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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs117297586
log Bayes Factor = 6.19757
Chromosome 8   position 50,205,976  (GRCh37) Explore rs117297586 on Ensembl!
Variant rs117297586 is part of Cluster X0117

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
J40-J47 Chronic lower respiratory diseases
1.000 0.000 0.000
Chapter X Diseases of the respiratory system
1.000 0.000 0.000
J44 Other chronic obstructive pulmonary disease
1.000 0.000 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.999 0.001 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.997 0.003 0.000
M20-M25 Other joint disorders
0.997 0.003 0.000
J90-J94 Other diseases of pleura
0.997 0.003 0.000
J93 Pneumothorax
0.995 0.005 0.000
# Top node
0.995 0.005 0.000
J93.9 Pneumothorax, unspecified
0.992 0.008 0.000
M20 Acquired deformities of fingers and toes
0.991 0.009 0.000
J95-J99 Other diseases of the respiratory system
0.991 0.009 0.000
M25 Other joint disorders, not elsewhere classified
0.986 0.014 0.000
Chapter II Neoplasms
0.981 0.019 0.000
Chapter XX External causes of morbidity and mortality
0.981 0.019 0.000
M20.5 Other deformities of toe(s) (acquired)
0.979 0.021 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.974 0.026 0.000
J98 Other respiratory disorders
0.972 0.028 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.972 0.028 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.970 0.030 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.968 0.032 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.964 0.036 0.000
C34 Malignant neoplasm of bronchus and lung
0.958 0.042 0.000
J43 Emphysema
0.955 0.045 0.000
J47 Bronchiectasis
0.945 0.055 0.000
M20.4 Other hammer toe(s) (acquired)
0.943 0.057 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.939 0.061 0.000
M25.8 Other specified joint disorders
0.935 0.065 0.000
M70-M79 Other soft tissue disorders
0.929 0.071 0.000
J43.9 Emphysema, unspecified
0.922 0.078 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.919 0.081 0.000
C79 Secondary malignant neoplasm of other sites
0.913 0.087 0.000
M31 Other necrotising vasculopathies
0.912 0.088 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.911 0.089 0.000
Y52 Agents primarily affecting the cardiovascular system
0.911 0.089 0.000
J92 Pleural plaque
0.908 0.092 0.000
M25.5 Pain in joint
0.907 0.093 0.000
M79.8 Other specified soft tissue disorders
0.906 0.094 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.906 0.094 0.000
C34.1 Upper lobe, bronchus or lung
0.903 0.097 0.000
M20.6 Acquired deformity of toe(s), unspecified
0.899 0.101 0.000
C80 Malignant neoplasm without specification of site
0.899 0.101 0.000
Y86 Sequelae of other accidents
0.896 0.104 0.000
J98.0 Diseases of bronchus, not elsewhere classified
0.893 0.107 0.000
Q80-Q89 Other congenital malformations
0.889 0.111 0.000
M80-M85 Disorders of bone density and structure
0.889 0.111 0.000
M79.86 Other specified soft tissue disorders (Lower leg)
0.887 0.113 0.000
M21 Other acquired deformities of limbs
0.886 0.114 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.884 0.116 0.000
C34.3 Lower lobe, bronchus or lung
0.874 0.126 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.868 0.132 0.000
J46 Status asthmaticus
0.868 0.132 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.866 0.134 0.000
M05-M14 Inflammatory polyarthropathies
0.866 0.134 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.865 0.135 0.000
J92.0 Pleural plaque with presence of asbestos
0.862 0.138 0.000
C34.9 Bronchus or lung, unspecified
0.860 0.140 0.000
M00-M03 Infectious arthropathies
0.859 0.141 0.000
M25.87 Other specified joint disorders (Ankle and foot)
0.854 0.146 0.000
J93.1 Other spontaneous pneumothorax
0.854 0.146 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.842 0.158 0.000
M25.56 Pain in joint (Lower leg)
0.836 0.164 0.000
M25.50 Pain in joint (Multiple sites)
0.834 0.166 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.832 0.168 0.000
M79.6 Pain in limb
0.832 0.168 0.000
M10 Gout
0.831 0.169 0.000
M86-M90 Other osteopathies
0.827 0.173 0.000
J98.8 Other specified respiratory disorders
0.827 0.173 0.000
Q21 Congenital malformations of cardiac septa
0.825 0.175 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.823 0.177 0.000
M25.85 Other specified joint disorders (Pelvic region and thigh)
0.818 0.182 0.000
C78.7 Secondary malignant neoplasm of liver
0.818 0.182 0.000
M40-M43 Deforming dorsopathies
0.818 0.182 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.817 0.182 0.000
M25.7 Osteophyte
0.812 0.188 0.000
Q82 Other congenital malformations of skin
0.810 0.190 0.000
J98.5 Diseases of mediastinum, not elsewhere classified
0.810 0.190 0.000
M25.53 Pain in joint (Forearm)
0.808 0.192 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.808 0.192 0.000
J93.8 Other pneumothorax
0.807 0.193 0.000
M10.9 Gout, unspecified
0.807 0.193 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.805 0.195 0.000
J42 Unspecified chronic bronchitis
0.802 0.197 0.000
C91 Lymphoid leukaemia
0.802 0.198 0.000
M80 Osteoporosis with pathological fracture
0.799 0.201 0.000
C80.9 Malignant neoplasm, unspecified
0.798 0.202 0.000
C15-C26 Malignant neoplasms of digestive organs
0.797 0.203 0.000
J98.9 Respiratory disorder, unspecified
0.796 0.204 0.000
M25.84 Other specified joint disorders (Hand)
0.796 0.204 0.000
Chapter I Certain infectious and parasitic diseases
0.793 0.207 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.791 0.209 0.000
C37 Malignant neoplasm of thymus
0.790 0.209 0.000
Chapter XXII Codes for special purposes
0.786 0.214 0.000
J95.8 Other postprocedural respiratory disorders
0.786 0.214 0.000
M31.6 Other giant cell arteritis
0.784 0.216 0.000
C90.0 Multiple myeloma
0.781 0.218 0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified
0.777 0.223 0.000
Q27 Other congenital malformations of peripheral vascular system
0.776 0.224 0.000
M31.3 Wegener's granulomatosis
0.775 0.225 0.000
M60-M63 Disorders of muscles
0.774 0.226 0.000
C90.2 Plasmacytoma, extramedullary
0.766 0.234 0.000
Y45.5 4-Aminophenol derivatives
0.766 0.234 0.000
C80.0 Malignant neoplasm, primary site unknown, so stated
0.764 0.236 0.000
X20-X29 Contact with venomous animals and plants
0.763 0.237 0.000
J98.6 Disorders of diaphragm
0.762 0.238 0.000
M00 Pyogenic arthritis
0.761 0.239 0.000
M21.0 Valgus deformity, not elsewhere classified
0.760 0.240 0.000
J94 Other pleural conditions
0.760 0.240 0.000
M79.65 Pain in limb (Pelvic region and thigh)
0.760 0.240 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.759 0.241 0.000
Y88 Sequelae of surgical and medical care as external cause
0.758 0.242 0.000
M79.84 Other specified soft tissue disorders (Hand)
0.758 0.242 0.000
M25.3 Other instability of joint
0.756 0.244 0.000
M10.97 Gout, unspecified (Ankle and foot)
0.755 0.245 0.000
M84 Disorders of continuity of bone
0.754 0.246 0.000
M79.83 Other specified soft tissue disorders (Forearm)
0.754 0.246 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.753 0.247 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.753 0.247 0.000
J99 Respiratory disorders in diseases classified elsewhere
0.752 0.247 0.000
M21.3 Wrist or foot drop (acquired)
0.752 0.248 0.000
J20-J22 Other acute lower respiratory infections
0.751 0.249 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.751 0.249 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.749 0.251 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.747 0.253 0.000
B35-B49 Mycoses
0.746 0.254 0.000
Y00-Y09 Assault
0.742 0.258 0.000
Q21.1 Atrial septal defect
0.742 0.258 0.000
M25.4 Effusion of joint
0.738 0.262 0.000
Q24 Other congenital malformations of heart
0.737 0.263 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.736 0.264 0.000
J98.4 Other disorders of lung
0.736 0.264 0.000
W20-W49 Exposure to inanimate mechanical forces
0.734 0.266 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.733 0.267 0.000
C88 Malignant immunoproliferative diseases
0.733 0.267 0.000
C79.2 Secondary malignant neoplasm of skin
0.733 0.267 0.000
M65-M68 Disorders of synovium and tendon
0.733 0.267 0.000
X60-X84 Intentional self-harm
0.732 0.268 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.732 0.268 0.000
W50-W64 Exposure to animate mechanical forces
0.731 0.269 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.730 0.270 0.000
Y52.3 Coronary vasodilators, not elsewhere classified
0.730 0.270 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.729 0.271 0.000
M25.57 Pain in joint (Ankle and foot)
0.727 0.273 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.726 0.274 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.725 0.275 0.000
M35 Other systemic involvement of connective tissue
0.724 0.276 0.000
V40-V49 Car occupant injured in transport accident
0.723 0.277 0.000
Y89 Sequelae of other external causes
0.721 0.278 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.721 0.278 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.718 0.282 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.718 0.282 0.000
M25.71 Osteophyte (Shoulder region)
0.717 0.283 0.000
J41 Simple and mucopurulent chronic bronchitis
0.717 0.283 0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified
0.716 0.284 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.716 0.284 0.000
B37 Candidiasis
0.715 0.285 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.715 0.285 0.000
M33 Dermatopolymyositis
0.715 0.285 0.000
M32 Systemic lupus erythematosus
0.715 0.285 0.000
M30 Polyarteritis nodosa and related conditions
0.715 0.285 0.000
J93.0 Spontaneous tension pneumothorax
0.714 0.286 0.000
X50-X57 Overexertion, travel and privation
0.713 0.287 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.713 0.287 0.000
X10-X19 Contact with heat and hot substances
0.712 0.288 0.000
C32 Malignant neoplasm of larynx
0.712 0.288 0.000
M41 Scoliosis
0.711 0.289 0.000
J96 Respiratory failure, not elsewhere classified
0.710 0.290 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.709 0.290 0.000
M80.9 Unspecified osteoporosis with pathological fracture
0.709 0.291 0.000
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.709 0.291 0.000
Y45.0 Opioids and related analgesics
0.709 0.291 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.708 0.292 0.000
Y45.8 Other analgesics and antipyretics
0.708 0.292 0.000
Q50-Q56 Congenital malformations of genital organs
0.707 0.293 0.000
M25.2 Flail joint
0.707 0.293 0.000
M25.1 Fistula of joint
0.707 0.293 0.000
C49 Malignant neoplasm of other connective and soft tissue
0.706 0.294 0.000
C23 Malignant neoplasm of gallbladder
0.704 0.296 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.703 0.297 0.000
Y35-Y36 Legal intervention and operations of war
0.703 0.297 0.000
Y10-Y34 Event of undetermined intent
0.703 0.297 0.000
X85-X99 Assault
0.703 0.297 0.000
X30-X39 Exposure to forces of nature
0.703 0.297 0.000
X00-X09 Exposure to smoke, fire and flames
0.703 0.297 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.703 0.297 0.000
W75-W84 Other accidental threats to breathing
0.703 0.297 0.000
W65-W74 Accidental drowning and submersion
0.703 0.297 0.000
V98-V99 Other and unspecified transport accidents
0.703 0.297 0.000
V95-V97 Air and space transport accidents
0.703 0.297 0.000
V90-V94 Water transport accidents
0.703 0.297 0.000
V70-V79 Bus occupant injured in transport accident
0.703 0.297 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.703 0.297 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.703 0.297 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.703 0.297 0.000
V01-V09 Pedestrian injured in transport accident
0.703 0.297 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.703 0.297 0.000
M20.0 Deformity of finger(s)
0.701 0.299 0.000
M20.3 Other deformity of hallux (acquired)
0.701 0.299 0.000
Y52.1 Calcium-channel blockers
0.701 0.299 0.000
M25.77 Osteophyte (Ankle and foot)
0.700 0.300 0.000
J98.3 Compensatory emphysema
0.697 0.303 0.000
J98.2 Interstitial emphysema
0.697 0.303 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.697 0.303 0.000
Q35-Q37 Cleft lip and cleft palate
0.697 0.303 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.697 0.303 0.000
M21.2 Flexion deformity
0.696 0.304 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.696 0.304 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.696 0.304 0.000
C31 Malignant neoplasm of accessory sinuses
0.696 0.304 0.000
C30 Malignant neoplasm of nasal cavity and middle ear
0.696 0.304 0.000
C33 Malignant neoplasm of trachea
0.696 0.304 0.000
M71 Other bursopathies
0.694 0.305 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.694 0.306 0.000
M25.9 Joint disorder, unspecified
0.694 0.306 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.694 0.306 0.000
M25.52 Pain in joint (Upper arm)
0.693 0.307 0.000
Y52.4 Angiotensin-converting-enzyme inhibitors
0.692 0.308 0.000
Y59 Other and unspecified vaccines and biological substances
0.691 0.309 0.000
Y58 Bacterial vaccines
0.691 0.309 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.691 0.309 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.691 0.309 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.691 0.309 0.000
Y48 Anaesthetics and therapeutic gases
0.691 0.309 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.691 0.309 0.000
M79.80 Other specified soft tissue disorders (Multiple sites)
0.691 0.309 0.000
M00.9 Pyogenic arthritis, unspecified
0.690 0.310 0.000
M21.06 Valgus deformity, not elsewhere classified (Lower leg)
0.690 0.310 0.000
J09-J18 Influenza and pneumonia
0.690 0.310 0.000
J43.2 Centrilobular emphysema
0.689 0.311 0.000
M89 Other disorders of bone
0.689 0.311 0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.687 0.313 0.000
C34.8 Overlapping lesion of bronchus and lung
0.687 0.313 0.000
J86 Pyothorax
0.687 0.313 0.000
Y57 Other and unspecified drugs and medicaments
0.686 0.314 0.000
Q12 Congenital lens malformations
0.686 0.314 0.000
J43.8 Other emphysema
0.684 0.315 0.000
J43.1 Panlobular emphysema
0.684 0.315 0.000
J43.0 MacLeod's syndrome
0.684 0.315 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.683 0.317 0.000
Q82.5 Congenital nonneoplastic naevus
0.682 0.318 0.000
M14 Arthropathies in other diseases classified elsewhere
0.681 0.318 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.681 0.319 0.000
M79.2 Neuralgia and neuritis, unspecified
0.681 0.319 0.000
M79.9 Soft tissue disorder, unspecified
0.680 0.319 0.000
C34.2 Middle lobe, bronchus or lung
0.680 0.320 0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica
0.679 0.321 0.000
Q89 Other congenital malformations, not elsewhere classified
0.679 0.321 0.000
Q82.2 Mastocytosis
0.679 0.321 0.000
Q85 Phakomatoses, not elsewhere classified
0.678 0.322 0.000
C25 Malignant neoplasm of pancreas
0.678 0.322 0.000
C91.5 Adult T-cell leukaemia
0.677 0.323 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.675 0.325 0.000
M21.4 Flat foot [pes planus] (acquired)
0.674 0.325 0.000
M79.87 Other specified soft tissue disorders (Ankle and foot)
0.674 0.326 0.000
C50-C50 Malignant neoplasm of breast
0.674 0.326 0.000
M10.99 Gout, unspecified (Site unspecified)
0.673 0.327 0.000
Q27.8 Other specified congenital malformations of peripheral vascular system
0.673 0.327 0.000
Y87 Sequelae of intentional self-harm, assault and events of undetermined intent
0.673 0.327 0.000
M72 Fibroblastic disorders
0.672 0.327 0.000
M79.63 Pain in limb (Forearm)
0.672 0.328 0.000
B99-B99 Other infectious diseases
0.672 0.328 0.000
M25.89 Other specified joint disorders (Site unspecified)
0.670 0.330 0.000
M25.88 Other specified joint disorders (Other)
0.670 0.330 0.000
M25.83 Other specified joint disorders (Forearm)
0.670 0.330 0.000
M25.82 Other specified joint disorders (Upper arm)
0.670 0.330 0.000
M25.81 Other specified joint disorders (Shoulder region)
0.670 0.330 0.000
M25.80 Other specified joint disorders (Multiple sites)
0.670 0.330 0.000
M86 Osteomyelitis
0.669 0.331 0.000
M79.7 Fibromyalgia
0.669 0.331 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.668 0.332 0.000
M76 Enthesopathies of lower limb, excluding foot
0.666 0.334 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.666 0.334 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.666 0.334 0.000
Q21.0 Ventricular septal defect
0.665 0.335 0.000
M79.64 Pain in limb (Hand)
0.664 0.336 0.000
M79.68 Pain in limb (Other)
0.663 0.337 0.000
C22.1 Intrahepatic bile duct carcinoma
0.662 0.338 0.000
V80-V89 Other land transport accidents
0.660 0.340 0.000
M79.3 Panniculitis, unspecified
0.659 0.341 0.000
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)
0.657 0.343 0.000
M25.0 Haemarthrosis
0.657 0.343 0.000
M21.37 Wrist or foot drop (acquired) (Ankle and foot)
0.656 0.344 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.655 0.345 0.000
C78.2 Secondary malignant neoplasm of pleura
0.654 0.346 0.000
M31.9 Necrotising vasculopathy, unspecified
0.654 0.346 0.000
M31.8 Other specified necrotising vasculopathies
0.654 0.346 0.000
M31.7 Microscopic polyangiitis
0.654 0.346 0.000
M31.4 Aortic arch syndrome [Takayasu]
0.654 0.346 0.000
M31.2 Lethal midline granuloma
0.654 0.346 0.000
M31.1 Thrombotic microangiopathy
0.654 0.346 0.000
M31.0 Hypersensitivity angiitis
0.654 0.346 0.000
M25.72 Osteophyte (Upper arm)
0.653 0.347 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.653 0.347 0.000
C95 Leukaemia of unspecified cell type
0.653 0.347 0.000
C94 Other leukaemias of specified cell type
0.653 0.347 0.000
C93 Monocytic leukaemia
0.653 0.347 0.000
C86 Other specified types of T/NK-cell lymphoma
0.653 0.347 0.000
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system
0.653 0.347 0.000
Y52.8 Antivaricose drugs, including sclerosing agents
0.653 0.347 0.000
Y52.7 Peripheral vasodilators
0.653 0.347 0.000
Y52.0 Cardiac-stimulant glycosides and drugs of similar action
0.653 0.347 0.000
M25.58 Pain in joint (Other)
0.650 0.350 0.000
C22.0 Liver cell carcinoma
0.650 0.350 0.000
J60-J70 Lung diseases due to external agents
0.650 0.350 0.000
M79.88 Other specified soft tissue disorders (Other)
0.649 0.350 0.000
M79.81 Other specified soft tissue disorders (Shoulder region)
0.649 0.350 0.000
Q26 Congenital malformations of great veins
0.649 0.351 0.000
Q25 Congenital malformations of great arteries
0.649 0.351 0.000
Q22 Congenital malformations of pulmonary and tricuspid valves
0.649 0.351 0.000
Q20 Congenital malformations of cardiac chambers and connexions
0.649 0.351 0.000
C91.9 Lymphoid leukaemia, unspecified
0.649 0.351 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.649 0.351 0.000
M10.96 Gout, unspecified (Lower leg)
0.648 0.352 0.000
B37.3 Candidiasis of vulva and vagina
0.647 0.353 0.000
B37.0 Candidal stomatitis
0.647 0.353 0.000
M79.67 Pain in limb (Ankle and foot)
0.647 0.353 0.000
Q00-Q07 Congenital malformations of the nervous system
0.644 0.356 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.642 0.358 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.642 0.358 0.000
J84 Other interstitial pulmonary diseases
0.641 0.359 0.000
M80.0 Postmenopausal osteoporosis with pathological fracture
0.640 0.360 0.000
Y44 Agents primarily affecting blood constituents
0.640 0.360 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.640 0.360 0.000
M91-M94 Chondropathies
0.638 0.362 0.000
Q86 Congenital malformation syndromes due to known exogenous causes, not elsewhere classified
0.638 0.362 0.000
Q84 Other congenital malformations of integument
0.638 0.362 0.000
Q83 Congenital malformations of breast
0.638 0.362 0.000
Q81 Epidermolysis bullosa
0.638 0.362 0.000
Q80 Congenital ichthyosis
0.638 0.362 0.000
M83 Adult osteomalacia
0.637 0.362 0.000
M82 Osteoporosis in diseases classified elsewhere
0.637 0.362 0.000
M21.9 Acquired deformity of limb, unspecified
0.635 0.365 0.000
M21.8 Other specified acquired deformities of limbs
0.635 0.365 0.000
M21.7 Unequal limb length (acquired)
0.635 0.365 0.000
M41.9 Scoliosis, unspecified
0.634 0.366 0.000
Q82.8 Other specified congenital malformations of skin
0.634 0.366 0.000
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified
0.634 0.366 0.000
Y45.4 Antirheumatics
0.634 0.366 0.000
Y45.2 Propionic acid derivatives
0.634 0.366 0.000
Y46.4 Iminostilbenes
0.633 0.366 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.631 0.369 0.000
B65-B83 Helminthiases
0.631 0.369 0.000
C77.1 Intrathoracic lymph nodes
0.630 0.370 0.000
J98.1 Pulmonary collapse
0.630 0.370 0.000
Y88.3 Sequelae of surgical and medical procedures as the cause of abnormal reaction of the patient or of later complication, without mention of misadventure at the time of the procedure
0.629 0.371 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.629 0.371 0.000
Y42.7 Androgens and anabolic congeners
0.627 0.373 0.000
J95.9 Postprocedural respiratory disorder, unspecified
0.622 0.378 0.000
J95.5 Postprocedural subglottic stenosis
0.622 0.378 0.000
J95.4 Mendelson's syndrome
0.622 0.378 0.000
J95.3 Chronic pulmonary insufficiency following surgery
0.622 0.378 0.000
J95.2 Acute pulmonary insufficiency following nonthoracic surgery
0.622 0.378 0.000
J95.1 Acute pulmonary insufficiency following thoracic surgery
0.622 0.378 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.621 0.379 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.621 0.379 0.000
M12 Other specific arthropathies
0.621 0.379 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.621 0.379 0.000
M08 Juvenile arthritis
0.621 0.379 0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.621 0.379 0.000
C90.3 Solitary plasmacytoma
0.620 0.380 0.000
C90.1 Plasma cell leukaemia
0.620 0.380 0.000
C77.0 Lymph nodes of head, face and neck
0.619 0.381 0.000
Q87 Other specified congenital malformation syndromes affecting multiple systems
0.618 0.382 0.000
C48 Malignant neoplasm of retroperitoneum and peritoneum
0.617 0.383 0.000
Q24.8 Other specified congenital malformations of heart
0.617 0.383 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.616 0.383 0.000
M03 Postinfective and reactive arthropathies in diseases classified elsewhere
0.616 0.384 0.000
M02 Reactive arthropathies
0.616 0.384 0.000
M01 Direct infections of joint in infectious and parasitic diseases classified elsewhere
0.616 0.384 0.000
M79.85 Other specified soft tissue disorders (Pelvic region and thigh)
0.615 0.385 0.000
Y46.2 Hydantoin derivatives
0.615 0.385 0.000
C45 Mesothelioma
0.615 0.385 0.000
J20 Acute bronchitis
0.614 0.386 0.000
M79.61 Pain in limb (Shoulder region)
0.614 0.386 0.000
M10.90 Gout, unspecified (Multiple sites)
0.612 0.388 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.612 0.388 0.000
Y53.4 Other laxatives
0.612 0.388 0.000
M00.96 Pyogenic arthritis, unspecified (Lower leg)
0.610 0.390 0.000
M40 Kyphosis and lordosis
0.610 0.390 0.000
M25.36 Other instability of joint (Lower leg)
0.610 0.390 0.000
Y42.5 Other oestrogens and progestogens
0.608 0.391 0.000
C79.6 Secondary malignant neoplasm of ovary
0.608 0.392 0.000
M79.5 Residual foreign body in soft tissue
0.607 0.393 0.000
B50-B64 Protozoal diseases
0.607 0.393 0.000
X23 Contact with hornets, wasps and bees
0.607 0.393 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.607 0.393 0.000
C91.4 Hairy-cell leukaemia
0.605 0.395 0.000
C88.0 Waldenstrom's macroglobulinaemia
0.605 0.395 0.000
M81 Osteoporosis without pathological fracture
0.605 0.395 0.000
J95.0 Tracheostomy malfunction
0.605 0.395 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.604 0.396 0.000
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified
0.603 0.397 0.000
C22.9 Liver, unspecified
0.602 0.397 0.000
A00-A09 Intestinal infectious diseases
0.602 0.398 0.000
V20-V29 Motorcycle rider injured in transport accident
0.602 0.398 0.000
C49.1 Connective and soft tissue of upper limb, including shoulder
0.601 0.399 0.000
Q12.0 Congenital cataract
0.600 0.400 0.000
Q60-Q64 Congenital malformations of the urinary system
0.598 0.401 0.000
C47 Malignant neoplasm of peripheral nerves and autonomic nervous system
0.597 0.403 0.000
C46 Kaposi's sarcoma
0.597 0.403 0.000
M10.4 Other secondary gout
0.596 0.404 0.000
M10.3 Gout due to impairment of renal function
0.596 0.404 0.000
M10.2 Drug-induced gout
0.596 0.404 0.000
M10.1 Lead-induced gout
0.596 0.404 0.000
M10.0 Idiopathic gout
0.596 0.404 0.000
A80-A89 Viral infections of the central nervous system
0.595 0.405 0.000
Y85 Sequelae of transport accidents
0.595 0.405 0.000
C77.5 Intrapelvic lymph nodes
0.595 0.405 0.000
M79.66 Pain in limb (Lower leg)
0.594 0.406 0.000
M87 Osteonecrosis
0.593 0.407 0.000
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot
0.593 0.407 0.000
M60 Myositis
0.592 0.408 0.000
Q21.9 Congenital malformation of cardiac septum, unspecified
0.592 0.408 0.000
Q21.8 Other congenital malformations of cardiac septa
0.592 0.408 0.000
Q21.4 Aortopulmonary septal defect
0.592 0.408 0.000
Q21.3 Tetralogy of Fallot
0.592 0.408 0.000
Q21.2 Atrioventricular septal defect
0.592 0.408 0.000
M05 Seropositive rheumatoid arthritis
0.592 0.408 0.000
J94.8 Other specified pleural conditions
0.591 0.409 0.000
Q28 Other congenital malformations of circulatory system
0.591 0.409 0.000
B37.8 Candidiasis of other sites
0.591 0.409 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.590 0.410 0.000
C77.8 Lymph nodes of multiple regions
0.590 0.410 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.590 0.410 0.000
M79.82 Other specified soft tissue disorders (Upper arm)
0.589 0.410 0.000
J86.9 Pyothorax without fistula
0.588 0.412 0.000
Y42.8 Other and unspecified hormones and their synthetic substitutes
0.587 0.413 0.000
M42 Spinal osteochondrosis
0.587 0.413 0.000
J85 Abscess of lung and mediastinum
0.586 0.414 0.000
B99 Other and unspecified infectious diseases
0.586 0.414 0.000
M06 Other rheumatoid arthritis
0.585 0.415 0.000
W20 Struck by thrown, projected or falling object
0.584 0.416 0.000
S90-S99 Injuries to the ankle and foot
0.584 0.416 0.000
M25.47 Effusion of joint (Ankle and foot)
0.583 0.417 0.000
X58 Exposure to other specified factors
0.583 0.417 0.000
M10.94 Gout, unspecified (Hand)
0.583 0.417 0.000
M25.79 Osteophyte (Site unspecified)
0.582 0.417 0.000
M25.73 Osteophyte (Forearm)
0.582 0.417 0.000
M25.70 Osteophyte (Multiple sites)
0.582 0.417 0.000
M34 Systemic sclerosis
0.582 0.417 0.000
C25.9 Pancreas, unspecified
0.582 0.418 0.000
M25.42 Effusion of joint (Upper arm)
0.582 0.418 0.000
Q82.9 Congenital malformation of skin, unspecified
0.581 0.419 0.000
Q82.4 Ectodermal dysplasia (anhidrotic)
0.581 0.419 0.000
Q82.3 Incontinentia pigmenti
0.581 0.419 0.000
Q82.1 Xeroderma pigmentosum
0.581 0.419 0.000
Q82.0 Hereditary lymphoedema
0.581 0.419 0.000
M62 Other disorders of muscle
0.581 0.419 0.000
Y42.9 Other and unspecified hormone antagonists
0.579 0.421 0.000
Y42.4 Oral contraceptives
0.579 0.421 0.000
Y42.2 Antithyroid drugs
0.579 0.421 0.000
Y42.1 Thyroid hormones and substitutes
0.579 0.421 0.000
Y42.0 Glucocorticoids and synthetic analogs
0.579 0.421 0.000
M10.98 Gout, unspecified (Other)
0.578 0.421 0.000
M10.95 Gout, unspecified (Pelvic region and thigh)
0.578 0.421 0.000
M10.93 Gout, unspecified (Forearm)
0.578 0.421 0.000
M10.92 Gout, unspecified (Upper arm)
0.578 0.421 0.000
M10.91 Gout, unspecified (Shoulder region)
0.578 0.421 0.000
M84.4 Pathological fracture, not elsewhere classified
0.578 0.421 0.000
M41.99 Scoliosis, unspecified (Site unspecified)
0.578 0.422 0.000
Q18 Other congenital malformations of face and neck
0.577 0.422 0.000
Q17 Other congenital malformations of ear
0.577 0.422 0.000
Q16 Congenital malformations of ear causing impairment of hearing
0.577 0.422 0.000
Q15 Other congenital malformations of eye
0.577 0.422 0.000
Q14 Congenital malformations of posterior segment of eye
0.577 0.422 0.000
Q13 Congenital malformations of anterior segment of eye
0.577 0.422 0.000
Q11 Anophthalmos, microphthalmos and macrophthalmos
0.577 0.422 0.000
Q10 Congenital malformations of eyelid, lachrymal apparatus and orbit
0.577 0.422 0.000
Q27.3 Peripheral arteriovenous malformation
0.577 0.423 0.000
C17 Malignant neoplasm of small intestine
0.576 0.424 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.575 0.425 0.000
M25.76 Osteophyte (Lower leg)
0.575 0.425 0.000
C91.8 Mature B-cell leukaemia Burkitt-type
0.575 0.425 0.000
C91.7 Other lymphoid leukaemia
0.575 0.425 0.000
C91.6 Prolymphocytic leukaemia of T-cell type
0.575 0.425 0.000
C91.3 Prolymphocytic leukaemia
0.575 0.425 0.000
C91.2 Subacute lymphocytic leukaemia
0.575 0.425 0.000
C91.0 Acute lymphoblastic leukaemia
0.575 0.425 0.000
M35.0 Sicca syndrome [Sjogren]
0.574 0.426 0.000
M21.6 Other acquired deformities of ankle and foot
0.574 0.426 0.000
C51-C58 Malignant neoplasms of female genital organs
0.574 0.426 0.000
V10-V19 Pedal cyclist injured in transport accident
0.573 0.427 0.000
Y57.5 X-ray contrast media
0.573 0.427 0.000
Y49.2 Other and unspecified antidepressants
0.573 0.427 0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver
0.573 0.427 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.573 0.427 0.000
M80.8 Other osteoporosis with pathological fracture
0.573 0.427 0.000
M80.5 Idiopathic osteoporosis with pathological fracture
0.573 0.427 0.000
M80.4 Drug-induced osteoporosis with pathological fracture
0.573 0.427 0.000
M80.3 Postsurgical malabsorption osteoporosis with pathological fracture
0.573 0.427 0.000
M80.2 Osteoporosis of disuse with pathological fracture
0.573 0.427 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.572 0.428 0.000
Y45.1 Salicylates
0.572 0.428 0.000
M25.67 Stiffness of joint, not elsewhere classified (Ankle and foot)
0.571 0.428 0.000
Y04 Assault by bodily force
0.570 0.430 0.000
C04 Malignant neoplasm of floor of mouth
0.569 0.430 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.568 0.432 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.568 0.432 0.000
A75-A79 Rickettsioses
0.568 0.432 0.000
A70-A74 Other diseases caused by chlamydiae
0.568 0.432 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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