.684	0.316
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure	0.684	0.316
M45-M49 Spondylopathies	0.682	0.318
B02.9 Zoster without complication	0.682	0.318
I38 Endocarditis, valve unspecified	0.679	0.321
G50 Disorders of trigeminal nerve	0.678	0.321
I70.2 Atherosclerosis of arteries of the extremities	0.675	0.325
G64 Other disorders of peripheral nervous system	0.675	0.325
T79 Certain early complications of trauma, not elsewhere classified	0.675	0.325
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic	0.674	0.325
I63.4 Cerebral infarction due to embolism of cerebral arteries	0.674	0.325
I63.1 Cerebral infarction due to embolism of precerebral arteries	0.674	0.325
I63.0 Cerebral infarction due to thrombosis of precerebral arteries	0.674	0.325
B97 Viral agents as the cause of diseases classified to other chapters	0.674	0.326
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.674	0.326
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified	0.674	0.326
J81 Pulmonary oedema	0.674	0.326
I47.9 Paroxysmal tachycardia, unspecified	0.673	0.327
R27.8 Other and unspecified lack of coordination	0.673	0.327
M86 Osteomyelitis	0.673	0.327
R53 Malaise and fatigue	0.673	0.327
E83.9 Disorder of mineral metabolism, unspecified	0.672	0.328
E83.8 Other disorders of mineral metabolism	0.672	0.328
E83.2 Disorders of zinc metabolism	0.672	0.328
E83.0 Disorders of copper metabolism	0.672	0.328
A09.9 Gastroenteritis and colitis of unspecified origin	0.672	0.328
U51 Admission status on psychiatric patients	0.671	0.329
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.671	0.329
I42.0 Dilated cardiomyopathy	0.671	0.329
M54.39 Sciatica (Site unspecified)	0.671	0.329
W02 Fall involving ice-skates, skis, roller-skates or skateboards	0.670	0.330
I30 Acute pericarditis	0.670	0.330
J90-J94 Other diseases of pleura	0.669	0.331
I51.6 Cardiovascular disease, unspecified	0.669	0.331
I51.5 Myocardial degeneration	0.669	0.331
I51.3 Intracardiac thrombosis, not elsewhere classified	0.669	0.331
I51.2 Rupture of papillary muscle, not elsewhere classified	0.669	0.331
I51.1 Rupture of chordae tendineae, not elsewhere classified	0.669	0.331
I51.0 Cardiac septal defect, acquired	0.669	0.331
I33 Acute and subacute endocarditis	0.669	0.331
E87.4 Mixed disorder of acid-base balance	0.669	0.331
E35 Disorders of endocrine glands in diseases classified elsewhere	0.668	0.332
E34 Other endocrine disorders	0.668	0.332
E32 Diseases of thymus	0.668	0.332
E31 Polyglandular dysfunction	0.668	0.332
E30 Disorders of puberty, not elsewhere classified	0.668	0.332
E26 Hyperaldosteronism	0.668	0.332
E25 Adrenogenital disorders	0.668	0.332
E20 Hypoparathyroidism	0.668	0.332
B37 Candidiasis	0.668	0.332
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.667	0.333
Y35-Y36 Legal intervention and operations of war	0.667	0.333
Y10-Y34 Event of undetermined intent	0.667	0.333
Y00-Y09 Assault	0.667	0.333
X85-X99 Assault	0.667	0.333
X58-X59 Accidental exposure to other and unspecified factors	0.667	0.333
X50-X57 Overexertion, travel and privation	0.667	0.333
X40-X49 Accidental poisoning by and exposure to noxious substances	0.667	0.333
X30-X39 Exposure to forces of nature	0.667	0.333
X20-X29 Contact with venomous animals and plants	0.667	0.333
X10-X19 Contact with heat and hot substances	0.667	0.333
X00-X09 Exposure to smoke, fire and flames	0.667	0.333
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.667	0.333
W75-W84 Other accidental threats to breathing	0.667	0.333
W65-W74 Accidental drowning and submersion	0.667	0.333
V98-V99 Other and unspecified transport accidents	0.667	0.333
V95-V97 Air and space transport accidents	0.667	0.333
V90-V94 Water transport accidents	0.667	0.333
V70-V79 Bus occupant injured in transport accident	0.667	0.333
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.667	0.333
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.667	0.333
V40-V49 Car occupant injured in transport accident	0.667	0.333
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.667	0.333
V01-V09 Pedestrian injured in transport accident	0.667	0.333
