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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs117050257
log Bayes Factor = 8.34736
Chromosome 11   position 28,231,197  (GRCh37) Explore rs117050257 on Ensembl!
Variant rs117050257 is part of Cluster X0080

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
M50-M54 Other dorsopathies
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
M54 Dorsalgia
0.999 0.001 0.000
Chapter IX Diseases of the circulatory system
0.999 0.001 0.000
I60-I69 Cerebrovascular diseases
0.998 0.002 0.000
M54.2 Cervicalgia
0.989 0.011 0.000
Chapter VI Diseases of the nervous system
0.989 0.011 0.000
I30-I52 Other forms of heart disease
0.986 0.014 0.000
M51 Other intervertebral disk disorders
0.984 0.016 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.979 0.021 0.000
M45-M49 Spondylopathies
0.979 0.021 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.977 0.023 0.000
M54.22 Cervicalgia (Cervical region)
0.976 0.024 0.000
D50-D53 Nutritional anaemias
0.966 0.034 0.000
D50.9 Iron deficiency anaemia, unspecified
0.965 0.035 0.000
S60-S69 Injuries to the wrist and hand
0.964 0.036 0.000
D50 Iron deficiency anaemia
0.964 0.036 0.000
M48 Other spondylopathies
0.963 0.037 0.000
G40-G47 Episodic and paroxysmal disorders
0.956 0.044 0.000
Chapter XX External causes of morbidity and mortality
0.956 0.044 0.000
M15-M19 Arthrosis
0.952 0.048 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.951 0.049 0.000
M51.2 Other specified intervertebral disk displacement
0.951 0.049 0.000
M48.0 Spinal stenosis
0.951 0.049 0.000
S61 Open wound of wrist and hand
0.948 0.052 0.000
M54.1 Radiculopathy
0.946 0.054 0.000
I51 Complications and ill-defined descriptions of heart disease
0.943 0.057 0.000
M54.4 Lumbago with sciatica
0.942 0.058 0.000
T92 Sequelae of injuries of upper limb
0.942 0.058 0.000
M86-M90 Other osteopathies
0.939 0.061 0.000
I63 Cerebral infarction
0.939 0.061 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.935 0.065 0.000
T66-T78 Other and unspecified effects of external causes
0.934 0.066 0.000
M19 Other arthrosis
0.931 0.069 0.000
S61.9 Open wound of wrist and hand, part unspecified
0.923 0.077 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.921 0.079 0.000
I35 Nonrheumatic aortic valve disorders
0.920 0.080 0.000
I60 Subarachnoid haemorrhage
0.916 0.084 0.000
S10-S19 Injuries to the neck
0.915 0.085 0.000
Chapter XXI Factors influencing health status and contact with health services
0.911 0.089 0.000
M50 Cervical disk disorders
0.906 0.094 0.000
I51.8 Other ill-defined heart diseases
0.906 0.094 0.000
M48.06 Spinal stenosis (Lumbar region)
0.905 0.095 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.903 0.097 0.000
M54.46 Lumbago with sciatica (Lumbar region)
0.901 0.099 0.000
M51.0 Lumbar and other intervertebral disk disorders with myelopathy
0.899 0.101 0.000
G45.9 Transient cerebral ischaemic attack, unspecified
0.898 0.102 0.000
Z48 Other surgical follow-up care
0.896 0.104 0.000
Z48.8 Other specified surgical follow-up care
0.895 0.105 0.000
I61 Intracerebral haemorrhage
0.893 0.107 0.000
M19.0 Primary arthrosis of other joints
0.890 0.110 0.000
W20-W49 Exposure to inanimate mechanical forces
0.889 0.111 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.888 0.112 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.887 0.113 0.000
I69 Sequelae of cerebrovascular disease
0.884 0.116 0.000
M54.17 Radiculopathy (Lumbosacral region)
0.882 0.118 0.000
I33 Acute and subacute endocarditis
0.878 0.122 0.000
S90-S99 Injuries to the ankle and foot
0.873 0.126 0.000
M48.09 Spinal stenosis (Site unspecified)
0.873 0.127 0.000
T78 Adverse effects, not elsewhere classified
0.871 0.129 0.000
M18 Arthrosis of first carpometacarpal joint
0.870 0.130 0.000
I67 Other cerebrovascular diseases
0.863 0.137 0.000
Chapter VIII Diseases of the ear and mastoid process
0.861 0.139 0.000
G44 Other headache syndromes
0.860 0.140 0.000
I44 Atrioventricular and left bundle-branch block
0.860 0.140 0.000
G90-G99 Other disorders of the nervous system
0.859 0.141 0.000
I63.9 Cerebral infarction, unspecified
0.859 0.141 0.000
I49 Other cardiac arrhythmias
0.858 0.142 0.000
Y43 Primarily systemic agents
0.855 0.145 0.000
Y40 Systemic antibiotics
0.854 0.146 0.000
S50-S59 Injuries to the elbow and forearm
0.851 0.149 0.000
M89 Other disorders of bone
0.849 0.151 0.000
Q50-Q56 Congenital malformations of genital organs
0.847 0.153 0.000
M50.1 Cervical disk disorder with radiculopathy
0.846 0.154 0.000
M19.9 Arthrosis, unspecified
0.843 0.157 0.000
S70-S79 Injuries to the hip and thigh
0.843 0.157 0.000
S80-S89 Injuries to the knee and lower leg
0.842 0.158 0.000
M54.29 Cervicalgia-Site unspe
0.841 0.159 0.000
T91 Sequelae of injuries of neck and trunk
0.829 0.171 0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.825 0.175 0.000
M54.5 Low back pain
0.825 0.175 0.000
W22 Striking against or struck by other objects
0.824 0.176 0.000
M54.16 Radiculopathy (Lumbar region)
0.824 0.176 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.824 0.176 0.000
D55-D59 Haemolytic anaemias
0.823 0.177 0.000
H65-H75 Diseases of middle ear and mastoid
0.822 0.178 0.000
I05-I09 Chronic rheumatic heart diseases
0.821 0.179 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.820 0.180 0.000
S61.0 Open wound of finger(s) without damage to nail
0.817 0.183 0.000
S12 Fracture of neck
0.816 0.184 0.000
Q60-Q64 Congenital malformations of the urinary system
0.814 0.186 0.000
T92.1 Sequelae of fracture of arm
0.813 0.187 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.812 0.187 0.000
G82 Paraplegia and tetraplegia
0.811 0.189 0.000
M80-M85 Disorders of bone density and structure
0.811 0.189 0.000
I62 Other nontraumatic intracranial haemorrhage
0.810 0.190 0.000
I60.9 Subarachnoid haemorrhage, unspecified
0.806 0.194 0.000
T78.4 Allergy, unspecified
0.805 0.195 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.804 0.196 0.000
I33.0 Acute and subacute infective endocarditis
0.801 0.199 0.000
I61.9 Intracerebral haemorrhage, unspecified
0.798 0.202 0.000
Y43.3 Other antineoplastic drugs
0.798 0.202 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.796 0.204 0.000
G40 Epilepsy
0.794 0.206 0.000
M86 Osteomyelitis
0.794 0.206 0.000
I35.0 Aortic (valve) stenosis
0.793 0.207 0.000
I60.2 Subarachnoid haemorrhage from anterior communicating artery
0.793 0.207 0.000
I69.3 Sequelae of cerebral infarction
0.793 0.207 0.000
M48.02 Spinal stenosis (Cervical region)
0.788 0.212 0.000
I37 Pulmonary valve disorders
0.786 0.214 0.000
T92.3 Sequelae of dislocation, sprain and strain of upper limb
0.785 0.215 0.000
M60-M63 Disorders of muscles
0.785 0.215 0.000
I67.9 Cerebrovascular disease, unspecified
0.784 0.216 0.000
W22.9 Unspecified place
0.778 0.222 0.000
G06 Intracranial and intraspinal abscess and granuloma
0.778 0.222 0.000
T92.9 Sequelae of unspecified injury of upper limb
0.775 0.225 0.000
M70-M79 Other soft tissue disorders
0.775 0.225 0.000
Z43 Attention to artificial openings
0.773 0.227 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.773 0.227 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.772 0.228 0.000
S82 Fracture of lower leg, including ankle
0.771 0.229 0.000
Q80-Q89 Other congenital malformations
0.769 0.231 0.000
M19.02 Primary arthrosis of other joints (Upper arm)
0.768 0.232 0.000
T78.2 Anaphylactic shock, unspecified
0.767 0.233 0.000
M45 Ankylosing spondylitis
0.765 0.235 0.000
I35.8 Other aortic valve disorders
0.765 0.235 0.000
S19 Other and unspecified injuries of neck
0.762 0.238 0.000
M91-M94 Chondropathies
0.762 0.238 0.000
I49.0 Ventricular fibrillation and flutter
0.759 0.241 0.000
M87 Osteonecrosis
0.756 0.244 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.756 0.244 0.000
M19.01 Primary arthrosis of other joints (Shoulder region)
0.756 0.244 0.000
S50 Superficial injury of forearm
0.756 0.244 0.000
I49.5 Sick sinus syndrome
0.755 0.245 0.000
V40-V49 Car occupant injured in transport accident
0.753 0.246 0.000
S61.1 Open wound of finger(s) with damage to nail
0.753 0.247 0.000
T92.5 Sequelae of injury of muscle and tendon of upper limb
0.752 0.248 0.000
Z45 Adjustment and management of implanted device
0.752 0.248 0.000
T79-T79 Certain early complications of trauma
0.752 0.248 0.000
M18.9 Arthrosis of first carpometacarpal joint, unspecified
0.752 0.248 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.751 0.249 0.000
M19.04 Primary arthrosis of other joints (Hand)
0.751 0.249 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.749 0.251 0.000
M19.91 Arthrosis, unspecified (Shoulder region)
0.749 0.251 0.000
Y44 Agents primarily affecting blood constituents
0.747 0.253 0.000
T90 Sequelae of injuries of head
0.747 0.253 0.000
G95 Other diseases of spinal cord
0.746 0.254 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.745 0.255 0.000
H65 Nonsuppurative otitis media
0.744 0.256 0.000
G44.4 Drug-induced headache, not elsewhere classified
0.743 0.257 0.000
M19.93 Arthrosis, unspecified (Forearm)
0.742 0.258 0.000
T93 Sequelae of injuries of lower limb
0.742 0.258 0.000
M89.9 Disorder of bone, unspecified
0.741 0.259 0.000
G82.2 Paraplegia, unspecified
0.740 0.259 0.000
Y40.8 Other systemic antibiotics
0.739 0.261 0.000
W44 Foreign body entering into or through eye or natural orifice
0.738 0.262 0.000
Q61 Cystic kidney disease
0.737 0.263 0.000
S60 Superficial injury of wrist and hand
0.735 0.265 0.000
M18.1 Other primary arthrosis of first carpometacarpal joint
0.735 0.265 0.000
M51.9 Intervertebral disk disorder, unspecified
0.735 0.265 0.000
D80-D89 Certain disorders involving the immune mechanism
0.735 0.265 0.000
Q51 Congenital malformations of uterus and cervix
0.734 0.265 0.000
T68 Hypothermia
0.734 0.266 0.000
Z47 Other orthopaedic follow-up care
0.734 0.266 0.000
I44.2 Atrioventricular block, complete
0.733 0.267 0.000
Z52 Donors of organs and tissues
0.732 0.268 0.000
I38 Endocarditis, valve unspecified
0.732 0.268 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.732 0.268 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.731 0.268 0.000
I10-I15 Hypertensive diseases
0.730 0.270 0.000
Z42 Follow-up care involving plastic surgery
0.730 0.270 0.000
G41 Status epilepticus
0.729 0.271 0.000
S64 Injury of nerves at wrist and hand level
0.729 0.271 0.000
I51.7 Cardiomegaly
0.728 0.272 0.000
T92.2 Sequelae of fracture at wrist and hand level
0.727 0.273 0.000
M19.03 Primary arthrosis of other joints (Forearm)
0.726 0.274 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.726 0.274 0.000
M40-M43 Deforming dorsopathies
0.725 0.274 0.000
I63.8 Other cerebral infarction
0.725 0.275 0.000
S12.1 Fracture of second cervical vertebra
0.724 0.276 0.000
M47 Spondylosis
0.723 0.277 0.000
S82.2 Fracture of shaft of tibia
0.723 0.277 0.000
Y00-Y09 Assault
0.720 0.280 0.000
S20-S29 Injuries to the thorax
0.719 0.281 0.000
M54.6 Pain in thoracic spine
0.718 0.281 0.000
I30 Acute pericarditis
0.718 0.282 0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.718 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
M54.8 Other dorsalgia
0.716 0.283 0.000
M54.0 Panniculitis affecting regions of neck and back
0.716 0.283 0.000
M48.00 Spinal stenosis (Multiple sites in spine)
0.716 0.284 0.000
I00-I02 Acute rheumatic fever
0.716 0.284 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.715 0.284 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.715 0.284 0.000
I35.9 Aortic valve disorder, unspecified
0.715 0.285 0.000
D59 Acquired haemolytic anaemia
0.713 0.287 0.000
Z50 Care involving use of rehabilitation procedures
0.713 0.287 0.000
Q00-Q07 Congenital malformations of the nervous system
0.711 0.289 0.000
G44.0 Cluster headache syndrome
0.711 0.289 0.000
G04 Encephalitis, myelitis and encephalomyelitis
0.711 0.289 0.000
G91 Hydrocephalus
0.710 0.290 0.000
M54.28 Cervicalgia-Sacral/sacrococ
0.709 0.291 0.000
M54.27 Cervicalgia-Lumbosacral
0.709 0.291 0.000
M54.26 Cervicalgia-Lumbar
0.709 0.291 0.000
M54.25 Cervicalgia-Thoracolumbar
0.709 0.291 0.000
M54.24 Cervicalgia-Thoracic
0.709 0.291 0.000
M54.23 Cervicalgia (Cervicothoracic region)
0.709 0.291 0.000
M54.21 Cervicalgia (Occipito-atlanto-axial region)
0.709 0.291 0.000
M54.20 Cervicalgia-Mult site
0.709 0.291 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.709 0.291 0.000
Z22 Carrier of infectious disease
0.708 0.292 0.000
Z40 Prophylactic surgery
0.708 0.292 0.000
Z49 Care involving dialysis
0.708 0.292 0.000
Z45.0 Adjustment and management of cardiac pacemaker
0.708 0.292 0.000
G50 Disorders of trigeminal nerve
0.707 0.293 0.000
I35.1 Aortic (valve) insufficiency
0.707 0.293 0.000
I52 Other heart disorders in diseases classified elsewhere
0.707 0.293 0.000
I48 Atrial fibrillation and flutter
0.707 0.293 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.707 0.293 0.000
I41 Myocarditis in diseases classified elsewhere
0.707 0.293 0.000
I40 Acute myocarditis
0.707 0.293 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.707 0.293 0.000
I32 Pericarditis in diseases classified elsewhere
0.707 0.293 0.000
Z44 Fitting and adjustment of external prosthetic device
0.706 0.294 0.000
I44.0 Atrioventricular block, first degree
0.706 0.294 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.705 0.295 0.000
M51.3 Other specified intervertebral disk degeneration
0.705 0.295 0.000
M51.1 Lumbar and other intervertebral disk disorders with radiculopathy
0.705 0.295 0.000
M51.4 Schmorl's nodes
0.705 0.295 0.000
S61.7 Multiple open wounds of wrist and hand
0.702 0.298 0.000
T98 Sequelae of other and unspecified effects of external causes
0.702 0.298 0.000
T95 Sequelae of burns, corrosions and frostbite
0.702 0.298 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.702 0.298 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.702 0.298 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.702 0.298 0.000
M49 Spondylopathies in diseases classified elsewhere
0.702 0.298 0.000
W20 Struck by thrown, projected or falling object
0.702 0.298 0.000
I44.7 Left bundle-branch block, unspecified
0.702 0.298 0.000
S91 Open wound of ankle and foot
0.702 0.298 0.000
M00-M03 Infectious arthropathies
0.701 0.298 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.701 0.299 0.000
G58 Other mononeuropathies
0.701 0.299 0.000
I74 Arterial embolism and thrombosis
0.701 0.299 0.000
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)
0.700 0.300 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.700 0.300 0.000
S72 Fracture of femur
0.699 0.301 0.000
G06.0 Intracranial abscess and granuloma
0.699 0.301 0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)
0.698 0.302 0.000
S62 Fracture at wrist and hand level
0.696 0.304 0.000
M89.0 Algoneurodystrophy
0.696 0.304 0.000
I51.4 Myocarditis, unspecified
0.695 0.305 0.000
G45.8 Other transient cerebral ischaemic attacks and related syndromes
0.694 0.306 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.694 0.306 0.000
M48.5 Collapsed vertebra, not elsewhere classified
0.694 0.306 0.000
D53 Other nutritional anaemias
0.693 0.307 0.000
G30-G32 Other degenerative diseases of the nervous system
0.693 0.307 0.000
M54.57 Low back pain (Lumbosacral region)
0.691 0.309 0.000
S65 Injury of blood vessels at wrist and hand level
0.691 0.309 0.000
D50.1 Sideropenic dysphagia
0.691 0.309 0.000
Chapter I Certain infectious and parasitic diseases
0.691 0.309 0.000
M48.9 Spondylopathy, unspecified
0.690 0.310 0.000
M48.8 Other specified spondylopathies
0.690 0.310 0.000
M48.4 Fatigue fracture of vertebra
0.690 0.310 0.000
M48.3 Traumatic spondylopathy
0.690 0.310 0.000
M48.2 Kissing spine
0.690 0.310 0.000
M48.1 Ankylosing hyperostosis [Forestier]
0.690 0.310 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.690 0.310 0.000
S90 Superficial injury of ankle and foot
0.690 0.310 0.000
T78.1 Other adverse food reactions, not elsewhere classified
0.689 0.311 0.000
M19.98 Arthrosis, unspecified (Other)
0.688 0.312 0.000
I61.2 Intracerebral haemorrhage in hemisphere, unspecified
0.687 0.313 0.000
I60.8 Other subarachnoid haemorrhage
0.687 0.313 0.000
M19.09 Primary arthrosis of other joints (Site unspecified)
0.687 0.313 0.000
I49.1 Atrial premature depolarisation
0.686 0.313 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.686 0.314 0.000
M54.49 Lumbago with sciatica (Site unspecified)
0.686 0.314 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.686 0.314 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.686 0.314 0.000
Z50.8 Care involving use of rehabilitation procedures
0.686 0.314 0.000
Y35-Y36 Legal intervention and operations of war
0.685 0.315 0.000
Y10-Y34 Event of undetermined intent
0.685 0.315 0.000
X85-X99 Assault
0.685 0.315 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.685 0.315 0.000
X50-X57 Overexertion, travel and privation
0.685 0.315 0.000
X30-X39 Exposure to forces of nature
0.685 0.315 0.000
X20-X29 Contact with venomous animals and plants
0.685 0.315 0.000
X10-X19 Contact with heat and hot substances
0.685 0.315 0.000
X00-X09 Exposure to smoke, fire and flames
0.685 0.315 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.685 0.315 0.000
W75-W84 Other accidental threats to breathing
0.685 0.315 0.000
W65-W74 Accidental drowning and submersion
0.685 0.315 0.000
W50-W64 Exposure to animate mechanical forces
0.685 0.315 0.000
V98-V99 Other and unspecified transport accidents
0.685 0.315 0.000
V95-V97 Air and space transport accidents
0.685 0.315 0.000
V90-V94 Water transport accidents
0.685 0.315 0.000
V70-V79 Bus occupant injured in transport accident
0.685 0.315 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.685 0.315 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.685 0.315 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.685 0.315 0.000
V01-V09 Pedestrian injured in transport accident
0.685 0.315 0.000
H71 Cholesteatoma of middle ear
0.685 0.315 0.000
D52 Folate deficiency anaemia
0.684 0.316 0.000
M15 Polyarthrosis
0.683 0.317 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.683 0.317 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.682 0.318 0.000
Q35-Q37 Cleft lip and cleft palate
0.682 0.318 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.682 0.318 0.000
M48.08 Spinal stenosis (Sacral and sacrococcygeal region)
0.682 0.318 0.000
M48.05 Spinal stenosis (Thoracolumbar region)
0.682 0.318 0.000
M48.04 Spinal stenosis (Thoracic region)
0.682 0.318 0.000
M48.03 Spinal stenosis (Cervicothoracic region)
0.682 0.318 0.000
M48.01 Spinal stenosis (Occipito-atlanto-axial region)
0.682 0.318 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.681 0.319 0.000
I36 Nonrheumatic tricuspid valve disorders
0.680 0.320 0.000
M54.19 Radiculopathy (Site unspecified)
0.680 0.320 0.000
S69 Other and unspecified injuries of wrist and hand
0.679 0.321 0.000
I69.1 Sequelae of intracerebral haemorrhage
0.679 0.321 0.000
I62.0 Subdural haemorrhage (acute) (nontraumatic)
0.679 0.321 0.000
M54.18 Radiculopathy (Sacral and sacrococcygeal region)
0.678 0.321 0.000
M54.15 Radiculopathy (Thoracolumbar region)
0.678 0.321 0.000
M54.14 Radiculopathy (Thoracic region)
0.678 0.321 0.000
M54.13 Radiculopathy (Cervicothoracic region)
0.678 0.321 0.000
M54.11 Radiculopathy (Occipito-atlanto-axial region)
0.678 0.321 0.000
M54.10 Radiculopathy (Multiple sites in spine)
0.678 0.321 0.000
T92.0 Sequelae of open wound of upper limb
0.678 0.322 0.000
D60-D64 Aplastic and other anaemias
0.677 0.323 0.000
S50.9 Superficial injury of forearm, unspecified
0.677 0.323 0.000
I51.6 Cardiovascular disease, unspecified
0.676 0.324 0.000
I51.5 Myocardial degeneration
0.676 0.324 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.676 0.324 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.676 0.324 0.000
M54.48 Lumbago with sciatica (Sacral and sacrococcygeal region)
0.676 0.324 0.000
M54.45 Lumbago with sciatica (Thoracolumbar region)
0.676 0.324 0.000
M54.44 Lumbago with sciatica-Thoracic
0.676 0.324 0.000
M54.43 Lumbago with sciatica-Cervicothoracic
0.676 0.324 0.000
M54.42 Lumbago with sciatica-Cervical
0.676 0.324 0.000
M54.41 Lumbago with sciatica-Occipit-atl-axl
0.676 0.324 0.000
M54.40 Lumbago with sciatica (Multiple sites in spine)
0.676 0.324 0.000
G83 Other paralytic syndromes
0.676 0.324 0.000
S82.20 Fracture of shaft of tibia (closed)
0.675 0.325 0.000
T92.6 Sequelae of crushing injury and traumatic amputation of upper limb
0.675 0.325 0.000
T92.4 Sequelae of injury of nerve of upper limb
0.675 0.325 0.000
H74 Other disorders of middle ear and mastoid
0.675 0.325 0.000
T92.8 Sequelae of other specified injuries of upper limb
0.675 0.325 0.000
Z43.3 Attention to colostomy
0.675 0.325 0.000
G93 Other disorders of brain
0.674 0.326 0.000
Y40.9 Systemic antibiotic, unspecified
0.673 0.327 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.673 0.327 0.000
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.673 0.327 0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.673 0.327 0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.673 0.327 0.000
S52 Fracture of forearm
0.673 0.327 0.000
M54.3 Sciatica
0.672 0.327 0.000
G54 Nerve root and plexus disorders
0.672 0.328 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.672 0.328 0.000
G40.9 Epilepsy, unspecified
0.672 0.328 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.671 0.329 0.000
X60-X84 Intentional self-harm
0.670 0.330 0.000
Y59 Other and unspecified vaccines and biological substances
0.670 0.330 0.000
Y58 Bacterial vaccines
0.670 0.330 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.670 0.330 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.670 0.330 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.670 0.330 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.670 0.330 0.000
Y48 Anaesthetics and therapeutic gases
0.670 0.330 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.670 0.330 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.670 0.330 0.000
G08 Intracranial and intraspinal phlebitis and thrombophlebitis
0.670 0.330 0.000
I34 Nonrheumatic mitral valve disorders
0.670 0.330 0.000
T75 Effects of other external causes
0.669 0.330 0.000
T74 Maltreatment syndromes
0.669 0.330 0.000
T73 Effects of other deprivation
0.669 0.330 0.000
T70 Effects of air pressure and water pressure
0.669 0.330 0.000
T69 Other effects of reduced temperature
0.669 0.330 0.000
T67 Effects of heat and light
0.669 0.330 0.000
T71 Asphyxiation
0.669 0.330 0.000
T66 Unspecified effects of radiation
0.669 0.330 0.000
M54.47 Lumbago with sciatica (Lumbosacral region)
0.669 0.331 0.000
M19.8 Other specified arthrosis
0.667 0.333 0.000
M19.2 Other secondary arthrosis
0.667 0.333 0.000
T91.8 Sequelae of other specified injuries of neck and trunk
0.666 0.334 0.000
M86.6 Other chronic osteomyelitis
0.666 0.334 0.000
M80 Osteoporosis with pathological fracture
0.665 0.334 0.000
I51.0 Cardiac septal defect, acquired
0.664 0.336 0.000
W49 Exposure to other and unspecified inanimate mechanical forces
0.664 0.336 0.000
I46 Cardiac arrest
0.663 0.336 0.000
Z22.3 Carrier of other specified bacterial diseases
0.663 0.337 0.000
G45.3 Amaurosis fugax
0.663 0.337 0.000
Z56 Problems related to employment and unemployment
0.662 0.338 0.000
M53 Other dorsopathies, not elsewhere classified
0.661 0.338 0.000
Y40.0 Penicillins
0.661 0.339 0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.661 0.339 0.000
I60.1 Subarachnoid haemorrhage from middle cerebral artery
0.660 0.339 0.000
G45.2 Multiple and bilateral precerebral artery syndromes
0.660 0.340 0.000
G45.1 Carotid artery syndrome (hemispheric)
0.660 0.340 0.000
G45.0 Vertebro-basilar artery syndrome
0.660 0.340 0.000
S79 Other and unspecified injuries of hip and thigh
0.660 0.340 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.660 0.340 0.000
I08 Multiple valve diseases
0.659 0.341 0.000
S12.10 Fracture of second cervical vertebra (closed)
0.658 0.342 0.000
I49.8 Other specified cardiac arrhythmias
0.657 0.343 0.000
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified
0.657 0.343 0.000
I60.6 Subarachnoid haemorrhage from other intracranial arteries
0.657 0.343 0.000
I60.5 Subarachnoid haemorrhage from vertebral artery
0.657 0.343 0.000
I60.4 Subarachnoid haemorrhage from basilar artery
0.657 0.343 0.000
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation
0.657 0.343 0.000
Y41.8 Other specified systemic anti-infectives and antiparasitics
0.657 0.343 0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.656 0.344 0.000
Z29 Need for other prophylactic measures
0.656 0.344 0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level
0.656 0.344 0.000
M50.2 Other cervical disk displacement
0.656 0.344 0.000
G52 Disorders of other cranial nerves
0.656 0.344 0.000
M75 Shoulder lesions
0.656 0.344 0.000
H60-H62 Diseases of external ear
0.656 0.344 0.000
S17 Crushing injury of neck
0.656 0.344 0.000
S15 Injury of blood vessels at neck level
0.656 0.344 0.000
S14 Injury of nerves and spinal cord at neck level
0.656 0.344 0.000
S11 Open wound of neck
0.656 0.344 0.000
S18 Traumatic amputation at neck level
0.656 0.344 0.000
S16 Injury of muscle and tendon at neck level
0.656 0.344 0.000
G95.9 Disease of spinal cord, unspecified
0.654 0.346 0.000
Q51.3 Bicornate uterus
0.654 0.346 0.000
S68 Traumatic amputation of wrist and hand
0.654 0.346 0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments
0.653 0.347 0.000
S19.9 Unspecified injury of neck
0.653 0.347 0.000
G80 Infantile cerebral palsy
0.653 0.347 0.000
M50.0 Cervical disk disorder with myelopathy
0.653 0.347 0.000
H65.3 Chronic mucoid otitis media
0.653 0.347 0.000
I77 Other disorders of arteries and arterioles
0.652 0.348 0.000
Y40.3 Macrolides
0.651 0.349 0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.651 0.349 0.000
M77 Other enthesopathies
0.651 0.349 0.000
H73 Other disorders of tympanic membrane
0.651 0.349 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.651 0.349 0.000
Y57 Other and unspecified drugs and medicaments
0.650 0.349 0.000
M50.9 Cervical disk disorder, unspecified
0.649 0.350 0.000
M50.8 Other cervical disk disorders
0.649 0.350 0.000
Q54 Hypospadias
0.649 0.351 0.000
M75.4 Impingement syndrome of shoulder
0.649 0.351 0.000
I61.5 Intracerebral haemorrhage, intraventricular
0.649 0.351 0.000
S92 Fracture of foot, except ankle
0.649 0.351 0.000
M19.96 Arthrosis, unspecified-Lower leg
0.649 0.351 0.000
H69 Other disorders of Eustachian tube
0.649 0.351 0.000
S59 Other and unspecified injuries of forearm
0.648 0.352 0.000
M18.0 Primary arthrosis of first carpometacarpal joints, bilateral
0.646 0.354 0.000
T91.1 Sequelae of fracture of spine
0.645 0.355 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.645 0.355 0.000
Y43.0 Antiallergic and antiemetic drugs
0.644 0.356 0.000
Q61.2 Polycystic kidney, adult type
0.644 0.356 0.000
G70-G73 Diseases of myoneural junction and muscle
0.644 0.356 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.643 0.357 0.000
I37.1 Pulmonary valve insufficiency
0.643 0.357 0.000
S10 Superficial injury of neck
0.641 0.359 0.000
V80-V89 Other land transport accidents
0.641 0.359 0.000
Z63 Other problems related to primary support group, including family circumstances
0.641 0.359 0.000
I61.8 Other intracerebral haemorrhage
0.640 0.359 0.000
I61.6 Intracerebral haemorrhage, multiple localised
0.640 0.359 0.000
I61.4 Intracerebral haemorrhage in cerebellum
0.640 0.359 0.000
I61.3 Intracerebral haemorrhage in brain stem
0.640 0.359 0.000
I61.1 Intracerebral haemorrhage in hemisphere, cortical
0.640 0.359 0.000
I61.0 Intracerebral haemorrhage in hemisphere, subcortical
0.640 0.359 0.000
M88 Paget's disease of bone [osteitis deformans]
0.640 0.360 0.000
V20-V29 Motorcycle rider injured in transport accident
0.640 0.360 0.000
S12.2 Fracture of other specified cervical vertebra
0.639 0.361 0.000
M19.08 Primary arthrosis of other joints (Other)
0.638 0.362 0.000
M19.06 Primary arthrosis of other joints-Lower leg
0.638 0.362 0.000
M19.05 Primary arthrosis of other joints (Pelvic region and thigh)
0.638 0.362 0.000
M19.00 Primary arthrosis of other joints (Multiple sites)
0.638 0.362 0.000
W46 Contact with hypodermic needle
0.638 0.362 0.000
W45 Foreign body or object entering through skin
0.638 0.362 0.000
W43 Exposure to vibration
0.638 0.362 0.000
W42 Exposure to noise
0.638 0.362 0.000
W41 Exposure to high-pressure jet
0.638 0.362 0.000
W40 Explosion of other materials
0.638 0.362 0.000
W39 Discharge of firework
0.638 0.362 0.000
W38 Explosion and rupture of other specified pressurised devices
0.638 0.362 0.000
W37 Explosion and rupture of pressurised tyre, pipe or hose
0.638 0.362 0.000
W36 Explosion and rupture of gas cylinder
0.638 0.362 0.000
W35 Explosion and rupture of boiler
0.638 0.362 0.000
W34 Discharge from other and unspecified firearms
0.638 0.362 0.000
W33 Rifle, shotgun and larger firearm discharge
0.638 0.362 0.000
W32 Handgun discharge
0.638 0.362 0.000
W31 Contact with other and unspecified machinery
0.638 0.362 0.000
W30 Contact with agricultural machinery
0.638 0.362 0.000
W28 Contact with powered lawn mower
0.638 0.362 0.000
W27 Contact with nonpowered hand tool
0.638 0.362 0.000
W26 Contact with knife, sword or dagger
0.638 0.362 0.000
W24 Contact with lifting and transmission devices, not elsewhere classified
0.638 0.362 0.000
W23 Caught, crushed, jammed or pinched in or between objects
0.638 0.362 0.000
W21 Striking against or struck by sports equipment
0.638 0.362 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.637 0.363 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.637 0.363 0.000
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere
0.636 0.364 0.000
G02 Meningitis in other infectious and parasitic diseases classified elsewhere
0.636 0.364 0.000
G00 Bacterial meningitis, not elsewhere classified
0.636 0.364 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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