I84.5 External haemorrhoids without complication	0.667	0.333
E11.5 With peripheral circulatory complications	0.666	0.334
R26.2 Difficulty in walking, not elsewhere classified	0.666	0.334
E11.0 With coma	0.665	0.335
D18 Haemangioma and lymphangioma, any site	0.665	0.335
E88 Other metabolic disorders	0.664	0.336
I31.9 Disease of pericardium, unspecified	0.664	0.336
C64-C68 Malignant neoplasms of urinary tract	0.664	0.336
B34 Viral infection of unspecified site	0.663	0.337
G80-G83 Cerebral palsy and other paralytic syndromes	0.662	0.338
I84.0 Internal thrombosed haemorrhoids	0.662	0.338
T92 Sequelae of injuries of upper limb	0.662	0.338
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.661	0.339
M42 Spinal osteochondrosis	0.660	0.340
M40 Kyphosis and lordosis	0.660	0.340
R20 Disturbances of skin sensation	0.660	0.340
M54.55 Low back pain (Thoracolumbar region)	0.659	0.340
M54.54 Low back pain-Thoracic	0.659	0.340
M54.53 Low back pain-Cervicothoracic	0.659	0.340
M54.52 Low back pain-Cervical	0.659	0.340
M54.51 Low back pain-Occipit-atl-axl	0.659	0.340
I78 Diseases of capillaries	0.659	0.341
J39 Other diseases of upper respiratory tract	0.659	0.341
T63 Toxic effect of contact with venomous animals	0.659	0.341
M54.2 Cervicalgia	0.659	0.341
M54.50 Low back pain (Multiple sites in spine)	0.657	0.343
R52 Pain, not elsewhere classified	0.656	0.344
U80.0 Penicillin resistant agent	0.655	0.345
O03 Spontaneous abortion	0.655	0.345
I61 Intracerebral haemorrhage	0.654	0.346
T81.9 Unspecified complication of procedure	0.654	0.346
T81.6 Acute reaction to foreign substance accidentally left during a procedure	0.654	0.346
T81.1 Shock during or resulting from a procedure, not elsewhere classified	0.654	0.346
T65 Toxic effect of other and unspecified substances	0.654	0.346
T62 Toxic effect of other noxious substances eaten as food	0.654	0.346
T61 Toxic effect of noxious substances eaten as seafood	0.654	0.346
T60 Toxic effect of pesticides	0.654	0.346
T59 Toxic effect of other gases, fumes and vapours	0.654	0.346
T57 Toxic effect of other inorganic substances	0.654	0.346
T56 Toxic effect of metals	0.654	0.346
T54 Toxic effect of corrosive substances	0.654	0.346
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone	0.654	0.346
T52 Toxic effect of organic solvents	0.654	0.346
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants	0.654	0.346
T58 Toxic effect of carbon monoxide	0.654	0.346
T55 Toxic effect of soaps and detergents	0.654	0.346
I71.8 Aortic aneurysm of unspecified site, ruptured	0.653	0.347
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.653	0.347
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.653	0.347
I71.1 Thoracic aortic aneurysm, ruptured	0.653	0.347
I71.0 Dissection of aorta [any part]	0.653	0.347
I86.8 Varicose veins of other specified sites	0.652	0.348
I86.3 Vulval varices	0.652	0.348
I86.2 Pelvic varices	0.652	0.348
I86.0 Sublingual varices	0.652	0.348
M43.16 Spondylolisthesis (Lumbar region)	0.652	0.348
Q80-Q89 Other congenital malformations	0.651	0.349
T75 Effects of other external causes	0.650	0.350
R45 Symptoms and signs involving emotional state	0.650	0.350
O02.1 Missed abortion	0.650	0.350
I51.9 Heart disease, unspecified	0.650	0.350
J37 Chronic laryngitis and laryngotracheitis	0.649	0.351
I46 Cardiac arrest	0.649	0.351
A41 Other septicaemia	0.649	0.351
B44 Aspergillosis	0.649	0.351
J38.1 Polyp of vocal cord and larynx	0.648	0.351
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.648	0.352
Chapter VIII Diseases of the ear and mastoid process	0.648	0.352
E83.5 Disorders of calcium metabolism	0.648	0.352
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.647	0.352
A49 Bacterial infection of unspecified site	0.647	0.353
M81.9 Osteoporosis, unspecified	0.647	0.353
T15-T19 Effects of foreign body entering through natural orifice	0.647	0.353
M35 Other systemic involvement of connective tissue	0.647	0.353
J14 Pneumonia due to Haemophilus influenzae	0.647	0.353
G44 Other headache syndromes	0.646	0.354
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.646	0.354

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations